Gene LmjF35.4620 (L.major)

LmjF35.4620

Species: L.major
Alias: LmajK144, LmjF35.4620
External Links:
Annotation:

Classification

Group: Other
Family: Other-Unique

Sequence

Name Sequence Type Origin Length Description Download
LmjF35.4620.AA Protein None 288 None Fasta, JSON
LmjF35.4620.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of LmjF35.4620.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF35.4620.AA Pkinase 165-248 20 8.4e-11 39.27 Pfam 178-293 (293) Show / Hide 
Range on Protein: 165-248
Range on HMM: 178-293/293
Sequence Identity: 20% (25 aa)

AAPEILR-GDPYAGAADVWGLGVLLVQLLLGSSKPVCTADL----ENSDLLSPFISSLG-------------------------------PSAASFVLPC
.|||..| | .|  ..|.|..|..| ..|.|   | .  .     .  | .  .   .|                               ... .|.  |
MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR--PPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

VKSDPHARPLLLEVLQHPFL
 . ||. ||   ..||||..
LCKDPKKRPTAEQILQHPWF
Kinase LmjF35.4620.AA PKC 166-196 41 3.2e-09 25.85 In-house 168-198 (262) Show / Hide 
Range on Protein: 166-196
Range on HMM: 168-198/262
Sequence Identity: 41% (13 aa)

APEILRGDPYAGAADVWGLGVLLVQLLLGSS
|||||....|  . | | .|||. ....| |
APEILQYQEYGKSVDWWAFGVLMYEMMAGQS
Kinase LmjF35.4620.AA AGC 166-248 20 1.1e-08 17.04 In-house 275-395 (395) Show / Hide 
Range on Protein: 166-248
Range on HMM: 275-395/395
Sequence Identity: 20% (25 aa)

APEILRGDPYAGAADVWG--LGVLLVQLLLG-----------------SSKPVCTADLE-----NSDLLSPFI--------SSLGPSAASFVLPCVKSDP
|||||    |  |.| |.  ||.|. ..| |                 . . .    ..     | ..  ||         ... | | ...  . . ||
APEIL----YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDP

HARPL----------LLEVLQHPFL
  |.             |. .||. 
EKRLGCGGNDFGDKGAEEIKNHPWF
Kinase LmjF35.4620.AA Ciliate-E2-Unclassified 165-248 22 8.3e-08 23.19 In-house 233-352 (352) Show / Hide 
Range on Protein: 165-248
Range on HMM: 233-352/352
Sequence Identity: 22% (27 aa)

AAPEILRGDPYAGA----ADVWGLGVLLVQLLLGSSKPV----CTA---------------DLENSDL-----LSPFIS-----SLGPSAASFVL----P
.|||.|.|  | .     .|.|.|||.| ..| |   |     |.                 |..  .      ..|        . |.|. |.      
TAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY-YPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQK

CVKSDPHARPLLLEVLQHPFL
. | .|  |. . ..|.||..
MLKKNPNKRITFEQILNHPWF
Kinase LmjF35.4620.AA Trio 165-187 47 1.8e-07 14.52 In-house 167-189 (258) Show / Hide 
Range on Protein: 165-187
Range on HMM: 167-189/258
Sequence Identity: 47% (11 aa)

AAPEILRGDPYAGAADVWGLGVL
.||||. |.|  ...|.|. |||
MAPEIIQGNPVSYGTDIWSIGVL
Kinase LmjF35.4620.AA Iota 166-196 51 5.2e-07 18.89 In-house 168-198 (271) Show / Hide 
Range on Protein: 166-196
Range on HMM: 168-198/271
Sequence Identity: 51% (16 aa)

APEILRGDPYAGAADVWGLGVLLVQLLLGSS
|||||||. |  . | | ||||.  .. | |
APEILRGEDYGFSVDWWALGVLMFEMMAGRS
Kinase LmjF35.4620.AA CAMK 165-188 28 1e-06 16.63 In-house 286-324 (425) Show / Hide 
Range on Protein: 165-188
Range on HMM: 286-324/425
Sequence Identity: 28% (11 aa)

AA-PEILRG--------------DPYAGAADVWGLGVLL
.| ||.|.|              ..|  ..|.| .||.|
MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL
Kinase LmjF35.4620.AA CAMKL 165-188 44 2e-06 16.05 In-house 200-226 (297) Show / Hide 
Range on Protein: 165-188
Range on HMM: 200-226/297
Sequence Identity: 44% (12 aa)

AAPEILRG--DPYA-GAADVWGLGVLL
.||||. |  .||   ..|.| .||.|
MAPEIFQGNNKPYDGPKVDIWSCGVIL
Kinase LmjF35.4620.AA MARK 164-188 46 3e-06 16.55 In-house 171-196 (262) Show / Hide 
Range on Protein: 164-188
Range on HMM: 171-196/262
Sequence Identity: 46% (12 aa)

CAAPEILRGDPYA-GAADVWGLGVLL
..||||. . ||   ..|.| |||.|
YMAPEIFLKKPYDGPKVDIWSLGVVL
Kinase LmjF35.4620.AA CASK 166-195 50 5e-06 15.2 In-house 241-270 (330) Show / Hide 
Range on Protein: 166-195
Range on HMM: 241-270/330
Sequence Identity: 50% (15 aa)

APEILRGDPYAGAADVWGLGVLLVQLLLGS
|||. | .||    |.|| ||.|  || |.
APEVVRREPYGCPCDIWGCGVMLFILLSGC
S_TKc LmjF35.4620.AA S_TKc 16-248 13 1e-05 -92.72 SMART 16-231 (231) Show / Hide 
Range on Protein: 16-248
Range on HMM: 16-231/231
Sequence Identity: 13% (39 aa)

QQGAWTR--------RIRKSDVYPSSLEAIRARVEALRGRWRGGGAAYVVPITRAVCTPLYLRLEVDESLALELLGP---PWEYERHSAP-------MGE
 .. ...        .|.         | ||  .. |.      .  ..| .  .  .        .  . .|...          .. .       . |
YKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-----HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE

RDAALCVLSVAQLLSRLHAVGVVH----------------------GHLQAGVVWHHTGDALRIVVTECELPMTALVPYGGVGSEARRCAAPEILRGDPY
 .|.  .  ... |  .|  |..|                       .|                             .  .|.  .   |||.|   .|
-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-----------------------------TTFCGT--PWYMAPEVL---GY

AG-AADVWGLGVLLVQLLLGSS---KPVCTADLENSDLLSPFISSLGPSAASFVLPCVKSDPHARPLLLEVLQ-------HPFL
 . ..|.| .|..|  .| |      .  . ..              |.| .|.  | . ||  ||   |.||       ||..
GKCKCDWWSCGCILYEMLCGYPPFPQMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF35.4620.AA RSK 165-196 36 1.1e-05 17.15 In-house 175-210 (278) Show / Hide 
Range on Protein: 165-196
Range on HMM: 175-210/278
Sequence Identity: 36% (13 aa)

AAPEILR---GDP-YAGAADVWGLGVLLVQLLLGSS
.|||.|.   ..  .  |.|.| ||||.  .| | .
MAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCP
Kinase LmjF35.4620.AA CAMK 232-248 35 0.001492 6.52 In-house 409-425 (425) Show / Hide 
Range on Protein: 232-248
Range on HMM: 409-425/425
Sequence Identity: 35% (6 aa)

DPHARPLLLEVLQHPFL
||  |. . ..|.||..
DPEKRMTIEQCLNHPWM
Kinase LmjF35.4620.AA MARK 232-248 35 0.004768 6.0 In-house 246-262 (262) Show / Hide 
Range on Protein: 232-248
Range on HMM: 246-262/262
Sequence Identity: 35% (6 aa)

DPHARPLLLEVLQHPFL
.|. || . |...||..
NPEERPTIEEIMKHPWM
Kinase LmjF35.4620.AA RSK 215-248 25 0.010603 6.14 In-house 240-278 (278) Show / Hide 
Range on Protein: 215-248
Range on HMM: 240-278/278
Sequence Identity: 25% (10 aa)

SSLGPSAASFVLPCVKSDPHARPL-----LLEVLQHPFL
..| . | ...  . . ||| |.      . |..|||..
QYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase LmjF35.4620.AA CASK 232-248 47 0.027505 2.85 In-house 314-330 (330) Show / Hide 
Range on Protein: 232-248
Range on HMM: 314-330/330
Sequence Identity: 47% (8 aa)

DPHARPLLLEVLQHPFL
||| |    |.| || .
DPHHRISIYEALNHPWI
Kinase LmjF35.4620.AA CAMKL 232-248 29 0.043437 2.29 In-house 281-297 (297) Show / Hide 
Range on Protein: 232-248
Range on HMM: 281-297/297
Sequence Identity: 29% (5 aa)

DPHARPLLLEVLQHPFL
.|  || . ....||..
NPEKRPTIHQIMNHPWM