Gene IRAKg_f (S.moellendorffii)

IRAKg_f

Species: S.moellendorffii
Alias: IRAKg_f
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKg

Sequence

Name Sequence Type Origin Length Description Download
IRAKg_f.AA Protein None 636 None Fasta, JSON
IRAKg_f.NA RNA None 1911 None Fasta, JSON
IRAKg_f.kin_dom Protein Kinase Domain None 60 None Fasta, JSON

Protein domain

Protein domains of IRAKg_f.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKg_f.AA B_lectin 65-144 27 1.3e-14 51.8 Pfam 1-107 (137) Show / Hide 
Range on Protein: 65-144
Range on HMM: 1-107/137
Sequence Identity: 27% (30 aa)

LKTIVWTAPAA---PSVAFTA---NARLQLTA-QG-LFVSDGA---QL--ITIA-NVPS-VA--S---AELQDNGNFVVI-SSSG--S---WQS--FDVP
 .|.||.|       .|  ..   |..|....  | | ..||.   .   .  . |. |  .  .   |..||.||.|.  . ..  .   |||  || |
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDD-NNDSNNVLWQSNTFDHP

TDTLLTGQ
|||.| |.
TDTWLPGM
B_lectin IRAKg_f.AA B_lectin 25-136 27 1.1e-11 46.01 SMART 1-126 (126) Show / Hide 
Range on Protein: 25-136
Range on HMM: 1-126/126
Sequence Identity: 27% (36 aa)

GDVLAVNQFLVSPDNTFE--LGFVDDEASGKFTLVIRFHHIN--LKTIVWTA-PAAPSVAFT--ANARLQLTAQG-LFVSDGAQLI--TIAN-VPSVASA
  .|  .|.|||.. .||  |||.  . .  ... | ...|.   .|.|| | |   . .    ....| ..  | | . |  . .  .  . . .. .|
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ--WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD-NRPVWSSNTTRNNGNYVA

ELQDNGNFVVISSS--GS----WQSFDVP
.|||.||||.....   |    ||||| |
VLQDDGNFVIYDPDDNDSGNFIWQSFDHP
S_locus_glycop IRAKg_f.AA S_locus_glycop 238-297 30 4.6e-10 36.65 Pfam 55-114 (117) Show / Hide 
Range on Protein: 238-297
Range on HMM: 55-114/117
Sequence Identity: 30% (18 aa)

RLTLERNGTLRVYSLTQDNSSWNIVWQALTADCKVFGMCGPFGICTYRPGLVCTCPPGFH
|.|.  .|.| ..  . .. .||  | | .  | . ..|||.|.|      .|.| .||.
RFTMSSEGYLQRFTWNPNSQDWNLFWYAPKDQCDYYRRCGPYGYCDMNTSPMCNCIKGFV
PAN_AP IRAKg_f.AA PAN_AP 319-403 22 1.3e-08 35.81 SMART 1-85 (85) Show / Hide 
Range on Protein: 319-403
Range on HMM: 1-85/85
Sequence Identity: 22% (20 aa)

GSDNRWVRLERTDYTYNDKT-----YISVISLEDCKSLCKENCGCLGIAYRADGSGQCFLKGPDSTRGPKQVIYNGFQIASGPNLFFLKV
..|. .||.... .  .. .      | |.|||.|...| .|| | ...| .  ...| |   ||  |  . .   .. ...   .. |.
CCDDCFVRMPNMKL--FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN--TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
PAN_1 IRAKg_f.AA PAN_1 317-374 19 3.5e-08 28.62 Pfam 1-56 (84) Show / Hide 
Range on Protein: 317-374
Range on HMM: 1-56/84
Sequence Identity: 19% (12 aa)

CNGSDNRWVRLERTDYTYNDKTYISVI-SLEDCKSLCKENCG--CLGIAYRADGSGQCFLK
|..  . ..| . ... .. .  .. . |.|.| ..| .| .  |  . |  . ..||.|.
CHR--WHFERHPNYIL-GH-IWVMKNVDSAEECQQKCQNNPRFTCRSFTYNYK-TKQCHLH
Kinase IRAKg_f.AA TKL-Unique 504-564 34 2.9e-11 36.14 In-house 1-65 (290) Show / Hide 
Range on Protein: 504-564
Range on HMM: 1-65/290
Sequence Identity: 34% (23 aa)

FKDKLGTGGFGTVFKGLLPDGIIVAVKNIEM--EIQAE--KQFQAEVTTLGNIH-HINLVRLLGYS
|  |.|.||.|.|.||  . |..||.| ..   ..  |  . |  ||... ..| |.|.|.. ||.
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYC
Kinase IRAKg_f.AA Pkinase_Tyr 504-562 34 1e-10 36.92 Pfam 3-71 (270) Show / Hide 
Range on Protein: 504-562
Range on HMM: 3-71/270
Sequence Identity: 34% (24 aa)

FKDKLGTGGFGTVFKGLLP-----DGIIVAVKNI--EMEIQA--EKQFQAEVTTLGNI-HHINLVRLLG
|  ||| | ||.|.|| .      ..| |||| .      ..   . | .|. .. .. || |.|||.|
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYG
Kinase IRAKg_f.AA IRAK 503-564 33 2.3e-10 33.07 In-house 1-72 (317) Show / Hide 
Range on Protein: 503-564
Range on HMM: 1-72/317
Sequence Identity: 33% (24 aa)

FFKD-KLGTGGFGTVFKGLLPDGI-IVAVK----NIEMEI-QAEKQFQA---EVTTLGNIHHINLVRLLGYS
| || ..| ||||.|..| .     |.|||    . .|.. . ...||.   |. ..  ..| |.| |.||.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYC
Kinase IRAKg_f.AA Src 504-561 31 4.5e-10 30.38 In-house 3-60 (255) Show / Hide 
Range on Protein: 504-561
Range on HMM: 3-60/255
Sequence Identity: 31% (18 aa)

FKDKLGTGGFGTVFKGLLPDGIIVAVKNIEMEIQAEKQFQAEVTTLGNIHHINLVRLL
...|||.| || |..|.  . . |||| .     . ..|..|  .. .  | .||.|.
LCRKLGQGQFGEVWMGYWNGNTKVAVKTLKPGTMSPEAFLQEAQIMKKLRHEKLVQLY
Kinase IRAKg_f.AA ULK 502-561 21 1.3e-09 29.87 In-house 1-84 (329) Show / Hide 
Range on Protein: 502-561
Range on HMM: 1-84/329
Sequence Identity: 21% (18 aa)

NFFKDKLGTGGFGTVFKGL-LPD----GIIVAVKNIE---MEIQAEK--------QFQAEVTTLGNIH----HIN----LVRLL
   ...|| | ||.|.||    .    ...||.| |.   | ..           ... |. ..  ..    |.|     |.|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLY
Kinase IRAKg_f.AA Abl 503-562 34 1.3e-09 27.67 In-house 2-62 (252) Show / Hide 
Range on Protein: 503-562
Range on HMM: 2-62/252
Sequence Identity: 34% (21 aa)

FFKDKLGTGGFGTVFKGLLPD-GIIVAVKNIEMEIQAEKQFQAEVTTLGNIHHINLVRLLG
  |.||| | .| |..|.    . .|||| .  .  . ..| .|   . ...| |||.|||
MMKHKLGGGQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLG
Kinase IRAKg_f.AA ULK 502-561 22 1.5e-09 30.12 In-house 1-81 (324) Show / Hide 
Range on Protein: 502-561
Range on HMM: 1-81/324
Sequence Identity: 22% (18 aa)

NFFKDKLGTGGFG-TVFKGL-LPD---GIIVAVKNIE---MEIQAEK--------QFQAEVTTLGNIH---HIN--LVRLL
   ...|| | || .|.||    .   . .||.| |.   | ..  .        ... |. ..  ..   | |   |.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLY
Kinase IRAKg_f.AA EGFR 505-562 36 2.1e-09 27.23 In-house 4-68 (258) Show / Hide 
Range on Protein: 505-562
Range on HMM: 4-68/258
Sequence Identity: 36% (24 aa)

KDKLGTGGFGTVFKGL-LPDG----IIVAVKNI--EMEIQAEKQFQAEVTTLGNIHHINLVRLLG
  .|| | ||||.||.  |.|    | ||.| .  . . .| . .  | . .. . | .||||||
VKVLGSGAFGTVYKGIWIPEGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLG
Kinase IRAKg_f.AA STE 504-563 19 4.4e-09 28.34 In-house 1-98 (359) Show / Hide 
Range on Protein: 504-563
Range on HMM: 1-98/359
Sequence Identity: 19% (19 aa)

FKD--KLGTGGFGTVFKGLLPD----------------GIIVAVKNIEMEI------------------QAEKQFQAEVTTLGNIH--HINLVRLLGY
...  |.| |.||||.|..  .                | |.|.| ...|                   . ..|.. |. .. . .  | | |. .|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGC
Kinase IRAKg_f.AA TKL 508-564 22 1.3e-08 27.16 In-house 1-94 (364) Show / Hide 
Range on Protein: 508-564
Range on HMM: 1-94/364
Sequence Identity: 22% (21 aa)

LGTGGFGTVFKGLLPD---------GIIVAVKNIEM---------------------------EIQAEKQFQAEVT-TLGNIHHINLVRLLGYS
.| ||||.|.|| .           |  |||| . .                           |.. ...|  |..  . ...| |.|...||.
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYC
Kinase IRAKg_f.AA Dicty2 506-563 33 6.3e-08 23.86 In-house 6-71 (264) Show / Hide 
Range on Protein: 506-563
Range on HMM: 6-71/264
Sequence Identity: 33% (22 aa)

DKLGTGGFGTVFKGL-LPDGIIVAVKNIE----MEIQAEKQF---QAEVTTLGNIHHINLVRLLGY
.|.| |.||||.|||   .|  || | |.      .. |.|     .|.  | .  | | |. ...
EKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEH
Kinase IRAKg_f.AA Pkinase 504-563 30 7.3e-05 18.28 Pfam 3-68 (293) Show / Hide 
Range on Protein: 504-563
Range on HMM: 3-68/293
Sequence Identity: 30% (20 aa)

FKDKLGTGGFGTVFKGLLPDG-IIVAVKNIEMEIQAEKQFQA-----EVTTLGNIHHINLVRLLGY
.. |.| |.||.|.|.   .  .||||| |. . . ... |.     |.  . ...| | |||...
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDW
Kinase IRAKg_f.AA TyrKc 502-631 12 0.000194 -150.85 SMART 1-280 (280) Show / Hide 
Range on Protein: 502-631
Range on HMM: 1-280/280
Sequence Identity: 12% (36 aa)

NFFKDKLGTGGFGTVFKGLLPDGIIVAVKNIEMEIQAEKQFQAEVTTLGNI--HHINLVRLLGYSGQSR------KNHKR-----DHGARNSRIHGTGM-
  ...||| | ||.|.|| .   | |||| .  .   .. |  |   . ..  || |.|||.|.  |.       . .       .||. ..... ..  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

--------------------------------------GPQ----------RHHYSK----------------GGR------------------------
                                       ..          | .|..                ||.                        
LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDV

--------------VQLWHG-------PLRAAEWRKNNSSRWRSCH--------------------------------ELGTRAF
               | . |       . .. |. |.   . .  .                                |.  . |
WSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF