Gene LmjF34.3590 (L.major)
LmjF34.3590
Species: L.major
Alias: LmajK170, LmjF34.3590
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF34.3590.AA | Protein | None | 611 | None | Fasta, JSON |
| LmjF34.3590.kin_dom | Protein Kinase Domain | None | 315 | None | Fasta, JSON |
Protein domains of LmjF34.3590.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| PI3Kc | LmjF34.3590.AA | PI3Kc | 351-609 | 25 | 1.3e-83 | 285.04 | SMART | 1-336 (336) | Show / Hide |
Range on Protein: 351-609
Range on HMM: 1-336/336
Sequence Identity: 25% (87 aa)
AMIVKAGDDLRQEELALQLIHTFQCIWQEA----GLTVRVKPYAALPTHRDCGLLEVIEDSASMDSIKK-------------------------------
|.|.|.||||||.....|.. ... |||. .. ....||. .|| .||..|.. ..... .|.|
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM
-------------------------------ATRVSSIYNYYLKAYDGEDSVLYRKAQQNFVESMAGYSIICYILQIKDRHNGNLMIQ-RDGSLVHIDFG
.. . ..|.. .. . ... ...|. ||. |.|||....|||.|.||||.|.|. .| ..|||||
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPN-EDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
FLFVTSPGGLNF-----ESAPFKLSQELIDVMG--GASSDAFNYFRILVYEALAAARERCEDILTRVSILTPNNAMPCFGADPGAAVRQLRGRFRDDLLS
..| .|. . | | .||.| .....||| |. |. | ||| ....|. |.|. . |.. .... . |||. .. . ....|| ||| | ||
HIFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMM-EKDIKYLRQRFRLDHLS
EADYAVYAKE-----LIVNSADNWRTRRYDQFQSLQNG
. . | |.. ||..|.. | || |..|. ....
DEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
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| PI3_PI4_kinase | LmjF34.3590.AA | PI3_PI4_kinase | 348-556 | 19 | 4.9e-44 | 157.41 | Pfam | 1-300 (300) | Show / Hide |
Range on Protein: 348-556 Range on HMM: 1-300/300 Sequence Identity: 19% (58 aa) SMNAMIVKAGDDLR--QEELALQLI-----------------------HTFQCIWQEAGLTVR----VKPYAALPTHRDCGLLEVIEDSASMDSIKKATR . ..|.| ||||| |... .|.| .. .|. |.. | . || .|| .||..|..... ... | . .. WY-PFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYM VS-----------------------------------------SIYNYYLKAYDGED-SVLYRKAQQNFVESMAGYSIICYILQIKDRHNGNLMI---QR |. .. ... .... . . | .|||.|.||.... |||.. ||||.|.|. VKCKHKHFNKEHKMWMKMWPDWWHLMRMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWE-ARDNFVRSCAGMCVVDYILGNGDRHNDNIMVKDDKT DGSLVHIDFGFLFV--TSPGGLNFESAPFKLSQ------ELIDVMGG----ASSDAFNYFRILVYEALAAARERCEDILTRV-------SILTPNNAMPC .| |.|||||. | .... ..| ||.. . .....||| | .. || . ..|..| |. . ... ... ... . TGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDGLPMW FG RS |
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| Kinase | LmjF34.3590.AA | ATR | 434-546 | 23 | 9.6e-11 | 32.39 | In-house | 156-267 (267) | Show / Hide |
Range on Protein: 434-546 Range on HMM: 156-267/267 Sequence Identity: 23% (27 aa) DSVLYRKAQQNFVESMAGYSIICYILQIKDRHNGNLMIQR-DGSLVHIDFGFLFVTSPGGLNFESAPFKLSQELIDVMGGASSDAFNYFRILVYEALAAA |. . ...|.. |.| .... ||. . ||| |..|.. | .||.|. .| | ||.| . .. || .. || . . . DPQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGL--FRRACEVIMMCM RERCEDILTRVSIL |.. .||. . RDHRDDIMSVWDCF |
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| Kinase | LmjF34.3590.AA | FRAP | 444-483 | 51 | 3.2e-09 | 30.15 | In-house | 139-179 (251) | Show / Hide |
Range on Protein: 444-483 Range on HMM: 139-179/251 Sequence Identity: 51% (21 aa) NFVESMAGYSIICYILQIKDRHNGNLMIQRD-GSLVHIDFG |. |.| |.. ||| . ||| |.|.|| | .|||||| NYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFG |
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| Kinase | LmjF34.3590.AA | PIKK | 443-511 | 38 | 7.7e-09 | 28.69 | In-house | 187-257 (290) | Show / Hide |
Range on Protein: 443-511 Range on HMM: 187-257/290 Sequence Identity: 38% (27 aa) QNFVESMAGYSIICYILQIKDRHNGNLMIQRD-GSLVHIDFGFLFVTSPGGLNF-ESAPFKLSQELIDVMG .|. | | .. ||| . ||| |.||... | .||||||..| ..|.. | || | . ... || ENYTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVPEKVPFRLTRNMVNAMG |
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| Kinase | LmjF34.3590.AA | ATM | 448-511 | 40 | 1.1e-07 | 20.22 | In-house | 143-207 (304) | Show / Hide |
Range on Protein: 448-511 Range on HMM: 143-207/304 Sequence Identity: 40% (26 aa) SMAGYSIICYILQIKDRHNGNLMIQRDGS-LVHIDFGFLFVTSPGGLNFESAPFKLSQELIDVMG |.| ||. ||| . ||| |..| ||||| | | | ||.| ...| || SVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMG |
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