LRR3_e-2

Species: S.moellendorffii
Alias: LRR3_e-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR3

Sequence

Name Sequence Type Origin Length Description Download
LRR3_e-2.AA Protein None 796 None Fasta, JSON
LRR3_e-2.NA RNA None 2391 None Fasta, JSON
LRR3_e-2.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of LRR3_e-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR3_e-2.AA LRRNT_2 62-100 36 2e-06 23.97 Pfam 5-46 (46) Show / Hide
Range on Protein: 62-100
Range on HMM: 5-46/46
Sequence Identity: 36% (16 aa)

LAALLAIKHAFM--DA-QGALISWNETG--VGACSGSWAGIKCA
..||||.| ..   |   |.| ||| .   .. ||  | |. | 
GQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCS--WTGVTCD

LRR_1 LRR3_e-2.AA LRR_1 127-149 33 0.000391 18.83 Pfam 1-26 (26) Show / Hide
Range on Protein: 127-149
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ELRKLNLHS-N--RIEGSIPSS-ITGL
 |..|.| . |  ...|.||.| . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 151-173 33 0.03854 11.76 Pfam 1-26 (26) Show / Hide
Range on Protein: 151-173
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLRSVYLFQ-N--RLTGTIPAG-LGRS
||.. .|   |  .|||.|| . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 175-197 40 0.062723 11.01 Pfam 1-26 (26) Show / Hide
Range on Protein: 175-197
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

LMQAVDLSG-N--RLQGDIPAS-LGSS
  |  |||| |  .|.|.|| | . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 203-221 43 1.676696 5.95 Pfam 5-26 (26) Show / Hide
Range on Protein: 203-221
Range on HMM: 5-26/26
Sequence Identity: 43% (10 aa)

LNLAG-N--NLSGGIPPE-IAGS
|.| | |  ||.| |||. . . 
LDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 223-245 29 16.478494 2.43 Pfam 1-26 (26) Show / Hide
Range on Protein: 223-245
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SLITLILAR-N--GLDGEIPTT-WPDS
.| .| | . |   | |.||       
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 247-269 51 4e-06 25.73 Pfam 1-26 (26) Show / Hide
Range on Protein: 247-269
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

KLRTLDLSR-N--NLSGEIPPS-IARL
.|..||||. |  ||.|.|||| .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 271-293 33 0.044171 11.55 Pfam 1-26 (26) Show / Hide
Range on Protein: 271-293
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLTILDVAS-N--ELSGGIPGE-LGGI
||..||. . |   |.| || . . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 295-317 51 0.000109 20.8 Pfam 1-26 (26) Show / Hide
Range on Protein: 295-317
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

ALQLLDLSG-N--RLNGSIPAS-IGQL
 || ||||| |  .| |.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL

LRR_1 LRR3_e-2.AA LRR_1 319-340 33 0.810215 7.07 Pfam 1-26 (26) Show / Hide
Range on Protein: 319-340
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NLTSANFSD-N--NLSGRVPR--FVHG
||.. ..|. |  ||.| .|   | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL

Kinase LRR3_e-2.AA TKL 484-751 20 1.7e-60 207.27 In-house 1-364 (364) Show / Hide
Range on Protein: 484-751
Range on HMM: 1-364/364
Sequence Identity: 20% (80 aa)

MGKSTYGTVYKATLEN---------GNTVVVKRLRE--GIVRSQ-------------------------REFEAEVSALGRIRHTNLVALRAYYWGPKD-
 |. ..|.|||... .         |..|.||....     ..                           ..| |.  . |.|| |.| . .|   |.. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------EKLLVFDFMHGGSLAAFLHARGPETPLGWSTRMKIALGTAKGLAYLHDAEK-------MVHGNLTSSNILLDSHLN-------------
           .  .| ....||||  .||         |. |...||..|.|..|||  .        ..| .|.|.|||.|....             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AVISDYGLSRLMTSSAGSNVLA------------------TAGSQGYRAPEVSKLK----------------KATTKSDVYSFGIVLLELLTGKAPGDA
 . |.|.|||| |. | ..|  .                    |. .. |||| . .                ....|.||||||||| |.||..     
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

VSTADGGALDLPEWVSSVVKEEWTS---------EVFDVELLKGTAPSEDD--------MLNTL------QLAMNCVSASPSSRPDMNEVLRQV
                 . .... .         | | .  .||  |  ..        . ..       .|.. | .. |..|| ..|.| . 
-----------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LRR3_e-2.AA IRAK 479-674 32 1.1e-51 178.06 In-house 2-220 (317) Show / Hide
Range on Protein: 479-674
Range on HMM: 2-220/317
Sequence Identity: 32% (71 aa)

ATAEVMGKSTYGTVYKATLENGN-TVVVKRLREG----IVRSQREFEA---EVSALGRIRHTNLVALRAYYWGPKDEKLLVFDFMHGGSLAAFLHARGPE
. . ..|. ..|.||.. . |   ...||.|.|.    .  . ..| .   |. .. |.|| |.|.| .|  .. ..  ||...| .||| . |..... 
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTER-QCHCLVYPYMPNGSLEDRLWCQDGQ

TP---LGWSTRMKIALGTAKGLAYLHDAE-K--MVHGNLTSSNILLDSHLNAVISDYGLSRLM--TSSAGSNVL------ATAGSQGYRAPEVSK--LKK
.|   | | .| .|..|||.|. .||... .    ||.  |.||||| |... |.| || |    .|.  . ..       . |.  | .||  .   ..
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATTKSDVYSFGIVLLELLTG
 |.|.|||||||||||.|||
LTKKTDVYSFGIVLLEVLTG

Kinase LRR3_e-2.AA TKL-Unique 480-677 29 1.6e-38 133.45 In-house 1-233 (290) Show / Hide
Range on Protein: 480-677
Range on HMM: 1-233/290
Sequence Identity: 29% (69 aa)

TAEVMGKSTYGTVYKATLENGNTVVVKRLRE---GIVRSQREFEAEVSALGRIR-HTNLVALRAYYWG---PKDEKLLVFDFMHGGSLAAFLH-------
  .. | ..||.|||..  .|  | .|.. .      .. .||| ||. . ... | |.| . .|      .  .  .| ... ||||   ||       
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

ARGPETPLGWSTRMKIALGTAKGLAYLHDAEK-MVHGNLTSSNILLDSH-----LNAVISDYGLSRLMTSSAGSNVL--------ATAGSQGYRAPEVSK
   ....| .. |.|.|.  |.|. |||  |. . |..|.|||.|.|..     .|. |.| |||.. ...  ...            ||  ..|||| .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

L--KKATTKSDVYSFGIVLLELLTGKA------P
   .. ..||||||||||| |..|.|       |
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP

Kinase LRR3_e-2.AA MLK 478-677 27 9.3e-38 128.59 In-house 1-235 (291) Show / Hide
Range on Protein: 478-677
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

CATAEVMGKSTYGTVYKATLENGN----TVVVKRLR---EGIVRS---QREFEAEVSALGRIRHTN----LVALRAYYWGPKDEKLLVFDFMHGGSLAAF
  . |. |....| |.|..  | .    .| ||| |   . ....   |..|| |.  | ...| |     .....    |  . ..|  .. ||||. .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHAR--GPE---------TPLGWSTRMKIALGTAKGLAYLHDAEK--MVHGNLTSSNILLDS------HLNAVISDYGLSRLMTSSAGSNVLATAGSQGY
||..  ...              .  |..||  |.|..|||  ..   .|  | |.|||.|       |....|.| |.|| ....  .|   .||.  .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

RAPEV---SKLKKATTKSDVYSFGIVLLELLTGKAP
.||||   ..  | . |.||.|.|.|| |.||.. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP

Kinase LRR3_e-2.AA TK 485-677 16 1.1e-34 113.1 In-house 8-394 (486) Show / Hide
Range on Protein: 485-677
Range on HMM: 8-394/486
Sequence Identity: 16% (65 aa)

GKSTYG---TVYKATLENGN--------------------------TVVVKRLREGIVRSQREFEA--------------EVSALGRIR-----HTNLVA
|.  .|   .|||......|                          .| || |.||   ||.||..              |....   .     | |.| 
GEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVR

LRA--YYWGPK---------DEKLLVFDFMHGGS----LAAFLHARGPETP-------------------------------------------------
| .     .||            ..|  .|..|.    |  .|... |..                                                  
LYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKD

------------------------LGWSTRMKIALGTAKGLAYLHDAE-----KMVHGNLTSSNILLDSHLN-----------AVISDYGLSRL----MT
                        |   ... ...  |.|..|||.       ..||..|   |.|......           . |.|.||||     ..
HPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLA

SSAGSNVLATAGSQGYR-----------------------------APEVSK---------LKKATTKSDVYSFGIVLLELLT-GKAP
   .|.   .. |....                             |||. .          .| ||||||.|||... |..| |..|
RDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP

Kinase LRR3_e-2.AA LRRK 488-677 24 3.6e-33 114.69 In-house 11-282 (351) Show / Hide
Range on Protein: 488-677
Range on HMM: 11-282/351
Sequence Identity: 24% (67 aa)

TYG-TVYKATLEN---------------------------GNTVVVKRLREG----------------------------------IVRSQREFEAEVSA
..| .||.|....                           ...| .| .  .                                    |. |||  ||. 
GFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAFREFRHEVWI

LGRIRHTNLVALRAYYWGPKDEKLLVFDFMHGGSLAAFLH--ARGPE----TPLGWSTRMKIALGTAKGLAYLHDAE-KMVHGNLTSSNILL---D----
. . .| |.| |  .   |     .| ...  |.|  |||  .. .     . ..|... ||||  |||..|||..  . .| .|.| ||||   .    
MSHLNHPNIVSLKGFCIHP---LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHS

-----SHLNAVISDYGLSRLMTSSAGSN-VLATAGSQGYRAPEVSK---LKKATTKSDVYSFGIVLLELLTGK-AP
      | .| |.|.|.|| | .. ..  .    |  |..|||. .    .  |.|.|.||||..| ||||..  |
PNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP

Kinase LRR3_e-2.AA Dicty4-Unclassified 500-677 33 6.7e-31 103.03 In-house 22-207 (263) Show / Hide
Range on Protein: 500-677
Range on HMM: 22-207/263
Sequence Identity: 33% (63 aa)

GNTVVVKRLREGIVRSQ----REFEAEVSALGRIRHTNLVALRAYYWGP---KDEKLLVFDFMHGGSLAAFLH--ARGPETPLGWST--RMKIALGTAKG
|  | || . |.  .       .| .||  || | | ||| .. |   |   |     |  ||| | |    |      . |.       .|.|.  |.|
GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQG

LAYLHDAEKMVHGNLTSSNILLDSHLNAVISDYGLSRLMTSSAGSNVLATAGSQGYRAPEVSKLKKATTKSDVYSFGIVLLELLTGKAP
...||    ..|  . |||||.| | |. | | |.||    .   |  . ||     .||. .    . ||||||....| ||.||  |
MQHLH-TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP

Kinase LRR3_e-2.AA Pkinase_Tyr 489-677 27 1.8e-29 100.47 Pfam 12-214 (270) Show / Hide
Range on Protein: 489-677
Range on HMM: 12-214/270
Sequence Identity: 27% (58 aa)

YGTVYKATLE-----NGNTVVVKRLREGIVRSQ---REFEAEVSALGRI-RHTNLVALRAYYWGPKDE--KLLVFDFMHGGSLAAFLHAR-GPETPLGWS
.|.|||.|.      .. .| || |.||   .|   ..| .|.. .  . .| |.| | .     ..    ..|. .| .|.|  .|...  .. ||  .
FGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

TRMKIALGTAKGLAYLHDAEKMVHGNLTSSNILLDSHLNAVISDYGLSRLM-------TSSAGSNVLATAGSQGYRAPEVSKLKKATTKSDVYSFGIVLL
.  ....  |||..||..   ..|  |   |.|... . . |.| ||.|..       ... |.  |         |||. . .| ||||||.|||... 
DLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWM----APECINYGKFTTKSDVWSFGVLMW

ELLT-GKAP
|..| |. |
EIFTYGEQP

Kinase LRR3_e-2.AA Pkinase 488-677 23 6.4e-29 103.33 Pfam 11-211 (293) Show / Hide
Range on Protein: 488-677
Range on HMM: 11-211/293
Sequence Identity: 23% (49 aa)

TYGTVYKATLENGNT-VVVKRLREGIVRSQREFEA-----EVSALGRIRHTNLVALRAYYWGPKDEKLLVFDFMHGG----SLAAFLH--ARGPETPLGW
..|.|||..  . .  |.||...    ..  . ..     |.. . |..| | | |. ..   ||.  .|.... ||    .|.....  ..|. . . .
SFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFY-FSE

STRMKIALGTAKGLAYLHDAEKMVHGNLTSSNILLDSHLNA----VISDYGLSRLM-TSSAGSNVLATAGSQGYRAPEVSK-LKKATTKSDVYSFGIVLL
 .  .... ...||.|.|. .. .|  | ..|||.|.. .      |.| ||.... . . .      .|. .|.|||| .  .. ..|.|..|.|..| 
WECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILY

ELLTGKAP
|.|.|. |
EMLCGRPP

Kinase LRR3_e-2.AA RIPK 484-677 26 7.6e-29 95.42 In-house 1-227 (290) Show / Hide
Range on Protein: 484-677
Range on HMM: 1-227/290
Sequence Identity: 26% (60 aa)

MGKSTYGTVYKATLENGNTVVVKRLREGIVRS-------QREFEAEVSALGRIRHTNLVALRAYYWGPKD---EKL--LVFDFMHGGSLAAFLHARGP--
 |.   |.|.||.    ...|.|    .  .        . .   |. .. ..|. . | .      ...    ||  .|  .|  |||. |||.. |  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

ETPLGWSTRMKIALGTAKGLAYLHDAE-KMVHGNLTSSNILLDSHLNAVISDYGLSRLMTSS--AG----------SNVLATAGSQGYRAPEVSK--LKK
. |. |. |  .   .. |  |||.      |  |  .|||.|..... |.| ||.  |. |   .          .  .   |   | .||     .||
HHPDPWPLRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKK

A----TTKSDVYSFGIVLLELLTGKAP
.    |.|.|||||.||. |.||.| |
PIKVVTPKYDVYSFAIVMWEVLTQKHP

Kinase LRR3_e-2.AA Dicty4 554-677 32 2.3e-27 88.45 In-house 83-216 (277) Show / Hide
Range on Protein: 554-677
Range on HMM: 83-216/277
Sequence Identity: 32% (43 aa)

FMHGGSLAAFLHA----RGPETPLGWSTRMK---IALGTAKGLAYLHDAE-KMVHGNLTSSNILLDSHLNAVISDYGLSRLMTSSA--GSNVLATAGSQG
.|. |.|.  ||.      ....| |... .   .|. .|.|...||      .|  | |.|.| | .... ..| |||..|      . |  ...|. .
YMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPC

YRAPEVSKLKKATTKSDVYSFGIVLLELLTGKAP
. ||||   .  . |.||||||||| |.||...|
WMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEP

Kinase LRR3_e-2.AA S_TKc 478-754 20 5.7e-26 93.52 SMART 1-231 (231) Show / Hide
Range on Protein: 478-754
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

CATAEVMGKSTYGTVYKATLEN-GNTVVVKRLREGIVRSQREFEAEVSALGRIRHTNLVALRAYYWGPKDEKLLVFDFMHG--GSLAAFLHARGPETP--
    .. || ..|.|||..  . |  | .|...       . .. |.. | . .| |.| |  ..    |.  .|.... |  |.|  ... ||.. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LGWSTRMKIALGTAKGLAYLHDAEKMVHGNLTSSNILLDSHLNAVISDYGLSRLMTSSAGSNVLATAGSQGYRAPEVSKLKKATT-KSDVYSFGIVLLE
 .   .  ...  ....|.|.|.  . .|  |  .|||||.  .  |.| ||.|..            |.  |.||||    . .. |.|..|.|..| |
PFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLTGKAPGDAVSTADGGALDLPEWVSSVVKEEWTSEVFDVELLKGTAPSEDDMLNTLQLAMNCVSASPSSRPDMNEVLR------QVESV
.|.|. | .     .   ...                                   ... ..|    |. ||   |.|.      . . .
MLCGYPPFP----QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LRR3_e-2.AA CZAK 543-677 31 6.6e-26 91.14 In-house 73-221 (279) Show / Hide
Range on Protein: 543-677
Range on HMM: 73-221/279
Sequence Identity: 31% (48 aa)

GPKDEKLLVFDFMHGGSLAAFLHARGPETPLGWSTRMKIALGTAKGLAYLHD--AE-KMVHGNLTSSNILLDSHLN-------------AVISDYGLSRL
|| . .  |  .| ||||  .|  .        . ....|.  |.|  ||||   .   .|  |.|.|||||. .              . |.|.||||.
GP-NHHCIVMEWMGGGSLRRLLTDHYFYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSRE

MTSSAGSNVLATAGSQGYRAPEVSKLKKATTKSDVYSFGIVLLELLTGKAP
|   . .   .| |.  . |||. |    | |.||||||..| ...|.  |
MMEQP-FEMTQTMGCLCWMAPECFKGENYTEKVDVYSFGMILWCIITCDQP

Kinase LRR3_e-2.AA TyrKc 478-751 21 1.2e-16 46.39 SMART 1-280 (280) Show / Hide
Range on Protein: 478-751
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

CATAEVMGKSTYGTVYKATLENGNTVVVKRLREGIVRSQREFEAEVSALGRI--RHTNLVALRAYYWGPK------DEKLLVFDFMHGGSLAAFLHARGP
    .. |   .|.|||.|.    .| || |.|.    ...|  | . . ..  .| |.|.| ..   ..      .  ..|. .| .|.|  .|....|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

ETPLGWSTRMKIALGTAKGLAYLHDAEKMVHGNLTSSNILLDSHLNAVISDYGLSRLMTSS----AGSNVLATAGSQGYR--------APEVSKLKKATT
.  | ...  ....  |.| .|||.  . .|  |   |.|... . . ||| ||||  ..     . . .  .....| .        |||. . .| ||
K--LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSFGIVLLELLT-GKAPGDA-----VSTAD-------GGALDLPEW---VSSVVKEEWTSEVFDVELLKGTAPSEDDMLNTLQLAMNCVSASPSSR
||||.|||... |..| |. |        .| ..       |. .. |.    .|                      .        |.   |  . |..|
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------FVCCPDEMYQIMKQCWHEDPEDR

PDMNEVLRQV
| ..|. .. 
PTFSEIHECF

Kinase LRR3_e-2.AA Dicty4 733-753 26 0.005226 6.07 In-house 255-277 (277) Show / Hide
Range on Protein: 733-753
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CVSASPSSRPDMNEVLRQ--VES
| . .|..|| ..|.. .   |.
CWDHDPQHRPSFEEIIQRRILEH

Kinase LRR3_e-2.AA TK 728-751 25 0.013812 3.63 In-house 463-486 (486) Show / Hide
Range on Protein: 728-751
Range on HMM: 463-486/486
Sequence Identity: 25% (6 aa)

QLAMNCVSASPSSRPDMNEVLRQV
.| . | .. |. ||.. ....| 
DLMQQCWHYDPEDRPTFSQLHEQL

Kinase LRR3_e-2.AA Dicty4-Unclassified 728-751 29 0.015403 4.47 In-house 240-263 (263) Show / Hide
Range on Protein: 728-751
Range on HMM: 240-263/263
Sequence Identity: 29% (7 aa)

QLAMNCVSASPSSRPDMNEVLRQV
.|   | . .|  || ||..    
KLIKWCWHNDPNKRPTMNQIIQYL

Kinase LRR3_e-2.AA MLK 728-751 20 0.024539 4.07 In-house 268-291 (291) Show / Hide
Range on Protein: 728-751
Range on HMM: 268-291/291
Sequence Identity: 20% (5 aa)

QLAMNCVSASPSSRPDMNEVLRQV
.| ..| .. |..||.. ... . 
KLMKQCWNQDPHKRPSFRQIVQHL

Kinase LRR3_e-2.AA IRAK 727-751 32 0.112117 1.92 In-house 293-317 (317) Show / Hide
Range on Protein: 727-751
Range on HMM: 293-317/317
Sequence Identity: 32% (8 aa)

LQLAMNCVSASPSSRPDMNEVLRQV
.|.|  |. .    |.|| .|. | 
CQCACCCGHHRANRRCDMAWVMQQL

Kinase LRR3_e-2.AA Pkinase_Tyr 728-751 29 7.150286 0.19 Pfam 247-270 (270) Show / Hide
Range on Protein: 728-751
Range on HMM: 247-270/270
Sequence Identity: 29% (7 aa)

QLAMNCVSASPSSRPDMNEVLRQV
.| . |  . |. || . |...| 
DLMKQCWHYDPEDRPTFSEIHEQL