Gene IRAK-Un_aw (S.moellendorffii)

IRAK-Un_aw

Species: S.moellendorffii
Alias: IRAK-Un_aw
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_aw.AA Protein None 553 None Fasta, JSON
IRAK-Un_aw.NA RNA None 1662 None Fasta, JSON
IRAK-Un_aw.kin_dom Protein Kinase Domain None 189 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_aw.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
CLECT IRAK-Un_aw.AA CLECT 1-128 19 5.4e-18 67.02 SMART 1-141 (141) Show / Hide 
Range on Protein: 1-128
Range on HMM: 1-141/141
Sequence Identity: 19% (33 aa)

C---PDGWLRGPA------DRCFMLVNASSTWEESETSCRNRS--------GHLASITSDAEVAFVKSHCTGVFDPCWVGAVISNTSRGVLWRWSDCH--
|   |.|| . |       ..|. ...    |.... .|..          ||||||.| .| .|| |.        |.|.          |.|||    
CPHCPPGWNWYPRPNKYFGGHCYKFFT----WHDAQQFCQSMGPWTHRVQGGHLASIHSQEENDFVQSL-------YWIGLH-------G-WQWSDGSGW

----VRWN-FSFASSN--------------CSSSGCVNLGEYCLSVSSMHGLVRENCGD-----RHRFVCV
    ..|. ...  ..               .. .|| .               .||..     .|.|.| 
IPPTNPWVDYTNWAPGYPNNQPNNWWRHGNGGNGNCVYMW-----------WNDVNCNSNDPYHKHPFICK
Lectin_C IRAK-Un_aw.AA Lectin_C 19-52 32 2e-06 30.58 Pfam 1-40 (122) Show / Hide 
Range on Protein: 19-52
Range on HMM: 1-40/122
Sequence Identity: 32% (13 aa)

ASSTWEESETSCRNRSGH--LASITSDAEV----AFVKSH
 . ||.|... |... ||  |.|| | .|     .|...|
ERMTWHEAQAYCQKMGGHCHLVSIHSQEEQMFIWDFITQH
Lectin_C IRAK-Un_aw.AA Lectin_C 102-129 22 35.345779 0.52 Pfam 92-122 (122) Show / Hide 
Range on Protein: 102-129
Range on HMM: 92-122/122
Sequence Identity: 22% (7 aa)

GEYCLSVSSM---HGLVRENCGDRHRFVCVL
.|.| .....     .  |.|.  |..||  
NEDCVHMWTDTNWGKWNDEHCDWKHPWVCEF
Kinase IRAK-Un_aw.AA TKL 216-474 18 4.7e-45 155.99 In-house 7-364 (364) Show / Hide 
Range on Protein: 216-474
Range on HMM: 7-364/364
Sequence Identity: 18% (68 aa)

GSTFKGILSD---------GVLVAVKKLERSSFQSR---------------------------KEFLAEMNRIARLRHPSLVAVIGCCYDHGE-------
|  .||..           |  |||||. . . ...                           ...  |.. . ||||| .|  .|.| . .        
GEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHP

------RYIAYEYIANGPLDLWLHDPVRRGTLDWRTRMQIAVTAAQGIAYLHDQV-----KPHVIHRDIKASSILLDDKFH--------------GRVMG
       .| .||. .| |   ||         |  |...|  .|.|..||| .      || .||||.| . ||.|....                .  
VGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

VGLASVVPWEAAYE------------------RTVVAGTHGYLAPEFVYRN----------------ELTTKSDVYSFGVLMLELISGRKPAMPVDVVDW
 ||. .. ..   .                  .  . || ...|||    .                | ..|.||||||... |......         .
FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--------PY

QTIFEWATP------LVQSQQLQEIIDPSLTSIPA--------PAHIQMLVDLIYSCTQHVASMRPRMSYVVHQL
. . .          . ...  ..   | . .|.         |   . . .|.  | .| .. || .. ....|
YDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_aw.AA TK 216-474 14 9.2e-31 99.76 In-house 13-486 (486) Show / Hide 
Range on Protein: 216-474
Range on HMM: 13-486/486
Sequence Identity: 14% (71 aa)

G---STFKGILSDG--------------------------VLVAVKKLE---RSSFQSRKE-----------FLAEMNRIARLR-----HPSLVAVIGCC
|     .||.. ..                          . |||| |     .| . ...           ||.|.. .. ..     || .|  .|.|
GSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVC

YDH------------GERYIAYEYIANGP----LDLWLHDPVRRGT------------------------------------------------------
 ..            .  .|  || ..|     |. .|..  ....                                                      
TQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPL

-------------------LDWRTRMQIAVTAAQGIAYLHDQ----VKPHVIHRDIKASSILLDDKFH-----------GRVMGVG--------LASVVP
                   |. .... ... .|.| .|||..    . ....|||. |  .|.... .            ..   |        ||  ..
TTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIY

WEAAYERTVVAGTHG-------------------------YLAPEFVYRNE---------LTTKSDVYSFGVLMLELIS-G-RKPA--MPV-----DVVD
 .  | |.   || .                         ..||| .  ..          ||||||.|||||| |. . |   ..  |.      |   
SDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD---

WQTIFEWATPLVQSQQLQEIIDPSLT------------------SIPAPAHI-------------QMLVDLIYSCTQHVASMRPRMSYVVHQL
               ..||...   .                    |. ..              ... ||. .| .. .. ||..| ...||
-------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_aw.AA TKL-Unique 229-401 27 1.5e-25 87.13 In-house 23-224 (290) Show / Hide 
Range on Protein: 229-401
Range on HMM: 23-224/290
Sequence Identity: 27% (55 aa)

VAVKKLER---SSFQSRKEFLAEMNRIARLR-HPSLVAVIGCCY----DHGERYIAYEYIANGPLDLWLHD-------PVRRGTLDWRTRMQIAVTAAQG
||.|...    ||.....||  | | . .|. || .|  .| |     . ....|  ||.  | |.  ||.         .  .|..  |...|  .|||
VAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQG

IAYLHDQVKPHVIHRDIKASSILLDDK-----FHGRVMGVGLASVVP--WEAAYERT------VVAGTHGYLAPEFVYR--NELTTKSDVYSFGVLMLEL
  |||   .| .||||.| |..|.| .     .  .. ..||. .     .  . .       .. |.  ..|||   .  .  ..||||||||. . |.
MYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEI

ISG
...
ATR
Kinase IRAK-Un_aw.AA Pkinase 224-402 25 5.9e-23 82.24 Pfam 22-209 (293) Show / Hide 
Range on Protein: 224-402
Range on HMM: 22-209/293
Sequence Identity: 25% (49 aa)

SDGVLVAVKKLERSSFQS--RKEFLA--EMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANG----PLDLWLHDPVRRGTL--DWRTRMQIAVTAAQG
..| .||||......  |  ... .   |    .||.||  |  .....|... |.  ||  .|     |  ...   |.|..  ....   ..   ..|
GTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRG

IAYLHDQVKPHVIHRDIKASSILLDDKFHG----RVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVY-RNELTTKSDVYSFGVLMLELISGR
..|.|..    .||||.| . ||.|.. |     ..   ||| .. .      |...|| .|.||| .  ... ..|.|..|.|... |...||
LEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase IRAK-Un_aw.AA Frk 216-399 30 3.3e-22 73.47 In-house 13-196 (260) Show / Hide 
Range on Protein: 216-399
Range on HMM: 13-196/260
Sequence Identity: 30% (58 aa)

GSTFKGILSDGVLVAVKKLERSSFQSRKEFLAEMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRGT-LDWRTRMQIAVTAAQGI
|  . |     . ||||.|   .    ..||.|   . .|||| |. .   |      ||  | . .| |  .|    ..|  .  .. ...|   | |.
GEVWEGLWNNTTPVAVKTLKPGTMDP-NDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQCQMQQLVDMAAQVAAGM

AYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAA--YERTVVAGTH-GYLAPEFVYRNELTTKSDVYSFGVLMLELI
||| .|     ||||. |  .|....   ..   ||| |.  .    ||  . |     . ||| .  |. |.||||.|||.|. |.|
AYLESQ---NYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEII
Kinase IRAK-Un_aw.AA TK-Unique 215-400 26 4.7e-20 65.95 In-house 17-234 (294) Show / Hide 
Range on Protein: 215-400
Range on HMM: 17-234/294
Sequence Identity: 26% (58 aa)

RGSTFKGI--LSDGVLVAVKKLE-RSSFQSRKEFLAEMNRIARLR-HPSLVAVIGCCYDHG-ERYIAYEYIANGPLDLWLH--DPVRRGT----------
||  ....   .. . ||||.|. .........|| | .    |  || .|  .||| . .   .|..||...| |.  |.   |..|..          
RGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDF

-----------LDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTV--VAGTHGYLAPEFVY--RNEL
           .. ..  ..|.  |.| .||. | | ...|||. |. .|| ...   . . |.|  |  . .|...       . ..|||  .  ..  
HHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRK-KIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCYHGMY

-TTKSDVYSFGVLMLELIS
 ||||||.|||||| |. .
HTTKSDVWSFGVLMWEIFT
Kinase IRAK-Un_aw.AA STE 216-402 19 2.6e-19 64.92 In-house 13-265 (359) Show / Hide 
Range on Protein: 216-402
Range on HMM: 13-265/359
Sequence Identity: 19% (53 aa)

GSTFKGILSD----------------GVLVAVKKLERSSF-----------------QSRKEFLAEMNRIARLR--HPSLVAVIGCCYDHG-------ER
|...|..  .                |...|.|... ..                  . ....| |..   ...  ||  |  .||... |       | 
GTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDEL

YIAYEYIANGPLDLWLH-DPVRRGTLDWRT-------RMQIAVTAAQ---G-IAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLA------SVVP
.|. ||...| ||  ..    . ..|.            |||. . |   |  .|||..    .||||||.. |||          | |.      ....
WICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL----------VKLCDFGVCGQLTD

--------------WEAAYERTVVAGTHGYLAPEFVYR------NELTTKSDVYSFGVLMLELISGR
                 . .|. ..||  . ||| . .      .. .||.|..|.| ...|.. |.
SMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAK-Un_aw.AA Pkinase_Tyr 219-330 29 9.8e-19 64.08 Pfam 16-137 (270) Show / Hide 
Range on Protein: 219-330
Range on HMM: 16-137/270
Sequence Identity: 29% (37 aa)

FKGILS-----DGVLVAVKKL-ERSSFQS--RKEFLAEMNRIARL-RHPSLVAVIGCCYDHGER---YIAYEYIANGPLDLWLHDP-VRRGTLDWRTRMQ
.||..      ... ||||.| | .. .   |..|..|..    | .|| .|  .|.|.|.||    ||  || ..| |.  |...   .. |.  .  |
YKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQ

IAVTAAQGIAYLHDQVKPHVIHRDI
...  |.| .||...   . ||||.
MCWQIAKGMEYLESK---NCIHRDL
Kinase IRAK-Un_aw.AA IRAK 219-341 30 3.1e-18 61.34 In-house 16-150 (317) Show / Hide 
Range on Protein: 219-341
Range on HMM: 16-150/317
Sequence Identity: 30% (41 aa)

FKGILSDGV-LVAVKKLER----SSFQSRKEFLA---EMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRGT---LDWRTRMQIA
..| ..     .|||||      |  .....|..   |.   .|.||| .|.. | |.. ..    |.|..|| |   |.     ..   | | .|  |.
YRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSIC

VTAAQGIAYLHDQV-KPHVIHRDIKASSILLDDKF
  .| || .||.   .  .||.||| . ||||. |
WGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHF
Kinase IRAK-Un_aw.AA Dicty4-Unclassified 304-404 34 3.2e-18 58.96 In-house 112-207 (263) Show / Hide 
Range on Protein: 304-404
Range on HMM: 112-207/263
Sequence Identity: 34% (35 aa)

MQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVYRNELTTKSDVYSFGVLMLELISGRK
. .|   |||...||      .||||||.| ||.|  |  ..   |.. |.  .  .  | .|||    .||       . ||||||..... ||. |  
IKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDE

P
|
P
Kinase IRAK-Un_aw.AA MLK 229-346 24 8.9e-17 54.83 In-house 30-172 (291) Show / Hide 
Range on Protein: 229-346
Range on HMM: 30-172/291
Sequence Identity: 24% (35 aa)

VAVKKLE---RSSFQS----RKEFLAEMNRIARLRHPS----LVAVIGCCYDHGE-RYIAYEYIANGPLDLWLHD-PV----------RRGTLDWRTRMQ
||||. .   . . ..    ...|  | .. ..|.||      ... |.| ...   .|  ||...|.|   ||. .           . .. |    |.
VAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMN

IAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDD---KFHGRVM
.|.  |.|..||| . .. .||||.| . ||.|.    .|....
WALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTL
Kinase IRAK-Un_aw.AA TyrKc 216-474 21 3.1e-16 39.73 SMART 13-280 (280) Show / Hide 
Range on Protein: 216-474
Range on HMM: 13-280/280
Sequence Identity: 21% (63 aa)

GSTFKGILSDGVLVAVKKLERSSFQSRKEFLAEMNRIARL--RHPSLVAVIGCCYDH-------GERYIAYEYIANGPLDLWLHDPVRRGTLDWRTRMQI
|  .||...  . ||||.|  ..   |..|. |..   .|  .|| .|. .|.| ..       .  .|  || ..| |.  |... ..  | ...  ..
GEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--LCMKDLLSF

AVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWE----AAYERTVVA---GTHG-----YLAPEFVYRNELTTKSDVYSFGVL
.. .|.| .|||..   ..||||. |  .|...... ..   ||.  .  .    .. .  ...   |...      .|||    .. ||||||.||||.
CWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVC

MLELISGRKPAMPVDV-----VDWQTIFEWATPLVQSQQLQEIIDPSLTSIPAP-----AHIQMLVDLIYSCTQHVASMRPRMSYVVHQL
| |. .    ..|        ...| ..|.    |..    .. .  .     |     ..  |   .. .| .. ...||..| .....
MWEIFTY--GQQPYPGMIQQMMSNQEVIEY----VKQGYRMPQPPNDY-----PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
S_TKc IRAK-Un_aw.AA S_TKc 208-477 19 8.4e-16 54.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 208-477
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

FGMENRLR----GSTFKGILSD-GVLVAVKKLERSSFQSRKEFLAEMNRIARLRHPSLVAVIGCCYDHGERYIAYEYIAN--GPLDLWLHDPVRRGT---
. . . .     |. .|..  . | .||.|..        . .. |..   . .|| .|  .....| .. |.  ||. .  | |   ...  |.|.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILLDDKFHGRVMGVGLASVVPWEAAYERTVVAGTHGYLAPEFVYRNELTT-KSDVYSFGVLML
..  .   ..   .....|.|..   ..||||.| . ||||.  |  .   ||| ..        | . ||  |.||| .     .. |.|..|.|... 
FPE-HARFYMYQICCALEYCHSH---GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELISGRKPAMPVDVVDWQTIFEWATPLVQSQQLQEIIDPSLTSIPAPAHIQMLVDLIYSCTQHVASMRPRMSYVVH------QLDQL
|...|. |       . |..|.                            . . |.|  | |   . ||    . .      .   .
EMLCGYPPFP-----QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_aw.AA IRAK 364-405 43 2.2e-13 43.94 In-house 181-224 (317) Show / Hide 
Range on Protein: 364-405
Range on HMM: 181-224/317
Sequence Identity: 43% (19 aa)

VVAGTHGYLAPEFVY--RNELTTKSDVYSFGVLMLELISGRKPA
.| ||  |..||| .    .||.|.||||||.  ||...|....
HVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAV
Kinase IRAK-Un_aw.AA LRRK 254-337 33 1.9e-12 40.33 In-house 113-199 (351) Show / Hide 
Range on Protein: 254-337
Range on HMM: 113-199/351
Sequence Identity: 33% (30 aa)

RLRHPSLVAVIGCCYDHGERYIAYEYIANGPLDLWLHDPVRRG------TLDWRTRMQIAVTAAQGIAYLHDQVKPHVIHRDIKASSILL
.|.||..|  .| | ..  . .. ||. .| |.  ||.. . |       ..| .. .||.  | |..|||.. .| .|||| |   |||
HLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNILL
Kinase IRAK-Un_aw.AA LRRK 365-404 38 1.3e-08 26.53 In-house 239-282 (351) Show / Hide 
Range on Protein: 365-404
Range on HMM: 239-282/351
Sequence Identity: 38% (17 aa)

VAGTHGYLAPEFVYRN---ELTTKSDVYSFGVLMLELISGR-KP
. |. |..||| .  |   | |.|.|.||||... ||....  |
CVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase IRAK-Un_aw.AA MLK 366-404 33 9.3e-07 19.61 In-house 194-235 (291) Show / Hide 
Range on Protein: 366-404
Range on HMM: 194-235/291
Sequence Identity: 33% (14 aa)

AGTHGYLAPEFV---YRNELTTKSDVYSFGVLMLELISGRKP
|||  . |||       .  . |.||.|.||.. |..... |
AGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-Un_aw.AA Pkinase_Tyr 372-404 52 4e-06 21.33 Pfam 181-214 (270) Show / Hide 
Range on Protein: 372-404
Range on HMM: 181-214/270
Sequence Identity: 52% (18 aa)

LAPEFVYRNELTTKSDVYSFGVLMLELIS-GRKP
.|||    .. ||||||.|||||| |... |..|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase IRAK-Un_aw.AA LRRK 448-476 44 1.2e-05 15.99 In-house 323-351 (351) Show / Hide 
Range on Protein: 448-476
Range on HMM: 323-351/351
Sequence Identity: 44% (13 aa)

MLVDLIYSCTQHVASMRPRMSYVVHQLDQ
|. ||| .| ||    || .|..| .| |
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAK-Un_aw.AA Dicty4-Unclassified 229-267 34 1.3e-05 15.1 In-house 25-67 (263) Show / Hide 
Range on Protein: 229-267
Range on HMM: 25-67/263
Sequence Identity: 34% (15 aa)

VAVKKLERSSFQSR----KEFLAEMNRIARLRHPSLVAVIGCC
|||||.   .|. |    ..|..|      . || || . | |
VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC
Kinase IRAK-Un_aw.AA TK-Unique 452-474 34 0.00015 11.75 In-house 272-294 (294) Show / Hide 
Range on Protein: 452-474
Range on HMM: 272-294/294
Sequence Identity: 34% (8 aa)

LIYSCTQHVASMRPRMSYVVHQL
|..||.|.....||  . ..|.|
LMKSCWQWEPEERPSFRQIKHRL
Kinase IRAK-Un_aw.AA Pkinase_Tyr 451-474 33 0.159921 5.78 Pfam 247-270 (270) Show / Hide 
Range on Protein: 451-474
Range on HMM: 247-270/270
Sequence Identity: 33% (8 aa)

DLIYSCTQHVASMRPRMSYVVHQL
||. .| .. ...||..|....||
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase IRAK-Un_aw.AA MLK 449-474 23 0.211658 0.78 In-house 266-291 (291) Show / Hide 
Range on Protein: 449-474
Range on HMM: 266-291/291
Sequence Identity: 23% (6 aa)

LVDLIYSCTQHVASMRPRMSYVVHQL
.  |.  | .  .. || ....| .|
WKKLMKQCWNQDPHKRPSFRQIVQHL