Convergent evolution between metazoan and choanoflagellate phosphotyrosine signaling

The tyrosine kinase signaling networks of choanoflagellates and metazoans are very distinct, with only a few genes clearly orthologous between the two systems. Yet, both systems seem to have come up with similar or identical mechanisms and architectures. This apparent convergent evolution hints at global constraints within the phosphotyrosine signaling networks. Here are some examples. Back to the Monosiga kinome page.