Gene IRAK-Un_da (S.moellendorffii)

IRAK-Un_da

Species: S.moellendorffii
Alias: IRAK-Un_da
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_da.AA Protein None 558 None Fasta, JSON
IRAK-Un_da.NA RNA None 1677 None Fasta, JSON
IRAK-Un_da.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_da.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_da.AA TKL 165-429 21 6.9e-70 238.5 In-house 1-364 (364) Show / Hide 
Range on Protein: 165-429
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

IGEGGYGIVYKGAVSD---------GTMVACKYLTNKD----------------------------QAEKEFLVEVETIGRVRHKNLVKLLGFCAEGDH-
||.||.|.||||             |. || | .  ..                            ...... .|.  . | || |.|...|.| .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYEYVNNGNLDEWLHGKTSRFKTPSWDSRMKIILGTAKGLAYMHEAI-----EPKIVHRDIKASNILLDSHWN------------
              .|.||. .|.| . ||          |. |....|..|.|..|.|  .      |.|.|||.| .|||.|..|.            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AKVSDFGLAKFLGCEKTHVMTR------------------VMGTFGYVAPEYAN----------------TGLLNERSDVYSFGVLLMEVVTGRDPVD
  .|..||||..|.  ..   .|                   . ||... |||  .                 .  .|..||||||..| |..|.. | .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

-YSRPPGEVNLVDWLKLMLATRRMDDIADPRLEE-------KPSPRALKKALITAFQCVHPDVRKRPTMGHVVHLL
 |  .| ...  . ...|.. .  .    |. ..        | | ...     . .| ..| .|||..  ... |
DYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAK-Un_da.AA IRAK 159-429 32 4.9e-62 212.42 In-house 1-317 (317) Show / Hide 
Range on Protein: 159-429
Range on HMM: 1-317/317
Sequence Identity: 32% (103 aa)

FSERNIIGEGGYGIVYKGAVSDGT-MVACK-----YLTNKDQAEKEFLV---EVETIGRVRHKNLVKLLGFCAEGDHRILVYEYVNNGNLDEWLHGKTSR
|.. | |||||.| ||.|  .  |  .| |       .. .. ...|.    |...  | ||.|.| |.|.|.|..   |||.|  || |   |.. .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

FKTP---SWDSRMKIILGTAKGLAYMHEAIEPK--IVHRDIKASNILLDSHWNAKVSDFGLAKFL----GCEKTHV---MT-RVMGTFGYVAPEYAN--T
  .|   ||  | .| .|||.|. . |.. .|.  | |.||| .||||| | ..| .||||. |     . ||. .   || .| ||  | .||. .  .
-CPPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQ

GLLNERSDVYSFGVLLMEVVTGRDPVDYSRPP--GEVNLVDWLKLMLAT--------------------RRM---DDIADPRLEEKPSPRALKKALIT-A
| |  ..||||||. |.||.||. .|.  ||.  . ..|.. ..   .                     |||    .  |.| .  | |... |..   |
GQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMP--PCPPNMEKEMCQCA

FQCVHPDVRKRPTMGHVVHLL
 .|.|  ...|..|  |. .|
CCCGHHRANRRCDMAWVMQQL
Kinase IRAK-Un_da.AA Pkinase 159-429 23 9.2e-42 148.74 Pfam 1-293 (293) Show / Hide 
Range on Protein: 159-429
Range on HMM: 1-293/293
Sequence Identity: 23% (72 aa)

FSERNIIGEGGYGIVYKG-AVSDGTMVACKYLTNKDQAEKE---FLV--EVETIGRVRHKNLVKLLGFCAEGDHRILVYEYVNNG----NLDEWLHGKTS
.    .||.|..| |||.  ...| .||.| .  ... ...    .   |..   |..|.| |.|.... ..||  .| ||...|     | .....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

RFKTP--SWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNA----KVSDFGLAKFL-GCEKTHVMTRVMGTFGYVAPEYANTGLLN---
| ..   |..   .... ...||.|.|.    .|.|||.| .|||.|.. .     |..||||||..    ..  || . || .|.|||      ..   
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEV-----IRGGQ

---ERSDVYSFGVLLMEVVTGRDPVDYSRPPGEVNLVDWLKLMLATRRMDDIADPRLEEKPS-------------PRALKKALITAFQCVHPDVRKRPTM
    ..|..|.|..| |...|| | . ... .. | .| ....  ... .   |   .  .|             ... . ..     | ..|  |||| 
YYGPKVDMWSCGCILYEMLCGRPPFP-GHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTA

GHVVHL--L
 ....   .
EQILQHPWF
Kinase IRAK-Un_da.AA TK 159-359 17 1e-41 137.11 In-house 1-394 (486) Show / Hide 
Range on Protein: 159-359
Range on HMM: 1-394/486
Sequence Identity: 17% (68 aa)

FSERNIIGEGGYG---IVYKG--------------------------AVSDGTMVACKYLTNK-DQAEKEFLV--------------EVETIGRVR----
    . .||| .|    ||||                           .   | || | |. . .....||.               |.| .   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HKNLVKLLGFCAEG------------DHRILVYEYVNNGN----LDEWLHGKTSRFKT-----------------------------------------
 |.|.|.|.| | .|             . ..| ||...|.    |...|. .  .|..                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------PSWDSRMKIILGTAKGLAYMHEA----IEPKIVHRDIKASNILLDSHWN-----------AKVSDFG--
                               ..   .. . .  |.|..|.|.     | ...||||. | |.|.... .           .|..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LAKFLGCEKTHVMTRVMGTFG-------------------------YVAPEYAN---------TGLLNERSDVYSFGVLLMEVVT-GRDP
      ||. .. ..  . ..  || .                         . |||  |         .|   . |||.|||||. |..| |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase IRAK-Un_da.AA TKL-Unique 163-356 33 1.1e-41 144.76 In-house 3-224 (290) Show / Hide 
Range on Protein: 163-356
Range on HMM: 3-224/290
Sequence Identity: 33% (76 aa)

NIIGEGGYGIVYKGAVSDGTMVACKYLT-NKDQA-E--KEFLVEVETIGRVR-HKNLVKLLGFCA----EGDHRILVYEYVNNGNLDEWLH------GKT
| ||||||| |||| .  |. || | .  | |.  |  .||  || .. . . |.|.|.. |.|.       ....| ||.. |.|.. ||         
NKIGEGGYGQVYKG-KWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

SRFKTPSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSH-----WNAKVSDFGLAKFLGCEKTHVMTRV--------MGTFGYVAPEYANT
.. .....  |.|...  |.|. | |  . | | |||.| ||.|.|..     ||.|..||||.||.  . .   ..         .|.| ..|||  . 
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GLLNERSDVYSFGVLLMEVVTG
   . .| |||||||. | | .|.
NFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAK-Un_da.AA S_TKc 159-429 24 2.6e-38 134.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 159-429
Range on HMM: 1-231/231
Sequence Identity: 24% (70 aa)

FSERNIIGEGGYGIVYKGAVSD-GTMVACKYLTNKDQAEKEFLVEVETIGRVRHKNLVKLLGFCAEGDHRILVYEYVNN--GNLDEWLHGKTS---RFKT
.   ..||.|..| |||.   . |  ||.| .       . .. |..   . .|.|.|||.... . ||  .| ||...  |.| . .. . .   ||. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

PSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFLGCEKTHVMTRVMGTFGYVAPEYANTGLLNE-RSDVYSFGVLLM
|  . | ...  ....|.|.|.    .|.|||.| .|||||.  . |..|||||..|        | . ||  |.|||       .  ..|..|.|..| 
PE-HAR-FYMYQICCALEYCHSH---GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EVVTGRDPVDYSRPPGEVNLVDWLKLMLATRRMDDIADPRLEEKPSPRALKKALITAFQCVHPDVRKRPTMGHVVH---------LL
| ..|. | .        ..   .|...                      . |.    .| . | .||||   . .          .
EMLCGYPPFP--------QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAK-Un_da.AA Dicty4 159-359 32 3.7e-38 124.96 In-house 1-216 (277) Show / Hide 
Range on Protein: 159-359
Range on HMM: 1-216/277
Sequence Identity: 32% (71 aa)

FSERNIIGEGGYGIVYKGAVSDGTMVACKYL--TNKD--QAE-KEFLVEVETIGRVRHKNLVKLLGFCA----EGDHRILVYEYVNNGNLDEWLHG----
    ..||.|..| |||| .  |. || | |  .| .  ... .||. ||.  .  || |.....| |     .      | ||.  ||| . ||     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

KTSRFKTP-SWDSR-MKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFLGCEKTHVM--TRVMGTFGYVAPEYANTGLLNERS
. .. | . .   | |.. . .|.|... |. . | |.|||.|..|.| | .|..||.||||..    ...|    . . || ...|||       || .
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN-PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVLLMEVVTGRDP
|||||| .| | .|. .|
DVYSFGIVLWEILTRQEP
Kinase IRAK-Un_da.AA LISK 164-366 28 1.1e-37 119.87 In-house 1-247 (296) Show / Hide 
Range on Protein: 164-366
Range on HMM: 1-247/296
Sequence Identity: 28% (72 aa)

IIGEGGYGIVYKGAVS-DGTMVACKYLT------NKDQAEKEFLVEVETIGRVRHKNLVKLLGFCAE-GDHRILVYEYVNNGNLDEWLHGKTSRFKTPSW
.||.|..| ||||    .|. .| | ..      |.. ..| .| ||... . ||.| |.  | | .  ..  .| ||.| |.| . |. . .. . ..|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

DSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLD----SHWNAKVSDFGLAKFLGCEK--------------------------------THV--M
. |.|| |. |.|..| |.    .|.||| |. |.|..    . |..|| |||.|. . ||.                                .    |
PQRVKIALDIACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TRVMGTFGYVAPEYANTGLLNERSDVYSFGVLLMEVVTGRDPVD--YSRPP
| . ||   .|||  .    .|..||.|||..| | .|....    . |.|
T-ICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTP
Kinase IRAK-Un_da.AA LRRK 159-361 26 6.7e-37 128.08 In-house 1-284 (351) Show / Hide 
Range on Protein: 159-361
Range on HMM: 1-284/351
Sequence Identity: 26% (77 aa)

FSERNIIGEGGYG-IVYKGAVSD---------------------------GTMVACKYLTNK---------------------------------DQAEK
. . . ||.||.| .||.. . .                           ...|| | ..                                   | ...
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

--EFLVEVETIGRVRHKNLVKLLGFCAEGDHRILVYEYVNNGNLDEWLHGKT-SRF---KTP-SWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNI
  ||  ||  . . .| |.|.|.||| .  ....| ||. .|.|.. || |  ..|   |.  ||  . || |  |||..|.| .  |.|.||| |  ||
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH-NPPIIHRDLKSPNI

LL---D---------SHWNAKVSDFGLAK-FLGCEKTHVMTRVMGTFGYVAPEYANTG---LLNERSDVYSFGVLLMEVVTGR-DPVD
||   .          | .||..|||.   |  | .. |  .. |..|..|||  . .     .| .|.||||..| | .|.. .| |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase IRAK-Un_da.AA Dicty4-Unclassified 162-359 34 3e-36 121.63 In-house 4-207 (263) Show / Hide 
Range on Protein: 162-359
Range on HMM: 4-207/263
Sequence Identity: 34% (73 aa)

RNIIGEGGYGIVYKGAVSDGTMVACKYL-TNKDQAE----KEFLVEVETIGRVRHKNLVKLLGFCAEG-DHR---ILVYEYVNNGNLDEWLHGKTSRFKT
   ||.|    |.||    |  || | .  ||...     ..|. |||  | . | ||||. | |     |.   . | |    ||| |  | | |  . 
DQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

P-SWDS--RMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFLGCEKTHVMTRVMGTFGYVAPEYANTGLLNERSDVYSFGVL
| . |.   .|. .  |.|....|      ..|||||.||||.| | |.|. |||..     . .  || . ||    .||       | .|||||....
PIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LMEVVTGRDP
| | .||  |
LYELATGDEP
Kinase IRAK-Un_da.AA MLK 159-359 26 4.5e-36 122.68 In-house 1-235 (291) Show / Hide 
Range on Protein: 159-359
Range on HMM: 1-235/291
Sequence Identity: 26% (63 aa)

FSERNIIGEGGYGIVYKGAVSDGT----MVACKYLT-------NKDQAEKEFLVEVETIGRVRHKN----LVKLLGFCAE-GDHRILVYEYVNNGNLDEW
. .  .||.|..| |.||     .     || |  .        ..   ..|  |..   ...|.|     ....| |.. . |  .| ||. .| | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHGKTSRFK----------TPSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDS------HWNAKVSDFGLAKFLGCEKTHVMTRVMGTFGY
|||..|             . . |. |.. |  |.|..| |.   ..|.|||.| .|||.|       | ..|..|||..... . .   |.  .||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

VAPEY---ANTGLLNERSDVYSFGVLLMEVVTGRDP
 |||    .  .  .| .||.|.||.| |..|.. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAK-Un_da.AA RIPK 165-359 28 1.5e-35 118.58 In-house 1-227 (290) Show / Hide 
Range on Protein: 165-359
Range on HMM: 1-227/290
Sequence Identity: 28% (66 aa)

IGEGGYGIVYKGA-VSDGTMVACKYLT--N-----KDQAEKEFLVEVETIGRVRHKNLVKLLGFCAEGDH------RILVYEYVNNGNLDEWLHGKTS-R
.| || | |.|   .. |..|| |  .  .     .|| ... . |..   . |... |...||| . .         .| ||  ||.| . || |..  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

FKTPSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFLGCEKTHV----------MTRVM--GTFGYVAPEYANTGLL
 .   |. |  .|  .. |  | |  . | | ||| | .|||.|.. ..|..|||||....  . |           |.     ||  | .||  .|.. 
HHPDPWPLRCRMIHEISCGMCYLHS-MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

NE------RSDVYSFGVLLMEVVTGRDP
.        .|||||.... || |.. |
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAK-Un_da.AA TyrKc 159-429 22 1.6e-34 121.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 159-429
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

FSERNIIGEGGYGIVYKGAVSDGTMVACKYLTNKDQAEKEFLVEVETIGRV--RHKNLVKLLGFCAEG-------DHRILVYEYVNNGNLDEWLHGKTSR
 .   ..||| .|.||||  .  ..|| | | .    ...|. | .   ..  .|.|.|.|.| | ..       .   .| ||. .|.|.. |. .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

FKTPSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFLGCE-------KTHVM-----TRVMGTFGYVAPEYANTGLL
    ...   .. .  |.| .| |.    ...|||. | |.|...   .|.|||||..... .       .. ..     .. |      |||  |.|  
---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

NERSDVYSFGVLLMEVVTGRDPVDYSRPPGE-----VNLVDWLKLMLATRRMDDIAD--PRLEEKPSPRALKKALITAFQCVHPDVRKRPTMGHVVHLL
.. |||.||||.. |. |  ..     |. .     ..  . ...  . .||.  ..  | .    .... ..      || | |  .|||.  .....
TTKSDVWSFGVCMWEIFTYGQQ-----PYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYP-MS---FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAK-Un_da.AA Pkinase_Tyr 159-359 27 1.1e-33 114.68 Pfam 1-214 (270) Show / Hide 
Range on Protein: 159-359
Range on HMM: 1-214/270
Sequence Identity: 27% (61 aa)

FSERNIIGEGGYGIVYKGAVS-----DGTMVACKYL--TNKDQA--EKEFLVEVETIGRV-RHKNLVKLLGFCA-EGDH--RILVYEYVNNGNLDEWLHG
 .    .||| .| ||||        ... || | |  .  ...   ..|. |...     .|.|.|.|.| |  .|..   ..| ||. .|.|.. |. 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K-TSRFKTPSWDSRMKIILGTAKGLAYMHEAIEPKIVHRDIKASNILLDSHWNAKVSDFGLAKFL-----G-CEKTHVMTRVMGTFGYVAPEYANTGLLN
. ... . .  |   .. .  |||..| ..    ...|||. | |.|...   .|..|||||. .         ... .  .  .    |||  |.|  .
HREDKQPLTMKD-LLQMCWQIAKGMEYLESK---NCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWM----APECINYGKFT

ERSDVYSFGVLLMEVVT-GRDP
. |||.|||||. |..| |. |
TKSDVWSFGVLMWEIFTYGEQP
Kinase IRAK-Un_da.AA TK 410-429 40 0.001292 7.14 In-house 467-486 (486) Show / Hide 
Range on Protein: 410-429
Range on HMM: 467-486/486
Sequence Identity: 40% (8 aa)

QCVHPDVRKRPTMGHVVHLL
|| |.| ..|||.  ... |
QCWHYDPEDRPTFSQLHEQL
Kinase IRAK-Un_da.AA Dicty4-Unclassified 411-429 47 0.006553 5.76 In-house 245-263 (263) Show / Hide 
Range on Protein: 411-429
Range on HMM: 245-263/263
Sequence Identity: 47% (9 aa)

CVHPDVRKRPTMGHVVHLL
| | | .|||||  ..  |
CWHNDPNKRPTMNQIIQYL
Kinase IRAK-Un_da.AA MLK 410-429 40 0.014722 4.85 In-house 272-291 (291) Show / Hide 
Range on Protein: 410-429
Range on HMM: 272-291/291
Sequence Identity: 40% (8 aa)

QCVHPDVRKRPTMGHVVHLL
|| ..| .|||.. ..|  |
QCWNQDPHKRPSFRQIVQHL
Kinase IRAK-Un_da.AA TKL-Unique 410-429 40 0.16391 1.32 In-house 271-290 (290) Show / Hide 
Range on Protein: 410-429
Range on HMM: 271-290/290
Sequence Identity: 40% (8 aa)

QCVHPDVRKRPTMGHVVHLL
|| |.|  .||.   ..| |
QCWHHDPSQRPSFDEIIHRL
Kinase IRAK-Un_da.AA Pkinase_Tyr 410-429 40 0.344791 4.65 Pfam 251-270 (270) Show / Hide 
Range on Protein: 410-429
Range on HMM: 251-270/270
Sequence Identity: 40% (8 aa)

QCVHPDVRKRPTMGHVVHLL
|| |.|  .|||.  ... |
QCWHYDPEDRPTFSEIHEQL