Gene LRR24_c-2 (S.moellendorffii)

LRR24_c-2

Species: S.moellendorffii
Alias: LRR24_c-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR24

Sequence

Name Sequence Type Origin Length Description Download
LRR24_c-2.AA Protein None 639 None Fasta, JSON
LRR24_c-2.NA RNA None 1920 None Fasta, JSON
LRR24_c-2.kin_dom Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of LRR24_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR24_c-2.AA LRRNT_2 27-69 26 4.9e-14 48.51 Pfam 1-46 (46) Show / Hide 
Range on Protein: 27-69
Range on HMM: 1-46/46
Sequence Identity: 26% (12 aa)

LSQDRDALLDFYNAVGS-AS-SNRRLGWNRSA-GAGPCDWRGIECS
...|..|||.| ... .  . ..  . || |. ....| |.|..|.
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR24_c-2.AA LRR_1 97-118 29 0.00432 15.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 97-118
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLRVLSLRS-N--RLGGPFPD--LRNC
.|..|.|.. |  .| | .|.  . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR24_c-2.AA LRR_1 120-142 29 0.00642 14.52 Pfam 1-26 (26) Show / Hide 
Range on Protein: 120-142
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLRALYLQD-N--RFSGRLPPD-FSLW
.|. |.|.. |  ...| .||. |   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR24_c-2.AA LRR_1 144-166 37 0.030904 12.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 144-166
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLLHINLAY-N--ALNGSIPTS-INSL
.| |..| . |   | |.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR24_c-2.AA LRR_1 191-213 22 0.578031 7.59 Pfam 1-26 (26) Show / Hide 
Range on Protein: 191-213
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

RLVRFSVAN-N--NLSGPVPQR-LQGF
.| . .. . |  ||.| .| . . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR24_c-2.AA LRR_1 168-190 25 1.655062 5.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 168-190
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLTTLNLEN-N--TLSGGLAPE-LSLP
.|..|.| . |   |.| . |. .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR24_c-2.AA TKL 349-612 16 4.8e-50 172.57 In-house 1-364 (364) Show / Hide 
Range on Protein: 349-612
Range on HMM: 1-364/364
Sequence Identity: 16% (67 aa)

LGKGSIGTTYKAVLED---------GSIVAVKRLKDVTAPP----------------------------SQFEHNMQLIGGLRHRNVVPLRAYYHSKDE-
.|.|. |. ||...           |  ||||..|                                   ..|  . ..  ||| |.|.. .|  . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KLLVSDYMPRGS-CSALLHGNRGAGRSPLDWPSRLRIADGAAKGLAYIHEQNG-----GTFVHGSIKSSNVLLAKDFE----------
              .| .|.|.|| .. |.            |. |.|.| ..|.|..| | .|         .|  .||.|.|. ....          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----ACVSDAGLAHLLT-------------------TNAAATSSRM--LGYRAPEVLE----------------TRKVTQKSDVYSYGVLLLELLTGRAP
    ....| ||.  ..                   .|. .|...   ... |||||.                 .. ..|.||||.|..| |.||..  
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

TQASLTDEGIDLPRWVQSVVREEWTAEVF------DLELMRYHNIEEDLVQ------------------MLQLALSCTSVAPEQRPSMRQVVETI
                  . ....  ..       .   |.... .  ..                   | .|.  | .  ||.|||. ......
------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR24_c-2.AA IRAK 344-540 30 9.3e-33 113.47 In-house 2-223 (317) Show / Hide 
Range on Protein: 344-540
Range on HMM: 2-223/317
Sequence Identity: 30% (68 aa)

ASAEVLGKGSIGTTYKAVLEDGS-IVAVKRLKDVTAPP-----SQFEH---NMQLIGGLRHRNVVPLRAYYHSKDEKLLVSDYMPRGSCSALLHGNRGAG
. . ..|.| .|. |....     |.|||.|| .  .       .|      ...   .|| |.||| .|    ..  || .||| ||  . |..  |..
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

R-SPLDWPSRLRIADGAAKGLAYIHEQN-GGTFVHGSIKSSNVLLAKDFEACVSDAGLAHLL---TTNAAATS-----SRMLG---YRAPEVLE--TRKV
   || |. |. |. |.|.|. . |.   .  . || |||.|.|| ..|..  .| ||..       . ..|.     |.  |   | .|| .   ... 
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

TQKSDVYSYGVLLLELLTGR-A
| |.|||| |. |||.|||. |
TKKTDVYSFGIVLLEVLTGCRA
Kinase LRR24_c-2.AA Pkinase 343-612 20 3.7e-29 104.16 Pfam 1-293 (293) Show / Hide 
Range on Protein: 343-612
Range on HMM: 1-293/293
Sequence Identity: 20% (61 aa)

RASAEVLGKGSIGTTYKAVLEDGSI-VAVKRLKDVTAPPSQFEH-----NMQLIGGLRHRNVVPLRAYYHSKDEKLLVSDYMPRG----SCSALLHGNRG
    ...|.|| |. ||..  . .. ||||..| ... ... ..       |.   |.| |.| |. ....||.  .| .|.. |    . ......   
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

AGRSPL--DWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEA----CVSDAGLAHLL-TTNAAATSSRM--LGYRAPEVLE-TRKVTQK
  . ..  ..    ...   ..||.|.|..    ..|  .|..|.|. .. .     ...| ||| .. . |   ....   ..|.||||.   .. ..|
WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

SDVYSYGVLLLELLTGRAPTQAS-LTDEGIDLPRWVQSVVREEWTAEVFDLELMRY------------HNIEEDLVQMLQLALSCTSVAPEQRPSMRQVV
.|..|.|..| |.|.|| | . .  .|. .|    .. . . ..  . . .  ..|            ||..|..   ...  .|  . |..||. .|..
VDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEEC---KDFIKWCLCKDPKKRPTAEQIL

ET--I
.   .
QHPWF
Kinase LRR24_c-2.AA MLK 343-541 23 2.4e-26 88.5 In-house 1-235 (291) Show / Hide 
Range on Protein: 343-541
Range on HMM: 1-235/291
Sequence Identity: 23% (56 aa)

RASAEVLGKGSIGTTYKAVLEDGS----IVAVKRLK-DVTAPPSQ-------FEHNMQLIGGLRHRN----VVPLRAYYHSKDE-KLLVSDYMPRGSCSA
    |..|.|| |  .|..         |||||| . .     |.       ||    .   |.|.|    ......  ..     ..|. |.. || . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

LLHGNRGAGR---------SPLDWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLA------KDFEACVSDAGLAHLLTTNAAATSSRMLG---
.|||.|. .             |  . ...|   |.|..| |..   . .|  .||.|.|..      ..  . ..|.|... ....  ..   . |   
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YRAPEVL---ETRKVTQKSDVYSYGVLLLELLTGRAP
..||||.   .  |.. |.||.|.||.| |.||.. |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR24_c-2.AA TKL-Unique 345-541 24 2.4e-25 86.47 In-house 1-233 (290) Show / Hide 
Range on Protein: 345-541
Range on HMM: 1-233/290
Sequence Identity: 24% (57 aa)

SAEVLGKGSIGTTYKAVLEDGSIVAVKRLKDVTAPPS-Q--FEHNMQL--IGGLR-HRNVVPLRAYYH----SKDEKLLVSDYMPRGSCSALLH-----G
  ...| |. |. ||..   |..||.|...   . .| .  .|.....  .  |. | |.| . .| .    .  .  .|..|.|.||   .||      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

NRGAGRSPLDWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKD-----FEACVSDAGLAHLLTTNAAATSSRM-----------LGYRAPEV
|  .  ..|..  |...|  .|.|. |.|  ..    |. .||||.|.  .     . . ..| ||. ..... . |...            . ..||||
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LET--RKVTQKSDVYSYGVLLLELLTGRA------P
|.    . ..||||||.|. | |..|.        |
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR24_c-2.AA TK 347-541 15 6.3e-25 79.85 In-house 5-394 (486) Show / Hide 
Range on Protein: 347-541
Range on HMM: 5-394/486
Sequence Identity: 15% (61 aa)

EVLGKGSIG---TTYKAVLEDGS--------------------------IVAVKRLK--DVTAPPSQFE----------------HNMQLIGG--LRHRN
..||.|  |   . ||. .....                           |||| ||  | ...  .|.                . |..     ..| |
KKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPN

VVPLRA-------------YYHSKDEKLLVSDYMPRGS----CSALLHGNRGAGRS--------------------------------------------
.| | .             . . .   ..|  ||| |.        |. .|. ..                                             
IVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDD

---------------------------PLDWPSRLRIADGAAKGLAYIHEQN-----GGTFVHGSIKSSNVLLAKDFE-----------ACVSDAGLA--
                           .|. . .| ..  .|.|..|.|..|     .  |||. .   |.|....             . ..| ||.  
LIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQN--FVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----HLLTTNAAATSSRMLGYR------------------------------APEVLE---------TRKVTQKSDVYSYGVLLLELLT-GRAP
    .    .      |. .|.                              |||.|.         ..| | ||||.|.|||. |..| |..|
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRR24_c-2.AA Frk 344-541 29 4.2e-23 76.64 In-house 2-202 (260) Show / Hide 
Range on Protein: 344-541
Range on HMM: 2-202/260
Sequence Identity: 29% (61 aa)

ASAEVLGKGSIGTTYKAVLEDGSIVAVKRLKDVTAPPSQFEHNMQLIGGLRHRNVVPLRAYYHSKDEKLLVSDYMPRGSCSALLHGNRGAGRSPLDWPSR
     || |  |  .    .    ||||.||  |. |  |  . |..  |||  .. | |    ..  ... . | .||    |    . ||. .  .  
QLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ-CQMQQL

LRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAH-LLTTNA----AATSSRM-LGYRAPEVLETRKVTQKSDVYSYGVLLLELLT
. .|   | |.||. .||   ..|  .   |||. ..    . | |||  |.  |     . .  |. . . |||  .. | | ||||.|.|.|| |..|
VDMAAQVAAGMAYLESQN---YIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEIIT

-GRAP
 || |
YGRMP
Pkinase_Tyr LRR24_c-2.AA Pkinase_Tyr 342-541 28 4.4e-22 75.42 Pfam 1-214 (270) Show / Hide 
Range on Protein: 342-541
Range on HMM: 1-214/270
Sequence Identity: 28% (63 aa)

LRASAEVLGKGSIGTTYKAVLE-----DGSIVAVKRLKDVTAPPSQ-----FEHNMQLIGGL-RHRNVVPLRAYYHSKDEK---LLVSDYMPRGSCSALL
..   ..||.|. |. ||...      ..  |||| ||. .| ..|     | . ...   | .| |.| | .   ...|    ..|  ||| |.    |
ITFG-KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HGNRGAGRSPLDWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAHLLTTNAAATSSRMLG-------YRAPEVLETRKVT
. .|  .. ||. .  | ..   |||..| ...|   ..|  .   |.|..... . ..| ||| .. .|     .|. |         |||.. ..| |
RKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYY-YRKRGGGKLPIKWMAPECINYGKFT

QKSDVYSYGVLLLELLT-GRAP
 ||||.|.|||. |..| |. |
TKSDVWSFGVLMWEIFTYGEQP
Kinase LRR24_c-2.AA STE 344-541 19 6.9e-20 66.99 In-house 1-267 (359) Show / Hide 
Range on Protein: 344-541
Range on HMM: 1-267/359
Sequence Identity: 19% (55 aa)

ASA-EVLGKGSIGTTYKAVLED----------------GSIVAVKRLK----------------DVTAPPS--QFEHNMQLIGGLR--HRNVVPLRAYYH
    |..|||. ||.|||.  .                | |.|.|...                . . .    |... ...   ..  | |.|    .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

SK-------DEKLLVSDYMPRGSCSALLHGNRGAGR---------SPLDWPSRLRIADGAAKG-LAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAG
 .       ||  ..  ||. ||.. ... . | |.         .... .   .|.    || |.|.|...    .|  ||..|.||     .  .| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

LAHLLTTNAA------------ATSSRM------LGYRAPEVLET------RKVTQKSDVYSYGVLLLELLTGRAP
..  || . |             ....         . ||||..        . . |.|..| | ...|..||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR24_c-2.AA Dicty4-Unclassified 444-541 36 8.5e-20 64.45 In-house 112-207 (263) Show / Hide 
Range on Protein: 444-541
Range on HMM: 112-207/263
Sequence Identity: 36% (36 aa)

LRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAHLLTTNAAATSSR-MLGYRAPEVLETRKVTQKSDVYSYGVLLLELLTGRAP
...|   |.|... |  |   |.|  |||||.|. |.| . . | |..     |   |         .||.|     .||||||||...| ||.||  |
IKYAFDIAQGMQHLHTRN---FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP
Kinase LRR24_c-2.AA Dicty4 414-541 32 1.4e-18 58.71 In-house 80-216 (277) Show / Hide 
Range on Protein: 414-541
Range on HMM: 80-216/277
Sequence Identity: 32% (45 aa)

VSDYMPRGSCSALLHG--NRGAGRSPLDWPSRLR---IADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAH----LLTTNA-AATSS
|. |||.|.   |||        . .|||| ..|   .|  ||.|... |. |   ..|  .||.| |  |.. . |.| ||.       . .. . |  
VTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN-PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTAC

RMLGYRAPEVLETRKVTQKSDVYSYGVLLLELLTGRAP
   .. ||||.  .  ..|.||||.| .| |.||. .|
GTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEP
Kinase LRR24_c-2.AA TyrKc 343-612 21 2.2e-16 42.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 343-612
Range on HMM: 1-280/280
Sequence Identity: 21% (65 aa)

RASAEVLGKGSIGTTYKAVLEDGSIVAVKRLKDVTAPPSQFEHNMQLIGGL--RHRNVVPLRAYYHSK-------DEKLLVSDYMPRGSCSALLHGNRGA
    ..|| |  |. ||...     |||| ||. .     | . ...   |  .| |.| | ..  ..       .  ..|  ||| |..   |. .|. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

GRSPLDWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAHLLTTN-------AAATS----SRM--LGYR--APEVLETRK
    | ..  | ..  .|.| .|.|..    ..|  .   |.|..... . .|| ||.  ..            ..    ..   | .|  |||.. ..|
----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VTQKSDVYSYGVLLLELLTGRAPTQASLT---DEGIDLPRWVQSVVREEWTAEVFDLELMRYHNIEEDLVQMLQLALSCTSVAPEQRPSMRQVVETI
 | ||||.|.||.. |..|  ..     .    . ... ..|..  | .  ...   . | .    .    | |. ..|    ||.||......| .
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR24_c-2.AA S_TKc 343-615 20 1.6e-15 50.87 SMART 1-231 (231) Show / Hide 
Range on Protein: 343-615
Range on HMM: 1-231/231
Sequence Identity: 20% (59 aa)

RASAEVLGKGSIGTTYKAVLED-GSIVAVKRLKDVTAPPSQFEHNMQLIGGLRHRNVVPLRAYYHSKDEKLLVSDYMPR--GSCSALLHGNRGAG-RSPL
    ...|||. |. ||..  . | |||.|..|       ...  .|.    .| |.| |  .... |.  .| .|..   |.   ... ... | |.|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWPSRLRIADGAAKGLAYIHEQNGGTFVHGSIKSSNVLLAKDFEACVSDAGLAHLLTTNAAATSSRMLGYRAPEVLETRKVTQ-KSDVYSYGVLLLELLT
.     ...   ...|.|.|...   ..|  .| .|.|| .  .  ..| ||| .| |    |    . |.|||||   . .  |.|..| |..| |.|.
PE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL-TTFCGT----PWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GRAPTQASLTDEGIDLPRWVQSVVREEWTAEVFDLELMRYHNIEEDLVQMLQLALSCTSVAPEQRPSMRQVVE------TIEQL
|. | .        .. .  . ..                        .....   |  . ||.||.  .. .        . .
GYPPFP--------QMQMMFKKIG----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR24_c-2.AA LRRK 413-541 27 3.9e-15 49.99 In-house 132-282 (351) Show / Hide 
Range on Protein: 413-541
Range on HMM: 132-282/351
Sequence Identity: 27% (42 aa)

LVSDYMPRGSCSALLHGNRGAGR----SPLDWPSRLRIADGAAKGLAYIHEQNGGT--FVHGSIKSSNVLLAKD------------FEACVSDAGLAH--
.| .|.| |. . .|| ..  |.      ..|  .|.||   |||..| | .   .  ..|   || |.|| .               | ..| |.    
MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH---NPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF

LLTTNA-AATSSRMLGYRAPEVLE---TRKVTQKSDVYSYGVLLLELLTGR-AP
  .... | ..    |..|||..    .   |.|.|.||.|..| ||||..  |
QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRR24_c-2.AA TK 578-612 22 8.1e-05 11.25 In-house 452-486 (486) Show / Hide 
Range on Protein: 578-612
Range on HMM: 452-486/486
Sequence Identity: 22% (8 aa)

HNIEEDLVQMLQL-ALSCTSVAPEQRPSMRQVVETI
| ...   .....  ..| .  ||.||...|..| .
H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR24_c-2.AA LRRK 593-614 31 0.000104 12.57 In-house 330-351 (351) Show / Hide 
Range on Protein: 593-614
Range on HMM: 330-351/351
Sequence Identity: 31% (7 aa)

SCTSVAPEQRPSMRQVVETIEQ
.| .  |..||.. |.|....|
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR24_c-2.AA Dicty4 599-614 27 0.002455 7.18 In-house 260-277 (277) Show / Hide 
Range on Protein: 599-614
Range on HMM: 260-277/277
Sequence Identity: 27% (5 aa)

PEQRPSMRQVVET--IEQ
|..|||. ....    | 
PQHRPSFEEIIQRRILEH
Kinase LRR24_c-2.AA IRAK 587-612 26 0.002646 7.76 In-house 292-317 (317) Show / Hide 
Range on Protein: 587-612
Range on HMM: 292-317/317
Sequence Identity: 26% (7 aa)

MLQLALSCTSVAPEQRPSMRQVVETI
|.|.|. |.      |..|..|....
MCQCACCCGHHRANRRCDMAWVMQQL
Kinase LRR24_c-2.AA MLK 599-612 50 0.007163 5.95 In-house 278-291 (291) Show / Hide 
Range on Protein: 599-612
Range on HMM: 278-291/291
Sequence Identity: 50% (7 aa)

PEQRPSMRQVVETI
|..|||.||.|.  
PHKRPSFRQIVQHL
Kinase LRR24_c-2.AA Dicty4-Unclassified 594-612 31 0.037674 3.12 In-house 245-263 (263) Show / Hide 
Range on Protein: 594-612
Range on HMM: 245-263/263
Sequence Identity: 31% (6 aa)

CTSVAPEQRPSMRQVVETI
| .  |  ||.| |...  
CWHNDPNKRPTMNQIIQYL
Kinase LRR24_c-2.AA Pkinase_Tyr 599-612 35 0.057678 7.28 Pfam 257-270 (270) Show / Hide 
Range on Protein: 599-612
Range on HMM: 257-270/270
Sequence Identity: 35% (5 aa)

PEQRPSMRQVVETI
||.||......| .
PEDRPTFSEIHEQL
Kinase LRR24_c-2.AA TKL-Unique 599-612 35 0.103046 2.04 In-house 277-290 (290) Show / Hide 
Range on Protein: 599-612
Range on HMM: 277-290/290
Sequence Identity: 35% (5 aa)

PEQRPSMRQVVETI
|.||||  .... .
PSQRPSFDEIIHRL
Kinase LRR24_c-2.AA LRRK 342-374 14 0.232666 0.55 In-house 1-60 (351) Show / Hide 
Range on Protein: 342-374
Range on HMM: 1-60/351
Sequence Identity: 14% (9 aa)

LRASAEVLGKGSIG-TTYKAVLED---------------------------GSIVAVKRLK
|.   . .|.|. | . |.| ...                           .. ||.| ..
LKIEEQ-IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWN