Mammalian protein Kinases |
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# |
NAME |
Sp |
na ACC# |
na ACC# link |
Name/Notes |
Super-family |
Group |
Family |
Homology (AA:AA unless indicated) |
aa ACC# |
aa ACC# |
aa |
CHR location |
|
1 |
AKT_h |
H |
M63167 |
M63167 |
RACa_h (AKT) |
Protein kinase |
AGC |
AKT |
|
NP_005154 |
NP_005154 |
480 |
14q32.3 (OMIM) |
|
|
2 |
AKT2_h |
H |
M77198 |
M77198 |
RACb_h; PKBb; AKT2 |
Protein kinase |
AGC |
AKT |
|
AAA36585 |
AAA36585 |
520 |
19q13.1-13.2 (Factsbook) |
|
|
3 |
AKT3_h |
H |
AA017141 |
AA017141 |
RACg_h; AKT3 |
Protein kinase |
AGC |
AKT |
43aa RAC g_r 95% RACa_h 85% |
NP_005456 |
NP_005456 |
479 |
NA |
|
4 |
PDK1_h |
H |
AF017995 |
AF017995 |
PDK1, PKB |
Protein kinase |
AGC |
AKT |
262aa PKACb_h 39%; PKCa 38%; Racb_h 39% |
NP_0026204 |
NP_0026204 |
556 |
16p13.3 (gene list) |
|
|
|
5 |
PK428_h |
H |
U59305 |
U59305 |
PK428_h, MRCK_r; mytonic dystrophy
kinase Cdc42-bind |
Protein kinase |
AGC |
DMPK |
DMPK2_h 98%; MRCKb_r 76% |
NP_003598 |
NP_003598 |
496 |
1q41-42 (ref UI: 97248557 ) |
|
6 |
CITRON-K |
M |
AF070066 |
AF070066 |
Citron Kinase, Nature 394; 491-494 (1998) |
Protein kinase |
AGC |
DMPK |
|
AAC27933 |
AAC27933 |
1641 |
NA |
|
|
|
7 |
DMPK_h |
H |
M87312 |
M87312 |
Myotonic dystrophy (MTPK), DMK, MT-PK,
DM-KINASE |
Protein kinase |
AGC |
DMPK |
|
Q09013 |
Q09013 |
639 |
19q13.3 (gene list) |
|
8 |
DMPK2_h |
H |
Y12337 |
Y12337 |
DMPK2_h |
Protein kinase |
AGC |
DMPK |
288aa MRCK_r 74%; PK428_h 73%; MRCKb_r 71% |
CAA73006 |
CAA73006 |
289 |
11q13 (entrez 2217968) |
|
9 |
MRCKb_h |
H |
NM_006035 |
NM_006035 |
MRCKb_h, CDC42BP, myotonic dystrophy
kinase-related CDC42-binding protein kinase beta, Genghis Khan_dm |
Protein kinase |
AGC |
DMPK |
135aa MRCKb_r 100%; PK428_h 88% |
NP_006026 |
NP_006026 |
1711 |
NA |
|
|
|
10 |
p160 ROCK2_h |
H |
AA570565 |
AA570565 |
p160 ROCK2_h |
Protein kinase |
AGC |
DMPK |
135aa p160ROCK_m 94% |
NP_004841 |
NP_004841 |
1388 |
NA |
|
11 |
ROCK1_h |
H |
U43195 |
U43195 |
Rho-assoc_coiled-coil_kinase_1 |
Protein kinase |
AGC |
DMPK |
|
NP_005397 |
NP_005397 |
1354 |
NA |
|
|
12 |
GRKpsu_h |
H |
U48958 |
U48958 |
GRKpsu_h |
Protein kinase |
AGC |
GRK |
|
psu |
psu |
na |
NA |
|
13 |
RHODK_h |
H |
U63973 |
U63973 |
Rhodopsin kinase, RHOK, GRK1 |
Protein kinase |
AGC |
GRK |
|
NP_002920 |
NP_002920 |
563 |
13q34 (gene list) |
|
|
|
14 |
BARK1A_h |
H |
M80776 |
M80776 |
BARK1A_h |
Protein kinase |
AGC |
GRK |
|
NP_001610 |
NP_001610 |
689 |
11q13 (GDB Gene List) |
|
15 |
BARK2_h |
H |
X69117 |
X69117 |
BARK2_h |
Protein kinase |
AGC |
GRK |
|
CAA48870 |
CAA48870 |
688 |
22q11 (GDB Gene list) 11q13 conflict |
|
|
16 |
GRK4_h |
H |
U33054 |
U33054 |
GRK4_h, GPRK4 |
Protein kinase |
AGC |
GRK |
|
AAC50406 |
AAC50406 |
578 |
4p16.3 (gene list) |
|
|
17 |
GRK5_h |
H |
L15388 |
L15388 |
GRK5_h |
Protein kinase |
AGC |
GRK |
|
AAA58620 |
AAA58620 |
590 |
10q24-10qter (gene list) |
|
18 |
GRK6_h |
H |
L16862 |
L16862 |
GRK6_h |
Protein kinase |
AGC |
GRK |
|
AAA60175 |
AAA60175 |
576 |
5q35-5qter (gene list) |
|
19 |
GRK7_sq |
SQ |
AAC95001 |
AAC95001 |
GRK7 G protein-coupled receptor kinase |
Protein kinase |
AGC |
GRK |
258/526 (49%) GRK6_h |
AF063016 |
AF063016 |
548 |
|
20 |
KIAA0303_h |
H |
AB002301 |
AB002301 |
KIAA0303, MAST205 |
Protein kinase |
AGC |
MAST |
KIAA0303_h 100%
MAST205_m 91% |
2224547 |
2224547 |
2137 |
5q12 (U) |
|
|
21 |
KIAA0561_h |
H |
AB011133 |
AB011133 |
KIAA0561, R32140_1 |
Protein kinase |
AGC |
MAST |
274aa KIAA0303_h 90%; MAST205_m 90% |
BAA25487 |
BAA25487 |
1308 |
19p13.2 (E) |
|
|
|
22 |
SAST_h |
H |
AB023190 |
AB023190 |
KIAA0973, SAST, syntrophin-associated
STK, AF077818_m |
Protein kinase |
AGC |
MAST |
|
BAA76817 |
BAA76817 |
1583 |
|
23 |
MNK1_h |
H |
NM_003684 |
NM_003684 |
MNK1, MAPK interacting kinase, MAP
kinase-activated protein kinase |
Protein kinase |
AGC |
MNK |
|
NP_003675 |
NP_003675 |
424 |
1p31.1-32.3 (U) |
|
24 |
MNK2_h |
H |
AA159268 |
AA159268 |
MNK2 |
Protein kinase |
AGC |
MNK |
|
AAD21217 |
AAD21217 |
472 |
19ptel (U) |
|
|
25 |
I38214_h |
H |
Z25424 |
Z25424 |
34aa PCR frag |
Protein kinase |
AGC |
MNK |
34aa MNK1 82% |
CAA80911 |
CAA80911 |
34 |
NA |
|
26 |
KIAA0151_h |
H |
D63485 |
D63485 |
KIAA0151 |
Protein kinase |
AGC |
Mo3C11.1_ce |
372aa IKKb_h & IKKa_h 27%; ULK_h 31% |
BAA09772 |
BAA09772 |
716 |
1q31 (U) |
|
27 |
T2K |
M |
AAD34590 |
AAD34590 |
T2K protein kinase homolog |
Protein kinase |
AGC |
Mo3C11.1_ce |
351/717
(48%) KIAA0151_h; 98/356 (27%) IKKb_h
|
AF145705 |
AF145705 |
729 |
|
28 |
TEST1 |
H |
Z21326 |
Z21326 |
TEST1, AAADYRP, KIAA0151-like |
Protein kinase |
AGC |
Mo3C11.1_ce |
53aa KIAA0151 86%;
M03C11.1_ce 42% |
est |
est |
|
NA |
|
29 |
NDR_h |
H |
Z35102 |
Z35102 |
NDR |
Protein kinase |
AGC |
NDR |
|
CAA84485 |
CAA84485 |
465 |
6p21.1-p21.3 (U) |
|
30 |
WART1_h |
H |
NM_004690 |
NM_004690 |
WART1, lats1_h |
Protein kinase |
AGC |
NDR |
|
NP_004681 |
NP_004681 |
1130 |
6q22.3 (U) |
|
31 |
WART2_h |
H |
SUGEN |
SUGEN |
WART2_h |
Protein kinase |
AGC |
NDR |
|
SUGEN |
SUGEN |
|
12p13.1-13.3 |
|
|
32 |
PKX1_h |
H |
X85545 |
X85545 |
PKX1 |
Protein kinase |
AGC |
PKA |
272aa PRKY_h 92%;
DC2_dm 62%; PKACb_h 55% |
P51817 |
P51817 |
358 |
Xp22.3 |
|
33 |
PKACa_h |
H |
X07767 |
X07767 |
PKACa |
Protein kinase |
AGC |
PKA |
|
CAA30597 |
CAA30597 |
351 |
19p13.1 (gene list) |
|
34 |
PKACb_h |
H |
M34181 |
M34181 |
PKACb |
Protein kinase |
AGC |
PKA |
|
AAA60170 |
AAA60170 |
351 |
1p36.1 (gene list) |
|
|
35 |
PKACg_h |
H |
M34182 |
M34182 |
PKACg |
Protein kinase |
AGC |
PKA |
|
AAC41690 |
AAC41690 |
360 |
9q13 |
|
|
36 |
PKA-Cxpsu |
M |
S75484 |
S75484 |
PKA-Cxpsu |
Protein kinase |
AGC |
PKA |
|
psu |
psu |
|
M |
|
37 |
PRKXpsu_h |
H |
Y10483 |
Y10483 |
PRKXpsu_h Pseudogene |
Protein kinase |
AGC |
PKA |
140aa PKX1_h 75%; DC2_dm |
psu |
psu |
na |
15q26 |
|
38 |
PRKY_h |
H |
Y13927 |
Y13927 |
PRKX, PRKY, PKX1-like |
Protein kinase |
AGC |
PKA |
|
2695984 |
2695984 |
277 |
Yp11.2 (E) |
|
39 |
CAB43292_h |
H |
AL050147 |
AL050147 |
PKCmu? DKFZp586E0820, Contig w
AA290809 |
Protein kinase |
AGC |
PKC |
PKC mu 87.3% good seq |
CAB43292 |
CAB43292 |
542 |
19q13.1-q13.3 (U) |
|
|
|
40 |
EPK2_h |
H |
AB015982 |
AB015982 |
PKD_h EPK2, PKCnu, a new member of
the protein kinase C family, composes a fourth subfamily with PKC&mgr;1 |
Protein kinase |
AGC |
PKC |
|
NP_005804 |
NP_005804 |
890 |
|
41 |
EPK2_m |
M |
AA939863 |
AA939863 |
EPK2_h1 (AB015982) EPK2, PKCnu, a
new member of the protein kinase C family, composes a fourth subfamily with
PKC&mgr;1 |
Protein kinase |
AGC |
PKC |
109aa 97% EPK2_h 328bp 91% |
est |
est |
na |
M |
|
42 |
PCKl_h |
H |
M55284 |
M55284 |
PKC lambda |
Protein kinase |
AGC |
PKC |
|
AAA60100 |
AAA60100 |
682 |
14 (U) |
|
|
|
43 |
PKCa_h |
H |
X52479 |
X52479 |
PKC alpha |
Protein kinase |
AGC |
PKC |
|
CAA36718 |
CAA36718 |
672 |
17q24.3 (G) 17q22-17q23.2
(g list) |
|
44 |
PKCb_h |
H |
M27546 |
M27546 |
PKC beta |
Protein kinase |
AGC |
PKC |
|
CAA30130 |
CAA30130 |
673 |
16p12.1 (G) |
|
45 |
PKCd_h |
H |
D10495 |
D10495 |
PKC delta |
Protein kinase |
AGC |
PKC |
|
BAA01381 |
BAA01381 |
626 |
3p14.3 (U) |
|
46 |
PKCe_h |
H |
X65293 |
X65293 |
PKC epsilon |
Protein kinase |
AGC |
PKC |
|
CAA46388 |
CAA46388 |
737 |
NA |
|
47 |
PKCg_h |
H |
Z15114 |
Z15114 |
PKC gamma |
Protein kinase |
AGC |
PKC |
|
CAA78820 |
CAA78820 |
536 |
19q13.4 (gene list) |
|
|
|
48 |
PKCi_h |
H |
L33881 |
L33881 |
PKC iota |
Protein kinase |
AGC |
PKC |
|
AAB17011 |
AAB17011 |
587 |
Xq21.3 (gene list iota) |
|
49 |
PKCm_h |
H |
X75756 |
X75756 |
PKC mu |
Protein kinase |
AGC |
PKC |
|
CAA53384 |
CAA53384 |
912 |
14q11.2-12 (U) |
|
50 |
PKCt_h |
H |
L01087 |
L01087 |
PKC theta |
Protein kinase |
AGC |
PKC |
|
AAA75571 |
AAA75571 |
706 |
10p15 (gene list) |
|
|
|
51 |
PKCz_h |
H |
Z15108 |
Z15108 |
PKC zeta |
Protein kinase |
AGC |
PKC |
|
CAA78813 |
CAA78813 |
584 |
1p36.3 (U) |
|
52 |
PKD_m |
M |
Z34524 |
Z34524 |
PKD |
Protein kinase |
AGC |
PKC |
918aa PKCmu_h 92% |
CAA84283 |
CAA84283 |
918 |
M |
|
53 |
PRK1_h |
H |
S75546 |
S75546 |
PRK1, PKN, DBK, PRK1.1 |
Protein kinase |
AGC |
PKC |
942aa PRK1_h (PKN) 59% |
I53327 |
I53327 |
942 |
19p12-13.1 (U) |
|
|
|
54 |
PRK2_h |
H |
S75548 |
S75548 |
PRK2 |
Protein kinase |
AGC |
PKC |
942aa PRK1_h (PKN) 59% |
AAB33346 |
AAB33346 |
984 |
1p31.1 (G) 262cR from top |
|
|
|
55 |
Z25429 |
H |
Z25429 |
Z25429 |
SETHKNI (I38219) |
Protein kinase |
AGC |
PKC |
164aa PKCmu_h 93%: 58aa I38219_h 100% |
CAA80916 |
CAA80916 |
67 |
NA |
|
56 |
CGK_h |
H |
Y07512 |
Y07512 |
CGMP1, PKG_h, KGPB_h, CGK, PRKG1
(was CGK_h) CGMP-DEPENDENT PROTEIN KINASE, BETA ISOZYME |
Protein kinase |
AGC |
PKG |
|
CAA68810 |
CAA68810 |
686 |
10q11.2 (gene list) |
|
57 |
cGMPk_h |
H |
X94612 |
X94612 |
PRKG2 |
Protein kinase |
AGC |
PKG |
|
BAA08297 |
BAA08297 |
671 |
4q13.1-4q21.1 (gene list) |
|
58 |
cGMPKII_h |
H |
AA913837 |
AA913837 |
cGMPKII |
Protein kinase |
AGC |
PKG |
145aa cGMPKPh 100% |
NP_006250 |
NP_006250 |
762 |
4q21.1-q21.2 (U) |
|
59 |
AAD30182 |
H |
AC006530 |
AC006530 |
5/13/1999 - Genomic |
Protein kinase |
AGC |
S6K |
RSK3_m 71/172 (41%) & 42/143 (29%) |
AAD30182 |
AAD30182 |
549 |
|
60 |
MSK1_h |
H |
NM_004755 |
NM_004755 |
MSK1_h, RSK-like protein kinase RLPK,
nuclear mitogen- and stress-activated protein kinase-1 |
Protein kinase |
AGC |
S6K |
153aa S6K_h 61%; T01H8.1b _ce 62% |
NP_004746 |
NP_004746 |
809 |
NA |
|
|
61 |
MSK2_h |
H |
NM_003942 |
NM_003942 |
MSK2_h, RSK-B, mitogen- and stress-activated
protein kinase-2, ribosomal protein S6 kinase, 90kD, polypeptide 4 |
Protein kinase |
AGC |
S6K |
710aa MSK1_h 71%; RSK3_h 43% |
NP_003933 |
NP_003933 |
772 |
Xp22 (Entrez) |
|
|
|
62 |
p70S6K_h |
H |
M60724 |
M60724 |
p70S6KaII_h |
Protein kinase |
AGC |
S6K |
|
AAA36410 |
AAA36410 |
525 |
17q23.1-17q24.1 (G) |
|
|
63 |
p70S6Kb_h |
H |
NM_003952 |
NM_003952 |
p70S6 kinase b, p70 ribosomal S6 kinase
beta, SRK, RPS6KB2 |
Protein kinase |
AGC |
S6K |
|
NP_003943 |
NP_003943 |
495 |
|
|
|
64 |
RSK1_h |
H |
X85106 |
X85106 |
RSK_h; S6K2 |
Protein kinase |
AGC |
S6K |
|
CAA59427 |
CAA59427 |
733 |
3pter-3qter (gene list) |
|
|
|
65 |
RSK2_h |
H |
U08316 |
U08316 |
RSK2_h; ISPK-1 (insulin-stimulated) S6KII-a, p90RSK2 |
Protein kinase |
AGC |
S6K |
|
AAA81952 |
AAA81952 |
740 |
Xp21.3-22.1 (Entrez)
Chr1, 94.8cR (U) |
|
|
66 |
RSK3_h |
H |
L07597 |
L07597 |
RSK3_h, ribosomal protein S6 kinase
3_m, p90 S6 kinase_r |
Protein kinase |
AGC |
S6K |
|
AAC82497 |
AAC82497 |
735 |
6q27 (gene list) |
|
|
67 |
MAST205_m |
M |
U02313 |
U02313 |
MAST205_m |
Protein kinase |
AGC |
SGK |
274aa - AB002301_h 91% |
AAC04312 |
AAC04312 |
1734 |
M |
|
|
68 |
SGK_h |
H |
Y10032 |
Y10032 |
SGK |
Protein kinase |
AGC |
SGK |
431aa SGK_r 96%; W10G6.2_ce 52%; AKT_m 46% |
CAA71138 |
CAA71138 |
431 |
6q21-q22.1 |
|
|
69 |
A6_h |
H |
U02680 |
U02680 |
A6 tyrosine kinase |
Protein kinase |
Atypical |
A6 |
350aa A6_m (U82324) 94%; U46668_ce 31%; YGR080w_sc 26% |
A55922 |
A55922 |
350 |
12 (U) |
|
70 |
EEF-2K |
H |
U93850 |
U93850 |
Elongation factor kinase, Myosin heavy
chain kinase |
Protein kinase |
Atypical |
MHCK |
|
O00418 |
O00418 |
725 |
|
|
|
71 |
BCKDK_h |
H |
NM_005881 |
NM_005881 |
BCKDK, branched chain alpha-ketoacid
dehydrogenase kinase |
Protein kinase |
Atypical |
PDK |
|
NP_005872 |
NP_005872 |
412 |
|
|
72 |
PDK1_h |
H |
L42450 |
L42450 |
PDK1,
pyruvate dehydrogenase kinase isoenzyme 1 |
Protein kinase |
Atypical |
PDK |
|
Q15118 |
Q15118 |
436 |
|
|
73 |
PDK2_h |
H |
NM_002611 |
NM_002611 |
PDK2, pyruvate dehydrogenase kinase
isoenzyme 2 |
Protein kinase |
Atypical |
PDK |
|
NP_002602 |
NP_002602 |
407 |
|
|
74 |
PDK3_h |
H |
NM_005391 |
NM_005391 |
PDK3, pyruvate dehydrogenase kinase
isoenzyme 3 |
Protein kinase |
Atypical |
PDK |
|
NP_005382 |
NP_005382 |
406 |
|
|
75 |
PDK4_h |
H |
NM_002612 |
NM_002612 |
PDK4, pyruvate dehydrogenase kinase
isoenzyme 4 |
Protein kinase |
Atypical |
PDK |
|
NP_002603 |
NP_002603 |
411 |
|
|
76 |
BCR_h |
H |
X02596 |
X02596 |
Domains=PH, C2, GAP (for p21-Rac) |
Protein kinase |
Atypical |
Unique |
|
P11274 |
P11274 |
1271 |
22q11 |
|
77 |
FAST_h |
H |
X86779 |
X86779 |
FAST, fas-activated STK (substrate=TIA1) |
Protein kinase |
Atypical |
Unique |
232aa CPR2_h 30% |
I37386 |
I37386 |
549 |
7q32-q36 (EST=AI126915) |
|
|
78 |
GS3955_h |
H |
D87119 |
D87119 |
GS3955 |
Protein kinase |
CAMK |
AMPK |
226aa
GS3955_h (D87119) 100%; AJ000480_h
71%; PK38_m 32% |
BAA13250 |
BAA13250 |
343 |
2p23-p22 (U) |
|
|
79 |
PK38_h |
H |
D79997 |
D79997 |
PK38_h, MELK_m |
Protein kinase |
CAMK |
AMPK |
KIAA0175_h
100% PK38_m 99% AMPKa1_r 49% |
BAA11492 |
BAA11492 |
651 |
9q11 (U) |
|
|
|
80 |
AMPKa1_h |
H |
H96775 |
H96775 |
AMPKa1 |
Protein kinase |
CAMK |
AMPK |
131aa AMPKa1_r 98%
AMPK_h 89% |
NP_006242 |
NP_006242 |
550 |
5p14-5p11 (gene list) |
|
81 |
AJ006701_h |
H |
AJ006701 |
AJ006701 |
AJ006701_h, PEN11B_h, F15A2.6_ce? |
Protein kinase |
CAMK |
AMPK |
444aa AJ006701_h, 97% (1950bp 99%); F15A2.6_ce48%; YKL101W_sc
42% |
CAA04119 |
CAA04119 |
224 |
11p15 |
|
82 |
AMPK2_h |
H |
U22456 |
U22456 |
AMPK2, AAK2 |
Protein kinase |
CAMK |
AMPK |
|
726313 |
726313 |
108 |
NA |
|
|
83 |
AMPKa2_h |
H |
U06454 |
U06454 |
AMPKa2 |
Protein kinase |
CAMK |
AMPK |
|
AAA64745 |
AAA64745 |
552 |
1p31 (gene list) |
|
|
84 |
AUF1_h
|
H |
U56659 |
U56659 |
AUF1, AU-rich RNA binding protein |
Protein kinase |
CAMK |
AMPK |
440 naAUF1_h 95%; PK38_m/Melk 38% |
NP_002129 |
NP_002129 |
286 |
NA |
|
|
|
85 |
NIPK |
R |
BAA77582 |
BAA77582 |
NIPK induced by NGF-depletion |
Protein kinase |
CAMK |
AMPK |
155/290 (53%) GS3955_h |
AB020967 |
AB020967 |
349 |
|
|
|
86 |
U13258 |
M |
U13258 |
U13258 |
ink76_m partial GB 1994 |
Protein kinase |
CAMK |
AMPK |
64aa - AMPKa_h 84.4%; |
est |
est |
|
M |
|
|
87 |
AL049688 |
H |
AL049688 |
AL049688 |
Ca2+/Calmodulin dependent Protein Kinase
LIKE protein, CAA19296.1_h, BAA19880_r |
Protein kinase |
CAMK |
CAMK |
|
CAB41259 |
CAB41259 |
481 |
|
|
|
|
88 |
CaMKI_h |
H |
L41816 |
L41816 |
CAMK1 |
Protein kinase |
CAMK |
CAMK |
314aa CaMKIb2_r 69%; CaMKIV_h 49% |
Q14012 |
Q14012 |
370 |
3p24.2-p21.3 (U) |
|
89 |
CaMKIb2_h |
H |
R87839 |
R87839 |
CAMK1b2 |
Protein kinase |
CAMK |
CAMK |
161 aa CAMKIb2_r 97%, 480 bp 89% |
BAA19879_r |
BAA19879_r |
342 |
NA |
|
90 |
CaMKIIa_h |
H |
AA984784 |
AA984784 |
CaMKIIa |
Protein kinase |
CAMK |
CAMK |
90aa CaMKIIa_m 100% in
C-term |
BAA76812 |
BAA76812 |
527 |
NA |
|
91 |
CaMKIIb_h |
H |
AA399393 |
AA399393 |
CaMKIIb_h |
Protein kinase |
CAMK |
CAMK |
169aa CAMKIIb_m 99.4% |
AAD03743 |
AAD03743 |
517 |
22q12 (LocusLink) |
|
92 |
CaMKIId_h |
H |
AA316038 |
AA316038 |
CaMKIId_h |
Protein kinase |
CAMK |
CAMK |
155aa CKII delta 2_r 99% |
AAD20442 |
AAD20442 |
499 |
NA |
|
|
|
93 |
CaMKIIg_h |
H |
L07044 |
L07044 |
CaMKIIg (+isoforms) |
Protein kinase |
CAMK |
CAMK |
|
B46619 |
B46619 |
518 |
10q22 (LocusLink) |
|
|
94 |
CAMKL_h |
H |
AA082976 |
AA082976 |
Calmodulin-BP_r (I56542), 1G5 |
Protein kinase |
CAMK |
CAMK |
60aa Calmod bind_r (I56542_r), 100%; 90aa CAMKI_h 42% |
AAA16633_r |
AAA16633_r |
504 |
NA |
|
95 |
CAMKL1_h |
H |
NM_004734 |
NM_004734 |
KIAA0369, CPG16_r, doublecortin (lissencephalin-X;
LISX ) and CaM kinase-like 1, AL110501_ce |
Protein kinase |
CAMK |
CAMK |
281aa CAMK1_h 46% |
NP_004725 |
NP_004725 |
729 |
13q13 (U) |
|
|
96 |
CASK_h |
H |
AF035582 |
AF035582 |
CASK, CASK-B, lin-2, CAMGUK |
Protein kinase |
CAMK |
CAMK |
268aa CASKb_m 100%
CAMKIId_r 48% |
AAA64745 |
AAA64745 |
897 |
Xp11.4 (LocusLink) |
|
|
|
97 |
CHK2_h |
H |
AF086904 |
AF086904 |
CHK2_h w FHA domain, HuCds |
Protein kinase |
CAMK |
CHK2 |
CaMK, 21/32 (65%) |
AAC83693 |
AAC83693 |
543 |
|
98 |
DAPK_h |
H |
X76104 |
X76104 |
DAPK_h |
Protein kinase |
CAMK |
DAPK |
|
CAA53712 |
CAA53712 |
1431 |
9q34.1 (gene list) |
|
|
99 |
DAPKRP1_h |
H |
AA858002 |
AA858002 |
DAPKRP1 |
Protein kinase |
CAMK |
DAPK |
123aa DAPK_h 78%; 78%na to N23936 |
AAC35001 |
AAC35001 |
370 |
NA |
|
|
100 |
DRAK1 |
H |
NM_004760 |
NM_004760 |
DRAK1, related to death-associated
protein kinase that trigger apoptosis |
Protein kinase |
CAMK |
DAPK |
107aa DAPK_h 47% SUGEN 8/3/98 GB:11/5/98 |
NP_004751 |
NP_004751 |
414 |
7p11.1-q11.1 (U) |
|
|
|
101 |
DRAK2_h |
H |
NM_004226 |
NM_004226 |
DRAK2, related to death-associated
protein kinase that trigger apoptosis |
Protein kinase |
CAMK |
DAPK |
81%na to AA538060_m, SUGEN:7/23/98, GB:11/5/98 |
NP_004217 |
NP_004217 |
372 |
NA |
|
102 |
ZIP_h |
H |
AB001872 |
AB001872 |
LZK, ZIP, DAPK3 |
Protein kinase |
CAMK |
DAPK |
|
BAA24817 |
BAA24817 |
966 |
19p13.3 (LocusLink) |
|
|
|
103 |
KIAA0135 _h |
H |
D50925 |
D50925 |
KIAA0135 |
Protein kinase |
CAMK |
EMK |
263aa KIAA0135_h 100%
YAL017W_sc 39% TAK 35% |
BAA09484 |
BAA09484 |
1241 |
2q34-q37.2 (U) |
|
|
104 |
KIAA0096_h |
H |
D43636 |
D43636 |
KIAA0096_h |
Protein kinase |
CAMK |
EMK |
34aa KIAA0096_h 76% (SNF1_r) |
BAA07744 |
BAA07744 |
527 |
3p22.1 (G) |
|
105 |
C-TAK1 |
H |
M80359 |
M80359 |
C-TAK1, MARK3, Kp78, cTAK75a |
Protein kinase |
CAMK |
EMK |
|
AAC15093 |
AAC15093 |
729 |
14q32.1-32.3 (U) |
|
|
106 |
EMK_h |
H |
X97630 |
X97630 |
EMK_h, ELKL motif kinase 1, KEM_m,
MARK2_r |
Protein kinase |
CAMK |
EMK |
|
CAA66229 |
CAA66229 |
745 |
11q12-11q13 (gene list) |
|
|
107 |
KIAA0537_h |
H |
AB011109 |
AB011109 |
KIAA0537_h human orthologue of B04496_ce |
Protein kinase |
CAMK |
EMK |
84 aa B0496_ce 64%,60 aa p78_h 55% |
BAA25463 |
BAA25463 |
661 |
12q22 (U) |
|
|
|
108 |
KIAA0999 |
H |
AB023216 |
AB023216 |
KIAA0999 |
Protein kinase |
CAMK |
EMK |
86/310 (60%) MSK_m/SIK_r |
BAA76843 |
BAA76843 |
1102 |
|
109 |
MAK-V_h |
H |
AA426580 |
AA426580 |
MAK-V_m (AF055919), R25-38-5_m |
Protein kinase |
CAMK |
EMK |
300aa MAK-V_m >91%; SPCC74_sp 48%; TAK1_h 31% |
AF055919 |
AF055919 |
714_m |
21q11.1 (AP000036) |
|
|
110 |
MARK1_h |
H |
Z83868 |
Z83868_r |
MARK1_r |
Protein kinase |
CAMK |
EMK |
181aa TAK1_h 90%, 492bp MARK1_r 91% |
CAB06294 |
CAB06294 |
793_r |
NA |
|
|
111 |
MSK_m |
M |
U11494 |
U11494 |
MSK, HRT-20, Myocardial SNF1-like
kinase |
Protein kinase |
CAMK |
EMK |
80aa p78_h 60% |
Q60670 |
Q60670 |
481 |
M |
|
112 |
SNRK_h |
H |
AA832179 |
AA832179 |
SNRK_h |
Protein kinase |
CAMK |
EMK |
SNRK_r >98%
SNF-related |
CAA61563 |
CAA61563 |
746_r |
NA |
|
|
113 |
MAPKAPK2_h |
H |
U12779 |
U12779 |
MAPKAPK2, MKK2 |
Protein kinase |
CAMK |
MAPKAP |
|
P49137 |
P49137 |
370 |
1q32.1-q32.2 (G) |
|
114 |
MAPKAPK3_h |
H |
U09578 |
U09578 |
MAPKAPK3, 3PK |
Protein kinase |
CAMK |
MAPKAP |
|
AAD09136 |
AAD09136 |
382 |
3p21.3 (G) |
|
|
115 |
MAPKAPK5_h |
H |
NM_003668 |
NM_003668 |
MAPKAPK5, PRAK, PRK |
Protein kinase |
CAMK |
MAPKAP |
132aa MAPKAP2_h 50%;
MAPKAPK3_h 44%; CAMK4_h 39% |
NP_003659 |
NP_003659 |
471 |
12q22 (U) |
|
116 |
MLCK_h |
H |
U48959 |
U48959 |
MLCK |
Protein kinase |
CAMK |
MLCK |
|
AAC18423 |
AAC18423 |
1914 |
3q13.3 (U) |
|
|
117 |
MLCKs |
R |
J03886 |
J03886 |
Myosin LCK skel muscle |
Protein kinase |
CAMK |
MLCK |
99aa MLCK_rat 97% |
AAA41625 |
AAA41625 |
610_r |
|
118 |
Titin_h |
H |
X92412 |
X92412 |
Titin |
Protein kinase |
CAMK |
MLCK |
|
NP_003310 |
NP_003310 |
26926 |
2q31 (E) |
|
119 |
PHKG1_h |
H |
X80590 |
X80590 |
PHKG1, phosphorylase kinase gamma 1 |
Protein kinase |
CAMK |
PHK |
271aa - PHKG1-Testis_h 71% Exact to skel mus form |
Q16816 |
Q16816 |
387 |
7p12-7q21 (gene list) |
|
120 |
PHKgT_h |
H |
M31606 |
M31606 |
PHKgT, PHKG2, PSK-C3, phosphorylase
kinase gamma 2 |
Protein kinase |
CAMK |
PHK |
372aa PHKG1_h 64%; CAMKI_r 39% |
P15735 |
P15735 |
406 |
16p12.1-p11.2 (U) |
|
|
121 |
PSK-H1_h |
H |
X71875 |
X71875 |
PSK-H1 |
Protein kinase |
CAMK |
PHK |
|
406242 |
406242 |
319 |
NA |
|
122 |
Trio_h |
H |
U42390 |
U42390 |
Trio |
Protein kinase |
CAMK |
Trio |
Trio_h 100% DAPK1_h 42% |
1353703 |
1353703 |
2861 |
5p15.1-p14 (ref Taviaux) |
|
|
123 |
TRAD_h |
H |
AB011422 |
AB011422 |
TRAD; Duet is a novel STK with dbl-
(DH) and pleckstrin- (PH) domains (3/99) |
Protein kinase |
CAMK |
Trio |
1203aa Trio_h ~50% SUGEN 9/2/98 GB:3/24/99 |
BAA76314 |
BAA76314 |
1289 |
NA |
|
|
124 |
KIAA0369_h |
H |
AB002367 |
AB002367 |
KIAA0369_h CPG16 |
Protein kinase |
CAMK |
Unique |
KIAA0369 _h CAMKI_h 47% |
BAA20824 |
BAA20824 |
729 |
13q13 (U) |
|
125 |
CKIg2_h |
H |
U89896 |
U89896 |
CKIg2, Casein Kinase 1 gamma 2_h |
Protein kinase |
CKI |
CKI |
|
AAB88627 |
AAB88627 |
415 |
19p13.3 (gene list) |
|
126 |
CKIa_h |
H |
L37042 |
L37042 |
casein kin 1 alpha |
Protein kinase |
CKI |
CKI |
|
AAC41760 |
AAC41760 |
337 |
13q13 (gene list) |
|
127 |
CKId_h |
H |
U29171 |
U29171 |
casein kin 1 delta |
Protein kinase |
CKI |
CKI |
|
AAC50807 |
AAC50807 |
415 |
17q25.2-17q25.3 (gene list) |
|
|
128 |
CKIe_h |
H |
L37043 |
L37043 |
casein kin 1 epsilon |
Protein kinase |
CKI |
CKI |
|
AAC41761 |
AAC41761 |
416 |
22q12-22q13 (gene list) |
|
|
129 |
KKIAMRE_h |
H |
U35146 |
U35146 |
KKIAMRE, p56 |
Protein kinase |
CMGC |
CDK |
308aa KKILARE_h 58%; PISSLRE_h 38% |
AAC50918 |
AAC50918 |
493 |
NA |
|
|
|
130 |
CAK_h |
H |
X77743 |
X77743 |
CAK, CDK7, Mo15, STK1, p39 |
Protein kinase |
CMGC |
CDK |
290aa CDK3_h 46% |
P50613 |
P50613 |
346 |
2p15-cen (LocusLink) |
|
131 |
CCRK_h |
H |
AF035013 |
AF035013 |
CCRK cell cycle related kinase |
Protein kinase |
CMGC |
CDK |
462aa CCRK_h (AF035013) 99%, 1331bp 98%; CDK3_h 44% |
AAC98920 |
AAC98920 |
452 |
NA |
|
132 |
CDC2_h |
H |
X05360 |
X05360 |
CDC2, MPF, M-phase kinase, CDK1 |
Protein kinase |
CMGC |
CDK |
|
P06493 |
P06493 |
297 |
10q21.1 (U) |
|
133 |
CDK2_h |
H |
M68520 |
M68520 |
CDK2 |
Protein kinase |
CMGC |
CDK |
|
AAA35667 |
AAA35667 |
298 |
12q13 (gene list) |
|
|
|
134 |
CDK3_h |
H |
X66357 |
X66357 |
CDK3 |
Protein kinase |
CMGC |
CDK |
|
Q00526 |
Q00526 |
305 |
17q22-qter (LocusLink) |
|
|
|
135 |
CDK4_h |
H |
U79269 |
U79269 |
CDK4, PSK-J3 |
Protein kinase |
CMGC |
CDK |
|
P11802 |
P11802 |
303 |
12q13.2-q13.3 (U) 12q14
(LocusLink) |
|
|
136 |
CDK5_h |
H |
X66364 |
X66364 |
CDK5, PSSALRE, TPKII (Tau protein
kinaseII) |
Protein kinase |
CMGC |
CDK |
|
Q00535 |
Q00535 |
291 |
7q36 (gene list) |
|
|
|
137 |
CDK6_h |
H |
X66365 |
X66365 |
CDK6, PLSTIRE |
Protein kinase |
CMGC |
CDK |
|
Q00534 |
Q00534 |
326 |
7q21.1-q21.3 (U) |
|
138 |
CDK8_h |
H |
X85753 |
X85753 |
CDK8_h |
Protein kinase |
CMGC |
CDK |
|
CAA59754 |
CAA59754 |
464 |
13q12 (gene list) |
|
139 |
CHED_h |
H |
M80629 |
M80629 |
CHED, cdc2-related |
Protein kinase |
CMGC |
CDK |
320aa PITALRE_h 46%; CDK3_h 43% |
AAA58424 |
AAA58424 |
418 |
NA |
|
140 |
KIAA0904 |
H |
AB020711 |
AB020711 |
KIAA0904 (2/20/99) CHED! Novel |
Protein kinase |
CMGC |
CDK |
201 aa CHED_h 90% |
BAA74927 |
BAA74927 |
997 |
NA |
|
141 |
KKILARE_h |
H |
X66358 |
X66358 |
KKILARE_h |
Protein kinase |
CMGC |
CDK |
308aa KKIAMRE_h 58%; CDK3_h 43% |
CAA47002 |
CAA47002 |
358 |
NA |
|
|
142 |
PCTAIRE1_h |
H |
X66363 |
X66363 |
PCTAIRE1_h |
Protein kinase |
CMGC |
CDK |
|
S22747 |
S22747 |
496 |
Xp11.3-Xp11.23 (gene list) |
|
143 |
PCTAIRE2_h |
H |
X66360 |
X66360 |
PCTAIRE2_h |
Protein kinase |
CMGC |
CDK |
|
S22746 |
S22746 |
523 |
NA |
|
144 |
PCTAIRE3_h |
H |
X66362 |
X66362 |
PCTAIRE3_h |
Protein kinase |
CMGC |
CDK |
|
CAA47005 |
CAA47005 |
380 |
1q31-1q32 (gene list) |
|
145 |
PFTAIRE_h |
H |
AB020641 |
AB020641 |
PFTAIRE1_h G20041, KIAA0834 |
Protein kinase |
CMGC |
CDK |
218aa PFTAIRE1_m 99% 708bp 91%PFTAIRE_m (95%) |
BAA74857 |
BAA74857 |
451 |
7q21-22 (gene list) |
|
146 |
PISSLRE_h |
H |
X78342 |
X78342 |
PISSLRE, PK2J, CDK10 |
Protein kinase |
CMGC |
CDK |
|
S49330 |
S49330 |
360 |
16q24 (LocusLink) |
|
|
147 |
PITALRE_h |
H |
X80230 |
X80230 |
PITALRE, C-2K, CDK9, P-TEFb kinase |
Protein kinase |
CMGC |
CDK |
320aa CHED 47% |
AAA58424 |
AAA58424 |
418 |
9q34.1 (LocusLink) |
|
148 |
PITSLREa2_h |
H |
M37712 |
M37712 |
PITSLREa2-1,2,3,4,a1,b; PBETA21,22;
P58/GTA; p58clk-1, galactosyltransferase-associated kinase |
Protein kinase |
CMGC |
CDK |
|
P21127 |
P21127 |
439 |
4p14-p15.1 (U) |
|
|
149 |
STK9 |
H |
CAA75342 |
CAA75342 |
STK9, novel sSTK from the Xp22 region |
Protein kinase |
CMGC |
CDK |
|
NP_003150 |
NP_003150 |
1030 |
Xp22 |
|
|
150 |
CLK1_h |
H |
L29219 |
L29219 |
CLK1, CLK1-136, cdc2-cdc28-like |
Protein kinase |
CMGC |
CLK |
|
AAA61480 |
AAA61480 |
484 |
NA |
|
151 |
CLK2_h |
H |
AF023268 |
AF023268 |
L29218 |
Protein kinase |
CMGC |
CLK |
|
AAC51817 |
AAC51817 |
499 |
1q21 (LocusLink) |
|
|
|
152 |
CLK3_h |
H |
L29217 |
L29217 |
CLK3_h |
Protein kinase |
CMGC |
CLK |
|
AAA61484 |
AAA61484 |
490 |
Chr.15 |
|
153 |
CLK4_h |
H |
AA631990 |
AA631990 |
CLK4 |
Protein kinase |
CMGC |
CLK |
322aa CLK4_m 98%, CLK1_h 86% see AA773376 for N-term |
est |
est |
|
NA |
|
154 |
STY |
M |
X57186 |
X57186 |
STY, TF-STY, CLK1_m, nuclear dual
spec kin |
Protein kinase |
CMGC |
CLK |
136aa STY_m 93%; CLK1_h 78% |
A39676 |
A39676 |
483 |
NA |
|
155 |
GSK3a_h |
H |
L40027 |
L40027 |
GSK3a |
Protein kinase |
CMGC |
GSK |
|
AAA62432 |
AAA62432 |
483 |
19q12-q13.4 (U) |
|
|
156 |
GSK3b_h |
H |
L33801 |
L33801 |
GSK3b_h |
Protein kinase |
CMGC |
GSK |
|
AAA66475 |
AAA66475 |
420 |
3q13.3 (U) |
|
|
157 |
ERK1_h |
H |
X60188 |
X60188 |
ERK1, MAPK1, p44MAPK |
Protein kinase |
CMGC |
MAPK |
|
CAA42744 |
CAA42744 |
379 |
16p11.2-16p11.2 (gene list) |
|
158 |
ERK2_h |
H |
Z11695 |
Z11695 |
ERK2, MAPK2, p42MAPK, 40KDAP |
Protein kinase |
CMGC |
MAPK |
|
CAA77753 |
CAA77753 |
348 |
22p11.2-q11.2 (U) |
|
|
159 |
ERK3_h |
H |
X80692 |
X80692 |
ERK3a, p97MAPK_h, p55MAPK_r |
Protein kinase |
CMGC |
MAPK |
464aa 61% ERK4_h; ERK2_h 45%; ERK1_h 44% |
Q16659 |
Q16659 |
721 |
15q21 (ref Meloche) |
|
160 |
ERK4_h |
H |
X59727 |
X59727 |
ERK4, p63MAPK |
Protein kinase |
CMGC |
MAPK |
|
P31152 |
P31152 |
557 |
18q12.3-q21.2 (U) |
|
161 |
ERK5_h |
H |
U29725 |
U29725 |
ERK5, SAPK5, BMK1 |
Protein kinase |
CMGC |
MAPK |
330aa ERK1_h 51%; ERK2_h 51% |
Q13164 |
Q13164 |
816 |
17p11.2-17q11.2 (U) |
|
|
|
162 |
ERK7_r |
R |
AF078798 |
AF078798 |
ERK7_r, 04-FEB-1999, SLT2_sc |
Protein kinase |
CMGC |
MAPK |
452aa SLT2_sc 34$ 340aa ERK1_h 40% |
AAD12719 |
AAD12719 |
546 |
|
|
|
163 |
JNK1a_h |
H |
L26318 |
L26318 |
JNK1a, SAPKg |
Protein kinase |
CMGC |
MAPK |
|
AAA36131 |
AAA36131 |
384 |
10q11.23 (G)
D10S1754-1793 (U) |
|
|
|
164 |
JNK2_h |
H |
U09759 |
U09759 |
JNK2, JNK2a, JNK2b, SAPKa, JNK-55 |
Protein kinase |
CMGC |
MAPK |
|
P45984 |
P45984 |
424 |
5q35 (OMIM) |
|
165 |
JNK3a_h |
H |
U07620 |
U07620 |
JNK3a1, JNK3a2, SAPKb, p54b, p493F12 |
Protein kinase |
CMGC |
MAPK |
|
AAC50101 |
AAC50101 |
422 |
4q21.3 (U) |
|
166 |
NLK_h |
H |
U69562 |
U69562 |
NLK_h, DRES 16 |
Protein kinase |
CMGC |
MAPK |
|
AAC24499 |
AAC24499 |
515_m |
|
|
|
167 |
p38_h |
H |
L35263 |
L35263 |
p38, SAPK2a, CSBP2, Mxi2, MPK2_xl |
Protein kinase |
CMGC |
MAPK |
|
AAA57455 |
AAA57455 |
360 |
6p21.1-p21.3 (U) |
|
168 |
SAPK2b_h |
H |
U53442 |
U53442 |
SAPK2b, p38b2, p38-2 |
Protein kinase |
CMGC |
MAPK |
|
AAB05036 |
AAB05036 |
372 |
NA |
|
|
169 |
SAPK3_h |
H |
Y10487 |
Y10487 |
SAPK3, ERK6, p38gamma |
Protein kinase |
CMGC |
MAPK |
345aa SAPK4_h 66%; p38_h 62% |
CAA71511 |
CAA71511 |
367 |
22q13.3 (gene list) |
|
170 |
SAPK4_h |
H |
NM_002754 |
NM_002754 |
SAPK4_h, p38 delta, PRKM13, stress-activated
protein kinase SAPK4 |
Protein kinase |
CMGC |
MAPK |
|
NP_002745 |
NP_002745 |
365 |
NA |
|
|
|
171 |
KIAA0936 |
H |
AB023153 |
AB023153 |
KIAA0936 |
Protein kinase |
CMGC |
RCK |
|
BAA76780 |
BAA76780 |
632 |
|
|
172 |
MAK_m |
M |
X66983 |
X66983 |
RCK, MAK, MRK; M35863 (exon N) |
Protein kinase |
CMGC |
RCK |
43aa - MAK_m SP:Q04859 |
CAA47392 |
CAA47392 |
622 |
6q22 gene list |
|
|
|
173 |
MOK |
H |
AB022694 |
AB022694 |
MOK protein kinase,
homology to MRK, MAK, MAP kinases (ERK,
p38, JNK/SAPK), Cdks; possesses TEY activation loop |
Protein kinase |
CMGC |
RCK |
129/324 (39%) MHK_at; 121/327 (37%) MAK_m |
BAA81688 |
BAA81688 |
419 |
|
|
174 |
RAGE4_h |
H |
U46194 |
U46194 |
RAGE4_h |
Protein kinase |
CMGC |
Unique |
50aa RAGE-4_h 100%
cdc2_r 40% |
AAB38087 |
AAB38087 |
187 |
14q31-qtel (U) |
|
|
175 |
YAB1 |
H |
AI819411 |
AI819411 |
HYPOTHETICAL HEART PROTEIN |
Protein kinase |
Microbial PK |
ABC1 |
|
est |
est |
|
|
|
176 |
SUDD |
H |
NM_003831 |
NM_003831 |
sudD (suppressor of bimD6, Aspergillus
nidulans) homolog (SUDD) |
Protein kinase |
Microbial PK |
RI01 |
|
NP_003822 |
NP_003822 |
519 |
|
|
177 |
NY-REN-64 |
|
AF155118 |
AF155118 |
putative protein kinase NY-REN-64 antigen
(renal-cell carcinoma), phosphorylates tyrosine, serine and threonine |
Protein kinase |
Other |
APKA_at |
111/283 (39%) APKA_at (and others) |
AAD42884 |
AAD42884 |
460 |
|
178 |
AIE1_m |
M |
AA545317 |
AA545317 |
AIE1_m AUR3 |
Protein kinase |
Other |
AUR |
280aa AUR1_h 78% |
AAC25954 |
AAC25954 |
282 |
M |
|
179 |
AIE2_h |
H |
AF059681 |
AF059681 |
AUR3, STK13, Aik3, AIE2 |
Protein kinase |
Other |
AUR |
67aa AUR1_h 74% |
AAC25955 |
AAC25955 |
275 |
19q13.4 (Lamerdin)
AC005261 |
|
|
|
180 |
AUR1_h |
H |
NM_004217 |
NM_004217 |
AUR1, ARK2_m, STK1_m |
Protein kinase |
Other |
AUR |
|
NP_004208 |
NP_004208 |
344 |
17p13.1 (Plowman) |
|
181 |
AUR2_h |
H |
AF008551 |
AF008551 |
AUR2, BTAK, IAK1_m, AYK1_m, STK15 |
Protein kinase |
Other |
AUR |
|
AAC12708 |
AAC12708 |
403 |
20q13.2 (Plowman) |
|
182 |
AUR1psu_h |
H |
SUGEN |
SUGEN |
AUR1psuedogene |
Protein kinase |
Other |
AURps |
|
psu |
psu |
|
pseudo |
|
|
|
183 |
AUR2psu_h |
H |
AC005383 |
AC005383
|
AUR2 pseudogene, B59754 genomic |
Protein kinase |
Other |
AURps |
|
psu |
psu |
|
pseudo |
|
|
|
184 |
BUB1 |
H |
AF043294 |
AF043294 |
BUB1 |
Protein kinase |
Other |
BUB |
|
AAB97855 |
AAB97855 |
1085 |
2q11.1 (Spencer) |
|
185 |
BUBR1_h |
H |
AF046079 |
AF046079 |
BUBR1, MAD3L, SSK1, BUB1B, MAD3-like
kinase, mitotic checkpoint protein kinase, AF107296_m |
Protein kinase |
Other |
BUB |
514aa BUB1_h 24% |
AAC12730 |
AAC12730 |
1050 |
15q14-21 |
|
|
|
186 |
GSG2_m |
M |
BAA75494 |
BAA75494 |
GSG2, expressed in testicular germ cells |
Protein kinase |
Other |
C26C2.1_ce |
104/286 (36%) F22H10.5_ce |
D87326 |
D87326 |
754 |
|
|
187 |
CaMKIV_h |
H |
D30742 |
D30742 |
CaMKIV, ca/calmod-dep pk IV, CAMKK |
Protein kinase |
Other |
CAMKK |
346aa U11029_ce; SSP1_sp 37% |
BAA04117 |
BAA04117 |
365 |
5q21-5q23 (gene list) |
|
|
188 |
CAMKKB |
H |
AF140507 |
AF140507 |
KIAA0787, CAMKKB Ca2+/calmodulin-dependent
protein kinase kinase beta |
Protein kinase |
Other |
CAMKK |
271aa CAMKIV_r 68%;
U11029_ce 57% |
AAD31507 |
AAD31507 |
588 |
12q23-q14.1 (U) |
|
|
189 |
CHK1_h |
H |
NM_001274 |
NM_001274 |
CHK1_h (checkpoint, S.pombe) homolog |
Protein kinase |
Other |
CHK |
|
NP_001265 |
NP_001265 |
476 |
NA |
|
|
190 |
CKIIa_h |
H |
M55265 |
M55265 |
casein kinase 2, alpha 1 |
Protein kinase |
Other |
CKII |
35aa CKIIa_h 83% |
AAA35503 |
AAA35503 |
391 |
20p13 (gene list) |
|
191 |
CKIIa'_h |
H |
M55268 |
M55268 |
casein kinase 2, alpha
prime |
Protein kinase |
Other |
CKII |
|
AAA51548 |
AAA51548 |
350 |
16q13 (G) |
|
192 |
COT_h |
H |
D14497 |
D14497 |
COT |
Protein kinase |
Other |
COT |
|
P41279 |
P41279 |
467 |
Chr.10, 185.3 cR (U) |
|
|
193 |
DYRK2_h |
H |
Y13493 |
Y13493 |
Dyrk2_h
|
Protein kinase |
Other |
DYRK |
|
CAA73885 |
CAA73885 |
528 |
12q14 (U) |
|
|
194 |
DYRK1B |
H |
NM_004714 |
NM_004714 |
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation
regulated kinase 1B |
Protein kinase |
Other |
DYRK |
377/509 (74%) MNB_h, DYRK_r, DYRK1_h; 168/398 (42%) DYRK2_h |
NP_004705 |
NP_004705 |
629 |
|
195 |
DYRK3_h |
H |
NM_003582 |
NM_003582 |
DYRK3_h
dual-specificity tyrosine-(Y)-phosphorylation
regulated kinase 3 |
Protein kinase |
Other |
DYRK |
Dyrk3_h 100% DYRK2_h 77% |
NP_003573 |
NP_003573 |
553 |
NA |
|
196 |
DYRK4_h |
H |
Y09305 |
Y09305 |
dyrk4 |
Protein kinase |
Other |
DYRK |
Dyrk4_h 100% DYRK2_h 56% |
CAA70488 |
CAA70488 |
240 |
12913.3-p13.2 (U) |
|
197 |
HIPK1_h |
H |
AI188200 |
AI188200 |
HIPK1 (homeodomain-interacting kinase)
see AF077658_m, nuclear body associated kinase 2a, Myak-L_m, Myak-S_m;
similar to yeast YAK1 |
Protein kinase |
Other |
DYRK |
1253 HIPK2_m 63%, HIPK3_m 46%, ANPK_r 46%, PKY_h 46% |
AAC63010 |
AAC63010 |
1209_m |
22p11.2-q11.2 (U) |
|
198 |
HIPK2_m |
M |
AF077659 |
AF077659 |
HIPK2_h, G30814 (STS) see AF077659_m |
Protein kinase |
Other |
DYRK |
1253 HIPK1_m 63% |
AAC63011 |
AAC63011 |
1189 |
7 (E) |
|
|
|
199 |
KIS_h |
H |
AA452389 |
AA452389 |
KIS_r (X98374) KIS_m (Y10725) P-CIP2
(PAM COOH interacting) |
Protein kinase |
Other |
DYRK |
148 aa Dyrk2_h 36%, MNB_dm 37% |
CAA67021 |
CAA67021 |
419_r |
NA |
|
200 |
MNB_h |
H |
D86550 |
D86550 |
MNB_h,dual-specificity kinase, homolog
of Drosophila mnb (minibrain) protein |
Protein kinase |
Other |
DYRK |
|
BAA13110 |
BAA13110 |
754 |
21q22.2 (Ref) |
|
|
201 |
PKY_h |
H |
AF004849 |
AF004849 |
PKY_h AF004849, ANPK_r,
DYRK6, HIPK3_m (homeodomain-interacting protein kinase 3), NBAK3 (nuclear body
associated kinase 3) |
Protein kinase |
Other |
DYRK |
1215aa ANPK_r 88%, U41015_ce
67% |
AAC64294 |
AAC64294 |
1215 |
NA |
|
|
|
202 |
EIF2aK_h |
H |
M35663 |
M35663 |
P1/EIF-2aK, p68K, PKR, IFN-inducible
RNA-dep kinase |
Protein kinase |
Other |
EIFK |
553aa TIK_m 57%;
EIF2aK_r 57% |
O00418 |
O00418 |
725 |
2p21 (U) |
|
|
203 |
EIF2aK_m |
M |
U93848 |
U93848 |
EIF-2aK,TIK, p68K, 65kDa Kinase |
Protein kinase |
Other |
EIFK |
553aa p68K_h 57%; EIF2aK_r 76% |
Q08796 |
Q08796 |
724 |
M |
|
|
204 |
PEK_h |
H |
AF110146 |
AF110146 |
PEK (pancreatic eIF-2 alpha kinase); IFN-inducible (3/12/99), PERK_m (AF076681)
type-I transmembrane ER-resident STK AF096835_r |
Protein kinase |
Other |
EIFK |
57aa F46C3.1_ce 45%;
p68_h 42% |
AAD19961 |
AAD19961 |
1115 |
NA |
|
|
205 |
GAK_h |
H |
D88435 |
D88435 |
GAK, cyclinG-assoc kinase |
Protein kinase |
Other |
GAK |
GAK_h (D88435) 100%
GAK_r 93% |
BAA22623 |
BAA22623 |
1311 |
4p16 (gene list) |
|
206 |
IKKa_h |
H |
AF009225 |
AF009225 |
IKK1, IKK alpha, CHUK,
Helix-loop-helix kinase |
Protein kinase |
Other |
IKK |
718aa IKKb_h 50%; KIAA0151_h
28% |
AAC51671 |
AAC51671 |
745 |
10q24-q25 (gene list) |
|
207 |
IKKb_h |
H |
AF029684 |
AF029684 |
IKKb_h, IkB kinase-b |
Protein kinase |
Other |
IKK |
190aa IKKb_h 100% IKKa_h 71% |
AAC51860 |
AAC51860 |
756 |
NA |
|
208 |
ILK_h |
H |
U40282 |
U40282 |
Beta ILK, Integrin linked kinase |
Protein kinase |
Other |
ILK |
ILK_h 100%; CTR1_at
28% |
AAC16892 |
AAC16892 |
452 |
11p15.5-11p15.4 (gene list) |
|
|
|
209 |
IRAK_h |
H |
L76191 |
L76191 |
IRAK |
Protein kinase |
Other |
IRAK |
|
AAC41949 |
AAC41949 |
712 |
Xq28 (gene list) |
|
|
210 |
IRAK2_h |
H |
NM_001570 |
NM_001570 |
IRAK2 interleukin-1 receptor-associated
kinase 2 |
Protein kinase |
Other |
IRAK |
IRAK2_h 100%IRAK1_h 28% |
NP_001561 |
NP_001561 |
590 |
3p24.2-p21.3 (U) |
|
211 |
IRAK-M_h |
H |
AF113136 |
AF113136 |
IRAK-M, IL-1 receptor-associated-kinase-M |
Protein kinase |
Other |
IRAK |
|
AAD40879 |
AAD40879 |
596 |
|
212 |
IRE1_h |
H |
AF059198 |
AF059198 |
IRE1, bifunctional kinase/endoribonuclease
(Ire1p), ERN1, ER to nucleus
signalling 1 |
Protein kinase |
Other |
IRE |
402aa YOG4_ce; IRE1_sc 41%;
54%CAMKIId_r 29%; PLK1_h 26% |
AAC25991 |
AAC25991 |
977 |
NA |
|
|
|
213 |
LIMK2_h |
H |
D45906 |
D45906 |
LIMK2_h, LIM Kinase 2 |
Protein kinase |
Other |
LIMK |
|
BAA08312 |
BAA08312 |
638 |
22q12 (gene list) |
|
|
214 |
TESK1_h |
H |
D50863 |
D50863 |
testis-specific kinase |
Protein kinase |
Other |
LIMK |
200 aa 47% LIMK1_h |
BAA09459 |
BAA09459 |
626 |
9p13 (gene list) conflict
(shgc-9810 maps to chr11) |
|
215 |
LIMK1_h |
H |
U63721 |
U63721 |
LIMK1_h |
Protein kinase |
Other |
LIMK |
|
AAC13884 |
AAC13884 |
258 |
7q11.23 (OMIM) |
|
|
216 |
LIMK2b_m |
M |
AB005132 |
AB005132 |
LIMK2b (2/23/99) LIMK2 isoform |
Protein kinase |
Other |
LIMK |
601aa LIMK2_h 95% |
BAA24489 |
BAA24489 |
617 |
M |
|
217 |
TESK2_h |
h |
AJ132545 |
AJ132545 |
TESK2, LIMK/TESK
family of protein kinases, predominantly expressed
in testis |
Protein kinase |
Other |
LIMK |
|
CAB41970 |
CAB41970 |
555 |
|
218 |
LKB1_h |
H |
U63333 |
U63333 |
PJK, LKB1, STK1, XEEK1_xl, Peutz
Jaeeger kinase |
Protein kinase |
Other |
LKB |
|
Q15831 |
Q15831 |
433 |
19p13.3 (OMIM) |
|
219 |
DLK_h |
H |
U07358 |
U07358 |
DLK_h, ZPK |
Protein kinase |
Other |
MLK |
|
AAA67343 |
AAA67343 |
859 |
12q13 (U) |
|
|
220 |
HH498 |
H |
AF116826 |
AF116826 |
HH498, AF116826, ankyrin repeats, MLK-
like |
Protein kinase |
Other |
MLK |
140aa C24A1.3_ce 45% |
AAD29632 |
AAD29632 |
835 |
|
221 |
MLK1_m |
M |
None |
NA |
MLK1_h (Mixed lineage kinase), JU0229 |
Protein kinase |
Other |
MLK |
|
P80192 |
P80192 |
394 |
14q24.3-14q31 (gene list) |
|
222 |
MLK2_h |
H |
X90846 |
X90846 |
MLK2, MST, I38044, S68178 |
Protein kinase |
Other |
MLK |
|
Q02779 |
Q02779 |
237 |
19q13.2 (ref Dorow) |
|
223 |
SPRK_h |
H |
L32976 |
L32976 |
SPRK, MLK3, PTK1, A53800 |
Protein kinase |
Other |
MLK |
|
AAA59859 |
AAA59859 |
847 |
11q13.1-11q13.3 (gene list) |
|
|
|
224 |
MOS_h |
H |
J00119 |
J00119 |
MOS_h |
Protein kinase |
Other |
MOS |
|
AAA52029 |
AAA52029 |
346 |
8q11 (OMIM) |
|
|
225 |
PIM2_h |
H |
U77735 |
U77735 |
PIM2_h
|
Protein kinase |
Other |
PIM |
|
AAC78506 |
AAC78506 |
334 |
Xp12-p21.1 (U) |
|
|
226 |
KID1_h |
H |
AA481701 |
AA481701 |
KID1_h |
Protein kinase |
Other |
PIM |
146aa KID1_r 97%
PIM1_h 82% |
BAA25182 |
BAA25182 |
605 |
22q13-2-qtel |
|
|
227 |
PIM1_h |
H |
M24779 |
M24779 |
PIM1_h |
Protein kinase |
Other |
PIM |
|
AAA81553 |
AAA81553 |
313 |
6p21.2 (gene list) |
|
228 |
PRK_h |
H |
U56998 |
U56998 |
PRK_h (FNK_m) |
Protein kinase |
Other |
PLK |
|
AAC50637 |
AAC50637 |
607 |
1p32.3-p31.1 (U) |
|
|
|
229 |
SNK_h |
H |
AA232799 |
AA232799 |
SNK_h ,
serum-inducible kinase |
Protein kinase |
Other |
PLK |
|
NP_006613 |
NP_006613 |
685 |
5q11.2 (U) |
|
|
|
230 |
PLK1_h |
H |
U01038 |
U01038 |
PLK1_h |
Protein kinase |
Other |
PLK |
|
AAA56634 |
AAA56634 |
603 |
NA |
|
|
231 |
SAK_h |
H |
Y13115 |
Y13115 |
SAK_h |
Protein kinase |
Other |
PLK |
|
CAA73575 |
CAA73575 |
970 |
4q26 (U) |
|
|
232 |
PRP4_h |
H |
AB011108 |
AB011108 |
PRP4h, KIAA0536,
sp|Q135351, pre-mRNA splicing kinase |
Protein kinase |
Other |
PRP4 |
799aa F22D6.5_ce 41%; PRP4_sp 43% |
BAA25462 |
BAA25462 |
1028 |
6ptel (U) |
|
233 |
KSR_h |
H |
U43586 |
U43586 |
KSR_h , kinase suppressor of Ras |
Protein kinase |
Other |
RAF |
|
AAC50354 |
AAC50354 |
635 |
NA |
|
|
234 |
ARaf_h |
H |
L24038 |
L24038 |
ARaf_h |
Protein kinase |
Other |
RAF |
|
AAA65219 |
AAA65219 |
606 |
Xp11.4-p11.2 |
|
|
235 |
BRaf_h |
H |
M95712 |
M95712 |
BRaf (417055, 323034) |
Protein kinase |
Other |
RAF |
|
AAA35609 |
AAA35609 |
765 |
7q34 (U) |
|
|
236 |
Raf1_h |
H |
X03484 |
X03484 |
Raf1_h |
Protein kinase |
Other |
RAF |
|
CAA27204 |
CAA27204 |
648 |
3p25.1 (G) |
|
|
237 |
RAF2psu_h |
H |
M11377 |
M11377 |
RAF2psu_h |
Protein kinase |
Other |
RAF |
239aa RAF1_h 66% |
psu |
psu |
|
|
|
238 |
HCYP2_r |
R |
AAD02059 |
AAD02059 |
homocysteine respondent protein HCYP2,
homocysteine-respondent gene cloned from WKY VSMCs |
Protein kinase |
Other |
RIP |
103/142 (72%) RIP3_h |
AF036537 |
AF036537 |
142 |
|
239 |
KIAA0472 |
H |
AB007941 |
AB007941 |
KIAA0472 |
Protein kinase |
Other |
RIP |
KIAA0472 100%; RIP_m 29% (Q60855); FES_h 30% (P07332) (CAT
domain) |
BAA32317 |
BAA32317 |
365 |
1q31 (U) |
|
240 |
RICK_h |
H |
NM_003821 |
NM_003821 |
RICK_h receptor-interacting serine-threonine
kinase 2 containing a caspase recruitment domain |
Protein kinase |
Other |
RIP |
170aa RICK_h 91% ;
RIP_h 37% |
NP_003812 |
NP_003812 |
540 |
M |
|
241 |
RIP_h |
H |
U50062 |
U50062 |
RIP_h |
Protein kinase |
Other |
RIP |
|
1236943 |
1236943 |
671 |
NA |
|
242 |
RIP3_h |
H |
AF156884 |
AF156884 |
RIP3, receptor-interacting protein 3 |
Protein kinase |
Other |
RIP |
|
AAD39005 |
AAD39005 |
518 |
|
243 |
SRPK2_h |
H |
NM_003138 |
NM_003138 |
SRPK2_h A
differentially expressed SR protein-specific
kinase, SFRS protein kinase 2 |
Protein kinase |
Other |
SRPK |
|
NP_003129 |
NP_003129 |
686 |
7q22.1 (U) |
|
|
|
244 |
MSSK1_h |
H |
AF027406 |
AF027406 |
muscle-specific serine kinase 1 |
Protein kinase |
Other |
SRPK |
360aa SRPK1_m 74%,135aa U52111_h 100%, SRPK1_h 70% |
AAD01848 |
AAD01848 |
533 |
Xq28 |
|
245 |
SRPK1_h |
H |
U09564 |
U09564 |
SRPK_h |
Protein kinase |
Other |
SRPK |
|
AAA20530 |
AAA20530 |
655 |
6p21.2 (gene list) |
|
246 |
ACTR-IIB4_h |
H |
X77533 |
X77533 |
ACVR2B, ACTR-IIB4_h |
Protein kinase |
Other |
STKR |
ACTR_IIB4_m 99%
ACTR_II_h 99% |
CAA54671 |
CAA54671 |
512 |
3p22-3p21.3 (gene list) |
|
247 |
ALK6_h |
H |
U89326 |
U89326 |
ALK6, Rpk1, R6 |
Protein kinase |
Other |
STKR |
|
AAC28131 |
AAC28131
|
502 |
4q22 (U) |
|
248 |
ACTR-II_h |
H |
M93415 |
M93415 |
ACTR-II_h |
Protein kinase |
Other |
STKR |
|
AAA35504 |
AAA35504 |
513 |
2q21.1-q21.2 (U) |
|
249 |
ALK1_h |
H |
A38805 |
A38805 |
ACVRL1, Activin like, Tsr-1, R3 |
Protein kinase |
Other |
STKR |
|
CAA02404 |
CAA02404 |
503 |
12q11-12q14 (gene list) |
|
|
250 |
ALK2_h |
H |
A38807 |
A38807 |
ALK2, ActR-1, Tsk7L, Skr1, R1 |
Protein kinase |
Other |
STKR |
|
2295238 |
2295238 |
509 |
2q22.3-q23.3 |
|
251 |
ALK3_h |
H |
Z22535 |
Z22535 |
ALK3, Brk-1, Tfr11, R5, Skr5, BMPR1A |
Protein kinase |
Other |
STKR |
|
CAA80257 |
CAA80257 |
532 |
10q22.3 (Locuslink) |
|
252 |
ALK4_h |
H |
Z22536 |
Z22536 |
ALK4, ActR-1B, R2, SKR2-1, SKR2-2 |
Protein kinase |
Other |
STKR |
|
CAA80258 |
CAA80258 |
505 |
12q11-13.2 (U) |
|
253 |
ALK5_h |
H |
L11695 |
L11695 |
TGFbetaR1, TbR-1, R4, RPK2 |
Protein kinase |
Other |
STKR |
|
AAA16073 |
AAA16073 |
503 |
9q33-9q34.1 (gene list) |
|
254 |
ALK7_r |
H |
U69702 |
U69702 |
ALK7, STKR6.22 |
Protein kinase |
Other |
STKR |
|
AAC52919 |
AAC52919 |
493 |
|
|
|
255 |
C14 |
R |
X71916 |
X71916 |
C14, MISIIR_r |
Protein kinase |
Other |
STKR |
|
CAA50731 |
CAA50731 |
557 |
R |
|
|
256 |
MISRII_h |
H |
U29700 |
U29700 |
MISRII_h |
Protein kinase |
Other |
STKR |
|
AAC50328 |
AAC50328 |
573 |
12q12-13.2 (U) |
|
257 |
T-ALK_h |
H |
Z48923 |
Z48923 |
T-ALK_h |
Protein kinase |
Other |
STKR |
|
CAA88759 |
CAA88759 |
1038 |
2q33-q34 (LocusLink) |
|
258 |
TGFbRII_h |
H |
D50683 |
D50683 |
TGFbRII_h |
Protein kinase |
Other |
STKR |
|
BAA09332 |
BAA09332 |
567 |
3pter-3p24.2 (gene list) |
|
259 |
TAK1_m |
M |
D76446 |
D76446 |
TAK1_m, (see AA314749_h) |
Protein kinase |
Other |
TAK1 |
|
BAA11184 |
BAA11184 |
597 |
NA |
|
|
260 |
TSK1_m |
M |
U01840 |
U01840 |
TSK1, tssk-1 |
Protein kinase |
Other |
TSK |
335aa TSK2_m 76% |
AAA99535 |
AAA99535 |
364 |
|
|
261 |
TSK2_h |
H |
L77564 |
L77564 |
TSK2_h, tssk-2, DGS-G; DiGeorge and
velo-cardio-facial syndrome |
Protein kinase |
Other |
TSK |
336aa TSK1_m 77% |
NA |
NA |
|
NA |
|
262 |
TSK3_m |
M |
AA060026 |
AA060026 |
TSK3_m - full-length |
Protein kinase |
Other |
TSK |
281aa TSK2_m 47% |
est |
est |
|
M |
|
263 |
TSK4_h |
H |
AA399669 |
AA399669 |
TSK4 |
Protein kinase |
Other |
TSK |
75aa TSK1-h 52% |
est |
est |
|
14p11.1-q11.1 (U) |
|
|
|
264 |
PKUa_h |
H |
AB004884 |
AB004884 |
PKUa_h
|
Protein kinase |
Other |
TSL |
PKUa_h (MTT) 100% TSL_at 60% |
BAA20561 |
BAA20561 |
719 |
17 (SHGC) |
|
265 |
TSL1_h |
H |
D50927 |
D50927 |
TSL1_h |
Protein kinase |
Other |
TSL |
|
BAA09486 |
BAA09486 |
549 |
2q24.1 (U) |
|
266 |
TTK_h |
H |
M86699 |
M86699 |
PYT, MPS1? |
Protein kinase |
Other |
TTK |
|
AAA61239 |
AAA61239 |
841 |
NA |
|
267 |
ULK1_h |
H |
NM_003565 |
NM_003565 |
ULK1 |
Protein kinase |
Other |
UNC |
1054aa ULK1_m 89%; KIAA0623_h 52%; UNC51_ce 43% |
NP_003556 |
NP_003556 |
1050 |
NA |
|
|
|
268 |
ULK2_h |
H |
AB014523 |
AB014523 |
KIAA0623_h, ULK2_m (UNC-51 like kinase) |
Protein kinase |
Other |
UNC |
110aa
KIAA0623_h 100% (92%na); ULK1_h 74%; |
BAA31598 |
BAA31598 |
1036 |
M |
|
269 |
VRK1_h |
H |
AB000449 |
AB000449 |
VRK1_h vaccinia related kinase 1, similarity to vaccinia virus B1R kinase |
Protein kinase |
Other |
VRK |
|
BAA19108 |
BAA19108 |
396 |
14q32 (gene list) |
|
|
|
270 |
51PK(L)_m |
M |
AF080253 |
AF080253 |
VRK1_m? 51PK(L), 51PK(S) |
Protein kinase |
Other |
VRK |
~100% 51PK(L)_m;
VRK1_h 87% (229bp 86%); VRK2_h
44% |
AAC29497 |
AAC29497 |
440 |
M |
|
|
271 |
VRK2_h |
H |
AB000450 |
AB000450 |
VRK2_h |
Protein kinase |
Other |
VRK |
273aa VRK2_h poor seq |
BAA19109 |
BAA19109 |
508 |
2p16-2p15 (gene list) |
|
|
|
272 |
MYT1_h |
H |
NM_004203 |
NM_004203 |
MYT1_h, membrane-associated tyrosine-
and threonine-specific cdc2-inhibitory kinase |
Protein kinase |
Other |
WEE |
MYT1_h 100% WEE1_h 59% |
NP_004194 |
NP_004194 |
499 |
NA |
|
|
|
273 |
AC004918 |
H |
AC004918 |
AC004918 |
similar to wee1-like protein kinase; PAC clone DJ0894A10 |
Protein kinase |
Other |
WEE |
|
AAD04726 |
AAD04726 |
541 |
|
274 |
WEE1_h |
H |
X62048 |
X62048 |
WEE1_h |
Protein kinase |
Other |
WEE |
|
CAA43979 |
CAA43979 |
646 |
11p15.3-p15.1 (OMIM) |
|
275 |
MPSK1_h |
H |
AF060798 |
AF060798 |
MPSK1, PKL12, PSK, EDPK, myristilated
and palmitylated STK |
Protein kinase |
Other |
YPL236_sc |
351aa YPL236c_sc 29%; GAK_h 29%; NEK1_m 28% |
AAC28337 |
AAC28337 |
305 |
3cen-3q21 (gene list) |
|
|
276 |
MPSK1psu_h |
H |
AA351147 |
AA351147 |
MPSK1psuedogene |
Protein kinase |
Other |
YPL236_sc |
257aa MPSK1_h 77% w mult frameshifts |
psu |
psu |
|
NA |
|
|
|
277 |
PKN_r |
R |
AB010154 |
AB010154 |
PKN_r C01C4.3 |
Protein kinase |
Other |
YWY3_ce |
|
BAA36362 |
BAA36362 |
417 |
|
|
278 |
NEK1_h |
H |
AL050385 |
AL050385 |
NEK1_h |
Protein kinase |
STE |
NEK |
223 aa NEK3_h P51956 58%; 250 aa NIMA_en P11837 37% |
AAD42879 |
AAD42879 |
771 |
NA |
|
|
279 |
NEK2_h |
H |
U11050 |
U11050 |
NEK2_h |
Protein kinase |
STE |
NEK |
310 aa NIMA_en (P11837) 40% |
AAA19558 |
AAA19558 |
445 |
1q31-32.1 (U) |
|
280 |
NEK3_h |
H |
Z29067 |
Z29067 |
NEK3_h, NIMA-related kinase NEK3 |
Protein kinase |
STE |
NEK |
336/458 (73%) NEK3_m; 265 aa NEK1_m (P51954) 42% |
P51956 |
P51956 |
459 |
13q14.3 (U) |
|
|
281 |
NEK3a_m |
M |
AAD20986 |
AAD20986 |
NIMA-related kinase NEK3. March 99 |
Protein kinase |
STE |
NEK |
336/458 (73%) NEK3_h |
AF093416 |
AF093416 |
511 |
|
|
282 |
NEK4_h |
H |
SUGEN |
SUGEN |
NEK4_h; NEK4a,b;
HPK1_incyte (WO98/11234) |
Protein kinase |
STE |
NEK |
235
aa F19H6.1_ce 73%; 244 aa NEK1_m
(P51954) 39% |
SUGEN |
SUGEN |
|
9q31-q32 (U) |
|
|
283 |
NEK5_h |
H |
SUGEN |
SUGEN |
NEK5_h |
Protein kinase |
STE |
NEK |
256 aa NEK1_m (P51954) 37%
|
SUGEN |
SUGEN |
|
NA |
|
|
|
284 |
NEK6_h |
H |
AB028971 |
AB028971 |
NEK6_h |
Protein kinase |
STE |
NEK |
207aa
AF052296_dm 68%; F35G12.3b _ce 44%; 292aa GAK_h 40% |
BAA83000 |
BAA83000 |
863 |
NA |
|
|
|
285 |
NRK2_h |
H |
L20321 |
L20321 |
NRK2_h, STK2, MSTK2_m, NEK4_m
(AF099067.1) |
Protein kinase |
STE |
NEK |
|
NP_003148 |
NP_003148 |
841 |
3p21.1 (gene list) |
|
286 |
MEKK3_h |
H |
U78876 |
U78876 |
MEKK3_h |
Protein kinase |
STE |
STE11 |
|
AAB41729 |
AAB41729 |
626 |
NA |
|
287 |
MEKK4a _h |
H |
AF002715 |
AF002715 |
MEKK4a _h, MTK1,
KIAA0213 Similar to TFIIi-associated
transactivator factor |
Protein kinase |
STE |
STE11 |
|
AAB68804 |
AAB68804 |
1607 |
6 (OMIM) |
|
288 |
MEKK5_h |
H |
U67156 |
U67156 |
MEKK5, ASK, MAPKKK5_h |
Protein kinase |
STE |
STE11 |
|
AAC50894 |
AAC50894 |
1374 |
6q22.33 (gene list) |
|
289 |
NIK_h |
H |
Y10256 |
Y10256 |
NIK_h, NF-kappaB inducing kinas, MAP3K-related
kinase involved in NF-kappaB induction by TNF, CD95 and IL-1, NIK_m
(AF143094.1) |
Protein kinase |
STE |
STE11 |
|
CAA71306 |
CAA71306 |
947 |
17p21.1 (U) |
|
|
290 |
MEKK1_h |
H |
AF042838 |
AF042838 |
MEKK1_h |
Protein kinase |
STE |
STE11 |
|
AAC97073 |
AAC97073 |
1495 |
5 (gene list) |
|
291 |
MEKK2_m |
M |
U43186 |
U43186 |
MEKK2_m |
Protein kinase |
STE |
STE11 |
288aa MEK2_m 83%, 930bp 91% |
AAB03536 |
AAB03536 |
619 |
M |
|
292 |
MEKK6 |
H |
AF100318 |
AF100318 |
MEKK6_h,
ASK2_m apoptosis signal-regulating kinase 2 |
Protein kinase |
STE |
STE11 |
|
NP_004663 |
NP_004663 |
1011 |
|
293 |
YSK4_m |
M |
U49951 |
U49951 |
YSK4_m |
Protein kinase |
STE |
STE11 |
65aa - MEKK3_h
46.2%; 40.7% |
AAB61531 |
AAB61531 |
65 |
M |
|
294 |
MST3_h |
H |
AF024636 |
AF024636 |
MST3, STLK1 |
Protein kinase |
STE |
STE20-01 |
MST3_h 100% STE20_h 89% |
AAB82560 |
AAB82560 |
431 |
13q32.1-22 |
|
295 |
STE20_h |
H |
D63780 |
D63780 |
YSK1, SOK |
Protein kinase |
STE |
STE20-01 |
|
BAA20420 |
BAA20420 |
426 |
2q34-37.2 (U) |
|
296 |
STLK2 |
H |
SUGEN |
SUGEN |
STLK2, (STE20-like kinase2) |
Protein kinase |
STE |
STE20-01 |
|
SUGEN |
SUGEN |
|
Xq25-27.1 |
|
297 |
STLK3 |
H |
AF099989 |
AF099989 |
STLK3, PASK_r, SPAK_m (AF099988) |
Protein kinase |
STE |
STE20-01 |
|
AAC72238 |
AAC72238 |
547 |
|
|
|
298 |
STLK4 |
H |
SUGEN |
SUGEN |
STLK4, (STE20-like kinase4) |
Protein kinase |
STE |
STE20-01 |
|
SUGEN |
SUGEN |
|
|
|
299 |
STLK5 |
H |
SUGEN |
SUGEN |
STLK5, (STE20-like kinase5) |
Protein kinase |
STE |
STE20-01 |
|
SUGEN |
SUGEN |
|
17q23.2-24.2 |
|
300 |
STLK6_h |
H |
SUGEN |
SUGEN |
STLK6_h, (STE20-like kinase6) |
Protein kinase |
STE |
STE20-01 |
243aa STLK5_h 50% |
SUGEN |
SUGEN |
|
2q32.2-q33.3 |
|
|
|
301 |
STLK7_h |
H |
SUGEN |
SUGEN |
STLK7_h, (STE20-like kinase7) |
Protein kinase |
STE |
STE20-01 |
102aa STLK3_h=SPAK_h (AF099989) 86% (311bp 75%) |
SUGEN |
SUGEN |
|
NA |
|
|
302 |
PAK1_h |
H |
U24152 |
U24152 |
PAK1, PAK-A_m, alpha-PAK, p65-PAK,
MUK2_r, p68PAK |
Protein kinase |
STE |
STE20-02 |
|
AAA65441 |
AAA65441 |
545 |
11q13-11q14 (gene list) |
|
|
303 |
PAK2_h |
H |
U24153 |
U24153 |
PAK2, p65-PAK |
Protein kinase |
STE |
STE20-02 |
|
AAA65442 |
AAA65442 |
525 |
NA |
|
|
|
304 |
PAK3_h |
H |
R26396 |
R26396 |
PAK3, bPAK, PAK65, Gamma-PAK,
p21-activated kinase3 |
Protein kinase |
STE |
STE20-02 |
hPAK65 _h 95% |
AAC36097 |
AAC36097 |
544 |
Xq21.3-q24 (OMIM) |
|
|
305 |
PAK4_h |
H |
SUGEN |
SUGEN |
PAK4 |
Protein kinase |
STE |
STE20-02 |
|
SUGEN |
SUGEN |
|
|
|
306 |
PAK5_h |
H |
AJ011855 |
AJ011855 |
PAK5 |
Protein kinase |
STE |
STE20-02 |
|
CAA09820 |
CAA09820 |
591 |
|
|
|
307 |
PAK6_h |
H |
AL031652 |
AL031652 |
PAK6 Genomic clones |
Protein kinase |
STE |
STE20-02 |
136aa PAK5 81%, PAK4_h 74%, PAK3_h 53% |
CAA21067 |
CAA21067 |
138 |
|
|
|
308 |
ZC1_h |
H |
NM_004834 |
NM_004834.1 |
ZC1, NIK_m, HPK/GCK-like, KIAA0687 |
Protein kinase |
STE |
STE20-03 |
|
NP_004825 |
NP_004825 |
1165/1239 |
|
|
309 |
ZC2_h |
H |
AB011123 |
AB011123 |
ZC2, KIAA0551 |
Protein kinase |
STE |
STE20-03 |
|
BAA25477 |
BAA25477 |
1333/1297 |
|
|
|
310 |
ZC3_h |
H |
SUGEN |
SUGEN |
ZC3 |
Protein kinase |
STE |
STE20-03 |
|
SUGEN |
SUGEN |
1326 |
|
311 |
ZC4_h |
H |
SUGEN |
SUGEN |
ZC4 |
Protein kinase |
STE |
STE20-03 |
|
SUGEN |
SUGEN |
|
Xq22 |
|
312 |
HPK1_h |
H |
U66464 |
U66464 |
HPK1_h
|
Protein kinase |
STE |
STE20-04 |
|
AAB97983 |
AAB97983 |
833 |
|
313 |
BL44_h |
H |
U07349 |
U07349 |
BL44, GCK, Rab8 interacting protein |
Protein kinase |
STE |
STE20-04 |
|
AAA20968 |
AAA20968 |
819 |
11q13 (OMIM) |
|
314 |
KHS1_h |
H |
U77129 |
U77129 |
KHS1_h, kinase homologous to SPS1/STE20 |
Protein kinase |
STE |
STE20-04 |
|
AAB48435 |
AAB48435 |
846 |
|
|
315 |
KHS2_h |
H |
NM_003618 |
NM_003618 |
KHS2_h, RAB8IPL1 (rab8 interacting
protein-like 1) |
Protein kinase |
STE |
STE20-04 |
|
NP_003609 |
NP_003609 |
884 |
|
|
316 |
GEK2_h |
H |
NM_005990 |
NM_005990 |
GEK2_h, GEK1_m, LOK, PLKK1_xl |
Protein kinase |
STE |
STE20-05 |
|
NP_005981 |
NP_005981 |
968 |
NA 11/98 |
|
|
317 |
SLK_h |
H |
D86959 |
D86959 |
SLK_h |
Protein kinase |
STE |
STE20-05 |
253aa SLK_h KIAA0204_h |
BAA13195 |
BAA13195 |
1152 |
16p13.3 |
|
318 |
SULU1_h |
H |
SUGEN |
SUGEN |
SULU1 |
Protein kinase |
STE |
STE20-06 |
|
SUGEN |
SUGEN |
|
319 |
SULU2_h |
H |
AB020288 |
AB020288 |
KIAA0881_h, TAO2_r, SULU2, protate-derived
STE20-like kinase PSK |
Protein kinase |
STE |
STE20-06 |
1050aa SULU3_h 70%; 921aa SULU1 64%, 970aa SULU_ce 37% |
BAA74904 |
BAA74904 |
1049 |
|
320 |
SULU3_r |
H |
AF084205 |
AF084205 |
SULU3, TAO1_r |
Protein kinase |
STE |
STE20-06 |
|
AAC71014 |
AAC71014 |
1001 |
17p11.2 (gene list) |
|
321 |
MST1_h |
H |
U60207 |
U60207 |
MST1, KRS-2 |
Protein kinase |
STE |
STE20-07 |
|
AAB17262 |
AAB17262 |
487 |
19q13.1-q13.2 (Ref
Katoh) |
|
322 |
MST2_h |
H |
U26424 |
U26424 |
MST2_h |
Protein kinase |
STE |
STE20-07 |
|
AAC50386 |
AAC50386 |
491 |
8q21.3-q23 (U) |
|
|
|
323 |
CDC7_h |
H |
AF015592 |
AF015592 |
CDC7_h |
Protein kinase |
STE |
STE20-08 |
|
AAC52080 |
AAC52080 |
574 |
1q12-1p13.3 (U) |
|
|
|
324 |
MEK1_h |
H |
L11284 |
L11284 |
MEK1, MKK1, MAPKK1 |
Protein kinase |
STE |
STE7 |
|
NP_002746 |
NP_002746 |
393 |
15q22.1-q22.33 (OMIM) |
|
325 |
MEK2_h |
H |
AI193527 |
AI193527 |
MEK2 |
Protein kinase |
STE |
STE7 |
501bp MEK2_h 98% |
P36507 |
P36507 |
400 |
|
|
326 |
MEK5_h |
H |
U25265 |
U25265 |
MEK5_h |
Protein kinase |
STE |
STE7 |
|
AAA96146 |
AAA96146 |
438 |
NA |
|
|
327 |
MEK6_h |
H |
U39657 |
U39657 |
MEK6, MKK6, SAPKK3 |
Protein kinase |
STE |
STE7 |
|
AAC50389 |
AAC50389 |
334 |
17q22 (U) |
|
|
328 |
MKK3_h |
H |
U66839 |
U66839 |
MKK3, MEK3 |
Protein kinase |
STE |
STE7 |
|
AAB40652 |
AAB40652 |
347 |
17q11.2 (OMIM) |
|
|
|
329 |
MKK7a_h |
H |
AF022805 |
AF022805 |
MKK7a , SAPKK4,
SAPKK5, JNKK2 |
Protein kinase |
STE |
STE7 |
|
AAC26142 |
AAC26142 |
419 |
19ptel (U) |
|
|
|
330 |
MPK3b_h |
H |
U66839 |
U66839 |
MKK3, MPK3, MAPKK3b, SAPKK2 |
Protein kinase |
STE |
STE7 |
334aa MPK6_h 80%; MPK4_h 49% |
P46734 |
P46734 |
347 |
NA |
|
|
|
331 |
MPK4_h |
H |
L36870 |
L36870 |
MPK4, MKK4, SEK1, MEK4, JNKK, SAPKK1 |
Protein kinase |
STE |
STE7 |
|
AAC41719 |
AAC41719 |
399 |
17p11.2 (gene list) |
|
332 |
BLK_h |
H |
S76617 |
S76617 |
B lymphoid Tyr kin |
Protein kinase |
TK |
CTK-01 |
|
AAB33265 |
AAB33265 |
505 |
8p23-8p22 (gene list) |
|
|
333 |
FGR_h |
H |
M19722 |
M19722 |
FGR_h |
Protein kinase |
TK |
CTK-01 |
|
AAA52451 |
AAA52451 |
529 |
1p36.1-36.2 |
|
334 |
FYN_h |
H |
M14333 |
M14333 |
FYN, Slk, Syn |
Protein kinase |
TK |
CTK-01 |
|
NP_002028 |
NP_002028 |
537 |
6q21 (OMIM) |
|
335 |
HCK_h |
H |
NM_002110 |
NM_002110 |
HCK, Bmk |
Protein kinase |
TK |
CTK-01 |
|
P08631 |
P08631 |
526 |
20q11-20q12 (gene list) |
|
|
336 |
LCK_h |
H |
X13529 |
X13529 |
LCK, Tkl |
Protein kinase |
TK |
CTK-01 |
|
P06239 |
P06239 |
509 |
1p35-1p34.3 (gene list) |
|
|
337 |
LYN_h |
H |
M16038 |
M16038 |
LYN_h |
Protein kinase |
TK |
CTK-01 |
|
NP_002341 |
NP_002341 |
513 |
8q11-12 (ref, corey) |
|
338 |
SRC_h |
H |
NM_005417 |
NM_005417 |
SRC_h |
Protein kinase |
TK |
CTK-01 |
|
P12931 |
P12931 |
543 |
20q11.2-q13 (MIM) |
|
339 |
YES_h |
H |
M15990 |
M15990 |
YES_h |
Protein kinase |
TK |
CTK-01 |
|
AAA35735 |
AAA35735 |
543 |
18p11.3 (OMIM) (pseudo CHR 22) |
|
340 |
FERpsu_h |
H |
H63831 |
H63831 |
FER pseudogene, SuCTK04 |
Protein kinase |
TK |
CTK-01p |
73aa FER_m 72% |
psu |
psu |
|
pseudo |
|
|
341 |
FYNpsu_h |
M |
W49330 |
W49330 |
FYN pseudo |
Protein kinase |
TK |
CTK-01p |
184aa - FYN_h
62.7%; 62.8%; |
psu |
psu |
|
M |
|
|
342 |
BRK_h |
H |
X78549 |
X78549 |
BRK, Cck3, PTK6 |
Protein kinase |
TK |
CTK-02 |
|
CAA55295 |
CAA55295 |
451 |
NA |
|
343 |
FRK_h |
H |
U00803 |
U00803 |
FRK, MKK3, Tk1, Rak, IYK_m, BSK_m,
GTK_r |
Protein kinase |
TK |
CTK-02 |
|
NP_002022 |
NP_002022 |
505 |
NA |
|
344 |
SAD_h |
H |
SUGEN |
SUGEN |
SAD_h |
Protein kinase |
TK |
CTK-02 |
|
SUGEN |
SUGEN |
|
NA |
|
345 |
SRM_m |
M |
D49427 |
D49427 |
SRM |
Protein kinase |
TK |
CTK-02 |
|
Q62270 |
Q62270 |
496 |
|
346 |
TXK_h |
H |
L27071 |
L27071 |
TXK, Rlk |
Protein kinase |
TK |
CTK-03 |
257aa TXK_h 100% TXK_m
88%; TEC_m 68% |
AAA74557 |
AAA74557 |
527 |
4p12 (gene list) |
|
347 |
BMX_h |
H |
X83107 |
X83107 |
Bmx, MKK2 |
Protein kinase |
TK |
CTK-03 |
|
CAA58169 |
CAA58169 |
675 |
Xp22.2 (gene list) |
|
348 |
BTK_h |
H |
X58957 |
X58957 |
BTK, Atk, Bpk, Bruton agammaglobulinemia |
Protein kinase |
TK |
CTK-03 |
|
Q06187 |
Q06187 |
659 |
Xq21.33-q22 (gene list) |
|
|
|
349 |
ITK_h |
H |
L10717 |
L10717 |
ITK, Lyk, Tsk, Emt, IL2-inducible T-cell kinase |
Protein kinase |
TK |
CTK-03 |
|
NP_005537 |
NP_005537 |
620 |
5q31-5q32 |
|
350 |
TEC_h |
H |
D29767 |
D29767 |
TEC_h |
Protein kinase |
TK |
CTK-03 |
|
NP_003206 |
NP_003206 |
631 |
4p12 (gene list) |
|
351 |
CSK_h |
H |
X74765 |
X74765 |
CSK |
Protein kinase |
TK |
CTK-04 |
|
P41240 |
P41240 |
450 |
15q23-q25 (LocusLink) |
|
352 |
CTK_h |
H |
L18974 |
L18974 |
CTK, Mkk1, MATK, Hyl, Lsk, Ntk |
Protein kinase |
TK |
CTK-04 |
|
P42679 |
P42679 |
505 |
19p13.3 (gene list) |
|
353 |
ABL_h |
H |
X16416 |
X16416 |
ABL_h |
Protein kinase |
TK |
CTK-05 |
|
P00519 |
P00519 |
1130 |
|
|
354 |
ARG_h |
H |
M35296 |
M35296 |
ARG_h |
Protein kinase |
TK |
CTK-05 |
|
NP_005149 |
NP_005149 |
1182 |
1q24-q25 (OMIM) |
|
|
355 |
SYK_h |
H |
L28824 |
L28824 |
SYK, spleen tyr kinase |
Protein kinase |
TK |
CTK-06 |
|
P43405 |
P43405 |
635 |
9q22 (gene list) |
|
|
356 |
ZAP70_h |
H |
L05148 |
L05148 |
ZAP70_h |
Protein kinase |
TK |
CTK-06 |
|
P43403 |
P43403 |
619 |
2q11-2q13 (gene list) |
|
|
357 |
FER_h |
H |
J03358 |
J03358 |
FER, Flk |
Protein kinase |
TK |
CTK-07 |
|
NP_005237 |
NP_005237 |
822 |
5q12-21 (gene list) |
|
|
358 |
FES_h |
H |
X52192 |
X52192 |
FES, FPS |
Protein kinase |
TK |
CTK-07 |
|
P07332 |
P07332 |
822 |
15q26.1 (OMIM) |
|
359 |
FAK_h |
H |
L13616 |
L13616 |
PTK2 |
Protein kinase |
TK |
CTK-08 |
|
Q05397 |
Q05397 |
1052 |
8q24 (OMIM) |
|
|
|
360 |
PYK2_h |
H |
U43522 |
U43522 |
FAK2, CAKb, RAFTK, PTK2B |
Protein kinase |
TK |
CTK-08 |
|
NP_004094 |
NP_004094 |
1009 |
8p21.1 (gene list) |
|
|
|
361 |
JAK1_h |
H |
M64174 |
M64174 |
JAK1_h |
Protein kinase |
TK |
CTK-09 |
|
NP_002218 |
NP_002218 |
1142 |
1p32.3-1p31.3 (gene list) |
|
362 |
JAK2_h |
H |
AF005216 |
AF005216 |
JAK2_h |
Protein kinase |
TK |
CTK-09 |
|
NP_004963 |
NP_004963 |
1132 |
9p24 (gene list) |
|
363 |
JAK3_h |
H |
U09607 |
U09607 |
JAK3_h |
Protein kinase |
TK |
CTK-09 |
|
NP_000206 |
NP_000206 |
1124 |
19p13.1 (gene list) |
|
364 |
TYK2_h |
H |
X54637 |
X54637 |
TYK2_h |
Protein kinase |
TK |
CTK-09 |
|
NP_003322 |
NP_003322 |
1187 |
19p13.2 (gene list) |
|
|
|
365 |
ACK_h |
H |
L13738 |
L13738 |
ACK, Pyk1 |
Protein kinase |
TK |
CTK-10 |
|
NP_005772 |
NP_005772 |
1091 |
|
|
|
366 |
TNK1_h |
H |
U43408 |
U43408 |
TNK1_h, ACK2 |
Protein kinase |
TK |
CTK-10 |
|
AAC50427 |
AAC50427 |
666 |
NA |
|
367 |
EGFR_h |
H |
X00588 |
X00588 |
EGFR, ErbB |
Protein kinase |
TK |
RTK-01 |
|
NP_005219 |
NP_005219 |
1210 |
7p12.3-p12.1 (OMIM) |
|
368 |
HER2_h |
H |
M11730 |
M11730 |
HER2, ErbB2 |
Protein kinase |
TK |
RTK-01 |
|
NP_004439 |
NP_004439 |
1255 |
17q21.2 (OMIM) |
|
369 |
HER3_h |
H |
M34309 |
M34309 |
HER3, ErbB3 |
Protein kinase |
TK |
RTK-01 |
|
NP_001973 |
NP_001973 |
1342 |
12q13 (Entrez) |
|
|
370 |
HER4_h |
H |
L07868 |
L07868 |
HER4, ErbB4 |
Protein kinase |
TK |
RTK-01 |
|
NP_005226 |
NP_005226 |
1308 |
2q33.3-q34 (OMIM) |
|
371 |
IGF1R_h |
H |
X04434 |
X04434 |
IGF1R_h |
Protein kinase |
TK |
RTK-02 |
|
NP_000866 |
NP_000866 |
1367 |
15q25-q26 (OMIM) |
|
372 |
INSR_h |
H |
X02160 |
X02160 |
INSR_h |
Protein kinase |
TK |
RTK-02 |
|
P06213 |
P06213 |
1382 |
19p13.2 (OMIM) |
|
373 |
IRR_h |
H |
J05046 |
J05046 |
IRR_h |
Protein kinase |
TK |
RTK-02 |
|
P14616 |
P14616 |
1268 |
Chr.1 (OMIM) |
|
374 |
CSFR_h |
H |
X03663 |
X03663 |
CSFR_h |
Protein kinase |
TK |
RTK-03 |
|
P07333 |
P07333 |
972 |
5q33.2-q33.3 (U) |
|
375 |
KIT_h |
H |
X06182 |
X06182 |
KIT_h |
Protein kinase |
TK |
RTK-03 |
|
NP_000213 |
NP_000213 |
976 |
4q12 (U) |
|
376 |
PDGFRa_h |
H |
NM_006206 |
NM_006206 |
PDGFRa_h |
Protein kinase |
TK |
RTK-03 |
|
NP_006197 |
NP_006197 |
1089 |
Chr.11, D11S1357-D11S1765 |
|
377 |
PDGFRb_h |
H |
J03278 |
J03278 |
PDGFRb_h |
Protein kinase |
TK |
RTK-03 |
|
NP_002600 |
NP_002600 |
1106 |
5q31-q32 (U) |
|
|
378 |
FLK2_h |
H |
NM_004119 |
NM_004119 |
FLK2, Flt3, STK1 |
Protein kinase |
TK |
RTK-04 |
|
NP_004110 |
NP_004110 |
993 |
M |
|
379 |
FLT1_h |
H |
X51602 |
X51602 |
FLT1_h |
Protein kinase |
TK |
RTK-04 |
|
NP_002010 |
NP_002010 |
1338 |
13q12 (gene list) |
|
380 |
FLT4_h |
H |
X68203 |
X68203 |
FLT4_h |
Protein kinase |
TK |
RTK-04 |
|
P35916 |
P35916 |
1298 |
5q34-5q35 (gene list) |
|
|
381 |
KDR_h |
H |
AF035121 |
AF035121 |
KDR, FLK1, NYK |
Protein kinase |
TK |
RTK-04 |
|
AAB88005 |
AAB88005 |
1356 |
4q12 (gene list) |
|
382 |
FGFR1_h |
H |
M60485 |
M60485 |
FGFR1, FLG, CEK1 |
Protein kinase |
TK |
RTK-05 |
|
P11362 |
P11362 |
822 |
8p11.2-8p11.1 (gene list) |
|
|
383 |
FGFR2_h |
H |
M87770 |
M87770 |
FGFR2, BEK, KSAM, KSAMI, Cek3 |
Protein kinase |
TK |
RTK-05 |
|
NP_000132 |
NP_000132 |
821 |
10q25.3-10q26 (gene list) |
|
384 |
FGFR3_h |
H |
M58051 |
M58051 |
FGFR3, CEK2 |
Protein kinase |
TK |
RTK-05 |
|
NP_000133 |
NP_000133 |
806 |
4p16.3 (gene list) |
|
385 |
FGFR4_h |
H |
L03840 |
L03840 |
FGFR4_h |
Protein kinase |
TK |
RTK-05 |
|
NP_002002 |
NP_002002 |
802 |
5q35.1-5qter (gene list) |
|
386 |
FGFR3pse_m |
M |
U52463 |
U52463 |
FGFR3pseudo_m |
Protein kinase |
TK |
RTK-05p |
266aa
- FGFR3_h 66%; |
psu |
psu |
|
M |
|
|
|
387 |
CCK4_h |
H |
U33635 |
U33635 |
CCK4, KLG |
Protein kinase |
TK |
RTK-06 |
|
AAA87565 |
AAA87565 |
1070 |
6p21.1-p12.2 |
|
388 |
MET_h |
H |
NM_000245 |
NM_000245 |
MET_h |
Protein kinase |
TK |
RTK-07 |
|
NP_000236 |
NP_000236 |
1408 |
7q31 (OMIM) |
|
389 |
RON_h |
H |
X70040 |
X70040 |
RON, MST1R, CCK1, MDK3 |
Protein kinase |
TK |
RTK-07 |
|
NP_002438 |
NP_002438 |
1400 |
3p21.3 (gene list) |
|
390 |
TRKA_h |
H |
M23102 |
M23102 |
NTRK1 |
Protein kinase |
TK |
RTK-08 |
|
NP_002520 |
NP_002520 |
796 |
1q21-1q22 (gene list) |
|
|
|
391 |
TRKB_h |
H |
U12140 |
U12140 |
TRKB |
Protein kinase |
TK |
RTK-08 |
|
NP_006171 |
NP_006171 |
822 |
9q22.1 (gene list) |
|
392 |
TRKC_h |
H |
U05012 |
U05012 |
TRKC_h |
Protein kinase |
TK |
RTK-08 |
|
NP_002521 |
NP_002521 |
825 |
15q24-15q25 (gene list) |
|
393 |
MER_h |
H |
U08023 |
U08023 |
MER, TYRO12, c-ryk, EYK?? |
Protein kinase |
TK |
RTK-09 |
|
NP_006334 |
NP_006334 |
999 |
2q12 (U) |
|
|
394 |
AXL_h |
H |
M76125 |
M76125 |
AXL, ARK, UFO |
Protein kinase |
TK |
RTK-09 |
|
NP_001690 |
NP_001690 |
885 |
19q13.1 (gene list) |
|
395 |
TYRO3_h |
H |
U18934 |
U18934 |
TYRO3, Sky, Rse, Tif, Brt, DTK |
Protein kinase |
TK |
RTK-09 |
|
NP_006284 |
NP_006284 |
882 |
15q15.1-15q21.1 (gene list) |
|
396 |
ZPK_h |
H |
L08961 |
L08961 |
ZPK_h |
Protein kinase |
TK |
RTK-09 |
|
AAC41766 |
AAC41766 |
600 |
L08961 = c-mer |
|
397 |
Tyro3psu_h |
H |
X72887 |
X72887 |
Tyro3psu_h |
Protein kinase |
TK |
RTK-09p |
274aa Tyro3_h 86% |
psu |
psu |
|
NA |
|
398 |
TEK_h |
H |
L06139 |
L06139 |
TEK, TIE2, HPK-6 |
Protein kinase |
TK |
RTK-10 |
|
NP_000450 |
NP_000450 |
1124 |
9p21 (gene list) |
|
399 |
TIE_h |
H |
X60957 |
X60957 |
TIE_h |
Protein kinase |
TK |
RTK-10 |
|
NP_005415 |
NP_005415 |
1138 |
1p34-p33 (OMIM) |
|
400 |
EphA1_h |
H |
M18391 |
M18391 |
EphA1, Eph, Esk |
Protein kinase |
TK |
RTK-11 |
|
NP_005223 |
NP_005223 |
984 |
7q32-7q36 (gene list) |
|
401 |
EphA2_h |
H |
M59371 |
M59371 |
EphA2, Eck, Myk2, Sek2 |
Protein kinase |
TK |
RTK-11 |
|
NP_004422 |
NP_004422 |
976 |
1p36.1 (gene list) |
|
402 |
EphA3_h |
H |
M83941 |
M83941 |
EphA3, Cek4, Mek4, Hek, Tyro4, Hek4 |
Protein kinase |
TK |
RTK-11 |
|
NP_005224 |
NP_005224 |
983 |
3p11.2 (gene list) |
|
403 |
EphA4_h |
H |
L36645 |
L36645 |
EphA4, Sek, Sek1, Cek8, Hek8, Tyro1 |
Protein kinase |
TK |
RTK-11 |
|
NP_004429 |
NP_004429 |
986 |
NA |
|
404 |
EphA5_h |
H |
X95425 |
X95425 |
EphA5, Ehk1, Bsk, Cek7, Hek7, Rek7 |
Protein kinase |
TK |
RTK-11 |
|
P54756 |
P54756 |
1037 |
NA |
|
405 |
EphA6_m |
M |
U58332 |
U58332 |
EphA6, Ehk2,Hek12 |
Protein kinase |
TK |
RTK-11 |
314aa - EphA7_h 71.0% |
Q62413 |
Q62413 |
1035_m |
M |
|
406 |
EphA7_h |
H |
L36642 |
L36642 |
EphA7, Mdk1, Hek11, Ehk3, Ebk, Cek11 |
Protein kinase |
TK |
RTK-11 |
|
NP_004431 |
NP_004431 |
998 |
6q14-15 (U) |
|
|
407 |
EphA8_m |
M |
U72207 |
U72207 |
EphA8, Eek, Hek3 |
Protein kinase |
TK |
RTK-11 |
260aa EphA7_h 74.1% |
O09127 |
O09127 |
1004_m |
1 (gene list) |
|
|
408 |
EphB1_h |
H |
L40636 |
L40636 |
EphB1, Elk, Cek6, Net, Hek6 |
Protein kinase |
TK |
RTK-11 |
|
NP_004432 |
NP_004432 |
984 |
3q21-3q23 (gene list) |
|
|
409 |
EphB2_h |
H |
AF025304 |
AF025304 |
EphB2, Cek5, Nuk, Erk, Qek5, Tyro5,
Sek3, Hek5, Drt |
Protein kinase |
TK |
RTK-11 |
|
NP_004433 |
NP_004433 |
987 |
1p36.1 (gene list) |
|
|
410 |
EphB3_h |
H |
X75208 |
X75208 |
EphB3, Cek10, Hek2, Mdk5, Tyro6, Sek4 |
Protein kinase |
TK |
RTK-11 |
|
NP_004434 |
NP_004434 |
998 |
3q21-3qter (gene list) |
|
|
411 |
EphB4_h |
H |
U07695 |
U07695 |
EphB4, Htk, Myk1, Tyro11, Mdk2 |
Protein kinase |
TK |
RTK-11 |
|
NP_004435 |
NP_004435 |
987 |
7 (gene list) |
|
|
412 |
EphB5_c |
C |
U23783 |
U23783 |
EphB5, Cek9, Hek9 |
Protein kinase |
TK |
RTK-11 |
|
Q07497 |
Q07497 |
1002 |
C |
|
|
413 |
EphB6_h |
H |
NM_004445 |
NM_004445 |
EphB6, Mep |
Protein kinase |
TK |
RTK-11 |
|
NP_004436 |
NP_004436 |
1006 |
7q33-7q35 (gene list) |
|
|
414 |
RYK_h |
H |
S59184 |
S59184 |
RYK, Vik, Nykr |
Protein kinase |
TK |
RTK-12 |
|
P34925 |
P34925 |
604 |
3q22 (gene list) |
|
|
415 |
DDR_h |
H |
Z29093 |
Z29093 |
DDR, MCK10, Cak, Nep, MPK-6 |
Protein kinase |
TK |
RTK-13 |
|
Q08345 |
Q08345 |
913 |
6p21.3 (OMIM) or 6q16
(LocusLink) |
|
416 |
RTK40 |
R |
AAD01584 |
AAD01584 |
RTK40 homolog, tyro10 |
Protein kinase |
TK |
RTK-13 |
137/155 (88%) TYRO10_m; 660/726 (90%) |
AF016247 |
AF016247 |
168 |
|
|
|
417 |
TYRO10_h |
H |
X74764 |
X74764 |
TYRO10, DDR2, Tkt, Cck2 |
Protein kinase |
TK |
RTK-13 |
|
NP_006173 |
NP_006173 |
855 |
1q21-1q23 (gene list) |
|
|
418 |
ROS_h |
H |
M34353 |
M34353 |
ROS_h |
Protein kinase |
TK |
RTK-14 |
|
NP_002935 |
NP_002935 |
2347 |
6q22 (U) |
|
|
419 |
RET_h |
H |
M57464 |
M57464 |
RET_h |
Protein kinase |
TK |
RTK-15 |
|
P07949 |
P07949 |
1114 |
10q11.2 (OMIM) |
|
420 |
ALK_h |
H |
U62540 |
U62540 |
Anaplastic lymphoma kinase |
Protein kinase |
TK |
RTK-16 |
|
NP_004295 |
NP_004295 |
1620 |
2p23 (gene list) |
|
421 |
LTK_h |
H |
D16105 |
D16105 |
LTK_h |
Protein kinase |
TK |
RTK-16 |
|
P29376 |
P29376 |
864 |
15q15.1-15q15.2 (gene list) |
|
422 |
ROR1_h |
H |
M97675 |
M97675 |
ROR1_h, neurotrophic tyrosine kinase,
receptor-related 1 |
Protein kinase |
TK |
RTK-17 |
|
NP_005003 |
NP_005003 |
937 |
Conflict: Transcript
map: D11S2301E , Chr.11, D11S1357-D11S913
& SHGC-9888 , Chr.1,
D1S515-D1S2866 (both U) |
|
423 |
ROR2_h |
H |
M97639 |
M97639 |
ROR2_h, NTRKR2, neurotrophic tyrosine
kinase, receptor-related 2 |
Protein kinase |
TK |
RTK-17 |
|
NP_004551 |
NP_004551 |
943 |
9q21.3 (U) |
|
424 |
MUSK_h |
H |
AF006464 |
AF006464 |
MUSK, NSK2, NP-1, Mdk4, Torpedo,
MLK1 |
Protein kinase |
TK |
RTK-18 |
|
NP_005583 |
NP_005583 |
869 |
9q31.3-9q32 (gene list) |
|
425 |
LMR1_h |
H |
NM_004920 |
NM_004920 |
LMR1_h,
KIAA0641, apoptosis-associated tyrosine kinase |
Protein kinase |
TK |
RTK-19 |
|
NP_004911 |
NP_004911 |
1207+ |
NA |
|
426 |
LMR2_h |
H |
AB029002 |
AB029002 |
LMR2_h, KIAA1079 |
Protein kinase |
TK |
RTK-19 |
|
BAA83031 |
BAA83031 |
1454+ |
7q21.3-22.1 |
|
427 |
LMR3_h |
H |
SUGEN |
SUGEN |
LMR3_h |
Protein kinase |
TK |
RTK-19 |
|
SUGEN |
SUGEN |
|
NA |
|
428 |
SuRTK106_h |
H |
SUGEN |
SUGEN |
SuRTK106_h |
Protein kinase |
TK |
RTK-20 |
|
SUGEN |
SUGEN |
|
12p12.3 (Shirley) |
|
|
|
|
|
|
|
|
|
|
|
|
|
# |
NAME |
Sp |
na ACC# |
Link |
Name/Notes |
Super-family |
Group |
Family |
Homology (AA:AA unless indicated) |
aa ACC# |
|
aa |
CHR location |
|
1 |
CHK |
H |
NM_001277 |
NM_001277 |
KICH_HUMAN CHOLINE KINAS |
PK-like |
Choline Kin |
YKGA |
|
NP_001268 |
NP_001268 |
456 |
|
|
2 |
CHKL |
H |
NM_005198 |
NM_005198 |
choline kinase-like also CAB46629 |
PK-like |
Choline Kin |
YKGA |
|
NP_005189 |
NP_005189 |
433 |
|
|
3 |
DAG-I |
H |
NM_004717 |
NM_004717 |
diacylglycerol kinase, iota |
PK-like |
DAG kin |
DAG kin |
|
NP_004708 |
NP_004708 |
1065 |
|
|
4 |
DGK-a |
H |
X62535 |
X62535 |
diacylglycerol kinase alpha (DIGLYCERIDE
KINASE) (DGK-ALPHA) (DAG KINASE alpha) |
PK-like |
DAG kin |
DAG kin |
|
P23743 |
P23743
|
735 |
|
|
5 |
DGK-d |
H |
L38707 |
L38707 |
diacylglycerol kinase, delta (DIGLYCERIDE
KINASE) (DGK-DELTA) (DAG KINASE DELTA) |
PK-like |
DAG kin |
DAG kin |
|
P52824 |
P52824 |
942 |
|
|
6 |
DGK-e |
H |
D73409 |
D73409 |
PUTATIVE DIACYLGLYCEROL KINASE ETA
(DIGLYCERIDE KINASE) (DGK-ETA) (DAG KINASE ETA) (DIACYLGLYCEROL KINASE,
DELTA) (KIAA0145) |
PK-like |
DAG kin |
DAG kin |
|
Q16760 |
Q16760 |
1169 |
|
|
7 |
DGK-g |
H |
D26135 |
D26135 |
diacylglycerol kinase gamma (DIGLYCERIDE
KINASE) (DGK-GAMMA) |
PK-like |
DAG kin |
DAG kin |
|
P49619 |
P49619 |
791 |
|
|
8 |
DGK-z |
H |
U51477 |
U51477 |
diacylglycerol kinase zeta (DIGLYCERIDE
KINASE) (DGK-ZETA) |
PK-like |
DAG kin |
DAG kin |
|
Q13574 |
Q13574 |
928 |
|
|
9 |
KIAA0718 |
H |
AB018261 |
AB018261 |
KIAA0718 protein |
PK-like |
DAG kin |
DAG kin |
|
BAA34438 |
BAA34438 |
742 |
|
|
10 |
SPHK1A |
|
AF068748 |
AF068748 |
SPHINGOSINE KINASE |
PK-like |
DAG kin |
DAG kin |
|
AAC61697 |
AAC61697 |
504 |
|
|
11 |
ANPa_h |
H |
X15357 |
X15357 |
ANPa, GC-A, Atrial natruiuretic receptor
A |
PK-like |
GCyc |
GCyc |
|
P16066 |
P16066 |
1061 |
NA |
|
|
12 |
ANPb_h |
H |
L13436 |
L13436 |
ANPb_h, NPR-Bi, GC-B, CYGR_h |
PK-like |
GCyc |
GCyc |
256aa ANPa_m 71%; ANPb_h 92% |
P20594 |
P20594 |
1047 |
NA |
|
|
13 |
CYGD_h |
H |
M92432 |
M92432 |
retGC-1, Retinal Guanylyl cyclase 1,
ROS-GC, GC-E_m |
PK-like |
GCyc |
GCyc |
182aa GCyc1_h
retina-specific 92% |
Q02846 |
Q02846 |
1103 |
17p12-p13.2 |
|
14 |
CYGE_m |
M |
L41933 |
L41933 |
GC-E, Guanylate cyclase 2E |
PK-like |
GCyc |
GCyc |
1108aa CYGD_h 85%; CYGF_h 51% |
P52785 |
P52785 |
1108 |
M |
|
|
|
15 |
CYGF_h |
H |
L37378 |
L37378 |
RetGC-2, ROS-GC2, GC-F, Guanylate
cyclase F |
PK-like |
GCyc |
GCyc |
|
P51841 |
P51841 |
1108 |
Xq23 (E) |
|
|
16 |
CYGX_r |
R |
L37203 |
L37203 |
GC-D, olfactory guanylyl cyclase |
PK-like |
GCyc |
GCyc |
1041aa CYGF_h 51%; CYGE_h 52%; CYGD_h 52% |
P51839 |
P51839 |
1110 |
R |
|
|
|
17 |
HSER_h |
H |
338501 |
338501 |
HSER, Heat-stable enterotoxin receptor,
GC-C, STA receptor, intestinal GC |
PK-like |
GCyc |
GCyc |
984aa ANPa_h 33% |
P25092 |
P25092 |
1073 |
12p12.3 (G) |
|
|
|
18 |
KSGC_r |
R |
U33847 |
U33847 |
KSGC, GC-G, Kinase-like doluble Guanylyl
cyclase 48kD |
PK-like |
GCyc |
GCyc |
415aa ANPa_h 50%; ANPb_h 50%; CYGF_h 50% |
P55205 |
P55205 |
433 |
R |
|
|
|
19 |
ATM_h |
H |
U82828 |
U82828 |
ATM, ataxia telangiectasia, PI3Kdomain |
PK-like |
Inositol kinase |
PI3K |
881aa TEL1_sc 29%; ATR_h (Y09077) 29% |
A43100 |
A43100 |
1708 |
11q22.3 |
|
20 |
ATR_r |
H |
Y09077 |
Y09077 |
ATR, FRP1, FRAP-related protein |
PK-like |
Inositol kinase |
PI3K |
548aa ATM_h 29%; FRAP_h 31%; DNAPK_h 26% |
CAA70298 |
CAA70298 |
2644 |
3q22-23 |
|
|
21 |
C2-PI3K_h |
H |
Y11312 |
Y11312 |
Y11312 |
PK-like |
Inositol kinase |
PI3K |
|
CAA72168 |
CAA72168 |
1634 |
1q31 (U) |
|
22 |
DNA-PK_h |
H |
U34994 |
U34994 |
DNA-PK, DNA-activated protein kinase |
PK-like |
Inositol kinase |
PI3K |
|
A57099 |
A57099 |
4096 |
8q11 |
|
|
|
23 |
DNA-PK_m |
M |
AB007544 |
AB007544 |
DNA-PK |
PK-like |
Inositol kinase |
PI3K |
4135aa DNA-PK_h 78% |
BAA28873 |
BAA28873 |
4128 |
M |
|
|
24 |
FRAP_h |
H |
L34075 |
L34075 |
FRAP, FKBP-rapamycin-associated protein,
FRAP2 |
PK-like |
Inositol kinase |
PI3K |
|
P42345 |
P42345 |
2549 |
1p35 (U) |
|
|
25 |
P11A_h |
H |
U79143 |
U79143 |
PI3-K p110 alpha isoform |
PK-like |
Inositol kinase |
PI3K |
|
P42336 |
P42336 |
1068 |
3q25.1-q27 (U) |
|
|
26 |
P11B_h |
H |
S67334 |
S67334 |
PI3-K p110 beta isoform |
PK-like |
Inositol kinase |
PI3K |
|
P42338 |
P42338 |
1070 |
NA |
|
|
27 |
P11D_h |
H |
U86453 |
U86453 |
PI3-K p110 delta isoform |
PK-like |
Inositol kinase |
PI3K |
|
Q00329 |
Q00329 |
1044 |
1p36.1 (U) |
|
28 |
P11G_h |
H |
X83368 |
X83368 |
PI3-K p110 gamma isoform |
PK-like |
Inositol kinase |
PI3K |
|
P48736 |
P48736 |
1101 |
7q22.1 (U) |
|
29 |
p150PI3K_h |
H |
Y08991 |
Y08991 |
p150PI3K_h |
PK-like |
Inositol kinase |
PI3K |
289aa p150PI3K_h (Y08991) 100% VPS15_sc 42% |
CAA70176 |
CAA70176 |
1358 |
NA |
|
|
30 |
PI3KC2b_h |
H |
Y11312 |
Y11312 |
HsC2-PI3K, PI3-K C2 beta isoform, CA74194 |
PK-like |
Inositol kinase |
PI3K |
|
CAA72168 |
CAA72168 |
1634 |
|
31 |
PI3KC2g_h |
H |
NM_004570 |
NM_004570 |
PI3K-C2gamma, third human
C2-domain-containing class II phosphoinositide 3-kinase |
PK-like |
Inositol kinase |
PI3K |
1506aa PI3KC2g_m 69% |
NP_004561 |
NP_004561 |
1448 |
NA |
|
32 |
PI3KC2g_m |
M |
AB008791 |
AB008791 |
PI3K w C2 domain,
third human C2-domain-containing class II
phosphoinositide 3-kinase |
PK-like |
Inositol kinase |
PI3K |
1053/1506 PI3KC2g_h (69%) |
BAA25427 |
BAA25427 |
1560 |
M |
|
33 |
PI4K_h |
H |
AF012872 |
AF012872 |
pi4K230 |
PK-like |
Inositol kinase |
PI3K |
|
P42356 |
P42356 |
854 |
22q11.2-p11.2 (U) |
|
34 |
PI4Kb_h |
H |
NM_002651 |
NM_002651 |
PIK4CB
phosphatidylinositol 4-kinase, catalytic,
beta polypeptide |
PK-like |
Inositol kinase |
PI3K |
|
NP_002642 |
NP_002642 |
829 |
1q12-21.1 (U) |
|
|
|
35 |
PIK3C2A_h |
H |
NM_002645 |
NM_002645 |
PI3K w C2 domain, phosphatidylinositol
3-kinase, class 2, alpha |
PK-like |
Inositol kinase |
PI3K |
1332aa C2-PI3K_h 51%; PI3KC2g_m 34%; PI3KI_h 34% |
NP_002636 |
NP_002636 |
1686 |
NA |
|
36 |
PITR1_h |
H |
Z46973 |
Z46973 |
phosphatidylinositol 3-kinase related to the yeast Vps34p-Vps15p protein sorting system |
PK-like |
Inositol kinase |
PI3K |
|
CAA87094 |
CAA87094 |
887 |
18q12.2 |
|
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