CLUSTAL W (1.83) multiple sequence alignment

NEK4_Hsap       MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
NEK4_Mmus       MPQAAYCYMRVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
Nek4_Ddis       M--DKYDIIKQIGNGSHGDVYLVRSTIDKKKYVMKKIFLKERE--KTKDTLHEVNVLSQL
NEK4_Spur       MSLDLYEHLKVVGKGSYGEVWLVRNKKDKKQFVIKKMELLRASKREKKAAEQEAKLLSKL
                *    *  :: :*.**:*:* **:   * *::*:**: * . .  : : : :*.::**:*

NEK4_Hsap       KHPNIVTYKESWEGG-DGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMAL
NEK4_Mmus       KHPNIVTYKESWEGG-DGLLYIVMGFCEGGDLYRKLKEQKGQLLPESQVVEWFVQIAMAL
Nek4_Ddis       KHPNIVEYFESFQIENNQFLCIIMAYCESGDLFTTLQKKKNEFISEYQILDWFIQIALGL
NEK4_Spur       RHPNIVSYKDSFESE-EGFLYIVMGFCDGGDLYNRLKQQKNAALEERQVVEWFVQIAMAL
                :***** * :*::   : :* *:*.:*:.***:  *:::*.  : * *:::**:***:.*

NEK4_Hsap       QYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFS
NEK4_Mmus       QYLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHGDMASTLIGTPYYMSPELFS
Nek4_Ddis       LYMHKKKVIHRDLKTQNIFLTKKNIIKIGDFGISRVL-NSSEFAKTMIGTPYYMSPECFG
NEK4_Spur       QYMHERNILHRDLYI------------VGD------------------------------
                 *:*:::::****              :**                              

NEK4_Hsap       NKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIR
NEK4_Mmus       NKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPKVYSTELAELIR
Nek4_Ddis       SRAYDFKSDIWSLGCCLYEMITLKHAFDAKEMPSLIFQILQGQPLPISPNYSQDLQNLVY
NEK4_Spur       ----TNQSDVWALGCCVYEMTTLKHAFNAKDMNSLVYKILRGKMPAMPQQYSIELVELIK
                      :**:*:****:*** ******:**:* **:::*:.*:  .:.  ** :* :*: 

NEK4_Hsap       TMLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEA
NEK4_Mmus       TMLSRRPEERPSVRSILRQPYIKHHISLFLEATKAKTSKNNVKNCDSRAKPVAAVVSRKE
Nek4_Ddis       QLLEKQPTKRPSIFDIFQMPYIKRYVEYTLSQNFAVPNNTFVQSFSRMAMETAPI-----
NEK4_Spur       ATLNQSPEKRPSVSRVLRNPYIKKHIAIFLEGTRARRPSTSSESSRRGSKA---------
                  *.: * :***:  ::: ****: :   *. .     ..  :.    :           

NEK4_Hsap       ESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTE-
NEK4_Mmus       ESNTDVIHYQPRSSEGSALHVMGEDKCLSQEKPVDIGPLRSPASLEGHTGKQDMNNTGES
Nek4_Ddis       ------------CNEYANLHLNFN------------------ENGDGTTGAASSNNIYSS
NEK4_Spur       ----------------------------------------------------DLQEIEE-
                                                                    . .:  . 

NEK4_Hsap       LATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVE-EEMLQDNTKS
NEK4_Mmus       CATISRINIDILPAERRDSANAGVVQESQPQHVDAADEVDSQCSISQ-E-KERLQGNTKS
Nek4_Ddis       NYNSNYNN-NNSNNNSNNSNNNNN------------------------------NNNNNN
NEK4_Spur       QSTID--------------------NESGGKDL---------PAISEVPSKKPVRDN---
                  . .                                                 ..*   

NEK4_Hsap       SAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLR
NEK4_Mmus       SDQPGNLLPRRSSDGGDGEGSELVKPLYPSNKDQKPD-----------------------
Nek4_Ddis       NNNNNNFNNN------------FNNNFN-NNNNNNNNN----------------------
NEK4_Spur       --QSKSSIPRPSSAGKERKSAQGVRKSVPSASKEGKS-----------------------
                  :  .                  .      ..:  .                       

NEK4_Hsap       LLGSSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRR
NEK4_Mmus       ------------------------QDQVTG--IIENQDSIHPRSQPHSSMSEPSLSRQRR
Nek4_Ddis       -------------------------------NNNNNNNNNF-------------------
NEK4_Spur       ------------------------RSNV-------------------KTPSEPKLPLK--
                                                                            

NEK4_Hsap       QKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSV
NEK4_Mmus       QKKREQTAHSRTKS-------QFQELPPRLLPSYPGIGKVDIIATQQNDGNQGGPVAGCV
Nek4_Ddis       --NNNNSNNNFNNS-------GFNN------------------NNNNNDGNDGNIINNNN
NEK4_Spur       ------------------------K--SRPLPVPPKGGTPETSKGAKRSTNS----AGSS
                                        :                     :.  *.     .  

NEK4_Hsap       SSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQP-LP
NEK4_Mmus       NSSRTSSTASAKDRPLSARERRRLKQSQEEMLPSGPAVQRTPSAVE-PLKPQEEDQP-IP
Nek4_Ddis       NNNNNNNNNNNNNNNNNNNN-------------------------------NNNNNN---
NEK4_Spur       RTSSSSSVSSSRDDASTP---RTDTGPVDKSPDCEPQVRRSSDAVNRSHDEPDSNHPRRP
                 .. ...  . .:   .                                   :.::    

NEK4_Hsap       ARRLSSDCSVTQ---------ERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINA
NEK4_Mmus       AQRFSSDCSITQMNHTLPREKEKRLMHGLSEDELSSSTSSTDKSDGDSREGKSHTNEMKD
Nek4_Ddis       ------------------------------NNNNNNNNNNNNNGNGNNNINNNNNNNGN-
NEK4_Spur       VAHT--------------------------------------KSDPGSKPQ-RRSPGMKD
                                                          :.: .      ..   : 

NEK4_Hsap       LVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSA
NEK4_Mmus       LVQLMTQTLRLEAKESCEDLQVLNPGSEFRLHRKYRDTLVLHGKVAEEVE-PHCTELPTG
Nek4_Ddis       ------------------------------------------------------------
NEK4_Spur       PIDMPAQRAEIQTQR-YRMMRMKTPSAQ-------------------------AKRRGNA
                                                                            

NEK4_Hsap       IMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSV
NEK4_Mmus       IIPGSEKIRRIVEVLRADVIQGLGIQLLEQVFDLLGEEDELEREARLQEHMGDKYTTYCV
Nek4_Ddis       ------------------NNIGGGLHLLRLGHGHNN------------------------
NEK4_Spur       TMTTSGRLMDRIAMLRKDIMQGIGIELLTKAYELLEKDDDEDTEVGQRSRLLVTRMDDMY
                                     * *:.**   .                            

NEK4_Hsap       KARQLKFFEENMNF
NEK4_Mmus       KARQLKFFEENVSF
Nek4_Ddis       ------ADANSNNN
NEK4_Spur       GCI-LLSFCDSFLN
                         :.