Gene IRAKm_k-2 (S.moellendorffii)

IRAKm_k-2

Species: S.moellendorffii
Alias: IRAKm_k-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_k-2.AA Protein None 533 None Fasta, JSON
IRAKm_k-2.NA RNA None 1602 None Fasta, JSON
IRAKm_k-2.kin_dom Protein Kinase Domain None 190 None Fasta, JSON

Protein domain

Protein domains of IRAKm_k-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PAN_AP IRAKm_k-2.AA PAN_AP 56-132 19 3.6e-07 31.05 SMART 1-85 (85) Show / Hide 
Range on Protein: 56-132
Range on HMM: 1-85/85
Sequence Identity: 19% (17 aa)

AENHHFLNVSGAGYFSNNYT----KADRVSTLSECWSLCLANCSCSALFYNKQSSTCFFVD--RMYGGLT------RDPNFDGFLKLQN
 . ..|. .... .  .. .    .   | .| ||...|| |||| .  |.. ...| . .  .. |. .        ||.  ..  .|
CCDDCFVRMPNMKL--FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase IRAKm_k-2.AA TKL 208-485 20 2e-68 233.63 In-house 1-364 (364) Show / Hide 
Range on Protein: 208-485
Range on HMM: 1-364/364
Sequence Identity: 20% (82 aa)

LGKGGFGTVYEGTLAD---------GRKVAVKRLENRN----------------------------QNDRGFLAEMASLGRISHHNVVQLYGFCSEKNQ-
.|.||||.|| |..           |. ||||..  .|                            ..   .  |. .. |..| |.||..|.| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LMLVYEYVVNGSLDKWLFEERFLNWQSRRDIALGLAQGLAYLHEESR-----QLIIHLDIKPENVLLDDKFR--------------PK
            |..|.||. .|||   |       |. | ..||. |.|..||| .         ||| |.|..|.|.|....              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

LSDFGMAKLLKTR-----------------DVSQTVTDVRGTPGYLAPEWLLHS----------------VATKKCDVYSYGMVLLELIGGRRNLSKLGG
..||| .. ....                 . ..|   ..|||...||| |  .                 ...||||||.|.|| |.. ..|       
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-------

HGGEDCREAPMDEEEQALWWYFPAWVVARVSKREFLKVVDTSIRDSVD------------EDEVKSMLQVALWCIQDNPSQRPPMDTVVQML
              .. .. . . .     .. .| .|.| . |  ..            .|  .|| . . .| . .|..|| ...... |
-------------PYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase IRAKm_k-2.AA Pkinase 202-397 28 4.2e-58 204.15 Pfam 1-209 (293) Show / Hide 
Range on Protein: 202-397
Range on HMM: 1-209/293
Sequence Identity: 28% (62 aa)

GNFASSLGKGGFGTVYEGTLADGRK-VAVKRLENRNQNDRGF-----LAEMASLGRISHHNVVQLYGFCSEKNQLMLVYEYVVNG----SLDKWLF--EE
  . . .|.|.||.||...  . .| ||||... |....        |.| . . |..| |.|.||... .|. . .| ||. .|    .|  ..   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RFL--NWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRP----KLSDFGMAKLLKTRDVSQTVTDVRGTPGYLAPEWLL-HSVATKKCD
. .   ..  ..... ...||.|.|..    ||| |.||||.|.|..  .    |..||| ||...    ..  |.. |||.|.|||... ..  ..|.|
GCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGMVLLELIGGR
..|.| .| |.. ||
MWSCGCILYEMLCGR
Kinase IRAKm_k-2.AA IRAK 204-398 36 4.3e-48 166.08 In-house 1-222 (317) Show / Hide 
Range on Protein: 204-398
Range on HMM: 1-222/317
Sequence Identity: 36% (82 aa)

FASS--LGKGGFGTVYEGTLADGR-KVAVKRLENR-----NQNDRGFLA---EMASLGRISHHNVVQLYGFCSEKNQLMLVYEYVVNGSLDKWLFEERF-
|. .  .|.||||.|| | .      .|||.| .      |. .. |..   |. .. |. | |.| |||.|.|  .. |||.|  ||||   |      
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

-----LNWQSRRDIALGLAQGLAYLHEES-RQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLL--KTRDVSQTV-----TDVRGTPGYLAPEWLL--HSV
     | |. | .|..|.| |. .||. .    ||| |||. |.|||. | ||..|||..     .    .||.       ||||  |..|| .      
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATKKCDVYSYGMVLLELIGGRR
 ||| |||| | ||||.. |.|
LTKKTDVYSFGIVLLEVLTGCR
Kinase IRAKm_k-2.AA TKL-Unique 204-394 29 3.7e-40 139.32 In-house 1-222 (290) Show / Hide 
Range on Protein: 204-394
Range on HMM: 1-222/290
Sequence Identity: 29% (65 aa)

FASSLGKGGFGTVYEGTLADGRKVAVKRLEN----RNQNDRGFLAEMASLGRIS-HHNVVQLYGFCS----EKNQLMLVYEYVVNGSLDKWLF-------
| ...| ||.|.|| |. . | .||.|....    .|.  . |  |   . ..  | |.|...|.|       ... .| ||.  |||.. |        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

---EERFLNWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDK-----FRPKLSDFGMAKLLKTRDVSQTV-------TDVRGTPGYLAPEWL
   ..  ||.| | ..|.  |||. ||| ..   |||.|.|. |.|.| .     .. |..||| .|...... . .        ... |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LH--SVATKKCDVYSYGMVLLELI
    .  ..|.||||.|.|| |..
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase IRAKm_k-2.AA MLK 202-394 27 5.8e-40 136.34 In-house 1-230 (291) Show / Hide 
Range on Protein: 202-394
Range on HMM: 1-230/291
Sequence Identity: 27% (63 aa)

GNFASSLGKGGFGTVYEGTLADGRK-----VAVKRLE-------NRNQNDRGFLAEMASLGRISHHN----VVQLYGFCSEKNQ-LMLVYEYVVNGSLDK
 .|   .|.|.|| |. |.   ..      ||||| .            .. |  |   | ..|| |    ..|.|| |.. .. . .| ||. .|||  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFEER--------------FLNWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDD------KFRPKLSDFGMAKLLKTRDVSQTVTDVRGTP
 | ..|                  ..  ..||  |.|..|||.. ...||| |.|. |.|.|.      .   | .||| .. .....  .. .. .||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYLAPEWL---LHSVATKKCDVYSYGMVLLELI
 . ||| .    ..  ..||||.|.|.|| |..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
S_TKc IRAKm_k-2.AA S_TKc 202-492 23 1.5e-39 138.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 202-492
Range on HMM: 1-231/231
Sequence Identity: 23% (71 aa)

GNFASSLGKGGFGTVYEGTLAD-GRKVAVKRLENRNQNDRGFLAEMASLGRISHHNVVQLYGFCSEKNQLMLVYEYVVN--GSLDKWLFEERF------L
  .   .|||.||.|| ..  . ||.||.|..       . .. |.. | .  | |.|.||... . . | .| ||. .  |.| . . . .       .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

NWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLLKTRDVSQTVTDVRGTPGYLAPEWLLHSVATK-KCDVYSYGMVLL
.    | ..  ....|.|.|.   . ||| |.||||.|||.  . |..|||.|..|         | . ||| |.||| |     .| |||..| | .| 
PE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELIGGRR---NLSKLGGHGGEDCREAPMDEEEQALWWYFPAWVVARVSKREFLKVVDTSIRDSVDEDEVKSMLQVALWCIQDNPSQRPPMDTVVQ--MLE
|.. |.    .. ..  . |                                                 .....    | | .|..||    . |  .. 
EMLCGYPPFPQMQMMFKKIG------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

GRKEIL
   . .
KCHPWF
Kinase IRAKm_k-2.AA LISK 207-398 29 1.7e-38 122.58 In-house 1-237 (296) Show / Hide 
Range on Protein: 207-398
Range on HMM: 1-237/296
Sequence Identity: 29% (71 aa)

SLGKGGFGTVYEGTLA-DGRKVAVKRLE------NRNQNDRGFLAEMASLGRISHHNVVQLYGFCSE-KNQLMLVYEYVVNGSLDKWLFEERF----LNW
..|||.|| || ||.  .|. .|.| ..      |.. . . .| |.. . ...| |.|| .| | . . ||..| ||.  | |   |. . .    | |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

QSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDK----FRPKLSDFGMAKLLKTRDVS---------------------QTVTDV-----R---
. | .|||. |.|..|||.   . ||| | |  |.|....    .| |. ||| |...  .. |                      .  .      .   
PQRVKIALDIACGMSYLHS---MNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

---GTPGYLAPEWLLHSVATKKCDVYSYGMVLLELIGGRR
   |||   ||| || .  . .|||.|.|.||.|.|....
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
Kinase IRAKm_k-2.AA Dicty4 203-393 33 2.9e-37 121.96 In-house 2-210 (277) Show / Hide 
Range on Protein: 203-393
Range on HMM: 2-210/277
Sequence Identity: 33% (70 aa)

NFASSLGKGGFGTVYEGTLADGRKVAVKRLENRNQND-----RGFLAEMASLGRISHHNVVQLYGFCS----EKNQLMLVYEYVVNGSLDKWLFE-----
|. . .|||.||.|| ||   | .|||| | |.|||.       |..| . .. |.| |.....| |     ..  .. | ||.  |.| . |       
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

--ERFLNWQSRRD---IALGLAQGLAYLHE-ESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLLKTRDVSQT-VTDVRGTPGYLAPEWLLHSVATKKC
  .  | |  ..    .|.  |.|...||.  ..  |||.|.|. | | |. .| | .||| ... |.    ..  . . |||.. ||| . |   . | 
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGMVLLEL
||||.|.|| |.
DVYSFGIVLWEI
Kinase IRAKm_k-2.AA CAMK 207-390 17 8.4e-37 115.61 In-house 1-324 (425) Show / Hide 
Range on Protein: 207-390
Range on HMM: 1-324/425
Sequence Identity: 17% (56 aa)

SLGKGGFGTVYEGTLA-DG------------RKVAVKRLENR-----------------------------NQNDRGFLAEMASLGR-------ISHHNV
 ||.|.||.|....   ..            .|||.| .. .                              .. . .. |.. . .       ..| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYG--------------------FCSEKNQLMLVY---EYVVNG----SLDKWLFEE---------------RFLNWQSRRDIALGLAQGLAYLHEES
..||                     | . .... .|    ||. .|     |  .. |                . .. .  | .   ......|.|.  
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHS--

RQLIIHLDIKPENVLLDDK-----------------FRPKLSDFGMAKLLKTRDV---------------------SQTVTDVRGTPGYLA-PEWLLH--
 . |.|.|.||||.||||.                 .  |..|||.|. ..  .                       |  ... |||.| | ||.|.   
-HNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

------------SVATKKCDVYSYGMVL
               ..|||. | | .|
HCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase IRAKm_k-2.AA TK 202-393 15 1.8e-35 115.85 In-house 1-387 (486) Show / Hide 
Range on Protein: 202-393
Range on HMM: 1-387/486
Sequence Identity: 15% (61 aa)

GNFASSLGKGGFG---TVYEGTLADGR--------------------------KVAVKRLENR-NQNDRGFLA--------------EMASLGRIS----
  .   ||.| ||   .||.|.. ...                          .|||| |    ..... |..              |.. .   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HHNVVQLYGFCSEK------------NQLMLVYEYVVNGS----LDKWLFEER----------------------------------------------
 | |.|.||| |...              .|.| ||. .|.    |...| . |                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------FLNWQSRRDIALGLAQGLAYLHEE----SRQLIIHLDIKPENVLLDDKFR-----------PKLSDFGMA
                              .|. . .  ... .|.|..|||.       | ..| |.   |.|.... .            |..|||..
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

KLL---KTRDVSQ----TVTDVRGTPG-------------------------YLAPEWLLHSV---------ATKKCDVYSYGMVLLEL
.      .||. .    .... .||..                         ..||| |.. |          | | ||.|.| .. |.
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase IRAKm_k-2.AA Dicty4-Unclassified 203-396 32 1.9e-34 115.37 In-house 2-204 (263) Show / Hide 
Range on Protein: 203-396
Range on HMM: 2-204/263
Sequence Identity: 32% (69 aa)

NFASSLGKGGFGTVYEGTLADGRKVAVKRLENRNQNDR-----GFLAEMASLGRISHHNVVQLYGFC----SEKNQLMLVYEYVVNGSLDKWLF-----E
     .||| |  |. |    |. |||| .       |      |..| . || |.| | |..|| |    | |  .. | |    | |           
QIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

ERFLNWQS--RRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLLKTRDVSQTVTDVRGTPGYLAPEWLLHSVATKKCDVYSY
.. .   .     .|.  |||...||  .|  .|| |||  |.|.|  |  |  |||..      |  .. | . |||   .|| | |   . | |||||
QQPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSY

GMVLLELIGG
.|.| ||. |
AMMLYELATG
Kinase IRAKm_k-2.AA DRK 209-394 34 3.3e-32 106.39 In-house 8-196 (258) Show / Hide 
Range on Protein: 209-394
Range on HMM: 8-196/258
Sequence Identity: 34% (67 aa)

GKGGFGTVYEGTLADGRKVAVKRLENRNQNDRGFLAEMAS----LGRISHHNVVQLYGFCSEKNQLMLVYEYVVNGSLDKWLFEERF-LNWQSRRDIALG
|.|..| |. ||   | .||||.| | | ||  || |..     . .  | |..|  | | .      . ||   ||| . | .|   . |  .  ... 
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFD

LAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAK-LLKTRDVSQTVTDVRGTPGYLAPEWLLHSVATKKCDVYSYGMVLLELI
 | |. |||  .   ||| | |  | | |. .. | .||| .    | ..   . | . |||.  ||| |     | | ||||.. || |..
CAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAKm_k-2.AA Pkinase_Tyr 208-394 26 2.1e-29 100.2 Pfam 7-208 (270) Show / Hide 
Range on Protein: 208-394
Range on HMM: 7-208/270
Sequence Identity: 26% (55 aa)

LGKGGFGTVYEGTLA-----DGRKVAVKRL--ENRNQN--DRGFLAEMASLGRI-SHHNVVQLYGFCS-EKNQ--LMLVYEYVVNGSLDKWLFE----ER
||.| ||.||.||.      .. .|||| |      ..   . |..|.. .  . .|.|.|.||| |. .. .  ...| ||. .|.|.. | .    ..
LGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQ

FLNWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLLKTRDVSQ-TVTD-----VRGTPGYLAPEWLLHSVATKKCDVY
 |. .   ....  |.|..||..     .|| |.   |.|.....  | .|||.|... . |    ....     .. .    ||| . ... | | ||.
PLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWM----APECINYGKFTTKSDVW

SYGMVLLELI
|.| .. |..
SFGVLMWEIF
Kinase IRAKm_k-2.AA TyrKc 202-485 22 1.2e-23 85.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 202-485
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

GNFASSLGKGGFGTVYEGTLADGRKVAVKRLENRNQNDRGFLAEMASLGRI--SHHNVVQLYGFCSEK-------NQLMLVYEYVVNGSLDKWL-FEERF
  .   || | ||.||.||.   ..|||| | .     . |. |.  . ..  .| |.|.||| |...        .||.| ||. .|.|.. |   .. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

LNWQSRRDIALGLAQGLAYLHEESRQLIIHLDIKPENVLLDDKFRPKLSDFGMAKLLKTRD---VSQTVTDVR---GTPG-----YLAPEWLLHSVATKK
|...   ....  |.| .|||.     .|| |.   |.|...... | ||||... ..  |   .|. . ...   |. .      .||| . ... | |
LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTK

CDVYSYGMVLLELIGGRRNLSKLGGHGGEDCREAPMDEEEQALWWYFPAWVVARVSKREFLKVVDTSIRDSVDED--------EVKSMLQVALWCIQDNP
 ||.|.| .. |.                .. . . ....|             .| .| .. |..  |    ..          . | |. ..| . .|
SDVWSFGVCMWEIF--------------TYGQQPYPGMIQQ------------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDP

SQRPPMDTVVQML
..|| . .... .
EDRPTFSEIHECF
Kinase IRAKm_k-2.AA DRK 467-487 33 4.7e-05 13.11 In-house 238-258 (258) Show / Hide 
Range on Protein: 467-487
Range on HMM: 238-258/258
Sequence Identity: 33% (7 aa)

CIQDNPSQRPPMDTVVQMLEG
|   .|..|| |. ... || 
CWNEDPQHRPSMQECLERLEA
Kinase IRAKm_k-2.AA TK 462-485 20 9e-05 11.08 In-house 463-486 (486) Show / Hide 
Range on Protein: 462-485
Range on HMM: 463-486/486
Sequence Identity: 20% (5 aa)

QVALWCIQDNPSQRPPMDTVVQML
.. . | . .|..|| .......|
DLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAKm_k-2.AA IRAK 451-485 28 0.000205 11.75 In-house 283-317 (317) Show / Hide 
Range on Protein: 451-485
Range on HMM: 283-317/317
Sequence Identity: 28% (10 aa)

SVDEDEVKSMLQVALWCIQDNPSQRPPMDTVVQML
.......|.|.|.|. |       |..|. |.| |
PCPPNMEKEMCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAKm_k-2.AA Dicty4-Unclassified 466-485 40 0.000576 9.43 In-house 244-263 (263) Show / Hide 
Range on Protein: 466-485
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCIQDNPSQRPPMDTVVQML
||  . |  || |. ..| |
WCWHNDPNKRPTMNQIIQYL
Kinase IRAKm_k-2.AA LISK 461-485 32 0.000821 8.04 In-house 272-296 (296) Show / Hide 
Range on Protein: 461-485
Range on HMM: 272-296/296
Sequence Identity: 32% (8 aa)

LQVALWCIQDNPSQRPPMDTVVQML
|.....|.  .|. ||  ...|| |
LDLCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAKm_k-2.AA MLK 467-485 36 0.003485 7.05 In-house 273-291 (291) Show / Hide 
Range on Protein: 467-485
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CIQDNPSQRPPMDTVVQML
| ...|..|| .. .|| |
CWNQDPHKRPSFRQIVQHL
Kinase IRAKm_k-2.AA Dicty4 466-487 33 0.017316 4.31 In-house 254-277 (277) Show / Hide 
Range on Protein: 466-487
Range on HMM: 254-277/277
Sequence Identity: 33% (8 aa)

WCIQDNPSQRPPMDTVVQM--LEG
||   .|..|| .  ..|   || 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKm_k-2.AA TKL-Unique 467-485 42 0.018191 4.73 In-house 272-290 (290) Show / Hide 
Range on Protein: 467-485
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CIQDNPSQRPPMDTVVQML
|  ..|||||  |...  |
CWHHDPSQRPSFDEIIHRL
Kinase IRAKm_k-2.AA Pkinase_Tyr 465-485 23 0.247102 5.14 Pfam 250-270 (270) Show / Hide 
Range on Protein: 465-485
Range on HMM: 250-270/270
Sequence Identity: 23% (5 aa)

LWCIQDNPSQRPPMDTVVQML
. | . .|..|| .  ....|
KQCWHYDPEDRPTFSEIHEQL