Gene LysM_d-2 (S.moellendorffii)

LysM_d-2

Species: S.moellendorffii
Alias: LysM_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LysM

Sequence

Name Sequence Type Origin Length Description Download
LysM_d-2.AA Protein None 431 None Fasta, JSON
LysM_d-2.NA RNA None 1296 None Fasta, JSON
LysM_d-2.kin_dom Protein Kinase Domain None 161 None Fasta, JSON

Protein domain

Protein domains of LysM_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LysM_d-2.AA TKL 136-403 19 6e-40 139.03 In-house 7-364 (364) Show / Hide 
Range on Protein: 136-403
Range on HMM: 7-364/364
Sequence Identity: 19% (75 aa)

GSVFRALVRG----------ADVAIVQKKGS------------------------------FVGNYIELLKIITSVHHVNLVKVLGACLRESE-------
| |...  ||           |||. . |                                |    .| .... . .| |.|. .|.|....        
GEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHP

-----HVYVCYEYEEGVNLREALHSPRAEGFSALASWTSRLQVALDVALGLEYLHDHTM-----PPFVHKHVKSTNIIVTNELR--------------AK
     . .  .|| .| .|.. ||            |  |.. |||.|.|..||| ..      || .|   || || | . ..              .|
VGPWGQLCIVMEYCPGGSLLHYLH------------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IVKFGIPQLPRRK-----------------LVRKNSIKITGTPGYMSPEY----------------QTSGVVSSKMDVFAFGVVLLELLTGKQPGVQLDP
|  ||. .   ..                 . ||..... |||..|.||                 . ..  | |.||..||.|| |.||...|  ....
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

ATKKLKVVSLTDEVTEIM--EERDPRK-----KLRLWIDARLRDSYPVDTAMSVAALARLCIDSNPESRPPMKNVTAKL
 . ..  . . ..   .    .| |..     ..      .   . . |.  |.. |.  | |..||.|| .. .. .|
MPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHH------K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LysM_d-2.AA TKL-Unique 136-325 25 5.8e-24 81.5 In-house 11-233 (290) Show / Hide 
Range on Protein: 136-325
Range on HMM: 11-233/290
Sequence Identity: 25% (58 aa)

GSVFRALVRGADVAIVQKK------GSFVGNYIELLKIITSVH-HVNLVKVLGACLR---ESEHVYVCYEYEEGVNLREALH-SPRAE---GFSALASWT
|.|...  || .|||.|..       ... . .. ....   | | |.|.  |.|        . .   || .| .|.. || .         .   .. 
GQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQ

SRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNE-----LRAKIVKFGIPQLPRRKLVRKNSIK-------ITGTPGYMSPEYQTS--GVVSSKM
 |.. |.|.|.|..||| |. ||  |   ||.|. |.|.     ...||..||.. .  . .  .|. .         |.. .|.||  ..     | | 
QRVKMAIDIAQGMYYLH-HCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKS

DVFAFGVVLLELLTGKQ------P
||..||.|| |..|.|.      |
DVYSFGIVLWEIATRKITKTYKKP
Kinase LysM_d-2.AA TK 136-403 12 1.4e-19 61.59 In-house 13-486 (486) Show / Hide 
Range on Protein: 136-403
Range on HMM: 13-486/486
Sequence Identity: 12% (60 aa)

G---SVFRALVRGA---------------------------DVAIVQKKG--SFVGN-YIE--------------LLKIITSVH-----HVNLVKVLGAC
|    |.....||                            .||. ..|   .   .  ..              .. ..   .     | |.|. .|.|
GSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNIVRLYGVC

LRES-----------EHVYVCYEYEEGVN----LREALHSPRAEGFSALASWT-----------------------------------------------
...            |....  || .. .    ||. |.. | ...  . .                                                 
TQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLIKDHPPPL

-----------------------SRLQVALDVALGLEYLHDHTM---PPFVHKHVKSTNIIVTNELR-----------AKIVKFGIPQLPR----RKLVR
                        .|  ....| |.||||..     . |||  .   |. |.....           .||  ||    ..    |.. .
TTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYS

KNSIKITGTPG----------------------------YMSPEYQTSGV---------VSSKMDVFAFGVVLLELLT-G-KQPGVQLDP-----ATKKL
.     ....|                            .|.||  ...|          ..| ||..|||.. |..| | .... ...      .    
DDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKD----

KVVSLTDEVTEIMEERDPRKKLRLWIDA--------------RLRDSYPVDTA--------------MSVAALARLCIDSNPESRPPMKNVTAKL
                 . . .   . .              |.|   |..                  .. | . | . .|| || .. .  .|
---------------G-DNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LysM_d-2.AA IRAK 219-403 26 3.3e-19 64.85 In-house 107-317 (317) Show / Hide 
Range on Protein: 219-403
Range on HMM: 107-317/317
Sequence Identity: 26% (58 aa)

SWTSRLQVALDVALGLEYLHDHT-MPPFVHKHVKSTNIIVTNELRAKIVKFGIPQLPRRKL-VRKNSI------KITGTPGYMSPEYQT--SGVVSSKMD
||  |. ...  |.|...||.     |. |  .|| ||     . .||  ||    .. .    | ..      .. ||  || ||. .  .|  . | |
SWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTD

VFAFGVVLLELLTGKQPGVQLDPATKKLKVVSLTDEVTEIMEERD--------------------PRKK--LRLWIDARLRDSYPVDTAMSVAALARLCI
|. ||.||||.|||  . .  .| .. ||     | . |||||.                     ||.     . || |  .  | . . . . .|  | 
VYSFGIVLLEVLTGCRAVYDDRPEHYYLK-----DLCEEIMEEWGHLDSCQSTLWVGVATDAWAAPRRMQIYEKFIDHRMPP-CPPNMEKEMCQCACCCG

DSNPESRPPMKNVTAKL
      |..|. |...|
HHRANRRCDMAWVMQQL
Kinase LysM_d-2.AA MLK 128-325 24 7.8e-19 62.07 In-house 1-235 (291) Show / Hide 
Range on Protein: 128-325
Range on HMM: 1-235/291
Sequence Identity: 24% (59 aa)

FSEASKIG----GSVFRALVRGAD-----VAIVQKKGSF---------VGNYIELLKIITSVHHVN----LVKVLGACLRESEHVYVCYEYEEGVNLREA
. .  .||    |.|...  |. |     ||. . . ..           .  .  ..   . | |     ....|.||..  |...  || ||  | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHSPRAEGF--------SALASWTSRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTN------ELRAKIVKFGIPQLPRRKLVRK--NSIKITGT
||. | ...        ..  .  . .. ||..| |..||| .  .| .| . || || ...      .. .||  ||.     |.. ..  |  .  ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGT----SRDWHQMCTNMMSNAGT

PGYMSPEY--Q-TSGVVSSKMDVFAFGVVLLELLTGKQP
. .|.||   |  .. .| | ||. .|||| |.||.. |
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LysM_d-2.AA Dicty5 223-325 29 7.2e-18 58.08 In-house 106-202 (260) Show / Hide 
Range on Protein: 223-325
Range on HMM: 106-202/260
Sequence Identity: 29% (31 aa)

RLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNELRAKIVKFGIPQLPRRKLVRKNSIKI-TGTPGYMSPEYQTSGVVSSKMDVFAFGVVLLELLT
.|  |.|.| ....||       .|  .|| |. .| .. .||. ||.     |    .    .  ||. .|..|  ..     | ||..||.|| |..|
QLHMAIDIAQSMRHLHSMNI---IHRDLKSMNFLITENWKIKIIDFGTS----RFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFT

GKQP
 | |
RKEP
Kinase LysM_d-2.AA LRRK 219-325 33 4.1e-17 57.06 In-house 162-282 (351) Show / Hide 
Range on Protein: 219-325
Range on HMM: 162-282/351
Sequence Identity: 33% (41 aa)

SWTSRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIV---T---------NELRAKIVKFGIPQLPRRKLVRKN-SIKITGTPGYMSPEYQTSG---V
||. .|..||..| |.||||.|. ||..|   || ||..   .         ..  |||. ||| .    . ...    . .|.||.|.||    .   .
SWMLKLKIALQIAKGMEYLHSHN-PPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEE

VSSKMDVFAFGVVLLELLTGK-QP
 . | |...||..| ||||.. .|
YTEKVDCYSFGMILWELLTRQHHP
Kinase LysM_d-2.AA HH498 222-332 28 1.6e-16 48.51 In-house 122-232 (284) Show / Hide 
Range on Protein: 222-332
Range on HMM: 122-232/284
Sequence Identity: 28% (32 aa)

SRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNELRAKIVKFGIPQLPRRKLVRKNSIKITGTPGYMSPEYQT-SGVVSSKMDVFAFGVVLLELL
|.. ...||| | .|||.   .| .|    | || .  . .|..  ||.     . .  .|  |  | . .|.||  . ..  | | ||| .. .. |..
SKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRF-VCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMH

TGKQPGVQLDPA
|.. |   . ||
TREVPFHHYKPA
Kinase LysM_d-2.AA Dicty4 175-325 30 8.4e-15 45.96 In-house 59-216 (277) Show / Hide 
Range on Protein: 175-325
Range on HMM: 59-216/277
Sequence Identity: 30% (48 aa)

NLVKVLGACL---RESEHVYVCYEYEEGVNLREALHS-PRAEGFSALASWTSRLQ---VALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNELRAKIVK
|... .|||.    ... .  . ||    || . ||. |     |   .|. ...    |.|.|.|. .||  . | ..|   || |. |   .|.|.  
NICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCN-PVIIHRDLKSHNLLVDKNWRVKVCD

FGIPQLPRRKLVRKN-SIKITGTPGYMSPEYQTSGVVSSKMDVFAFGVVLLELLTGKQP
||. |. ..    |       |||..|.||   .    .| ||. || || |.||.. |
FGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEP
Kinase LysM_d-2.AA TyrKc 128-403 18 2.7e-14 8.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 128-403
Range on HMM: 1-280/280
Sequence Identity: 18% (59 aa)

FSEASKIG----GSVFRALVRGADVAI-VQKKGSFVGNYIELL---KIITSV--HHVNLVKVLGACLRES------EHVYVCYEYEEGVNLREALHSPRA
 .   |.|    | |...  .  .||. . |...      ...   .| ...  || |.|. .|.|. ..      | ...  || .. .|.. |...| 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

EGFSALASWTSRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNELRAKIVKFGIPQLPRRKLVR------KNSIKIT---GTPG-----YMSPEY
.      ..   |. ....| | ||||..   ...|      |. |......||  ||   | |           |  .. .   |. .      |.|| 
K-----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFG---LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

QTSGVVSSKMDVFAFGVVLLELLT-GKQPGVQL---DPATKKLKVVSLTDEVTEIMEE----RDPRKKLRLWIDARLRDSYPVDTAMSVAALARLCIDSN
   |. ..| ||..|||.. |..| |.||       .   . .     . .  .....                     .  |     .  . . | . .
INYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------F--VCCPDEMYQIMKQCWHED

PESRPPMKNVTAKL
||.|| ....  ..
PEDRPTFSEIHECF
Kinase LysM_d-2.AA S_TKc 128-407 20 2.6e-12 3.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 128-407
Range on HMM: 1-231/231
Sequence Identity: 20% (63 aa)

FSEASKIG----GSVFRALVRG--ADVAI-VQKKGSFVGNYIELLKIITSVHHVNLVKVLGACLRESEHVYVCYEYEEG--VNLREALHSPRAEG----F
.    |||    |.|...  ..    ||| . |    . . |..||     || |.|| ....    .|.|.. || .|   .|.. ... . .|    |
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK----HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

SALASWTSRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNELRAKIVKFGIPQLPRRKLVRKNSIKITGTPGYMSPEYQTSGVVSS-KMDVFAFG
.    .     ..  ....|||.|.|    ..|  .|  || ...  . ||  ||.  .            . ||| ||.||       .  | |. ..|
PE-HAR----FYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCG

VVLLELLTGKQ--PGVQLDPATKKLKVVSLTDEVTEIMEERDPRKKLRLWIDARLRDSYPVDTAMSVAALARLCIDSNPESRPPMKNVTA-----KLSNY
..| |.|.|.   |  |..   ||..                                       ..  . | | . .|| ||    . .     |.  .
CILYEMLCGYPPFP--QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

L
.
F
Kinase LysM_d-2.AA Pkinase 165-325 24 7.5e-12 42.99 Pfam 51-211 (293) Show / Hide 
Range on Protein: 165-325
Range on HMM: 51-211/293
Sequence Identity: 24% (42 aa)

LKIITSVHHVNLVKVLGACLRESEHVYVCYEYEEGV----NLREALHSPRAEGFSALASWTSRLQVALDVALGLEYLHDHTMPPFVHKHVKSTNIIVTNE
..|  ...| | |. .... . . |.|.. || ||      | . ..  ...|     |.     ... .. ||||.|..    ..|  .|. || . |.
IQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNN

LRA----KIVKFGIPQLPRRKLVRKNSIKITGTPGYMSPEY-QTSGVVSSKMDVFAFGVVLLELLTGKQP
       ||  ||.  . .          ..|||.||.||  ...   ..| |....|..| |.|.|. |
GHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase LysM_d-2.AA Pkinase_Tyr 165-247 29 1.7e-11 39.54 Pfam 54-134 (270) Show / Hide 
Range on Protein: 165-247
Range on HMM: 54-134/270
Sequence Identity: 29% (25 aa)

LKIITSV-HHVNLVKVLGACLRESEH--VYVCYEYEEGVNLREALHSPRAEGFSALASWTSRLQVALDVALGLEYLHDHTMPPFVH
.|| ..  || |.|. .|.|....|.  .|.  || .. .|.. |...| |.  .|   .  || ....| |.|||...    ..|
AKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR-EDKQPLTMKD-LLQMCWQIAKGMEYLESKN---CIH
Kinase LysM_d-2.AA UTK 165-238 29 1.3e-09 29.06 In-house 60-135 (296) Show / Hide 
Range on Protein: 165-238
Range on HMM: 60-135/296
Sequence Identity: 29% (23 aa)

LKIITSVH-HVNLVKVLGACLRESEHVYVCYEYEEGVNLRE--ALHSPRAEGFSALASWTSRLQVALDVALGLEYLH
| .   .| |.|.....| |..|.   .. .|| |. .||     |.| .... .. . ..||. |.|.| |..|||
LQMMKQFHWHPNVLRLVGVCTQEEP-WMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLH
Kinase LysM_d-2.AA Pkinase_Tyr 293-403 21 0.000107 16.53 Pfam 181-270 (270) Show / Hide 
Range on Protein: 293-403
Range on HMM: 181-270/270
Sequence Identity: 21% (25 aa)

MSPEYQTSGVVSSKMDVFAFGVVLLELLT-GKQPGVQLDPATKKLKVVSLTDEVTEIMEERD----PRKKLRLWI-DARLRDSYPVDTAMSVAALARLCI
|.||    |. ..| || .|||.. |..| |.||                           .    .   .  .| . . |   | ..   .  | ..| 
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQP---------------------------TYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCW

DSNPESRPPMKNVTAKL
. .|| || .. .  .|
HYDPEDRPTFSEIHEQL
Kinase LysM_d-2.AA UTK 365-403 25 0.000732 9.1 In-house 258-296 (296) Show / Hide 
Range on Protein: 365-403
Range on HMM: 258-296/296
Sequence Identity: 25% (10 aa)

RLRDSYPVDTAMSVAALARLCIDSNPESRPPMKNVTAKL
|.|   | |  ..|  | . |  ..|. || .. .....
RYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase LysM_d-2.AA UTK 293-322 41 0.00102 8.6 In-house 206-236 (296) Show / Hide 
Range on Protein: 293-322
Range on HMM: 206-236/296
Sequence Identity: 41% (13 aa)

MSPEYQTSG-VVSSKMDVFAFGVVLLELLTG
|.||  |..   ..| ||..||||. |..|.
MAPEALTHHTRFTTKSDVWSFGVVCWEIWTW
Kinase LysM_d-2.AA MLK 385-403 26 0.021667 4.26 In-house 273-291 (291) Show / Hide 
Range on Protein: 385-403
Range on HMM: 273-291/291
Sequence Identity: 26% (5 aa)

CIDSNPESRPPMKNVTAKL
| ...|..|| .. .  .|
CWNQDPHKRPSFRQIVQHL
Kinase LysM_d-2.AA Dicty4 385-405 26 0.037879 3.16 In-house 255-277 (277) Show / Hide 
Range on Protein: 385-405
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CIDSNPESRPPMKNVTAK--LSN
| | .|..|| .. .. .  |  
CWDHDPQHRPSFEEIIQRRILEH
Kinase LysM_d-2.AA HH498 387-403 29 0.068843 1.32 In-house 268-284 (284) Show / Hide 
Range on Protein: 387-403
Range on HMM: 268-284/284
Sequence Identity: 29% (5 aa)

DSNPESRPPMKNVTAKL
. .||.||    . ..|
HPCPENRPDFDQIVTIL
Kinase LysM_d-2.AA LRRK 384-405 27 0.086616 2.09 In-house 330-351 (351) Show / Hide 
Range on Protein: 384-405
Range on HMM: 330-351/351
Sequence Identity: 27% (6 aa)

LCIDSNPESRPPMKNVTAKLSN
.| . .|..|| .  .. .|| 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LysM_d-2.AA IRAK 128-150 24 0.195895 1.05 In-house 1-29 (317) Show / Hide 
Range on Protein: 128-150
Range on HMM: 1-29/317
Sequence Identity: 24% (7 aa)

FSEASKIG----GSVFRALVRGAD--VAI
|... .||    | |.|.  .. .  .|.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAV