Gene IRAKd_b-2 (S.moellendorffii)

IRAKd_b-2

Species: S.moellendorffii
Alias: IRAKd_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKd

Sequence

Name Sequence Type Origin Length Description Download
IRAKd_b-2.AA Protein None 809 None Fasta, JSON
IRAKd_b-2.NA RNA None 2430 None Fasta, JSON
IRAKd_b-2.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of IRAKd_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 IRAKd_b-2.AA LRR_1 156-178 40 8.6e-05 21.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 156-178
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLELLNLSS-N--FLSGSIPDR-FSSL
.|. |.||. |   |.|.||.. | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 180-202 33 1.848226 5.8 Pfam 1-26 (26) Show / Hide 
Range on Protein: 180-202
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLQSLALDN-N--ILRGTFPTA-LNVL
.||.| |.. |   | |..|   .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 204-226 33 0.057646 11.14 Pfam 1-26 (26) Show / Hide 
Range on Protein: 204-226
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLDTLQLSH-N--QIAGTIPSQ-ISLF
|| .| ||. |  .. |.||.  .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 228-250 33 0.004731 14.99 Pfam 1-26 (26) Show / Hide 
Range on Protein: 228-250
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLKTLDMDH-N--LLFGALPDS-ISNM
.|..||... |   | | .|.| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 254-273 20 66.42954 0.28 Pfam 3-26 (26) Show / Hide 
Range on Protein: 254-273
Range on HMM: 3-26/26
Sequence Identity: 20% (5 aa)

ETISISD-N--FLAGVVPN--LSRV
.....|. |   | | .|.  .   
QHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 275-287 41 1.173137 6.5 Pfam 1-17 (26) Show / Hide 
Range on Protein: 275-287
Range on HMM: 1-17/26
Sequence Identity: 41% (7 aa)

SLRTLNLAG-N--QL-G
.|..|.| | |  .| |
NLQHLDLSGCNCCNLTG
LRR_1 IRAKd_b-2.AA LRR_1 296-318 25 0.130653 9.88 Pfam 1-26 (26) Show / Hide 
Range on Protein: 296-318
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

GLVSANLER-N--RFSDSIPDS-LRGL
 | . .| . |  .....||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 320-342 29 1.188473 6.48 Pfam 1-26 (26) Show / Hide 
Range on Protein: 320-342
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLKLLNLSL-N--SIPGALPGW-IFSL
.|. |.||  |  .. | .| . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 344-365 29 0.020263 12.75 Pfam 1-26 (26) Show / Hide 
Range on Protein: 344-365
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLETLVLDH-N--RLSGTLPS--AVTL
.|..| |.. |  .|.|..|.     |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKd_b-2.AA LRR_1 368-390 25 11.758445 2.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 368-390
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

GLRYVDIST-N--LLMGEVPAE-LRSG
 |.. |.|  |   | |..| . . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase IRAKd_b-2.AA TKL 531-786 18 1.2e-36 128.03 In-house 1-364 (364) Show / Hide 
Range on Protein: 531-786
Range on HMM: 1-364/364
Sequence Identity: 18% (70 aa)

IGEGEYGKVFRGKLDD---------GTLVAIKCLVI---------------------------DSRQEMKQLKAHLEFLSRIRHRHLVSLFGYCLEREKD
||.| .|.|..||.           |. ||.| . .                           ..........  .  .||.|| ..|.. |||.. ...
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

G------PQHRRLYLVSEFIDNGTLRSHLFKRKLKESLTWQNRLVAALGAGRGIHYLHTGVV-----PGIFNNDVRVTNVLLDHNFV-------------
.       .   |..| |....|.|...|          |. |.  ||.. ||..|||.        |.|   |    |.|.| |.              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-GKVSDFGLAR-HPESES-------------YQSYGSDLATDKR------------------------------------DVYNFGLILLEIVLGRPPTV
  |..||||.| . .|..             .|  ..     ..                                    ||| ||..| ||. ...|  
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQ-NNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY

DNP----MAMKPKVQELVSSSSSVFRTEMVDSAISG----TCSEDSLSTVLEIAAKCLSSDLTARPSMEDVLWNL
|.|    ....| ..|  .  .. ..   ...  .      . .| .  . ... .| ..| ..|||....|  |
DYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKd_b-2.AA IRAK 525-690 29 1.7e-35 123.31 In-house 1-174 (317) Show / Hide 
Range on Protein: 525-690
Range on HMM: 1-174/317
Sequence Identity: 29% (53 aa)

FSQGLLIGEGEYGKVFRGKLDDGT-LVAIK----CLVIDSRQEMKQLKA---HLEFLSRIRHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRSH
|.....||||..| |.||...  |  .|.|       .   . .... .    |. ..|.|| ..|.| |||.||..       . || ... ||.|.  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQC-------HCLVYPYMPNGSLEDR

LFKRKLKES---LTWQNRLVAALGAGRGIHYLHTGV--VPGIFNNDVRVTNVLLDHNFVGKVSDFGLARHP---ESESYQSY
|  ..   .   |.|. |.  ..|...||..||.    .| |   |.   |.||| .|. | .||||.|..   ..  .|.|
LWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIH-GDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTY
Kinase IRAKd_b-2.AA TK 525-687 14 3.2e-21 67.19 In-house 1-314 (486) Show / Hide 
Range on Protein: 525-687
Range on HMM: 1-314/486
Sequence Identity: 14% (46 aa)

FSQGLLIGEGEYG---KVFRGKLDDG--------------------------TLVAIKCLVIDSRQEMKQLKA-----------------HLEFLS--RI
   |  .|||..|   .|..|.. ..                          | ||.|.|  .. ..... ..                  .. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHRHLVSLFGYCLEREKDGPQH-----RRLYLVSEFIDNGT----LRSHLFKRKLKES------------------------------------------
.| ..|.|.|.|.. |   .       . ...| |. ..|     ||..| |.. |..                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTWQNRLVAALGAGRGIHYLHTG----VVPGIFNNDVRVTNVLLDHNFV-----------GKVSDFG--
                               || . .|  .. . .|  |||      . ...   |.   |.|...| |            |..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARHPESESY
      |||  .|...
RQGSGVLARDIYSDDD
Kinase IRAKd_b-2.AA TKL-Unique 527-680 29 3.6e-21 71.51 In-house 1-165 (290) Show / Hide 
Range on Protein: 527-680
Range on HMM: 1-165/290
Sequence Identity: 29% (50 aa)

QGLLIGEGEYGKVFRGKLDDGTLVAIKCLVI--DSRQEMKQ-LKAHLEFLSRIR-HRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRSHLF----
 . .||||.||.|..||   |. |||| . .  ||. ||.| .. ..  ..... |  .| ..|||    .. ..  ....|.|... |.|...|     
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCM---DHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

-----KRKLKESLTWQNRLVAALGAGRGIHYLHTGVVPGIFNNDVRVTNVLLDHN-----FVGKVSDFGLAR
     ....|  |..|.|.  |. . .| .|||.   | |   | . .|.|.| |     .  |..||||..
NNNNNNNNCK--LNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSK
Kinase IRAKd_b-2.AA Pkinase_Tyr 525-646 24 1.3e-19 67.06 Pfam 1-128 (270) Show / Hide 
Range on Protein: 525-646
Range on HMM: 1-128/270
Sequence Identity: 24% (32 aa)

FSQGLLIGEGEYGKVFRGKLD-----DGTLVAIKCLVIDSRQE---MKQLKAHLEFLSRI-RHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRS
 . |  .|||..|.|..|...     ... ||.|.|  .. .|   .. . . .. .. . .| ..|.| | |.  ....|.  ..|.| |.  .| |..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCT--DQGEPN--QIYIVMEYMPHGDLLD

HLFKR-KLKESLTWQNRLVAALGAGRGIHYLH
.| |.   |..|| .  |  ..   .|  ||.
YLRKHREDKQPLTMKDLLQMCWQIAKGMEYLE
Kinase IRAKd_b-2.AA LISK 530-680 28 1e-17 53.96 In-house 1-153 (296) Show / Hide 
Range on Protein: 530-680
Range on HMM: 1-153/296
Sequence Identity: 28% (46 aa)

LIGEGEYGKVFRGKLD-DGTLVAIKCLVI-----DSRQEMKQLKAHLEFLSRIRHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRSHLFKRKL-
 ||.| .|||..| .  .|. .||| . .     . .   | ..  .. . ..||.. |  .| | .        ..|..| |.|. |.|.  |..... 
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYH------NDGQLHIVTEYINGGDLHQYLKDMDKH

KESLTWQNRLVAALGAGRGIHYLHTGVVPGIFNNDVRVTNVLLDHN----FVGKVSDFGLAR
|  |.|. |.  ||.  .|  |||     .|.  |   .|.|.. |    .  || |||.||
KIPLPWPQRVKIALDIACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFAR
Kinase IRAKd_b-2.AA TyrKc 525-786 19 2e-15 26.74 SMART 1-280 (280) Show / Hide 
Range on Protein: 525-786
Range on HMM: 1-280/280
Sequence Identity: 19% (61 aa)

FSQGLLIGEGEYGKVFRGKLDDGTLVAIKCLVIDSRQEMKQLKAHLEFLSRI--RHRHLVSLFGYCLEREKDGPQH---RRLYLVSEFIDNGTLRSHLFK
 . |  .|||..|.|..|...  . ||.|.|  |.   .. .   .. ....  .| ..| |.|.|.. .           |..| |. ..| |...| |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN---FMYIEPLMIVMEYMPHGDLKDYLRK

RKLKESLTWQNRLVAALGAGRGIHYLHTGVVPGIFNNDVRVT-------NVLLDHNFVGKVSDFGLARHPESE-------SYQSY----GSD--L-----
.. |  |...  |  .. . .|  |||            ..        |.|...|.. |.|||||.|  ...       .| .     |..  |     
HRPK--LCMKDLLSFCWQIACGMEYLHSK----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

---ATDKR------DVYNFGLILLEIV-LGRPPTVD---NPMAMKPKVQELVSSSSSVFRTEMVDS-----AISGTCSEDSLSTVLEIAAKCLSSDLTAR
   . ...      ||. ||  . ||  .| .|  .   .    . . ||..    . .| .  ..         .|...    . .|  .|   |   |
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----MMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDE----MYQIMKQCWHEDPEDR

PSMEDVLWNL
|.....   .
PTFSEIHECF
Kinase IRAKd_b-2.AA UTK 525-680 23 1.7e-14 46.01 In-house 1-176 (296) Show / Hide 
Range on Protein: 525-680
Range on HMM: 1-176/296
Sequence Identity: 23% (43 aa)

FSQGLLIGEGEYGKVFRGKLDDGT------LVAIKCLV--IDSRQEMK---QLKAHLE---FLSRIR-HRHLVSLFGYCLEREKDGPQHRRLYLVSEFID
  .| ..|.|..| |....... .      .||.| ..   |..||.    ..  .     .... . |.... | |.|.  |        ...|.|.  
VQLGRQLGQGAFGEVHKARFTQCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEP-------WMIVTEYME

NGTLRSHLF--KRKLKESLTWQN---RLVAALGAGRGIHYLHTGVVPGIFNNDVRVTNVLLDHN-------FVGKVSDFG---LAR
|| ||| |   .... .  .|..   ||  |.   || .|||.    |.  .|.   |.|....        | |..|||   ..|
NGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSC---GFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSR
Kinase IRAKd_b-2.AA CAMK 530-627 10 3.5e-13 38.1 In-house 1-181 (425) Show / Hide 
Range on Protein: 530-627
Range on HMM: 1-181/425
Sequence Identity: 10% (19 aa)

LIGEGEYGKVFRGKL-DDG------------TLVAIKCLVID----------------------------SRQEMKQLKAHLEFLSR-------IRHRHL
 .|.| .|||....   ..            . |||| .  .                            . . .|... ..| ...       ..|...
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VSLFGYCLEREK--------DGPQ-----HRRLYLVS---EFIDNG----TLRSHLFKR----------------KLKESLT
..|. .   ...           .      ...|.|    |....|     | ... ..                ...|. .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREA
Kinase IRAKd_b-2.AA S_TKc 525-789 20 7.7e-13 11.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 525-789
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

FSQGLLIGEGEYGKVFRGKLDD-GTLVAIKCLVIDSRQEMKQLKAHLEFLSRIRHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDN--GTLRSHLFKRK
.  . .||.| .|||....  . | .||||..        ....  .. |.. .| ..| |.... .         .||.| |..|.  |.|.... ||.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--------DHLYMVMEYCDGDLGDLFDYIKKRG

-------LKESLTWQNRLVAALGAGRGIHYLHTGVVPGIFNNDVRVTNVLLDHNFVGKVSDFGLARHPESESYQSYGSDLAT------------D-KRDV
       . |  ..      .    ... |.|     ||   |.   |.|||.  . |..||||||.          .   |              | |.
RHGLRFPFPE-HARF----YMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVLGYGKCKCDW

YNFGLILLEIVLGRPPTVDNPMAMKPKVQELVSSSSSVFRTEMVDSAISGTCSEDSLSTVLEIAAKCLSSDLTARPSMEDVLW------NLQYA
. .| || | . |.||   ....|  |.                             . ....  |||  | . ||.  ..|       . .. 
WSCGCILYEMLCGYPPFP-QMQMMFKKIG---------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKd_b-2.AA Pkinase 525-624 17 1.1e-12 45.92 Pfam 1-107 (293) Show / Hide 
Range on Protein: 525-624
Range on HMM: 1-107/293
Sequence Identity: 17% (20 aa)

FSQGLLIGEGEYGKVFRGKLDDG-TLVAIKCLVIDSRQEMKQLKA----HLEFLSRIRHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNG----TLRS
.  |  ||.| .|.|....  .   .||.|..  ... . |.  .     .. . |..| . | |.... .       ....|.| |. ..|     | .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-------KDHIYMVMEYCEGGLYVMDLFD

HLF---KRKL--KE
..    ....   |
YISTWRHGCFYFSE
Kinase IRAKd_b-2.AA TK-Unique 525-617 20 5.9e-12 37.63 In-house 1-96 (294) Show / Hide 
Range on Protein: 525-617
Range on HMM: 1-96/294
Sequence Identity: 20% (21 aa)

FSQGLLIGEGEYGKVFRGKLDDGT-------LVAIKCLVIDSRQE-MKQLKAHLEFLSRIR-HRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRS
.  | .||||..| |.||..  ..        ||.| | ......  ....  ..... .  | ..|...|.| . .       . ... |.. .|.|..
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSD------EPWMIIMEYCPCGNLQH

HL
.|
YL
Kinase IRAKd_b-2.AA STE 525-615 15 6.4e-12 38.5 In-house 1-126 (359) Show / Hide 
Range on Protein: 525-615
Range on HMM: 1-126/359
Sequence Identity: 15% (20 aa)

FSQGLLIGEGEYGKVFRGKLDD----------------GTLVAIKCLVIDS-----------------RQEMKQLKAHLEFLSRIR--HRHLVSLFGYCL
.     ||.| .|.|....  .                |...||| . ...                  .||.|..  ...... .  | . |  .|...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EREKDGPQHR--RLYLVSEFIDNGTLRS
   ..  ..    |... |..|.|.|..
KEGHN--HKNDDELWICMEYMDGGSLDD
Kinase IRAKd_b-2.AA Src-Echino1 526-687 27 1.4e-11 35.92 In-house 2-151 (252) Show / Hide 
Range on Protein: 526-687
Range on HMM: 2-151/252
Sequence Identity: 27% (45 aa)

SQGLLIGEGEYGKVFRGKLDDGTLVAIKCLVIDSRQEMKQLKAHLEFLSRIRHRHLVSLFGYCLEREKDGPQHRRLYLVSEFIDNGTLRSHLFKRKLK-E
     ||.|..| |..|  .  | ||.| |   .     .. |  . . ..||. .| ..  | ..|        .|.| | . || |...| . | |  
RMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKT-MSPADFLAEANVMKKCRHEGIVQIYAVCSDKEP-------IYIVTELMSNGNLQDYLKRGKCKHV

SLTWQNRLVAALGAGRGIHYLHTGVVPGIFNNDVRVTNVLLDHNFVGKVSDFGLARHPESESY
 .|    . | . .  |. ||    |      |.   |||...  | |. ||||||  . . |
KMTTLIDMGAHIAS--GMDYLGSKNV---VHRDLAARNVLVGKGNVCKIADFGLARMMQKDVY
Kinase IRAKd_b-2.AA TK-Unique 662-681 55 0.00019 11.39 In-house 163-182 (294) Show / Hide 
Range on Protein: 662-681
Range on HMM: 163-182/294
Sequence Identity: 55% (11 aa)

NVLLDHNFVGKVSDFGLARH
|||| ...| |..|||.||.
NVLLTEDKVCKICDFGMARD
Kinase IRAKd_b-2.AA Pkinase 662-690 27 0.002139 13.09 Pfam 138-171 (293) Show / Hide 
Range on Protein: 662-690
Range on HMM: 138-171/293
Sequence Identity: 27% (10 aa)

NVLLDHNFVG----KVSDFGLAR---HPESESYQSY
|.|.|.| .     |..|||||.   .  .. ....
NILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTF
Kinase IRAKd_b-2.AA Pkinase_Tyr 662-680 57 0.002545 11.87 Pfam 141-159 (270) Show / Hide 
Range on Protein: 662-680
Range on HMM: 141-159/270
Sequence Identity: 57% (11 aa)

NVLLDHNFVGKVSDFGLAR
|.|...|.| |..||||||
NCLVTENNVVKICDFGLAR
Kinase IRAKd_b-2.AA IRAK 696-786 18 0.006538 6.35 In-house 202-317 (317) Show / Hide 
Range on Protein: 696-786
Range on HMM: 202-317/317
Sequence Identity: 18% (22 aa)

TDKRDVYNFGLILLEIVLGRPPTVDN---PMAMKPKVQELVSSSSS-----------------------VFRTEMVDSAISGTCSEDSLSTVLEIAAKCL
| | ||| ||. |||.. |... .|.   .   | ...|. .. ..                         .   .|. ... | ...    .  |  |.
TKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPP-CPPNMEKEMCQCACCCG

SSDLTARPSMEDVLWNL
   .  |..|. |.  |
HHRANRRCDMAWVMQQL
Kinase IRAKd_b-2.AA LISK 700-720 38 0.013461 4.03 In-house 221-241 (296) Show / Hide 
Range on Protein: 700-720
Range on HMM: 221-241/296
Sequence Identity: 38% (8 aa)

DVYNFGLILLEIVLGRPPTVD
||. || .|.||. .. .. |
DVFSFGIVLCEIITRVKADPD
Kinase IRAKd_b-2.AA UTK 760-786 25 0.015377 4.51 In-house 270-296 (296) Show / Hide 
Range on Protein: 760-786
Range on HMM: 270-296/296
Sequence Identity: 25% (7 aa)

TVLEIAAKCLSSDLTARPSMEDVLWNL
.| ..  .|  .|   ||..||..  .
PVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase IRAKd_b-2.AA CAMK 662-681 27 0.054643 1.39 In-house 209-245 (425) Show / Hide 
Range on Protein: 662-681
Range on HMM: 209-245/425
Sequence Identity: 27% (10 aa)

NVLLDHN-----------------FVGKVSDFGLARH
|.|||.|                 .  |..|||.|..
NILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANK
Kinase IRAKd_b-2.AA TK 763-786 20 0.069776 1.23 In-house 463-486 (486) Show / Hide 
Range on Protein: 763-786
Range on HMM: 463-486/486
Sequence Identity: 20% (5 aa)

EIAAKCLSSDLTARPSMEDVLWNL
..  .| . |   ||......  |
DLMQQCWHYDPEDRPTFSQLHEQL