Gene 91274.m00102 (T.vaginalis)

91274.m00102

Species: T.vaginalis
Alias: 91274.m00102, TvagK0316
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
91274.m00102.AA Protein None 980 None Fasta, JSON
91274.m00102.kin_dom Protein Kinase Domain None 189 None Fasta, JSON

Protein domain

Protein domains of 91274.m00102.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 91274.m00102.AA TKL 172-262 24 1.6e-25 88.87 In-house 237-364 (364) Show / Hide 
Range on Protein: 172-262
Range on HMM: 237-364/364
Sequence Identity: 24% (31 aa)

PNWTPPEIYKGK----------------PRDEKSDVFLFGFLLFELLTGYIPFQELSAEETQ---------RVICVSKKRPQIP------------STAP
|.| .||. .|.                . .||.||. || .|.|.||. .|....  .. .          ..|. ..|| ||            ...|
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCP

EPLKLLIKHCWSPKKINRPTFAEIYQLF
...| |...||...  .||.| || . .
PSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 91274.m00102.AA Dicty4 172-264 38 3.7e-23 74.22 In-house 181-277 (277) Show / Hide 
Range on Protein: 172-264
Range on HMM: 181-277/277
Sequence Identity: 38% (37 aa)

PNWTPPEIYKGKPRDEKSDVFLFGFLLFELLTGYIPFQ--ELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQL--FEL
| |. ||.  ..| .||.||. || .|.|.||. .|.|    . ..  | .|  | || ||.  | ..| ||. ||..  ..||.|.|| |    | 
PCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 91274.m00102.AA MLK 174-262 33 1e-22 75.74 In-house 199-291 (291) Show / Hide 
Range on Protein: 174-262
Range on HMM: 199-291/291
Sequence Identity: 33% (31 aa)

WTPPEIY---KGKPRDEKSDVFLFGFLLFELLTGYIPFQ-ELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQLF
|  ||.    .. . .||.||. .| .| |.||. .|.. .... .    . . ..|| ||||.||..| |.| ||...  .||.|..| | .
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 91274.m00102.AA TKL-Unique 172-262 30 1.9e-21 72.48 In-house 190-290 (290) Show / Hide 
Range on Protein: 172-262
Range on HMM: 190-290/290
Sequence Identity: 30% (31 aa)

PNWTPPEIYKG--KPRDEKSDVFLFGFLLFELLTGYI------PFQELSAEETQRVICV--SKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQL
..| .||. ..  . ..|||||. ||. | |..|. |      |.|... |.   .. .   ..|| ||.  |. .. ||. || .   .||.| ||.  
FRWMAPEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHR

F
 
L
Kinase 91274.m00102.AA Dicty4-Unclassified 172-262 38 2.7e-21 69.63 In-house 172-263 (263) Show / Hide 
Range on Protein: 172-262
Range on HMM: 172-263/263
Sequence Identity: 38% (36 aa)

PNWTPPEIYKGKPRDEKSDVFLFGFLLFELLTGYIPFQELS-AEETQRVICVSKKRPQIPSTAPEPLKLLIKHCW--SPKKINRPTFAEIYQLF
| |. ||. ..     ||||. .. .|.||.||  |.||     .  | .|  | ||.||.  .  .| ||| ||  .|.|  |||. .| |  
PKWESPECLMHESYNQKSDVYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNK--RPTMNQIIQYL
Kinase 91274.m00102.AA MLK 174-262 37 3.5e-18 56.47 In-house 192-280 (280) Show / Hide 
Range on Protein: 174-262
Range on HMM: 192-280/280
Sequence Identity: 37% (33 aa)

WTPPEIYKGKPRDEKSDVFLFGFLLFELLTGYIPFQELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQLF
| .||. |     . |||  .| || |||||  |...  .      . . |    |||| ||| . |.. || .    ||.|.|| | .
WMAPEVIKESTWSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAMNKLTLPIPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase 91274.m00102.AA HH498 174-262 28 7.2e-18 52.86 In-house 191-284 (284) Show / Hide 
Range on Protein: 174-262
Range on HMM: 191-284/284
Sequence Identity: 28% (27 aa)

WTPPEIYK-GKPRDEKSDVFLFGFLLFELLTGYIPFQELSAEETQRVICVSKKRPQIPST----APEPLKLLIKHCWSPKKINRPTFAEIYQLF
|  ||... .   ..| ||| ..  ..|..|. .||  .        .   . || || |     | .   ||  ||.|   |||.|..|  . 
WMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 91274.m00102.AA Dicty5 172-266 34 1.2e-17 57.27 In-house 167-260 (260) Show / Hide 
Range on Protein: 172-266
Range on HMM: 167-260/260
Sequence Identity: 34% (33 aa)

PNWTPPEIYKGKPRDEKSDVFLFGFLLFELLTGYIPFQELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQLFELGT
..|  .|...|.| ..| ||. ||  |.|..|   |. .. .   . |.  .  || || . |     ||| ||  |  |||.| || . ||   
QCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNI-NNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 91274.m00102.AA LRRK 186-264 30 7.2e-17 56.2 In-house 260-351 (351) Show / Hide 
Range on Protein: 186-264
Range on HMM: 260-351/351
Sequence Identity: 30% (28 aa)

DEKSDVFLFGFLLFELLTGY-IPFQELS-A-----EETQRVICVSKKRPQIPST-APE-----PLKLLIKHCWSPKKINRPTFAEIYQLFEL
.||.|.. || .|.||||.  .||.|..       .|... .  .. || ||..  |.      .. ||.|||. .  .||.| .| .  . 
TEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 91274.m00102.AA Pkinase_Tyr 187-262 35 1.1e-13 47.02 Pfam 193-270 (270) Show / Hide 
Range on Protein: 187-262
Range on HMM: 193-270/270
Sequence Identity: 35% (28 aa)

EKSDVFLFGFLLFELLT-GYIP-FQELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQLF
.||||  || |..|..| | .| ....| ||  . |  .  |  .|  .|...  |.|.|| ..  .||||.||.. .
TKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 91274.m00102.AA Pkinase 172-262 22 1.2e-11 42.21 Pfam 175-293 (293) Show / Hide 
Range on Protein: 172-262
Range on HMM: 175-293/293
Sequence Identity: 22% (27 aa)

PNWTPPEIYK-GKPRDEKSDVFLFGFLLFELLTGYIPFQEL---SAEETQRVICVSKKRPQIPSTAP-----------------------EPLKLLIKHC
|.. .||. . |.. . |.|.. .| .|.|.|.|. ||..        .|... . ...|....  |                       |..| .|| |
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

WSPKKINRPTFAEIYQL--F
. ..   |||...| |   |
LCKDPKKRPTAEQILQHPWF
TyrKc 91274.m00102.AA TyrKc 23-262 18 1.4e-11 -35.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-262
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)

FSFIQQICHGSF-DLWLAKSNSKEDSYFYAKQV----TRQTSKKDTAELFEQLSRIAEL--KHPFILSFIGVTQS--------PPFTGFTE-AVGRNLQE
 ...... .| |   .... .          ||     .  .    ... . ..   .|  .|| |. ..||  .        .|    .| . . .|..
ITLGKKLGEGAFGEVYKGTWK---------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

MLEDPACDSILTGTKTTIIAMCIADAMEFIHKKGYSMPHLNTGS----------IFITEDLTPRLS------LIEDG----------------CME--LP
 | ..  .  |.  .   ..  ||. ||..|.|                     . ..|..| . |       |.|.                .    ||
YLRKHRPK--LCMKDLLSFCWQIACGMEYLHSK----------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLP

-NWTPPEIYKGKPRDEKSDVFLFGFLLFELLT-GYIPFQE-----LSAEETQRVICVSKKRPQIPS-------TAPEPLKLLIKHCWSPKKINRPTFAEI
  |..||  . .   .||||. || ...|..| |  |  .     .|..|  . .   . .|| |.       ..|. .  ..| ||  .  .||||.||
IRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

YQLF
...|
HECF
Kinase 91274.m00102.AA LZK 229-262 52 3.8e-11 33.76 In-house 208-241 (241) Show / Hide 
Range on Protein: 229-262
Range on HMM: 208-241/241
Sequence Identity: 52% (18 aa)

IPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQLF
.|||.|| .|||.| ||| |  ||| |  | .  
MPSTCPEGFKLLMKQCWSQKPRNRPSFRQILMHW
S_TKc 91274.m00102.AA S_TKc 23-262 13 1.3e-08 -50.55 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-262
Range on HMM: 1-231/231
Sequence Identity: 13% (39 aa)

FSFIQQICHGSF-DLWLAKSNSKEDSYFYAKQVTRQTSKKDTAELFEQLSRIAELKHPFILSFIGVTQSPPFTGFTEAVGR---NLQEMLEDPAC---DS
. ....| .|.|   .... ..  . ..  |..           .   ..   . .||.|  ...| |.  .  ..| ..    .| .....  .   ..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

ILTGTKTTIIAMCIADAMEFIHKKGY-------------------------SMPHLNTGSIFITEDLTPRLSLIEDGCMELPNWTPPEIYKGKPRDE-KS
 ..   .  ..  |..|.|..|..|                           .                      . .   |.. .||.    . .  |.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL----------------------TTFCGTPWYMAPEVL---GYGKCKC

DVFLFGFLLFELLTGYIPFQELSAEETQRVICVSKKRPQIPSTAPEPLKLLIKHCWSPKKINRPTFAEIYQ---------LF
|.  .| .|.|.|.|| ||.    ... ..|.            ....| .|..|.     .|||  |. |          |
DWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91274.m00102.AA LZK 174-210 40 4.5e-07 19.8 In-house 153-189 (241) Show / Hide 
Range on Protein: 174-210
Range on HMM: 153-189/241
Sequence Identity: 40% (15 aa)

WTPPEIYKGKPRDEKSDVFLFGFLLFELLTGYIPFQE
|  ||. .  |  || |.. ||  | |.||. ||...
WMAPEVIRNEPCSEKVDIWSFGVVLWEMLTCEIPYKD
Kinase 91274.m00102.AA TKL 53-92 25 0.007521 6.11 In-house 59-98 (364) Show / Hide 
Range on Protein: 53-92
Range on HMM: 59-98/364
Sequence Identity: 25% (10 aa)

QVTRQTSKKDTAELFEQLSRIAELKHPFILSFIGVTQSPP
|   .....   .. |..  .  |.|| |..|.|. ..||
QLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPP
Kinase 91274.m00102.AA MLK 52-92 24 0.091534 2.06 In-house 33-82 (291) Show / Hide 
Range on Protein: 52-92
Range on HMM: 33-82/291
Sequence Identity: 24% (12 aa)

KQVT--------RQTSKKDTAELFEQLSRIAELK-HPFILSFIGVTQSPP
|.|.          ....|  . ...|...  .  || |  | || ..||
KRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP