Gene IRAK-14_a-2 (S.moellendorffii)

IRAK-14_a-2

Species: S.moellendorffii
Alias: IRAK-14_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-14

Sequence

Name Sequence Type Origin Length Description Download
IRAK-14_a-2.AA Protein None 458 None Fasta, JSON
IRAK-14_a-2.NA RNA None 1377 None Fasta, JSON
IRAK-14_a-2.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of IRAK-14_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-14_a-2.AA IRAK 119-314 38 1.2e-73 250.99 In-house 1-218 (317) Show / Hide 
Range on Protein: 119-314
Range on HMM: 1-218/317
Sequence Identity: 38% (84 aa)

FDDDLLLGVGGFGKVYKGEINGGT-KVAVK--RGNPMSEQG--MTEFQT---EIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLYGSD-A
|. |...| |||| ||.|.... |  .|||  . . .....  . .||.   |.. ....|| ..|.| ||| |...  |||.||.|| |.  | . | .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

PT---LSWKQRLEICIGAARGLHYLHTGA-QRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVG---PSLDHTHV----STAVKGSFGYLDPEYFR--RQQ
 .   ||| ||..||.|.|.|...||.     .|||.|.|. |||||. |..| .||||   |   ... .. .       |.|.  |. ||. |    |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTEKSDVYSFGVVLMEVV
|| |.||||||.||.||.
LTKKTDVYSFGIVLLEVL
Kinase IRAK-14_a-2.AA TKL 125-389 23 2.1e-62 213.61 In-house 1-364 (364) Show / Hide 
Range on Protein: 125-389
Range on HMM: 1-364/364
Sequence Identity: 23% (87 aa)

LGVGGFGKVYKGEING---------GTKVAVKRGNP---------------------------MSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDENSE-
.| ||||.||||. .|         |. ||||. .                            .... . ..  || |.|.||| ..|...||| ...  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------MILVYDYMANGPLRGHLYGSDAPTLSWKQRLEICIGAARGLHYLHT-----GAQRAIIHRDVKTTNILLDEKFV--------------
            . .|..|. .| |. .|         | ||. .....|||..|||.     .  ..||||| |. |||.||..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKVSDFGLSK-VGPSLDHTHVSTA----------------VKGSFGYLDPEYFRRQ----------------QLTEKSDVYSFGVVLMEVVCARPAINPA
.|..|||||. . .| . .. .|.                . |..... || .| |                . .||.||||||.|| |... ..   | 
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---PY

--LPRDQVSIA---EWALHWQKLGRLSNIMDPRLAG----DCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
  .| ... ..   |. . .  . .|   ..|.        . |  .. . .....| .   ..|||  ..|  |
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-14_a-2.AA TKL-Unique 121-314 33 4.9e-46 159.26 In-house 1-222 (290) Show / Hide 
Range on Protein: 121-314
Range on HMM: 1-222/290
Sequence Identity: 33% (75 aa)

DDLLLGVGGFGKVYKGEINGGTKVAVKRGNP---MSEQGMTEFQTEIEMLSKLR-HRHLVSLIGYCD----ENSEMILVYDYMANGPLRGHLYG------
.  ..| ||.|.||||. . |..||.|. .|    | . | ||  |.  ..||. |  .| ..|||      ...|..| .|.  | |. .|        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--SDAPTLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEK-----FVAKVSDFGLSKVGPSLDHTHVS-------TAVKGSFGYLDPEYF
  ..  .|...||. . | .|.|..|||.     ||||| |..|.|.|..     . .|..||||||.  . . . ..       . ..||| .. || .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

RR--QQLTEKSDVYSFGVVLMEVV
|.   | .|||||||||.|| | .
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase IRAK-14_a-2.AA Dicty4 119-312 33 6.5e-40 130.9 In-house 1-209 (277) Show / Hide 
Range on Protein: 119-312
Range on HMM: 1-209/277
Sequence Identity: 33% (71 aa)

FDDDLLLGVGGFGKVYKGEINGGTKVAVKRG---NP-MSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCD----ENSEMILVYDYMANGPLRGHLYGS---
 . . ..| |.||.||||    |..||||     |   .|  ..||  |.. ..|.|| ... . |.|     . ..|  |  ||  | |   |  .   
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLY-SLLHDKPS

---DAPTLSWKQRLE---ICIGAARGLHYLHTGAQRA--IIHRDVKTTNILLDEKFVAKVSDFGLSK-VGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLT
   .  .|.|  ..    ... ||||. .||.   .   ||||| |. |.| |. ...||.|||||.   .  ||.   ....|. ..  ||  . |  .
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC---CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYN

EKSDVYSFGVVLME
||.|||||| || |
EKADVYSFGIVLWE
Kinase IRAK-14_a-2.AA Pkinase 119-318 28 6.9e-39 138.58 Pfam 1-210 (293) Show / Hide 
Range on Protein: 119-318
Range on HMM: 1-210/293
Sequence Identity: 28% (62 aa)

FDDDLLLGVGGFGKVYKG-EINGGTKVAVKRGNPMSEQGMTEFQT-----EIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANG----PLRGHLYGSD
.     .| |.||.|||. ... | .||||. .   .. . . ||     ||... .|.| . | |.... ..... .| .|. .|     |  .. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

APTL--SWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVA----KVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFR-RQQLTEKS
  ..  |...   ..   .||| |.|   .. |||||.|  |||.|.. .     |..||||.|.   . . .  | . |. .|. ||  | .|  . |.
HGCFYFSEWECKFYMYQILRGLEYCH---SMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVVLMEVVCARP
|..|.|..| |..| ||
DMWSCGCILYEMLCGRP
Kinase IRAK-14_a-2.AA TK 119-314 16 8e-39 127.25 In-house 1-388 (486) Show / Hide 
Range on Protein: 119-314
Range on HMM: 1-388/486
Sequence Identity: 16% (66 aa)

FDDDLLLGVGGFG---KVYKGEINGG--------------------------TKVAVKRGN---PMSEQGMTE--------------FQTEIEMLS--KL
      || | ||   .||||| .|.                          |.||||      .||.. . .              .  |..|..  ..
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHRHLVSLIGYCDEN------------SEMILVYDYMANGP----LRGHLYGSDAP--------------------------------------------
.| ..|.|.|.| ..              ...|  ||..|     || .|  .. .                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------TLSWKQRLEICIGAARGLHYLHTGAQR-----AIIHRDVKTTNILLDEKFV-----------AKVSDFGL
                              .|. .|.| .|  .|.|. |||  ...      ..|||. . |.|..|. |           .|..||||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLH--SKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL

SK-----VGPSLDHTHVSTAVKGSFG---------------------------YLDPEYFRRQQ---------LTEKSDVYSFGVVLMEVV
|.         ... .  .....  .                           .. || .. ..          |.||||.||||.. |..
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIF
Kinase IRAK-14_a-2.AA Pkinase_Tyr 125-314 32 1.5e-38 131.19 Pfam 7-208 (270) Show / Hide 
Range on Protein: 125-314
Range on HMM: 7-208/270
Sequence Identity: 32% (66 aa)

LGVGGFGKVYKGEIN-----GGTKVAVKRG--NPMSEQ-GMTEFQTEIEMLSKL-RHRHLVSLIGYCD-ENSE--MILVYDYMANGPLRGHLYGS--DAP
|| | ||.||||. .     ....||||    . |.||  . .|  |......| .| ..|.|.| |  .     ...|  ||..| |. .|     | .
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

TLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHT-HVSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVV
 |. |. |..|.  |.|. ||.   .. .||||. . |.|..|..|.|..||||..   . |   ....  |     . || ..    |.||||.||||.
PLTMKDLLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVL

LMEVV
. |..
MWEIF
Kinase IRAK-14_a-2.AA MLK 119-314 27 3.6e-38 130.05 In-house 1-230 (291) Show / Hide 
Range on Protein: 119-314
Range on HMM: 1-230/291
Sequence Identity: 27% (64 aa)

FDDDLLLGVGGFGKVYKGEINGGT----KVAVKRGNPMSEQGMTE-------FQTEIEMLSKLRHRH----LVSLIGYCDEN-SEMILVYDYMANGPLRG
..    .|.|.||||.||.  . .     ||||| . . .  . .       |..|.. |..|.|.      . . | | .. ..  .|  |...|.|  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLYG-SDAPT-----------LSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDE------KFVAKVSDFGLSKVGPSLDHTHVS--TAVKG
 |.| .. .             .  . . ..   |||.||||  |. .||||| |  |||.||      . ..|..|||.|.   .. ... .  .  .|
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSR---DWHQMC-TNMMSNAG

SFGYLDPEYF---RRQQLTEKSDVYSFGVVLMEVV
.. .  || .   | .. .||.||.|.|||| |..
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
Kinase IRAK-14_a-2.AA TyrKc 119-389 24 1.5e-35 125.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 119-389
Range on HMM: 1-280/280
Sequence Identity: 24% (73 aa)

FDDDLLLGVGGFGKVYKGEINGGTKVAVKRGNPMSEQGMTEFQTEIEMLSKL--RHRHLVSLIGYCDEN-------SEMILVYDYMANGPLRGHLYGSDA
   .  || | ||.||||. .  ..||||  .. .   . .|  |.....||  .| ..| |.|.| .          . .|  ||..| |. .|  .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

PTLSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSL-------DHTHVST--AVK--GSFGYLDPEYFRRQQLT
  |..|. |..|. .|.|  |||      .||||  . |.|..|....|.||||||. . .        |  ....    |       . || ..    |
K-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKSDVYSFGVVLMEVV--CARPAINPAL-PRDQVSIAEWALHWQKLGRLSNIMDPRLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
.||||.||||.. |.   .. |  .... . .   . |.  .   . .  |.  | ..    ..  ..  .| ..| .   ..||.  ..   .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-14_a-2.AA DRK 126-314 34 1.3e-34 114.68 In-house 8-196 (258) Show / Hide 
Range on Protein: 126-314
Range on HMM: 8-196/258
Sequence Identity: 34% (67 aa)

GVGGFGKVYKGEINGGTKVAVKRGNPMSEQ---GMTEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLYGSDAPTLSWKQRLEICI
| |..| |. |    ||.||||.     .     . ||. ||.....|||   .  .| | . ..   .  ||  | |   |   ..  ..|  .. . .
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH-DESIEMDWPLMKQMMF

GAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSK-VGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLTEKSDVYSFGVVLMEVV
 .|.|. ||| .    ||||| |. | | || .  ||.|||||      ..|.   |.. |  .   ||  | |  ||| |||||..|| |.|
DCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAK-14_a-2.AA TK-Unique 124-315 24 1.8e-31 105.83 In-house 6-234 (294) Show / Hide 
Range on Protein: 124-315
Range on HMM: 6-234/294
Sequence Identity: 24% (57 aa)

LLGVGGFGKVYKGEINGGT-------KVAVKRGN-PMSEQGMTEFQTEIEMLSKLR-HRHLVSLIGYCDENS-EMILVYDYMANGPLRGHLYGSDAP---
..| | || |..||. |..       .||||  . . ...   .|  ||.|...|  | ..|...|.| ...  . ... |...| |...|  .  .   
VIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQ

---------------------TLSWKQRLEICIGAARGLHYLHTGAQ--RAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHTHVSTA--VKGSFG
                     ..| |. . .... |.|. ||   |.  . |.|||. . |.|| |..|.|..|||... .   .. ....    . .  
HQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYL---ASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT-NGVYSMMCSQGRIPIR

YLDPEYFR--RQQL-TEKSDVYSFGVVLMEVVC
.. ||...  ...  |.||||.||||.. |...
WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAK-14_a-2.AA RIPK 125-313 30 1.9e-31 104.4 In-house 1-221 (290) Show / Hide 
Range on Protein: 125-313
Range on HMM: 1-221/290
Sequence Identity: 30% (68 aa)

LGVGGFGKVYKGE-INGGTKVAVKRGN------PMSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDEN-----SE-MILVYDYMANGPLRGHLYGSDA--
.| ||||.|.|      |. ||.|  .      .| .|  ..   | ... |||..| |.. | | .      .. . .|  ||.|| | . |       
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-PTLSWKQRLEICIGAARGLHYLHTGAQRA--IIHRDVKTTNILLDEKFVAKVSDFGLSKV-GPSLDHT--------HVSTAVK--GSFGYLDPEYFR--
 . . |. |  .    ..| .|||        ||||| |. |||.|  | .|..||||..  . |  |.          ..  .  |   |..|| ||  
HHPDPWPLRCRMIHEISCGMCYLH---SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTD

-RQQ---LTEKSDVYSFGVVLMEV
 .      |.|.|||||..|. ||
NKKPIKVVTPKYDVYSFAIVMWEV
Kinase IRAK-14_a-2.AA LRRK 119-310 25 2.7e-29 100.78 In-house 1-272 (351) Show / Hide 
Range on Protein: 119-310
Range on HMM: 1-272/351
Sequence Identity: 25% (72 aa)

FDDDLLLGVGGFG-KVYKGEING---------------------------GTKVAVKRGNP------------------------MSEQGM---------
.    ..|.|||| .||... .|                           ...||.|  |                         . |  |         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

--TEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMANGPLRGHLY--GSDA-----PTLSWKQRLEICIGAARGLHYLHTGAQRA--IIHRDVKT
   ||. |. ..|.|.| ..|||.|.|   . ...| .|. .| |  .|    .|.     . .||  .|.| .  |.|. |||    .   ||||| |.
AFREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKS

TNILL---D---------EKFVAKVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFR---RQQLTEKSDVYSFGVVL
 ||||   .         .  .||..|||.| .  . .|. |   . | .|.. ||  |   . . |||.|.||||..|
PNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMIL
Kinase IRAK-14_a-2.AA S_TKc 119-392 21 4.1e-29 103.96 SMART 1-231 (231) Show / Hide 
Range on Protein: 119-392
Range on HMM: 1-231/231
Sequence Identity: 21% (62 aa)

FDDDLLLGVGGFGKVYKGEING-GTKVAVKRGNPMSEQGMTEFQTEIEMLSKLRHRHLVSLIGYCDENSEMILVYDYMAN--GPLRGHLYGSDAPT----
..   ..| |.||||||.  .. | .||.|. .         .. ||..|.| .| ..| |...... ... .| .|. .  | |. ..     .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSWKQRLEICIGAARGLHYLHTGAQRAIIHRDVKTTNILLDEKFVAKVSDFGLSKVGPSLDHTHVSTAVKGSFGYLDPEYFRRQQLTE-KSDVYSFGVVL
..  .   ..   ...| |.|   .. |||||.|  ||||||  . |..||||...          | . |.  |. || .   . .  |.|..|.|..|
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

MEVVCARPAINPALPRDQVSIAEWALHWQKLGRLSNIMDPRLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLW------NLEYS
 | .| .|        ..  . .  .                       | .    . ..||    ..||.. ..|       . .. 
YEMLCGYPPFP-----QMQMMFKKIG-----------------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-14_a-2.AA IRAK 351-389 20 0.000767 9.69 In-house 279-317 (317) Show / Hide 
Range on Protein: 351-389
Range on HMM: 279-317/317
Sequence Identity: 20% (8 aa)

RLAGDCTPESLQKFGEIAERCLADRGSERPSIGDVLWNL
.....| |.. ...   | .|.. |  .|...  |.  |
HRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAK-14_a-2.AA TK-Unique 369-389 28 0.303947 0.19 In-house 274-294 (294) Show / Hide 
Range on Protein: 369-389
Range on HMM: 274-294/294
Sequence Identity: 28% (6 aa)

ERCLADRGSERPSIGDVLWNL
..|. .  .||||. ...  |
KSCWQWEPEERPSFRQIKHRL