Gene IRAKg_k-2 (S.moellendorffii)

IRAKg_k-2

Species: S.moellendorffii
Alias: IRAKg_k-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKg

Sequence

Name Sequence Type Origin Length Description Download
IRAKg_k-2.AA Protein None 683 None Fasta, JSON
IRAKg_k-2.NA RNA None 2052 None Fasta, JSON
IRAKg_k-2.kin_dom Protein Kinase Domain None 130 None Fasta, JSON

Protein domain

Protein domains of IRAKg_k-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKg_k-2.AA B_lectin 83-192 31 9.6e-28 96.91 Pfam 1-137 (137) Show / Hide 
Range on Protein: 83-192
Range on HMM: 1-137/137
Sequence Identity: 31% (46 aa)

EFIPIWIANRD---TPV-----TSNASLLLTS-KGELQIIDRG---SI--IWSG--APSSSNS-GITQAVLLDSGNFVLT-D--NAFDPRDDNATYPWQS
.  . | ||||   .||     ..|..| ...  | | . | |   |.  .||     |.|.|   . |...||||.||  |  .       . .. |||
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNND-------SNNVLWQS

--FDHPADAWVPRMKMFL------GAN----LTAWKSSV--SPA
  |||| | | | ||. .      ..|    ||.|||.    |.
NTFDHPTDTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin IRAKg_k-2.AA B_lectin 38-166 29 1.7e-23 85.26 SMART 1-126 (126) Show / Hide 
Range on Protein: 38-166
Range on HMM: 1-126/126
Sequence Identity: 29% (40 aa)

SSLLTTESLISANGRVK---LEFFSPTGGNSSDLYLGISFNTTTREIMEFIPIWIA--NRDTPVTS---NASLLLTSKGELQIIDRGSIIWSGAPSSSNS
...|..   .......    |.||....     ...||...  . .  .  ..| |  ||| ||..   .. | ..| |.| | | ....||   . .|.
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ----WCNGIWYKNISNK--QRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD-NRPVWSSNTT-RNN

GITQAVLLDSGNFVLTDNAFDPRDDNATYPWQSFDHP
| . |||.|.||||. |..    .|   . |||||||
GNYVAVLQDDGNFVIYDPD---DNDSGNFIWQSFDHP
S_locus_glycop IRAKg_k-2.AA S_locus_glycop 219-325 27 1.2e-18 66.36 Pfam 1-117 (117) Show / Hide 
Range on Protein: 219-325
Range on HMM: 1-117/117
Sequence Identity: 27% (32 aa)

WTSGAWNGKIFSLVPQMTDN-----YLYTFI----FNATNPPSFTWFE-KSFQHSIFRLGHDGRIEVKQ-LDGNGNWYTPWAVPANICDVTSLCGSNSVC
| || ||| .|| .|.| .      |.| |.    .|.    ..|..  ... .| |.. ..| ...    . . .| . | .|.. ||.  .||....|
WRSGPWNGIRFSGIPWMEMQYPWSYYVYNFTLQQDDNNEE-VYYTYHMTNNSIYSRFTMSSEGYLQRFTWNPNSQDWNLFWYAPKDQCDYYRRCGPYGYC

SSSLNPPCSCPTGSSPSN
 .. .|.|.|  |  | |
DMNTSPMCNCIKGFVPKN
SKG6 IRAKg_k-2.AA SKG6 347-382 30 0.000196 18.88 Pfam 1-40 (40) Show / Hide 
Range on Protein: 347-382
Range on HMM: 1-40/40
Sequence Identity: 30% (12 aa)

RSSSKNS--GVAIGVGAGI-VLLLLAGLAAFVI-ARRRRK
 ...|..  .|||..| .| |  ....| .|.. ..||.|
KPTDKHWKTTVAIACGVVIPVGVIILVLICFLFCWWRRKK
Kinase IRAKg_k-2.AA TKL 427-656 18 2.4e-51 176.91 In-house 1-364 (364) Show / Hide 
Range on Protein: 427-656
Range on HMM: 1-364/364
Sequence Identity: 18% (71 aa)

LGSGGFGEVFKGSIQG----------QAVAVKRLIK---------------------------------------------L------------------
.||||||||.||  .|          . ||||.. .                                             |                  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------QRLLVYEFVERGS-LDRTLFNRDAENSVVLSWSQRFGIALGTAKGLAYLHE----DCRHR--IIHCDIKPENILLDAEMK---------
           |  .|.|....|| |.. .            |.||. .||..|.|..|||      |.    |||.|.|..|||.|  ..         
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNP

-----PKIADFGLAKLLGREFS------------------RVVTSMRGTRGYLAPEWLSNM----------------PITPKADVYSYGMTLLEIISGRR
     .||.||||.. . ....                      . .|| ...||| | ..                . ..|.||||.|. | ||....|
NADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR

NIDFR-NDQIFFYPL----WAAEQVCNGEFAKLPDDRLDE-----WDEEELRRAARTAIWCVQDEEINRPSMKTVVQML
   .. .. .  ..     . ...||.     .....  .     . .  ... .. . .| . .  .|||...... |
--PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKg_k-2.AA IRAK 457-590 39 1.6e-34 119.85 In-house 80-225 (317) Show / Hide 
Range on Protein: 457-590
Range on HMM: 80-225/317
Sequence Identity: 39% (57 aa)

LVYEFVERGSLDRTLFNRDAENS-VVLSWSQRFGIALGTAKGLAYLHEDC-RHRIIHCDIKPENILLDAEMKPKIADFGLAKLL----GREFSRV----V
|||..   |||   |  .|. ..   ||| ||. |..|||.|. .||..     ||| |||. |||||. . |||.||||.       ..| . .    .
LVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMT

TSMRGTRGYLAPEWLS--NMPITPKADVYSYGMTLLEIISGRRNID
   |||  |..|| .      .|.| |||| |  |||...|.|  .
SHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVLTGCRAVY
Kinase IRAKg_k-2.AA Pkinase 457-586 31 2.5e-33 118.92 Pfam 77-209 (293) Show / Hide 
Range on Protein: 457-586
Range on HMM: 77-209/293
Sequence Identity: 31% (45 aa)

LVYEFVERG----SLD----RTLFNRDAENSVVL--SWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKP----KIADFGLAKLLGREF
.| |..| |    .|     .       ... ..  |. .   ... ...||.|.|.    .|||.|.||||||.| .. .    ||.||||||..    
MVMEYCEGGLYVMDLFDYIST-------WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-N

SRVVTSMRGTRGYLAPEWLS-NMPITPKADVYSYGMTLLEIISGR
..  |.  ||..|.|||..  . ...||.|..|.| .| | ..||
NS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase IRAKg_k-2.AA MLK 456-586 28 1.9e-28 95.84 In-house 86-233 (291) Show / Hide 
Range on Protein: 456-586
Range on HMM: 86-233/291
Sequence Identity: 28% (43 aa)

LLVYEFVERGSLDRTLFNRDAENS---------VVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDA------EMKPKIADFGLAKLLGR
..| |..| ||| . | ... . .         .| . .. . .||  |.|..|||.. .. ||| |.|. |||.|.      ... ||.|||..    |
CIVMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS----R

EFSRV---VTSMRGTRGYLAPEWL---SNMPITPKADVYSYGMTLLEIISGR
....     .|..||  . ||| .    . . . |.||.|.|. | |.....
DWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKg_k-2.AA TKL-Unique 454-585 30 3.2e-27 93.14 In-house 74-224 (290) Show / Hide 
Range on Protein: 454-585
Range on HMM: 74-224/290
Sequence Identity: 30% (46 aa)

QRLLVYEFVERGSLDRTLF-----NRDAENSVVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAE-----MKPKIADFGLAKLLGREFS
.. .| |....|||.  |      |   .|.  |...||  .|.  |.|. |||      |||.|.|. |.|.| .     .. ||.||||.|.. ..  
NMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINK

RVVT--------SMRGTRGYLAPEWLSN--MPITPKADVYSYGMTLLEIISG
  ..        .  |.  ..||| |..    .. |.||||.|. | ||...
MTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKg_k-2.AA Dicty4 460-582 31 1.2e-25 82.71 In-house 82-210 (277) Show / Hide 
Range on Protein: 460-582
Range on HMM: 82-210/277
Sequence Identity: 31% (41 aa)

EFVERGSLDRTLFN--RDAENSVVLSWSQRFG---IALGTAKGLAYLHE-DCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLLGREFSRVV--TSMRG
|.. .|.| . | .   .   |. |.|. .     .|. .|.|...||. ..  .||| |.|. |.| |. .. |..||||...  .. .     ... |
EYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACG

TRGYLAPEWLSNMPITPKADVYSYGMTLLEI
| .. ||| . . | . ||||||.|. | ||
TPCWMAPEVMMHQPYNEKADVYSFGIVLWEI
Kinase IRAKg_k-2.AA RIPK 457-586 32 2.1e-23 76.57 In-house 79-225 (290) Show / Hide 
Range on Protein: 457-586
Range on HMM: 79-225/290
Sequence Identity: 32% (48 aa)

LVYEFVERGSLDRTLFNRDAENSVVLSWSQRFGIALGTAKGLAYLHEDCRH-RIIHCDIKPENILLDAEMKPKIADFGLAKLLGRE--FS--------RV
.| |. | |||  .|  .       . |. |. .   .. |  |||  .    ||| | ||||||.|...  ||||||||. ..    ..        . 
IVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYS

VTSMR--GTRGYLAPEWLS---NMPI---TPKADVYSYGMTLLEIISGR
 .|    ||  |..|| .      ||   ||| ||||..... |. ...
MKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQK
Kinase IRAKg_k-2.AA DRK 456-583 35 4.1e-22 71.72 In-house 73-196 (258) Show / Hide 
Range on Protein: 456-583
Range on HMM: 73-196/258
Sequence Identity: 35% (47 aa)

LLVYEFVERGSLDRTLFNRDAENSVVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAK----LLGREFSRVVTSMRG
. . |.  |||| . | .     |. ..|. .  ...  |||. |||  |   ||| | |  | | |   . |.|||||.      . . | .    | |
CICMEYMPRGSLYNILHD----ESIEMDWPLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAM---TMCG

TRGYLAPEWLSNMPITPKADVYSYGMTLLEII
| .  ||| | | . | ||||||..  | |..
TPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAKg_k-2.AA LRRK 457-587 31 8.4e-22 73.9 In-house 132-281 (351) Show / Hide 
Range on Protein: 457-587
Range on HMM: 132-281/351
Sequence Identity: 31% (49 aa)

LVYEFVERGSLDRTLFNRDAENSV-----VLSWSQRFGIALGTAKGLAYLHEDCRHR--IIHCDIKPENILL---D---------AEMKPKIADFGLAK-
.| |..  |.|.. |.|. ....      ..||. .  |||  |||..|||   .|.  |||.| |..||||   .         |... ||||||.   
MVMEYAPHGDLYHFLHNK-KQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRM

--LLGRE-FSRVVTSMRGTRGYLAPEWLSNM---PITPKADVYSYGMTLLEIISGR-R
   .. . ....|    |. |..||| . ..     | |.|.||.|| | |..... .
FQCFHMGVAKGCV----GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase IRAKg_k-2.AA STE 490-586 29 1.5e-21 72.97 In-house 156-265 (359) Show / Hide 
Range on Protein: 490-586
Range on HMM: 156-265/359
Sequence Identity: 29% (35 aa)

IALGTAKG-LAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLLGR---------------EFSRVVTSMRGTRGYLAPEWLSNM------PIT
|.  . || |.|||.     ||| |||| ||||      |..|||... |                   .   ... ||  . ||| ....      . .
ICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYD

PKADVYSYGMTLLEIISGR
 |.|..| | |..| . |.
TKCDIWSLGCTIIEMATGK
Kinase IRAKg_k-2.AA HH498 456-586 25 2.1e-21 64.26 In-house 79-223 (284) Show / Hide 
Range on Protein: 456-586
Range on HMM: 79-223/284
Sequence Identity: 25% (37 aa)

LLVYEFVERGSLDRTL-------------FNRDAENSVVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLLGREF
..| .... ||| . |              . . .|  ...   .  |..  |.|  |||.   | ||| |    |||.... . ..||||    .    
AIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMH

SRVVTSMRGTRGYLAPEWLS-NMPITPKADVYSYGMTLLEIISGR
    |.  |   . |||  | .   . |.||.||.| . |. ...
DDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTRE
S_TKc IRAKg_k-2.AA S_TKc 421-631 22 1.2e-14 37.71 SMART 1-231 (231) Show / Hide 
Range on Protein: 421-631
Range on HMM: 1-231/231
Sequence Identity: 22% (58 aa)

DGFKKRLGSGGFGEVFKGSIQG--QAVAVKRLIKLQRL---------------------------LVYEFVER--GSLDRTLFNRDAENS-VVLSWSQRF
  . . .|.|.||.|.|.   .  . ||.|..   ...                           .| |...   |.| . . .|  .   ....  .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

GIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLLGREFSRVVTSMRGTRGYLAPEWLSNMPITP-KADVYSYGMTLLEIISGRR
 ..  ....|.|.|.   |.|||.|.||||||||     ||.|||||..|        |.. ||. |.||| |   . .. |.|..| | .| | ..|. 
FYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYP

---NIDFRNDQIFFYPLWAAEQVCNGEFAKLPDDRLDEWDEEE-------LRRA
   ...   ..|   .  | .   .. . | |..|.   .  .           
PFPQMQMMFKKIG--SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc IRAKg_k-2.AA TyrKc 421-656 21 1.8e-13 -4.81 SMART 1-280 (280) Show / Hide 
Range on Protein: 421-656
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

DGFKKRLGSGGFGEVFKGSIQGQAVAVKRLI---------------KL-------------------------QRLLVYEFVERGSLDRTL-FNRDAENS
  ..| ||.| ||||.||    . |||| |                ||                         . ..| |... |.|.  |  .|.    
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

VVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLLGRE----FSRVVTSMR---GTRG-----YLAPEWLSNMPIT
  |....   ...  |.| .|||.    ..|| |.   |.|....   ||.||||.. .. .     |  . ...   |...      .||| .     |
--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKADVYSYGMTLLEIISGRRNIDFRNDQIF--FYPLWAAEQVCNGEFAKLPDDRLDEW----DEEELRRAARTAIWCVQDEEINRPSMKTVVQML
.| ||.|.| .. || .  .      ..|.    .  . |.| .|.  . |.. . .       .|.    .   .| . .  .||....... .
TKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-PMSFVCCPDEM---YQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAKg_k-2.AA Pkinase_Tyr 454-584 27 9.3e-10 33.67 Pfam 81-209 (270) Show / Hide 
Range on Protein: 454-584
Range on HMM: 81-209/270
Sequence Identity: 27% (37 aa)

QRLLVYEFVERGSLDRTLFNRDAENSVVLSWSQRFGIALGTAKGLAYLHEDCRHRIIHCDIKPENILLDAEMKPKIADFGLAKLL-GREFS-RVVTSMRG
| ..| |... |.|.  | ..  |.   |. ..  ....  |||..||..   ...|| |.   |.|.. ... ||.|||||...   .   |. .. . 
QIYIVMEYMPHGDLLDYLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLES---KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKL

TRGYLAPEWLSNMPITPKADVYSYGMTLLEIIS
    .||| ....  | | ||.|.| .. ||..
PIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKg_k-2.AA IRAK 423-452 41 8.5e-09 27.47 In-house 1-34 (317) Show / Hide 
Range on Protein: 423-452
Range on HMM: 1-34/317
Sequence Identity: 41% (14 aa)

FKK--RLGSGGFGEVFKGSIQGQA--VAVKRLIK
| |  |.|.||||.|..| .....  .|||.|..
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKE
Kinase IRAKg_k-2.AA Dicty4 423-448 53 1.3e-08 25.0 In-house 3-28 (277) Show / Hide 
Range on Protein: 423-448
Range on HMM: 3-28/277
Sequence Identity: 53% (14 aa)

FKKRLGSGGFGEVFKGSIQGQAVAVK
. .|.|.|.||||.||.  |..||||
IEQRIGKGSFGEVYKGTWRGKEVAVK
Kinase IRAKg_k-2.AA MLK 423-449 43 4e-07 20.92 In-house 3-34 (291) Show / Hide 
Range on Protein: 423-449
Range on HMM: 3-34/291
Sequence Identity: 43% (14 aa)

FKKRLGSGGFGEVFKGSIQGQA-----VAVKR
|.. .|||.||.|.||  ...      |||||
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKR
Kinase IRAKg_k-2.AA HH498 423-449 51 6e-07 17.64 In-house 3-29 (284) Show / Hide 
Range on Protein: 423-449
Range on HMM: 3-29/284
Sequence Identity: 51% (14 aa)

FKKRLGSGGFGEVFKGSIQGQAVAVKR
|..  ||| ||.|.||   .  |||||
FHEKIGSGSFGKVYKGEWRNKIVAVKR
Kinase IRAKg_k-2.AA DRK 424-450 51 9e-06 15.53 In-house 4-30 (258) Show / Hide 
Range on Protein: 424-450
Range on HMM: 4-30/258
Sequence Identity: 51% (14 aa)

KKRLGSGGFGEVFKGSIQGQAVAVKRL
  | | |..|||| |.  |  ||||.|
GNRIGRGNYGEVFRGTWRGTQVAVKML
Kinase IRAKg_k-2.AA LRRK 422-450 36 1.7e-05 15.43 In-house 2-31 (351) Show / Hide 
Range on Protein: 422-450
Range on HMM: 2-31/351
Sequence Identity: 36% (11 aa)

GFKKRLGSGGFG-EVFKGSIQGQAVAVKRL
 . . .|.|||| .|...  .|| |.|.|.
KIEEQIGRGGFGTFVYRAKWRGQPVHVCRM
Kinase IRAKg_k-2.AA TKL-Unique 423-450 42 8.1e-05 13.12 In-house 1-28 (290) Show / Hide 
Range on Protein: 423-450
Range on HMM: 1-28/290
Sequence Identity: 42% (12 aa)

FKKRLGSGGFGEVFKGSIQGQAVAVKRL
| . .|.||.|.|.||   |  ||.|..
FWNKIGEGGYGQVYKGKWRGYPVAIKQF
Kinase IRAKg_k-2.AA RIPK 427-437 81 0.000745 8.98 In-house 1-11 (290) Show / Hide 
Range on Protein: 427-437
Range on HMM: 1-11/290
Sequence Identity: 81% (9 aa)

LGSGGFGEVFK
.|.||||||||
VGGGGFGEVFK
Kinase IRAKg_k-2.AA Pkinase_Tyr 423-450 47 0.001165 13.02 Pfam 3-36 (270) Show / Hide 
Range on Protein: 423-450
Range on HMM: 3-36/270
Sequence Identity: 47% (16 aa)

FKKRLGSGGFGEVFKGSIQ------GQAVAVKRL
| | ||.| ||||.||         .. |||| |
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML
Kinase IRAKg_k-2.AA STE 423-450 19 0.002929 7.51 In-house 1-47 (359) Show / Hide 
Range on Protein: 423-450
Range on HMM: 1-47/359
Sequence Identity: 19% (9 aa)

FKK--RLGSGGFGEVFKG-----------------SIQGQAVAVKRL
...  ..|.|.||.|.|.                  ..|. .|.|..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQM
Kinase IRAKg_k-2.AA MLK 645-656 50 0.055643 2.82 In-house 280-291 (291) Show / Hide 
Range on Protein: 645-656
Range on HMM: 280-291/291
Sequence Identity: 50% (6 aa)

NRPSMKTVVQML
.|||.. .|| |
KRPSFRQIVQHL
Kinase IRAKg_k-2.AA Pkinase 423-452 40 0.066611 7.81 Pfam 3-34 (293) Show / Hide 
Range on Protein: 423-452
Range on HMM: 3-34/293
Sequence Identity: 40% (13 aa)

FKKRLGSGGFGEVFKGSIQGQA--VAVKRLIK
.....|||.||.|.|.  .|    ||||.. |
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKK
Kinase IRAKg_k-2.AA DRK 646-658 46 0.103885 1.61 In-house 246-258 (258) Show / Hide 
Range on Protein: 646-658
Range on HMM: 246-258/258
Sequence Identity: 46% (6 aa)

RPSMKTVVQMLEG
||||  ... || 
RPSMQECLERLEA
Kinase IRAKg_k-2.AA Dicty4 644-658 35 0.160348 1.04 In-house 261-277 (277) Show / Hide 
Range on Protein: 644-658
Range on HMM: 261-277/277
Sequence Identity: 35% (6 aa)

INRPSMKTVVQM--LEG
..|||.. ..|   || 
QHRPSFEEIIQRRILEH