LmjF06.0640

Species: L.major
Alias: LmajK193, LmjF06.0640
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF06.0640.AA Protein None 3142 None Fasta, JSON
LmjF06.0640.kin_dom Protein Kinase Domain None 2467 None Fasta, JSON

Protein domain

Protein domains of LmjF06.0640.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF06.0640.AA S_TKc 2701-3023 20 8.8e-64 219.13 SMART 1-231 (231) Show / Hide
Range on Protein: 2701-3023
Range on HMM: 1-231/231
Sequence Identity: 20% (70 aa)

KIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNSAYFNILLEFVPG--GS
    . .|||. ..||....   |.. |.|...                       .... ||..|.|  |||||..|.. |.  .. . .|...|  |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----------------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGD

LRHLLDNFGA------LSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLLNRPHATAARGGGGEAQSVTSRTTPGQRKDD
|...... |       ... .. .|..| ...|.|.|.|.|.| | | .|||..|   .|..||| ||.|                              
LFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------

VVSAGAGGTLHIAGTLRWMDPALFHNPHSSGAADVTAAVAAKDSSNKLGGPTK-AGDIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTAEPPEIP
          .. ||. .| | ..                         | .| . |.||.||...||..|. |.       .... ...          
---------TTFCGTPWYMAPEVL-------------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG---------

ECPECPDLVTIAQTCLKMDPAQRPTCEELLR----------I
     |..  . . ||..||..|||. |.|.          .
----SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LmjF06.0640.AA STE11 2700-2863 36 1.8e-55 190.64 In-house 1-168 (303) Show / Hide
Range on Protein: 2700-2863
Range on HMM: 1-168/303
Sequence Identity: 36% (64 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRL-PTFAHGSDAEQDPEAKAILQQ---YRSLQEEISVLSKATHPNIVQYYGSSQ---NSAYFNILLE
|. | |..|||    ||...|. .|.|.||| ... ..          .... ..|.    . .||||.....  |.|||.|||...      ..|| .|
WQKG-EIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQM------KEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFME

FVPGGSLRHLLD-NFGA--LSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGK-VKLTDFGTARLLN
..|||||...|. ..|.  ..  ||  |..| ||||.||| |.|.| | |.||||.  .|  .||.|||.|. |.
YCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLA

Kinase LmjF06.0640.AA STE11-Unclassified 2700-2860 40 5.1e-54 185.78 In-house 1-155 (308) Show / Hide
Range on Protein: 2700-2860
Range on HMM: 1-155/308
Sequence Identity: 40% (66 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSS--QNSAYFNILLEFVPGG
|. | |..|||.  .||...|...|...||| .. .         |..... .   . |.|.|..|| .  |.||||||| .  .     || .| .|||
WQKG-EFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNS-----QQEDMQKE--MIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGG

SLRHLLDNFGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTAR
|.. .|...|...  ||  |. | |||||||| |.|.| | |.|||||  .| .||||||.|.
SIWSMLNKYGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAK

Kinase LmjF06.0640.AA TKL 1168-3024 3 1.6e-41 144.25 In-house 55-364 (364) Show / Hide
Range on Protein: 1168-3024
Range on HMM: 55-364/364
Sequence Identity: 3% (69 aa)

YEGLPGAATTAASQGGFSSTGRHLLPPPPSPSEEFASSAHRRQRSPNTAALSAAAAVGTVPDGEVASNGFAPPPVKSTSPTTAVLLLSSQQTASTAFSPL
|                                                                                                   
Y---------------------------------------------------------------------------------------------------

HNARLQRQHGGAGSPTFVDQASPPPHAAGLYGTFTVAASQQHRDTPLPGFFYVPCTRAAAALADVPLSAAGHSGELATTSASGGGGARPSSASSTSGGPH
                                                                                                    
----------------------------------------------------------------------------------------------------

QISSLQLPWSLAGRVGTAAAASGHADRLSSQLSTASQSPLSFGVDGGGGGNKNSTSGVAVGVRCPRPPPPPPLAAGLERGTDPYAEAGVATAFETDGDKE
                                                                                                    
----------------------------------------------------------------------------------------------------

AQGDGDEDVMAAPYCSSPVMVHGLLFRATLRPLRGVLCSEEGGVVENQLGGPLRTSASAVEGKHTGGCGAEGNPFFNQPPRAAVEGEDAEEGQALARKNT
                                                                                                    
----------------------------------------------------------------------------------------------------

QAYDDDKSGDDNSGEALLSERQPHHRDHRLHRTAAGARMRSSECQKDSGAEDQSVMDDDDDDDTPFDEDDLPKAMAGTMSGGPTLAATLEQLFATKAMAC
                                                                                                    
----------------------------------------------------------------------------------------------------

NFGLDKESAAGPRCSAASTVTTTATAASGALLSSELLPQYSLREALKQLAASESPLLLTFSEPPVYATACASAEALLQERRLSHRRVSSASLDEHGHSGV
                                                                                                    
----------------------------------------------------------------------------------------------------

LTHANDNGVAAAASGGGCTSGVPESYLGTPLVPFLRRQRPQVPALWGDGSASLKFVAAVKEAVDSYRESIEEDSSGYTDLLGLLSLSGGNDGCCPSSGYA
                                                                                                    
----------------------------------------------------------------------------------------------------

ARNSASSLTPTSFGGAPDAAVTTAITADAVRQLRLLKSLSDHLLQATAAYNRTRQSMSFATYGLSGGDGGGGGVAARVSPSSSASSPPSLLLGLFAAPSV
                                                                                                    
----------------------------------------------------------------------------------------------------

PDADAAHERHLHARRPRSAKTPSPYKDRPAGGPLGVSVHQSPFQPPPPPPQLAFTAEEPGGAHRRLQGDGSHWRQPGEPAASASTGGSGAHTGIYRDPNS
                                                                                                    
----------------------------------------------------------------------------------------------------

TPFSVASEDVTGVAPSAVGDSRNWALKEPPPPPHRGATRPRGSGGRRDIQDGGVSPVKSRPRHAAKSSTASAPLKASRGRHTGARHGRRGGAGASTPAPS
                                                                                                    
----------------------------------------------------------------------------------------------------

PPLVPLDAAVDVTKELRSFGYMAEISGSTPPSASPCGGGGSGRTAAAAPAAMSSLNASTLVAAGSEPAMSTPRPHATGTGASALDVATPQTELHPSPRRC
                                                                                                    
----------------------------------------------------------------------------------------------------

DTVVTSGEGEASGGGGGAGEDAAAAGGVASRLATSPRYRGSLLLSPSLATAEMGELEASYGTESRHQQPQHRSSPNIISGAGSGSGATAAMRDASPRRCS
                                                                                                    
----------------------------------------------------------------------------------------------------

SAVYRRESSLDVLPSAPVGSGSFRGNGGLVPSSSSVSLSAGAGAGGQGTGSPSPHPARTGSGSLNANATATAAATAAVRSTPRRPGEGAVWAVLVSRDEA
                                                                                                    
----------------------------------------------------------------------------------------------------

TIPSCCISVNLGDEFRLGRSSKCTAVVSDSFVSSTQFSIVRTVSASTTAQDLCPGSGRSERGSRRSKAFTVTLYDRSANGTYVNVKKLGKDKSCVLRDKA
                                                                                                    
----------------------------------------------------------------------------------------------------

LITFRLSTSQFFLGFVFMLTDERGVPLDDRTGMGGGSGLRSLLDARLSPQPQTGRRTNASSAGGGGKESSSSQNTVMASPTALSTSAARRNTPRAVSTPD
                                                                                                    
----------------------------------------------------------------------------------------------------

NSSFASGTPNGSRRAGGGAPRSSRHAHRETIEWKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLS
                                                                         ||     ... . .    . ||| ..|
-------------------------------------------------------------------------SD-M-QLNDPEASWFRFFEEEEIMMMS

KATHPNIVQYYGSSQNSAY-------------FNILLEFVPGGSLRHLLDNFGALSPGVILSYVHQALEGLAYLHRHN--------IVHSDFKAANILIT
.  ||||||..|..... .             . |  |..|||||.|.|       . .... ....  |..||| .|        |.| | | .|||. 
RLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVD

EKGK--------------VKLTDFGTARLLN---------------RPHATAARGGGGEAQSVTSRTTPGQRKDDVVSAGAGG--TLHIAGTLRWMDPAL
|...              .|..|||..| ..               .                     .        ..  ..  | .. ||.||| | .
ENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESA---------------------E--------HQ-NNRKTTMTQCGTPRWMAPEV

F----HNPHSSGAADVTAAVAAKDSSN-KLGGPTKAGDIWSVGCTMIEMMSGEAPWFEYDFESEE------QIVNLLTYTAEPPEIP-----------EC
.     ... .|.          |    | .  ... |..| |  . |..... |...|......      ..  .  .  ..|.||           . 
LRGQMNYTEKVGI----------DE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCP

PECPDLVTIAQTCLKMDPAQRPTCEELLRIV
.  |..  ..| | ..|| .||...|.| . 
DCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Kinase LmjF06.0640.AA STE 2701-2863 26 8.4e-41 141.81 In-house 27-224 (359) Show / Hide
Range on Protein: 2701-2863
Range on HMM: 27-224/359
Sequence Identity: 26% (56 aa)

KIGEEMLGKGGNAEVYLGINLT---------------NGQLIAVKRVRLPTF-----AHGSDAEQDPEAKAI-----LQQYRSLQEEISVLSKAT--HPN
  | |..|||.  .||...|                 .|...|.|...| .             | .. .        ..  ....||....|    |||
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDEN------Q-EN-Q-ELENKNHEEMQQILKEIKIMKKCNHMHPN

IVQYYGSSQNSA-------YFNILLEFVPGGSLRHLLD-NFGALSP-------------GVILSYVHQALEG-LAYLHRHNIVHSDFKAANILITEKGKV
||.|||.  .         . .| .|...||||. ... ..| . |              .|  ...| |.| |.|||.|.|.| | |.||||.     |
IVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----V

KLTDFGTARLLN
||.|||..  |.
KLCDFGVCGQLT

Kinase LmjF06.0640.AA MEKK15 2700-2862 41 7.7e-39 135.36 In-house 1-151 (264) Show / Hide
Range on Protein: 2700-2862
Range on HMM: 1-151/264
Sequence Identity: 41% (67 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNSAYFNILLEFVPGGSL
|| | ..||||    || |.  | ||||||| | | .           . ..  |||| ||||. .|    | ||| | | . .    || ..||||||.
WKKG-NILGKGAYGTVYCGLTNT-GQLIAVKQVELDEI----------DKEKAKQQYRKLQEEVDLLKTLKHKNIVAYLGVCLEDNVVNIFMQFVPGGSI

RHLLDNFGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLL
  ..  ||.|   |   | .| |.| .|||  ..|| | | .|...   | .|| ||| |. |
SSIINRFGPLDEMVFCKYTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRL

Kinase LmjF06.0640.AA Dicty2 2755-2859 42 1.8e-37 128.09 In-house 46-153 (264) Show / Hide
Range on Protein: 2755-2859
Range on HMM: 46-153/264
Sequence Identity: 42% (46 aa)

QYRSLQEEISVLSKATHPNIVQYYGSSQNSAYFNILLEFVPGGSLRHLLDNFGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGK---V
|  |.  ||  | |  |.||| |... ..... .| ||.. .|||.  . .|| ..   .  |. | |.||.||||  ..| | ||||||||  ||   .
QHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCFPESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVI

KLTDFGTA
||.|||.|
KLADFGVA

Kinase LmjF06.0640.AA Pkinase 2700-2911 21 1.5e-36 130.3 Pfam 1-178 (293) Show / Hide
Range on Protein: 2700-2911
Range on HMM: 1-178/293
Sequence Identity: 21% (49 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSD-----AEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNSAYFNILLEFV
..||.  .|.|. ..||....  .|.. |||......  .. |     .                  ||... .  |||||..|.. ... .  . .|..
YHIGRK-IGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYC

PGG----SLRHLLD--NFGAL--SPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKV----KLTDFGTARLLNRPHATAARGGGGEAQSVTS
.||    .| ...   . |..  |. .. .|. | |.||.|.|...|.| | | .|||| ..| .    |..||| |....                   
EGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------------

RTTPGQRKDDVVSAGAGGTLHIAGTLRWM
                . . ...||...|
------------Y-NNS-MTTFCGTPWYM

Kinase LmjF06.0640.AA MEKK2 2700-2862 37 7.9e-32 112.06 In-house 1-153 (262) Show / Hide
Range on Protein: 2700-2862
Range on HMM: 1-153/262
Sequence Identity: 37% (62 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNSA--YFNILLEFVPGG
|. |  .||.|    ||.      |  .||| |.            ||.     .  ..|. || .|    |. ||||||  .. .     | .|..|||
WRRG-KLLGQGAFGRVYVCYDVDTGRELAVKQVQF-----------DPDNPETRKEVQALECEIQLLKNLQHERIVQYYGCLRDNQEKTLSIFMEYMPGG

SLRHLLDNFGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLL
|..  |  .|||   |   |  | |||..||| | ||| | | ||||    | ||| ||| .. |
SVKDQLKAYGALTETVTRKYTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRL

Kinase LmjF06.0640.AA ASK 2706-2864 36 6.4e-31 99.94 In-house 1-147 (254) Show / Hide
Range on Protein: 2706-2864
Range on HMM: 1-147/254
Sequence Identity: 36% (59 aa)

MLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNSAYFNILLEFVPGGSLRHLLD-
.||||    || | .. .   ||.| .                      . . |.|||.. ..  | ||||| |.  . .|| | .| ||||||  ||  
VLGKGTYGIVYAGRDMHTQVRIAIKEIPERDSR----------------YVQPLHEEIALHKQLRHRNIVQYLGCCSENGYFKIFMEQVPGGSLSALLRS

NFGALS--PGVILSYVHQALEGLAYLHRHNIVHSDFKAANILI-TEKGKVKLTDFGTARLLNR
 .| .      .  | .| |||| ||| ..||| | |  |.|. |  | ||. ||||.. | .
KWGPMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTCKRLAG

Kinase LmjF06.0640.AA STE20 2700-2864 28 9.7e-29 101.81 In-house 1-169 (288) Show / Hide
Range on Protein: 2700-2864
Range on HMM: 1-169/288
Sequence Identity: 28% (53 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQL----IAVKRVRL-----PTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGSSQNS----AY
... |. .|.|.  .||....  .|..    .|.|.. |     .              .   .. ...| |||....  |||||.|||| . .      
YELLEK-IGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNE--------------Q---DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDE

FNILLEFVPGGSLRHLLDNFG---------ALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLLNR
  |. |.  ||||. .....           ..   |    ...|.||.|||...|.| | ||.|||.||.|.|||.||| .  |..
LWIVMEYCGGGSLTDIMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTK

Kinase LmjF06.0640.AA STE-Unique 2787-2859 31 2.6e-20 68.39 In-house 369-457 (616) Show / Hide
Range on Protein: 2787-2859
Range on HMM: 369-457/616
Sequence Identity: 31% (28 aa)

FNILLEFVPGGSLRHLLDNFGA---------LSPGVILSYVHQALEGLAYLHRHN--IVHSDFKAANILITEKG-----KVKLTDFGTA
..| .|. ..|.|. .... |.         .    .. |  |.|||| |||     |.| |.|..||... .|     |||. |||.|
VWIFMEYCEHGTLQQIIKRCGCPGNPNNLQLFPETEVIWYTYQILEGLEYLHSQHNPIIHRDLKPHNIFCMQDGKGRVCKVKICDFGHA

Kinase LmjF06.0640.AA Pkinase_Tyr 2705-2862 27 1.1e-19 67.35 Pfam 5-161 (270) Show / Hide
Range on Protein: 2705-2862
Range on HMM: 5-161/270
Sequence Identity: 27% (47 aa)

EMLGKGGNAEVYLGINL----TNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQ--YRSLQEEISVLSKA-THPNIVQYYGSSQ-NSAY--FNILLEFV
..||.|   |||.|.       ...  ||| ..                .|  .|   ... .|......   |||||..||     .      | .|..
KKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLK---------------EGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYM

PGGSLRHLLDN----FGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLL
|.|.|.. | .     ..|..  .|.. .|  .|..||...|..| |  | |.|.||...|| .||| ||..
PHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI

Kinase LmjF06.0640.AA STE11-Unclassified 2948-3021 32 6.4e-16 52.96 In-house 220-303 (308) Show / Hide
Range on Protein: 2948-3021
Range on HMM: 220-303/308
Sequence Identity: 32% (28 aa)

DIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTAEPPEIPEC--PECPDLVT---------IAQTCLKMDPAQRPTCEELL
||||.|||.||| .|..||  .... ......    . ..|.|||   | | | .          . . |.. ||  |||  .||
DIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVC-DFISCWISQECKDFLRKCFQIDPKKRPTANQLL

Kinase LmjF06.0640.AA STE 2948-3023 24 9.3e-16 52.23 In-house 250-359 (359) Show / Hide
Range on Protein: 2948-3023
Range on HMM: 250-359/359
Sequence Identity: 24% (27 aa)

DIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTA-----------EPPEIPECPE------------------CPDLVTIAQTCLKMDPAQRPTCE
||||.|||.|||  |. ||...   .     .  .. .           .|| .|.  .                   |..    . ||..|| .||| .
DIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTAS

ELLR-----I
.||.     |
QLLKSEHPFI

Kinase LmjF06.0640.AA TyrKc 2704-3024 21 5.4e-15 19.72 SMART 4-280 (280) Show / Hide
Range on Protein: 2704-3024
Range on HMM: 4-280/280
Sequence Identity: 21% (74 aa)

EEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKA--THPNIVQYYGSSQNS-------AYFNILLEFV
...|| |   |||.|.     .  ||| ..  .                    . . .|.....|    |||||. ||    .           |..|..
GKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

PGGSLRHLL-DNFGALSPGVILSYVHQALEGLAYLHRHNIVHSDFKAANILITEKGKVKLTDFGTARLLNRP-HATAARGGGGEAQSVTSRTTPGQRKDD
|.|.|.. | .. . |..   ||. .|. .| .|||..|..| |  | |.|..|.. || .||| .| .    ..                       .|
PHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------------------ESKD

VVSAGAGGTLHIAGTLRWMDP-ALFHNPHSSGAADVTAAVAAKDSSNKLGGPTKAGDIWSVGCTMIEMMS-GEAPWFE---YDFESEEQIVNLLTYTAEP
. ..  ..  .    .||| | ..                       . |  | . |.|| | .| |... |. |. .     . | .......     .
YYRKKEHKGGKTMLPIRWMAPECI-----------------------NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRM

PEIPE--------CPECPDLVTIAQTCLKMDPAQRPTCEELLRIV
|  |.        ||  ... .| ..| . ||..||| .|. .. 
PQPPNDYPMSFVCCP--DEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LmjF06.0640.AA STE11 2948-3022 35 1.4e-13 45.76 In-house 220-299 (303) Show / Hide
Range on Protein: 2948-3022
Range on HMM: 220-299/303
Sequence Identity: 35% (28 aa)

DIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTAEPPEIPEC--P---ECPDLVTIAQTCLKMDPAQRPTCEELLR
||||.|||.|||..|  || .||...  ..    ..   .|.|||   |     ...  . . |.. ||  |||  .||.
DIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQ

Kinase LmjF06.0640.AA Pkinase 2944-3024 19 3.9e-11 40.47 Pfam 190-293 (293) Show / Hide
Range on Protein: 2944-3024
Range on HMM: 190-293/293
Sequence Identity: 19% (20 aa)

TKAGDIWSVGCTMIEMMSGEAPWFEY----DFESEEQIVNLLTY-TAEPPEIPECPEC-----------------PDLVTIAQTCLKMDPAQRPTCEELL
... |.||.||...||..|. |. .     .  .. |....  .   . ..  .|..                  ...  .   ||..||..|||.|..|
GPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQIL

RI--V
    .
QHPWF

Kinase LmjF06.0640.AA FHA 2482-2572 18 1.4e-10 44.02 Pfam 1-73 (73) Show / Hide
Range on Protein: 2482-2572
Range on HMM: 1-73/73
Sequence Identity: 18% (18 aa)

FRLGRSSKCTAVVS-DSF-VSSTQFSI-VRTVSASTTAQDLCPGSGRSERGSRRSKAFTVTLYD--RSANGTYV--NVKKLGKDKSCVLRDKALITFR
...||...|  |.. |.. ||  .. | ... .                         .... |   | |||.|  | ..........|..   |.| 
WTIGRDPDCDIVLDNDPSFVSRHHCEIRRYDNG-------------------------RWYIRDLGCSTNGTFVTGNGQRIQPGEPHRLHHGDRIRFG

Kinase LmjF06.0640.AA STE-Unique 2948-3026 26 2e-09 29.07 In-house 535-616 (616) Show / Hide
Range on Protein: 2948-3026
Range on HMM: 535-616/616
Sequence Identity: 26% (22 aa)

DIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTAEP--PEIPECPEC-PDLVTIAQTCLKMDPAQRPTCEELLRIVEE
|||| ||....| .|  || ..   .     ... ..  |  |  .. | | |... . ..||. .| .||. ..||. .  
DIWSLGCMCFHMCCGCPPWHQRYHMQAYIEMCIHIHCQPPQCPIENIPPKCQPEQQQFIEKCLERNPHHRPSAHQLLHHFWL

Kinase LmjF06.0640.AA STE-Unique 2702-2780 27 9.1e-09 26.67 In-house 1-69 (616) Show / Hide
Range on Protein: 2702-2780
Range on HMM: 1-69/616
Sequence Identity: 27% (22 aa)

IGEEMLGKGGNAEVYLGINLTNGQLIAVKRVRLPTFAHGSDAEQDPEAKAILQQYRSLQEEISVLSKATHPNIVQYYGS
....|.|.|.. .|.. .|  ..   |.| ..| .|   .|  |.|  . |       ..||  ... .|.||| |||.
NCQQMIGRGSFGNVHNCQNKKDCFRCAIKVIHLKQF---KDFNQEPLVNMI-------ISEIEIMKCLHHQNIVKYYGH

Kinase LmjF06.0640.AA ASK 2945-3022 34 4.1e-07 19.5 In-house 176-250 (254) Show / Hide
Range on Protein: 2945-3022
Range on HMM: 176-250/254
Sequence Identity: 34% (27 aa)

KAGDIWSVGCTMIEMMSGEAPWFEYDFESEEQIVNLLTYTAEPPEIPECPECPDLVTIAQTCLKMDPAQRPTCEELLR
|. ||||.||||.||  |  |..| . |..  .     |    |||||     .       | . || .|.. ..||.
KPADIWSFGCTMVEMATGKPPFHELG-EPQAAMFKVGMYKKH-PEIPEE-LSAECKNFILRCFEPDPCKRASAQDLLQ

Kinase LmjF06.0640.AA Dicty2 2700-2732 36 1e-06 19.19 In-house 1-33 (264) Show / Hide
Range on Protein: 2700-2732
Range on HMM: 1-33/264
Sequence Identity: 36% (12 aa)

WKIGEEMLGKGGNAEVYLGINLTNGQLIAVKRV
 .||.| .|||. . || | . . |.  | |..
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQI

Kinase LmjF06.0640.AA Dicty2 2946-2967 54 2e-06 18.76 In-house 189-210 (264) Show / Hide
Range on Protein: 2946-2967
Range on HMM: 189-210/264
Sequence Identity: 54% (12 aa)

AGDIWSVGCTMIEMMSGEAPWF
| ||||.|||.||.  |  | .
ACDIWSLGCTIIELLTGNPPYW

Kinase LmjF06.0640.AA MEKK2 2948-2970 52 4e-06 18.28 In-house 188-210 (262) Show / Hide
Range on Protein: 2948-2970
Range on HMM: 188-210/262
Sequence Identity: 52% (12 aa)

DIWSVGCTMIEMMSGEAPWFEYD
|.||.|||..||.    || ||.
DVWSIGCTVVEMLTEKPPWAEYE

Kinase LmjF06.0640.AA FHA 2481-2555 16 1.9e-05 25.37 SMART 1-49 (49) Show / Hide
Range on Protein: 2481-2555
Range on HMM: 1-49/49
Sequence Identity: 16% (13 aa)

EFRLGRSSKCTAVVSDSFVSSTQFSIVRTVSASTTAQDLCPGSGRSERGSRRSKAFTVTLYDRS---ANGTYVNVKKL
....||.| |  .......|  .. |.     ..                         . | .    |||||| ...
TWTIGRHS-CDIQLPHPSISRHHCQIR----DGD------------------------YIIDLGEHSTNGTYVNGRRV

Kinase LmjF06.0640.AA MEKK15 2945-2970 46 0.000109 12.96 In-house 186-211 (264) Show / Hide
Range on Protein: 2945-2970
Range on HMM: 186-211/264
Sequence Identity: 46% (12 aa)

KAGDIWSVGCTMIEMMSGEAPWFEYD
.  ||||.|||. ||  .  || . |
RKSDIWSIGCTVFEMATRKPPWADMD

Kinase LmjF06.0640.AA STE20 2948-2969 59 0.001472 9.22 In-house 209-230 (288) Show / Hide
Range on Protein: 2948-2969
Range on HMM: 209-230/288
Sequence Identity: 59% (13 aa)

DIWSVGCTMIEMMSGEAPWFEY
||||.| | |||  || | |..
DIWSLGITAIEMAEGEPPYFDM

Kinase LmjF06.0640.AA STE20 3005-3022 50 0.003287 7.93 In-house 267-284 (288) Show / Hide
Range on Protein: 3005-3022
Range on HMM: 267-284/288
Sequence Identity: 50% (9 aa)

TCLKMDPAQRPTCEELLR
.|| .||..||| ..||.
KCLQKDPEKRPTASQLLK

Kinase LmjF06.0640.AA Pkinase_Tyr 2948-3024 27 0.011054 9.71 Pfam 196-270 (270) Show / Hide
Range on Protein: 2948-3024
Range on HMM: 196-270/270
Sequence Identity: 27% (22 aa)

DIWSVGCTMIEMMS-GEAPWFEYDFESEEQIVNLLTYTAEPPEIPECPE--CPDLVTIAQTCLKMDPAQRPTCEELLRIV
|.|| | .| |... || |  .|   | |.......   .     .|||  .... .. . | . ||..||| .|.... 
DVWSFGVLMWEIFTYGEQP--TYPGMSNEEVYEYIYEDGYR---MPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL