Gene LRR6_b (S.moellendorffii)

LRR6_b

Species: S.moellendorffii
Alias: LRR6_b
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR6

Sequence

Name Sequence Type Origin Length Description Download
LRR6_b.AA Protein None 1006 None Fasta, JSON
LRR6_b.NA RNA None 3021 None Fasta, JSON
LRR6_b.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of LRR6_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRR6_b.AA LRR_1 139-162 27 22.793734 1.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 139-162
Range on HMM: 1-26/26
Sequence Identity: 27% (8 aa)

RLKKLVLQG-V--HLT-EAMFHSI-FSSL
.|..| |.|    .|| .  ...  | .|
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 164-187 31 1.909217 5.75 Pfam 1-26 (26) Show / Hide 
Range on Protein: 164-187
Range on HMM: 1-26/26
Sequence Identity: 31% (9 aa)

ELQDLTIQS-N--SLS-NTTIPAS-LCSL
 || | ... |  .|. .  || | . .|
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 189-211 44 1.434737 6.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 189-211
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

SLVHLDLSS-N--QHGGEIPPC-LSVL
.| |||||. |  .  |.|||  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 213-234 40 0.001134 17.19 Pfam 1-26 (26) Show / Hide 
Range on Protein: 213-234
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLQELRLSD-N--LLQGSIPY--LGNF
.||.| ||. |   |.|.||   . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 236-258 33 0.593242 7.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 236-258
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

QMQQLVLDF-N--QLSGPFPAS-LCNI
. | | |.  |  .|.| .| | . | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 261-283 29 0.374108 8.26 Pfam 1-26 (26) Show / Hide 
Range on Protein: 261-283
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

TIVTLDLSM-N--RLS-SLLPDCVSGI
.. .||||  |  .|. .. |.|  . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 284-305 40 0.409713 8.12 Pfam 3-26 (26) Show / Hide 
Range on Protein: 284-305
Range on HMM: 3-26/26
Sequence Identity: 40% (10 aa)

QNLFLRY-N--QLTGPLPPTLFAHN
| | |.. |  .||| .||  | . 
QHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 306-327 25 7.965319 3.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 306-327
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SSQTIELSW-N--QFTGPLPE--IGDA
. |.. ||  |  ..|| .|.  .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 354-376 44 7e-06 25.03 Pfam 1-26 (26) Show / Hide 
Range on Protein: 354-376
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NMRVLDLSN-N--QFTGSIPKA-FGNC
| ..||||. |  ..||.||.  | |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 378-400 25 0.12566 9.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 378-400
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RMARLSIDN-N--ELSGEIPST-LGAL
.  .|.... |   |.|.||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 426-448 29 0.06072 11.06 Pfam 1-26 (26) Show / Hide 
Range on Protein: 426-448
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

YLMVLDLAS-N--SLSGELGEW-IYQL
 | .||| . |  .|.|.. .. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 450-472 33 0.016039 13.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 450-472
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

FLNVLSIGS-N--NFVGDIPVE-FGNF
 | .|.... |  |..|.|| . | |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 475-497 29 1.388903 6.24 Pfam 1-26 (26) Show / Hide 
Range on Protein: 475-497
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLMAIDLSE-N--TFSGTLPAQ-FSFP
.|  .|||  |   ..|..|   |   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 535-554 37 0.023224 12.54 Pfam 4-26 (26) Show / Hide 
Range on Protein: 535-554
Range on HMM: 4-26/26
Sequence Identity: 37% (9 aa)

YLDMSG-N--SFQGNIPDT-LGNF
.||.|| |  ...|.||.  . |.
HLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 556-578 33 0.000566 18.26 Pfam 1-26 (26) Show / Hide 
Range on Protein: 556-578
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLSYLDLSR-N--QFVGQVPHT-LGSL
.| .||||. |  ...|..|.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 580-602 37 0.029531 12.17 Pfam 1-26 (26) Show / Hide 
Range on Protein: 580-602
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLQALDLSS-N--RLSGSMPRE-LTEI
 || ||||. |  .|.|. | . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_b.AA LRR_1 604-625 29 2.024117 5.66 Pfam 1-26 (26) Show / Hide 
Range on Protein: 604-625
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

QLSYFNVSY-N--NLTGAVPQ--GAQF
.| . ..|. |  |||| .|     ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR6_b.AA IRAK 719-917 34 1.4e-50 174.4 In-house 1-219 (317) Show / Hide 
Range on Protein: 719-917
Range on HMM: 1-219/317
Sequence Identity: 34% (75 aa)

FNKDNIVDKGGCSTIYRGVLRDGQ-TVAVK----VYKLSDHTGEEQFIA---EYNSLKDLRHRNIVRIIEWCSESKLKALVFKFMDNGSLEKQLHELHGS
|.|||   .||  ..|||...    ..|||    . ..|    ...| .   |  ..  .|| ||| .   |.|.    ||. .| ||||| .|. . |.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

N----LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIAR-------NLRLESSMHWESKLKGSIGYVAPEYGS--DG
.    |.|  |  . .| |... .||.    | ||||.|||.||| |||.... ..||| .|       ... ....   |...|.  | .||.     |
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCT-PIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

TMTTAADVYSYGIVILETLT
  |.  |||| |||.||.||
QLTKKTDVYSFGIVLLEVLT
Kinase LRR6_b.AA TKL 725-921 21 1.7e-49 170.73 In-house 1-288 (364) Show / Hide 
Range on Protein: 725-921
Range on HMM: 1-288/364
Sequence Identity: 21% (65 aa)

VDKGGCSTIYRGVLRD---------GQTVAVKVYKL--SDHTGE-------------------------EQFIAEYNSLKDLRHRNIVRIIE--------
. .|| ...|.|..|          |..||||..|   .| . .                         .... | .... ||| |||...         
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-WCSE----SKLKALVFKFMDNGSLEKQLHELHGSNLPWTVRMNVVQGVANALSYLHEEA--ASTGP--IIHRDIKPANIFLDQNME-------------
 .| .    ..  ..|  ....|||. .||        | .|.. ....| ...||| .   ..| .  |||||.|..||..|.|..             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AHLGDFGIARNLRLESSMHWESK-----------------LKGSIGYVAPEY----------------GSDGTMTTAADVYSYGIVILETLTRIRP
 . ..|||..|..  ...|   ..                   |.... |||                    .. ....||||.|||. | ||| ||
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRP
Kinase LRR6_b.AA Pkinase 719-918 23 1.3e-36 130.58 Pfam 1-208 (293) Show / Hide 
Range on Protein: 719-918
Range on HMM: 1-208/293
Sequence Identity: 23% (50 aa)

FNKDNIVDKGGCSTIYRGVLRDGQT-VAVKVYKLSDHTGEEQFIA-----EYNSLKDLRHRNIVRIIEWCSESKLKALVFKFMDNG----SLEKQLH-EL
. .  .. .|. .. |... .. .  ||||. |.. |. ... ..     |   .| |.| ||||...|. ...   .|. ....|    .|   .. . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HGSN-LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEA----HLGDFGIARNLRLESSMHWESKLKGSIGYVAPEYGS-DGTMTT
||.  ... .  ...  .. .| |.|..      |||||.||.||..|.|..     ...|||.|. .. . . .  . . |...|.|||    .   ..
HGCFYFSEWECKFYMYQILRGLEYCHSM-----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

AADVYSYGIVILETLTR
..|..|.|... | |..
KVDMWSCGCILYEMLCG
Kinase LRR6_b.AA TKL-Unique 723-921 27 5.1e-33 113.83 In-house 3-233 (290) Show / Hide 
Range on Protein: 723-921
Range on HMM: 3-233/290
Sequence Identity: 27% (64 aa)

NIVDKGGCSTIYRGVLRDGQTVAVKVYK-LSDHTGE--EQFIAEYNSLKDLR-HRNIVRIIEWCS----ESKLKALVFKFMDNGSLEKQLHE--------
| .  ||....|.|. | |  ||.|. . ..|   |  . |. | | .| |. | |||... .|       .   .|  ... ||| . ||         
NKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

LHGSNLPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQN-----MEAHLGDFGIARNLRLESSMHWE-------SKLKGSIGYVAPEYG
   ..|.. .|.. .. .| .. ||| . .   ||||||.|. |. .|.|     . . . |||.....  .. |          .  .||. ..|||  
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEP---PIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

SD--GTMTTAADVYSYGIVILETLTRIR------P
..   . .. .||||.|||  | .|| .      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR6_b.AA RIPK 725-921 29 1.5e-31 104.8 In-house 1-227 (290) Show / Hide 
Range on Protein: 725-921
Range on HMM: 1-227/290
Sequence Identity: 29% (68 aa)

VDKGGCSTIYRGVLRD-GQTVAVKVYK-LSDHTG-----EEQFIAEYNSLKDLRHRNIVRIIEWCSES------KLKALVFKFMDNGSLEKQLHELHG--
| .|| .. .. . |. |  ||.|... .  ||      ... . |   .. ||...||.|   | .       || ..| ..| ||||.. ||      
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

-SNLPWTVRMNVVQGVANALSYLHEEAASTG-PIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLESSMH----------WESKLK-GSIGYVAPEYGS-
   .|| .|   .. .. .  |||    | . |||||| ||.|| .| |. . . ||| | ...  .|.            .||.. | . | .||    
HHPDPWPLRCRMIHEISCGMCYLH----SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRT

-DGTM----TTAADVYSYGIVILETLTRIRP
         |.. ||||..||. | ||.. |
DNKKPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase LRR6_b.AA STE 719-914 20 3e-25 86.16 In-house 1-260 (359) Show / Hide 
Range on Protein: 719-914
Range on HMM: 1-260/359
Sequence Identity: 20% (57 aa)

FNKDNIVDKGGCSTIYRGVLRD----------------GQTVAVKVYKLSD-----------------HTGEEQFIAEYNSLKDLR--HRNIVRIIEWCS
. .  .. ||.. | |... ..                |. .|.|. .|..                 |. ..|.. | . .|...  | |||. .  . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

--------ESKLKALVFKFMDNGSLEKQLHELHGSNLP------------WTVRMNVVQGVANA-LSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLG
        ...|  ..  .||.|||.. ... .| . |             ..   ... .  . |.|||.       |||||||||||.|     . | 
KEGHNHKNDDELW-ICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-----IIHRDIKPANILL-----VKLC

DFGIARNLRLES-------------SMHWES-KLKGSIGYVAPEYGS------DGTMTTAADVYSYGIVILE
|||.. .|  ..             .|  ..  . |.  . |||  .      |.  .| .|..| |..|.|
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIE
Kinase LRR6_b.AA RAF 743-923 27 6.7e-24 74.12 In-house 23-223 (282) Show / Hide 
Range on Protein: 743-923
Range on HMM: 23-223/282
Sequence Identity: 27% (56 aa)

TVAVKVYKLSDHTGEEQFIA------EYNSLKDLRHRNIVRIIEWCSESK--LKALVFKFMDNGSLEKQLHELHG-SNLPWTVRMNVVQGVANALSYLHE
.||||. ...| |  ||. |      |   .|  || ||.    . |. .    | | .. .  || . .|.     ..     ... . |. ...||| 
DVAVKMLNVNDPT-PEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQETREKFDMHWLIDISRQVCQGMDYLHA

EAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLES--SMHWESKLKGSIGYVAPEYGS--------------DGTMTTAADVYSYGIVILETLT
       |||||.|  ||||.  |    |||| ..  ...|    .    . ..| . |||                 .   .   ||||.|||. | .|
KN-----IIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQDENPYSFQSDVYSFGIVMYELMT

RIRPT-S
|  |. .
RHMPYGC
Kinase LRR6_b.AA MLK 734-918 25 1.8e-23 78.33 In-house 16-232 (291) Show / Hide 
Range on Protein: 734-918
Range on HMM: 16-232/291
Sequence Identity: 25% (56 aa)

YRGVLRDGQT-----VAVKVYKL------SDHTGEEQFIAEYNSLKDLRHRN----IVRIIEWCSES-KLKALVFKFMDNGSLEKQLHEL--------HG
..|. | ...     |||| ..       .  .  ..|  | . |. |.|.|    |...   |... .  ..|  ....|||   ||.         |.
WKGRWR-NKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANHN

SN----LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQ------NMEAHLGDFGIARNLRLESSMHWE--SKLKGSIGYVAPEY---G
 .     .  . ||    .|....|||..|    ||||||.|. || .|.      .. .   |||..| .   ..|. .   . .|.  . |||     
QKNDRVYDHDHAMNWALQCARGMHYLHSMAPK--PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDW---HQMC-TNMMSNAGTYAWMAPEVIQQF

SDGTMTTAADVYSYGIVILETLTR
  .. . ..||.|.|.|. | |||
RCEKYSEKCDVWSWGVVLWEMLTR
Kinase LRR6_b.AA Src-Echino1 720-917 28 4.8e-23 76.44 In-house 2-192 (252) Show / Hide 
Range on Protein: 720-917
Range on HMM: 2-192/252
Sequence Identity: 28% (56 aa)

NKDNIVDKGGCSTIYRGVLRDGQTVAVKVYKLSDHTGEEQFIAEYNSLKDLRHRNIVRIIEWCSESKLKALVFKFMDNGSLEKQLHELHGSNLPWTVRMN
  |. . || |. ...||      ||||  |      . .|.|| | .| .||..||.|   ||...   .| . | ||.|.. | . .. ..  |  ..
RMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKT-MSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHVKMTTLID

VVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLESSMHWESKLKGSIGYVAPEYGSDGTMTTAADVYSYGIVILETLT
.   .|  . || .       ..|||.   |. ...     . ||| || .. .  .  .   |  | . |||    |  |  .||.|.||.. | .|
MGAHIASGMDYLGSKN-----VVHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQ-GAKLPIKWTAPEAALYGRFTIKSDVWSFGILMTEMVT
Kinase LRR6_b.AA Ciliate-E2 719-921 17 8e-23 75.16 In-house 1-295 (365) Show / Hide 
Range on Protein: 719-921
Range on HMM: 1-295/365
Sequence Identity: 17% (52 aa)

FNKDNIVDKGGCSTIYRG-VLRDG-----------------------QTVAVKVYKLSDHTGEEQFIAEYN-------------SLKDLRHRNIVRIIEW
... ..  .|. ...|.. | ...                       . .|.|..| ..    .| | ...              |. | | ||....|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CS--ESKLKALVFKFMDNGSLEK--------QLHELH-GSNLPWTVRMNVVQGVAN---------------ALSYLHEEAASTGPIIHRDIKPANIFLDQ
      .   ||. . . |.|..        ..||.. . .. .  . .. . ...               || |||..    ..|||||||| ||..  
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSK----NNIIHRDIKPENILF--

NMEAHLGDFGIARNLRLE-------SSMHWESKLK-----------------------GSIGYVAPEYGSDGT---------MTTAADVYSYGIVILETL
     . |||.....  .       . . |    |                       |. ||.|||  . .           ....|..| |... | |
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML

TRIRP
.  .|
FGKPP
Kinase LRR6_b.AA Pkinase_Tyr 732-918 25 1.1e-19 67.34 Pfam 14-210 (270) Show / Hide 
Range on Protein: 732-918
Range on HMM: 14-210/270
Sequence Identity: 25% (53 aa)

TIYRGVLR-----DGQTVAVKVYKLSDHTGEEQ-----FIAEYNSLKDL-RHRNIVRIIEWCS-ESKL--KALVFKFMDNGSLEKQLHEL--HGSNLPWT
..|.|...     ....||||. |  ... .||     |..| . .| | .| |||| .  |. ...     .|. .| .|.| . |..    . .|.  
EVYKGTWKGDPDNTKIPVAVKMLK--EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMK

VRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLESSM-HWESKLKGSIGYVAPEYGSDGTMTTAADVYSYGIVILE
   .  . .|....||..       .||||.   |. .. |. .  .||| || .  ..   .  .. |  |   |||  ..|  ||. ||.|.|... |
DLLQMCWQIAKGMEYLESKN-----CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWE

TLTR
 .|.
IFTY
Kinase LRR6_b.AA LRRK 789-921 26 5.8e-18 60.11 In-house 131-282 (351) Show / Hide 
Range on Protein: 789-921
Range on HMM: 131-282/351
Sequence Identity: 26% (42 aa)

ALVFKFMDNGSLEKQLHELHGSN-------LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFL---D---------QNMEAHLGDFGIARN
..|  ....|.| . ||. . .        ..|...  ..  .| .. |||    .. |||||| |. ||.|   .         ... |...|||| | 
CMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-

LRLESSMHWE--SKLKGSIGYVAPEYGSDG---TMTTAADVYSYGIVILETLTRI-RP
.   .. | .  ... | .|..|||   ..   . |. .|.||.|... | |||  .|
MF--QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRR6_b.AA S_TKc 719-977 21 5.9e-18 66.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 719-977
Range on HMM: 1-231/231
Sequence Identity: 21% (58 aa)

FNKDNIVDKGGCSTIYRGVLRD-GQTVAVKVYKLSDHTGEEQFIAEYNSLKDLRHRNIVRIIEWCSESKLKALVFKFMDN--GSLEKQLHELHG----SN
. . ... ||. .. |... .. |. ||.|. |       |... | . ||  .| |||...... . .   .|. ..|.  |.| . ...  .    . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLESSMHWESKLKGSIGYVAPEYGSDGTMTT-AADVYSYGI
.|  .   ... ...|| |.|.       |||||.||.||.||.  .  ..|||.|| |         . . |.  |.|||       .. ..|..| |.
FPE-HARFYMYQICCALEYCHSHG-----IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

VILETLTRIRPTSGTLKDISLRSWVESHLVEGRLEDVLDPVLRQDSTAERSIDAVAR-IGLVCSHPIA
.. | |..  | . ... .  .           . | ..  |. | .   ..  . .   .. .||  
ILYEMLCGYPPFP-QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR6_b.AA TyrKc 719-990 20 2.4e-16 41.47 SMART 1-280 (280) Show / Hide 
Range on Protein: 719-990
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FNKDNIVDKGGCSTIYRGVLRDGQTVAVKVYKLSDHTGEEQFIAEYNSLKDL--RHRNIVRIIEWCSES-------KLKALVFKFMDNGSLEKQLHELHG
  .. .   |   ..|.|...  ..||||. | .    .| |. | . .. |  .| ||||..  |...       .   .|. .|..|.| . |.. ..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

SNLPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNLRLE-------SSMHWES--KLK--GSIGYVAPEYGSDGT
  |..    .    .|.  .|||.      ..||||.   |. .. |  .  .||| .|..  .       .  .  .    |    |   |||   .|.
K-LCMKDLLSFCWQIACGMEYLHSK-----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

MTTAADVYSYGIVILETLTRIRPTSGT-----LKDISLRSWVESHLVEGRLEDVLDPVLRQDSTAERSIDAVARIGLVCSHPIAAARPRMGQVSAIL
 ||. ||.|.|... | .|.  .         .... .. .|..     . .... | .   .   .  |.. .| . | |  .. ||.. ..  ..
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MS--F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LRR6_b.AA LRRK 719-751 14 0.035728 3.47 In-house 1-61 (351) Show / Hide 
Range on Protein: 719-751
Range on HMM: 1-61/351
Sequence Identity: 14% (9 aa)

FNKDNIVDKGGCS-TIYRGVLRD---------------------------GQTVAVKVYKL
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LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNR