Gene LmjF36.4550 (L.major)

LmjF36.4550

Species: L.major
Alias: LmjF36.4550, LmajK163
External Links:
Annotation: Secondary Group: PKL, Third Group: PKL, Secondary Family: Alpha, Third Family: Alpha, Secondary Subfamily: Alpha-Kineto1, Third Subfamily: Alpha-Kineto1

Classification

Group: PKL
Family: Alpha
Subfamily: Alpha-Kineto1

Sequence

Name Sequence Type Origin Length Description Download
LmjF36.4550.AA Protein None 1141 None Fasta, JSON
LmjF36.4550.kin_dom Protein Kinase Domain None 237 None Fasta, JSON
LmjF36.4550.kin_dom2 Protein Kinase Domain None 240 None Fasta, JSON
LmjF36.4550.kin_dom3 Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of LmjF36.4550.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Alpha_kinase LmjF36.4550.AA Alpha_kinase 164-382 22 7.9e-51 177.16 Pfam 1-225 (225) Show / Hide 
Range on Protein: 164-382
Range on HMM: 1-225/225
Sequence Identity: 22% (55 aa)

IHQDKYFATFAVELL--DLVKPATPMLAKVYRH----NID---LVSETDYYSLGQAQALCEEFARDYTRTAARSHYVKFHLPLLTNRVVVRLDMDSVLDP
..| .... | .. .  .  .. ... ||.|..    |..   .|.| .| . ...|..|....... ... ...  ....  .   .|..|. .. .|.
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC

AIRTARKGFFSYRTQDTRQVMFLMEPNTVACEALGI-SFASREVDEGKCYSRGDAMWSRDIYRDIADGFSHFTYVRSRMCMVAHGFMRSN--G---YLLD
..     ||||||| |.......|||.      . .  |    .  |..|   |.|. .| . ...  ||||||.||. .|. .     .  .   || |
YQ-----GFFSYRT-DWGGKYWYMEPY------IEGCEFVKYNNNYGWVY---DNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTD

PLFHTTDSER---F--TMGDAGRSAMEDWVE-GHRCGDTC
|  ||.|...   |  .||. |  ..| ...  |.| ..|
PQIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase LmjF36.4550.AA Alpha_kinase 145-382 19 4.6e-09 18.95 SMART 1-255 (255) Show / Hide 
Range on Protein: 145-382
Range on HMM: 1-255/255
Sequence Identity: 19% (52 aa)

TRRWLAHHITVRV---LHHNRGIHQDKYFATFAVELLDLVKPATPMLAKVYRHNIDLVS-ETDYYS--------LGQAQALCEEFARDYTRTAARSHYVK
.  |.. ...|..   ..  .| .   | . .  | ... .. . . ||......  .  | .|.          ...| .|...|... . |. ..  .
DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQ-HNPCP

FHLPLLTNRVVVRLDMDSVLDPAIRTARKGFFSYRTQDTRQVM----FLMEPNTVACEALG---ISFASREVDEGKCYSRGDAMWSRDIYRD----IADG
 .   .   |....   . .  . .  ....|||||.|.. ||    |.|||       ..   . . ..  ..  |  ..    |    |     ..  
KKIDFIPCYVFHFPRR-IPA--EYDRNIPYWFSYRTTDQMMVMCCCIFHMEPF------MEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQA

FSHFTYVRSRMCMVAH---GFMRSNGY--LL-DPLFHTTD--SERFTMGDAGRSAMEDWVEGHRCGDTC
|||.||..|. .|.     |  ..||.  .. ||  ||.|   . | ||  |  ..| ... |.| . |
FSHWTYEWSNHQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase LmjF36.4550.AA Alpha 343-382 23 0.03033 2.02 In-house 170-215 (215) Show / Hide 
Range on Protein: 343-382
Range on HMM: 170-215/215
Sequence Identity: 23% (11 aa)

NGYLLDPLFHT----TDSERFTMGDAGRSAMEDWVEGH--RCGDTC
...| ||  |.      ...|  |. | ..|  .   |   | . |
EWKLTDPQIHCPAKLDQGMKFGDGNCGYEGMFRFFYTHHVQCNHYC
Kinase LmjF36.4550.AA VWL 343-387 30 0.130384 0.68 In-house 161-206 (206) Show / Hide 
Range on Protein: 343-387
Range on HMM: 161-206/206
Sequence Identity: 30% (14 aa)

NGYLLDPLFHTTDS-ERFTMGDAGRSAMEDWVEGHRCGDTCRALGI
.| | ||  |. |  ..|  |..| . |      | | . |. |  
DGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKYCQKLQL
Alpha_kinase LmjF36.4550.AA Alpha_kinase 646-713 32 2.3e-10 37.0 Pfam 147-225 (225) Show / Hide 
Range on Protein: 646-713
Range on HMM: 147-225/225
Sequence Identity: 32% (26 aa)

LRHVVDAFSHFTLHKSGNHLLVCHFKCQG--G---LLMHPNINTSSGCG---F--ETLNDGQAGIDAWAR-AHTCNDVC
. ... |||||| |.|.  ..||.    |  .   .|  | |.|  |..   |   . | || ||. .    | ||..|
WNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase LmjF36.4550.AA Alpha_kinase 486-713 21 1.3e-07 0.76 SMART 1-255 (255) Show / Hide 
Range on Protein: 486-713
Range on HMM: 1-255/255
Sequence Identity: 21% (56 aa)

RAKWMEVPMRLTVSASAVPDTVDGTYAFFAIEEEREG----GRPVPMRARFLLRPEARDA---DYYH--------FGDAYCVCVTLGQAFREYRASNVCA
. || . .... .     |    .    .  .. .|     ..   . |.  ...  |.    .|.|         . ....|  ....|   ...|.| 
DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQHNPCP

RELDFYAAYAVRVPQANIPDCIKAAVHDSDFFTRTTADSGDVM----FVAEP----EFQSFSPRCSPNADGVTEDAAGFDDLALRH----VVDAFSHFTL
   ||  .| .. | . ||        .. .|. .| |...||    |. ||    ||. .. ...   |          .   |.    .. ||||.|.
KKIDFIPCYVFHFPRR-IP--AEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQAFSHWTY

HKSGNHLLVCHFKCQGG--------LLMHPNINTSS--GCGFETLNDGQAGIDAWARAHTCNDVC
..|.  .|||    ||         ..  | | | .  | ||   | ||.||. ..  | ||..|
EWSNHQMLVCDI--QGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase LmjF36.4550.AA Alpha 652-713 30 0.000109 9.1 In-house 146-215 (215) Show / Hide 
Range on Protein: 652-713
Range on HMM: 146-215/215
Sequence Identity: 30% (21 aa)

AFSHFTLHKSGNHLLVCHFK-CQG-GLLMHPNINT----SSGCGFETLNDGQAGIDAWARAH--TCNDVC
||||.|  .|.  |.|.      | ..|  | | .    . |  | . | | .|.. ... |  .||. |
AFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEGMFRFFYTHHVQCNHYC
Kinase LmjF36.4550.AA Alpha-Unclassified 652-713 24 0.000467 8.94 In-house 144-215 (215) Show / Hide 
Range on Protein: 652-713
Range on HMM: 144-215/215
Sequence Identity: 24% (18 aa)

AFSHFTLHKSGNHLLVCHFKCQG--G-------LLMHPNINTSSGCGFE--TLNDGQAGIDAWARAH--TCNDVC
...|.|  ...  ..||    ||  .        .  | | |    ..   . | | ..|| |.  |   ||  |
TYQHWTYQWTNHCDIVCDL--QGWVDENDKKTWKMTDPQIHTIR-QRYQGFKTNCGMRFIDYWFNNHHVQCNHYC
Kinase LmjF36.4550.AA VWL 705-718 35 0.029616 2.63 In-house 193-206 (206) Show / Hide 
Range on Protein: 705-718
Range on HMM: 193-206/206
Sequence Identity: 35% (5 aa)

RAHTCNDVCKLLGM
. |.||. |. |  
MTHQCNKYCQKLQL
Alpha_kinase LmjF36.4550.AA Alpha_kinase 867-1101 30 9.2e-96 325.37 SMART 1-255 (255) Show / Hide 
Range on Protein: 867-1101
Range on HMM: 1-255/255
Sequence Identity: 30% (79 aa)

DFTWTPKRIFVRIVNPERGIGQGGMRVCFEVADVDPDT---CKESVMVAKMYRRTIKHVV-EKDYFM--------SVTVQKLSSLFAKDFNK--ERREGR
|  || ... |.| ..... ..|.||.|... |.. ..   | ....|||.... .|... |..||.        .| .| .. ..|..||.  . ....
DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQ-HNPC

PLLLNVLDSAVIALNRADLSAELLAKRTGFFSYRTEDTERVV----FCVEERLLGRFTKYNGNMGEAY-PTNECRLSPPAARERTMVFEAVEALSHYSLE
|     ....|. ..|. ..||   .....|||||.|...|.    |..|... | |.||| |.|... ... .. . .. | ||..||...| ||...|
PKKIDFIPCYVFHFPRR-IPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQAFSHWTYE

RSEGGLLVCDMQGV----RN--DLTDLEVHSYD--GQGLDMGNFGARGIEKFALRHRCTSVC
.|.. .||||.|||     .   .||  .|..|  |.|..|||.|..|||||. .|.| ..|
WSNHQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Alpha_kinase LmjF36.4550.AA Alpha_kinase 886-1101 30 7e-69 239.66 Pfam 1-225 (225) Show / Hide 
Range on Protein: 886-1101
Range on HMM: 1-225/225
Sequence Identity: 30% (73 aa)

IGQGGMRVCFEVADV-DPDTCKESVMVAKMYRR----TIK---HVVEKDYFMSVTVQKLSSLFAKDFNKERR--EGRPLLLNVLDSA-VIALNRADLSAE
..||.||.||.. |. ||.... ...|||.|.     ..|    |.|..||  . .| ..  ....||.. .  .  |  ....|.. |. |..    ..
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC

LLAKRTGFFSYRTEDTERVVFCVEERLLG-RFTKYNGNMGEAYPTNECRLSPPAARERTMVFEAVEALSHYSLERSEGGLLVCDMQGVR--N---DLTDL
..    ||||||| |.. .....|  . | .|.|||.| |..|          . . .. ......|.||.. .||.| ..|||.|||   |    ||| 
YQ----GFFSYRT-DWGGKYWYMEPYIEGCEFVKYNNNYGWVY---------DNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDP

EVHSYDGQG---LDMG--NFGARGIEKFAL-RHRCTSVC
 .|. ||..   .| |  |.| .|||||   .|.|. .|
QIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC
Kinase LmjF36.4550.AA Alpha 1040-1101 33 2.9e-21 57.14 In-house 146-215 (215) Show / Hide 
Range on Protein: 1040-1101
Range on HMM: 146-215/215
Sequence Identity: 33% (24 aa)

ALSHYSLERSEGGLLVCDMQ-GVR-NDLTDLEVHS-----YDGQGLDMGNFGARGIEKFALRH--RCTSVC
|.||.. ..|.| |.|.|.| ||   .|||  .|.      . ...| ||.| .|. .|.  |   |.. |
AFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGD-GNCGYEGMFRFFYTHHVQCNHYC
Kinase LmjF36.4550.AA VWL 1040-1106 33 7.1e-13 34.8 In-house 138-206 (206) Show / Hide 
Range on Protein: 1040-1106
Range on HMM: 138-206/206
Sequence Identity: 33% (23 aa)

ALSHYSLERSEGGLLVCDMQGVR-NDLTDLEVHSYDG-QGLDMGNFGARGIEKFALRHRCTSVCKSLNL
|.|| .   |.| ... |.||.    |||  .|  |  .    || |  |. .| . | |.  |..|.|
AFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKYCQKLQL
Kinase LmjF36.4550.AA Alpha-Unclassified 1042-1101 25 2.6e-12 36.3 In-house 146-215 (215) Show / Hide 
Range on Protein: 1042-1101
Range on HMM: 146-215/215
Sequence Identity: 25% (18 aa)

SHYSLERSEGGLLVCDMQG-VR------NDLTDLEVHSYDGQGLD--MGNFGARGIEKFALRH--RCTSVC
.|.. . . . ..|||.|| |         .||  .|. . |.     .|.| |.| ...  |   |   |
QHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIR-QRYQGFKTNCGMRFIDYWFNNHHVQCNHYC
Kinase LmjF36.4550.AA ChaK 995-1101 37 4.5e-09 32.12 In-house 120-219 (219) Show / Hide 
Range on Protein: 995-1101
Range on HMM: 120-219/219
Sequence Identity: 37% (42 aa)

FCVEERLLGRFTKYNGNMG-EAYPTNECRLSPPAARERTMVFEAVEALSHYSLERSEGGLLVCDMQGVRNDLTDLEV-HSYDGQGLDM----GNFGARGI
| .|. . | | ||| | | |  |||          |  |.     | ||.  |   | ||| |.|||   |||  |  .   |  ||     | |   |
FTIEKCMTGEFRKYNNNNGDEIIPTN--------TLEEIML-----AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAI

EKFALRHRCTSVC
  |  .| | | |
RNFRAKHHCNSCC