Gene 81246.m00128 (T.vaginalis)

81246.m00128

Species: T.vaginalis
Alias: TvagK0142, 81246.m00128
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81246.m00128.AA Protein None 222 None Fasta, JSON
81246.m00128.kin_dom Protein Kinase Domain None 162 None Fasta, JSON

Protein domain

Protein domains of 81246.m00128.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81246.m00128.AA Pkinase 7-164 28 1.9e-46 165.28 Pfam 105-293 (293) Show / Hide 
Range on Protein: 7-164
Range on HMM: 105-293/293
Sequence Identity: 28% (55 aa)

FTDEELYKYSYEVLYAIKACHERNIAHSDIKPANFLIDHYGRL----KISDFGLSTL--YENKQLCHVFKGTRMFMAPEIFSADQYNPLVADVWSIGVTL
|...|. .| |..| ... ||...| | |.||.|.|||. | .    ||.||||. .  | |.. ...| ||. .||||.   .|| .  .|.||.|..|
FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCIL

YYMATRTFPFYSN------DQLSLQRMIEAGIYAEDEIHN---------------------LLFRKVVSRCLEVNVHKRATIAELLEMPYF
|.|... .||..       ||. . ..|  ... .|.                          .......||... .|| |....|. |.|
YEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81246.m00128.AA CAMK 19-164 21 4.4e-44 139.48 In-house 188-425 (425) Show / Hide 
Range on Protein: 19-164
Range on HMM: 188-425/425
Sequence Identity: 21% (50 aa)

VLYAIKACHERNIAHSDIKPANFLIDHY-----------------GRLKISDFGLSTLYEN------------------------KQLCHVFKGTRMFMA
.. |.. ||..||.| |.|| | |.|.                  . .||.|||... ..                          |... | ||  .||
ICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMA

-PEIFSA-------------DQYNPLVADVWSIGVTLYYMATRTFPFYSN-------------DQLSLQRMIEAGIYA-EDE----------------IH
 ||...               .| .  .|.||.|| || | . ..|||.              ..  | ..| .| |  ...                | 
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDIS

NL-------LFRKVVSRCLEVNVHKRATIAELLEMPYF
.          .  ....|.|.  ||.||.. |. | .
DEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81246.m00128.AA CAMKL 26-164 30 1.8e-40 126.75 In-house 143-297 (297) Show / Hide 
Range on Protein: 26-164
Range on HMM: 143-297/297
Sequence Identity: 30% (50 aa)

CHERNIAHSDIKPANFLIDHYG--RLKISDFGLSTLYEN-----KQLCHVFKGTRMFMAPEIFSA--DQYNPLVADVWSIGVTLYYMATRTFPFY-----
||...|.| |||| | |.|. |   .||.|||.|..|..      |... | |.  .||||||.   ..|.   .|.||.||.|| | . ..||      
CHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYN

-----SNDQLSLQRMIEAGIYA-----EDEIHNLLFRKVVSRCLEVNVHKRATIAELLEMPYF
      .  | .. |.  . .        . ..|.     .. |.||  ||.|| .... | .
KQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLI-----RKMLQVNPEKRPTIHQIMNHPWM
Kinase 81246.m00128.AA Ciliate-E2 3-164 20 2.4e-35 118.8 In-house 134-365 (365) Show / Hide 
Range on Protein: 3-164
Range on HMM: 134-365/365
Sequence Identity: 20% (51 aa)

EKPE----FTDEELYKYSYEVLY---------------AIKACHERN-IAHSDIKPANFLIDHYGRLKISDFGLSTLYENK-------------------
...|    ||..|  ......|.               |.. .|..| | | |||| | |.     .||.|||||. | ..                   
HEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDT

-------------QLCHVFKGTRMFMAPEIFSADQY--------NPLVADVWSIGVTLYYMATRTFPFYSNDQLSLQRMIEAGIYAED------------
             .. . . || ..|||||..  .|            .|.||.||.||.| .  .||        |. |. . .  .            
SRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQ

------EIHNLLFRKVVSR----CLEVNVHKRAT-IAELLEMPYF
      . . .      ..    .|...  || | . ..|. |.|
CKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81246.m00128.AA MARK 19-164 38 5.3e-35 111.98 In-house 113-262 (262) Show / Hide 
Range on Protein: 19-164
Range on HMM: 113-262/262
Sequence Identity: 38% (60 aa)

VLYAIKACHERNIAHSDIKPANFLIDHYG--RLKISDFGLSTLYENKQLCHVFKGTRMFMAPEIFSADQYNPLVADVWSIGVTLYYMATRTFPFY--SND
...|.. ||..||.| |||| | |||. |    ||.|||.|.  .. |.   | ||  .||||||.   |.   .|.|| || ||.| . .|||   ..|
IVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQD

QLSLQRMIEAGIYA-----EDEIHNLLFRKVVSRCLEVNVHKRATIAELLEMPYF
.  |.. | .| |       .|..||.     .| | || ..|.|| |... | .
YKELYKKILRGKYDIPCHVSKECRNLI-----QRLLTVNPEERPTIEEIMKHPWM
Kinase 81246.m00128.AA Ciliate-E2-Unclassified 6-164 25 7e-34 114.91 In-house 134-352 (352) Show / Hide 
Range on Protein: 6-164
Range on HMM: 134-352/352
Sequence Identity: 25% (55 aa)

EFTDEELY-----KYSYEVLYAIKACHERN-IAHSDIKPANFLIDHYG---RLKISDFGLSTLYEN----------------KQLCHVFKGTRMFM----
.||...       .| ...| ... .|. | | | |||| | |.|  |   ..||.|||.|  |..                .|... | || ..|    
IFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYT

APEIFSADQYNPLVA---DVWSIGVTLYYMATRTFPFYSNDQLS----------------LQRMIEAGIYAEDE--------IHNLLFRKVVS----RCL
|||..   .|.   |   |.|| || ||.| . ..|||.|.. .                |.. | ....  ..        . .      ..    ..|
APEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKML

EVNVHKRATIAELLEMPYF
..|  || |. ..|. |.|
KKNPNKRITFEQILNHPWF
Kinase 81246.m00128.AA ULK 27-164 25 1.9e-30 105.28 In-house 143-324 (324) Show / Hide 
Range on Protein: 27-164
Range on HMM: 143-324/324
Sequence Identity: 25% (47 aa)

HERNIAHSDIKPANFLIDHY------------GRLKISDFGLSTLYEN----KQLCHVFK------GTRMFMAPEIFSAD----QYNPLVADVWSIGVTL
|..|| | ||||.| || .             |.|||.|||..   .|    .|.|. ..      || ..|||.|..      .|.   .|.||.|. .
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

YYMATRTFPFYSNDQLSLQ----RMIEAG------IYA---------EDEIHNLLFRKVVSRCLEVNVHKRATIAELLEMPYF
|.| .   ||.|.   ...    ..|. |      |.          .| .    ..   .|.|...  .| .. |....| |
YEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 81246.m00128.AA CAMKK-Unclassified 14-164 25 2e-29 92.79 In-house 182-392 (392) Show / Hide 
Range on Protein: 14-164
Range on HMM: 182-392/392
Sequence Identity: 25% (55 aa)

KYSYEVLYAIKACHERN---------------------IAHSDIKPANFLIDHYGR-----LKISDFGLSTLYE-NKQL-CHVFKGTRMFMAPEIFSAD-
||. ... ... .| .|                     | | |||| | |||| ..     .||.|||.|.. |  .|       ||  ||||| .|   
KYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEFWSKEN

-QYNPLV-------------------------ADVWSIGVTLYYMATRTFPFYSNDQLSLQR-MIEAGI--YA---EDEIHNLLFRKVVSRCLEVNVHKR
  |...                          ||.|| |||.|.|.. . ||....   |   ||....       .... . .|     .... |  ||
FKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHC-SHEFKDLIQKMCDKNPKKR

ATIAELLEMPYF
.||  .|. |.|
ITIDQMLVHPWF
Kinase 81246.m00128.AA CAMKK 14-164 25 3.8e-29 89.3 In-house 180-396 (396) Show / Hide 
Range on Protein: 14-164
Range on HMM: 180-396/396
Sequence Identity: 25% (55 aa)

KYSYEVLYAIKACH-ERN-------------------IAHSDIKPANFLIDHYG---RLKISDFGLSTLYE-NKQLCHV-----------FKGTRMFMAP
||  ... ... .| ...                   | | |||| | |||. |   ..||.||| |.  | ..|.                ||  ||||
KYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAP

EIFSA-DQ--------------YNPLVADVWSIGVTLYYMATRTFPFYSNDQLSLQR---MI--EAGIYAE-----------DEIHNLLFRKVVSRCLEV
| .|  .|              |.   ||.|. |||||.. . . ||..|. . | .   .|  .   . |           ..  . ..  .  |.|| 
ELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKDLIKRMLEK

NVHKRATIAELLEMPYF
|. || ||..... | .
NPTKRITIPQIKVHPWV
Kinase 81246.m00128.AA ULK 27-164 24 8.2e-29 97.75 In-house 147-329 (329) Show / Hide 
Range on Protein: 27-164
Range on HMM: 147-329/329
Sequence Identity: 24% (46 aa)

HERNIAHSDIKPANFLIDHY------------GRLKISDFGLSTLYENK------QLCHV----FKGTRMFMAPEIFSAD----QYNPLVADVWSIGVTL
|..|| | ||||.| ||.              |.|||.|||..   .|        .  |    ..|| ..|||.|..      .|.   .|.||.|. .
HKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIF

YYMATRTFPFYSNDQLSLQ-----RMIE--------------------AGIYAEDEIHNLLFRKVVSRCLEVNVHKRATIAELLEMPYF
|.| .   |||..   ...     . |.                    ...   .|...|.     .|.|...  .| .. ||...| |
YEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLI-----RRMLQYDEKDRISWEELFNHPWF
Kinase 81246.m00128.AA STE 14-164 20 5.4e-26 88.83 In-house 155-359 (359) Show / Hide 
Range on Protein: 14-164
Range on HMM: 155-359/359
Sequence Identity: 20% (43 aa)

KYSYEVLYA-IKACHERNIAHSDIKPANFLIDHYGRLKISDFGLSTLYEN-----------------KQLCHVFKGTRMFMAPEIFSADQYNPL------
.. ...| .  .  |. .| | |||||| |.      |..|||...  ..                 .| .  | ||  .||||. . .. .        
YICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQG-RDKGYDT

VADVWSIGVTLYYMATRTFPFYSNDQLSLQRMIEAGIYAED-------------EIHN----------------------LLFRKVVSRCLEVNVHKRAT
 .|.||.| |.  |||   |.     ..   ||  ......              . .                        |.  ...||. . .||.|
KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT

IAELLE--MPYF
  .||.   | .
ASQLLKSEHPFI
S_TKc 81246.m00128.AA S_TKc 1-164 21 2.1e-15 49.1 SMART 18-231 (231) Show / Hide 
Range on Protein: 1-164
Range on HMM: 18-231/231
Sequence Identity: 21% (50 aa)

MIEKP--------------------------------------------EFTDE---ELYK--------------------YSYEVLYAIKACHERNIAH
 ..|                                             |. |    .|..                    | |... |.. ||...| |
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIH

SDIKPANFLIDHYGRLKISDFGLSTLYENKQLCHVFKGTRMFMAPEIFSADQYNPLVADVWSIGVTLYYMATRTFPFYSNDQLSLQRMIEAGIYAEDEIH
 |.||.| |.|.  ..||.||||....      . | ||. .||||..   .|..  .|.||.|..|| |...  ||. ..|. ....            
RDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------

NLLFRKVVSRCLEVNVHKRATIAELLE-------MPYF
   ..  ...||...  || |. |.|.       .|.|
SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
TyrKc 81246.m00128.AA TyrKc 2-162 13 0.00011 -146.89 SMART 1-280 (280) Show / Hide 
Range on Protein: 2-162
Range on HMM: 1-280/280
Sequence Identity: 13% (37 aa)

IE-------------------------------------------------------------------------------------------KPEFTDE
|.                                                                                           .|... .
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPKLCMK

ELYKYSYEVLYAIKACHERNIAHSDIKPANFLIDHYGRLKISDFGLSTLYENK-------QLCHV--FKGTRM-----FMAPEIFSADQYNPLVADVWSI
.| .... .       |..|. | |.   | |... .. ||||||||   ...       .  ..   ||...      |||| .    ...   |||| 
DLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS-DVWSF

GVTLYYMATRTFPFYSN------DQLSLQRMIEAG--IYAEDE--------IHNLLFRKVVSRCLEVNVHKRATIAELLEMP
||... . |.  . |..      .   . . ...|      ..         .  ... . ..| . . ..| | .|. |  
GVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF