Gene LmjF03.0780 (L.major)
LmjF03.0780
Species: L.major
Alias: LmjF03.0780, LmajK001
External Links:
Annotation:
Group:
AGC
Family:
AGC-Unique
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF03.0780.AA | Protein | None | 3112 | None | Fasta, JSON |
| LmjF03.0780.kin_dom | Protein Kinase Domain | None | 1263 | None | Fasta, JSON |
Protein domains of LmjF03.0780.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | LmjF03.0780.AA | Ciliate-E2 | 248-1158 | 6 | 5.3e-53 | 180.26 | In-house | 1-288 (365) | Show / Hide |
Range on Protein: 248-1158
Range on HMM: 1-288/365
Sequence Identity: 6% (60 aa)
YELIAFLGSGTFAEVTLARN-----------------------KVTGEYFAVKKISKQRVKEEGCVERTF----------TERQLLAKLHHTFLVRLYQA
|..| .|.|.|. | .... ||.. ..|.| ..|. ... ... . |...| .| | .....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC
FQ--SQTHLYLVLDFAQGGDLYS------------LNVQQLWLRSMKRNLVKMQYPYYQSTSRTFTPAPPPAAATSNAQQHQPRASPVSARADGAQRTAG
|| .....|||....|||||.. ..
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE---------------------------------------------------------------
PALPRLPSSATVTQPTEVVPDVQRQQPRGSSGTATSDRDAILASSAMVGSVGPSTVSSASRPGNTVANTATGAALPLPSARDGRASGVADGAHEAAAAVA
----------------------------------------------------------------------------------------------------
VEEEMKEEDAKTTEFDGATDNHHSMAEAPQSAVLQRQRQSIRHAQPGAADCPSQHPRLETDLFYYTTDAIDEFSTSRNVGSGGSRSSPTTPTISRTPEAT
----------------------------------------------------------------------------------------------------
ESATTNAAAAAGDSAPAATRDGEVASSTASVASSGRERYRLLRRRTLPAVERDSGARGGLSVSSSSSSSTADDNSKGRRRRDTADKDGRGSSADSARRLS
----------------------------------------------------------------------------------------------------
WRPRGVACTGPATQAEAASQHPPSPAASTPSRQTAASSASGVSTATSNTALPLATRPSDLTTTDLATPKTQVPLPRSPVHFQCDERSSSSGHSNNGGGGV
----------------------------------------------------------------------------------------------------
DEALRDDESSSAVSVKSTPSLTATKWRPMPRRASASELTDIFAVAASSAAVTVSATSAAGGTSAADVKRYKTTKSAWPPATGAEQPQLASDNSHTATSAT
----------------------------------------------------------------------------------------------------
SAAATSLPRRQKGKAKVVSDKDEGSGASPPLHAGSRHSHRRAPAKKATESHDASEAAADQRSLSTDITTDAAKPLSATVTTMSFVGATAVQDAAATTAAL
----------------------------------------------------------------------------------------------------
RVDLAAPFHQVAMEGSASVLRTLPSTVFAPDGAHRLPLRLIAFYAIEVAL---------------VLQYLHREG-FLYRDLKPENILMCRDGHVMLTDFG
. ... .. |... ... |.||| .. ..||.||||||. . ..|||
-----------------------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFG
VAKYRK------------GAAIMPSGSGEGVQGEVASSPSSSAGACTY----GRANSFTGTTQYMSPEMLRGQP---------HDSRTDWWSYGCLLFE
.|. . . . .. .. .| . .|.. || ||.||.|.|.. .| |.|| |..|.|
LSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD-----------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE
|
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| Kinase | LmjF03.0780.AA | AGC | 1035-1185 | 25 | 2.5e-46 | 116.63 | In-house | 142-340 (395) | Show / Hide |
Range on Protein: 1035-1185
Range on HMM: 142-340/395
Sequence Identity: 25% (55 aa)
RLPLRLIAFYAIE-------VALVLQYLHR-EGFLYRD-LKPENILMCRDGHVMLTDFGVAKY--RKGAAIMPSGS---------GEGVQGEVASSPSSS
|.. . ||| | ..| |.|||. |. .|| |||||||. .|||..||||| .| ..| .. . .. | .
RFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFGLCKEGMNDGEKGQQ-SQSNMKFHWHNKKY-Q-KS-------
AGACTYG----------------------------RANSFTG--TTQYMSPEMLRGQPHDSRTDWWS--YGCLLFEWANGRKAFNTQN----------QF
. |...| | | .||.||.| .. |||| .|||..| |. |. .| ..
------NMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPM
ALFRSIV------EEDVKI
.| .| ...||.
EMFQKIMNGRYFINWKVKF
|
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| Kinase | LmjF03.0780.AA | Ciliate-E2-Unclassified | 248-1158 | 6 | 2.6e-45 | 155.15 | In-house | 1-262 (352) | Show / Hide |
Range on Protein: 248-1158
Range on HMM: 1-262/352
Sequence Identity: 6% (62 aa)
YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVER---------TFTERQ-------------LLAKLHHTFLVRLYQAFQSQTHLYLVL
|..| .|.| |..| ....| ...|.| | ..|.... ... . ... .| . | |.|... .||.. ..|.|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM
DFAQGGDLYSLNV----QQLWLRSMKRNLVKMQYPYYQSTSRTFTPAPPPAAATSNAQQHQPRASPVSARADGAQRTAGPALPRLPSSATVTQPTEVVPD
....|||| |.
EYCEGGDLWQYIKKRKKQK---------------------------------------------------------------------------------
VQRQQPRGSSGTATSDRDAILASSAMVGSVGPSTVSSASRPGNTVANTATGAALPLPSARDGRASGVADGAHEAAAAVAVEEEMKEEDAKTTEFDGATDN
----------------------------------------------------------------------------------------------------
HHSMAEAPQSAVLQRQRQSIRHAQPGAADCPSQHPRLETDLFYYTTDAIDEFSTSRNVGSGGSRSSPTTPTISRTPEATESATTNAAAAAGDSAPAATRD
----------------------------------------------------------------------------------------------------
GEVASSTASVASSGRERYRLLRRRTLPAVERDSGARGGLSVSSSSSSSTADDNSKGRRRRDTADKDGRGSSADSARRLSWRPRGVACTGPATQAEAASQH
----------------------------------------------------------------------------------------------------
PPSPAASTPSRQTAASSASGVSTATSNTALPLATRPSDLTTTDLATPKTQVPLPRSPVHFQCDERSSSSGHSNNGGGGVDEALRDDESSSAVSVKSTPSL
----------------------------------------------------------------------------------------------------
TATKWRPMPRRASASELTDIFAVAASSAAVTVSATSAAGGTSAADVKRYKTTKSAWPPATGAEQPQLASDNSHTATSATSAAATSLPRRQKGKAKVVSDK
----------------------------------------------------------------------------------------------------
DEGSGASPPLHAGSRHSHRRAPAKKATESHDASEAAADQRSLSTDITTDAAKPLSATVTTMSFVGATAVQDAAATTAALRVDLAAPFHQVAMEGSASVLR
|.
----------------------------------------------------------------------------------------QK----------
TLPSTVFAPDGA---------HRLPLRLIA-----FYAIEVALVLQYLHREG-FLYRDLKPENILMCRDG---HVMLTDFGVAK---------YRKGAAI
| .... . .. ||. .. . |.|||... ...||.||||||. .| .. ..||| .| ..
----------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQ----
MPSGSGEGVQGEVASSPSSSAGACTYGR----------ANSFTGTTQYM----SPEMLRGQPHDSR----TDWWSYGCLLFE
. ...|.|| .|| .||.|.|| .| . |.|| |..|.|
---------------------------QQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYE
|
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| Kinase | LmjF03.0780.AA | AGC | 248-337 | 26 | 7.9e-37 | 91.5 | In-house | 1-134 (395) | Show / Hide |
Range on Protein: 248-337 Range on HMM: 1-134/395 Sequence Identity: 26% (35 aa) YELIAFLGSGTFAEVTLARNK------VTGEYFAVKKISKQR-VKEEG--CVERTFTE------------RQLLAKLH----------HTFLVR-LYQAF .|.. .| |.| .| |.| | ||.|.|.|...|.. ... ||.| || |. |.|.. | |.|. |. .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QSQTH--LYLVLDFAQ---------GG-DLYSLN |...| ||.|..... || .|.. . QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHL |
|||||||||
| Kinase | LmjF03.0780.AA | RSK | 1042-1158 | 34 | 8.6e-35 | 121.9 | In-house | 107-204 (278) | Show / Hide |
Range on Protein: 1042-1158 Range on HMM: 107-204/278 Sequence Identity: 34% (43 aa) AFYAIEVALVLQYLHREGFLYRDLKPENILMCR---DGHVMLTDFGVAKYRKGAAIMPSGSGEGVQGEVASSPSSSAGACT-YGRANSFTGTTQYMSPEM .||. |..| ...|| |. .||||||||| .||..||||| .|.. | .....| .| .|| ||| CFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF---------------------------RCDHNQWTMTFCYTIEYMAPEM LR---GQP-HDSRTDWWSYGCLLFE |. .| || |||| |.|..| LKRANQQGGHDKACDWWSLGVLMYE |
|||||||||
| Kinase | LmjF03.0780.AA | RSK-Unclassified | 1043-1185 | 35 | 3.5e-34 | 104.38 | In-house | 105-241 (283) | Show / Hide |
Range on Protein: 1043-1185 Range on HMM: 105-241/283 Sequence Identity: 35% (52 aa) FYAIEVALVLQYLHREGFLYRDLKPENILMCRDGHVMLTDFGVAKYR---KGAAIMPSGSGEGVQGEVASSPSSSAGACTYGRANSFTGTTQYMSPEMLR ||| || . | |||. .| ||||||.||.. .||||||||. . | . | | . . . |.||| || |. |||.| FYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGF---------RTNSFCGTEEYLAPEMIR GQPHDSRTDWWSYGCLLFEWANGRKAFNTQNQFALFRSIVEEDVKI . | ||| | ...| | . |. .| | ..||. RCGHTKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKF |
|||||||||
| Kinase | LmjF03.0780.AA | Pkinase | 1035-1184 | 26 | 8.2e-33 | 117.11 | Pfam | 102-236 (293) | Show / Hide |
Range on Protein: 1035-1184 Range on HMM: 102-236/293 Sequence Identity: 26% (44 aa) RL--PLRLIAFYAIEVALVLQYLHREGFLYRDLKPENILMCRDGHV----MLTDFGVAK-YRKGAAIMPSGSGEGVQGEVASSPSSSAGACTYGRANSFT .. . . . ||. ... |.|.|..|...|||||||||. ..||. ..|||.|| .. .. ...|. CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD---------------------------Y-NNS-MTTFC GTTQYMSPEMLR-GQPHDSRTDWWSYGCLLFEWANGRKAFNTQ------NQFALFRSIVEEDVK || ||.|| .| ||..... |.||.||.|.| ..|| | . .| .... | . ... GTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLH |
|||||||||
| Kinase | LmjF03.0780.AA | AktR | 248-335 | 28 | 4e-30 | 106.42 | In-house | 1-90 (268) | Show / Hide |
Range on Protein: 248-335 Range on HMM: 1-90/268 Sequence Identity: 28% (26 aa) YELIAFLGSGTFAEVTLARNK-VTGEYFAVKKISKQRVKEEGCVERTFTERQLLA-KLHHTFLVRLYQAFQSQTHLYLVLDFAQGGDLYS ..... ||.|.|..| |.. | .....| | |.|. .|. ..| |||. .. . | |.|.|...||....|...... .||.|.. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQ |
|||||||||
| Kinase | LmjF03.0780.AA | Akt | 248-336 | 35 | 5e-30 | 93.12 | In-house | 1-90 (264) | Show / Hide |
Range on Protein: 248-336 Range on HMM: 1-90/264 Sequence Identity: 35% (32 aa) YELIAFLGSGTFAEVTLARNKVTGEYF-AVKKISKQRVKEEGCVERTFTERQLLAKLHHTFLVRLYQAFQSQTHLYLVLDFAQGGDLYSL ... ||.|.|. | |.. | |.... | | ..|.. . . || |.||| .| . | |.| |. .||.|..||.|.|...||.|... FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYH |
|||||||||
| Kinase | LmjF03.0780.AA | AktR | 1043-1158 | 36 | 3.7e-29 | 103.18 | In-house | 105-197 (268) | Show / Hide |
Range on Protein: 1043-1158 Range on HMM: 105-197/268 Sequence Identity: 36% (43 aa) FYAIEVALVLQYLHRE-GFLYRDLKPENILMCRDGHVMLTDFGVAKYRKGAAIMPSGSGEGVQGEVASSPSSSAGACTY-GRANSFTGTTQYMSPEMLRG ||. .. | |.||| . ||||||||||. |||| .|||| .| . | .|.|| || .||.|||.. FYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK--------------------------LQFMMHYDEKAYSFCGTPEYMAPEMITK -QPHDSRTDWWSYGCLLFE ..|. |||. |....| KKGHNKSVDWWAFGIFIYE |
|||||||||
| Kinase | LmjF03.0780.AA | PKA | 248-335 | 35 | 1.8e-26 | 94.3 | In-house | 1-89 (263) | Show / Hide |
Range on Protein: 248-335 Range on HMM: 1-89/263 Sequence Identity: 35% (32 aa) YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKLHHTFLVR-LYQAFQSQTHLYLVLDFAQGGDLYS .|.|. ||.|.|. | |.|.| .|.|.| | ..||... . ||.. .|.. | ..| |.|. .|. || ..||.|.....||.. | FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFS |
|||||||||
| Kinase | LmjF03.0780.AA | Pkinase | 248-336 | 32 | 2.1e-25 | 90.88 | Pfam | 1-94 (293) | Show / Hide |
Range on Protein: 248-336 Range on HMM: 1-94/293 Sequence Identity: 32% (31 aa) YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTF-TERQLLAKLHHTFLVRLYQAFQSQTHLYLVLDFAQGG----DLYSL |... .|||.|..| ....| ||. .|||.|.|.. |.. ..... .| |....|.| . |||| .|.. .|.|.|.....|| ||... YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY |
|||||||||
| Kinase | LmjF03.0780.AA | RSK | 248-333 | 32 | 5e-23 | 79.14 | In-house | 1-88 (271) | Show / Hide |
Range on Protein: 248-333 Range on HMM: 1-88/271 Sequence Identity: 32% (29 aa) YELIAFLGSGTFAEVTLARNK---VTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKLHHTFLVRLYQAFQSQTHLYLVLDFAQGGDL |||. .| |.| .| . . . |. ..|.| | | .. .. .|| .|. || | |.|. .||.....|...||..|||| YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDL |
|||||||||
| Kinase | LmjF03.0780.AA | RSK-Unclassified | 248-334 | 32 | 4.2e-21 | 62.56 | In-house | 1-87 (283) | Show / Hide |
Range on Protein: 248-334 Range on HMM: 1-87/283 Sequence Identity: 32% (28 aa) YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKLHHTFLVRLYQAFQSQTHLYLVLDFAQGGDLY .. . .| | | .| | | | | .| | .|... . . ||. .| | | |.|| .||.| |||.... |||.. FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFF |
|||||||||
| Kinase | LmjF03.0780.AA | PKC | 248-333 | 37 | 1e-20 | 63.75 | In-house | 1-87 (262) | Show / Hide |
Range on Protein: 248-333 Range on HMM: 1-87/262 Sequence Identity: 37% (33 aa) YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKLH-HTFLVRLYQAFQSQTHLYLVLDFAQGGDL ... || | |. | ||. | | ||.|.| . | . . || | ||. || | ||. |. ||.. .|. |. . .|||| FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDL |
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| Kinase | LmjF03.0780.AA | PKC | 1033-1087 | 41 | 5.2e-20 | 61.4 | In-house | 94-148 (262) | Show / Hide |
Range on Protein: 1033-1087 Range on HMM: 94-148/262 Sequence Identity: 41% (23 aa) AHRLPLRLIAFYAIEVALVLQYLHREGFLYRDLKPENILMCRDGHVMLTDFGVAK ..|.... .||| |... ||.||. | ||||| .|.|. ..||. ..||| .| QRRFKEEHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCK |
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| Kinase | LmjF03.0780.AA | Akt | 1041-1087 | 54 | 2.4e-18 | 55.18 | In-house | 102-149 (264) | Show / Hide |
Range on Protein: 1041-1087 Range on HMM: 102-149/264 Sequence Identity: 54% (26 aa) IAFYAIEVALVLQYLHREGFLYRD-LKPENILMCRDGHVMLTDFGVAK . ||. |. | ...|| . ||| |||||||| .|||. ||||| .| ARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCK |
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| Kinase | LmjF03.0780.AA | PKA | 358-1088 | 3 | 1.2e-17 | 64.98 | In-house | 105-150 (263) | Show / Hide |
Range on Protein: 358-1088
Range on HMM: 105-150/263
Sequence Identity: 3% (24 aa)
YQSTSRTFTPAPPPAAATSNAQQHQPRASPVSARADGAQRTAGPALPRLPSSATVTQPTEVVPDVQRQQPRGSSGTATSDRDAILASSAMVGSVGPSTVS
|.
YAA-------------------------------------------------------------------------------------------------
SASRPGNTVANTATGAALPLPSARDGRASGVADGAHEAAAAVAVEEEMKEEDAKTTEFDGATDNHHSMAEAPQSAVLQRQRQSIRHAQPGAADCPSQHPR
----------------------------------------------------------------------------------------------------
LETDLFYYTTDAIDEFSTSRNVGSGGSRSSPTTPTISRTPEATESATTNAAAAAGDSAPAATRDGEVASSTASVASSGRERYRLLRRRTLPAVERDSGAR
----------------------------------------------------------------------------------------------------
GGLSVSSSSSSSTADDNSKGRRRRDTADKDGRGSSADSARRLSWRPRGVACTGPATQAEAASQHPPSPAASTPSRQTAASSASGVSTATSNTALPLATRP
----------------------------------------------------------------------------------------------------
SDLTTTDLATPKTQVPLPRSPVHFQCDERSSSSGHSNNGGGGVDEALRDDESSSAVSVKSTPSLTATKWRPMPRRASASELTDIFAVAASSAAVTVSATS
----------------------------------------------------------------------------------------------------
AAGGTSAADVKRYKTTKSAWPPATGAEQPQLASDNSHTATSATSAAATSLPRRQKGKAKVVSDKDEGSGASPPLHAGSRHSHRRAPAKKATESHDASEAA
----------------------------------------------------------------------------------------------------
ADQRSLSTDITTDAAKPLSATVTTMSFVGATAVQDAAATTAALRVDLAAPFHQVAMEGSASVLRTLPSTVFAPDGAHRLPLRLIAFYAIEVALVLQYLHR
.. | |.|||
----------------------------------------------------------------------------------------SQIVLALEYLHS
EGFLYRDLKPENILMCRDGHVMLTDFGVAKY
. ||||||||||. ..||. .|||| ||.
QNIIYRDLKPENILIDKNGHIKITDFGFAKK
|
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| Kinase | LmjF03.0780.AA | RSK | 248-334 | 28 | 9.4e-17 | 58.06 | In-house | 1-89 (278) | Show / Hide |
Range on Protein: 248-334 Range on HMM: 1-89/278 Sequence Identity: 28% (25 aa) YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGC-VERTFTERQLLAKLH-HTFLVRLYQAFQSQTHLYLVLDFAQGGDLY .. .| | . . ... || ..|.| ..| .. ...|.|||. |. | |.|.|. ||| ...|||.... ||.|. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELF |
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| Kinase | LmjF03.0780.AA | RSK | 1041-1087 | 49 | 3.1e-16 | 54.6 | In-house | 103-153 (271) | Show / Hide |
Range on Protein: 1041-1087 Range on HMM: 103-153/271 Sequence Identity: 49% (25 aa) IAFYAIEVALVLQYLHREGFLYRDLKPENILMCRD----GHVMLTDFGVAK ..||. |.|| ..||| | .||||||||| . ||. ..||| || VKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAK |
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| Kinase | LmjF03.0780.AA | S_TKc | 248-1510 | 5 | 5.8e-15 | 42.56 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 248-1510
Range on HMM: 1-231/231
Sequence Identity: 5% (67 aa)
YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKLHHTFLVRLYQAFQSQTHLYLVLDFAQGGDLYSLNVQQLWLRSMK
||.. .|.|.|..| ..|.| ||...|.|.|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------
RNLVKMQYPYYQSTSRTFTPAPPPAAATSNAQQHQPRASPVSARADGAQRTAGPALPRLPSSATVTQPTEVVPDVQRQQPRGSSGTATSDRDAILASSAM
----------------------------------------------------------------------------------------------------
VGSVGPSTVSSASRPGNTVANTATGAALPLPSARDGRASGVADGAHEAAAAVAVEEEMKEEDAKTTEFDGATDNHHSMAEAPQSAVLQRQRQSIRHAQPG
----------------------------------------------------------------------------------------------------
AADCPSQHPRLETDLFYYTTDAIDEFSTSRNVGSGGSRSSPTTPTISRTPEATESATTNAAAAAGDSAPAATRDGEVASSTASVASSGRERYRLLRRRTL
----------------------------------------------------------------------------------------------------
PAVERDSGARGGLSVSSSSSSSTADDNSKGRRRRDTADKDGRGSSADSARRLSWRPRGVACTGPATQAEAASQHPPSPAASTPSRQTAASSASGVSTATS
----------------------------------------------------------------------------------------------------
NTALPLATRPSDLTTTDLATPKTQVPLPRSPVHFQCDERSSSSGHSNNGGGGVDEALRDDESSSAVSVKSTPSLTATKWRPMPRRASASELTDIFAVAAS
----------------------------------------------------------------------------------------------------
SAAVTVSATSAAGGTSAADVKRYKTTKSAWPPATGAEQPQLASDNSHTATSATSAAATSLPRRQKGKAKVVSDKDEGSGASPPLHAGSRHSHRRAPAKKA
----------------------------------------------------------------------------------------------------
TESHDASEAAADQRSLSTDITTDAAKPLSATVTTMSFVGATAVQDAAATTAALRVDLAAPFHQVAMEGSAS---VLRTLPSTVFAPDGAHRLPLRLIAFY
.... . . . | . . || |... . . ...| ..||
-------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY
AIEVALVLQYLHREGFLYRDLKPENILMCRDGHVMLTDFGVAKYRKGAAIMPSGSGEGVQGEVASSPSSSAGACTYGRANSFTGTTQYMSPEMLRGQPHD
. .... |.|.|. |...|||||||||... |....|||.|. ..| || ||.||.| ...
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------------TTFCGTPWYMAPEVL---GYG
S-RTDWWSYGCLLFEWANGRKAFNTQNQFALFRSIVEEDVKITAEDYRLTLLEVHTRVAQLHYRAEEVRLAYEQRVARRMRRSFTPLSQSTRPQATPSAL
. |||| ||.|.| . |. | .....|. |.
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------------------------------------------------------
TAEVVYNPDNRSFDVQLRSPAMSALSFAQSGSNGAGAAAEGAEEALTGNAVKSCIPHPKDSRQLPPPLLPPSNAAATHITPHRHAHRRLHSYSYASPHST
----------------------------------------------------------------------------------------------------
ATVPKASVAVLLNDSFANQLGALGVSRTTSAEEDTQGPSPQSTLNDSFAGVESNSVVSLCGAPTNLSMRLTTTEDGVIAALLSSASSTAVHLQHQQQQQE
----------------------------------------------------------------------------------------------------
RHRRHQRRRLRLSCLNLDEATRDRYIDNAVAQMAEAQALLRDLTMKLLDRRMEHRLSGEAVLE-------HPFF
..|. .|.|.. |.|.. .|. ||.|
------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
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| Kinase | LmjF03.0780.AA | PKC | 1122-1185 | 31 | 1.5e-13 | 40.11 | In-house | 156-219 (262) | Show / Hide |
Range on Protein: 1122-1185 Range on HMM: 156-219/262 Sequence Identity: 31% (20 aa) RANSFTGTTQYMSPEMLRGQPHDSRTDWWSYGCLLFEWANGRKAFNTQNQFALFRSIVEEDVKI ....| || |..|| |..|. |||..| |..| |. | .. ||.|| .... . TTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPFHGEDEDELFQSIMHDNPHY |
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| Kinase | LmjF03.0780.AA | Akt | 1122-1185 | 35 | 2.6e-13 | 38.84 | In-house | 158-222 (264) | Show / Hide |
Range on Protein: 1122-1185 Range on HMM: 158-222/264 Sequence Identity: 35% (23 aa) RANSFTGTTQYMSPEMLRGQPHDSRTDWWS-YGCLLFEWANGRKAFNTQNQFALFRSIVEEDVKI ....| || |..||.| |. |. .|||. ||...| || | .|.. .| | ...||. KTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKF |
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| Kinase | LmjF03.0780.AA | RSK | 1121-1158 | 47 | 3.7e-09 | 29.06 | In-house | 160-197 (271) | Show / Hide |
Range on Protein: 1121-1158 Range on HMM: 160-197/271 Sequence Identity: 47% (18 aa) GRANSFTGTTQYMSPEMLRGQPHDSRTDWWSYGCLLFE | . .| .| .|| ||.|. | || ||||.| |..| GMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYE |
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| Kinase | LmjF03.0780.AA | TyrKc | 248-1201 | 5 | 1e-06 | -115.69 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 248-1201
Range on HMM: 1-280/280
Sequence Identity: 5% (58 aa)
YELIAFLGSGTFAEVTLARNKVTGEYFAVKKISKQRVKEEGCVERTFTERQLLAKL--HHTFLVRLYQAFQSQ-------THLYLVLDFAQGGDLYSLNV
.|. ||.| | || ... | . |||.. . .| | ... || || .|||| . .| |..|. .. .||| .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDY--
QQLWLRSMKRNLVKMQYPYYQSTSRTFTPAPPPAAATSNAQQHQPRASPVSARADGAQRTAGPALPRLPSSATVTQPTEVVPDVQRQQPRGSSGTATSDR
||. ...
----LRKHRPK-----------------------------------------------------------------------------------------
DAILASSAMVGSVGPSTVSSASRPGNTVANTATGAALPLPSARDGRASGVADGAHEAAAAVAVEEEMKEEDAKTTEFDGATDNHHSMAEAPQSAVLQRQR
----------------------------------------------------------------------------------------------------
QSIRHAQPGAADCPSQHPRLETDLFYYTTDAIDEFSTSRNVGSGGSRSSPTTPTISRTPEATESATTNAAAAAGDSAPAATRDGEVASSTASVASSGRER
----------------------------------------------------------------------------------------------------
YRLLRRRTLPAVERDSGARGGLSVSSSSSSSTADDNSKGRRRRDTADKDGRGSSADSARRLSWRPRGVACTGPATQAEAASQHPPSPAASTPSRQTAASS
----------------------------------------------------------------------------------------------------
ASGVSTATSNTALPLATRPSDLTTTDLATPKTQVPLPRSPVHFQCDERSSSSGHSNNGGGGVDEALRDDESSSAVSVKSTPSLTATKWRPMPRRASASEL
----------------------------------------------------------------------------------------------------
TDIFAVAASSAAVTVSATSAAGGTSAADVKRYKTTKSAWPPATGAEQPQLASDNSHTATSATSAAATSLPRRQKGKAKVVSDKDEGSGASPPLHAGSRHS
----------------------------------------------------------------------------------------------------
HRRAPAKKATESHDASEAAADQRSLSTDITTDAAKPLSATVTTMSFVGATAVQDAAATTAALRVDLAAPFHQVAMEGSASVLRTLPSTVFAPDGAHRLPL
|..
-------------------------------------------------------------------------------------------------LCM
RLIAFYAIEVALVLQYLHREGFLYRDLKPENILMCRDGHVMLTDFGVAKYRKGA--------AIMPSG--SGEGVQGEVASSPSSSAGACTYGRANSFTG
. ... .| .|||. .. ||| |.| ....| .||| ... . ..... .| ..
KDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM------------------------L
TTQYMSPEMLRGQPHDSRTDWWSYGCLLFE-WANGRKAFNTQ----NQFALFRSIVEEDVKITAEDY---------------------------RLTLLE
|.|| .. . .| ||.| ...| .| . . . . |.. .. | | |
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE
VHTRV
.| .
IHECF
|
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| Kinase | LmjF03.0780.AA | PKA | 1128-1184 | 26 | 6.1e-05 | 19.15 | In-house | 160-219 (263) | Show / Hide |
Range on Protein: 1128-1184 Range on HMM: 160-219/263 Sequence Identity: 26% (16 aa) GTTQYMSPEMLRGQ-PHDSRTDWWSYGCLLFEWANGRKAFNTQ--NQFALFRSIVEEDVK || .|. ||.. . .| |||. |.| .| . | |. ....... |.. ..| GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIK |
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| Kinase | LmjF03.0780.AA | AGC | 1489-1510 | 31 | 0.000164 | 6.0 | In-house | 364-395 (395) | Show / Hide |
Range on Protein: 1489-1510 Range on HMM: 364-395/395 Sequence Identity: 31% (10 aa) KLLDRRMEHRLS----------GEAVLEHPFF ||| . |.|| | . .||.| KLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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| Kinase | LmjF03.0780.AA | RSK | 1484-1510 | 34 | 0.000229 | 12.29 | In-house | 247-278 (278) | Show / Hide |
Range on Protein: 1484-1510 Range on HMM: 247-278/278 Sequence Identity: 34% (11 aa) RDLTMKLLDRRMEHRLS-----GEAVLEHPFF .|| |.| | . ||. | ...||.| KDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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| Kinase | LmjF03.0780.AA | RSK | 1477-1510 | 33 | 0.000395 | 10.91 | In-house | 237-271 (271) | Show / Hide |
Range on Protein: 1477-1510 Range on HMM: 237-271/271 Sequence Identity: 33% (13 aa) AEAQALLRDLTMKLLDRRMEHRLSG-----EAVLEHPFF .||. ||| ..|.| . ||. | ...||.| DEAKDLLR----MMLHRDPHNRLGAGPNGVEQIKQHPWF |
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| Kinase | LmjF03.0780.AA | Ciliate-E2-Unclassified | 1478-1510 | 36 | 0.000632 | 9.53 | In-house | 320-352 (352) | Show / Hide |
Range on Protein: 1478-1510 Range on HMM: 320-352/352 Sequence Identity: 36% (12 aa) EAQALLRDLTMKLLDRRMEHRLSGEAVLEHPFF ||. ...|| |.|. ... |.. | .|.||.| EAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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| Kinase | LmjF03.0780.AA | Ciliate-E2 | 1485-1510 | 35 | 0.000747 | 9.09 | In-house | 335-365 (365) | Show / Hide |
Range on Protein: 1485-1510 Range on HMM: 335-365/365 Sequence Identity: 35% (11 aa) DLTMK----LLDRRMEHRLS-GEAVLEHPFF || | .|.. | |.. | .|.||.| DLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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| Kinase | LmjF03.0780.AA | Pkinase | 1489-1510 | 31 | 0.007617 | 11.14 | Pfam | 272-293 (293) | Show / Hide |
Range on Protein: 1489-1510 Range on HMM: 272-293/293 Sequence Identity: 31% (7 aa) KLLDRRMEHRLSGEAVLEHPFF ..|.. .. |.. | .|.||.| WCLCKDPKKRPTAEQILQHPWF |
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| Kinase | LmjF03.0780.AA | AktR | 1483-1510 | 32 | 0.031722 | 4.9 | In-house | 235-268 (268) | Show / Hide |
Range on Protein: 1483-1510 Range on HMM: 235-268/268 Sequence Identity: 32% (11 aa) LRDLTM-KLLDRRMEHRLS-----GEAVLEHPFF ..|| |||... ..|| | . .||.| CKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF |
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| Kinase | LmjF03.0780.AA | RSK-Unclassified | 1484-1510 | 43 | 0.058015 | 1.37 | In-house | 252-283 (283) | Show / Hide |
Range on Protein: 1484-1510 Range on HMM: 252-283/283 Sequence Identity: 43% (14 aa) RDLTMKLLDRRMEHRL---SG--EAVLEHPFF ||| ||| | || .| . . |||| RDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF |
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| Kinase | LmjF03.0780.AA | PKC | 1502-1510 | 55 | 0.156954 | 0.53 | In-house | 254-262 (262) | Show / Hide |
Range on Protein: 1502-1510 Range on HMM: 254-262/262 Sequence Identity: 55% (5 aa) EAVLEHPFF ... ||||| QDIREHPFF |
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