Gene SD21_o (S.moellendorffii)

SD21_o

Species: S.moellendorffii
Alias: SD21_o
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD21

Sequence

Name Sequence Type Origin Length Description Download
SD21_o.AA Protein None 531 None Fasta, JSON
SD21_o.NA RNA None 1596 None Fasta, JSON
SD21_o.kin_dom Protein Kinase Domain None 200 None Fasta, JSON

Protein domain

Protein domains of SD21_o.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SD21_o.AA TKL 171-440 21 1.1e-58 201.24 In-house 1-364 (364) Show / Hide 
Range on Protein: 171-440
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)

LGDGGFGLVYEGTLKD---------GSKVAVKMLERTSTQGE---------------------------KEFKAEVSVMATVRHLNLIRLRGYCAQGPR-
.| |||| || |...          |  ||||.. ... . .                           .... |. .|   || |.... ||| ..|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILIYDFMPNSSLDKWLFITPAGKDCMLDWSRRYSIALGTARGLAYLHE----ECSQK--IIHLDVKPENILLDQNFL----------
              ......|. ||   |            |..| ..||..|||..|||      |  |  ||| | |..|||.|.|.           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PKVSDFGLAKLMDRDKS------------------RVVTNMRGTPGYLAPEWLHGT----------------AVTAKADVYSFGMVLLELICGRET
    .|..||||.. |.....                      . .|||...||| | |.                  . |.||||||.|| |...... 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

IDLSKGSEQWYLP--------AWAVRMVEEGRPMELIDE---QLHEEVEYFYEDQA-KRSIRVALCCIQEDPTQRPTMGRVVQML
      ....| |        ....  ...|.. .. ..    .  .     .... .. .. . .| ..||..||.. .... |
----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH--K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SD21_o.AA Pkinase 165-440 23 3e-51 181.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 165-440
Range on HMM: 1-293/293
Sequence Identity: 23% (75 aa)

NNFSVKLGDGGFGLVYEGTLKDGSK-VAVKMLERTSTQGEKEFKA-----EVSVMATVRHLNLIRLRGYCAQGPRRILIYDFMPNS----SLDKWLFITP
  .  |.| |.|| ||... |. .| |||| ...  .. ... ..     |...|. ..| | .||....  ...  .. .....     .|  ..    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--

AGKDCML--DWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLP----KVSDFGLAKLMDRDKSRVVTNMRGTPGYLAPEWLH-GTAVTA
  ... .  ..    .... ..|||.|.|..   .||| |.||||||.|.|  .    |..||||||..|  ...  |   |||.|.|||..  |.  . 
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KADVYSFGMVLLELICGRETIDLSKGSEQWYLPAWAV----------RMVEEGRPMELIDEQLHEEVEYFYEDQA-----------KRSIRVALCCIQED
|.|..|.| .| |..|||             .| .            .... ..|    |..   .. ||. ..            .  . .  .|.. |
KVDMWSCGCILYEMLCGR-------------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRHWHFHWTFHNWSEECKDFIKWCLCKD

PTQRPTMGRVVQM--L
|..|||   ..|   .
PKKRPTAEQILQHPWF
Kinase SD21_o.AA IRAK 166-365 36 8.4e-50 171.77 In-house 2-221 (317) Show / Hide 
Range on Protein: 166-365
Range on HMM: 2-221/317
Sequence Identity: 36% (81 aa)

NFSVKLGDGGFGLVYEGTLKDGS-KVAVK----MLERTSTQGEKEFKA---EVSVMATVRHLNLIRLRGYCAQGPRRILIYDFMPNSSLDKWLFITPAGK
. . ..| |||| || | .|     .|||    | . . .. ...| .   |. |... || |.  | |||....   |.|..||| ||   |  .  . 
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQ--DG

DCM---LDWSRRYSIALGTARGLAYLHEECSQ-KIIHLDVKPENILLDQNFLPKVSDFGLAKLM----DRDKSRV----VTNMRGTPGYLAPEWLH--GT
.|.   | | .| ||..|||.|. .||.  .   ||| |.|. ||||||.| || .||||.       .. |. .    .   |||  |..|| .     
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

AVTAKADVYSFGMVLLELICGR
  | | |||||| ||||.. |.
QLTKKTDVYSFGIVLLEVLTGC
Kinase SD21_o.AA Dicty4 166-361 33 9.7e-43 140.46 In-house 2-210 (277) Show / Hide 
Range on Protein: 166-361
Range on HMM: 2-210/277
Sequence Identity: 33% (71 aa)

NFSVKLGDGGFGLVYEGTLKDGSKVAVKML----ERTSTQGEKEFKAEVSVMATVRHLNLIRLRGYCA----QGPRRILIYDFMPNSSLDKWLFI--TPA
|. ...|.|.|| || || . |..||||.|    .  .    .||..||. |.  || |.. . |.|     . ..      .||  .| . |       
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

GKDCMLDWSRRYS---IALGTARGLAYLHE-ECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLMDRDKSRVV--TNMRGTPGYLAPEWLHGTAVTAKA
 .   |||... .   .|. .|||...||.  .   |||.| |. |.| |.|.  ||.||||...| ....     . . |||.. ||| . . . . ||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGMVLLEL
||||||.|| |.
DVYSFGIVLWEI
Kinase SD21_o.AA TKL-Unique 167-362 30 1.6e-40 140.6 In-house 1-222 (290) Show / Hide 
Range on Protein: 167-362
Range on HMM: 1-222/290
Sequence Identity: 30% (68 aa)

FSVKLGDGGFGLVYEGTLKDGSKVAVKMLER---TSTQGEKEFKAEVSVMATVR-HLNLIRLRGYCA----QGPRRILIYDFMPNSSLDKWLF-ITPAG-
|. |.| ||.| || |. . |..||.| ..     | . ..||. ||..| . . | |. .. |||.    . |..... ...| .||.. |    .   
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

---KDCMLDWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQN-----FLPKVSDFGLAKLMDRDKSRVVTNM--------RGTPGYLAPEWL
   . | |....|...|.  |.|. ||| .    |||.| |. |.|.|.|     .  |..||||.|. ...    ...          |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

HG--TAVTAKADVYSFGMVLLELI
 .  .  . |.||||||.|| |..
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase SD21_o.AA S_TKc 165-444 22 3.8e-37 130.63 SMART 1-231 (231) Show / Hide 
Range on Protein: 165-444
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

NNFSVKLGDGGFGLVYEGTLKD-GSKVAVKMLERTSTQGEKEFKAEVSVMATVRHLNLIRLRGYCAQGPRRILIYDFMPN--SSLDKWLFITPA-GKDCM
  .  |.| |.|| || .. |. | .||.|..        . .. |....   .| |...| ...    .  .. .....   .| . .   .  |... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLMDRDKSRVVTNMRGTPGYLAPEWLHGTAVTA-KADVYSFGMVLL
..  .  ...  ....|.|.|   |..||| |.||||||||.    |..|||||...        | . ||| |.||| |     .  |.|..|.| .| 
FPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELICGRETIDLSKGSEQWYLPAWAVRMVEEGRPMELIDEQLHEEVEYFYEDQAKRSIRVALCCIQEDPTQRPTMGRVVQ-----MLDGLV
|..||.   .          ..   ...                         .  .     | | ||..|||   . |     ...  .
EMLCGYPPFP---------QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD21_o.AA TK 170-361 16 7.8e-35 113.65 In-house 6-387 (486) Show / Hide 
Range on Protein: 170-361
Range on HMM: 6-387/486
Sequence Identity: 16% (64 aa)

KLGDGGFG---LVYEGTLKDGS--------------------------KVAVKMLERTSTQGEKEFKA--------------EVSVMATVR-----HLNL
||| | ||    ||.|......                          .||||||  .... ..||..              |...|.  .     | |.
KLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHHPNI

IRLRGYCAQG------------PRRILIYDFMPNSS----LDKWLFITPAGKDCM---------------------------------------------
.|| |.| ||            .  ...  .||. .    |...|   . .. ..                                             
VRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDDDLI

--------------------------LDWSRRYSIALGTARGLAYLHEE----CSQKIIHLDVKPENILLDQNFL-----------PKVSDFG-------
                          |.  ..  ...  |.|..|||.       |...| |.   |.|...|              |..|||       
KDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSG

-LAKLMDRDKSRVVTNMRGTPG-------------------------YLAPEWLHGTA---------VTAKADVYSFGMVLLEL
 ||. ...|.  .... .||..                         ..||| | .            | | ||.||| .. |.
VLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase SD21_o.AA MLK 165-366 25 6e-34 115.19 In-house 1-234 (291) Show / Hide 
Range on Protein: 165-366
Range on HMM: 1-234/291
Sequence Identity: 25% (60 aa)

NNFSVKLGDGGFGLVYEGTLKDGS----KVAVKMLE-------RTSTQGEKEFKAEVSVMATVRHLN----LIRLRGYCAQGPR-RILIYDFMPNSSLDK
 .|. ..| |.|| |. |. .        ||||. .       .|...  ..|. |.   . ..|.|     |...| |.| |    ..  .....||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCE-QWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WL---FITPAG------KDCMLDWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQ------NFLPKVSDFGLAKLMDRDKSRVVTNMRGTPG
 |    . ...       |   | .   ..||  |||..|||..  ..||| | |. |||.|.      .   |..|||... . . .    ....||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLAPEWL---HGTAVTAKADVYSFGMVLLELICGRE
. ||| .    .. .. |.||.|.|.|| |.. ...
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREV
Kinase SD21_o.AA LRRK 157-362 23 3.5e-32 111.16 In-house 1-276 (351) Show / Hide 
Range on Protein: 157-362
Range on HMM: 1-276/351
Sequence Identity: 23% (67 aa)

FKQVRKITNNFSVKLGDGGFG-LVYEGTLKD---------------------------GSKVAVKMLERT------------------------------
.|  ..        .|.|||| .|| .....                           ...||.| ..|.                              
LKIEEQ--------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQ

----STQGEKEFKAEVSVMATVRHLNLIRLRGYCAQGPRRILIYDFMPNSSLDKWLFITPAGKD----CMLDWSRRYSIALGTARGLAYLHEECSQK--I
    ..    ||  ||..| . .| |.. | |.| . |... . ...|. .|.. |. .   .       ..|. .. |||  |.|..|||   |..  |
NHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCM-VMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPI

IHLDVKPENILL---D---------QNFLPKVSDFGLAKLMDRDKSRVVTNMRGTPGYLAPEWLHGT---AVTAKADVYSFGMVLLELI
|| | |..||||   .         ..   |..|||.  .   ... |.  . |.||..||| . ..     | |.|.|||||.| ||.
IHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELL
Kinase SD21_o.AA DRK 166-362 35 1e-31 104.74 In-house 2-196 (258) Show / Hide 
Range on Protein: 166-362
Range on HMM: 2-196/258
Sequence Identity: 35% (71 aa)

NFSVKLGDGGFGLVYEGTLKDGSKVAVKMLERTSTQGE---KEFKAEVSVMATVRHLNLIRLRGYCAQGPRRILIYDFMPNSSLDKWLFITPAGKDCMLD
   .  | |..| |. ||   |..||||||       |   .||. |. .|   || | .   | |   |    .  .||  || . |          .|
KIGNRIGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH----DESIEMD

WSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLMDRDKSRVVTN-MRGTPGYLAPEWLHGTAVTAKADVYSFGMVLLEL
|... ....  |.|. |||  |   ||| | |  | | | ..  ||.||||.    . |..  .  | |||.  ||| |     | |||||||. || |.
WPLMKQMMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWEC

I
.
V
Kinase SD21_o.AA Pkinase_Tyr 166-362 29 1.5e-26 90.51 Pfam 2-208 (270) Show / Hide 
Range on Protein: 166-362
Range on HMM: 2-208/270
Sequence Identity: 29% (63 aa)

NFSVKLGDGGFGLVYEGTLK-----DGSKVAVKMLERTSTQGE---KEFKAEVSVMATV-RHLNLIRLRGYCA-QGPR--RILIYDFMPNSSLDKWLFIT
 |  ||| | || ||.||.|     .. .||||||  .... .   ..| .|...| .  .| |..|| | |  ||     ...  .||. .|.. |   
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

-PAGKDCMLDWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLM-DRDKS-RVVTNMRGTPGYLAPEWLHGTAVTAKAD
 . ..   . .    ....  |.|..||.   |...|| |.   |.|.. |.  |..|||||... . |   |. .. .     .||| ..    | | |
REDKQPLTMKD--LLQMCWQIAKGMEYLE---SKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSD

VYSFGMVLLELI
|.||| .. |..
VWSFGVLMWEIF
Kinase SD21_o.AA Dicty4-Unclassified 269-366 37 7.8e-26 85.44 In-house 114-206 (263) Show / Hide 
Range on Protein: 269-366
Range on HMM: 114-206/263
Sequence Identity: 37% (37 aa)

IALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLMDRDKSRVVTNMRGTPGYLAPEWLHGTAVTAKADVYSFGMVLLELICGRE
.|.  |.|...||   .  .|| |.|  |||.| .|  |. |||..   |       |   |||   .|| | . . . |.||||..|.| ||. | |
YAFDIAQGMQHLH---TRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN--MTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDE
Kinase SD21_o.AA TyrKc 165-440 24 3.1e-22 81.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 165-440
Range on HMM: 1-280/280
Sequence Identity: 24% (74 aa)

NNFSVKLGDGGFGLVYEGTLKDGSKVAVKMLERTSTQGEKEFKAEVSVMATV--RHLNLIRLRGYCAQG-------PRRILIYDFMPNSSLDKWLFITPA
  .  ||| | || ||.||.|   .||||||   .   ...|  | ..|  .  .| |..|| |.| |.       .   ..  .||. .|.. |  .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

GKDCMLDWSRRYSIALGTARGLAYLHEECSQKIIHLDVKPENILLDQNFLPKVSDFGLAKLMDRD------KSRVVT----NMR--GTPGYLAPEWLHGT
     | ..   |...  |.| .|||.    ..|| |    |.|.. |.  |.|||||..  . |      |.  ..    . .       .||| .   
K----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

AVTAKADVYSFGMVLLELICGRETIDLSKGSEQWYL-------PAWAVRMVEEGRPMELIDEQLHEEVEYFYEDQAKRSIRVALCCIQEDPTQRPTMGRV
  | | ||.||| .. |.        .. | . ..        .. ... |..|. |.  .. . . . .  .  ..    . ..| .||| .|||.  .
KFTTKSDVWSFGVCMWEI--------FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-P-MSF-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI

VQML
.. .
HECF
Kinase SD21_o.AA CAMK 285-365 25 5.8e-22 66.92 In-house 197-331 (425) Show / Hide 
Range on Protein: 285-365
Range on HMM: 197-331/425
Sequence Identity: 25% (35 aa)

SQKIIHLDVKPENILLDQN-----------------FLPKVSDFGLAKLMDRDK----------------------SRVVTNMRGTPGYLA-PEWLHG--
|..|.|.| ||||||||.|                 .  |..|||.|. .|...                          . . |||.| | ||.| |  
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

------------TAVTAKADVYSFGMVLLELICGR
            . .. |.|. | | .|  . ||.
HCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGY
Kinase SD21_o.AA CAMK 170-224 17 3.3e-14 41.47 In-house 1-103 (425) Show / Hide 
Range on Protein: 170-224
Range on HMM: 1-103/425
Sequence Identity: 17% (18 aa)

KLGDGGFGLVYEGTLK-DG------------SKVAVKMLERT----------------------------STQGEKEFKAEVSVMAT-------VRHLNL
.|| |.|| |.... | ..             |||.|.....                            . . .|... |...| .       ..| |.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRL
|.|
IKL
Kinase SD21_o.AA Dicty4-Unclassified 166-228 31 1e-07 22.47 In-house 2-67 (263) Show / Hide 
Range on Protein: 166-228
Range on HMM: 2-67/263
Sequence Identity: 31% (21 aa)

NFSVKLGDGGFGLVYEGTLKDGSKVAVKMLERTSTQGE----KEFKAEVSVMATVRHLNLIRLRGYC
     .| | |  |. |  | |  |||| .   . .      ..||.|| ..  . | ||....|||
QIDQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC
Kinase SD21_o.AA DRK 422-442 38 5e-06 16.51 In-house 238-258 (258) Show / Hide 
Range on Protein: 422-442
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CIQEDPTQRPTMGRVVQMLDG
|  |||..||.|  ... |. 
CWNEDPQHRPSMQECLERLEA
Kinase SD21_o.AA TK 417-440 29 1.7e-05 13.6 In-house 463-486 (486) Show / Hide 
Range on Protein: 417-440
Range on HMM: 463-486/486
Sequence Identity: 29% (7 aa)

RVALCCIQEDPTQRPTMGRVVQML
.. ..| ..|| .|||.  ....|
DLMQQCWHYDPEDRPTFSQLHEQL
Kinase SD21_o.AA Dicty4-Unclassified 422-440 47 0.000116 11.85 In-house 245-263 (263) Show / Hide 
Range on Protein: 422-440
Range on HMM: 245-263/263
Sequence Identity: 47% (9 aa)

CIQEDPTQRPTMGRVVQML
|  .||  ||||  ..| |
CWHNDPNKRPTMNQIIQYL
Kinase SD21_o.AA MLK 421-440 40 0.000724 9.45 In-house 272-291 (291) Show / Hide 
Range on Protein: 421-440
Range on HMM: 272-291/291
Sequence Identity: 40% (8 aa)

CCIQEDPTQRPTMGRVVQML
.| ..|| .||..  .|| |
QCWNQDPHKRPSFRQIVQHL
Kinase SD21_o.AA Dicty4 422-442 30 0.002186 7.35 In-house 255-277 (277) Show / Hide 
Range on Protein: 422-442
Range on HMM: 255-277/277
Sequence Identity: 30% (7 aa)

CIQEDPTQRPTMGRVVQM--LDG
|  .||..||..  ..|   |. 
CWDHDPQHRPSFEEIIQRRILEH
Kinase SD21_o.AA Pkinase_Tyr 420-440 33 0.004506 11.03 Pfam 250-270 (270) Show / Hide 
Range on Protein: 420-440
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LCCIQEDPTQRPTMGRVVQML
. | ..|| .|||.  ....|
KQCWHYDPEDRPTFSEIHEQL
Kinase SD21_o.AA LRRK 422-442 38 0.010623 5.36 In-house 331-351 (351) Show / Hide 
Range on Protein: 422-442
Range on HMM: 331-351/351
Sequence Identity: 38% (8 aa)

CIQEDPTQRPTMGRVVQMLDG
| |.||..||..  .|. |  
CWQHDPKKRPHFSQIVKRLSQ
Kinase SD21_o.AA TKL-Unique 422-440 36 0.175955 1.21 In-house 272-290 (290) Show / Hide 
Range on Protein: 422-440
Range on HMM: 272-290/290
Sequence Identity: 36% (7 aa)

CIQEDPTQRPTMGRVVQML
|   ||.|||.   ..  |
CWHHDPSQRPSFDEIIHRL