Gene LRR8_j-2 (S.moellendorffii)

LRR8_j-2

Species: S.moellendorffii
Alias: LRR8_j-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR8

Sequence

Name Sequence Type Origin Length Description Download
LRR8_j-2.AA Protein None 1028 None Fasta, JSON
LRR8_j-2.NA RNA None 3087 None Fasta, JSON
LRR8_j-2.kin_dom Protein Kinase Domain None 216 None Fasta, JSON

Protein domain

Protein domains of LRR8_j-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR8_j-2.AA LRRNT_2 23-63 36 2.3e-12 43.07 Pfam 1-46 (46) Show / Hide 
Range on Protein: 23-63
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

GSEEVAALLGVKELLV--DE-FGHTNDWSASD--SSPCSWTGIQCD
 .....|||  |  |.  |  .|   .|..|.  |..|||||. ||
HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 LRR8_j-2.AA LRR_1 92-114 33 0.335006 8.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 92-114
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

HLVNISLEQ-N--NLAGPLPPE-LSLL
.|  ..|   |  || | .||. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 116-138 25 0.031924 12.05 Pfam 1-26 (26) Show / Hide 
Range on Protein: 116-138
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RLRFLNISH-N--NF-GYGFPAN-LSAI
.|. |..|. |  |. |. .| . . . 
NLQHLDLSGCNCCNLTGH-IPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 140-162 33 0.007551 14.27 Pfam 1-26 (26) Show / Hide 
Range on Protein: 140-162
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

TLEVLDTYN-N--NFSGPLPPE-LGAL
.|..||  . |  |..| .||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 164-186 37 0.006378 14.53 Pfam 1-26 (26) Show / Hide 
Range on Protein: 164-186
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SIRHLHLGG-S--YFSGAIPPE-LGNL
...||.|.|     ..| |||. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 188-210 51 5.2e-05 21.93 Pfam 1-26 (26) Show / Hide 
Range on Protein: 188-210
Range on HMM: 1-26/26
Sequence Identity: 51% (14 aa)

TLRYLALSG-N--SLTGRIPPE-LGNL
.|..| ||| |  .||| |||. . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 212-235 29 1.003843 6.74 Pfam 1-26 (26) Show / Hide 
Range on Protein: 212-235
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

ELEELYLGYYN--EFEGGIPRE-IGKL
 |..|.|.. |   ..| || . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 237-259 44 0.001141 17.18 Pfam 1-26 (26) Show / Hide 
Range on Protein: 237-259
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLVRIDLGFC---GLTGRIPAE-IGNL
|| ..||. |    ||| || . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 261-283 33 3.188842 4.96 Pfam 1-26 (26) Show / Hide 
Range on Protein: 261-283
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

RLDSIFLQI-N--NLSGPIPAE-IGLL
.| .. |.  |  ||.| || . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 285-307 40 0.001194 17.11 Pfam 1-26 (26) Show / Hide 
Range on Protein: 285-307
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

ALKSLDLSN-N--LLSGPIPDE-LAML
 |..||||. |   |.| ||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 309-331 29 0.423235 8.07 Pfam 1-26 (26) Show / Hide 
Range on Protein: 309-331
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

SIALVNLFR-N--RLSGSIPSF-FGDL
..   .| . |  .|.|.||.  |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 333-355 44 0.00765 14.25 Pfam 1-26 (26) Show / Hide 
Range on Protein: 333-355
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLEVLQLWA-N--NLTGSIPPQ-LGQA
||..| |   |  ||||.|||  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 382-404 33 0.036827 11.83 Pfam 1-26 (26) Show / Hide 
Range on Protein: 382-404
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

ALQVLILYG-N--QIGGALPES-LGQC
 ||.| | | |  .. | .|.| . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 358-381 33 0.084012 10.56 Pfam 1-26 (26) Show / Hide 
Range on Protein: 358-381
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SLMTVDLSS-N--SLSGSIPDKICWGG
.| . |||. |  .|.|.||. .. . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 406-428 29 0.335006 8.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 406-428
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

TLVRVRLGH-N--QLTGGLPKN-TLGL
.| .  |.. |  .||| .|..   .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 454-476 44 0.003794 15.33 Pfam 1-26 (26) Show / Hide 
Range on Protein: 454-476
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

ELELLDLSQ-N--RLRGSIPRA-IGNL
 |. ||||  |  .| |.||   . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 478-500 37 0.015527 13.16 Pfam 1-26 (26) Show / Hide 
Range on Protein: 478-500
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

NLKNLLLGD-N--RISGRIPAS-IGML
||. | |.. |  ...| || | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 502-524 37 0.003122 15.63 Pfam 1-26 (26) Show / Hide 
Range on Protein: 502-524
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLSVLDASG-N--AISGEIPRS-IGSC
.| .|| || |   ..|.|| | . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 526-548 37 0.007123 14.36 Pfam 1-26 (26) Show / Hide 
Range on Protein: 526-548
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RLSSVDLSR-N--QLVGAIPGE-LAQL
.| . |||. |  .|.| || . . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 550-572 29 0.337189 8.42 Pfam 1-26 (26) Show / Hide 
Range on Protein: 550-572
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

ALDALNVSR-N--GLSGEIPRE-LEEA
 |  |..|. |   |.|.|| . .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR8_j-2.AA LRR_1 574-598 32 26.120429 1.72 Pfam 1-26 (26) Show / Hide 
Range on Protein: 574-598
Range on HMM: 1-26/26
Sequence Identity: 32% (9 aa)

ALTSADFSY-N--RLFGPIPSQGQFGFF
 |.. |.|. |  .| | ||.   |  .
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
Kinase LRR8_j-2.AA TKL 714-940 25 2.6e-62 213.35 In-house 1-312 (364) Show / Hide 
Range on Protein: 714-940
Range on HMM: 1-312/364
Sequence Identity: 25% (82 aa)

IGRGGSGTVYKAMMRS---------GELVAVKRLASCPVNSGKRSS---------------GSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHET-
||.||.|.|||.  |          |. ||||.. |  ...  ..|                  .|.  | .  |.  . ..|| |||...|.| . .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------NLLVYEYMPNGSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCS-----PLIVHRDVKSNNILLDSNLR-----------
              .|.||.|.||| ..||           |. | . | ..| |..||| .       | |.||| ||.|||.|.|..           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AHVADFGLAKLFQGSDKSESMSS-----------------VAGSYGYIAPEYA-----YT-----------LKVNEKSDIYSFGVVLLELVTGRRPI
   . ..||||.. ...| ... ...                 . |.... |||       ||           .. .||.|.||||.|| |..|..|| 
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPY

E-PGYGDEI------DIVKWVRK
. ..| ..|      .. ..| .
YDYPYMPMIFQDPFEEMFMMVCD
Kinase LRR8_j-2.AA IRAK 709-923 33 1.4e-56 194.32 In-house 2-223 (317) Show / Hide 
Range on Protein: 709-923
Range on HMM: 2-223/317
Sequence Identity: 33% (77 aa)

SEDNVIGRGGSGTVYKAMMRSGE-LVAVKRLASCPVNSGKRSSGSRSSHDDFGFS--AEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNGSLGEVL
..||.|| || |.||.. ..  .  .|||.|        .  . |  .|. .. .   |.... ..|| ||| |.|.|.  .   |||.|||||||   |
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLK-------EMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRL

HGVGTKACP-VLDWETRYKVAVQAANGLCYLHHDCS--PLIVHRDVKSNNILLDSNLRAHVADFGLAKL--FQGSDKSESM-----SSVAGSYGYIAPEY
.. ..   |  | | .| ...  .|.|. .|| . .  |.| |.|.|| ||||| .. .  .||||.    . .. .. .      | | |.  | .||.
WCQDGQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPII-HGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEF

AY--TLKVNEKSDIYSFGVVLLELVTGRRP
 .  . .   |.|.||||.||||..||.|.
IRDPQGQLTKKTDVYSFGIVLLEVLTGCRA
Kinase LRR8_j-2.AA MLK 708-923 30 2.4e-45 155.25 In-house 1-235 (291) Show / Hide 
Range on Protein: 708-923
Range on HMM: 1-235/291
Sequence Identity: 30% (73 aa)

LSEDNVIGRGGSGTVYKAMMRSGE----LVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMN----IVKLLGFCSNHETN-LLVYEYMPN
. .  .|| |..| |.|. .|  .     ||||| .. .  ... .. ..       |  |.  | ...| |    |....| |.... . ..| ||...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWD------FEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEG

GSLGEVLHGVGTKACP---------VLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDS------NLRAHVADFGLAKLFQGSDKSESMSS
||| .||||  .|  .         | | .   . |.| |.|. ||| .  ..|.||| || |||.|       .. . ..|||... .. ..  . | |
GSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMS

VAGSYGYIAPEY---AYTLKVNEKSDIYSFGVVLLELVTGRRP
 ||.| . |||    .   |..||.|..|.|||| |..|.. |
NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Pkinase LRR8_j-2.AA Pkinase 708-921 26 1.1e-43 155.48 Pfam 1-209 (293) Show / Hide 
Range on Protein: 708-921
Range on HMM: 1-209/293
Sequence Identity: 26% (61 aa)

LSEDNVIGRGGSGTVYKAMMRSGEL-VAVKRLASCPVNSGK------RSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNG-
.    .||.|..|.|||.. .. .  ||||..  .  .|.|      .              .|.| . ...| |||.|.... ..    .| ||...| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGL

---SLGEVLHGVGTKACPVL--DWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRA----HVADFGLAKLFQGSDKSESMSSVAGSYGY
   .| .....   ..  ..  ....  ... | . || |.|      |.|||.|. |||.|.|       ...||||||.|.   ... |....|...|
YVMDLFDYIST---WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWY

IAPEYAY-TLKVNEKSDIYSFGVVLLELVTGR
.|||      .   |.|..|.|..| |...||
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase LRR8_j-2.AA TKL-Unique 712-923 33 5.8e-42 145.74 In-house 3-233 (290) Show / Hide 
Range on Protein: 712-923
Range on HMM: 3-233/290
Sequence Identity: 33% (80 aa)

NVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIR-HMNIVKLLGFCS----NHETNLLVYEYMPNGSLGEVLH
|.||.||.|.|||.. | |. ||.|...       . .. | .. ..  |. || .. |.. | |||.. |.|           .| ||.| ||| .|||
NKIGEGGYGQVYKGKWR-GYPVAIKQFH-------PNEDSSNEMMQE--FENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLH

-----GVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSN-----LRAHVADFGLAKLFQGSDKSESM-------SSVAGSYG
         .    |... |.| | ..| |..||||   | | ||| || |.|.|.|     ... ..||||.|.   ..|. .        ... ||. 
QNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFR

YIAPEYAYT--LKVNEKSDIYSFGVVLLELVTGRR------P
..|||       . .||||.||||.|| |..|. .      |
WMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR8_j-2.AA LRRK 708-923 28 6.4e-41 142.27 In-house 1-282 (351) Show / Hide 
Range on Protein: 708-923
Range on HMM: 1-282/351
Sequence Identity: 28% (82 aa)

LSEDNVIGRGGSG-TVYKAMMRS---------------------------GELVAVKRLASCP------VNSGKRSSG------------------SRSS
| . . |||||.| .||.| .|.                           .. ||.| .  .|       |    |..                  ....
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCN---NSNNNNNLNNNNSEQVEDMDQNHEDC

HDDFG-FSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPNGSLGEVLH---GVG---TKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDV
.  |  |  ||  . . .| |||.|.||| .. .  .| ||.|.|.| ..||     |    |  ....| ...|.|.| | |. || |...| |.||| 
CRAFREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMK--AHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDL

KSNNILL---D---------SNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAY---TLKVNEKSDIYSFGVVLLELVTGR-RP
|| ||||   .          .  |..||||.  .|  .....  . . |  |. |||      .   .||.|.||||..| ||.|.. .|
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase LRR8_j-2.AA S_TKc 708-988 22 3.2e-39 137.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 708-988
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

LSEDNVIGRGGSGTVYKAMMRS-GELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHETNLLVYEYMPN--GSLGEV
    ..||.|. |.|||.  .. |..||.|..                      .  |.| | | .| |||||.... . .   .| ||...  |.| ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

LHGVGT--KACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAYTLKVN
..  |.  . .|    ..|. .. | ...| |.|      |.|||.|  |||||.  .  ..|||||...         ... |.  |.|||     . .
IKKRGRHGLRFPFPE-HARF-YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYG

E-KSDIYSFGVVLLELVTGRRPIEPGYGDEIDIVKWVRKMIQTKDGVLAILDPRMGSTDLLPLHEVMLVLRVALLCSSDQPAE-------RPAM
  |.|..|.|..| |...|. | .    ..  . | ..                  | ... . . .|.   .   .  .  .        | .
KCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR8_j-2.AA RIPK 714-926 31 2.2e-38 128.42 In-house 1-230 (290) Show / Hide 
Range on Protein: 714-926
Range on HMM: 1-230/290
Sequence Identity: 31% (74 aa)

IGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNHET------NLLVYEYMPNGSLGEVLHG
.|.||.|.|.||  |.   ...|  . |.    .    . . .     . |.. . |.|. .||...|||   |         .| |||.|||| ..|| 
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHM-DDQERMY----QKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHT

VGT-KACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGS----DKS-----ESMSSVA--GSYGYIAPEY
       |.. |  |    .. . | ||| |.  | | ||| |  |||.|.|. . .||||||.  ..|    |.       || |    |   |..|| 
KWPYQHHPDP-WPLRCRMIHEISCGMCYL-HSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEH

AY--TLKV----NEKSDIYSFGVVLLELVTGRRPIEP
      |     ..|.|.|||..|. |. |.. | |.
FRTDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYED
Kinase LRR8_j-2.AA Dicty4 761-923 37 1.9e-37 122.6 In-house 45-216 (277) Show / Hide 
Range on Protein: 761-923
Range on HMM: 45-216/277
Sequence Identity: 37% (66 aa)

FSAEVQTLGKIRHMNIVKLLGFCS----NHETNLLVYEYMPNGSLGEVLHG------VGTKACPVLDWETRYK---VAVQAANGLCYLHHDCSPLIVHRD
| .||  ..|||| ||....| |     . .. . | |||| |.| ..||         .|    |||... .    |  || |. .||  | | |.|||
FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIK----LDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRD

VKSNNILLDSNLRAHVADFGLAKLFQ-GSDKSESMSSVAGSYGYIAPEYAYTLKVNEKSDIYSFGVVLLELVTGRRP
 || |.| | |.|. |.||||..... ..|..  .....|. .. |||       |||.| |||| || |..|.  |
LKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEP
Kinase LRR8_j-2.AA TK 708-995 15 3.7e-36 118.16 In-house 1-486 (486) Show / Hide 
Range on Protein: 708-995
Range on HMM: 1-486/486
Sequence Identity: 15% (79 aa)

LSEDNVIGRGGSG---TVYKAMMRSG--------------------------ELVAVKRLASCPVNSGK-RSS-------GSRSSHDDFG-----FSAEV
.   ...|.|  |   .|||...|..                          . |||| | .   .| . .         |        |     . .| 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDG--------GEDFLEEAEEM

QTLG--KIRHMNIVKLLGFCSNHET------------NLLVYEYMPNGS----LGEVLH--GVGTKACPV------------------------------
. .   . .| |||.|.| |. .|.             ..| ||||.|.    | . |.    ...  .                               
KMMCHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNS

---------------------------------------LDWETRYKVAVQAANGLCYLHHD-CSPL---IVHRDVKSNNILLDSNLR-----------A
                                       |. ...   ..|.|.|. |||   |. .   .||||.   |.|...|..           .
PCPEEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVC

HVADFGLAK-----LFQGSDKSESMSSVAGSYG---------------------------YIAPEYAY---------TLKVNEKSDIYSFGVVLLELVT-
 .|||||..     |    ....   .. . ..                           . |||            . |  .|||..||||.. |..| 
KIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTY

GRRPIEPGYGDEIDIV----KWVRKMIQT----------KDGVLAILDPRMGSTD------LLPLHEVMLVL-RVALLCSSDQPAERPAMRDVVQML
|. |  .|  ..  ..    . | .....          . |    . . .. .|      . | |.   .. .. . | . .|..|| .......|
GQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMH-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR8_j-2.AA STE 708-923 22 1.1e-34 119.91 In-house 1-267 (359) Show / Hide 
Range on Protein: 708-923
Range on HMM: 1-267/359
Sequence Identity: 22% (62 aa)

LSEDNVIGRGGSGTVYKAMMR----------------SGELVAVKRLASCPVNSGKRS---SGSRS-----SHDDFGFSAEVQTLGKIR--HMNIVKLLG
.    .||.|..||||||| .                .||..|.|..  .. |. . .   . . .     . .   .  |.... | .  | |||| .|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQEN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYG

FCSNH-------ETNLLVYEYMPNGSLGEVLHGVGTKACP---------VLDWETRYKVAVQAANG-LCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVA
 . .        ..  .. |||..||| .... .. . .|         ... .   ....|   | | |||      |.|||.|. ||||     .  .
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLC

DFGLAKLFQGS--------------DKSESMSSVAGSYGYIAPEYAYT------LKVNEKSDIYSFGVVLLELVTGRRP
|||... .. |              . ..   ...|.  . |||           . ..|.||.|.| ...|..||. |
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR8_j-2.AA Pkinase_Tyr 708-923 27 9.2e-32 108.19 Pfam 1-214 (270) Show / Hide 
Range on Protein: 708-923
Range on HMM: 1-214/270
Sequence Identity: 27% (64 aa)

LSEDNVIGRGGSGTVYKAMMR-----SGELVAVKRLASCPVNSGKRSSGSRSS---HDDFGFSAEVQTLGKI-RHMNIVKLLGFCS-NHET--NLLVYEY
.. . ..|.|  |.|||. ..      .  |||| |            |. ..   ..|| .. |.... .. .| |||.|.| |.   |    ..| ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK----------EGAMHEQNCREDF-MR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEY

MPNGSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKS-ESMSSVAGSYGYIAPE
||.|.| . |.       . |. ..  . ..| |.|. ||.      ..|||.   |.|...|. . ..|||||.. .  |    . ..        |||
MPHGDLLDYLRKHR-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPE

YAYTLKVNEKSDIYSFGVVLLELVT-GRRP
   . | ..|||..||||.. |..| |. |
CINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR8_j-2.AA Dicty4-Unclassified 708-923 32 1.6e-29 98.22 In-house 1-207 (263) Show / Hide 
Range on Protein: 708-923
Range on HMM: 1-207/263
Sequence Identity: 32% (73 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKIRHMNIVKLLGFCSNH----ETNLLVYEYMPNGSLGE
.  |  ||.|    |.|   . |  |||| .     |..| .       |   | .||  || | | | ||. | | |      |   | | |. | | |
IQIDQFIGKGHFSKVHKGNWK-GKDVAVKKF-----NENKFKFREEMIQD---FKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFE

VLHGVGTKACPVLDWET--RYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKSESMSSVAGSYGYIAPEYAYTLKV
| |         .  .     |.|   | |. .||   .  ..|||.|| |||.| .  . .||||..      |    |  .||     .||       
VIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESY

NEKSDIYSFGVVLLELVTGRRP
| |||.||....| ||.||  |
NQKSDVYSYAMMLYELATGDEP
Kinase LRR8_j-2.AA TyrKc 708-995 22 1.1e-24 89.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 708-995
Range on HMM: 1-280/280
Sequence Identity: 22% (71 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVKRLASCPVNSGKRSSGSRSSHDDFGFSAEVQTLGKI--RHMNIVKLLGFCSNH-------ETNLLVYEYMPN
.. . ..|.|  |.|||....  . |||| | ..                   |  | . . |.  .| |||.|.| |. .       |  ..| ||||.
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

GSLGEVLHGVGTKACPVLDWETRYKVAVQAANGLCYLHHDCSPLIVHRDVKSNNILLDSNLRAHVADFGLAKLFQGSDKS----ESMSS----VA---GS
|.| . |.  . |    | ...  . ..|.|.|  |||.     ..|||    |.|...|... ..||||..     |..    .  ..     .     
GDLKDYLRKHRPK----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

YGYIAPEYAYTLKVNEKSDIYSFGVVLLELVTGRRPIEPGYG------DEIDIVKWVRKMIQTKDGVLAILDPRMGSTDLLPLHEVMLVLRVALLCSSDQ
.   |||   . | ..|||..||||.. |. |  .  .| .|      . ......|..    .    .   | | .      .    . .. . |   .
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFT--YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MSF-----VCCPDEMYQIMKQCWHED

PAERPAMRDVVQML
|..|| ...... .
PEDRPTFSEIHECF
Kinase LRR8_j-2.AA Dicty4 708-736 44 0.00297 6.9 In-house 1-28 (277) Show / Hide 
Range on Protein: 708-736
Range on HMM: 1-28/277
Sequence Identity: 44% (13 aa)

LSEDNVIGRGGSGTVYKAMMRSGELVAVK
.  .. ||.|. |.|||.  | |  ||||
INIEQRIGKGSFGEVYKGTWR-GKEVAVK
Kinase LRR8_j-2.AA Dicty4-Unclassified 977-995 36 0.008429 5.38 In-house 245-263 (263) Show / Hide 
Range on Protein: 977-995
Range on HMM: 245-263/263
Sequence Identity: 36% (7 aa)

CSSDQPAERPAMRDVVQML
| .. |  || | ...| |
CWHNDPNKRPTMNQIIQYL
Kinase LRR8_j-2.AA MLK 979-995 41 0.07822 2.3 In-house 275-291 (291) Show / Hide 
Range on Protein: 979-995
Range on HMM: 275-291/291
Sequence Identity: 41% (7 aa)

SDQPAERPAMRDVVQML
.. |..|| .| .|| |
NQDPHKRPSFRQIVQHL
Kinase LRR8_j-2.AA TKL 977-995 26 0.31275 0.2 In-house 346-364 (364) Show / Hide 
Range on Protein: 977-995
Range on HMM: 346-364/364
Sequence Identity: 26% (5 aa)

CSSDQPAERPAMRDVVQML
| .  | .|| . .... |
CWDHDPEKRPSFQEILKRL
Kinase LRR8_j-2.AA Pkinase_Tyr 981-995 26 0.713649 3.58 Pfam 256-270 (270) Show / Hide 
Range on Protein: 981-995
Range on HMM: 256-270/270
Sequence Identity: 26% (4 aa)

QPAERPAMRDVVQML
.|..|| .......|
DPEDRPTFSEIHEQL