IRAKa_c-1

Species: S.moellendorffii
Alias: IRAKa_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKa

Sequence

Name Sequence Type Origin Length Description Download
IRAKa_c-1.AA Protein None 757 None Fasta, JSON
IRAKa_c-1.NA RNA None 2274 None Fasta, JSON
IRAKa_c-1.kin_dom Protein Kinase Domain None 202 None Fasta, JSON

Protein domain

Protein domains of IRAKa_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKa_c-1.AA TKL 448-711 22 3.6e-65 222.84 In-house 1-364 (364) Show / Hide
Range on Protein: 448-711
Range on HMM: 1-364/364
Sequence Identity: 22% (86 aa)

LGKGAFGTVYKGVLEN---------GQAVAIKRASI----SSTRSS-----------------------ELFEKELQLLTRTHHSCLVNLVGYCMEEK--
.|.|.||.||||.. .         |. ||.|. ..    ..|..|                       . .|.|. .. |..|  .| ..|||....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------LLVFEFMSRGSLYDNIFARSGPSTGLQWICRIKLAAQAARGLEYLHKYAC-----PPIIHRDVKSANILLDDEWN------------
              .| |....|||....           |  |...| ..|||..|||         ||||||| ||.|||.|. |.            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--AHVSDFGLSLFGPLGSATHLS----------------NMTIVGTPGYLDPEYGFFM----------------KLTTKSDVYSFGVVLLELLSGQKPVD
  . ..||||| |    .    .                .||..|||... ||    .                . ..|.||||||.|| |.|....| .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

--HFRPVQ------NIVIWAKELLNDDTLH-----QLFDPALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAKSL
  ...|..       . ... .  .  ..       .     . .  |  . . .||. .| |   . |||.. . | |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH---K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase IRAKa_c-1.AA IRAK 442-645 35 2.6e-59 203.38 In-house 1-225 (317) Show / Hide
Range on Protein: 442-645
Range on HMM: 1-225/317
Sequence Identity: 35% (80 aa)

YSEEMVLGKGAFGTVYKGVLENGQ-AVAIK----RASISSTRSSELFEK---ELQLLTRTHHSCLVNLVGYCMEEKL--LVFEFMSRGSLYDNIFARSGP
.... ..|.|.||.||.|.. |    .|.|     |..| . . . |     ||....| .|  .| | ||| |.    ||...|. ||| |   .. | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

STG--LQWICRIKLAAQAARGLEYLHKYA-CPPIIHRDVKSANILLDDEWNAHVSDFGLSLFG-PLG--SATHL---SNMTIVGTPGYLDPEYGF--FMK
 .   | |. |.. .  .|.|...||    | ||||.|.||||||||.  ..  .||||  || | .   .. .      ...||  |. ||.    . .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

LTTKSDVYSFGVVLLELLSGQKPVD
||.|.||||||.||||.|.|...|.
LTKKTDVYSFGIVLLEVLTGCRAVY

Kinase IRAKa_c-1.AA LRRK 442-647 25 1e-43 151.55 In-house 1-286 (351) Show / Hide
Range on Protein: 442-647
Range on HMM: 1-286/351
Sequence Identity: 25% (74 aa)

YSEEMVLGKGAFG-TVYKGVLEN---------------------------GQAVAIKRASIS----------------------------------STRS
  .|  .|.|.|| .||.. ...                           .| ||||   .                                   ..|.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

SELFEKELQLLTRTHHSCLVNLVGYCMEEKLLVFEFMSRGSLYDNIFARSGPS-----TGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILL
  .| .|. .. . .|...|.|.|.|..   .| |... |.||. .....  .     . . |  ..|.| | |.|.||||. . ||||||| || ||||
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNILL

---D---------DEWNAHVSDFGLSL-FGPLGSA-THLSNMTIVGTPGYLDPEYGFFM---KLTTKSDVYSFGVVLLELLSGQ-KPVDHF
   .         .. .|...|||.|  | ..... .    .. ||.||.. ||   ..     |.|.|.||||..| |||..|  | |..
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVA----KGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEH

Kinase IRAKa_c-1.AA TKL-Unique 447-643 32 2.8e-42 146.77 In-house 4-233 (290) Show / Hide
Range on Protein: 447-643
Range on HMM: 4-233/290
Sequence Identity: 32% (76 aa)

VLGKGAFGTVYKGVLENGQAVAIKRASI---SSTRSSELFEKELQLLTRTH-HSCLVNLVGYCM----EEK--LLVFEFMSRGSLYDNIF---ARS---G
..| |..|.||||.  .|  ||||. ..   || .... ||.|. .. . | |  .| ..||||     ..   .| |....|||||..      .    
KIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNN

PSTGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDE-----WNAHVSDFGLSLFGPLGSATHLSNM------TIVGTPGYLDPEYGFFM
... | .  |.|.| ..|.|..||| .  | ||||| || |.|.| .     ||. ..||||| |    ... ...       | .|.. .. ||  . |
NNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV-LRM

---KLTTKSDVYSFGVVLLELLSGQK------P
   . ..||||||||.|| |.....       |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP

Kinase IRAKa_c-1.AA Pkinase 442-641 28 6.6e-39 138.64 Pfam 1-209 (293) Show / Hide
Range on Protein: 442-641
Range on HMM: 1-209/293
Sequence Identity: 28% (61 aa)

YSEEMVLGKGAFGTVYKGVLENGQA-VAIKRASISSTRSSELFEK----ELQLLTRTHHSCLVNLVGYCMEEKLLV--FEFMSRG----SLYDNIF-ARS
|  . ..|.|.||.|||..  . .  ||.|. . ....|... ..    |.|.. | .| . | | ....... .   .|..  |    .|.| |   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GPSTGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNA----HVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGF-FMKLTTK
|. . ...   .. . | .|||||.|.     |||||.|..|||.|.. .     ...||||. .          ..|..|||.|. ||      . ..|
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVYSFGVVLLELLSGQ
.|..|.|..| |.|.|.
VDMWSCGCILYEMLCGR

Kinase IRAKa_c-1.AA MLK 442-643 29 1.9e-36 124.02 In-house 1-235 (291) Show / Hide
Range on Protein: 442-643
Range on HMM: 1-235/291
Sequence Identity: 29% (70 aa)

YSEEMVLGKGAFGTVYKGVLENGQ----AVAIKRASI------SSTRSSELFEKELQLLTRTHHSC----LVNLVGYCMEE-K--LLVFEFMSRGSLYDN
  .. ..|.|.|| |.||.  |       ||.||. .      ..  ... ||.|  .| .  |       . ..| | .. .  ..| |... ||||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IFA-RSGPS---------TGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDD------EWNAHVSDFGLSLFGPLGSATHLSNMTI-VGT
. . ||...                 .. | | |||..|||. | .|||||| || |||.|.      . .. ..|||.| .    . .. .||.   ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRD---WHQMC-TNMMSNAGT

PGYLDPEY---GFFMKLTTKSDVYSFGVVLLELLSGQKP
. .  ||        | . |.||.|.|||| |.|... |
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase IRAKa_c-1.AA TK 442-643 17 4e-36 118.04 In-house 1-394 (486) Show / Hide
Range on Protein: 442-643
Range on HMM: 1-394/486
Sequence Identity: 17% (68 aa)

YSEEMVLGKGAFG---TVYKGVLENG--------------------------QAVAIKRASISSTRSSELFEK-----------------ELQLLT--RT
   . .||.|.||   .|||| ....                          . ||.|     .. |.| |.                  |....     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHSCLVNLVGYCMEEK--------------LLVFEFMSRGS----LYDNIFARSGPSTG-----------------------------------------
||  .|.|.|.|....              ..| |.|. |.    | |   ..... .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LQWICRIKLAAQAARGLEYLHKYAC---PPIIHRDVKSANILLDDEWN-----------AHVSDFGLS-
                               |   ...  ..|.|.|.||||.  |   . ..|||.   |.|.... .           . ..||||| 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LFGPLGSATHLSNMTIVGTPG-------------------------YLDPEYGF---------FMKLTTKSDVYSFGVVLLELLS-GQKP
     |   ..| .    ..  ||..                         .. ||  .         . | ||||||.||||.. |... ||.|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

Kinase IRAKa_c-1.AA S_TKc 442-715 24 2.1e-34 121.55 SMART 1-231 (231) Show / Hide
Range on Protein: 442-715
Range on HMM: 1-231/231
Sequence Identity: 24% (71 aa)

YSEEMVLGKGAFGTVYKGVLEN-GQAVAIKRASISSTRSSELFEKELQLLTRTHHSCLVNLVGYCM-EEKLLVFEFMSR--GSLYDNIFARSGPSTG--L
|    ..||||||.|||..  . |. ||||. .       | ...|.|.| . ||  .|.| ...  ..  .|.|...   |.|.| |  | .. ..  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

QWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGFFMKLTT-KSDVYSFGVVL
      ....| ...|||.|.     |||||.| .|||||.  .  ..||||. .           .|..||| |. ||     . .. |.|..|.|..|
PE-HARFYMYQICCALEYCHSH-G--IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELLSGQKPVDHFRPVQNIVIWAKELLNDDTLHQLFDPALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAK-----SLEDIL
 |.|.|. | .      ..    | ..                        |  .   | ..  . ||.   . .      .   .
YEMLCGYPPFP------QMQMMFKKIG---------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAKa_c-1.AA Dicty4 442-655 33 2.4e-34 112.07 In-house 1-229 (277) Show / Hide
Range on Protein: 442-655
Range on HMM: 1-229/277
Sequence Identity: 33% (79 aa)

YSEEMVLGKGAFGTVYKGVLENGQAVAIKRA--SISSTRSSEL--FEKELQLLTRTHHSCLVNLVGYCM------EEKLLVFEFMSRGSLYDNIFA---R
.  |  .|||.||.||||    |..||.| .       ....|  | ||  ..    |  .. . |.|       .. . | |.|..|.||  . .    
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

SGPSTGLQWICRIK---LAAQAARGLEYLHKYAC--PPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVGTPGYLDPEYGFFMKLTT
  .|. |.|. ...   .|  ||||. .||   |  | ||||| ||.|.| |. |.. |.|||||     ..      || .|||..  ||   .   . 
QQQSIKLDWPLIKRAMRMAFDAARGMNWLH---CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNE

KSDVYSFGVVLLELLSGQKPVD-HFRPVQNIVI
|.|||||| || |.| .| |   |..|  ..|.
KADVYSFGIVLWEILTRQEPYQKHHMPYMQFVR

Kinase IRAKa_c-1.AA Dicty4-Unclassified 445-643 32 7.8e-30 99.34 In-house 4-207 (263) Show / Hide
Range on Protein: 445-643
Range on HMM: 4-207/263
Sequence Identity: 32% (69 aa)

EMVLGKGAFGTVYKGVLENGQAVAIKRASISSTRSS----ELFEKELQLLTRTHHSCLVNLVGYCMEE------KLLVFEFMSRGSLYDNIF---ARSGP
   .|||.|  |.||.   |  ||.|     . .      . | ||  .|    |  || . |||.           | ||| .| |   |    .    
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

STGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATHLSNMTIVG-TPGYLDPEYGFFMKLTTKSDVYSF
.  |     || |   |.|. .||      .||||.||.|||.|   |. . |||.|            ||| .. ||    ||       . ||||||.
PIKLDDTLIIKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRV-----IDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GVVLLELLSGQKP
...| ||. |  |
AMMLYELATGDEP

Kinase IRAKa_c-1.AA STE 442-641 23 9.5e-30 102.28 In-house 1-265 (359) Show / Hide
Range on Protein: 442-641
Range on HMM: 1-265/359
Sequence Identity: 23% (64 aa)

YSEEMVLGKGAFGTVYKGVLEN----------------GQAVAIKRASISST-----------------RSSELFEKELQLLTRTH--HSCLVNLVGYCM
.    ..||||||||||..  .                |. .|||. ....                     . ..||.... . .  |   |.  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---------EEKLLVFEFMSRGSLYDNIFARSGPSTG------------LQWICRIKLAAQAARG-LEYLHKYACPPIIHRDVKSANILLDDEWNAHVSD
         .|  .. |.|. ||| | |  . |.  .             ..|..|  . |  .| |.|||.     |||||.|.|||||     .  .|
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYI--CRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCD

FGLSL-FGPLGS------------ATHLSNMTIVGTPGYLDPEY--GFFMK----LTTKSDVYSFGVVLLELLSGQ
||..  . . ..             .   . |.|||| .  ||   .   .     .||.|..|.| ...|.. |.
FGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase IRAKa_c-1.AA RIPK 448-643 25 2.1e-29 97.32 In-house 1-227 (290) Show / Hide
Range on Protein: 448-643
Range on HMM: 1-227/290
Sequence Identity: 25% (58 aa)

LGKGAFGTVYKGVLENGQAVAIKRASISSTRS-------SELFEKELQLLTRTHHSCLVNLVGYCMEE--------KLLVFEFMSRGSLYDNIFARSG-P
.|.|.||.|.| .      ...| .. .  .        ..    | . . .  ..  | . | | .|          .| |.|  ||| .   ...   
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

STGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLGSATH--------LSNMTIV--GTPGYLDPEYGF--FM
   . |  |  .  . ..|  |||    ||||||| | .|||.| . .. ..||||. .    . .         .|       ||  |..||  .    
HHPDPWPLRCRMIHEISCGMCYLHSMN-PPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

KL----TTKSDVYSFGVVLLELLSGQKP
|     |.|.|||||..|. |.|.. .|
KPIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase IRAKa_c-1.AA Pkinase_Tyr 442-588 27 9.3e-29 98.02 Pfam 1-158 (270) Show / Hide
Range on Protein: 442-588
Range on HMM: 1-158/270
Sequence Identity: 27% (45 aa)

YSEEMVLGKGAFGTVYKGVLE-----NGQAVAIKRASISSTRS---SELFEKELQLLTRT-HHSCLVNLVGYCM--EEK---LLVFEFMSRGSLYDNIFA
 .   .||.||||.||||..      ... ||.|    ... .   .| | .|.....   ||  .|.|.| |.  .|    ..|.|.|  |.|.|   .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R--SGPSTGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLS
.  ....  ...   .. ..| |.|.|||.      .||||.   |.|....  . ..||||.
HREDKQPLTMKD--LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLA

Kinase IRAKa_c-1.AA TyrKc 442-711 24 1.2e-24 89.08 SMART 1-280 (280) Show / Hide
Range on Protein: 442-711
Range on HMM: 1-280/280
Sequence Identity: 24% (75 aa)

YSEEMVLGKGAFGTVYKGVLENGQAVAIKRASISSTRSSELFEKELQLLTRT--HHSCLVNLVGYCM---------EEKLLVFEFMSRGSLYDNIFARSG
 . . .|| ||||.||||..   . ||.|    ..    | | .|......   || ..|.|.|.|.         |  ..|.|.|. |.| | . .. .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

PSTGLQWICRIKLAAQAARGLEYLHKYACPPIIHRDVKSANILLDDEWNAHVSDFGLSLFGPLG-------SATH-----LSN--MTIVGTPGYLDPEYG
    |..   .. . |.|.| ||||.    ..||||    |.|....  . .|||||| ..  .       .  .      ..  . |  ..    ||  
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA----PECI

FFMKLTTKSDVYSFGVVLLELLS-GQKPVDH---FRPVQNIVIWAKELLNDDTLHQLFD--PALAVPEMPEPLYRAAKLALECTDVRGKMRPSMTNVAKS
.. | ||||||.||||.. |... ||.|        .. |. . .. . . . . |  .  | .. ...|. .|   .. ..| .   ..||..... . 
NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEY-VKQGYRMPQPPNDYP-MSFVCCPDEMY---QIMKQCWHEDPEDRPTFSEIHEC

L
.
F

Kinase IRAKa_c-1.AA Pkinase_Tyr 617-643 50 1e-06 23.24 Pfam 187-214 (270) Show / Hide
Range on Protein: 617-643
Range on HMM: 187-214/270
Sequence Identity: 50% (14 aa)

FFMKLTTKSDVYSFGVVLLELLS-GQKP
...| ||||||.||||.. |... |..|
NYGKFTTKSDVWSFGVLMWEIFTYGEQP

Kinase IRAKa_c-1.AA IRAK 689-711 30 0.006496 6.36 In-house 295-317 (317) Show / Hide
Range on Protein: 689-711
Range on HMM: 295-317/317
Sequence Identity: 30% (7 aa)

LALECTDVRGKMRPSMTNVAKSL
.|..|.  | . |..|. | ..|
CACCCGHHRANRRCDMAWVMQQL