IRAK-Un_df

Species: S.moellendorffii
Alias: IRAK-Un_df
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
IRAK-Un_df.AA Protein None 574 None Fasta, JSON
IRAK-Un_df.NA RNA None 1725 None Fasta, JSON
IRAK-Un_df.kin_dom Protein Kinase Domain None 213 None Fasta, JSON

Protein domain

Protein domains of IRAK-Un_df.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAK-Un_df.AA TKL 243-449 22 7.8e-52 178.53 In-house 1-284 (364) Show / Hide
Range on Protein: 243-449
Range on HMM: 1-284/364
Sequence Identity: 22% (69 aa)

IGEGSYGHVYKGTLHR----------TNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHG----------------KIKVEVL---SRLHHPHIVLL
||.|..| ||||...           . ||||... .. .   . .||           .  .                . ..|..   |||.||.||..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQEN---------ND-NNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQF

LG---------------GNPEKKCLVYEYLENGSLEDRLFCKDDSPPISCLTRYQIAVEVGTALLFLHKAKP-----QPIVLRDLKPSNILLDKNYN---
.|               |.. . |.|.|| ..|||...|             | ..| ..  .. .||  .|      ||. ||||..|||.|.|..   
MGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS

-----------SKISDVGLARFMPGDE-----------------TSVRSTSPVGTFAYIDPEY----------------QREGSFNAKSDVFAFGIILLQ
            ||.| ||.||| ...                 .. .. ...||...  ||                 ....... |.||..|||.|  
NYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE

LLT
.||
ILT

Kinase IRAK-Un_df.AA IRAK 299-449 39 2.5e-36 126.32 In-house 54-219 (317) Show / Hide
Range on Protein: 299-449
Range on HMM: 54-219/317
Sequence Identity: 39% (65 aa)

VEVLSRLHHPHIVLLLG--GNPEKKCLVYEYLENGSLEDRLFCKD-DSPP--ISCLTRYQIAVEVGTALLFLHKAKPQ-PIVLRDLKPSNILLDKNYNSK
..|..|..||.|| |.|    ... ||||.|. |||||||| | | . ||   |  .|  |.   . .. ||| . |  ||  .| |..|||||.. . |
LKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPK

ISDVGLARFM----PGDETSV---RSTSPVGTFAYIDPEYQR--EGSFNAKSDVFAFGIILLQLLT
|.| ||.||         ...   .    .|| .|  ||. |   |    |.||. ||| || .||
ICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLT

Kinase IRAK-Un_df.AA MLK 237-449 27 9.8e-35 117.96 In-house 1-231 (291) Show / Hide
Range on Protein: 237-449
Range on HMM: 1-231/291
Sequence Identity: 27% (68 aa)

FSENNKIGEGSYGHVYKGTLHRTN-----VAVKVLRHDSWQGPQE-------FEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGG---NPEKK
. .  .||.||.| |.||. . ..     ||||  |..     ..       ||.|.|.| ..|.  |              || |. ..|.   .| . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNN--------------HPCIIQFYGVCLQPPCHF

CLVYEYLENGSLEDRLFCKDDSPP-----------ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLD------KNYNSKISDVGLARFMPG
|.| ||.|.||| . |  ... .            ..     ..|. .  .. .||. .|.||. ||||..|||.|      .. . ||.| |..|..  
CIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQ

D-ETSVRSTSPVGTFAYIDPEY--Q-REGSFNAKSDVFAFGIILLQLLT
  ..    .|  ||.|.  ||   | |.. .. |.||. .|..| ..||
MCTN---MMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLT

Kinase IRAK-Un_df.AA LRRK 237-449 23 9.7e-34 116.73 In-house 1-277 (351) Show / Hide
Range on Protein: 237-449
Range on HMM: 1-277/351
Sequence Identity: 23% (69 aa)

FSENNKIGEGSYG-HVYKGTLHR----------------------------TNVAVKVLRHD---------------------SWQGPQEFEQEVRKLTR
. ....||.|..|  ||.... .                            ..||.|..  |                     | |.    .|. . ..|
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

I-SKISNEHGKIKVEVLSRLHHPHIVLLLGGNPEKKCLVYEYLENGSLEDRLFCKDDSP------PISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLK
. ..  .|     | ..|.|.||.|| |.|   .  |.| ||. .|.| ..|. |  ..       ||  ....||...  .. .||...| ||. ||||
AFREFRHE-----VWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNP-PIIHRDLK

PSNILL---D---------KNYNSKISDVGLARFMPGDETSVRST---SPVGTFAYIDPEYQREG---SFNAKSDVFAFGIILLQLLT
. ||||   .          ... ||.| |. | |    ......     ||.. .  ||  |..   ... |.|...||.||  |||
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF---QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLT

Kinase IRAK-Un_df.AA Pkinase 237-453 27 1.7e-30 108.91 Pfam 1-211 (293) Show / Hide
Range on Protein: 237-453
Range on HMM: 1-211/293
Sequence Identity: 27% (63 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGN--PEKKCLVYEYLENG-
.    |||.||.| |||.. . |.  ||||... .  . ... .. .|                .... ||.||.|| |..    . . ..| ||.|.| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRL-------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL

---SLEDRLFCKDDSPPI--SCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS----KISDVGLARFMPGDETSVRSTSPVGTFAYID
   .| |..   ... ..  |  .   .. ..  .| ..|.     |. |||||.|||.|.|..     ||.| |||...     ..  |...||  |. 
YVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMA

PEYQR-EGSFNAKSDVFAFGIILLQLLTATSP
||  |       |.|....|.|| ..|.   |
PEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP

Kinase IRAK-Un_df.AA RIPK 243-453 27 2e-26 87.04 In-house 1-227 (290) Show / Hide
Range on Protein: 243-453
Range on HMM: 1-227/290
Sequence Identity: 27% (67 aa)

IGEGSYGHVYKGT--LHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGNPEK--------KCLVYEYLENGS
.| |. | |.| .   ... ||.|.      . .   .||. .. .  |. .           .| . ||| ..|   ..          .| || ||||
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMYQKEEAKHMH-----------KLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGS

LEDRLFCKD--DSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--ET---------SVRSTSPVGTFA
|.. |  |     .|.    |  . .|.  .  .||  .| ||  |||||.|||.| |.. ||.| ||| .| .    .         | .|  . || .
LWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLHSMNP-PIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLS

YIDPEYQREGSFNA------KSDVFAFGIILLQLLTATSP
|..||  |..  ..      |.||  |.|.. ..||   |
YMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase IRAK-Un_df.AA TKL-Unique 299-444 29 1.2e-24 84.0 In-house 46-218 (290) Show / Hide
Range on Protein: 299-444
Range on HMM: 46-218/290
Sequence Identity: 29% (52 aa)

VEVLSRLH-HPHIVLLLGGNP----EKK--CLVYEYLENGSLEDRLF-------CKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNIL
| ....|| || ||.. |.        .  |.| ||.. ||| | |           .. ... . |...|  .  .. .||  .|  |  ||||.||.|
VNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFL

LDKN-----YNSKISDVGLARFMPGDETSVRS-------TSPVGTFAYIDPEYQRE--GSFNAKSDVFAFGIIL
.| |     .| ||.|.||..|   . ..  .       ....|.| .. ||  |     .. ||||..|||.|
VDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL

Kinase IRAK-Un_df.AA Dicty4 299-449 29 5.6e-24 77.0 In-house 49-212 (277) Show / Hide
Range on Protein: 299-449
Range on HMM: 49-212/277
Sequence Identity: 29% (48 aa)

VEVLSRLHHPHIVLLLGG------NPEKKCLVYEYLENGSLEDRLFC------KDDSPPISCLTR-YQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILL
|. .. . ||.|.|..|       .|.| | | ||.  |.|.  |        . .... .  .|  ..|  .   .  ||   |  |. ||||..|.| 
VHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV-IIHRDLKSHNLLV

DKNYNSKISDVGLAR-FMPGDETSVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLT
|||.. |..| ||.. . .. . .   ....|| ..  ||  .. ..| |.||. |||.| ..||
DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILT

Kinase IRAK-Un_df.AA CZAK 237-453 28 1.3e-23 82.66 In-house 1-221 (279) Show / Hide
Range on Protein: 237-453
Range on HMM: 1-221/279
Sequence Identity: 28% (67 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQE-FEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLG----GNPEKKCLVYEYLENG
.     ||.| .| |||.    . ||.| .  ..     |  | ..          .|     | ..| | || .|  ||    ..|. .| | |. . |
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENM--------FQKE-----VSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGG

SLEDRLFCKDDSPPISC--LTRYQIAVEVGTALLFLHK-AKPQPIVLRDLKPSNILLDKNYN-------------SKISDVGLARFMPGDETSVRSTSPV
||  | .  | .  .      . ..|. .     .||   || ||. |||  .||||| .|               ||.| || | |   |     |. .
SL--RRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREM--MEQPFEMTQTM

GTFAYIDPEYQREGSFNAKSDVFAFGIILLQLLTATSP
|  ..  ||     ..  |.||. ||.||  ..|   |
GCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQP

Kinase IRAK-Un_df.AA TK 237-449 18 2.6e-23 74.36 In-house 1-389 (486) Show / Hide
Range on Protein: 237-449
Range on HMM: 1-389/486
Sequence Identity: 18% (72 aa)

FSENNKIGEGSYG---HVYKGTLHR---------------------------TNVAVKVLRHDSWQGPQEFEQ-EVRKLTRISKISNEHG------KIKV
    .|.||| .|    ||||....                           | ||||.|. .. . ..||.. | .   |      . |          
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHD--R-D----G-GEDFLEEAEEM

EVLS--RLHHPHIVLLLG----GNP----------EKKCLVYEYLENGS----LEDRLF-----------------------------------------
....   .|||.|| |.|    | |          |  ..| || ..|.    | | |                                          
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

------------CKDDSPPISCLTRYQ-------------------IAVEVGTALLFLHKAKP---QPIVLRDLKPSNILLDKNYN-----------SKI
             ||..||..    .|                   ... .  .. .||. .    | .| |||   |.|...|..            ||
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKI

SDVG--------LARFMPGDETSVRSTSPVGT------------------------FAYIDPEYQREGS---------FNAKSDVFAFGIILLQLLT
.| |        ||| .. |.  .|..|. ..                        . .  ||  ...          |  ||||..||. .  ..|
ADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase IRAK-Un_df.AA S_TKc 237-521 22 1.2e-19 72.57 SMART 1-231 (231) Show / Hide
Range on Protein: 237-521
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FSENNKIGEGSYGHVYKGTLHR--TNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRLHHPHIVLLLGGNP-EKKCLVYEYLEN--G
.   .|||.|..| |||.. ..    ||.|...                         || .  ...|.. |||.|| |..    .. ..| ||...  |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLG

SLEDRLFCKDDSPP---ISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGDETSVRSTSPVGTFAYIDPEYQRE
.| |..  .   ..   ..  .   .. ..  || ..|. .   |. |||||.|||||.  . ||.| ||||..         |. .||  |. ||    
DLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--

GSFNA-KSDVFAFGIILLQLLTATSPVGIIHKVSTAVDQGHLMEILDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQ-MLETMNHLFR
 ...  |.|. ..|.||  .|.   |           ..  .....             ..  .  .| ..  ..||    .||  .. ..| . 
-GYGKCKCDWWSCGCILYEMLCGYPPFP---------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAK-Un_df.AA TyrKc 237-513 22 1.8e-16 43.77 SMART 1-280 (280) Show / Hide
Range on Protein: 237-513
Range on HMM: 1-280/280
Sequence Identity: 22% (69 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQEFEQEVRKLTRISKISNEHGKIKVEVLSRL--HHPHIVLLLGG--NP-------EKKCLVY
 . . |.||| .| |||||.  ..||||.|..|.                .  . .|      .....|  |||.|| |.|    .       |  ..| 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----------------REDFMRE-----ARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVM

EYLENGSLEDRL-FCKDDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNSKISDVGLARFMPGD--------ETSVRS--TSP
|| ..|.| |.|  ....   ..  .  .... .     .||.    ... |||   |.|...|.  |||| ||.|.   |          ....   . 
EYMPHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGK

-VGTFAYIDPEYQREGSFNAKSDVFAFGIIL--LQLLTATSPVG------IIHKVSTAVDQGHLMEILDT-----SAGEWPLAAATQLACIGLNCAEVQR
 .       ||  ..| |. ||||..||. .  .  . .. . |          |   |.||. |.. .      .       . . .  | . | . . 
TMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-----VCCPDEMYQIMKQCWHEDP

KNRPELENVLQML
..||  ... . .
EDRPTFSEIHECF

Kinase IRAK-Un_df.AA CAMK 373-453 23 2.4e-13 38.64 In-house 200-333 (425) Show / Hide
Range on Protein: 373-453
Range on HMM: 200-333/425
Sequence Identity: 23% (32 aa)

IVLRDLKPSNILLDKN-----------------YNSKISDVGLARFMPGDETSV---------------------RSTSPVGTFAYID-PEYQR------
|| ||||| |||||.|                 .| ||.| |.|......| .                        . ..|| .|.  ||  .      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------EGSFNAKSDVFAFGIILLQLLTATSP
        .   . |.|. . |.||  .|. ..|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPP

Kinase IRAK-Un_df.AA CAMK 242-338 16 4.4e-13 37.8 In-house 1-152 (425) Show / Hide
Range on Protein: 242-338
Range on HMM: 1-152/425
Sequence Identity: 16% (27 aa)

KIGEGSYGHVYKGTLHRTN--------------VAVKVLRHD-------------------------SW---QGPQEFEQEVRKLTRISKISNEHGKIKV
..|.||.| |....  .|.              ||.|..  .                         .|   .  .....|.. . ....|.|       
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGN-------

EVLSRLHHPHIVLLLG--------------GNPEK--------KCLVY---EYLENGSLEDRLF
    .|.||.|. |.                . .|         ..|    || ..| | |.||
----KLDHPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLF

Kinase IRAK-Un_df.AA IRAK 237-267 45 1.6e-10 33.63 In-house 1-33 (317) Show / Hide
Range on Protein: 237-267
Range on HMM: 1-33/317
Sequence Identity: 45% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTN--VAVKVLR
|...|.|||| .| ||.| .. |   .||| |.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLK

Kinase IRAK-Un_df.AA Pkinase_Tyr 237-288 27 1.9e-09 32.65 Pfam 1-62 (270) Show / Hide
Range on Protein: 237-288
Range on HMM: 1-62/270
Sequence Identity: 27% (17 aa)

FSENNKIGEGSYGHVYKGTLH------RTNVAVKVLRHDSWQG---PQEFEQEVRKLTRI-S
 . . |.|||..|.|||||..      .. ||||.|.... .     ..| .|.. .. . .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH

Kinase IRAK-Un_df.AA TKL-Unique 241-282 44 2.1e-08 25.92 In-house 3-47 (290) Show / Hide
Range on Protein: 241-282
Range on HMM: 3-47/290
Sequence Identity: 44% (20 aa)

NKIGEGSYGHVYKGTLHRTNVAVKVLRHDSWQGPQ---EFEQEVR
||||||.|| ||||. ... ||.|..   . . ..   ||| ||.
NKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVN

Kinase IRAK-Un_df.AA Dicty4 237-266 50 5.1e-08 23.01 In-house 1-30 (277) Show / Hide
Range on Protein: 237-266
Range on HMM: 1-30/277
Sequence Identity: 50% (15 aa)

FSENNKIGEGSYGHVYKGTLHRTNVAVKVL
    ..||.||.| |||||   . ||||.|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKL

Kinase IRAK-Un_df.AA Pkinase_Tyr 299-442 28 1e-06 22.87 Pfam 54-202 (270) Show / Hide
Range on Protein: 299-442
Range on HMM: 54-202/270
Sequence Identity: 28% (44 aa)

VEVLSRL-HHPHIVLLLGGNP--EKK---CLVYEYLENGSLEDRLFCK-DDSPPISCLTRYQIAVEVGTALLFLHKAKPQPIVLRDLKPSNILLDKNYNS
..... | |||.|| |.|     ..    ..| || ..|.| | |  . .| .|..  .  |.....  .. .|.  .   .. |||   |.|...|   
AKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVV

KISDVGLARFM-PGDET-SVRSTSPVGTFAYIDPEYQREGSFNAKSDVFAFGI
||.| |||| . . |.   .|. ..        ||  ..| |. |||| .||.
KICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSDVWSFGV

Kinase IRAK-Un_df.AA IRAK 473-513 17 0.067979 2.7 In-house 277-317 (317) Show / Hide
Range on Protein: 473-513
Range on HMM: 277-317/317
Sequence Identity: 17% (7 aa)

LDTSAGEWPLAAATQLACIGLNCAEVQRKNRPELENVLQML
.|  .. .| . .  ...  . |..   ..|.. . |.| |
IDHRMPPCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL