WAKc-23_a-2

Species: S.moellendorffii
Alias: WAKc-23_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: WAKc23

Sequence

Name Sequence Type Origin Length Description Download
WAKc-23_a-2.AA Protein None 843 None Fasta, JSON
WAKc-23_a-2.NA RNA None 2532 None Fasta, JSON
WAKc-23_a-2.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of WAKc-23_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin WAKc-23_a-2.AA B_lectin 116-218 31 3.5e-25 88.11 Pfam 1-137 (137) Show / Hide
Range on Protein: 116-218
Range on HMM: 1-137/137
Sequence Identity: 31% (43 aa)

LARIIWEANQD---DPV-----SANATLGFEG-DGGLALRDSG-G-RL--VWTT--G-PLNG--LSTTLELQETGNLTVR-NVD--NEVLWQS--FGSPT
   . | ||.|   .||     . |.|| . . || | | |.| | .   || |  . . .|   ......|..||| .. . .  |.|||||  |. ||
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

DTLVLQQPLSP------GMR----LESRRSSTNSS--S
||.   ..|        .|.    | |..|.|| .  |
DTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTN-YDPS

B_lectin WAKc-23_a-2.AA B_lectin 77-191 23 8.6e-12 46.42 SMART 1-126 (126) Show / Hide
Range on Protein: 77-191
Range on HMM: 1-126/126
Sequence Identity: 23% (30 aa)

GYTAPNLSLLNIAQY--S--LAFVNHSSGLFTLAIVTNSSAGSLARIIWEA--NQDDPVSA---NATLGFEGDGGLALRDSGGRLVWTTGPL-NGLSTTL
 .|  .   |   .   .  | |... .  ... |. ... ..  ...| |  | | ||.    ...| .  || | . |  .| || ..   |   ...
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ-WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNGNYVA

ELQETGNLTVRNVD----NEVLWQSFGSP
.||..||. ... |    ....|||| .|
VLQDDGNFVIYDPDDNDSGNFIWQSFDHP

PAN_AP WAKc-23_a-2.AA PAN_AP 381-455 21 0.000245 21.12 SMART 1-85 (85) Show / Hide
Range on Protein: 381-455
Range on HMM: 1-85/85
Sequence Identity: 21% (19 aa)

SSSLDFVSLPGIEHFSHRY----LNGSSLSFQLCRSQCLQNCSCSAFFFWEESSSCFLMD---SLRTLQ------AVPNHRHVAYVKV
.. ..|| .|...  . .     .   . | . |...||.|||| .| . . ...| |..   .|   .       .|| . . | |.
CCDDCFVRMPNMKL-FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN

Kinase WAKc-23_a-2.AA TKL 547-803 19 2.8e-47 163.4 In-house 1-364 (364) Show / Hide
Range on Protein: 547-803
Range on HMM: 1-364/364
Sequence Identity: 19% (74 aa)

IGTGSFGSVYEGVLPE---------GRKVAVKRLES---TGQGK-------------------------RKIFAEVAVLGTFHHWNLVRLLGFCDQGCHG
|| |.|| || |..           |. ||||.. |       |                          ..  |. ..  ..| |.|...|.| .. .|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------FIIYEHIGNGSLDRWIYRDNGENVLDWELRMGIVMGIARGLAYLHE-------ECMEVHLNLKPQNVLLDSSFV-------------
             .|..| . .|||   .          |..|. ....||||..|||         .  .| .||..|.|.|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKLSGYGVSRIMARESQSSAA-------------------KTGLESYHPPEWLLDT----------------SITEKCDVYSFGILLLEIISGKRSSNS
 .|.. .| || | .......                    . |   . .|| | ..                . .||||||||||.| ||....|    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

DKFYLPAHALD-LTRQGR----QMQLVDT-RIVKDTSESKVR--------QGV-----SIAFQCLQEDPRSRPSMGDVVQML
     | . ..  .....    .|. ..  .  . .  .  .          .     ... .| ..||..|||. .... |
-----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase WAKc-23_a-2.AA TKL-Unique 543-736 25 1.6e-36 126.34 In-house 1-226 (290) Show / Hide
Range on Protein: 543-736
Range on HMM: 1-226/290
Sequence Identity: 25% (59 aa)

FSKLIGTGSFGSVYEGVLPEGRKVAVKRLE-STGQGKRKIF---AEVAVLGTFH-HWNLVRLLGFCD----QGCHGFIIYEHIGNGSLDRWIYR------
|...||.|..|.|| |. . | .||.|...   .. .....    || .. ..| | |.|.. |.|     .  . .|. | .  |||.  . .      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

-DNGENVLDWELRMGIVMGIARGLAYLHEECM-EVHLNLKPQNVLLDSS-----FVPKLSGYGVSRIMARESQSSAA------KTGLE---SYHPPEWLL
  | .. |....|. ..  ||.|. ||| .     |..||..|.|.|.      .  |... | |.. ........       ... .    . .|| | 
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

D--TSITEKCDVYSFGILLLEIISGKR
.  . ..||.||||||| | ||...|.
MNFCQYSEKSDVYSFGIVLWEIATRKI

Kinase WAKc-23_a-2.AA Pkinase 542-803 21 3.1e-29 104.47 Pfam 2-293 (293) Show / Hide
Range on Protein: 542-803
Range on HMM: 2-293/293
Sequence Identity: 21% (64 aa)

NFSKLIGTGSFGSVYEGVLPEGRK-VAVKRLESTGQGKRK---IFA--EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNG----SLDRWIY-RDNG
 . . || ||||.||...    .| ||||...  .. . |    .   |....  ..| | |||....  . |  .. |. ..|    .| ..|  ...|
HIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

ENVLDWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVP----KLSGYGVSRIM-ARESQSSAAKTGLESYHPPEWLL-DTSITEKCDVYSF
   ....    ..  |.|||.|.|. .  .|  |||.|.|.|.  ..    |..  |... .    ..     .|   | .||... .. .. |.|..|.
CFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLLEIISGKRSSNSDKFYLPAHALDLTRQGRQMQLVDTRIVKDTSESKV-----------------------RQGVSIAFQCLQEDPRSRPSMGDVVQ
|..| | ..|.       .  | |  .  .  .|||... .  ......                         . . ..   ||. || .||.  ...|
GCILYEMLCGR-------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

M--L
   .
HPWF

Kinase WAKc-23_a-2.AA IRAK 542-736 31 4.3e-29 100.32 In-house 2-222 (317) Show / Hide
Range on Protein: 542-736
Range on HMM: 2-222/317
Sequence Identity: 31% (70 aa)

NFSKLIGTGSFGSVYEGVLPEGRK--VAVKRLE-----STGQGKRKIFA---EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSL-DRWIYRDNG
. . .|| | || || |..  .    .|||.|      |... ..   .   |. |. ...| |.| |.|.| ..     .|. . |||| ||   .|. 
HKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

ENV--LDWELRMGIVMGIARGLAYLHEEC---MEVHLNLKPQNVLLDSSFVPKLSGYGVSRIM----ARESQSS-AAKTGLES----YHPPEWLL--DTS
     | |  |  |  |.|.|. .||.        | . |. |.|||  |.||..  |  |      ..|.|..  ..| .      | ||| .      
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ITEKCDVYSFGILLLEIISGKR
.| | ||||||| |||...| |
LTKKTDVYSFGIVLLEVLTGCR

Kinase WAKc-23_a-2.AA TK 541-733 16 6.2e-27 86.69 In-house 1-389 (486) Show / Hide
Range on Protein: 541-733
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

DNFSKLIGTGSFG---SVYEGVLPEGR--------------------------KVAVKRLEST-GQGKRKIFA--------------EVAVLGTFH----
  . | .| | ||    ||.| . ...                          .|||| | .. .. ..  |.              |....  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HWNLVRLLGFCDQGC------------HGFIIYEHIGNGS----LDRWIY--RDNGEN-----------------------------------------
 | |.|||.| | ||             .  |. |.  .|.    |. .    |... .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------VLDWELRMGIVMGIARGLAYLHEE-C----MEVHLNLKPQNVLLDSSFV-----------PKLSGYGVSR
                               |. . .. . . ||.|..|||.  |      || .|   |.|.... |            |.. .| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

I----MARESQSSAAKTGLESY------------------------------HPPEWLLDTS---------ITEKCDVYSFGILLLEIIS
     .||. .|.   .  .||                               .|| |.|            |.| ||.|||.|. || .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT

Kinase WAKc-23_a-2.AA LRRK 542-736 20 3.9e-24 82.27 In-house 2-281 (351) Show / Hide
Range on Protein: 542-736
Range on HMM: 2-281/351
Sequence Identity: 20% (59 aa)

NFSKLIGTGSFG-SVYEGVLPE---------------------------GRKVAVKRLEST-------------------------------GQGKRKIF
 . ..|| |.|| .|| . .                             . .||.| .. .                               .... ..|
KIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAF

A----EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIYRDNGEN------VLDWELRMGIVMGIARGLAYLHEEC-MEVHLNLKPQNVLL
     ||... ...| |.| |.||| .  .  .. | . .|.|.. .             ...| |.  |.. ||.|..|||    . .| .||. |.||
REFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DSS------------FVPKLSGYGVSRIMARESQSSA-AKTGL--ESYHPPEWLLDT---SITEKCDVYSFGILLLEIISGK-R
 ||             . |.. .| || |   .  .. ||. .  . .. || . ..   . ||| |.||||..| |..... .
WSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH

Kinase WAKc-23_a-2.AA Src-Echino1 542-735 30 2.5e-22 73.9 In-house 2-195 (252) Show / Hide
Range on Protein: 542-735
Range on HMM: 2-195/252
Sequence Identity: 30% (61 aa)

NFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIYRDNGENVLDWELRMG
 . | || | .| |..||     .|||| |      . .  ||  |. .  | ..|..   |      .|. | . ||.|  .. |... .|    .   
RMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHV---KMTTL

IVMG--IARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARES--QSSAAKTGLESYHPPEWLLDTSITEKCDVYSFGILLLEIIS-GK
| ||  || |. || .  . || .|  .|||..   | |.  .|  |.| ..       ||  .  .  ||  |  . | | ||.|||||. |..  |.
IDMGAHIASGMDYLGSKNV-VHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIK-WTAPEAALYGRFTIKSDVWSFGILMTEMVTFGR

Kinase WAKc-23_a-2.AA S_TKc 541-803 21 3.2e-22 81.08 SMART 1-231 (231) Show / Hide
Range on Protein: 541-803
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

DNFSKLIGTGSFGSVYEGVLPE-GRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGN--GSLDRWIYRDNGENV---L
  . ..|| |.||.|| ..  . ||.||.|..       ..|  |...|   || |.|.|.....   | ... |....  |.| . | . ...     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARESQSSAAKTGLESYHPPEWLLDTSITE-KCDVYSFGILLLEIIS
.      ..  |...|.|.|.    .|  |||.|.|||.  . |..  |..|..           |   | .|| |   . .  |||..|.|..| | ..
PE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GKRSSNSDKFYLPAHALDLTRQGRQMQLVDTRIVKDTSESKVRQGVSIAFQCLQEDPRSRPSMGDVVQ---------ML
|.          ..  ... .                     ... ..  .||| ||. ||.  .. |          .
GYPPFP-----QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase WAKc-23_a-2.AA Frk 542-732 27 5.3e-22 72.75 In-house 2-196 (260) Show / Hide
Range on Protein: 542-732
Range on HMM: 2-196/260
Sequence Identity: 27% (55 aa)

NFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIY--RDNGENVLDWELR
 . . .|.| || |.||       ||||.| .     .   .|  ..    |  |..|   |      .|| | . .|||  ..    |.|.. .  .  
QLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ-CQMQQL

MGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARESQ-SSAAKTGLE---SYHPPEWLLDTSITEKCDVYSFGILLLEII
. .   .| |.||| |.   .|  |   |||.. . . |.  .|. |.. .. .    ...|      .  ||     . | | ||.|||||| |||
VDMAAQVAAGMAYL-ESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEII

Kinase WAKc-23_a-2.AA TK-Unique 542-733 24 1.2e-21 71.51 In-house 2-234 (294) Show / Hide
Range on Protein: 542-733
Range on HMM: 2-234/294
Sequence Identity: 24% (57 aa)

NFSKLIGTGSFGSVYEGVLPE-------GRKVAVKRLE--STGQGKRKIFAEVAVLGTFH-HWNLVRLLGFCDQGC-HGFIIYEHIGNGSLDRWIY--RD
.. ..||.|.|| |. | . .        ..|||| |.  .|.. |.. . | ...     | |.|..|| |       .||.|.. .|.|.  .   |.
EVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRP

N-----------------GENVLDWELR----MGIVMGIARGLAYLHE-ECMEVHLNLKPQNVLLDSSFVPKLSGYGVSR-IMARESQSSAAK--TGLES
.                  . ... ..       .  .||.|..||..  .. || .|   |||| . .| |....| .| ..... .|.  .  .    
AMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIR

YHPPEWLL--DTSI-TEKCDVYSFGILLLEIIS
. .|| |.  .  . |.| ||.|||.|. || .
WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT

Kinase WAKc-23_a-2.AA STE 543-735 19 1.3e-21 73.11 In-house 1-265 (359) Show / Hide
Range on Protein: 543-735
Range on HMM: 1-265/359
Sequence Identity: 19% (54 aa)

FSK--LIGTGSFGSVYEGVLPE----------------GRKVAVKRLESTGQG------------------KRKIFAEVAVLGTFH--HWNLVRLLGFCD
. .   || |.||.|| ..  .                |. .|.|...   .                   . .|  |. ..  ..  | | |. .| . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QGC-------HGFIIYEHIGNGSLDRWIY---RDNG-------------ENVLDWELRMGIVMGIARG-LAYLHEECMEVHLNLKPQNVLLDSSFVPKLS
...       . .|. |....||||  |      ..             |... .     |.  | .| |.|||.    .|  .||.|.||      ||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY-----ICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLC

GYGVSRIMARE----------------SQSSAAKTGLESYHPPEWLL------DTSITEKCDVYSFGILLLEIISGK
  ||. ... .                .| .   .|   .  || ..      |   ..|||..|.|....| . ||
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase WAKc-23_a-2.AA Pkinase_Tyr 542-655 27 9.3e-21 70.92 Pfam 2-129 (270) Show / Hide
Range on Protein: 542-655
Range on HMM: 2-129/270
Sequence Identity: 27% (35 aa)

NFSKLIGTGSFGSVYEGVLP-----EGRKVAVKRL--ESTGQG--KRKIFAEVAVLGTF-HHWNLVRLLGFCD-QGCH--GFIIYEHIGNGSLDRWIYRD
 | | .| |.||.||.|..      .. .|||| |   .. .   ... ..|.... .. || |.|||.| |  || .   .|. |.  .|.|.    . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

-NGENVLDWELRMGIVMGIARGLAYLHE
 .... |. .   .. . ||.|..||..
REDKQPLTMKDLLQMCWQIAKGMEYLES

Kinase WAKc-23_a-2.AA MLK 542-672 27 3.4e-19 63.34 In-house 2-161 (291) Show / Hide
Range on Protein: 542-672
Range on HMM: 2-161/291
Sequence Identity: 27% (44 aa)

NFSKLIGTGSFGSVYEGVLPEGRK-----VAVKRLE-------STGQGKRKIFAEVAVLGTFHHWN----LVRLLGFCDQ-GCHGFIIYEHIGNGSLDRW
.|.. || ||||.|. |.   ..      ||||| .       .|.  ....  |.  |  . | |     ....| | | .|| .|. | . .||| . 
QFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IYRD--------NGEN---VLDWELRMGIVMGIARGLAYLHEECME--VHLNLKPQNVLLD
..          ....   | | .. | . . .|||..|||..     .|  ||..|.|.|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILID

Kinase WAKc-23_a-2.AA TyrKc 541-803 23 1.5e-17 60.86 SMART 1-280 (280) Show / Hide
Range on Protein: 541-803
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

DNFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTF--HHWNLVRLLGFCDQG-------CHGFIIYEHIGNGSLDRWI--YRDN
  . | .| | || ||.|..   ..|||| | .    .. .  |  ..  .  || |.|||.| | |.          .|. |.  .|.|.  .  .|..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

GENVLDWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARE------SQSSAAKT--GLES-----YHPPEWLLDTSIT
    | ..    .   ||.| .|||. .  .|  |   |.|... .. | |  | ||    .      ..   .|.  |  .       .|| . .   |
----LCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKCDVYSFGILLLEIISGKRSSNSD---KFYLPAHALDLTRQGRQMQLVDT-----RIVKDTSESKVRQGVSIAFQCLQEDPRSRPSMGDVVQML
.| ||.|||... || .   .  ..   ..  ..... . .||. |   .        |  ..|       .|  || .||| .||.. .... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEM-----YQIMKQCWHEDPEDRPTFSEIHECF

Kinase WAKc-23_a-2.AA MLK 716-735 45 4e-06 17.36 In-house 214-233 (291) Show / Hide
Range on Protein: 716-735
Range on HMM: 214-233/291
Sequence Identity: 45% (9 aa)

TEKCDVYSFGILLLEIISGK
.|||||.|.|..| |.....
SEKCDVWSWGVVLWEMLTRE

Kinase WAKc-23_a-2.AA TK 784-803 35 8e-06 14.75 In-house 467-486 (486) Show / Hide
Range on Protein: 784-803
Range on HMM: 467-486/486
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||. ||.. .....|
QCWHYDPEDRPTFSQLHEQL

Kinase WAKc-23_a-2.AA MLK 784-803 50 9e-06 16.13 In-house 272-291 (291) Show / Hide
Range on Protein: 784-803
Range on HMM: 272-291/291
Sequence Identity: 50% (10 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||..|||.  .|| |
QCWNQDPHKRPSFRQIVQHL

Kinase WAKc-23_a-2.AA TK-Unique 784-803 35 0.000207 11.26 In-house 275-294 (294) Show / Hide
Range on Protein: 784-803
Range on HMM: 275-294/294
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
.|.|..| .|||  .....|
SCWQWEPEERPSFRQIKHRL

Kinase WAKc-23_a-2.AA LRRK 784-805 36 0.000215 11.44 In-house 330-351 (351) Show / Hide
Range on Protein: 784-805
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

QCLQEDPRSRPSMGDVVQMLQG
.| |.||..||.. ..|. |  
HCWQHDPKKRPHFSQIVKRLSQ

Kinase WAKc-23_a-2.AA Pkinase_Tyr 706-733 42 0.001081 13.13 Pfam 182-209 (270) Show / Hide
Range on Protein: 706-733
Range on HMM: 182-209/270
Sequence Identity: 42% (12 aa)

PPEWLLDTSITEKCDVYSFGILLLEIIS
.|| . .   |.| ||.|||.|. ||..
APECINYGKFTTKSDVWSFGVLMWEIFT

Kinase WAKc-23_a-2.AA Pkinase_Tyr 784-803 35 0.001518 12.63 Pfam 251-270 (270) Show / Hide
Range on Protein: 784-803
Range on HMM: 251-270/270
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||  ||.. .....|
QCWHYDPEDRPTFSEIHEQL

Kinase WAKc-23_a-2.AA TKL-Unique 784-803 40 0.060346 2.87 In-house 271-290 (290) Show / Hide
Range on Protein: 784-803
Range on HMM: 271-290/290
Sequence Identity: 40% (8 aa)

QCLQEDPRSRPSMGDVVQML
||   ||  |||  ...  |
QCWHHDPSQRPSFDEIIHRL

Kinase WAKc-23_a-2.AA IRAK 780-803 29 0.316901 0.3 In-house 294-317 (317) Show / Hide
Range on Protein: 780-803
Range on HMM: 294-317/317
Sequence Identity: 29% (7 aa)

SIAFQCLQEDPRSRPSMGDVVQML
. | .|. .  . |..|  |.| |
QCACCCGHHRANRRCDMAWVMQQL