Gene LLEC_g (S.moellendorffii)

LLEC_g

Species: S.moellendorffii
Alias: LLEC_g
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LLEC

Sequence

Name Sequence Type Origin Length Description Download
LLEC_g.AA Protein None 82 None Fasta, JSON
LLEC_g.NA RNA None 249 None Fasta, JSON
LLEC_g.kin_dom Protein Kinase Domain None 76 None Fasta, JSON

Protein domain

Protein domains of LLEC_g.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LLEC_g.AA Pkinase_Tyr 3-74 29 1.4e-15 53.43 Pfam 12-96 (270) Show / Hide 
Range on Protein: 3-74
Range on HMM: 12-96/270
Sequence Identity: 29% (25 aa)

FGGVYEGVLP-----DGRKVAVKQL--ESTGQG--KKEFYAEVSILGTI-HHWNLVKLLGFCS-EGLN--KLLVYEHMENSSLDK
|| ||.|..      .. .|||| |   .. .   ...| .|..|. .. || |.|.|.| |. .|     ..| |.|.. .|..
FGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLD
Kinase LLEC_g.AA IRAK 1-72 34 1.2e-10 34.09 In-house 10-90 (317) Show / Hide 
Range on Protein: 1-72
Range on HMM: 10-90/317
Sequence Identity: 34% (28 aa)

GGFGGVYEGVLPDGRK--VAVKQLE-----STGQGKKEFYA---EVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHMENSSL
|||| || |.. ..    .||| |      |... ...| .   |. .. ...| |.| |.|.|.|. .  |||. | | ||
GGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSL
Pkinase LLEC_g.AA Pkinase 1-76 24 2e-10 37.97 Pfam 10-95 (293) Show / Hide 
Range on Protein: 1-76
Range on HMM: 10-95/293
Sequence Identity: 24% (21 aa)

GGFGGVYEGVLPDGRK-VAVKQLESTGQGKKEFYA-----EVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHMENS----SLDKWI
|.|| ||...  . .| ||||...  .. ... ..     |..|.  ..| | |.|.... .. .  .| |..|.     .|  .|
GSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI
Kinase LLEC_g.AA RTKE 15-75 34 3.5e-10 30.86 In-house 43-102 (293) Show / Hide 
Range on Protein: 15-75
Range on HMM: 43-102/293
Sequence Identity: 34% (21 aa)

RKVAVKQLESTGQGKKEFYAEVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHMENSSLDKW
|.|||| |.   . ..|| .|. ..  .|| |.|.||.  ... . ..||| |. ..|. |
RQVAVKTLHNH-ECHHEFVQEMTMMCKLHHPNVVHLLHVVQMKQHFMMVYEYMPGGQLEDW
Kinase LLEC_g.AA TK 3-75 18 1.5e-09 27.42 In-house 12-149 (486) Show / Hide 
Range on Protein: 3-75
Range on HMM: 12-149/486
Sequence Identity: 18% (25 aa)

FG---GVYEGVLPDGR--------------------------KVAVKQLEST-GQGKKEFYA--------------EVSILGTIH-----HWNLVKLLGF
||    ||.| . ...                          .||||.| .. .. ..|| .              |....   .     | |.|.|.| 
FGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGV

CSEGLNK------------LLVYEHMENSS----LDKW
|..| .|            ..| |.|.. .    |...
CTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDY
Kinase LLEC_g.AA Trk 17-78 33 2.4e-09 27.77 In-house 32-94 (275) Show / Hide 
Range on Protein: 17-78
Range on HMM: 32-94/275
Sequence Identity: 33% (21 aa)

VAVKQL-ESTGQGKKEFYAEVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHMENSSLDKWIYQ
|||| | . . . .|.|  |  .|    | . ||. | | .. . |.|.|.|..  | |.  |
VAVKTLKDASENARKDFQREAELLTNLQHQHIVKFYGVCTDHDPLLMVFEYMKHGDLNKYLRQ
Kinase LLEC_g.AA TKL-Unique 1-74 32 6.7e-09 27.71 In-house 8-89 (290) Show / Hide 
Range on Protein: 1-74
Range on HMM: 8-89/290
Sequence Identity: 32% (27 aa)

GGFGGVYEGVLPDGRKVAVKQLE----STGQGKKEFYAEVSILGTIH-HWNLVKLLGFCS----EGLNKLLVYEHMENSSLDK
||.| || |. . | .||.||..    |  . ..||. ||... ..| | |.|.. |.|        |  .| | .. .||..
GGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYD
Kinase LLEC_g.AA Csk 1-72 37 6.7e-09 26.56 In-house 10-82 (251) Show / Hide 
Range on Protein: 1-72
Range on HMM: 10-82/251
Sequence Identity: 37% (28 aa)

GGFGGVYEGVLPDGRKVAVKQLESTG-QGKKEFYAEVSILGTIHHWNLVKLLGFCSEGLNKL-LVYEHMENSSL
| || |  | .  .||||||..   |      | || |.  .. | |||.|.|   .  |.| .| |.| . .|
GEFGDVMQGEY-QNRKVAVKCIKCDGNGMAQAFLAEASVMTQLRHPNLVQLIGVILHQKNHLYIVMEYMSKGNL
Kinase LLEC_g.AA Sev 1-68 36 1e-08 25.01 In-house 10-86 (277) Show / Hide 
Range on Protein: 1-68
Range on HMM: 10-86/277
Sequence Identity: 36% (28 aa)

GGFGGVYEGVLPDGR-------KVAVKQLE--STGQGKKEFYAEVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHME
| || |||| . |         .||.| |   || | | ||  |  . .   | | |...| |  .    .. ||||
GAFGEVYEGQAKDIDGVGEEEQRVAIKTLRKGSTDQEKQEFLKEAHLMSKFKHPNIVCQMGVCLDNEPQYIIMEHME
Kinase LLEC_g.AA EGFR 1-54 37 1.4e-08 24.43 In-house 10-70 (258) Show / Hide 
Range on Protein: 1-54
Range on HMM: 10-70/258
Sequence Identity: 37% (23 aa)

GGFGGVYEGV-LPDGRK----VAVKQL-EST-GQGKKEFYAEVSILGTIHHWNLVKLLGFC
| || || |.  |.| .    ||.| | |.|  . ..|.  |  ... . | .||.|||.|
GAFGTVYKGIWIPEGENVKIPVAIKVLREQTGPKANEEMLDEAYVMASVDHPHLVRLLGVC
Kinase LLEC_g.AA Abl 1-72 36 1.6e-08 24.03 In-house 10-82 (252) Show / Hide 
Range on Protein: 1-72
Range on HMM: 10-82/252
Sequence Identity: 36% (27 aa)

GGFGGVYEGVLPD-GRKVAVKQLESTGQGKKEFYAEVSILGTIHHWNLVKLLGFCSEGLNKLLVYEHMENSSL
| .| |||||    .  |||| |       .|| .|  |.  ..| |||.||| |       .. |.| .  |
GQYGEVYEGVWKRHDCTVAVKTLKEDTMEVHEFLKEAAIMKEMKHPNLVQLLGVCTREPPFYIITEFMCYGNL
Kinase LLEC_g.AA TK-Unique 1-74 25 2e-08 25.31 In-house 10-94 (294) Show / Hide 
Range on Protein: 1-74
Range on HMM: 10-94/294
Sequence Identity: 25% (22 aa)

GGFGGVYEGVLPD-------GRKVAVKQLE--STGQGKKEFYAEVSILGTIH-HWNLVKLLGFCSEGL-NKLLVYEHMENSSLDK
| || |. | .          ..||||.|.  .|.. |..|  | ...  .  | |.|..|| | .   . ....|......|..
GAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQH