Gene SD21_j-2 (S.moellendorffii)

SD21_j-2

Species: S.moellendorffii
Alias: SD21_j-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD21

Sequence

Name Sequence Type Origin Length Description Download
SD21_j-2.AA Protein None 788 None Fasta, JSON
SD21_j-2.NA RNA None 2367 None Fasta, JSON
SD21_j-2.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of SD21_j-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin SD21_j-2.AA B_lectin 84-176 31 3.2e-23 81.39 Pfam 1-127 (137) Show / Hide 
Range on Protein: 84-176
Range on HMM: 1-127/137
Sequence Identity: 31% (40 aa)

SAQVVWSANGN---NPV-----GENSTLTLNG-DGVLMILDET-G-RI--VWNT--PPNLQV--Q--AMELQASGNLVLQ-SNS--SSTLWQS--FASPG
.  |||.|| .   |||     ..|.|||. . || | ..|   | ..  ||.|    .         ...| ||||||  .|.  ...||||  |  |.
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DTLVEGQALRA------G--W--RMSS
||.  |. |..      .  |  ...|
DTWLPGMKLGWDNNVTIYMNWIGYLTS
B_lectin SD21_j-2.AA B_lectin 41-158 26 4.2e-15 57.43 SMART 1-126 (126) Show / Hide 
Range on Protein: 41-158
Range on HMM: 1-126/126
Sequence Identity: 26% (35 aa)

FVYLNQSGSTVSYMLILVRGNFGCGFYGNSSSFVFGVVIFRESSA----QVVWSA--NGNNPVGE---NSTLTLNGDGVLMILDETGRIVWNTPPN--LQ
  .|..  . ||   .     | .||.   ..  . . |  ...     .|||.|  | .||| .   ...||.. || | |.|  .|.|| .  .    
DNTLSSGQTLVSGNSLFE---FYLGFFTFIMQ--WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNG

VQAMELQASGNLVLQSNS----SSTLWQSFASP
. ...|| .||.|. ...    . ..|||| .|
NYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
Kinase SD21_j-2.AA TKL 496-774 21 3.9e-61 209.41 In-house 1-364 (364) Show / Hide 
Range on Protein: 496-774
Range on HMM: 1-364/364
Sequence Identity: 21% (87 aa)

LGQGGFGSVFLATLKD---------GSQVAVKRLES----------------------------SSQGQKEFKTEVNVISSIHHFNLVRLRGFCAEKHH-
.|.|||| |. ....          |  ||||.. |                            .|. ..... |....|...| |.|.. |.| .  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEYMPRRSLDKWLFLRDFPSDGDHEKAGEALDWKTRLRIALGIARGLKYLHE----DCSER--ILHLDVKPQNVLLDSNFD---
              .|.||.|. ||   |                   |  |.|.||.||||. |||      |     |.| | |..|.|.|.|.    
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVS

-----------AKLCDFGMSKLMKRNESEVFTM------------------MRGTRGYLAPEWLQ-----------------STITERVDVYSFGIVLLE
           .|.|||| |. |.....   ||                   .|| ...||| |.                 .. .|..||||||||| |
NYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE

IVSGQRCLGNSRAETSTQYFPNWASSRICR----GQIMEIADSSLQGELQ------SGMVALWEQVEL---VIYTAMWCIQEDSAQRPSMEMAIRML
|....|            |. .. ...|..      .| ..| .|. ..         . . .        ..  ...| ..|  .|||..  .  |
ILTRCR-----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase SD21_j-2.AA Pkinase 490-695 26 6.7e-54 190.18 Pfam 1-209 (293) Show / Hide 
Range on Protein: 490-695
Range on HMM: 1-209/293
Sequence Identity: 26% (60 aa)

NNFGKKLGQGGFGSVFLATLKDGSQ-VAVKRLESSSQGQKEFKT-----EVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRR----SLDKWLFLRDF
  .|.|.|.|.||.|.... |. .. ||||... ...  .. .|     |. .  ...| | |||.... .| |  .| ||..      .|  ..     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

PSDGDHEKAGEAL--DWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSNFDA----KLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQ-
       ... ..  ....  .... |.|||.|.|.    .|.| |.||.|.|.|.| .     |.|||| .|...   .. .|   ||..|.|||... 
-------WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

-STITERVDVYSFGIVLLEIVSGQ
 . .. .||..|.|..| | ..|.
GQYYGPKVDMWSCGCILYEMLCGR
Kinase SD21_j-2.AA TKL-Unique 492-696 30 1.1e-47 164.7 In-house 1-226 (290) Show / Hide 
Range on Protein: 492-696
Range on HMM: 1-226/290
Sequence Identity: 30% (72 aa)

FGKKLGQGGFGSVFLATLKDGSQVAVKRLE--SSSQGQ--KEFKTEVNVISSIH-HFNLVRLRGFCA----EKHHRLLVYEYMPRRSLDKWLFLRDFPSD
|..|.|.||.|.|. .. . |..||.|...  ..|  .  .||. |||... .| | |.|.. |.|.       .. .| ||.|. ||.. |        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL--------

GDHE--------KAGEALDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSN-----FDAKLCDFGMSKLMKRNESEVFTMM--------RG
  |         .    |... |...|. ||.|. |||      |.|.| |..|.|.|.|     . .|.|||| ||. ...  . ...          |
--HQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCG

TRGYLAPEWLQS---TITERVDVYSFGIVLLEIVSGQR
.  ..||| | .   ...| .||||||||| ||.....
SFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase SD21_j-2.AA IRAK 491-707 33 7.1e-46 158.72 In-house 2-233 (317) Show / Hide 
Range on Protein: 491-707
Range on HMM: 2-233/317
Sequence Identity: 33% (80 aa)

NFGKKLGQGGFGSVFLATLKDGS-QVAVKRL---ESSSQGQ--KEFKT---EVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPS
. . ..|.|||| |. . .|     .|||.|   ...|...  ..| .   |. | ....| |.| | |.|.|     |||.|||  ||   |  .|   
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD---

DGDHEKAGEALDWKTRLRIALGIARGLKYLHEDCSE-RILHLDVKPQNVLLDSNFDAKLCDFGMSKLM---KRNESEVFTMM-----RGTRGYLAPEWLQ
      .  .| | .|. |..|.|.|. .||.. .   | | |.|. |.||| .| .|.||||.         .|. . |.|     |||  |..|| . 
---GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIR

---STITERVDVYSFGIVLLEIVSGQRCLGNSRAETST
     .| ..|||||||||||...|.|   . |.|. .
DPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYY
Kinase SD21_j-2.AA Dicty4 491-695 35 1e-44 147.16 In-house 2-214 (277) Show / Hide 
Range on Protein: 491-695
Range on HMM: 2-214/277
Sequence Identity: 35% (78 aa)

NFGKKLGQGGFGSVFLATLKDGSQVAVKRL-----ESSSQGQKEFKTEVNVISSIHHFNLVRLRGFCA----EKHHRLLVYEYMPRRSLDKWLFLRDFPS
|.....|.|.||.|...| . |..|||| |      ...   .||. ||.  ..| | |.. . | |     ..   . | ||||. .| .   |.| ||
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYS--LLHDKPS

DGDHEKAGEALDWKTRLR---IALGIARGLKYLHE-DCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVF-TM-MRGTRGYLAPEWLQSTI
.   ..    ||| ...|   .|. .|||. .||. ..  .|.|.| |. | | | |. .| |||| |..||. |.  . .| . || .. ||| ...  
EQQQSI---KLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

-TERVDVYSFGIVLLEIVSGQ
 .| .||||||||| ||. .|
YNEKADVYSFGIVLWEILTRQ
Kinase SD21_j-2.AA MLK 490-695 26 1.8e-37 127.56 In-house 1-233 (291) Show / Hide 
Range on Protein: 490-695
Range on HMM: 1-233/291
Sequence Identity: 26% (62 aa)

NNFGKKLGQGGFGSVFLATLKDGS----QVAVKRLE-------SSSQGQKEFKTEVNVISSIHHFN----LVRLRGFCAEK-HHRLLVYEYMPRRSLDKW
 .| ...| |.||.|.... .        ||||| .       ...  |..|..|..  . . | |     ....| |..  .| ..| ||..  ||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LFL-RDFPSDGDHEKAGEA----LDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDS------NFDAKLCDFGMSKLMKRNESEVFTMMRGT
|   |. ..|      ..      |    ...|| .|||. |||..    | | | |..|.|.|       . ..| |||| |. ..... .  . ..||
LHGARSKWMDAN---HNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGT

RGYLAPEWL----QSTITERVDVYSFGIVLLEIVSGQ
  . ||| .     .. .| .||.|.|.|| |.....
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
S_TKc SD21_j-2.AA S_TKc 490-774 21 4.3e-37 130.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 490-774
Range on HMM: 1-231/231
Sequence Identity: 21% (63 aa)

NNFGKKLGQGGFGSVFLATLKD-GSQVAVKRLESSSQGQKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPR--RSLDKWLFLRDFPSDGDHE
  ...|.|.|.||.|.... |. | .||.|..       . .. |... .. || |.|.| ... . .|  .| ||..    .| . .  |  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH------

KAGEALDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQSTITE-RVDVYSFG
. .  ..  .  ...  |...|.|.|   | .|.| |.||.|.|||.    |.||||.....        | . ||. |.||| |    .  ..|..|.|
GLRFPFPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCG

IVLLEIVSGQRCLGNSRAETSTQYFPNWASSRICRGQIMEIADSSLQGELQSGMVALWEQVELVIYTAMWCIQEDSAQRPSMEMAIR---------ML
..| | ..|.                          |.... .  .               . ..   . | | | ..||.   | .          .
CILYEMLCGYPPFP----------------------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD21_j-2.AA Pkinase_Tyr 491-693 29 1.1e-34 118.12 Pfam 2-209 (270) Show / Hide 
Range on Protein: 491-693
Range on HMM: 2-209/270
Sequence Identity: 29% (64 aa)

NFGKKLGQGGFGSVFLATLK-----DGSQVAVKRL--ESSSQG--QKEFKTEVNVISSI-HHFNLVRLRGFCA-EKHH--RLLVYEYMPRRSLDKWLFLR
 ||||||.| ||.|...|.|     .. .|||| |   ....   ...|  |... ... || |.||| | |  .. .   ..| ||||  .|.. |  .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

DFPSDGDHEKAGEALDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTMMRGTRG---YLAPE-WLQS
           ...|. |. | ... ||.|. ||..     . | |.   |.|...|. .| ||||.....   .   ...  |..     .||| .  .
R--------EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYG

TITERVDVYSFGIVLLEIVS
  |.  ||.|||... ||..
KFTTKSDVWSFGVLMWEIFT
Kinase SD21_j-2.AA LRRK 490-696 26 1.3e-34 119.9 In-house 1-281 (351) Show / Hide 
Range on Protein: 490-696
Range on HMM: 1-281/351
Sequence Identity: 26% (76 aa)

NNFGKKLGQGGFG-SVFLATLKD---------------------------GSQVAVKRLES----------SSQG-------------------------
  .....|.|||| .|. |....                           .. ||.| ..           .| .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPSDG-DHEKAGEALDWKTRLRIALGIARGLKYLHEDCSER--ILHLD
  ||  || ..|. .| |.| | |||   |.. .| ||.|  .|..  ||... .||    |    ..| ..|.||| ||.|..|||   | .  |.| |
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYH--FLHNKKQDGFHFMK--AHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRD

VKPQNVLL---D---------SNFDAKLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQ----STITERVDVYSFGIVLLEIVSGQ-R
 |. |.||   .          .  ||..||| | . .   ..|.  . |. |..||| ..    .. || ||.||||..| |....| .
LKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase SD21_j-2.AA Ciliate-E2 490-696 18 7.9e-32 106.52 In-house 1-294 (365) Show / Hide 
Range on Protein: 490-696
Range on HMM: 1-294/365
Sequence Identity: 18% (58 aa)

NNFGKKLGQGGFGSVFLATL-KDGSQVA---------------------VKRLESSSQGQKEFKTEVNVISSIH----------------HFNLVRLRGF
 .| ||.|||.||||....  |.. |.|                     .     . .. ...| | ...  |.                | |....  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CA--EKHHRLLVYEYMPRRSLDKWL------FLRDFPSDGDHEKAGEALDWKTRLRIALGIAR---------------GLKYLHEDCSERILHLDVKPQN
     ...  || ||    .| ...      ..  ..     . . . ...| ...|   |..               .|.|||.  .  |.| | ||.|
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE-----K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPEN

VLLDSNFDAKLCDFGMSK---LMKRNESEVFTMMR----------------------------GTRGYLAPEWLQST----------ITERVDVYSFGIV
.|.      |..|||.||       |... . ..                             || ||.||| |..            .. .|..|.|..
ILF-----IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVI

LLEIVSGQR
| | ..|..
LYEMLFGKP
Kinase SD21_j-2.AA TK 490-693 17 8.5e-32 103.28 In-house 1-389 (486) Show / Hide 
Range on Protein: 490-693
Range on HMM: 1-389/486
Sequence Identity: 17% (68 aa)

NNFGKKLGQGGFG---SVFLATLKDGS--------------------------QVAVKRLES-SSQGQKEFKT--------------EVNVISSIH----
  .|||||.| ||    |.........                          .|||| | . ... |.||.               |.....  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HFNLVRLRGFCAEK------------HHRLLVYEYMPRRS----LDKWLFLRDFPSDGDHEKAGEA---------------------------------
 | |.||| | | ..            .. ..| ||||  .    |..  .||. . .. ||  . .                                 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRD--YLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQ

---------------------------------LDWKTRLRIALGIARGLKYLHED----CSERILHLDVKPQNVLLDSNFD-----------AKLCDFG
                                 |. ...| ... ||.|. |||.        .. | |.   |.|...|             .|..|||
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG

MSK-----LMKRNES--EVFTMMRGTRGY--------------------------LAPEWLQSTI----------TERVDVYSFGIVLLEIVS
.|.     | .. .|  .  ..  ...|                           .||| |.. .          |.  ||.|||... ||..
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD21_j-2.AA DRK 491-692 35 4.5e-31 102.51 In-house 2-196 (258) Show / Hide 
Range on Protein: 491-692
Range on HMM: 2-196/258
Sequence Identity: 35% (74 aa)

NFGKKLGQGGFGSVFLATLKDGSQVAVKRLESSSQG----QKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPSDGDHE
  |   | |..| ||. |   |.|||||.|           .||. |.|...   | | .   | | .    . . ||||| || . |          |.
KIGNRIGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNIL----------HD

KAGEALDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTM-MRGTRGYLAPEWLQSTI-TERVDVYSF
 . | .||  ...... .|.|. |||  |   |.| | |  | | | ..  |  ||| |   |. ..  |.| | || .  ||| | .   ||  |||||
ESIE-MDWPLMKQMMFDCAKGMIYLHC-CNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSF

GIVLLEIV
.||| |.|
AIVLWECV
Kinase SD21_j-2.AA TyrKc 490-774 23 3.1e-28 101.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 490-774
Range on HMM: 1-280/280
Sequence Identity: 23% (74 aa)

NNFGKKLGQGGFGSVFLATLKDGSQVAVKRLESSSQGQKEFKTEVNVISSI--HHFNLVRLRGFCAEK-------HHRLLVYEYMPRRSLDKWL-FLRDF
  .||||| | || |...|.|   ||||| | ...  ...|  | .. ...  || |.||| | | ..       .  ..| ||||  .|.. |   |. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PSDGDHEKAGEALDWKTRLRIALGIARGLKYLHEDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRN-----ESEVFTMMR--GTRG-----YLA
            | .|. | ... ||.|  |||.    .. | |    |.|...|. .| .|||.|.  .       .... ...   |...      .|
------------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEWLQSTI-TERVDVYSFGIVLLEIVSGQRCLGNSRAE--TSTQYFPNWASSRICRGQIME---IADSSLQGELQSGMVALWEQVELVIYTAMWCIQEDS
|| ..  . |.  ||.|||... || .         ..   | |   ..  ..  . |  .   ..         .      .  . .     .| .|| 
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------F-----VCCPDEMYQIMKQCWHEDP

AQRPSMEMAIRML
..||...  .. .
EDRPTFSEIHECF
Kinase SD21_j-2.AA STE 599-700 25 1.1e-22 77.07 In-house 155-270 (359) Show / Hide 
Range on Protein: 599-700
Range on HMM: 155-270/359
Sequence Identity: 25% (32 aa)

RIALGIARG-LKYLHEDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKR---------------NESEVFTMMRGTRGYLAPEWLQ-------STI
.|.  | .| |.|||.     | | |.||.|.||     .|||||| .. .                 . ..  . . ||  . ||| .|       .  
YICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGY

TERVDVYSFGIVLLEIVSGQRCLGN
....|..|.|....| . |.  . .
DTKCDIWSLGCTIIEMATGKPPWHD
Kinase SD21_j-2.AA STE 490-572 16 5.7e-12 38.66 In-house 1-126 (359) Show / Hide 
Range on Protein: 490-572
Range on HMM: 1-126/359
Sequence Identity: 16% (21 aa)

NNFGKKLGQGGFGSVFLATLKD----------------GSQVAVKRLESSSQG------------------QKEFKTEVNVISSIH--HFNLVRLRGFCA
  . .|.|.|.||.|..|  ..                |  .|.|... ...                   ..... |... .  .  | | |.  | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EK-------HHRLLVYEYMPRRSLDK
 .       ..  .. |||.  |||.
KEGHNHKNDDELWICMEYMDGGSLDD
Kinase SD21_j-2.AA DRK 756-776 42 0.000785 8.9 In-house 238-258 (258) Show / Hide 
Range on Protein: 756-776
Range on HMM: 238-258/258
Sequence Identity: 42% (9 aa)

CIQEDSAQRPSMEMAIRMLEG
|  ||  .||||.  .  || 
CWNEDPQHRPSMQECLERLEA
Kinase SD21_j-2.AA TK 749-774 22 0.01635 3.38 In-house 460-486 (486) Show / Hide 
Range on Protein: 749-774
Range on HMM: 460-486/486
Sequence Identity: 22% (6 aa)

VIYT-AMWCIQEDSAQRPSMEMAIRML
..|   . | ..| ..||...   ..|
EYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SD21_j-2.AA MLK 756-774 31 0.069979 2.47 In-house 273-291 (291) Show / Hide 
Range on Protein: 756-774
Range on HMM: 273-291/291
Sequence Identity: 31% (6 aa)

CIQEDSAQRPSMEMAIRML
| ..|...|||. . .  |
CWNQDPHKRPSFRQIVQHL
Kinase SD21_j-2.AA LRRK 754-776 26 0.205964 0.74 In-house 329-351 (351) Show / Hide 
Range on Protein: 754-776
Range on HMM: 329-351/351
Sequence Identity: 26% (6 aa)

MWCIQEDSAQRPSMEMAIRMLEG
..| |.|  .||...  .  |. 
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase SD21_j-2.AA Pkinase_Tyr 756-774 26 6.771875 0.27 Pfam 252-270 (270) Show / Hide 
Range on Protein: 756-774
Range on HMM: 252-270/270
Sequence Identity: 26% (5 aa)

CIQEDSAQRPSMEMAIRML
| ..| ..||...  ...|
CWHYDPEDRPTFSEIHEQL