Gene IRAKb_e (S.moellendorffii)

IRAKb_e

Species: S.moellendorffii
Alias: IRAKb_e
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKb

Sequence

Name Sequence Type Origin Length Description Download
IRAKb_e.AA Protein None 408 None Fasta, JSON
IRAKb_e.NA RNA None 1227 None Fasta, JSON
IRAKb_e.kin_dom Protein Kinase Domain None 199 None Fasta, JSON

Protein domain

Protein domains of IRAKb_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKb_e.AA IRAK 107-307 34 3.4e-58 199.67 In-house 1-223 (317) Show / Hide 
Range on Protein: 107-307
Range on HMM: 1-223/317
Sequence Identity: 34% (78 aa)

FSPGNFLAEGGYGPVYRGILKDGR-YIAVK---RNKDASTQG-EKEFKA---EVEALSGAQHRNLVTLLGFCIEGGKRILVYEFVCNKCLDWHLSAAN-T
|...| . |||.| |||| .|      |||    ..| |. . ...| .   |.....  .| |.| |.|.|.|...  |||..  |  |   |.. . .
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

NV---LPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARW----QSNDDSAA---QT-RLVGTLGYLAPEYIS--SGE
.    |.|  |. .. |.|.....||.     .| |.|. . ||||  . ||| .||||.|     ... ..      | ...||. |..||.|   .|.
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VTTKTDVYSFGVVLLELITGRRA
 |.||||||||.||||..||.||
LTKKTDVYSFGIVLLEVLTGCRA
Kinase IRAKb_e.AA TKL 113-306 21 4.1e-51 176.13 In-house 1-287 (364) Show / Hide 
Range on Protein: 113-306
Range on HMM: 1-287/364
Sequence Identity: 21% (64 aa)

LAEGGYGPVYRGILKD---------GRYIAVKRNKDASTQGEKE-------------------------FKAEVEALSGAQ--HRNLVTLLGFCIEGGK-
. .||.| ||.|...          |. .|||. |  . . . .                         |. |.|...  .  | |.| ..|.|..... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYEFVCNKC-LDWHLSAANTNVLPWSARHAVAVGAARALRYLHE----GCRTG-SIVHRDVRPHNILLTHDYT------------
              .|.|.. . . |. ..         |. |.  | ..||.. |||     .|.    |.|||  ..|||.  ..|            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PKVGDFGLARWQ----SNDDSA--------------AQTRLVGTLGYLAPEYIS----------------SGEVTTKTDVYSFGVVLLELITGRR
  .|..||||.|.     .. |..              .  . .||....||| .                 ..| ..|.||||||.|| |..|..|
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR
Kinase IRAKb_e.AA Pkinase 107-305 24 1.6e-34 123.11 Pfam 1-209 (293) Show / Hide 
Range on Protein: 107-305
Range on HMM: 1-209/293
Sequence Identity: 24% (53 aa)

FSPGNFLAEGGYGPVYRGILKDGRY-IAVKRNKDASTQGEKEFKA-----EVEALSGAQHRNLVTLLGFCIEGGKRILVYEFVCNK----CLDWHLSAAN
.  |  . .|..| ||... |. .   |||. |   .. ... ..     |.. .   .| | |.|.... ....  .| |.. .      |  ..|. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

TNVL--PWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTP----KVGDFGLAR-WQSNDDSAAQTRLVGTLGYLAPEYIS-SGEVTTK
 ...  ..     ..   .|.| |.|. .   .|.|||. | |||. .....    |..|||||.  . .  .   | ..||..|.||| |  . . ..|
HGCFYFSEWECKFYMYQILRGLEYCHS-M---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

TDVYSFGVVLLELITGR
 |..|.|..| |...||
VDMWSCGCILYEMLCGR
Kinase IRAKb_e.AA TK 107-303 16 6.3e-34 110.55 In-house 1-389 (486) Show / Hide 
Range on Protein: 107-303
Range on HMM: 1-389/486
Sequence Identity: 16% (64 aa)

FSPGNFLAEGGYG---PVYRGILKDGR--------------------------YIAVKRNKDASTQGEKEFKA--------------EVEALSGAQ----
   |. | || .|    ||.|......                            |||  |. ... ..||..              |.|...  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVTLLGFCIEG------------GKRILVYEFVCNKC----LDWHLSAA-----------------------------------------------
 | |.| |.| | .|            .  ..| |.... .    |. .| .                                                
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------------------------NTNVLPWSARHAVAVGAARALRYLHEG-CRTG--SIVHRDVRPHNILLTHDYT-----------PKVGDFG--
                           ... |.   ..  .. .|....|||.  |. .   .||||.  .|.|......            |..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARWQSNDDSAAQTRLVGTLG-------------------------YLAPEYISSGE---------VTTKTDVYSFGVVLLELIT
      |||   .||    ..  || .                         ..||| . ...          |||.||.||||.. |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKb_e.AA MLK 107-305 25 1.6e-31 106.7 In-house 1-233 (291) Show / Hide 
Range on Protein: 107-305
Range on HMM: 1-233/291
Sequence Identity: 25% (61 aa)

FSPGNFLAEGGYGPVYRGILKDGR----YIAVKRNK----DASTQG--EKEFKAEVEALSGAQHRN----LVTLLGFCIEGGK-RILVYEFVCNKCLDWH
.    .. .|..| |..|  .  .     .|||| .    |.|  .   ..|. |.. |.  .|.|     . ..| |.. ..   .| |.. . .|   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LSAANT----------NVLPWSARHAV--AVGAARALRYLHEGCRTGSIVHRDVRPHNILLTH------DYTPKVGDFGLARWQSNDDSAAQTRLVGTLG
| .|..          |    .  ||.  |.  ||.. |||.  .   |.|||  .||||...      . | |. |||..|  .. . .  .   ||. 
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPK-PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLAPEYI---SSGEVTTKTDVYSFGVVLLELITGR
. ||| |    .. .. | ||.|.|||| |..|..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKb_e.AA TKL-Unique 109-304 26 4.1e-31 107.04 In-house 1-224 (290) Show / Hide 
Range on Protein: 109-304
Range on HMM: 1-224/290
Sequence Identity: 26% (61 aa)

PGNFLAEGGYGPVYRGILKDGRYIAVKRNK-DASTQGE--KEFKAEVEALSGAQ-HRNLVTLLGFCI----EGGKRILVYEFVCNKCLDWHLSA------
..| . |||||.||.|. . |  .|.|. .  ..   |  .||. ||  ..  . | |.|.. |.|.      .....| |..    |. .|.       
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--ANTNVLPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHD-----YTPKVGDFGLARWQSNDDSAAQTRL--------VGTLGYLAPEY
  .| . |... |   |  .|... |||    .  | ||| .. |.|.. .     .  |. ||||.. .|...    ...        .|.. ..||| 
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

ISS--GEVTTKTDVYSFGVVLLELITG
...     ..| ||||||.|| |..|.
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKb_e.AA Pkinase_Tyr 107-303 28 4.4e-31 105.91 Pfam 1-209 (270) Show / Hide 
Range on Protein: 107-303
Range on HMM: 1-209/270
Sequence Identity: 28% (60 aa)

FSPGNFLAEGGYGPVYRGILK-----DGRYIAVKRNKDASTQGE---KEFKAEVEALSGA-QHRNLVTLLGFCI-EGGK--RILVYEFVCNKCLDWHLSA
 . |  | || .| ||.|..|     ..   |||  |. ... .   ..| .|.. ..   .| |.| |.| |. .|.    ..| |.... .|. .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

A--NTNVLPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQ-SNDDS-AAQTRLVGTLGYLAPEYISSGEVTTKTD
   . . |. .     ..  |... ||..      ..|||..  |.|.|.. . |..||||||   . |    ...        .||| |. |. |||.|
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGVVLLELIT
|.||||.. |..|
VWSFGVLMWEIFT
Kinase IRAKb_e.AA S_TKc 107-377 20 1.7e-30 108.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 107-377
Range on HMM: 1-231/231
Sequence Identity: 20% (59 aa)

FSPGNFLAEGGYGPVYRGILKD-GRYIAVKRNKDASTQGEKEFKAEVEALSGAQHRNLVTLLGFCIEGGKRILVYEFVCN--KCLDWHLSAANTNV----
.  .. . .|..| ||... |. ||. |.|. |       . .. |.. |.  .| |.|.|.... . ..  .| |.. .    | ...   ...     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQSNDDSAAQTRLVGTLGYLAPEYISSGEVTT-KTDVYSFGVVL
.|      ..   ..|| |.|.      |.|||. | ||||..  . |..||||||          | ..||. |.||| .     .. | |..|.|..|
FPE-HARFYMYQICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELITGRRAINLSLPAGETSLIEWARPMIETREAESLIDKRLGDKFNMYELHCMIHAASFCLRAAPSERATMSQVCV---------CL
 |...|.          .  ...  .                         . ...  . ||.  |..| |  ..            .
YEMLCGYPPFP-----QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKb_e.AA TK-Unique 107-303 25 1.8e-28 95.36 In-house 1-234 (294) Show / Hide 
Range on Protein: 107-303
Range on HMM: 1-234/294
Sequence Identity: 25% (61 aa)

FSPGNFLAEGGYGPVYRGILKD-------GRYIAVKRNKDASTQGE-KEFKAEVEALSGAQ-HRNLVTLLGFCIEGG-KRILVYEFVCNKCLDWHLS---
.  |. . || .|.|.|| ..         . .||| .|| .|. . ..|. | . ..    | |.|..|| |.. .    ...|.. . .|. .|    
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

AA-----------------NTNVL--PWSARHAV--AVGAARALRYLHE---GCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQSNDDSAAQTRL-
 |                 .  ..  | | .  .  |.. |... ||..   ..     ||||.  .|.|||.|.. |..|||.||  ..    .. .  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI-----VHRDLCARNVLLTEDKVCKICDFGMARDVYT--NGVYSMMC

---VGTLGYLAPEYIS--SGEV-TTKTDVYSFGVVLLELIT
      . ..|||...   |   |||.||.||||.. |. |
SQGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAKb_e.AA LISK 112-307 24 2.4e-26 82.45 In-house 1-238 (296) Show / Hide 
Range on Protein: 112-307
Range on HMM: 1-238/296
Sequence Identity: 24% (60 aa)

FLAEGGYGPVYRGILK-DGRYIAVKRNKD-----ASTQGEKEFKAEVEALSGAQHRNLVTLLGFCIE-GGKRILVYEFVCNKCLDWHLSAAN--TNVLPW
 . .|..| ||.| .. .|. .|.| ..           .| .. ||. .   .|.| |   | | .  |.  .| |..   .| . |.. .    .|||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

SARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLT----HDYTPKVGDFGLARWQSNDD----------------------------SAAQTRL--
. |   |.. |....|||. .    |.|||   .|.|.      ... ||.|||.||  . ..                            . . .|   
PQRVKIALDIACGMSYLHSMN----IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRR

---VGTLGYLAPEYISSGEVTTKTDVYSFGVVLLELITGRRA
   .||    ||| .   . ... ||.|||.||.|.||...|
MTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVKA
Kinase IRAKb_e.AA TyrKc 107-377 23 8.9e-26 92.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 107-377
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

FSPGNFLAEGGYGPVYRGILKDGRYIAVKRNKDASTQGEKEFKAEVEALSGA--QHRNLVTLLGFCIEG-------GKRILVYEFVCNKCLDWHLSAANT
 . |  | || .| ||.|..|  .  |||  |. .   ...|  | . ..    .| |.| |.| |...       .   .| |.... .|. .| .   
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

NVLPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQSND-------DSAA-----QTRLVGTLGYLAPEYISSGEV
. |...  .  .. .|.  .|||.      ..|||    |.|.....| |..||||.|   .|       |        ... .  .  .||| |  |. 
K-LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TTKTDVYSFGVVLLELITGRRAINLSLPAGETSLIE---WARPMIETREAESLIDKRLGDKFNMY--------ELHCMIHAASFCLRAAPSERATMSQVC
|||.||.||||.. |. |           |..   .       |.. .|.  .....   .   .            |    . | .. |..| |.|...
TTKSDVWSFGVCMWEIFTY----------GQQPYPGMIQQ---MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIH

VCL
 |.
ECF
Kinase IRAKb_e.AA LRRK 107-307 21 1e-25 87.93 In-house 1-282 (351) Show / Hide 
Range on Protein: 107-307
Range on HMM: 1-282/351
Sequence Identity: 21% (62 aa)

FSPGNFLAEGGYG-PVYRGILKD--------------------GRYIAVKRNKDASTQGEK---------------------------------------
.  .. . .||.| .|||.....                    .|  . .... | .. ..                                       
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

--EFKAEVEALSGAQHRNLVTLLGFCIEGGKRILVYEFVCNKCLDWHLSAAN-TN------VLPWSARHAVAVGAARALRYLHEGCRTGSIVHRDVRPHN
  ||  ||  .|. .| |.| |.||||.   ...| |.. .  |. .|..   .       ...|. .. .|.  |....|||   .. .|.||| ...|
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS--HNPPIIHRDLKSPN

ILL-TH-----------DYTPKVGDFGLAR-WQSNDDSAAQTRLVGTLGYLAPEYISSG---EVTTKTDVYSFGVVLLELITGR-RA
||| ..           ... |..|||. | . . . ...  ..||. |..||| .  .   | |.|.|.||||..| ||.|.. ..
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase IRAKb_e.AA STE 207-305 28 1.4e-19 65.94 In-house 155-265 (359) Show / Hide 
Range on Protein: 207-305
Range on HMM: 155-265/359
Sequence Identity: 28% (34 aa)

AVAVGAARA-LRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQSND-------------DSAAQTR--LVGTLGYLAPEYISS------GE
....   .. | |||.      |.|||. | ||||      |  |||..   ...             .. .| |  .|||  . ||| |.       ..
YICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKG

VTTKTDVYSFGVVLLELITGR
 .|| |..|.| ...|..||.
YDTKCDIWSLGCTIIEMATGK
Kinase IRAKb_e.AA Dicty4-Unclassified 207-304 31 8.6e-17 54.0 In-house 113-204 (263) Show / Hide 
Range on Protein: 207-304
Range on HMM: 113-204/263
Sequence Identity: 31% (31 aa)

AVAVGAARALRYLHEGCRTGSIVHRDVRPHNILLTHDYTPKVGDFGLARWQSNDDSAAQTRLVGTLGYLAPEYISSGEVTTKTDVYSFGVVLLELITG
..|   |. . .||    |  ..|||..  |||.  ..  |..|||..|  ..      |   ||    .||       . | ||||....| ||.||
KYAFDIAQGMQHLH----TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFN--FNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATG
Kinase IRAKb_e.AA Dicty4-Unclassified 111-171 35 1.1e-07 22.37 In-house 5-68 (263) Show / Hide 
Range on Protein: 111-171
Range on HMM: 5-68/263
Sequence Identity: 35% (23 aa)

NFLAEGGYGPVYRGILKDGRYIAVKRNKDASTQGE----KEFKAEVEALSGAQHRNLVTLLGFCI
 |. .|    |..|. | |. .|||   . . .      ..||.||| |   || |||.. | ||
QFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCI
Kinase IRAKb_e.AA STE 107-189 12 2e-06 18.78 In-house 1-125 (359) Show / Hide 
Range on Protein: 107-189
Range on HMM: 1-125/359
Sequence Identity: 12% (16 aa)

FSPGNFLAEGGYGPVYRGILKD----------------GRYIAVK--RNKDAST---------------QGEKEFKAEVEALSGAQ--HRNLVTLLGFCI
.    .. .|..| ||... ..                |...|.|  . .. ..               . ..... |.. ..  .  | | |. .| ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EGG-------KRILVYEFVCNKCLD
 .|       .  .. |.. . .||
KEGHNHKNDDELWICMEYMDGGSLD
Kinase IRAKb_e.AA TK 359-377 36 0.029018 2.53 In-house 468-486 (486) Show / Hide 
Range on Protein: 359-377
Range on HMM: 468-486/486
Sequence Identity: 36% (7 aa)

CLRAAPSERATMSQVCVCL
| .. |..| |.||.  .|
CWHYDPEDRPTFSQLHEQL
Kinase IRAKb_e.AA Pkinase_Tyr 359-377 31 3.098978 1.42 Pfam 252-270 (270) Show / Hide 
Range on Protein: 359-377
Range on HMM: 252-270/270
Sequence Identity: 31% (6 aa)

CLRAAPSERATMSQVCVCL
| .. |..| |.|..  .|
CWHYDPEDRPTFSEIHEQL