Gene LmjF36.6090 (L.major)
LmjF36.6090
Species: L.major
Alias: LmajK160, LmjF36.6090
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF36.6090.AA | Protein | None | 532 | None | Fasta, JSON |
| LmjF36.6090.kin_dom | Protein Kinase Domain | None | 304 | None | Fasta, JSON |
Protein domains of LmjF36.6090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| ABC1 | LmjF36.6090.AA | ABC1 | 157-277 | 36 | 8.8e-34 | 115.87 | Pfam | 1-126 (126) | Show / Hide |
Range on Protein: 157-277 Range on HMM: 1-126/126 Sequence Identity: 36% (46 aa) EELRCDPLTVFESVQRETVGSGSIGQVHLAKLKNSNRKVVVKVMHPDIIETIVLDFTILDNMAKKVDAWFPHL--ARYRLPSLSLAFTTHLAAQLDFRME ||| |.. .|.. .| ....||.||| |.||.. ..|.||| ||.. ... .|. .. |||.|. .||. |..| . | |. ||.| | EELGCPWEEIFQEFDEEPIAAASIAQVHRARLKDDGEEVAVKVQHPGVKKRMMRDIYNMRWMAKWVKRFFPGYRRQRFDLMWIVDEFRKNLPWELDYRRE AQNLERFRENFKSE---RYVEFPEPL |.| |||||||. .| |. AKNMERFRENFRHWHRQPWVYVPKVY |
|||||||||
| Kinase | LmjF36.6090.AA | ABC1-C | 195-339 | 37 | 1.9e-27 | 82.51 | In-house | 1-146 (307) | Show / Hide |
Range on Protein: 195-339 Range on HMM: 1-146/307 Sequence Identity: 37% (55 aa) VVVKVMHPDIIETIVLDFTILDNMAKKVDAWFPHLARYRLPSLSLAFTTHLAAQLDFRMEAQNLERFRENFKSERYVEFPEPL--MSTQRMLVETFCEGE | |||.|| .. . .| .| . .| | . || . | . |.| | |||||| | ||. . | || || | .||||. | VAVKVLHPGLLAQVHMDL-LLMKIGSRVLGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEESV PANPEFLASLPPHARDVLANKGLNTWCKMLLRDNFIHGDMHPGNILI | | .| . .| |.| ||. |||.| |.||||||. PVSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILV |
|||||||||
| Kinase | LmjF36.6090.AA | ABC1 | 157-277 | 30 | 3.9e-24 | 86.49 | In-house | 1-123 (123) | Show / Hide |
Range on Protein: 157-277 Range on HMM: 1-123/123 Sequence Identity: 30% (38 aa) EELRCDPLTVFESVQRETVGSGSIGQVHLAKLKNSNRKVVVKVMHPDIIETIVLDFTILDNMAKKVDAWFPH--LARYRLPSLSLAFTTHLAAQLDFRME ..|. . ||.. . ... ||.|||.|||| ..|.|||.||.. | | | . . | .|. || . ..|. .. | . |. ..||. | QDLG-NWEDVFSEFDEKPFAAASIAQVHRAKLKD-GQTVAVKVQHPGVREQIHYDINNMEMVVKMCDWFFPGPDFKWFFLMWFVDEFQKELPWECDFNNE AQNLERFRENFK--SERYVEFPEPL |.|.|..|..|| ....|... ARNAEKCRQLFKKFHWPFFYVPRIH |
|||||||||
| Kinase | LmjF36.6090.AA | ABC1-B | 157-266 | 28 | 1.8e-14 | 49.59 | In-house | 1-111 (125) | Show / Hide |
Range on Protein: 157-266 Range on HMM: 1-111/125 Sequence Identity: 28% (32 aa) EELRCDPLTVFESVQRETVGSGSIGQVHLAKLKNSNRKVVVKVMHPDIIETIVLDFTILDNMAKKVDAWFP---HLARYRLPSLSLAFTTHLAAQLDFRM . |. . ||. . ... |. |||.|||. . | |||.||.. . . .| . . | .|. || ... .. . |. ||| KDLG-NIEDVFSEFDQKPIAAASLAQVHRAKLHD-GETVAVKVQHPWLRKQFHYDMMMMELFVKVCDWFFPKSPDFKEFPFMWFHDEIQKNLPQELDFYN EAQNLERFRENFK || | |. |. || EARNAEKCRQMFK |
|||||||||
| Kinase | LmjF36.6090.AA | CAMK | 174-200 | 30 | 5e-06 | 14.59 | In-house | 1-39 (425) | Show / Hide |
Range on Protein: 174-200 Range on HMM: 1-39/425 Sequence Identity: 30% (12 aa) TVGSGSIGQVHLAKLKNSN------------RKVVVKVM | |.|| |.|.|.. ||.. .|| .|.. TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKII |
|||||||||
| Kinase | LmjF36.6090.AA | S_TKc | 169-477 | 11 | 1.8e-05 | -96.77 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 169-477
Range on HMM: 1-231/231
Sequence Identity: 11% (41 aa)
SVQRETVGSGSIGQVHLAKLKNSNRKVVVKVMHPDIIETIVLDFTILDNMAKKVDAWFPHLARYRLPSLSLAFTTHLAAQLDFRMEAQNLERFRENFKSE
...|.|. |.|.... |...|.| .|... ..| | | |..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------------------------------EHIRREIQILKK--HHPNIV
RYVEFPEPLMSTQRMLVETFCEG---EPANPEFLASLPPHARDV-----LANKGLNTWCKMLLR-------DNFIHGDMHPGNILIDCTSDPHEPTVTMI
.. .. . . .| .|.| . | .. . . . ... ... ..|| | | |||.| .. .
KLYDVFQD---DHLYMVMEYCDGDLGD------LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKIC
DVGLCQQLTEHEGAVTHDLM--ESFVRWNSNQCAD----------SLFAMSD-SQPYADADLFRRDLADLFKHFRPTRNDENAVTNILQSVFESIRQNNV
| ||. || . .| . | | . . |. | |. ... .||. .
DFGLARQL--TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYEMLCGYPPFP-------QMQMMFKKIG-------------------------
QMDPAYVSLLFAVLVLESFIMNLN--PDFNMVRH------TAPWL
| . .. . .. . | . . ||.
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
|
|||||||||
| Kinase | LmjF36.6090.AA | TKL | 175-201 | 25 | 3.4e-05 | 14.66 | In-house | 1-35 (364) | Show / Hide |
Range on Protein: 175-201 Range on HMM: 1-35/364 Sequence Identity: 25% (9 aa) VGSGSIGQVHLAKLKNSN--------RKVVVKVMH .|||. |.|. .|... . . |.||... IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFK |
|||||||||
| Kinase | LmjF36.6090.AA | CAMKL | 167-205 | 30 | 8.8e-05 | 11.03 | In-house | 1-38 (297) | Show / Hide |
Range on Protein: 167-205 Range on HMM: 1-38/297 Sequence Identity: 30% (12 aa) FESVQRETVGSGSIGQVHLAKL-KNSNRKVVVKVMHPDII .. .. | | || |.| ||. .. ..|| .|... . | YRIGK--TLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKI |
|||||||||
| Kinase | LmjF36.6090.AA | Aur | 176-201 | 38 | 0.000103 | 7.81 | In-house | 8-33 (257) | Show / Hide |
Range on Protein: 176-201 Range on HMM: 8-33/257 Sequence Identity: 38% (10 aa) GSGSIGQVHLAKLKNSNRKVVVKVMH | |. |.|.||. |... .. |||. GKGKFGNVYLARHKKTHFIFALKVMF |
|||||||||
| Kinase | LmjF36.6090.AA | ABC1-A | 179-199 | 61 | 0.000108 | 12.47 | In-house | 10-29 (216) | Show / Hide |
Range on Protein: 179-199 Range on HMM: 10-29/216 Sequence Identity: 61% (13 aa) SIGQVHLAKLKNSNRKVVVKV ||||||.| || . |.|.||. SIGQVHQAVLK-DGREVAVKI |
|||||||||
| Kinase | LmjF36.6090.AA | ABC1-C | 424-473 | 28 | 0.000525 | 7.87 | In-house | 258-307 (307) | Show / Hide |
Range on Protein: 424-473 Range on HMM: 258-307/307 Sequence Identity: 28% (14 aa) VTNILQSVFESIRQNNVQMDPAYVSLLFAVLVLESFIMNLNPDFNMVRHT | .| ||| . |... . |. ||..||| | | .. VSSLLSSVFKLLMTHKVKLESNFASIVFAIMVLEGLGRSLDPKLDILEAA |
|||||||||
| Kinase | LmjF36.6090.AA | STE | 170-215 | 12 | 0.001182 | 8.92 | In-house | 1-82 (359) | Show / Hide |
Range on Protein: 170-215 Range on HMM: 1-82/359 Sequence Identity: 12% (10 aa) VQR-ETVGSGSIGQVHLAKLK------NSNRK---------VVVKVMH--------------------PDIIETIVLDFTIL .. | .|.|. |.|..|. . .... . .|.|. ..... | . |. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIM |
|||||||||
| Kinase | LmjF36.6090.AA | CK1 | 326-360 | 23 | 0.001688 | 8.17 | In-house | 152-198 (339) | Show / Hide |
Range on Protein: 326-360 Range on HMM: 152-198/339 Sequence Identity: 23% (11 aa) NFIHGDMHPGNILIDCTS-----------DPHEPTVTMIDVGLCQ-Q .||| | |.|.... . .. . .| ||| |.. . GFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRK |
|||||||||
| Kinase | LmjF36.6090.AA | CK1 | 176-199 | 22 | 0.05191 | 2.91 | In-house | 8-42 (339) | Show / Hide |
Range on Protein: 176-199 Range on HMM: 8-42/339 Sequence Identity: 22% (8 aa) GSGSIG-QVHLA-----KLKNSN-----RKVVVKV |.|. | |.... | ...| ....|| GEGGFGYQIYKVQKEDHKDMKNNKPYKGEEYAMKV |
|||||||||
| Kinase | LmjF36.6090.AA | STE | 328-364 | 37 | 0.104918 | 1.95 | In-house | 174-200 (359) | Show / Hide |
Range on Protein: 328-364 Range on HMM: 174-200/359 Sequence Identity: 37% (14 aa) IHGDMHPGNILIDCTSDPHEPTVTMIDVGLCQQLTEH || | |.|||. | .| |.| |||.. IHRDIKPANILL----------VKLCDFGVCGQLTDS |
|||||||||