IRAK-Un_dg

Species: S.moellendorffii
Alias: IRAK-Un_dg
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_dg.AA Protein None 368 None Fasta, JSON
IRAK-Un_dg.NA RNA None 1107 None Fasta, JSON
IRAK-Un_dg.kin_dom Protein Kinase Domain None 201 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_dg.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_dg.AA TKL 85-221 23 5.7e-34 119.18 In-house 1-195 (364) Show / Hide
Range on Protein: 85-221
Range on HMM: 1-195/364
Sequence Identity: 23% (48 aa)

IGQGSTNRVYKGILSD---------GMEVAVKKLKQDVS------------------------ECSDVEASFRFQMELLSRVHHQHLANLVGICDEKQE-
||.|.   ||||..           | .|||||.|.. .                        | |  .  ..... ..|| .|...  ..|.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RMLLFQYAPNGTLFENLHTGDENLSWKQRMRIIVGAAYGLAYLHHLCN-----PPVIHGDLRSRNILLTEDFA--------------A
             ..  .|.|.|.|...||       | ||.|.. ..| |..|||         ||.|| || |.|||. |..               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KV
|.
KI

Kinase IRAK-Un_dg.AA IRAK 82-342 26 1.8e-32 112.41 In-house 4-317 (317) Show / Hide
Range on Protein: 82-342
Range on HMM: 4-317/317
Sequence Identity: 26% (84 aa)

SNLIGQGSTNRVYKGILSDGME--VAVKKLKQDV-SECSDVEASFRF---QMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLHTGDE--N
.|.||.|    ||.| . .. .  .||||||. . ...  .. .|.     .....| .| ..  | | | | |.  | ..| |||.|.  |.  |    
DNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCP

---LSWKQRMRIIVGAAYGLAYLHHLC-NPPVIHGDLRSRNILLTEDFAAKV--WAMVVP-------IAGSS---ELALVRKTGGYVDPEIVH--RGVYS
   ||| ||  |  |.| |. .|| .    |.||||  | |||| ..| .|    ... .        ....   .  .||.|  |  ||      | ..
PKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLT

RAGDVFSFGVLLLEVLSGK-QAFSE--ETGMLVEWAQQFLQSRD---------------------RMM----DLVDKSMSNVCPMELYSVCELARLCTQR
   ||.|||. |||||.|  .. ..  |.  |..  .   ...                      | |    ...|. |. . | .  . | .|  |. .
KKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPPCPPNMEKEMCQCACCCGHH

ESSSRPSMRDVSDLL
    |..|. |  .|
RANRRCDMAWVMQQL

Kinase IRAK-Un_dg.AA TKL-Unique 81-221 26 3.9e-24 82.11 In-house 1-158 (290) Show / Hide
Range on Protein: 81-221
Range on HMM: 1-158/290
Sequence Identity: 26% (43 aa)

FSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECS-DVEASFRFQMELLSRVH-HQHLANLVGICD----EKQERMLLFQYAPNGTLFENLH------
|.|.||.|.  .||||.   | .||.|...   .. | ...  |. .  .... | |  .  ..|.|        .. .   | | |.| ..||      
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---TGDENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTED-----FAAKV
       .|...||....  .| |. ||||.  | .||.||.|.|.|....     . .|.
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKI

Pkinase_Tyr IRAK-Un_dg.AA Pkinase_Tyr 74-221 23 4.5e-23 78.77 Pfam 1-152 (270) Show / Hide
Range on Protein: 74-221
Range on HMM: 1-152/270
Sequence Identity: 23% (39 aa)

VELLSEGFSNLIGQGSTNRVYKGILS-----DGMEVAVKKLKQDVSECSDVE---ASFRFQMELLSRV-HHQHLANLVGICD-EKQE--RMLLFQYAPNG
.... .     .|.|.  .||||..      ....||||.||.    ... .   ..|   .....   ||... .|.|.|  ...    .. . |.|.|
ITFGKK-----LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG

TLFENLHTG---DENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV
 | . |..    ...|. |.   . .  | |..||.       || ||. ||.|.||.. .|.
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKI

Kinase IRAK-Un_dg.AA TK 92-221 13 1.4e-21 68.45 In-house 17-292 (486) Show / Hide
Range on Protein: 92-221
Range on HMM: 17-292/486
Sequence Identity: 13% (37 aa)

RVYKGILSDG--------------------------MEVAVKKLKQD-VSECSDVEA-------------SFRFQMELLS--RVHHQHLANLVGICDEK-
.||||.. ..                          ..|||| || .  ..  . ..             ..   |....    ||... .|.|.| .. 
EVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGE

-----------QERMLLFQYAPNGT----LFENLHTGDEN------------------------------------------------------------
           .  |..  |.|.|     | . |.. ...                                                            
PKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKD

---------------LSWKQRMRIIVGAAYGLAYLHHL----CNPPVIHGDLRSRNILLTEDFA-----------AKV
               |. .|.. . . .| |..||| .      . ..|.||  ||.|..|.             .|.
LLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKI

Kinase IRAK-Un_dg.AA MLK 79-221 22 9.4e-18 58.26 In-house 1-174 (291) Show / Hide
Range on Protein: 79-221
Range on HMM: 1-174/291
Sequence Identity: 22% (39 aa)

EGFSNLIGQGSTNRVYKGILSDGME-----VAVKKLKQDVSECSDVE----ASFRFQMELLSRVHHQH----LANLVGICDEK-QERMLLFQYAPNGTLF
  |.  || ||   |.||    ...     ||||. ...   .. ..      |.   ..|... |.        ..|.| .  ..  .. .|...| |.
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLY

ENLHTGDE-------------NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTE------DFAAKV
. ||...              . .  . |.. .  | |..||| .  .|.|| || |.|||..|      .  .|.
NVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKI

Kinase IRAK-Un_dg.AA LRRK 79-213 22 9.9e-18 59.29 In-house 1-199 (351) Show / Hide
Range on Protein: 79-213
Range on HMM: 1-199/351
Sequence Identity: 22% (46 aa)

EGFSNLIGQGSTN-RVYKGILSD---------------------------GMEVAVKKLKQD-------------------------------VSECSDV
  . ..||.|... .||.... .                           . .||.||.. |                                ..|. .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

EASFRFQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLH--TGDE------NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNI
  .||  . ..|. .| .. .|.|.|   . ...   |||.|.| . ||    |.      ..||  . .| .  | |..|||  .|||.|| ||.| ||
FREFRHEVWIMSHLNHPNIVSLKGFC--IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL
||
LL

Kinase IRAK-Un_dg.AA TKL-ciliate1 81-220 26 2e-17 56.2 In-house 3-145 (279) Show / Hide
Range on Protein: 81-220
Range on HMM: 3-145/279
Sequence Identity: 26% (39 aa)

FSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSEC--SDVEASFRFQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNGTLFENLHTGDE---NLS
. . || |.   ||||  .   .||..... . |.    .  . .|    .   . |  |  |.||   .    .   . . ||.|. .|        ..
MGQKIGSGHFCNVYKGRCNS-YDVAIMNMNYFNSQESFINQKEFQREIQQHIKIKQHINLQQLQGISFYDNNFYIIMEHCHKGTMFDICHRKHSQIYMIK

WKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAK
| .|||..   | |. ||| . ..| || || . |||. |..  |
WQHRMRWCKDIAQGMQYLHMR-QNPLIHRDLKMQNILYDEPYQYK

Kinase IRAK-Un_dg.AA TyrKc 79-342 22 6.4e-17 50.83 SMART 1-280 (280) Show / Hide
Range on Protein: 79-342
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

EGFSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECSDVEASFRFQMELLSRV--HHQHLANLVGICDEK-------QERMLLFQYAPNGTLFENLHT
  .   .| |   .||||...  ..||||.|| |       .. |.  .......  ||... .|.|.| ..       .  |... |.|.| | . |. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

GDENLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV--WAMVVPIAGS-----SELALVRKTGGYVD---------PEIVHRGV
  ..|..|.   . . .| | .|||.    ..|| ||  ||.|..|.. .|.    .   |        |.   . |...  .         ||    |.
HRPKLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

YSRAGDVFSFGVLLLEVLS-GKQAFSEETG--MLVEWAQQFLQSRDRMMDLVDKSMSNV-------CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
.. . ||.||||.. |... |.|  ....   |  . . .......||.      . |.       || |.|   .. . | ... ..||..... ...
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMP-----QPPNDYPMSFVCCPDEMY---QIMKQCWHEDPEDRPTFSEIHECF

Kinase IRAK-Un_dg.AA Dicty5 80-221 26 5.6e-16 51.49 In-house 2-145 (260) Show / Hide
Range on Protein: 80-221
Range on HMM: 2-145/260
Sequence Identity: 26% (40 aa)

GFSNLIGQGSTNRVYKGILSDGMEVAVKKLKQDVSECSDVEASFRFQMELLSRVH--HQHLANLVGICDEKQER-MLLFQYAPNGTLFENLHTGDE----
 |   |  |.  |||.||   || ||.| . |..  | | . .|     ..| .   |  ..   |     .     .  |  ||.||. |         
SFHDWIASGASGRVYNGIY-KGMDVAIKVYSQENCMCFDWN-EFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

NLSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV
.... |.. . ...| .. .||      .|| || | |.|.||.. .|.
PIAYFQQLHMAIDIAQSMRHLHSMN---IIHRDLKSMNFLITENWKIKI

Kinase IRAK-Un_dg.AA S_TKc 79-347 18 2.4e-14 33.43 SMART 1-231 (231) Show / Hide
Range on Protein: 79-347
Range on HMM: 1-231/231
Sequence Identity: 18% (52 aa)

EGFSNLIGQGSTNRVYKGILSD-GMEVAVKKLKQDVSECSDVEASFRFQME--LLSRVHHQHLANLVGICDEKQERMLLFQYAPN--GTLFENLHTGDEN
  . ..||.|.  .|||..  . | .||.|..|             ... |  .|.. || .. .| ..... ..  . . |...  |.||. ..    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH

-----LSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAAKV----WAMVVPIAGSSELALVRKTGGYVDPEIVHRGVYSR-AGDVFSF
     ..  .  ...   . .|.|.| .    .|| ||   ||||.|    |.     | ..          .  |  |. ||..    |.. . |. |.
GLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSC

GVLLLEVLSGKQAFSEETGMLVEWAQQFLQSRDRMMDLVDKSMSNVCPMELYSVCELARLCTQRESSSRPSMRDVSD----LLVQSLA
|..| | |.|.  |.     . .  .. .                       ..... | | |.. . ||.  ..             
GCILYEMLCGYPPFP----QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAK-Un_dg.AA UTK 81-216 23 3.3e-14 45.03 In-house 3-154 (296) Show / Hide
Range on Protein: 81-216
Range on HMM: 3-154/296
Sequence Identity: 23% (38 aa)

FSNLIGQGSTNRVYKGILSD------GMEVAVKKLKQDVSECSDVEASFRFQME-------------LLSRVH-HQHLANLVGICDEKQERMLLFQYAPN
.....|||    |.|. . .       | ||||...        ..|. ....|             .....| |.....|||.|   .  |..  |..|
LGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQ--------HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMEN

GTLFENLHTGDEN-------LSWKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTED
| |   | .  ..       |.  ||.   .  | |..|||      ..|.||  ||.|....
GDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCG---FVHRDLAARNCLVHMH

Kinase IRAK-Un_dg.AA TK-Unique 81-221 22 4e-14 45.2 In-house 3-174 (294) Show / Hide
Range on Protein: 81-221
Range on HMM: 3-174/294
Sequence Identity: 22% (40 aa)

FSNLIGQGSTNRVYKGILSDGM-------EVAVKKLKQDVSECSDVEASFRFQMELLSRVH-HQHLANLVGICDEKQ-ERMLLFQYAPNGTLFENLHTGD
. ..||.|.   |..| .. ..        ||||.|| .... .. .   ..||  .. .  |... ...|.| ...   |... |.|.|.|   |.|  
VGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQM--MKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

EN-------------------------LSWKQRMRIIVGAAYGLAYLHH-LCNPPVIHGDLRSRNILLTEDFAAKV
 .                         .| |.  ..... | |..||.  ...  ..|.|| .||.|||||. .|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKK--IVHRDLCARNVLLTEDKVCKI

Kinase IRAK-Un_dg.AA TKL 245-342 20 7.8e-14 46.2 In-house 258-364 (364) Show / Hide
Range on Protein: 245-342
Range on HMM: 258-364/364
Sequence Identity: 20% (23 aa)

DPEIVHRGVYSRAGDVFSFGVLLLEVLSGKQAFSEETGMLVEWA-----QQFLQSRDRMMDLVD-------KSMSNVCPMELYSVCELARLCTQRESSSR
|. . . . || . ||.|||..| |.|.... ....  | ....      . . . ...  ...       | |   ||  . |...|.  | . . ..|
DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHK-M-CPCPDCPPSMKKLMQDCWDHDPEKR

PSMRDVSDLL
||. .. . |
PSFQEILKRL

Kinase IRAK-Un_dg.AA Pkinase 85-221 22 6e-09 32.73 Pfam 7-153 (293) Show / Hide
Range on Protein: 85-221
Range on HMM: 7-153/293
Sequence Identity: 22% (34 aa)

IGQGSTNRVYKGILSDGME-VAVKKLKQDVSECSDVEASFR-FQMELLSRVHHQHLANLVGICDEKQERMLLFQYAPNG----TLFENLH-TGDENL--S
||.||  .|||..  .  . ||||..| .  ...  .. .|    ... |..| .   | ... .|..  . . |...|     ||. ..   . ..  |
IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFS

WKQRMRIIVGAAYGLAYLHHLCNPPVIHGDLRSRNILLTEDFAA----KV
...  ...   . ||.|.|      .|| || . |||. ..       |.
EWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKI

Kinase IRAK-Un_dg.AA TK 246-342 17 7.1e-09 25.09 In-house 354-486 (486) Show / Hide
Range on Protein: 246-342
Range on HMM: 354-486/486
Sequence Identity: 17% (23 aa)

PEIVH---------RGVYSRAGDVFSFGVLLLEVLS-GKQAFSEETGMLVEWA----QQFLQSRDRMMDL-----------VDKSMSNVCP---------
|| .           |... . ||.|||||. |... |.. . ..      |.    |....   |   |             .     ||         
PECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHP

--MELYSVCELARLCTQRESSSRPSMRDVSDLL
  ..   . .| . | ... . ||..... . |
PHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL

Kinase IRAK-Un_dg.AA UTK 246-273 31 7.6e-07 19.46 In-house 208-236 (296) Show / Hide
Range on Protein: 246-273
Range on HMM: 208-236/296
Sequence Identity: 31% (9 aa)

PEIVHRG-VYSRAGDVFSFGVLLLEVLSG
||..  .  .... ||.||||.. |....
PEALTHHTRFTTKSDVWSFGVVCWEIWTW

Kinase IRAK-Un_dg.AA TK-Unique 246-272 40 4e-05 13.77 In-house 205-234 (294) Show / Hide
Range on Protein: 246-272
Range on HMM: 205-234/294
Sequence Identity: 40% (12 aa)

PEIVH--RGVY-SRAGDVFSFGVLLLEVLS
||.    .|.| .  .|| |||||. |...
PESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_dg.AA LRRK 246-279 34 4.5e-05 13.87 In-house 248-285 (351) Show / Hide
Range on Protein: 246-279
Range on HMM: 248-285/351
Sequence Identity: 34% (13 aa)

PEIVHRG---VYSRAGDVFSFGVLLLEVLSGK-QAFSE
|||.  .   .|.   |..|||..| | |... ..| |
PEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDE

Kinase IRAK-Un_dg.AA MLK 254-274 47 0.000191 11.48 In-house 213-233 (291) Show / Hide
Range on Protein: 254-274
Range on HMM: 213-233/291
Sequence Identity: 47% (10 aa)

YSRAGDVFSFGVLLLEVLSGK
||.. ||.|.||.| |.|...
YSEKCDVWSWGVVLWEMLTRE

Kinase IRAK-Un_dg.AA Pkinase 246-280 30 0.001771 13.38 Pfam 180-215 (293) Show / Hide
Range on Protein: 246-280
Range on HMM: 180-215/293
Sequence Identity: 30% (11 aa)

PEIVH-RGVYSRAGDVFSFGVLLLEVLSGKQAFSEE
||..  .  |... |..|.|..| |.|.|.  |...
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH

Kinase IRAK-Un_dg.AA TKL-Unique 246-275 37 0.002195 8.01 In-house 195-226 (290) Show / Hide
Range on Protein: 246-275
Range on HMM: 195-226/290
Sequence Identity: 37% (12 aa)

PEIVHR--GVYSRAGDVFSFGVLLLEVLSGKQ
||.  .    ||.  ||.|||. | | ...|.
PEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI

Kinase IRAK-Un_dg.AA Pkinase_Tyr 246-275 41 0.004757 10.95 Pfam 183-213 (270) Show / Hide
Range on Protein: 246-275
Range on HMM: 183-213/270
Sequence Identity: 41% (13 aa)

PEIVHRGVYSRAGDVFSFGVLLLEVLS-GKQ
||  . |... . || |||||. |... |.|
PECINYGKFTTKSDVWSFGVLMWEIFTYGEQ

Kinase IRAK-Un_dg.AA TK-Unique 324-342 42 0.009695 5.42 In-house 276-294 (294) Show / Hide
Range on Protein: 324-342
Range on HMM: 276-294/294
Sequence Identity: 42% (8 aa)

CTQRESSSRPSMRDVSDLL
|.|.| ..||| |.. . |
CWQWEPEERPSFRQIKHRL

Kinase IRAK-Un_dg.AA Dicty5 240-281 26 0.010581 5.12 In-house 166-207 (260) Show / Hide
Range on Protein: 240-281
Range on HMM: 166-207/260
Sequence Identity: 26% (11 aa)

TGGYVDPEIVHRGVYSRAGDVFSFGVLLLEVLSGKQAFSEET
|  .  .|.     |    ||.|||. | |..  | .. . .
TQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNIN

Kinase IRAK-Un_dg.AA UTK 310-342 24 0.021283 4.02 In-house 267-296 (296) Show / Hide
Range on Protein: 310-342
Range on HMM: 267-296/296
Sequence Identity: 24% (8 aa)

CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
||...|   .| . | . . . ||...|. . .
CPHPVY---RLMHRCWHYDPQERPDFEDLVQQM

Kinase IRAK-Un_dg.AA LRRK 323-344 27 0.032035 3.64 In-house 330-351 (351) Show / Hide
Range on Protein: 323-344
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCTQRESSSRPSMRDVSDLLVQ
.| | .  .||.. .. . | |
HCWQHDPKKRPHFSQIVKRLSQ

Kinase IRAK-Un_dg.AA Pkinase_Tyr 310-342 27 2.329273 1.84 Pfam 241-270 (270) Show / Hide
Range on Protein: 310-342
Range on HMM: 241-270/270
Sequence Identity: 27% (9 aa)

CPMELYSVCELARLCTQRESSSRPSMRDVSDLL
|| |.|   .| ..| . . . ||.....   |
CPDEIY---DLMKQCWHYDPEDRPTFSEIHEQL