Gene SD21_j-1 (S.moellendorffii)

SD21_j-1

Species: S.moellendorffii
Alias: SD21_j-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD21

Sequence

Name Sequence Type Origin Length Description Download
SD21_j-1.AA Protein None 787 None Fasta, JSON
SD21_j-1.NA RNA None 2364 None Fasta, JSON
SD21_j-1.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of SD21_j-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin SD21_j-1.AA B_lectin 84-176 31 3.2e-23 81.39 Pfam 1-127 (137) Show / Hide 
Range on Protein: 84-176
Range on HMM: 1-127/137
Sequence Identity: 31% (40 aa)

SAQVVWSANGN---NPV-----GENSTLTLNG-DGVLMILDET-G-RI--VWNT--PPNLQV--Q--AMELQASGNLVLQ-SNS--SSTLWQS--FASPG
.  |||.|| .   |||     ..|.|||. . || | ..|   | ..  ||.|    .         ...| ||||||  .|.  ...||||  |  |.
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DTLVEGQALRA------G--W--RMSS
||.  |. |..      .  |  ...|
DTWLPGMKLGWDNNVTIYMNWIGYLTS
B_lectin SD21_j-1.AA B_lectin 41-158 26 4.2e-15 57.43 SMART 1-126 (126) Show / Hide 
Range on Protein: 41-158
Range on HMM: 1-126/126
Sequence Identity: 26% (35 aa)

FVYLNQSGSTVSYMLILVRGNFGCGFYGNSSSFVFGVVIFRESSA----QVVWSA--NGNNPVGE---NSTLTLNGDGVLMILDETGRIVWNTPPN--LQ
  .|..  . ||   .     | .||.   ..  . . |  ...     .|||.|  | .||| .   ...||.. || | |.|  .|.|| .  .    
DNTLSSGQTLVSGNSLFE---FYLGFFTFIMQ--WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNG

VQAMELQASGNLVLQSNS----SSTLWQSFASP
. ...|| .||.|. ...    . ..|||| .|
NYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
Kinase SD21_j-1.AA TKL 495-773 21 1.4e-61 210.85 In-house 1-364 (364) Show / Hide 
Range on Protein: 495-773
Range on HMM: 1-364/364
Sequence Identity: 21% (87 aa)

LGQGGFGSVFLATLND---------GSQVAVKRLES----------------------------SSQGQKEFKTEVNVISSIHHFNLVRLRGFCAEKHH-
.|.|||| |. ....          |  ||||.. |                            .|. ..... |....|...| |.|.. |.| .  . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEYMPRRSLDKWLFLRDFPSDGDHEKAGEALDWKTRLRIALGIARGLKYLHD----DCSER--ILHLDVKPQNVLLDSNFD---
              .|.||.|. ||   |                   |  |.|.||.||||. |||      |     |.| | |..|.|.|.|.    
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------------------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVS

-----------AKLCDFGMSKLMKRNESEVFTM------------------MRGTRGYLAPEWLQ-----------------STITERVDVYSFGIVLLE
           .|.|||| |. |.....   ||                   .|| ...||| |.                 .. .|..||||||||| |
NYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE

IVSGQRCLGNSRAETSTQYFPNWASSRICR----GQIMEIADSSLHGELQ------SGMVALWEQVEL---VIYTAMWCIQEDSAQRPSMEMVIRML
|....|            |. .. ...|..      .| ..| .|. ..         . . .        ..  ...| ..|  .|||.. ..  |
ILTRCR-----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase SD21_j-1.AA Pkinase 489-694 26 4.8e-53 187.33 Pfam 1-209 (293) Show / Hide 
Range on Protein: 489-694
Range on HMM: 1-209/293
Sequence Identity: 26% (59 aa)

NNFGKKLGQGGFGSVFLATLNDGSQ-VAVKRLESSSQGQKEFKT-----EVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRR----SLDKWLFLRDF
  .|.|.|.|.||.|....  . .. ||||... ...  .. .|     |. .  ...| | |||.... .| |  .| ||..      .|  ..     
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST---

PSDGDHEKAGEAL--DWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSNFDA----KLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQ-
       ... ..  ....  .... |.|||.|.|.    .|.| |.||.|.|.|.| .     |.|||| .|...   .. .|   ||..|.|||... 
-------WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRG

-STITERVDVYSFGIVLLEIVSGQ
 . .. .||..|.|..| | ..|.
GQYYGPKVDMWSCGCILYEMLCGR
Kinase SD21_j-1.AA TKL-Unique 491-695 30 1.4e-47 164.44 In-house 1-226 (290) Show / Hide 
Range on Protein: 491-695
Range on HMM: 1-226/290
Sequence Identity: 30% (72 aa)

FGKKLGQGGFGSVFLATLNDGSQVAVKRLE--SSSQGQ--KEFKTEVNVISSIH-HFNLVRLRGFCA----EKHHRLLVYEYMPRRSLDKWLFLRDFPSD
|..|.|.||.|.|. .. . |..||.|...  ..|  .  .||. |||... .| | |.|.. |.|.       .. .| ||.|. ||.. |        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVL--------

GDHE--------KAGEALDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSN-----FDAKLCDFGMSKLMKRNESEVFTMM--------RG
  |         .    |... |...|. ||.|. |||      |.|.| |..|.|.|.|     . .|.|||| ||. ...  . ...          |
--HQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCG

TRGYLAPEWLQS---TITERVDVYSFGIVLLEIVSGQR
.  ..||| | .   ...| .||||||||| ||.....
SFRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase SD21_j-1.AA IRAK 490-706 33 1.3e-45 157.84 In-house 2-233 (317) Show / Hide 
Range on Protein: 490-706
Range on HMM: 2-233/317
Sequence Identity: 33% (79 aa)

NFGKKLGQGGFGSVFLATLNDGS-QVAVKRL---ESSSQGQ--KEFKT---EVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPS
. . ..|.|||| |. . ..     .|||.|   ...|...  ..| .   |. | ....| |.| | |.|.|     |||.|||  ||   |  .|   
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQD---

DGDHEKAGEALDWKTRLRIALGIARGLKYLHDDCSE-RILHLDVKPQNVLLDSNFDAKLCDFGMSKLM---KRNESEVFTMM-----RGTRGYLAPEWLQ
      .  .| | .|. |..|.|.|. .||.. .   | | |.|. |.||| .| .|.||||.         .|. . |.|     |||  |..|| . 
---GQCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIR

---STITERVDVYSFGIVLLEIVSGQRCLGNSRAETST
     .| ..|||||||||||...|.|   . |.|. .
DPQGQLTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYY
Kinase SD21_j-1.AA Dicty4 490-694 35 1e-42 140.41 In-house 2-214 (277) Show / Hide 
Range on Protein: 490-694
Range on HMM: 2-214/277
Sequence Identity: 35% (78 aa)

NFGKKLGQGGFGSVFLATLNDGSQVAVKRL-----ESSSQGQKEFKTEVNVISSIHHFNLVRLRGFCA----EKHHRLLVYEYMPRRSLDKWLFLRDFPS
|.....|.|.||.|...|   |..|||| |      ...   .||. ||.  ..| | |.. . | |     ..   . | ||||. .| .   |.| ||
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYS--LLHDKPS

DGDHEKAGEALDWKTRLR---IALGIARGLKYLHD-DCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVF-TM-MRGTRGYLAPEWLQSTI
.   ..    ||| ...|   .|. .|||. .||  ..  .|.|.| |. | | | |. .| |||| |..||. |.  . .| . || .. ||| ...  
EQQQSI---KLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

-TERVDVYSFGIVLLEIVSGQ
 .| .||||||||| ||. .|
YNEKADVYSFGIVLWEILTRQ
Kinase SD21_j-1.AA MLK 489-694 26 8.6e-37 125.19 In-house 1-233 (291) Show / Hide 
Range on Protein: 489-694
Range on HMM: 1-233/291
Sequence Identity: 26% (62 aa)

NNFGKKLGQGGFGSVFLATLNDGSQ-----VAVKRLE-------SSSQGQKEFKTEVNVISSIHHFN----LVRLRGFCAEK-HHRLLVYEYMPRRSLDK
 .| ...| |.||.|....   .       ||||| .       ...  |..|..|..  . . | |     ....| |..  .| ..| ||..  ||  
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WLFL-RDFPSDGDHEKAGEA----LDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDS------NFDAKLCDFGMSKLMKRNESEVFTMMRG
 |   |. ..|      ..      |    ...|| .|||. ||| .    | | | |..|.|.|       . ..| |||| |. ..... .  . ..|
VLHGARSKWMDAN---HNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAG

TRGYLAPEWL----QSTITERVDVYSFGIVLLEIVSGQ
|  . ||| .     .. .| .||.|.|.|| |.....
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
S_TKc SD21_j-1.AA S_TKc 489-773 20 3e-36 127.65 SMART 1-231 (231) Show / Hide 
Range on Protein: 489-773
Range on HMM: 1-231/231
Sequence Identity: 20% (61 aa)

NNFGKKLGQGGFGSVFLATLND-GSQVAVKRLESSSQGQKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPR--RSLDKWLFLRDFPSDGDHE
  ...|.|.|.||.|.... .. | .||.|..       . .. |... .. || |.|.| ... . .|  .| ||..    .| . .  |  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH------

KAGEALDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQSTITE-RVDVYSFG
. .  ..  .  ...  |...|.|.|   | .|.| |.||.|.|||.    |.||||.....        | . ||. |.||| |    .  ..|..|.|
GLRFPFPE-HARFYMYQICCALEYCH---SHGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL--GYGKCKCDWWSCG

IVLLEIVSGQRCLGNSRAETSTQYFPNWASSRICRGQIMEIADSSLHGELQSGMVALWEQVELVIYTAMWCIQEDSAQRPSMEMVIR---------ML
..| | ..|.                          |.... .  .               . ..   . | | | ..||.   . .          .
CILYEMLCGYPPFP----------------------QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD21_j-1.AA LRRK 489-695 26 9.3e-35 120.39 In-house 1-281 (351) Show / Hide 
Range on Protein: 489-695
Range on HMM: 1-281/351
Sequence Identity: 26% (76 aa)

NNFGKKLGQGGFG-SVFLATLND---------------------------GSQVAVKRLES----------SSQG-------------------------
  .....|.|||| .|. |....                           .. ||.| ..           .| .                         
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPSDG-DHEKAGEALDWKTRLRIALGIARGLKYLHDDCSER--ILHLD
  ||  || ..|. .| |.| | |||   |.. .| ||.|  .|..  ||... .||    |    ..| ..|.||| ||.|..|||   | .  |.| |
FREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYH--FLHNKKQDGFHFMK--AHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRD

VKPQNVLL---D---------SNFDAKLCDFGMSKLMKRNESEVFTMMRGTRGYLAPEWLQ----STITERVDVYSFGIVLLEIVSGQ-R
 |. |.||   .          .  ||..||| | . .   ..|.  . |. |..||| ..    .. || ||.||||..| |....| .
LKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase SD21_j-1.AA Pkinase_Tyr 490-692 28 2e-34 117.24 Pfam 2-209 (270) Show / Hide 
Range on Protein: 490-692
Range on HMM: 2-209/270
Sequence Identity: 28% (63 aa)

NFGKKLGQGGFGSVFLATLN-----DGSQVAVKRL--ESSSQG--QKEFKTEVNVISSI-HHFNLVRLRGFCA-EKHH--RLLVYEYMPRRSLDKWLFLR
 ||||||.| ||.|...|..     .. .|||| |   ....   ...|  |... ... || |.||| | |  .. .   ..| ||||  .|.. |  .
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

DFPSDGDHEKAGEALDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTMMRGTRG---YLAPE-WLQS
           ...|. |. | ... ||.|. ||..     . | |.   |.|...|. .| ||||.....   .   ...  |..     .||| .  .
R--------EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYG

TITERVDVYSFGIVLLEIVS
  |.  ||.|||... ||..
KFTTKSDVWSFGVLMWEIFT
Kinase SD21_j-1.AA TK 489-692 17 2.7e-31 101.59 In-house 1-389 (486) Show / Hide 
Range on Protein: 489-692
Range on HMM: 1-389/486
Sequence Identity: 17% (68 aa)

NNFGKKLGQGGFG---SVFLATLNDGS--------------------------QVAVKRLES-SSQGQKEFKT--------------EVNVISSIH----
  .|||||.| ||    |.........                          .|||| | . ... |.||.               |.....  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HFNLVRLRGFCAEK------------HHRLLVYEYMPRRS----LDKWLFLRDFPSDGDHEKAGEA---------------------------------
 | |.||| | | ..            .. ..| ||||  .    |..  .||. . .. ||  . .                                 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRD--YLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQ

---------------------------------LDWKTRLRIALGIARGLKYLHDD----CSERILHLDVKPQNVLLDSNFD-----------AKLCDFG
                                 |. ...| ... ||.|. |||.        .. | |.   |.|...|             .|..|||
DYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFG

MSK-----LMKRNES--EVFTMMRGTRGY--------------------------LAPEWLQSTI----------TERVDVYSFGIVLLEIVS
.|.     | .. .|  .  ..  ...|                           .||| |.. .          |.  ||.|||... ||..
LSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD21_j-1.AA TK-Unique 489-692 25 1.8e-30 102.38 In-house 1-234 (294) Show / Hide 
Range on Protein: 489-692
Range on HMM: 1-234/294
Sequence Identity: 25% (62 aa)

NNFGKKLGQGGFGSVFLATLNDGS-------QVAVKRLESSSQGQK--EFKTEVNVISSIH-HFNLVRLRGFCAEKH-HRLLVYEYMPRRSLDKWLF-LR
 ..|...|.| || |. ...  ..       .|||| |. ......  .|. | .. ...  | |.|.. | | ..    ....||.|. .|.. |   |
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

DFPSDG-------------DHEKAGEALDWKTRLRIALGIARGLKYLHDDCS--ERILHLDVKPQNVLLDSNFDAKLCDFGMSK-LMKRNESEVFTMM--
. ....              ...  |... |. ...| .||.|..||.   |  ..| | |.   |||| ... .|.|||||.. ...    .|  ||  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLA---SQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYT---NGVYSMMCS

--RGTRGYLAPEWLQ---STI-TERVDVYSFGIVLLEIVS
  |    ..||| |.    .. |.. ||.|||... ||..
QGRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase SD21_j-1.AA DRK 490-691 35 1.8e-30 100.43 In-house 2-196 (258) Show / Hide 
Range on Protein: 490-691
Range on HMM: 2-196/258
Sequence Identity: 35% (74 aa)

NFGKKLGQGGFGSVFLATLNDGSQVAVKRLESSSQG----QKEFKTEVNVISSIHHFNLVRLRGFCAEKHHRLLVYEYMPRRSLDKWLFLRDFPSDGDHE
  |   | |..| ||. |   |.|||||.|           .||. |.|...   | | .   | | .    . . ||||| || . |          |.
KIGNRIGRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNIL----------HD

KAGEALDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRNESEVFTM-MRGTRGYLAPEWLQSTI-TERVDVYSF
 . | .||  ...... .|.|. |||  |   |.| | |  | | | ..  |  ||| |   |. ..  |.| | || .  ||| | .   ||  |||||
ESIE-MDWPLMKQMMFDCAKGMIYLH-CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSF

GIVLLEIV
.||| |.|
AIVLWECV
Kinase SD21_j-1.AA TyrKc 489-773 23 2.7e-28 101.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 489-773
Range on HMM: 1-280/280
Sequence Identity: 23% (73 aa)

NNFGKKLGQGGFGSVFLATLNDGSQVAVKRLESSSQGQKEFKTEVNVISSI--HHFNLVRLRGFCAEK-------HHRLLVYEYMPRRSLDKWL-FLRDF
  .||||| | || |...|..   ||||| | ...  ...|  | .. ...  || |.||| | | ..       .  ..| ||||  .|.. |   |. 
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

PSDGDHEKAGEALDWKTRLRIALGIARGLKYLHDDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKRN-----ESEVFTMMR--GTRG-----YLA
            | .|. | ... ||.|  |||.    .. | |    |.|...|. .| .|||.|.  .       .... ...   |...      .|
------------LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMA

PEWLQSTI-TERVDVYSFGIVLLEIVSGQRCLGNSRAE--TSTQYFPNWASSRICRGQIME---IADSSLHGELQSGMVALWEQVELVIYTAMWCIQEDS
|| ..  . |.  ||.|||... || .         ..   | |   ..  ..  . |  .   ..         .      .  . .     .| .|| 
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------F-----VCCPDEMYQIMKQCWHEDP

AQRPSMEMVIRML
..||... ... .
EDRPTFSEIHECF
Kinase SD21_j-1.AA STE 598-699 25 1.6e-22 76.4 In-house 155-270 (359) Show / Hide 
Range on Protein: 598-699
Range on HMM: 155-270/359
Sequence Identity: 25% (32 aa)

RIALGIARG-LKYLHDDCSERILHLDVKPQNVLLDSNFDAKLCDFGMSKLMKR---------------NESEVFTMMRGTRGYLAPEWLQ-------STI
.|.  | .| |.|||.     | | |.||.|.||     .|||||| .. .                 . ..  . . ||  . ||| .|       .  
YICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGY

TERVDVYSFGIVLLEIVSGQRCLGN
....|..|.|....| . |.  . .
DTKCDIWSLGCTIIEMATGKPPWHD
Kinase SD21_j-1.AA STE 489-571 16 1.6e-11 37.06 In-house 1-126 (359) Show / Hide 
Range on Protein: 489-571
Range on HMM: 1-126/359
Sequence Identity: 16% (21 aa)

NNFGKKLGQGGFGSVFLATLND----------------GSQVAVKRLESSSQG------------------QKEFKTEVNVISSIH--HFNLVRLRGFCA
  . .|.|.|.||.|..|  ..                |  .|.|... ...                   ..... |... .  .  | | |.  | . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EK-------HHRLLVYEYMPRRSLDK
 .       ..  .. |||.  |||.
KEGHNHKNDDELWICMEYMDGGSLDD
Kinase SD21_j-1.AA DRK 755-775 42 0.00018 11.1 In-house 238-258 (258) Show / Hide 
Range on Protein: 755-775
Range on HMM: 238-258/258
Sequence Identity: 42% (9 aa)

CIQEDSAQRPSMEMVIRMLEG
|  ||  .||||. ..  || 
CWNEDPQHRPSMQECLERLEA
Kinase SD21_j-1.AA TK 748-773 22 0.001861 6.6 In-house 460-486 (486) Show / Hide 
Range on Protein: 748-773
Range on HMM: 460-486/486
Sequence Identity: 22% (6 aa)

VIYT-AMWCIQEDSAQRPSMEMVIRML
..|   . | ..| ..||... . ..|
EYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase SD21_j-1.AA MLK 755-773 31 0.005923 6.24 In-house 273-291 (291) Show / Hide 
Range on Protein: 755-773
Range on HMM: 273-291/291
Sequence Identity: 31% (6 aa)

CIQEDSAQRPSMEMVIRML
| ..|...|||. ...  |
CWNQDPHKRPSFRQIVQHL
Kinase SD21_j-1.AA TK-Unique 755-773 31 0.008332 5.65 In-house 276-294 (294) Show / Hide 
Range on Protein: 755-773
Range on HMM: 276-294/294
Sequence Identity: 31% (6 aa)

CIQEDSAQRPSMEMVIRML
|.|..  .||| . .. .|
CWQWEPEERPSFRQIKHRL
Kinase SD21_j-1.AA LRRK 753-775 26 0.069192 2.44 In-house 329-351 (351) Show / Hide 
Range on Protein: 753-775
Range on HMM: 329-351/351
Sequence Identity: 26% (6 aa)

MWCIQEDSAQRPSMEMVIRMLEG
..| |.|  .||... ..  |. 
QHCWQHDPKKRPHFSQIVKRLSQ
Kinase SD21_j-1.AA Pkinase_Tyr 755-773 26 0.106352 6.38 Pfam 252-270 (270) Show / Hide 
Range on Protein: 755-773
Range on HMM: 252-270/270
Sequence Identity: 26% (5 aa)

CIQEDSAQRPSMEMVIRML
| ..| ..||... ....|
CWHYDPEDRPTFSEIHEQL
Kinase SD21_j-1.AA Dicty4 754-775 41 0.213403 0.62 In-house 254-277 (277) Show / Hide 
Range on Protein: 754-775
Range on HMM: 254-277/277
Sequence Identity: 41% (10 aa)

WCIQEDSAQRPSMEMVIRM--LEG
||  .|  .|||.| .|    || 
WCWDHDPQHRPSFEEIIQRRILEH
Kinase SD21_j-1.AA TKL-Unique 755-773 42 0.244439 0.7 In-house 272-290 (290) Show / Hide 
Range on Protein: 755-773
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CIQEDSAQRPSMEMVIRML
|   |. |||| . .|  |
CWHHDPSQRPSFDEIIHRL