Gene LRR8_d-2 (S.moellendorffii)

LRR8_d-2

Species: S.moellendorffii
Alias: LRR8_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_d-2.AA Protein None 989 None Fasta, JSON
LRR8_d-2.NA RNA None 2970 None Fasta, JSON
LRR8_d-2.kin_dom Protein Kinase Domain None 187 None Fasta, JSON

Protein domain

Protein domains of LRR8_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_d-2.AA LRRNT_2 51-90 43 7.4e-11 38.18 Pfam 1-46 (46) Show / Hide 
Range on Protein: 51-90
Range on HMM: 1-46/46
Sequence Identity: 43% (20 aa)

LLDDQHVLLLTKASLQ--DP-LEQLKGWTNR---SSICSWRGVTCD
. ||   ||  |.||.  || . .|. |..    |. |||.|||||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8_d-2.AA LRR_1 96-118 44 0.002185 16.18 Pfam 1-26 (26) Show / Hide 
Range on Protein: 96-118
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

VLEVLDLSD-N--NLEGGIPLS-VSSC
 |..||||. |  ||.| || |   ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 120-135 47 0.428767 8.05 Pfam 1-19 (26) Show / Hide 
Range on Protein: 120-135
Range on HMM: 1-19/26
Sequence Identity: 47% (9 aa)

NLVTLNLSK-N--SLSGTI
|| .|.||  |  .|.|.|
NLQHLDLSGCNCCNLTGHI
LRR_1 LRR8_d-2.AA LRR_1 142-164 37 0.156706 9.6 Pfam 1-26 (26) Show / Hide 
Range on Protein: 142-164
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KLNALDLSH-N--QLHGGIPLA-IGRS
.|  ||||. |  .| | ||   .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 166-191 44 0.000103 20.89 Pfam 1-26 (26) Show / Hide 
Range on Protein: 166-191
Range on HMM: 1-26/26
Sequence Identity: 44% (13 aa)

ALEKLDLSF-N--NLSGEGEIPRDLFSKL
 |..||||  |  ||.|.  || . | .|
NLQHLDLSGCNCCNLTGH--IPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 193-215 25 0.570572 7.61 Pfam 1-26 (26) Show / Hide 
Range on Protein: 193-215
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLENVSLAE-N--YFSGTIPAS-LGSS
.|.  .|   |   ..|.|| | . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 217-239 44 0.001105 17.23 Pfam 1-26 (26) Show / Hide 
Range on Protein: 217-239
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

LIRHLDLHN-N--NLTGEIPSG-VCQL
 ..|||| . |  ||||.||..   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 241-263 29 1.219747 6.44 Pfam 1-26 (26) Show / Hide 
Range on Protein: 241-263
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

DLQVILLAI-N--KFEGEIPHC-LGAL
 ||.. |   |  ...|.||.  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 265-287 40 0.007454 14.29 Pfam 1-26 (26) Show / Hide 
Range on Protein: 265-287
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ELKILDVSE-N--NLSGAIPPE-LGMM
 |..||.|  |  ||.| |||. .  .
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 289-311 40 0.032978 12.0 Pfam 1-26 (26) Show / Hide 
Range on Protein: 289-311
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

SLERLLIHT-N--NLAGRIPPQ-LGNL
.|..| .   |  || | |||  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 313-335 25 0.048375 11.41 Pfam 1-26 (26) Show / Hide 
Range on Protein: 313-335
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

LLESFDVAY-N--RLEGVIPEE-LGGM
 |.. |. . |  .|.| ||.. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 337-359 25 7.226245 3.7 Pfam 1-26 (26) Show / Hide 
Range on Protein: 337-359
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

ALSSFHLAS-N--KLTGEFPRW-LAEH
 | . .| . |  .|||..| . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 361-383 33 0.282961 8.69 Pfam 1-26 (26) Show / Hide 
Range on Protein: 361-383
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

NVSSITLNS-N--SLTGDLPPD-FGSR
|  .. |.. |  .|||..||. | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 385-407 33 0.010934 13.7 Pfam 1-26 (26) Show / Hide 
Range on Protein: 385-407
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALRSVDLSQ-N--HFTGKLPPA-LCQN
 |.. |||  |  ..||..||  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 409-431 18 0.552344 7.66 Pfam 1-26 (26) Show / Hide 
Range on Protein: 409-431
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

SLEYLAALN-N--QFSGDLPVQ-LQQC
.|..|   . |  ...|..|   . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 433-455 37 2.855581 5.13 Pfam 1-26 (26) Show / Hide 
Range on Protein: 433-455
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLDRLRLDD-N--FLTGSVHFS-QSNV
|| .| |.. |   |||... |   | 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 476-498 37 0.010313 13.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 476-498
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

MLTILDLSF-N--RLTGELPAV-LETS
 |..||||  |  .|||..|   .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 500-522 25 0.01221 13.53 Pfam 1-26 (26) Show / Hide 
Range on Protein: 500-522
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLVKINLAS-N--RLSGTLPLQ-LGQL
.| ...| . |  .|.|..|   . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 524-546 37 0.001266 17.02 Pfam 1-26 (26) Show / Hide 
Range on Protein: 524-546
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLTDLDLSS-N--NFVGDVPAL-ISGC
||. ||||. |  |..|..|   . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 548-563 31 0.910675 6.89 Pfam 1-19 (26) Show / Hide 
Range on Protein: 548-563
Range on HMM: 1-19/26
Sequence Identity: 31% (6 aa)

SLITLNLSR-N--SFQGRL
.| .|.||. |  ...| .
NLQHLDLSGCNCCNLTGHI
LRR_1 LRR8_d-2.AA LRR_1 570-592 33 0.052636 11.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 570-592
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

KLSTLDVSH-N--GLHGEIPLA-IGQS
.| .||.|. |   | |.||   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_d-2.AA LRR_1 594-616 37 0.017565 12.97 Pfam 1-26 (26) Show / Hide 
Range on Protein: 594-616
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLLKLDLSY-N--DLSGSVPAF-CKKI
|| .||||. |   |.|..|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR8_d-2.AA TKL 710-966 21 1.8e-56 193.94 In-house 1-364 (364) Show / Hide 
Range on Protein: 710-966
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

ICRGR-NNVYKGVLKG---------GIRVAVKEVQSED--------------------------HSHVAEFEAEVA-TLGNIRHRNVVKFLASCTNKRS-
| .|.   ||||...|         |  ||||   |..                           |.  .|| |..  . ..|| |.|.|...|.. .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------HLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITGIAEGLAYLHHDYG-----PKVVHRDVKCDNILLDAEMK------------
            . .|.|..| |.|...||          |..|. .. .|| |..||| .       |...||| | .|||.|  ..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PRLGDFGLAKLLRENKPSTASK------------------LAGTHGYIAPEYA-----YT-----------LKVDERADVYSFGIVVLEVLTGKMATW
  . ..||||.. . ... .....                    || .. |||       ||           .. .|..||||||||  |.||..    
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

RDATNDLDLVEWV---------KLMPVEELALEMG----------AEEQCYKLVLEIALACAEKSPSLRPTMQIVVDRL
     |..  ...         ..  .. | ...            ...| . . ...  | .  |. ||..| ...||
--PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR8_d-2.AA IRAK 705-901 34 1.6e-44 154.26 In-house 2-220 (317) Show / Hide 
Range on Protein: 705-901
Range on HMM: 2-220/317
Sequence Identity: 34% (75 aa)

SKDNLICRGR-NNVYKGVLKGGI-RVAVK----EVQSEDHSHVAEFEA---EVATLGNIRHRNVVKFLASCTNKRSHLLVYEFMPLGNLRDLLHGKMARS
.|||.|  |    ||.|..|.    .|||    .. ..  .|  .| .   |. ..  .|| |.| ... ||    | |||..|| | |.| |..  .  
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

F--SLGWDKRVEIITGIAEGLAYLHHDYGPK--VVHRDVKCDNILLDAEMKPRLGDFGLAKL-----LRENKPS---TASKLAGTHGYIAPEYAY--TLK
    | | .|..|  |.| |. .|| . .|.  . |.|.|  |||||. . | ..||||.        .|  ..    .|.. ||  | .||. .  . .
PPKPLSWHQRCSICWGTACGIQFLHQN-HPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

VDERADVYSFGIVVLEVLTG
   . ||||||||.||||||
LTKKTDVYSFGIVLLEVLTG
Kinase LRR8_d-2.AA TK 717-966 14 1.1e-38 126.8 In-house 18-486 (486) Show / Hide 
Range on Protein: 717-966
Range on HMM: 18-486/486
Sequence Identity: 14% (68 aa)

VYKGVLKGG--------------------------IRVAVKEVQSEDHSHVAEFEA--------------EVATLGNIR-----HRNVVKFLASCTNKRS
|||| ..|.                          ..|||| . ..|... .||..              |.. .   .     | |.|.... || ...
VYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVCTQGEP

------------HLLVYEFMPLGN----LRDLLHGKMARSFS----------------------------------------------------------
             ..| |.||.|.    ||| |. .  . .                                                           
KPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPLTTKDL

--------------LGWDKRVEIITGIAEGLAYLHHD----YGPKVVHRDVKCDNILLDAEMK-----------PRLGDFGLAK-----LLRENKPSTAS
              |    .. .   ||.|..|||        ...||||. . |.|.. ...            ...||||..     | |.  ...  
LQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDY

KLAGTHG----------------------------YIAPEYAY---------TLKVDERADVYSFGIVVLEVLTGKMATWRD-ATN--------DLDLVE
  ....|                            . |||            . |  .  ||.|||... |..|   ...    .|        . ...|
YRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVME

WVKLM-------PVE--ELALEMGAEEQCY--------------KLVLEIALACAEKSPSLRPTMQIVVDRL
 ..         . .  .  ..| . ..|               ... .. . | .. |. |||.. ....|
YLRRGGRLCRSGL-NEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_d-2.AA Pkinase 717-902 26 8.2e-38 134.78 Pfam 15-209 (293) Show / Hide 
Range on Protein: 717-902
Range on HMM: 15-209/293
Sequence Identity: 26% (52 aa)

VYKGVLKGG-IRVAVKEVQSEDHSHVAEFEA----EVATLGNIRHRNVVKFLASCTNKRSHLLVYEFMPLG----NLRDLLHGKMARSFSLGWDKRVEII
|||.. ||  ..||||..  .. ..  . ..    |.. . ...| |.|... ....|..  .| |... |     | |...... ..|.. ..    ..
VYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYM

TGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKP----RLGDFGLAKLLRENKPSTASKLAGTHGYIAPEYAY-TLKVDERADVYSFGIVVLEVLTGK
. |..||.|.|     ...|||.| .|||.| .. .    ...||||||.... . | .. ..|| .|.|||      . . ..|..|.|... |.|.|.
YQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase LRR8_d-2.AA TKL-Unique 716-966 28 5.3e-35 120.93 In-house 12-290 (290) Show / Hide 
Range on Protein: 716-966
Range on HMM: 12-290/290
Sequence Identity: 28% (81 aa)

NVYKGVLKGGIRVAVKEVQ-SEDHS--HVAEFEAEVATLGNIR-HRNVVKFLASCT----NKRSHLLVYEFMPLGNLRDLLH------GKMARSFSLGWD
.||||. . |. ||.|     || |   . ||| || .. ... | |.|.. . |.          .| |..|.|.|.|.||         ...  | . 
QVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQ

KRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAE-----MKPRLGDFGLAKLLRENKPSTASKL--------AGTHGYIAPEYAYT--LKVDERA
.|| ..  || |. ||||  .| . ||| |  |.|.| .     .. .. ||||.|..  .  .|.. .         |.  ..|||       . .| .
QRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKS

DVYSFGIVVLEVLTGKM-ATWRDATNDLDLVEWVKLMPV--EELALEMGAEEQCYKLVLEIALACAEKSPSLRPTMQIVVDRL
||||||||. | .|.|   |..    ..|  .| ..  .  |.. .. .  . | |   ..  .|    || ||. . .. ||
DVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIP--NHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase LRR8_d-2.AA MLK 717-903 25 1.6e-32 110.14 In-house 15-234 (291) Show / Hide 
Range on Protein: 717-903
Range on HMM: 15-234/291
Sequence Identity: 25% (57 aa)

VYKGVLKGGI----RVAVKEVQSEDHSHVAE-------FEAEVATLGNIRHRN----VVKFLASCTNKRSH-LLVYEFMPLGNLRDLLHGKMA-------
|.||. .. .     ||||.| ..    ...       || |.  |  ..|.|    ...|.. |..  .| ..| |... | | ..|||.         
VWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLHGARSKWMDANH

---RSFSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDA------EMKPRLGDFGLAKLLRENKPSTASKLAGTHGYIAPEY---AYTLK
   ...    |  . . . .|.|..||| .  ....||| |  |||.|.      ... .  |||... . ... ..  . |||  . |||    .   |
NQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEK

VDERADVYSFGIVVLEVLTGKM
..| .||.|.|.|  |.||...
YSEKCDVWSWGVVLWEMLTREV
Kinase LRR8_d-2.AA LISK 717-915 25 7.1e-31 97.4 In-house 10-253 (296) Show / Hide 
Range on Protein: 717-915
Range on HMM: 10-253/296
Sequence Identity: 25% (64 aa)

VYKGVLK-GGIRVAVKEVQS-----EDHSHVAEFEAEVATLGNIRHRNVVKFLASCTN-KRSHLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITG
|||| ..  |  .|.|. ..     .| .    .. ||... |.||.|.|.|   | . ...  .| |..  |.|...|. .  ... | |..|| | ..
VYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPWPQRVKIALD

IAEGLAYLHHDYGPKVVHRDVKCDNILLDAE----MKPRLGDFGLAKLLRENK-----------------------------PSTASK----LAGTHGYI
||.|..|||     ...||| |  |.|..       . ...|||.|... . .                             ..   |      ||    
IACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTICGTPYWM

APEYAYTLKVDERADVYSFGIVVLEVLTGKMATW----RDATNDLDL
|||     . ||..||.|||||..|  |.. |.     |.. .|..|
APEMLLGQSYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGL
Kinase LRR8_d-2.AA STE 717-902 20 2.7e-30 104.23 In-house 15-265 (359) Show / Hide 
Range on Protein: 717-902
Range on HMM: 15-265/359
Sequence Identity: 20% (53 aa)

VYKGVLKG----------------GIRVAVKEVQSED-----------------HSHVAEFEAEVATLGNIR--HRNVVKFLASCTNKR-------SHLL
|||.. .                 | ..|.|..  |.                 |. . ... |. .. . .  | |.||.. .. ..        .  .
VYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWI

VYEFMPLGNLRDLLHGKMARSFSLG----------WDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRENKP-----
. |.|. | |.|... |. . ..|            .    |.  | .|| |..|. .  ..|||.|..||||       | |||... | .. .     
CMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH--IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSN

-------STASK---LAGTHGYIAPEYAYT------LKVDERADVYSFGIVVLEVLTGK
       ....|   ..||  . |||           . |...|..|.|....| .|||
NIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase LRR8_d-2.AA Dicty4 717-902 33 2.7e-30 98.36 In-house 15-214 (277) Show / Hide 
Range on Protein: 717-902
Range on HMM: 15-214/277
Sequence Identity: 33% (67 aa)

VYKGVLKGGIRVAVKEV--QSED--HSHVAEFEAEVATLGNIRHRNVVKFLASCT----NKRSHLLVYEFMPLGNLRDLLHG---KMARSFSLGWDKRVE
||||  . |. ||||      ..   .   || .||. ...||| |...|. .||    .. . . | |.|| |||  |||        | .| |  .  
VYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKR

---IITGIAEGLAYLHH-DYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRENKPSTA--SKLAGTHGYIAPEYAYTLKVDERADVYSFGIVVLEVL
   .   .| |...||  .  | ..||| | .|.| |. ..   .||||... .. .  ..  .  .|| .. |||       .| |||||||||  | |
AMRMAFDAARGMNWLHCCN--PVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEIL

TGK
|..
TRQ
Kinase LRR8_d-2.AA RIPK 725-902 28 9.9e-30 98.48 In-house 18-225 (290) Show / Hide 
Range on Protein: 725-902
Range on HMM: 18-225/290
Sequence Identity: 28% (59 aa)

GIRVAVKEVQSED------HSHVAEFEAEVATLGNIRHRNVVKFLASCTNKRS------HLLVYEFMPLGNLRDLLHGKMA-RSFSLGWDKRVEIITGIA
| .||.| . .         . . .   |.. . ..|....|. .  |  .          .| |.|. |.| ..|| |.    . . |. |  .|  |.
GDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEIS

EGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLREN--KP---------STASKLA-GTHGYIAPEYAY--TLKV----DERADVYSFGI
.|  || |. .| . ||| |  |||.|...   . |||||. ..    .          |..||.  ||. |..||       |     ..  |||||.|
CGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFAI

VVLEVLTGK
|. ||||.|
VMWEVLTQK
Kinase LRR8_d-2.AA DRK 725-900 31 1.6e-28 93.73 In-house 22-197 (258) Show / Hide 
Range on Protein: 725-900
Range on HMM: 22-197/258
Sequence Identity: 31% (57 aa)

GIRVAVKEVQS--ED-HSHVAEFEAEVATLGNIRHRNVVKFLASCTNKRSHLLVYEFMPLGNLRDLLHGKMARSFSLGWDKRVEIITGIAEGLAYLHHDY
|. ||||      ..    . ||  |.  . . || |.. |. .|.|  . . . |.||.| |   ||     | .. |  .  .   .| |. |||   
GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH---DESIEMDWPLMKQMMFDCAKGMIYLHC-C

GPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRENKPSTASKLA-GTHGYIAPEYAYTLKVDERADVYSFGIVVLEVLT
 | ..||| | .| | |   .    ||||.   .  |  .. . . || . .|||        | ||||||.||  |..|
NPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase LRR8_d-2.AA Pkinase_Tyr 716-854 27 4e-28 95.86 Pfam 14-161 (270) Show / Hide 
Range on Protein: 716-854
Range on HMM: 14-161/270
Sequence Identity: 27% (42 aa)

NVYKGVLK-----GGIRVAVKEVQSEDHSHV----AEFEAEVATLGNI-RHRNVVKFLASCT-NKRS--HLLVYEFMPLGNLRDLLHGK--MARSFSLGW
.||||..|     ..| |||| .  |...|     ..| .|.... .. .| |.|.... ||  ...  ...| |.||.|.|.| |. .    ..... .
EVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

DKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLL
   ... . ||.|..||.     . .|||. . |.|.. ... . .|||||...
--LLQMCWQIAKGMEYLESK---NCIHRDLAARNCLVTENNVVKICDFGLARDI
Kinase LRR8_d-2.AA TyrKc 710-966 23 6.2e-24 86.76 SMART 1-280 (280) Show / Hide 
Range on Protein: 710-966
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

ICRGRN-------NVYKGVLKGGIRVAVKEVQSEDHSHVAEFEAEVATLGNI--RHRNVVKFLASCTNK-------RSHLLVYEFMPLGNLRDLLHGKMA
|  |.         ||||..|  | |||| ....    ...|  |   . ..  .| |.|.... || .         ...| |.||.|.|.| |. .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

RSFSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLREN------KPSTASKL-AGTHG-----YIAPEYAYTLK
.   | ... ... . ||.| .|||.    ...|||  . |.|....   . .||||.. . .       |    .|   |...       |||   . |
K---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK

VDERADVYSFGIVVLEVLTGKMATWRDA----TNDLDLVEWVK---LMPVEELALEMGAEEQ----CYKLVLEIALACAEKSPSLRPTMQIVVDRL
  .  ||.|||..  |..|  .  . .      .. ...|.||    ||  . ..    .      | . . .| . | .  |. |||.. .....
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
S_TKc LRR8_d-2.AA S_TKc 704-967 21 2.3e-22 81.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 704-967
Range on HMM: 1-231/231
Sequence Identity: 21% (59 aa)

ESKDNLICRGRN-NVYKGVLKG-GIRVAVKEVQSEDHSHVAEFEAEVATLGNIRHRNVVKFLASCTNKRSHLLVYEFMPL--GNLRDLLHGKMA----RS
  . ..| .|    |||.. |. | .||.|..          .. |.. | . .| |.||.. .. .  .  .| |...   |.|.|... .      . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

FSLGWDKRVEIITGIAEGLAYLHHDYGPKVVHRDVKCDNILLDAEMKPRLGDFGLAKLLRENKPSTASKLAGTHGYIAPEYAYTLKVDE-RADVYSFGIV
|.  .     ..  |...|.|.|     ...|||.| .|||||      ..|||||..|        . . ||  |.|||     . .  ..|..|.|..
FPE-H--ARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

VLEVLTGKMATWRDATNDLDLVEWVKLMPVEELALEMGAEEQCYKLVLEIALACAEKSPSLRPTMQIVV-------DRLN
. | |.|.   .    ..  . . ..                  . ....   | .| |. ||| ..         .   
LYEMLCGYPPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTAEALQDEWDIKCHPWF
Kinase LRR8_d-2.AA DRK 948-968 38 0.00198 7.52 In-house 238-258 (258) Show / Hide 
Range on Protein: 948-968
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CAEKSPSLRPTMQIVVDRLNG
| .  |. ||.|| .. ||  
CWNEDPQHRPSMQECLERLEA
Kinase LRR8_d-2.AA Dicty4 948-968 26 0.025698 3.73 In-house 255-277 (277) Show / Hide 
Range on Protein: 948-968
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CAEKSPSLRPTMQIVVDR--LNG
| ...|. ||... .. |  |. 
CWDHDPQHRPSFEEIIQRRILEH
Kinase LRR8_d-2.AA Pkinase_Tyr 943-966 25 2.510131 1.73 Pfam 247-270 (270) Show / Hide 
Range on Protein: 943-966
Range on HMM: 247-270/270
Sequence Identity: 25% (6 aa)

EIALACAEKSPSLRPTMQIVVDRL
.. . | .. |. |||.. .. .|
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR8_d-2.AA Pkinase_Tyr 887-903 44 3.698087 1.16 Pfam 196-213 (270) Show / Hide 
Range on Protein: 887-903
Range on HMM: 196-213/270
Sequence Identity: 44% (8 aa)

DVYSFGIVVLEVLT-GKM
||.|||..  |..| |..
DVWSFGVLMWEIFTYGEQ