Gene MLK-p1_d-2 (S.moellendorffii)

MLK-p1_d-2

Species: S.moellendorffii
Alias: MLK-p1_d-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLK-plant1

Sequence

Name Sequence Type Origin Length Description Download
MLK-p1_d-2.AA Protein None 939 None Fasta, JSON
MLK-p1_d-2.NA RNA None 2820 None Fasta, JSON
MLK-p1_d-2.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of MLK-p1_d-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLK-p1_d-2.AA Dicty4 661-915 48 2.3e-134 450.39 In-house 1-277 (277) Show / Hide 
Range on Protein: 661-915
Range on HMM: 1-277/277
Sequence Identity: 48% (134 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKF--LNQDISGDALEEFITEVRLMRRMRHPNVVLFMGAVT----RPPNLSIVTEFLPRGSLFKLIHR-----
. ...||| ||.||||.| | |.|||.||.  .||. . . |.||  || .|   ||||..||||| |     |. ..||||..|.|.|..|.|      
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-PSNQVD--ERRR-LRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSR-MKHHTFLSS--KSQAGTPEWMAPEVLRNEPSNEKSDV
 .| . |   ..| .|||.|.|.|||.||...| |.|||||| ||||||||.|||||||||. || |. ..   ....||| ||||||....| |||.||
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

YSFGVILWELATLQQPWH--GMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDS--LRP
|||| .|||..| | |    .|. ||.| ||.    |. ||.. .| ... ||.||..||  |||| ||     |  
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLK-p1_d-2.AA DRK 661-915 46 2.5e-119 402.76 In-house 1-258 (258) Show / Hide 
Range on Protein: 661-915
Range on HMM: 1-258/258
Sequence Identity: 46% (121 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDIS-GDALEEFITEVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPSNQVDERRR
  .| ||| |.||||.|| | ||.||.|.  |  |   . | ||  |. || . ||||...|||. . ||   |..|..||||| .  | .| . |  ..
IKIGNRIGRGNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLM

LRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSR----MKHHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELATL
..|..|.||||.|||...| |.|||||| ||||| .| ||| |||||     .| |.|   .   ||| | |||||||..  || |||||...|||..| 
KQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKF--AMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTR

QQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSLRP
| |  ||. .||| .||    |. .|.   |  .. ...||. ||  |||. |..  |  
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase MLK-p1_d-2.AA TKL 667-913 31 3.1e-111 375.83 In-house 1-364 (364) Show / Hide 
Range on Protein: 667-913
Range on HMM: 1-364/364
Sequence Identity: 31% (117 aa)

IGLGSYGEVYRGEWHG----------TEVAIKKFLNQDISGDAL-------------------------EEFITEVRLMRRMRHPNVVLFMGAVTRPPN-
|| |..||||.|.|.|          ..||.|||  .. . . .                         .... |...|.| ||||.|.|||....||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LSIVTEFLPRGSLFKLIHRPSNQVDERRRLRMALDVAKGMNYLHSST------PMIVHRDLKSPNLLVDKNWV--------------V
            | ||.|. |.|||. ..|         .|.|.|||.|.|||||||..      | |.||||||.|.|||.||               .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVCDFGLSRMKHHTFLSSKS-------------------QAGTPEWMAPEVLRNE----------------PSNEKSDVYSFGVILWELATLQQPWHGMN
|.|||||||...... ....                   | ||| ||||||||..                . .||.||||||..|||..| ..|.....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

SMQVV---------GAVGFQNRRLDIP------------ADMDPAIAKIIQECWENDPALRPSFHEIMDSL
.|...           |.  ..|. ||             |..| ..|..|.||. ||  |||| ||.. |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLK-p1_d-2.AA TKL-Unique 663-913 40 1e-109 370.84 In-house 1-290 (290) Show / Hide 
Range on Protein: 663-913
Range on HMM: 1-290/290
Sequence Identity: 40% (116 aa)

VGDRIGLGSYGEVYRGEWHGTEVAIKKFL-NQDISGDALEEFITEVRLMRRMR-HPNVVLFMGAVT----RPPNLSIVTEFLPRGSLFKLIH--------
..  || |.||.||.|.|.|..||||.|  | |.| . ..||. ||..| . . |||.|..||. .     |||..||.|..|.||| ...|        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

-RPSNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKN-----WVVKVCDFGLSRMKHHT---FLSSK------SQAGTPEWMAPEVLRN
 ....  .  .|..||.|.|.||.|||.. | | ||||||.|.||| |     | .|.||||||. .      ... .      .  |.. ||||||||.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--EPSNEKSDVYSFGVILWELATLQQ------PWHGMNSMQVVGAVGF--QNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSL
  .  .|||||||||..|||.|| ..      | .||.. |.  .| .   | |. || .. . . ..||.||  ||  |||| ||  .|
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLK-p1_d-2.AA MLK 661-913 34 1.9e-96 326.73 In-house 1-291 (291) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-291/291
Sequence Identity: 34% (100 aa)

LRVGDRIGLGSYGEVYRGEWHGTE-----VAIKKFL---NQDISGDA--LEEFITEVRLMRRMRHPN----VVLFMGAVTRPPN-LSIVTEFLPRGSLFK
...   || ||.|.|..|.|....     ||.|..      |.|      ..| .|.|. |...|||    .. |.|. ..||. . ||.|... |||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

LIHRPSN-------------QVDERRRLRMALDVAKGMNYLHSSTP-MIVHRDLKSPNLLVD------KNWVVKVCDFGLSRMKHHTFLS-SKSQAGTPE
..|  ..              .|    .. ||..|.||.||||  | .|.||||||.|.|.|      .. ..|.||||.||..|..  .   |.|||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

WMAPEVL---RNEPSNEKSDVYSFGVILWELATLQQPWH-GMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSL
||||||.   |.|. .||.||.|.||.|||. | . | . ....|..   |.  . |. || . .. ..| ...||. ||. |||| .|.  |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLK-p1_d-2.AA Shk 661-913 45 3.3e-94 319.3 In-house 1-264 (269) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-264/269
Sequence Identity: 45% (119 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGDALEEFITEVRLMRRMRHPNVVLFMGAVT-RPPNLSIVTEFLPRGSLFKLIHRPSNQVD--ER
    | .| ||.| || |   | |||.|. . |  .   . .|  || .| . .|||..||||| |  |  ..||||  |.|.| ||.| .  . .    
INREDFLGQGSFGKVYKGRCRGKEVAVKVMHKQNFDENTMTSFRKEVHIMSKIFHPNICLFMGACTSQPGKCMIVTELMPKGNLEKLLHDQMVKKPFILY

RR-LRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSR-MKHHTFLSS--KSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVILWELA
.| .||..| | ||| ||.| . |.|||||. |||||.||.|||||||.|  || |. |.   |...||| ||||||. | | |||.|||||| ||||..
KRAMRMCRDAALGMNWLHGSNCNIIHRDLKTANLLVDQNWRVKVCDFGFSQYMKKHEMLKDKQKGAKGTPLWMAPEVMMNHPYNEKADVYSFGIILWEIL

TLQQPWH--GMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDS--L
| | |      .  . . |.     |  ||.|  .   . || ||  .|  |||| ||     |
TCQEPYPKHHSEYDKFYEAICNKKERPPIPDDCPKSLKHLIQKCWDHNPQRRPSFNEIIQRRIL
Kinase MLK-p1_d-2.AA Pkinase_Tyr 661-913 32 7.5e-76 257.51 Pfam 1-270 (270) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-270/270
Sequence Identity: 32% (89 aa)

LRVGDRIGLGSYGEVYRGEWH------GTEVAIKKFLNQDISGDA--LEEFITEVRLMRRM-RHPNVVLFMGAVT--RPP-NLSIVTEFLPRGSLFKLIH
.. |  .| |..||||.|.|.      ...||.|.  ... . ..  .|.|. |...|. . .|||.| ..|..|  . | .. ||.|. | |.| .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

RP---SNQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTFLSSKS-QAGT-----PEWMAPEVLRNEPSNEK
..    ....  . | |....||||.||.|    ..||||   | ||..| |||.|||||.|     .  .   ....       |||||....   ..|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN--CIHRDLAARNCLVTENNVVKICDFGLARDI---YNDDYYYRKRGGGKLPIKWMAPECINYGKFTTK

SDVYSFGVILWELATL-QQP-WHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSL
|||.|||| .||. |. .|| . ||   .|. ... ...|...| .  . | .....||. ||. ||.| ||   |
SDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLK-p1_d-2.AA LRRK 661-915 29 1.3e-74 254.16 In-house 1-351 (351) Show / Hide 
Range on Protein: 661-915
Range on HMM: 1-351/351
Sequence Identity: 29% (105 aa)

LRVGDRIGLGSYG-EVYRGEWHG----------------------------TEVAIKKFLNQ---------DISG-----------------------DA
|. .  || |..| .|||..| |                            ..|||||..           . ..                        |
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LEEFITEVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPS-NQ------V-DERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLL
. ||  || .|....|||.|  .|   .|  | .|.|..| |.| ...| .. ..      . .   .|. ||..||||.||||..|.|.|||||||| |
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNIL

V---D---------KNWVVKVCDFGLSRMKHHTFLS--SKSQAGTPEWMAPEVLR---NEPSNEKSDVYSFGVILWELATLQ-QPWHGMN-------SMQ
.   .          . ..|..|||.|||   .|..   |   |.| |||||..|   .|  .||.|.||||.||||| |.| .|  ...         |
LWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQ

VVGAVGFQNRRLDIPAD-MDP-----AIAKIIQECWENDPALRPSFHEIMDSLRP
.  ..    .|  || . . |        . ||.||..||  ||.| .| . |  
IEDKI-IEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLK-p1_d-2.AA Dicty4-Unclassified 661-913 36 1.6e-73 250.59 In-house 1-263 (263) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-263/263
Sequence Identity: 36% (96 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGD--ALEEFITEVRLMRRMRHPNVVLFMGAVTRP----PNLSIVTEFLPRGSLFKLIH-RPSNQ
...   || |   .|..| | | .||.|||     .     ...|  || ..  . ||| |   |.   |      . ||.||...| || .|| .|| |
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

-----VDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVLRNEPSNEKSDVYSFGVI
      |.   ...|.|.|.|| .||.    ..|||.|| |.|.||.  .|. |||.||    .|      |||| | .||.|. |  | ||||||....
QQPIKLDDTLIIKYAFDIAQGMQHLHTRN--FIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMT-TIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWELATLQQPWHGMN-SMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSL
|.||||   |. .    | .   |     |  ||   |. . | |  || |||  ||.. .| . |
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase MLK-p1_d-2.AA TKL-ciliate2 661-914 37 3e-72 240.38 In-house 1-273 (273) Show / Hide 
Range on Protein: 661-914
Range on HMM: 1-273/273
Sequence Identity: 37% (104 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGDALEEFITEVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLFKLIHRPSNQVDERRRL
| .  .|  | || .|.  |  . ||.|||  .    . . .|. |   |  .||||.|.|.|| |. || .|. |.  ||||. |.   . ..    | 
LEIQNKITEGGYGIIYKAKWREIVVAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLTWEDRR

RMALDVAKGMNYLHSSTPMIVHRDLK--------------------SPNLLVDKNWVVKVCDFGLSRMK-HHTFLSSKSQAGTPEWMAPEVLRNEPSNEK
|.|||.|.|. ||||| | |.|||||                    | |.||| |   |. |||  |.|    ..  |   ||  ||||||..     ||
RIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNK--IGTYQWMAPEVIKAFYYTEK

SDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMDSLR
 ||.|...||||.|    |. ..    |   |  .| |  || .  | .| ..| ||.|.  ||||| ||.  | 
ADVFSYSIILWEIASREPPYRNKKGDVVAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase MLK-p1_d-2.AA Pkinase 661-913 25 6.4e-72 250.03 Pfam 1-293 (293) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LRVGDRIGLGSYGEVYRGEWHGTE--VAIKKFLNQDISGDALEEFIT--EVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPRG----SLFKLIH-RPS
...| .|| ||.|.||.. ..||.  ||.|..  .... . ... .   |...|.|..|||.| . ......... .|.|... |    .|| .|. . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NQV--DERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVV----KVCDFGLSRMK-HHTFLSSKSQAGTPEWMAPEVLR-NEPSNEKSDVY
. .  .|.   .... ...|..|.||    |.|||||. |.|.|.| ..    |.|||||.. . .      .. .|||..|||||.| ...   |.|..
GCFYFSEWECKFYMYQILRGLEYCHSM--GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGVILWELATLQQPWHGM------NSMQVVGAVGFQNRRLDIPADMD-------------------PAIAKIIQECWENDPALRPSFHEIMDS--L
|.|.||.|... . |. |       . ||..  ..    . |.| . .                   ..  ..|  |.. ||. ||....|. .  .
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase MLK-p1_d-2.AA TyrKc 661-913 31 6.7e-70 239.46 SMART 1-280 (280) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-280/280
Sequence Identity: 31% (90 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKKFLNQDISGDALEEFITEVRLMRRM--RHPNVVLFMGAVTRP-------PNLSIVTEFLPRGSLFKLIHRPS
.. |. .| | .||||.|.|  ..||.|.  .       .|.|. | |.|..   .|||.| . |..| .       . | ||.|. | |.| . .... 
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

NQVDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHT-FL----SSKSQAG--TPE------WMAPEVLRNEPSNE
...  .  | .....|.||.||||    ..||||   | ||..| .||..||||||  ..        . .....           |||||...    ..
PKLCMKDLLSFCWQIACGMEYLHSK--NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KSDVYSFGVILWELATL-QQPWHG-----MNSMQVVGAVGFQNRRLDIPAD--------MDPAIAKIIQECWENDPALRPSFHEIMDSL
||||.|||| .||. |. |||. |     |.  .|.  |  | .|...|..        . ... .|...||. ||. ||.| || . .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVK-QGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLK-p1_d-2.AA CZAK 661-913 36 1.7e-66 227.23 In-house 1-279 (279) Show / Hide 
Range on Protein: 661-913
Range on HMM: 1-279/279
Sequence Identity: 36% (101 aa)

LRVGDRIGLGSYGEVYRGEWHGTEVAIKK-FLNQ--DISG-DALEEFITEVRLMRRMRHPNVVLFMGAVTRPP--NLSIVTEFLPRGSLFKLIHRPSNQV
| .|  || | .||||.. | |. ||||. ..||  . ..   .. |  ||  |   .|||.| |.|| .       .||.|.   ||| .|    .. .
LKFGQTIGQGFFGEVYKAYWRGKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

DE--RRRLRMALDVAKGMNYLHS-STP-MIVHRDLKSPNLLVDKNWV-------------VKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVLRNEPSN
      .. ||.|.|.||||||   .|  |.|||| | | | | .                |. |||||| .        .  |   |||||.   |   
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENYT

EKSDVYSFGVILWELATLQQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIA---KIIQECWENDPALRPSFHEIMDSL
||.|||||| |||.. |  ||  .|  |       . | |. .|  |||      ..|  ||.  | .|||| .|.. |
EKVDVYSFGMILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase MLK-p1_d-2.AA S_TKc 661-921 25 3.5e-63 217.15 SMART 1-231 (231) Show / Hide 
Range on Protein: 661-921
Range on HMM: 1-231/231
Sequence Identity: 25% (70 aa)

LRVGDRIGLGSYGEVYRGEWHG--TEVAIKKFLNQDISGDALEEFITEVRLMRRMRHPNVVLFMGAVTRPPNLSIVTEFLPR--GSLFKLIHRPSNQ---
 .... || |..|.||.. ...   .||||.           | .. |...... .|||.| . ..     .| .|.|...   |.||..|..   .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--VDERRRLRMALDVAKGMNYLHSSTPMIVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTFLSSKSQAGTPEWMAPEVLRNEPSNE-KSDVYSFGVILW
   .| .  ...  ......|.||    |.|||||  |.|.|.  ..|.|||||.|         ... |||..||||||   . .  |.|..|.|.||.
FPFPE-HARFYMYQICCALEYCHSH--GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELATLQQPWHGMNSMQVVGAVGFQNRRLDIPADMDPAIAKIIQECWENDPALRPSFHEIMD-SLRPFQRPVI
|... . |..  . ...   .|            .|    .|. |.. ||. ||.  |..   .   . | .
EMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF