Gene 82319.m00029 (T.vaginalis)

82319.m00029

Species: T.vaginalis
Alias: TvagK0804, 82319.m00029
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: STE20-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
82319.m00029.AA Protein None 336 None Fasta, JSON
82319.m00029.kin_dom Protein Kinase Domain None 149 None Fasta, JSON

Protein domain

Protein domains of 82319.m00029.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82319.m00029.AA YSK 28-176 40 6.2e-52 154.46 In-house 111-257 (257) Show / Hide 
Range on Protein: 28-176
Range on HMM: 111-257/257
Sequence Identity: 40% (60 aa)

ALLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPEMLTNN-TGYTEKTDIWGLGLVLIELATGKMPYAGMKFM
.| ||||.  ||||| . |.| ..||. || ||| |  . .. .||   |   |   .||||    . ..| .| ||| ||   .|.|.|  ||. .. |
GLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFV---GTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPPYCDYHPM

ESMASIITKEPPTLSKDKHSSLICDFVNLCLNTNPKKRASAEDLADHKFP
  |  |. ..||.|.. ..|    .||..||| .|..| ||..|  ||| 
RVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 82319.m00029.AA STE 28-176 30 2.3e-51 176.97 In-house 163-359 (359) Show / Hide 
Range on Protein: 28-176
Range on HMM: 163-359/359
Sequence Identity: 30% (63 aa)

A-LLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQ----------------NGQKR-SAAVSMYGDACYMAPEMLTN-----NTGYTEKTDIW
. | ||||.| ||||| ..|||.     .||.|||....|..                ..||| . . .      .||||....     . ||..| |||
GLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-----WMAPEVIQQNGQGRDKGYDTKCDIW

GLGLVLIELATGKMPYAGMKFMESMASIITK---------------EPPTLSKD------------------KHSSLICDFVNLCLNTNPKKRASAEDLA
 ||...||.|||| |.. |. |. |  |...               .||.|  .                  | |.  .||.|.||. .|.||..|..| 
SLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLL

D--HKFP
   |.| 
KSEHPFI
Kinase 82319.m00029.AA STE20 28-176 39 2.5e-51 176.85 In-house 129-288 (288) Show / Hide 
Range on Protein: 28-176
Range on HMM: 129-288/288
Sequence Identity: 39% (65 aa)

ALLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQ-----NGQKRSAAVSMYGDACYMAPEMLTNN----TGYTEKTDIWGLGLVLIELATGKM
.| |||||| ||||| ..||| . .|..||.|||.. .|..     ...||    .. |  ..||||..  .     ||..|.||| ||  .||.|.|. 
GLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKR---NTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEP

PYAGMKFMESMASII--TKEPPTLS---KDKHSSLICDFVNLCLNTNPKKRASAEDLADHKFP
||. |  |  |  |.  ...||||.   ..| |.  .|||..||. .|.||..|..|  |.| 
PYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 82319.m00029.AA MST 29-176 42 2.2e-46 145.37 In-house 110-254 (254) Show / Hide 
Range on Protein: 29-176
Range on HMM: 110-254/254
Sequence Identity: 42% (63 aa)

LLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPEMLTNNTGYTEKTDIWGLGLVLIELATGKMPYAGMKFMES
| |||.|. ||||| .|||| |  | .||.||| .  |.    ||   .   |  ..|||| .... .|. |.||| ||   ||.| |. ||.  . |  
LQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVI---GTPYWMAPEVIQEI-KYDCKADIWSLGITAIEMAEGMPPYSDIHPMRA

MASIITKEPPTLSK-DKHSSLICDFVNLCLNTNPKKRASAEDLADHKFP
|. |..| |||... .. |.   |||  ||  || .|..||.|  | | 
MFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 82319.m00029.AA PAKA 28-176 40 5.8e-38 130.79 In-house 115-260 (260) Show / Hide 
Range on Protein: 28-176
Range on HMM: 115-260/260
Sequence Identity: 40% (61 aa)

ALLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPEMLTNNTGYTEKTDIWGLGLVLIELATGKMPYAGMKFME
.| ..||.| ||||| | ||| .. |. |. ||| .. | |  |||    .| |   .|||| .. .  | || ||| ||  .||.. |  ||  ..   
GLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKR---NTMVGTPYWMAPEVIRRK-QYDEKVDIWSLGIMAIEMIEGEPPYLNEPPLR

SMASIITK-EPPTLSKDKHSSLICDFVNLCLNTNPKKRASAEDLADHKFP
 |  | |.  |. ...|| |. .|||...||. ....||||..|  | | 
AMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 82319.m00029.AA STE7 28-176 34 3.5e-37 129.83 In-house 122-288 (288) Show / Hide 
Range on Protein: 28-176
Range on HMM: 122-288/288
Sequence Identity: 34% (60 aa)

ALLYLHS-NHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSA--AVSMYGDACYMAPEMLT-NNTGYTEKTDIWGLGLVL-IELATGKMPY--
.| |||.  . ||||.  .||| | .|| ||.||| .  |.      |   |... | . ||||| .. |...|. ..|.| ||. . ||.|||. ||  
GLHYLHEKHKIIHRDVKPSNILVNSRGQVKLCDFGICGQLVD-----SMDAATTFVGCQPYMAPERIDGNKQHYDVRSDVWSLGITMGIEMATGRYPYPN

-----------------AGMKFMESMASIITK-EPPTLSKDKHSSLICDFVNLCLNTNPKKRASAEDLAD-HKFP
                 . | ..| .  |..  .||.|   | |   .||||.||  .|..|.. ..|   | | 
WNTHPPDQKQYNNMFQPE-MAIFEQLTCIVNENPPPRLP--KFSPEFQDFVNKCLQKDPNERPKYHQLMKEHPFI
Kinase 82319.m00029.AA TAO 28-176 41 5.5e-37 118.15 In-house 111-254 (254) Show / Hide 
Range on Protein: 28-176
Range on HMM: 111-254/254
Sequence Identity: 41% (63 aa)

ALLYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPE-MLTNNTG-YTEKTDIWGLGLVLIELATGKMPYAGMKF
.| |||| . |||||. ||||   ||| ||.||| | |...       | |  |   .|||| .|    | |..| |.| ||.  ||||  | |.  |  
GLRYLHSHKMIHRDIKAGNILLTEHGQVKLADFGSA-SMVC------PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNA

MESMASIITKEPPTLSKDKHSSLICDFVNLCLNTNPKKRASAEDLADHKFP
|  .  |   ..|||.... |   ..||. ||.  |..| |||..  |.| 
MSALYHIAQNDSPTLQQNEWSDCFHQFVDKCLQKMPQERPSAEECLRHEFV
Kinase 82319.m00029.AA STE7-Unclassified 28-176 32 2.8e-35 121.74 In-house 131-301 (301) Show / Hide 
Range on Protein: 28-176
Range on HMM: 131-301/301
Sequence Identity: 32% (58 aa)

ALLYLHSNH-EIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSA--AVSMYGDACYMAPEMLTNN----TGYTEKTDIWGLGLVLIELATGKMPY
.| |||  |  |||||  |||| |. ||.|..||| .  |.      .   |... |   ||.|| .  .     .|..|.||| |||...|.|||| ||
GLWYLHEKHHIIHRDIKPGNILVNSKGQVKICDFGVCGQLEN-----TLDEAKTWVGCQMYMSPERIQGQMPHRPSYSVKSDIWSLGLTIWECATGKYPY

---------------AGMKFMESMASIITKEPPTLSKDK----HSSLICDFVNLCLNTNPKKRASAEDLAD-HKFP
                .| | |  ..|.... |.| .|.     |.   ||.. |.  .|. |... .|   | . 
EYNFQSEQYNQNFQPENMSFWELLSCIVNFPVPRLPDDPEDIIWSKEFMDFISKCCKKHPRERPDIHQLLNEHPWI
Kinase 82319.m00029.AA STE11 31-176 33 1.9e-32 114.1 In-house 131-303 (303) Show / Hide 
Range on Protein: 31-176
Range on HMM: 131-303/303
Sequence Identity: 33% (58 aa)

YLHSNHEIHRDIRSGNILFNAHGQ-AKLSDFGLATSLIQNGQKRSA-------AVSMYGDAC--------YMAPEMLTNNT--GYTEKTDIWGLGLVLIE
||||.. |||||   ||| .. |.  ||.||| |..| ..... .         .||.|           .||||.... .  ||. | ||| || . ||
YLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPEVIKQEGRDGYGRKADIWSLGCTVIE

LATGKMPYAGMKF--MESMASIITKEPPTLS-KDKHS------SLICDFVNLCLNTNPKKRASAEDLADHKFP
 |||| |......  |  |. |.... |.    .. |          ||...|.  .||||..| .| .|.| 
MATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 82319.m00029.AA TKL 28-174 20 3.9e-32 113.01 In-house 144-364 (364) Show / Hide 
Range on Protein: 28-174
Range on HMM: 144-364/364
Sequence Identity: 20% (45 aa)

ALLYLHSNH--------EIHRDIRSGNILFNAHGQ--------------AKLSDFGLATSLIQNGQKRSAAVS----------------MYGDACYMAPE
.. ||||..         ||||. | ||| . ...              .|..||||.... |.|..   . .                  |  ..||||
GMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPE

MLTNNT---------------GYTEKTDIWGLGLVLIELATGKMPYAGMKFM--------ESMASIIT--KEPPTLS-----------KDKHSSLICDFV
.| ...                |.||.|..  |.|| |..|.. ||.....|        | |....   ...|..             .     ...  
VLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLM

NLCLNTNPKKRASAEDLADHK
  | ...|.|| |.... .. 
QDCWDHDPEKRPSFQEILKRL
Kinase 82319.m00029.AA Pkinase 28-176 29 1.8e-29 105.31 Pfam 120-293 (293) Show / Hide 
Range on Protein: 28-176
Range on HMM: 120-293/293
Sequence Identity: 29% (52 aa)

ALLYLHSNHEIHRDIRSGNILFNAHGQA----KLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPEMLTNNTGYTEKTDIWGLGLVLIELATGKMPYAGM
.| |.||.  ||||. . |||.. .|.     |..|||||  .     . | . .  |   ||||| .  ...|. | |.|..|..|.|...|. |. | 
GLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGH

----KFMESMASIITKEPPTLSKD---KHS-------------------SLICDFVNLCLNTNPKKRASAEDLADHKFP
    . .. |. |  . .| |. |   ..|                   .  .||.. ||. .|||| .||..  |.. 
CWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82319.m00029.AA Pkinase_Tyr 31-124 32 8.2e-15 50.79 Pfam 126-220 (270) Show / Hide 
Range on Protein: 31-124
Range on HMM: 126-220/270
Sequence Identity: 32% (32 aa)

YLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKR-SAAVSMYGDACYMAPEMLTNNTGYTEKTDIWGLGLVLIELAT-GKMP-YAGMK
||.|.. ||||..  |.| .  ...| .|||||  . .|      .. .       |||| . ..  .|.|.|.|  | .. |. | |..| |.||.
YLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPTYPGMS
S_TKc 82319.m00029.AA S_TKc 1-176 21 1.3e-12 7.86 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-176
Range on HMM: 18-231/231
Sequence Identity: 21% (52 aa)

MTSSSSDMAVALR--------------------------------------MSH---SLLPLLLI--------------------LSMALLYLHSNHEIH
 .  ...  ||.                                       ...   .|. ..                      .  || |.||.. ||
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIH

RDIRSGNILFNAHGQAKLSDFGLATSLIQNGQKRSAAVSMYGDACYMAPEMLTNNTGYTE-KTDIWGLGLVLIELATGKMPYAGMKFMESMASIITKEPP
||.   |||..   . |..|||||. |           .. |   |||||.|    ||.  | |.| .| .|.|...|. |.     |. |  .|     
RDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG----

TLSKDKHSSLICDFVNLCLNTNPKKRASAEDLAD-------HKFP
       |.  .||.. ||. .|.|| .| ..         | . 
-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 82319.m00029.AA TyrKc 2-175 16 9.3e-07 -113.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-175
Range on HMM: 1-280/280
Sequence Identity: 16% (47 aa)

TSSSSD-------------------------------------MAVA------------------------------------------LRMSHSLLPLL
 .                                         |                                             || ..  |.. 
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

LILSMAL------LYLHSNHEIHRDIRSGNILFNAHGQAKLSDFGLATSLIQN---GQKRSAAVSMYG-----DAC------YMAPEMLTNNTG-YTEKT
  ||...       ||||.. ||||.   |.| .. ...| |||||.  .      |    .. ..|      ..        |||| .  |.| .|.|.
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG----ESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFTTKS

DIWGLGLVLIELAT-GKMPYAG-----MKFMESMASIITKEPPTLSKD--------KHSSLICDFVNLCLNTNPKKRASAEDLADHKF
|.|  | .. |. | |..|| |     |.  | .. . . . .   ..         .. .       | . .|..| . ...  ..|
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI-HECF