Gene LmjF11.0060 (L.major)

LmjF11.0060

Species: L.major
Alias: LmjF11.0060, LmajK146
External Links:
Annotation:

Classification

Group: Other
Family: PEK
Subfamily: GCN2

Sequence

Name Sequence Type Origin Length Description Download
LmjF11.0060.AA Protein None 1126 None Fasta, JSON
LmjF11.0060.kin_dom Protein Kinase Domain None 390 None Fasta, JSON

Protein domain

Protein domains of LmjF11.0060.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF11.0060.AA PEK 177-566 18 2.7e-64 219.89 In-house 1-655 (655) Show / Hide 
Range on Protein: 177-566
Range on HMM: 1-655/655
Sequence Identity: 18% (124 aa)

FIQQRLLGAGGF-APVYVCRKKIDGRLYAIKKIAMTEAQ------------------SEKVLREVQTLAALNHKNIVRYYDAWVE---------------
|.. ..|| |||   || .. |.||..||||.|.   .|                  .|||||||.||| |||.|||||. || |               
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARLNHPNIVRYHNAWIEKPEEKWQQQQDEMWQ

--------DGCDEDLREFVDTDAEDEEDEEDEEIKHGGKMLSPQ-----------SRAAARASLSSDTDRTASLYSSAEEKS------------------
        .|....   . .   |.|. .. ||   .. |   .           .   . .| .   ... . . |... |                  
LDSSTDWPNGKHKSKDYNFH-PFEKEW-DD-EEAQESNVMSE-CEDREQKGKKKCWSESNSHSSKNNYEESMEWSCSEHSDSSSFPNIENQFSINFGTEN

-----------SSVDTSEEDDESGESCSDSGDARSD----------------------------------------------------------------
           |....|..|.....|.|.| | ...                                                                
ENESHISYWSSSVYMSSSWDNPFDSSFSNSCDSTNFNKDEDHSFFSCSSYSSCSTDCDDSKDSSPFNWDGGCDNWEQYEYSDQDDEHEQNDCQSKQCDSK

-------VKMHE-------------------------------PKGRRPSMN------FQTLYIQMELCSARSLRHLIDES---------------DSSD
       . |..                                |   ..|.      ...||||||.|.  .||..||..                 . 
NQSHKKCMEMTWIQDQEDNKNNCSHHIGSSSQSQEEMENNTNNNKNKFKQMHNTKQYQCHYLYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYN

SGGIFS--------------------SANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVADFGLAR-------------
.  | .                    . . .... .|.||.|.  .. |   ..|||||| |... ....|     .....|||||              
NY-IMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPSNIFLDCDGQHHQ--MQVKIGDFGLATNHEMLSQSQKNYN

----------VMSGVKRIRSVLD--VDEVN------------TPTNLVSANYPTGNCGSVLYCAPEQEKGL-----EYDFKVDEFSIGMIAFEMWLAIAG
          .... . ..   .   ....            |. .  ...  ||..| .||..|||..|       |. ||| .| | | ||||  .  
QQDQSYWKYVANDNCQWWNTNQQNSPTGQDTHMWSNNYHIQPTSMFYCEHCHHTGGVGTCLYMSPEQLSGQHYQKSHYNHKVDMYSLGIIFFEMWYPFFT

KGFRERFTIMGEVWRT------GKLP-QWFARWNPTMADIIEKLLEPDPRRRTTCEAVLSTAEL
 .. ||....  . |.      |..|  ||.   |  ||.| ..| .||. | . .  |..  .
TMM-ERVKTLTDL-RDESIQFPGDFPPKWFDNKYPKQADFIQWMLSHDPQQRPSAQQILQHEFF
Kinase LmjF11.0060.AA CAMK 182-503 15 1.7e-34 108.02 In-house 1-327 (425) Show / Hide 
Range on Protein: 182-503
Range on HMM: 1-327/425
Sequence Identity: 15% (65 aa)

LLGAGGFAPVYVCRKKIDG------------RLYAIKKIAMTEAQS-----------------------------EKVLREVQTLAA-------LNHKNI
 || |.|. |. |. | ..            . .||| |  . ...                             ..|.||.. .         |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYYDAWVEDGCDEDLREFVDTDAEDEEDEEDEEIKHGGKMLSPQSRAAARASLSSDTDRTASLYSSAEEKSSSVDTSEEDDESGESCSDSGDARSDVKM
.. |...  . .      .                                                                                 
IKLYEVYEDPHYFK-N--T---------------------------------------------------------------------------------

HEPKGRRPSM-NFQT--------LYIQM---ELCSAR----SLRHLIDES-------DSSDSGGIFSSANG----------ETVAVSILRQLLSVTAHTH
      ..   . ..        .|. |   |.||       |   | |        |                       |  |  . ||..|  .. |
------ND-YET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFD------------QFDIVERGRFTEREARRYFRQICSAVHYCH

RERIVHRDLKPENVLF-EMESNHN---------SEAGIIRVADFGLARVMSGVKRIRSVLDVDEVNTPTNL-----VSANYPTGNCGSVLYCA-PEQEKG
   ||||||||||.|. . ... .         .. . | ..|||.|... . .  .   |... .   .       .    .  ||.  |.| ||  .|
SHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNG

--------------LEYDFKVDEFSIGMIAFEM
                |..|.|  |.| | . |
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIM
Kinase LmjF11.0060.AA STE 177-503 14 2.9e-31 107.7 In-house 1-261 (359) Show / Hide 
Range on Protein: 177-503
Range on HMM: 1-261/359
Sequence Identity: 14% (58 aa)

FIQQRLLGAGGFAPVYVCRKKI---------------DGRLYAIKKIAMTEAQ------------------SEKVLREVQTLAALN--HKNIVRYYDAWV
.  .. .| |.|  || ....                 |...|||.. . . .                   ...|.|....  .|  |.|||.||.. .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EDGCDEDLREFVDTDAEDEEDEEDEEIKHGGKMLSPQSRAAARASLSSDTDRTASLYSSAEEKSSSVDTSEEDDESGESCSDSGDARSDVKMHEPKGRRP
 .| .                                                                                               
KEGHN-----------------------------------------------------------------------------------------------

SMNFQTLYIQMELCSARSLRHLID---ESDSSDS-----GGIFSSANGETVAVSILRQLLSV-TAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVA
. | ..|.| ||.... ||. .|.   .   ...     .. |.    |..   |.||.|    .. |. .|.|||.|| |.|.            .  .
HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFP----ESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------------VKLC

DFGLARVMSG----------VKRIRSVLDVDEVNTPTNLVSANYPTGNC------------GSVLYCAPEQEKG------LEYDFKVDEFSIGMIAFEM
|||..  ..           .                          .|            |.  . |||  ..       .||.|.|  |.|  . ||
DFGVCGQLTDSMANIQSNNII--------------------------DCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase LmjF11.0060.AA GCN2 175-437 19 4.2e-31 105.91 In-house 1-355 (511) Show / Hide 
Range on Protein: 175-437
Range on HMM: 1-355/511
Sequence Identity: 19% (72 aa)

NEFIQQRLLGAGGFAPVYV-CRKKIDGRLYAIKKIAM--TEAQSEK---VLREVQTLAALNHKNIVRYYDAWVEDGCD---EDLREFVDTDAEDEEDEED
.|.|.  .|| |||  |.   | . |||.|||||..   .. . ..    .||| .|. |.| ..|||| ||.|.  .   .|  .. ||.. .. | | 
FEEIC--CLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLCRLHHQHVVRYYQAWIEKCDEPMVTDTNNDDDTNNNYHSDDES

EEIKHGGKMLSPQSRAAARASLSSDTDRTASLYSSAEEKSSSVDTSEEDD--------------------------------------------------
|  .   .|..  . ..  .....      |. .. .. ...    .|.|                                                  
ECFSGQYEMPKSVNQSEEMCNKEESMEWSMSNERNNSNWHDNGNFFSEWDNPFDQPFGPKCAFRMGQKRTFDLTDDHYSYCHSDCEFDDDVFDIDWDIES

-------ESGESCSDSGDARSD--------------------------------------VKMHEPKGRRPSM------NFQTLYIQMELCSARSLRHLI
       .. .. .....  ..                                      .  | .| .  .|       ...|||||| |. ..||..|
NNVRDMESDDNEWEQEQQNNQSFQPKQEDHQNQYYDQEDLNNAESEDQNKKKSQQQDKMCQNQHKNKVHYKCMNCKKPKEVHYLYIQMEYCEGKTLRQYI

DES----DSSDSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVADFGLA
|..    |.               . ...||.|.  .. |   ..|||||| |...  .       | ....|||||
DNHGWCMDHD-------------ELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFLDCC-------GNVKIGDFGLA
Kinase LmjF11.0060.AA HRI 177-243 45 4.2e-25 85.06 In-house 1-70 (613) Show / Hide 
Range on Protein: 177-243
Range on HMM: 1-70/613
Sequence Identity: 45% (32 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTEAQS---EKVLREVQTLAALNHKNIVRYYDAWVED
|.|   .| ||.  ||  | | |.  ||||||  .....    |..||| .|| |.| |||||  ||.|.
FEQKEIIGKGGYGRVYKVRHKLDKQHYAIKKIKIKKRTKCSCMKMQREVKVLACLQHHNIVRYHQAWIEH
Kinase LmjF11.0060.AA S_TKc 177-566 17 4.6e-24 87.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 177-566
Range on HMM: 1-231/231
Sequence Identity: 17% (73 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTEAQSEKVLREVQTLAALNHKNIVRYYDAWVEDGCDEDLREFVDTDAEDEEDEEDEEIKHGGKMLS
.   |..| |.|. || ||.| .||..|||.|                                                                    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

PQSRAAARASLSSDTDRTASLYSSAEEKSSSVDTSEEDDESGESCSDSGDARSDVKMHE------PKGRRPSMNFQTLYIQMELCSA--RSLRHLIDESD
                                                 ..|. .....       |      . . ||. ||.|.    .|...|..  
------------------------------------------------EHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

SSDSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVADFGLARVMSGVKRIRSVLDVDEVNTPTNLVSANYPT
.   .  |.    | .| ....|...  .. |. .|.||||||||.|.            | ..||||||..                           |
RHGLRFPFP----E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---------HIKICDFGLARQL---------------------------T

GNCGSVLYCAPEQEKGLEYDF-KVDEFSIGMIAFEMWL---AIAGKGFRERFTIMGEVWRTGKLPQWFARWNPTMADIIEKLLEPDPRRRTTCEAVLS--
  ||.  |.|||      |.. |.|  |.| | .||             . | ..|                | . |.|.|.|. ||..| |.  .|   
TFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDE

-----TAEL
        .
WDIKCHPWF
Kinase LmjF11.0060.AA Pkinase 343-503 27 7.3e-24 85.45 Pfam 70-205 (293) Show / Hide 
Range on Protein: 343-503
Range on HMM: 70-205/293
Sequence Identity: 27% (45 aa)

MNFQTLYIQMELCSAR----SLRHLIDESDSSDSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVADFGLAR
.. . .|. ||.|       .| ..|      ...| |.    | .. ....|.|.  .. |...|.||||||||.|.  . .|...  .....|||||.
EDKDHIYMVMEYCEGGLYVMDLFDYIST----WRHGCFY--FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDA--CVKICDFGLAK

VMSGVKRIRSVLDVDEVNTPTNLVSANYPTGNCGSVLYCAPEQEK-GLEYDFKVDEFSIGMIAFEM
...                   . .   .|. ||.  |.|||  . | .|. ||| .|.| | .||
QFD-------------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEM
Kinase LmjF11.0060.AA PEK 177-242 44 2.1e-22 70.54 In-house 1-76 (758) Show / Hide 
Range on Protein: 177-242
Range on HMM: 1-76/758
Sequence Identity: 44% (34 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTE--------AQS--EKVLREVQTLAALNHKNIVRYYDAWVE
|     || |||  |.    | |. .||||.|.           . |  |||.||| ||| |.| |||||. || |
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTLAMLDHHNIVRYFNAWLE
Kinase LmjF11.0060.AA Ciliate-E2 343-503 20 2.4e-21 69.99 In-house 104-289 (365) Show / Hide 
Range on Protein: 343-503
Range on HMM: 104-289/365
Sequence Identity: 20% (45 aa)

MNFQTLYIQMELCSARSLRHLIDESDSSD------SGGIFSSANGETVAVSILRQLLSVT---------------AHTHRER-IVHRDLKPENVLFEMES
.. ...|. ||.|.  .|...| ... .         . |.    |  .  | .|.|..                 . | .  |.|||.||||.||    
KDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFT----EKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

NHNSEAGIIRVADFGLAR-------------------------VMSGVKRIRSVLDVDEVNTPTNLVSANYPTGNCGSVLYCAPEQEKGLE---------
        | ..||||..                         ...|  ..               .. |     ||.  | |||  .| .         
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQ--------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKG

YDFKVDEFSIGMIAFEM
||.|.| .|.|.| .||
YDYKCDIWSLGVILYEM
Kinase LmjF11.0060.AA PEK-Unclassified 177-242 40 2.5e-21 70.75 In-house 1-74 (835) Show / Hide 
Range on Protein: 177-242
Range on HMM: 1-74/835
Sequence Identity: 40% (30 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMT--------EAQSEKVLREVQTLAALNHKNIVRYYDAWVE
|.| . .| |||| || |  |.|   ||.|.| .             || ..||  .| .|| ||.|||  |.|
FNQVQKIGQGGFAIVYQCCHKFDQMEYAVKQIHVNIKDIKEDLQKHYEKEIMEVRYMAQVNHPNIIRYYHSWIE
Kinase LmjF11.0060.AA WEE 177-244 39 2.6e-21 68.31 In-house 1-78 (297) Show / Hide 
Range on Protein: 177-244
Range on HMM: 1-78/297
Sequence Identity: 39% (31 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIA--MTEAQS-EKVLREVQTLAALN-------HKNIVRYYDAWVEDG
| .   .| | |. || ||..|||..|||||.     . .. .  ||||. .. |        |..||||| || ||.
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDD
Kinase LmjF11.0060.AA STE-Unique 178-257 31 5.3e-17 56.45 In-house 1-96 (616) Show / Hide 
Range on Protein: 178-257
Range on HMM: 1-96/616
Sequence Identity: 31% (30 aa)

IQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTEAQ-------SEKVLREVQTLAALNHKNIVRYYDAWVEDGCD---------EDLREFVDTDA
. |  .| |.|  |. |. | |.. .|||.|              .. ..|......|.| |||.|| .| . |||         |||   ..|||
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQFKDFNQEPLVNMIISEIEIMKCLHHQNIVKYYGHWLWGGCDSFQSLEEGNEDLSGDLETDA
Kinase LmjF11.0060.AA Pkinase 177-244 35 1.9e-15 55.67 Pfam 1-73 (293) Show / Hide 
Range on Protein: 177-244
Range on HMM: 1-73/293
Sequence Identity: 35% (26 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTEAQSEK---VLR--EVQTLAALNHKNIVRYYDAWVEDG
.   | .|.|.|. || |..| .|...|.|.|   .. |.|    .|  |.| .. |||.||||.||.. ...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKD
Kinase LmjF11.0060.AA HRI 348-546 30 6.7e-15 48.27 In-house 394-593 (613) Show / Hide 
Range on Protein: 348-546
Range on HMM: 394-593/613
Sequence Identity: 30% (64 aa)

LYIQMELCSARSLRHLIDESDSS------DSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESN-HNSEAGIIRVADFGLAR--
|.|||.||.  ||.  | |          ..   .  || | |.  |  |..      |   |||||.|| |.      . |      ... |||||.  
LHIQMQLCEL-SLWDWISERNKRSREYVDETECPYVMAN-EKVIQKIFQQIVEGMFYIHNMFIVHRDVKPRNIFLHDPDQGHP----QVKIGDFGLACED

VMSGV---KRIRSVLDVDEVNTPTNLVSANYPTGNCGSVLYCAPEQEKGLEYDFKVDEFSIGMIAFEMWLAIAGKGFRERFTIMGEVWRTGKLPQWFARW
..       | |   | |. |     |.  . |   |  .| .|||  | .|| | | .|.|.| ||..         || ...  | |||..|    . 
ILQEPKTPMRFRRDQDFDWTNR-NPCVTQTH-TSRVGTCTYASPEQLDGSQYDNKSDMYSMGVILFELFQPFGTE--MERAEVLTGV-RTGQIPESLRKR

NPTMADIIEKL
 |  |  |  |
CPVQAKYIQHL
Kinase LmjF11.0060.AA STE-Unique 339-566 19 4.2e-14 45.96 In-house 360-616 (616) Show / Hide 
Range on Protein: 339-566
Range on HMM: 360-616/616
Sequence Identity: 19% (54 aa)

RRPSMNFQTLYIQMELCSARSLRHLIDESDSSDSGGI---------FSSANGETVAVSILRQLLSVTAHTHRER--IVHRDLKPENVLFEMESNHNSEAG
..|     ...|.||.|.  .|. .|...      |.         |     || .  ...|.|    . |  .  |.|||||| |...  .       |
KKPPKEQNWVWIFMEYCEHGTLQQIIKRC------GCPGNPNNLQLFP----ETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQD-------G

-----IIRVADFGLARVMSGV--KRIRSVLDVDEVNTPTNL----------------VSANYPTGNCGSVLYCAPEQEKGL-----EYDFKVDEFSIGMI
      ....|||.|  .. .      .       .  .|                  .   ....||   |..||   .      .|| ||| .|.|..
KGRVCKVKICDFGHATCCQPDHFEKDNNSKNSNTWININNNSSTNSTAQQTPMWDLNINNYTMKYCCGTPCYMCPEVINCRNQINNPYDTKVDIWSLGCM

AFEMWLAIAGKGFRERFTIMG--EVWRTGKLPQW-------FARWNPTMADIIEKLLEPDPRRRTTCEAVLSTAEL
 |.|        . .|. .    |    .. ..        .    | ....|||.||..|  | . .  |    |
CFHMCCGC--PPWHQRYHMQAYIEMCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL
Kinase LmjF11.0060.AA PEK 467-566 24 4.9e-11 31.86 In-house 645-758 (758) Show / Hide 
Range on Protein: 467-566
Range on HMM: 645-758/758
Sequence Identity: 24% (29 aa)

PTGNCGSVLYCAPEQEKGL----------------EYDFKVDEFSIGMIAFEMWLA-IAGKGFRERFTIMGEVWRTGKLPQWFARWNPTMADIIEKLLEP
.|.. |  || .||| ..                  |. ||| .| | |.||.    .      || ..|  . | |..| ||.   |  .. |  .. .
HTVQVGTHLYMSPEQCHHQSVFGTGTYTNPEQKKTWYNHKVDIYSLGLIFFELIHPGFSTQ--MERIRTMCDL-RNGQWPKWFTQKYPQEYEFIQQMMSM

DPRRRTTCEAVLSTAEL
.|  | |   ... .  
NPDERPTADQISMHDFF
Kinase LmjF11.0060.AA Ciliate-E2 177-243 19 3e-10 31.36 In-house 1-105 (365) Show / Hide 
Range on Protein: 177-243
Range on HMM: 1-105/365
Sequence Identity: 19% (20 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIK---------------------KIAMTEAQSEKVLREVQTLAALN----------------HKNIVRYYDA
.. ....| |.|. || |... .....|||                     .  | . | | ...| . .  .|                |.||...|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WVE-D
. | |
FQEKD
Kinase LmjF11.0060.AA PEK 347-437 27 9.2e-10 27.52 In-house 413-513 (758) Show / Hide 
Range on Protein: 347-437
Range on HMM: 413-513/758
Sequence Identity: 27% (30 aa)

TLYIQMELCSARSLRHLIDESDSSDSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNH---------------NSEAG--II
..||||.||   .|. ..  . . .|       . ...  ..  |...     |   . |||||| |. | |.| |               ||. |  ||
YMYIQMQLCRKETLKDWMRNRCTMES-------RPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNIFFSMDSQHHQQSSFSNISSSFEENSDGGHQII

RVADFGLA
 . ||||.
KIGDFGLV
Kinase LmjF11.0060.AA GCN2 468-566 30 2.2e-08 25.01 In-house 411-511 (511) Show / Hide 
Range on Protein: 468-566
Range on HMM: 411-511/511
Sequence Identity: 30% (32 aa)

TGNCGSVLYCAPEQEKGLEYDFKVDEFSI-GMIAFEMWLA-IAGKGFRERFTIMGEVWRTGKLPQWFA---RWNPT-MADIIEKLLEPDPRRRTTCEAVL
||. |  .|..|||.    |. ||| .|  | | ||||       .. ||. |  .     ..|| |    .  ..  .|.|...| .||..| . .  |
TGKVGTPFYMCPEQQ-KSHYNQKVDMYSLGGIIFFEMWYPPF--CTQMERVQILKQLR-SCEFPQDFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLL

STAEL
 .  |
QHEFL
Kinase LmjF11.0060.AA TyrKc 177-564 12 3.7e-08 -90.82 SMART 1-280 (280) Show / Hide 
Range on Protein: 177-564
Range on HMM: 1-280/280
Sequence Identity: 12% (53 aa)

FIQQRLLGAGGFAPVYVCRKKIDGRLYAIKKIAMTEAQSEKVLREVQTLAAL--NHKNIVRYYDAWVEDG----------------CDEDLREFVDTDAE
    . || | |  || .. |   .  |.|..       |  .|| . .  |  .|.|||| | . ...|                .  ||...     .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

DEEDEEDEEIKHGGKMLSPQSRAAARASLSSDTDRTASLYSSAEEKSSSVDTSEEDDESGESCSDSGDARSDVKMHEPKGRRPSMNFQTLYIQMELCSAR
.                                                                                    . ..| ... .  |.
K-----------------------------------------------------------------------------------LCMKDL-LSFCWQIAC

SLRHLIDESDSSDSGGIFSSANGETVAVSILRQLLSVTAHTHRERIVHRDLKPENVLFEMESNHNSEAGIIRVADFGLARVMSGV-KRIRSVLDVDEVNT
  ..| .                                     ...||||   |.|   .        .....||||.|      ..         ...
GMEYLHSK------------------------------------NCIHRDLAARNCLVGENH-------TVKISDFGLSRDIYDDDQQG--------ESK

PTNLV----SAN--YPTGNCGSVLYCAPEQEKGLEYDFKVD----------------EFSIG-----MIAFEMWLAIAGKGFRERFTI---MGEVWRTGK
 .  .    ...   |      .  .|||  .  .. .| |                .   |     | ..|.   .   . ...      |        
DYYRKKEHKGGKTMLP------IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS-------

LPQWFARWNPTMADIIEKLLEPDPRRRTTCEAVLSTA
    | .  . | .|...  . ||  | | ... .  
----FVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LmjF11.0060.AA PEK-Unclassified 468-564 26 9.9e-07 18.32 In-house 731-835 (835) Show / Hide 
Range on Protein: 468-564
Range on HMM: 731-835/835
Sequence Identity: 26% (29 aa)

TGNCGSVLYCAPEQE-----------KGLEYDFKVDEFSIGMIAFEMWLAIAGKGFRERFTIMGEVWRTGKLPQWFARWNPTMADIIEKLLEPDPRRRTT
|  ||  .|  .|||            .  |. . | .|.| | |.|   .  .   || . .  . . | ||. |    | .|.||   |  || .|  
TSTCGTYTYSSNEQESQKKVRIKAHFQADFYNHRTDIYSVGIIFFQMFHQM--NTTMERVKTIQNCKK-GELPKHFCAKFPRLAEIIKDSLSNDPQKRPL

CEAVLSTA
   .  | 
LSKIEQTL
Kinase LmjF11.0060.AA WEE 388-437 22 1.3e-05 14.85 In-house 116-179 (297) Show / Hide 
Range on Protein: 388-437
Range on HMM: 116-179/297
Sequence Identity: 22% (15 aa)

ILRQLLSVTAHTHRE-RIVHRDLKPENVLFEMESN---------------HNSEAGIIRVADFGLA
||....   .| | .  .|| |.||||... ...|               . .  ...  .|||..
ILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWW-FN-MMCKIGDFGHV
Kinase LmjF11.0060.AA Pkinase_Tyr 177-237 28 2e-05 19.0 Pfam 1-70 (270) Show / Hide 
Range on Protein: 177-237
Range on HMM: 1-70/270
Sequence Identity: 28% (20 aa)

FIQQRLLGAGGFAPVYVCRKK----IDGRLYAIKKI--AMTEAQ--SEKVLREVQTLAAL-NHKNIVRYY
 .  . ||.| |  || .. |     ..   |.|..    .. |  .|. .||....  | .|.||||.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY
Kinase LmjF11.0060.AA PEK-Unclassified 385-414 38 0.000176 10.23 In-house 615-645 (835) Show / Hide 
Range on Protein: 385-414
Range on HMM: 615-645/835
Sequence Identity: 38% (12 aa)

AVSILRQLLSVTAHTHRER-IVHRDLKPENV
.  |.|| .    | |    .||||.||.|.
CREITRQIIKALYHIHHQCKMVHRDIKPHNI
Kinase LmjF11.0060.AA WEE 547-566 40 0.000286 10.31 In-house 278-297 (297) Show / Hide 
Range on Protein: 547-566
Range on HMM: 278-297/297
Sequence Identity: 40% (8 aa)

LEPDPRRRTTCEAVLSTAEL
..|||..| ||.. |.. .|
MHPDPEQRPTCQQLLQHPVL
Kinase LmjF11.0060.AA CAMK 541-562 45 0.007498 4.22 In-house 400-421 (425) Show / Hide 
Range on Protein: 541-562
Range on HMM: 400-421/425
Sequence Identity: 45% (10 aa)

DIIEKLLEPDPRRRTTCEAVLS
| | |.|..|| .| |.| .|.
DLIRKMLQVDPEKRMTIEQCLN
Kinase LmjF11.0060.AA Pkinase 534-563 33 0.028943 9.09 Pfam 261-290 (293) Show / Hide 
Range on Protein: 534-563
Range on HMM: 261-290/293
Sequence Identity: 33% (10 aa)

RWNPTMADIIEKLLEPDPRRRTTCEAVLST
.|.... |.|...|..|| .| |.| .|  
NWSEECKDFIKWCLCKDPKKRPTAEQILQH
Kinase LmjF11.0060.AA Ciliate-E2 529-566 26 0.033416 3.34 In-house 321-365 (365) Show / Hide 
Range on Protein: 529-566
Range on HMM: 321-365/365
Sequence Identity: 26% (12 aa)

PQW--FARWNPTMADIIEK----LLEPDPRRRTT-CEAVLSTAEL
. |  .  | . . |.| |    .|. ||  | |  | .|    .
CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF11.0060.AA PEK-Unclassified 348-364 52 0.070763 0.87 In-house 502-518 (835) Show / Hide 
Range on Protein: 348-364
Range on HMM: 502-518/835
Sequence Identity: 52% (9 aa)

LYIQMELCSARSLRHLI
.|||||||    .| .|
FYIQMELCHYTTARYII
Kinase LmjF11.0060.AA Pkinase_Tyr 424-440 41 1.058604 3.0 Pfam 145-161 (270) Show / Hide 
Range on Protein: 424-440
Range on HMM: 145-161/270
Sequence Identity: 41% (7 aa)

SEAGIIRVADFGLARVM
.| ......|||||| .
TENNVVKICDFGLARDI