Gene 90149.m00309 (T.vaginalis)

90149.m00309

Species: T.vaginalis
Alias: 90149.m00309, TvagK0406
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
90149.m00309.AA Protein None 436 None Fasta, JSON
90149.m00309.kin_dom Protein Kinase Domain None 253 None Fasta, JSON

Protein domain

Protein domains of 90149.m00309.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 90149.m00309.AA PH 15-109 27 9.2e-15 55.88 Pfam 1-92 (92) Show / Hide 
Range on Protein: 15-109
Range on HMM: 1-92/92
Sequence Identity: 27% (27 aa)

MELKGWLKKKSLGEKKWVKRYLVLRENNLTLYFDETCKDADTTYQLSSNTTVEQIVDNNTPKFMLTIEGQD--PITFSTDTSENVQKWITGIRSSFE
 ...|||.||. . |.| ||..||..|.| .| |.. ..   .. ||.  .|. ..||   .... |   |   ..|.....|  . |.. |.|   
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDN-KRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 90149.m00309.AA PH 15-111 24 1e-13 52.79 SMART 1-82 (82) Show / Hide 
Range on Protein: 15-111
Range on HMM: 1-82/82
Sequence Identity: 24% (24 aa)

MELKGWLKKKSLGEKKWVKRYLVLRENNLTLYFDETCKDADTTYQLSSNTTVEQIVDNNTPKFMLTIEGQDPITFSTDTSENVQKWITGIRSSFESS
....|||.|||    .| ||..||... |..| |.   .   .. ||.  ||.  .      | ..  ..  ..|.....|  |.|.. |..  ...
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 90149.m00309.AA AGC 119-371 32 7.2e-161 419.65 In-house 1-395 (395) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-395/395
Sequence Identity: 32% (128 aa)

FDILHVLGRGAFGKVMLVRHR------SSMKLYAIKSIQKRK---LLDA-MKSHT-----------VIAERNILMKAH----------HPFIVQ-LFFAF
|..| |.|.|.||||.|||..      ...|.||.| ..|..   ...  |  ||           | .|||||.|..          |||||. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNPSK--FYLGLEYVP---------GG-ELFYHLT---KRGTFPINEVRLYSAE-------IALALSYLHS-IGIIYRD-LKPENVMLDSTGHIKLTDFG
|....   |. .||.|         || |||.||    |.|.|. ...| | ||       |.||| ||||  |||.|| |||||..||. |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTEVFELEECG--------------------------------------------------DSFCG--TSRYLSPEMIYKIKYTHKIDWWS--LGILMY
|..|.   .| |                                                   .|||  |  |..||..    |..  ||||  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMIVGHPPFDSQN----------RSQLYNDIT------HSDPVFP----------SSFPVDAKDLVCKLLTKNPNQRPD----------FSGIKDHVFF
||..|.||| ..|          . .... |       . .. ||          ..| ..||||. |||.|.|..|.           .. ||.| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 90149.m00309.AA SGK 119-371 42 1.1e-125 390.26 In-house 1-283 (283) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-283/283
Sequence Identity: 42% (120 aa)

FDILHVLGRGAFGKVMLVRHRSS------------------MKLYAIKSIQKRKLL-------DAMKSHTVIAER-NILMKAHHPFIVQLFFAFQNPSKF
||.|.|.| | ||||..|.| .                    |.||.| .||   .          .   . ||| .|| .  |||||.| .|||.. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGELFYHLTKRGTFPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEECGDSFCGTSRYLSPEMIYKI
|. ..|| |||.|||| ... ||  ..| | |||..|| ||||. ||||||||||..||. ||..||||||. |  . ..   .||||  || ||.. | 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

KYTHKIDWWSLGILMYEMIVGHPPFDSQNRSQLYNDITHSDPVFPSSFPVDAKDLVCKLLTKNPNQR----PDFSGIKDHVFF
 .    |||.||...|||..| ||| |.|..|.|  | ...  .| .. .||.||   ||.|.| .|     ||  ||.|.||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 90149.m00309.AA Akt 119-371 43 3.4e-123 395.7 In-house 1-264 (264) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-264/264
Sequence Identity: 43% (114 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLY-AIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPIN
||.|.|||.|.||||.||.  .. |.| |.|...|.....  .   ...||||| .  |||||.| ..||.. | |. ..|..|||||||| ....|. .
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EVRLYSAEIALALSYLHSIGIIYRD-LKPENVMLDSTGHIKLTDFGLSTEV-FELEECGDSFCGTSRYLSPEMIYKIKYTHKIDWWS-LGILMYEMIVGH
. | | ||| ||. .||| .||||| |||||...|..|||.||||||. |      .  ..||||  ||.||.. .. .| . |||. ||..||||. | 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFDSQNRSQLYNDITHSDPVFP--SSFPVDAKDLVCKLLTKNPNQRP-----DFSGIKDHVFF
||| .|.. |..  |  ..  ||  . .  ..|||. .||.|.|..|.     |   ||.| .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 90149.m00309.AA AktR 119-371 45 2.1e-110 373.1 In-house 1-268 (268) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-268/268
Sequence Identity: 45% (121 aa)

FDILHVLGRGAFGKVMLVRHR-SSMKLYAIKSIQKRKLLDAMKSHTVIAERNILM-KAHHPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPI
|... .||.||||||.||...  . |.||.|.| | |. .  . | .| ||||.  .. |||||.|...||. .| .. .||.||||||.|| |...|  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

NEVRLYSAEIALALSYLHSI-GIIYRDLKPENVMLDSTGHIKLTDFGLST-EVFE-LEECGDSFCGTSRYLSPEMIYK-IKYTHKIDWWSLGILMYEMIV
...| |.|.| ||| |||.   |||||||||| .||. ||.|.||||||  .. .  .|  .|||||  |..|||| |   ..  .|||..||. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GHPPFDSQNRSQLYNDITHSD---PVFPSSFPVDAKDLVC-KLLTKNPNQRP-----DFSGIKDHVFF
|.|||...|. |..  |  ..   . .|| |   .|||.. ||| ||||.|.     ... ||.| .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 90149.m00309.AA S_TKc 119-371 36 4.6e-107 362.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-231/231
Sequence Identity: 36% (99 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPG--GELFYHLTKRGT---
..|| ..|.||||||...||... ...||| |            ... |..||.| |||.||.|. .||. ...|. .||..|  |.|| .. |||.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEECGDSFCGTSRYLSPEMIYKIKYTH-KIDWWSLGILMYE
   ||  ..| | ..|..|| |.|| |||.|||||||..||.  |||..||||....       ..||||  |..||..   .|.. |.||||.|...||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MIVGHPPFDSQNRSQLYNDITHSDPVFPSSFPVDAKDLVCKLLTKNPNQRPDFSGIKD-------HVFF
|..| |||.  .  .... |           . .|||...|.|.|.|..||    .         | .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90149.m00309.AA RSK 122-371 39 4.90000000001e-104 351.94 In-house 1-278 (278) Show / Hide 
Range on Protein: 122-371
Range on HMM: 1-278/278
Sequence Identity: 39% (111 aa)

LHVLGRGAFGKVMLVRHR---SSMKLYAIKSIQKRKLLDAMK-SHTVIAERNILMKAH-HPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGT---
| |||.|..||| |.|      . ..|| | ..|.|.  . |   .. .|||||.    |||||.|. ||| ..|.|| .||..|||||.|| |...   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDS---TGHIKLTDFGLSTE-VFELEECGDSFCGTSRYLSPEMIY---KIK-YTHKIDWWSLGI
|  .|.. | |||.||...||. |||.|||||||...|.    |||||||||.. . . . ..  ..||.|  |. |||.    . . ...  ||||||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYEMIVGHPPFDS---QNRSQLYNDITHSD--PVFP--SSFPVDAKDLVCKLLTKNPNQRPD-----FSGIKDHVFF
||||| .|.||| .   .||... . | . .  . .|  ..   .||||. |.|...|..|.       . ||.| .|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 90149.m00309.AA p70 119-371 38 1.2e-99 337.33 In-house 1-299 (299) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-299/299
Sequence Identity: 38% (115 aa)

FDILHVLGRGAFGKVMLVRHRS---SMKLYAIKSIQKRKLLDAMK--SHTV------------------------IAERNILMKAHHPFIVQLFFAFQNP
|  | |||.|..|||..||      . |.|| | ..|.| .   |   ||                          ||||||    ||||. |..|||  
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SKFYLGLEYVPGGELFYHLTKRGTFPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEEC----------GDSFCG
.| || ||| .|||||.|| . |... . .. | .|| .|| .||. |||||||||||.||.. ||..||||||. |  .  .             .|||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TSRYLSPEMIYKIKYTHKIDWWSLGILMYEMIVGHPPFDSQNRSQLYNDITHSD--PVFPSSFPVDAKDLVCKLLTKNPNQRPD-----FSGIKDHVFF
|  |  ||.. .  . | .||||||.||| | .| |||   || .  . |      .  |     ...||. ||| ..| ||          |. | ||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 90149.m00309.AA PKC 119-371 37 5.3e-96 311.67 In-house 1-262 (262) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-262/262
Sequence Identity: 37% (99 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKAH-HPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPIN
|. | |||.| ||||||.... . ..|||| . |   ..      . .|. .|  |  ||| ..|.  || ... .  .||| || | .|  . . |.  
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEECGDSFCGTSRYLSPEMIYKIKYTHKIDWWSLGILMYEMIVGHPPF
  | |.|||..|| .||. |||||||| .||.||. ||||..|||.. |    ..  ..||||  |..|| .   .|.. .|||..|.||||| .|..||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

DSQNRSQLYNDITHSDPVFPSSFPVDAKDLVCKLLTKNPNQR----PD----FSGIKDHVFF
. ..  .| . |.| .|..| .. ..|...  ...||||..|    |.    .  |..| ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 90149.m00309.AA RSK-Unclassified 119-371 38 2.1e-94 296.95 In-house 1-283 (283) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-283/283
Sequence Identity: 38% (109 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLT--KRGTFPI
|     .|.| |||| ||| . . ..||.|  .| |..   |   |. |.||.    |||||.|...||   . || .|| .||..| ||   |   |  
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

NEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEV---------------------FELEECGDSFCGTSRYLSPEMIYKIKYT
..|| | .|. .|| |||  ..|||||||.|..|.  ||..||||.|| .                       .      |||||  || ||||     |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

HKIDWWSLGILMYEMIVGHPPFDSQNRSQLYNDITHSDPVFP--SSFPVDAKDLVCKLLTKNPNQRP-----DFSGIKDHVFF
  .||| |||.|||| .| ||.   |.  ... |   .  ||  |    ...||. |||..||  |      |   || | ||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 90149.m00309.AA PKA 119-371 42 6.9e-92 311.58 In-house 1-263 (263) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-263/263
Sequence Identity: 42% (113 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIV-QLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPIN
|.|. .||.| ||.|||.||..| . ||.| . |..  .    . |. |.|||.  .||||| .. . ||.... |. .|||||||.|..| |.| |.  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EVRLYSA-EIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFELEECGDSFCGTSRYLSPEMIYKI-KYTHKIDWWSLGILMYEMIVGHP
. ..| | .| ||| ||||  |||||||||| ..|. ||||.|||| . .| .      . |||  || ||.|     .   .|||.|||| ||| .|.|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFDSQ--NRSQLYNDITHSDPVFPSSFPVDA---KDLVCKLLTKNPNQRP---DF--SGIKDHVFF
||     .  |.|. |   .  ||..| .||   |||. |||......|    ..    ||.| .|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 90149.m00309.AA Pkinase 119-371 30 7.7e-86 296.29 Pfam 1-293 (293) Show / Hide 
Range on Protein: 119-371
Range on HMM: 1-293/293
Sequence Identity: 30% (90 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVI-AERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPGG----ELFYHLT--KR
. |. ..|.|.||.| . .|... |..|.| | ||.  . .. . .  .|  |. . .||.||.|. .|..... |. .||..||    .|| ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTF--PINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHI----KLTDFGLSTEV-FELEECGDSFCGTSRYLSPEMIY-KIKYTHKIDWWSL
|.|  . .|.. |  .|. .| |.|| |||.|||||||...|..|||    |..||||.  .     .  ..||||..|..|| |    .|..|.|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILMYEMIVGHPPFDSQ------NRSQLYNDITHSDPVFPSSFP---------------------VDAKDLVCKLLTKNPNQRPDFSGIKDHVFF
|...|||. |.|||...      .  |... | . .. |... .                      ..||.....|.|.|..|| .  |. | .|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 90149.m00309.AA MAST 119-264 42 3.8e-65 208.84 In-house 1-146 (334) Show / Hide 
Range on Protein: 119-264
Range on HMM: 1-146/334
Sequence Identity: 42% (62 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKAHHPFIVQLFFAFQNPSKFYLGLEYVPGGELFYHLTKRGTFPINE
|..  ....||.||| ||.|... ...|.| | |. ... .  ..|..|||||  .  ||.| .| .||  .. .. .||. || .. .|   |.|. . 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

VRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLS
...| ||..|.| |||| ||. |||||.|. .||.|||||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLS
Kinase 90149.m00309.AA MAST 278-371 31 3e-30 94.47 In-house 225-334 (334) Show / Hide 
Range on Protein: 278-371
Range on HMM: 225-334/334
Sequence Identity: 31% (35 aa)

CGTSRYLSPEMIYKIK-YTHKIDWWSLGILMYEMIVGHPPFDSQNRSQLYNDITHSD---PVFPSS--------FPVDAKDLVCKLLTKNPNQRPDFS--
||| .|..|| | .   .   .||||.|| ||| .|| |||.  ..  ... |.. .     .|          ....|.||. |||. .|..|. ..  
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--GIKDHVFF
   .| | ||
ADEVKQHPFF
Kinase 90149.m00309.AA TyrKc 119-369 22 1.6e-16 44.38 SMART 1-280 (280) Show / Hide 
Range on Protein: 119-369
Range on HMM: 1-280/280
Sequence Identity: 22% (66 aa)

FDILHVLGRGAFGKVMLVRHRSSMKLYAIKSIQKRKLLDAMKSHTVIAERNILMKA--HHPFIVQLFFAFQNP-------SKFYLGLEYVPGGELFYHL-
   ...||.||||.|.. . .      |.|.... .          . | .|..|   ||| ||.|. .   .          .. .||.|.| |  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

TKRGTFPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLSTEVFEL-------EECGDSF--CGTS----RYLSPEMIYKIKYT
 .|....  .   ..  ||   .|||| ..| |||   |..... ...| .||||| .. .        .    .   .| .    | ..|| | . |.|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

HKIDWWSLGILMYEMI-VGHPPFDS-----QNRSQLYNDITHS-DPVFPSS--------FPVDAKDLVCKLLTKNPNQRPDFSGIKDHV
.| | || |..|.|.   | .|         . ....... .   .  | .         | .  ..  .    .|..|| || |..  
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 90149.m00309.AA Pkinase_Tyr 119-264 26 3.6e-12 41.85 Pfam 1-158 (270) Show / Hide 
Range on Protein: 119-264
Range on HMM: 1-158/270
Sequence Identity: 26% (44 aa)

FDILHVLGRGAFGKVMLVRHR----SSMKLYAIKSIQKRKLLDAMKS----HTVIAERNILMKA-HHPFIVQLFFAFQ-----NPSKFYLGLEYVPGGEL
  ....||.||||.|.. . .    .     |.|.. |    .||..       ..| .|...  ||| ||.|  .       |  . |. .||.|.| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE---GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN--QIYIVMEYMPHGDL

FYHLTK----RGTFPINEVRLYSAEIALALSYLHSIGIIYRDLKPENVMLDSTGHIKLTDFGLS
  .| |    .. ... .   ....|| ...||.|...| |||   |.........| .||||.
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 90149.m00309.AA S_TK_X 372-425 27 1.2e-05 25.47 SMART 1-79 (79) Show / Hide 
Range on Protein: 372-425
Range on HMM: 1-79/79
Sequence Identity: 27% (22 aa)

KGIDWDKVYN--REYQPNFIPKQT--------TPNCDSVFLQ----ESPADSIVTATSAQ-----------FPDFSFQG
.||||||.||  .|..| |.|| .        | | |  |      ..|.|....... |           |..|..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 90149.m00309.AA Pkinase_Tyr 354-369 37 0.713649 3.58 Pfam 255-270 (270) Show / Hide 
Range on Protein: 354-369
Range on HMM: 255-270/270
Sequence Identity: 37% (6 aa)

KNPNQRPDFSGIKDHV
..|..|| || |  . 
YDPEDRPTFSEIHEQL
Kinase 90149.m00309.AA Pkinase_Tyr 293-311 52 2.176188 1.94 Pfam 190-208 (270) Show / Hide 
Range on Protein: 293-311
Range on HMM: 190-208/270
Sequence Identity: 52% (10 aa)

KYTHKIDWWSLGILMYEMI
|.|.| | || |.||.|..
KFTTKSDVWSFGVLMWEIF