Gene LmjF30.1850 (L.major)
LmjF30.1850
Species: L.major
Alias: LmajK171, LmjF30.1850
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| LmjF30.1850.AA | Protein | None | 1374 | None | Fasta, JSON |
| LmjF30.1850.kin_dom | Protein Kinase Domain | None | 152 | None | Fasta, JSON |
Protein domains of LmjF30.1850.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| FYVE | LmjF30.1850.AA | FYVE | 451-531 | 28 | 1.7e-16 | 59.13 | Pfam | 1-71 (71) | Show / Hide |
Range on Protein: 451-531 Range on HMM: 1-71/71 Sequence Identity: 28% (24 aa) PSWQKDDESSDSCPSCGRAFISLSRPLGTRAHHCRSCGIRLC--VFCITRRAHYSFAKLAKPGSSDEAEERLVCDTCYKEYET | ||.|.|. ..|..|...| .. |.| ||||.|| | | .... . . | .... . ||| ||.... PHWQPDSEV-THCMICQKPF-TFF---GRRRHHCRHCGRIFCDDSKCSSHKC-IPH-----PPYYGWNKPVRVCD-CYDDLQK |
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| FYVE | LmjF30.1850.AA | FYVE | 448-531 | 28 | 2.3e-14 | 54.95 | SMART | 1-81 (81) | Show / Hide |
Range on Protein: 448-531 Range on HMM: 1-81/81 Sequence Identity: 28% (25 aa) LHNPSWQKDDESSDSC-PSCGRAFISLSRPLGTRAHHCRSCGIRLCVFCITRRAHYSFAKLA-KPGSSDEAE--ERLVCDTCYKEYET ..| || .||..|.| . |. | . .| |||| || .| .| ...... . . . |.| .. . |||.|| .. . ETKPHWQ-PDEEVDHCCMNCRKEFNF----VTNRRHHCRHCGRIFCSKCCNKWIPLPYMGNYKKNGN-NQ-NFTPVRVCDDCYEMMHH |
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| Kinase | LmjF30.1850.AA | ATR | 1132-1179 | 36 | 2e-06 | 17.64 | In-house | 166-215 (267) | Show / Hide |
Range on Protein: 1132-1179 Range on HMM: 166-215/267 Sequence Identity: 36% (18 aa) NFLASAKLFLLLNYIFSIGDRHKGNVLIGT-NGALLHIDFRFIFSE-KTF |.. | . .. || .|||| |.|| || . |.|. || . ..| NYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQF |
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| Kinase | LmjF30.1850.AA | FRAP | 1051-1102 | 36 | 0.000129 | 13.05 | In-house | 1-57 (251) | Show / Hide |
Range on Protein: 1051-1102 Range on HMM: 1-57/251 Sequence Identity: 36% (21 aa) EYMFLYK-RENVERD----QLMCISSRLLQMLLSSEIGNAEMLDYSVLPLSCDSGLI ||.|| | .| . | || . |||. .. | . ||..||| ..||| EYHFLLKGHEDIRQDERVMQLFGLINRLLHNNPETQKKNLSIQRYSIIPLSMNTGLI |
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| Kinase | LmjF30.1850.AA | PI3Kc | 1053-1369 | 11 | 0.000247 | -97.78 | SMART | 1-336 (336) | Show / Hide |
Range on Protein: 1053-1369
Range on HMM: 1-336/336
Sequence Identity: 11% (46 aa)
MFLYKR-ENVERDQLMCISSRLLQMLLSSE----IGNAEMLDYSVLPLSCDSGLIEKA-EGRELSNLD-------------------NM-----------
...| . .|..|. || . ..... . | |...|.. ..|.|| . | .. .|
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM
------------------------------------DIASY-VLHRGTRSCINFLASAKLFLL-------LNYIFSIGDRHKGNVLIG-TNGALLHIDFR
... . . | .. . ... .. . | . ||. ||||| .| .. ..| ..||||
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPN-EDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFG
FIFSEKTFVEKL-ARSTVRIDDAFLAAVEQCQQRQCSCFAGSSPAATSSHAQGWASPPASSGSGGRGSCASPTKAPEPSSAEIREAFFSSAAEWFVHVRP
.||. . .. . ||. .|.|
HIFGHGPKKPGFKHH-H------------------------------------------------------------------RERVPFRLTHDMVYVMG
----FAAVFYELWLYAVHRHTVPYNDAEMLNMLNTLFDRHASQTSSASK-FSTTMK-ESVNVCRLKDVTH--SSAEVLRTFAD----QVSRRVSESSVDA
. .| . . .... .. ... . | .. ... .. .|. ..... | . | |... |.. .. . || .
GGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMM-------VYDPIMPCWRMMEKDIKYLRQRFRLDHLSDEEAAQYFMQTMCTKLIEHSNESWTTR
MKMMGSMWSSW
|. | |
MYWMFHNWAQY
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| Kinase | LmjF30.1850.AA | PI3_PI4_kinase | 1145-1174 | 45 | 0.000473 | 16.68 | Pfam | 179-211 (300) | Show / Hide |
Range on Protein: 1145-1174 Range on HMM: 179-211/300 Sequence Identity: 45% (15 aa) YIFSIGDRHKGNVLI---GTNGALLHIDFRFIF ||. .|||| .| .. |.| | |||| ..| YILGNGDRHNDNIMVKDDKTTGHLFHIDFGHCF |
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| Kinase | LmjF30.1850.AA | PIKK | 1145-1174 | 45 | 0.000564 | 10.79 | In-house | 201-231 (290) | Show / Hide |
Range on Protein: 1145-1174 Range on HMM: 201-231/290 Sequence Identity: 45% (14 aa) YIFSIGDRHKGNVLI-GTNGALLHIDFRFIF || .|||| |..| ..| ..||||...| YILGLGDRHPENIMIDMQTGEIVHIDFGCCF |
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| Kinase | LmjF30.1850.AA | FRAP | 1145-1170 | 44 | 0.011901 | 5.74 | In-house | 152-178 (251) | Show / Hide |
Range on Protein: 1145-1170 Range on HMM: 152-178/251 Sequence Identity: 44% (12 aa) YIFSIGDRHKGNVLIG-TNGALLHIDF || .|||| |... | ..|||| YILGLGDRHPSNIMLQRYTGKIVHIDF |
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| Kinase | LmjF30.1850.AA | PIKK | 1090-1103 | 64 | 0.336103 | 0.58 | In-house | 74-87 (290) | Show / Hide |
Range on Protein: 1090-1103 Range on HMM: 74-87/290 Sequence Identity: 64% (9 aa) YSVLPLSCDSGLIE ||| |.| .|||| YSVIPMSQRCGLIE |
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