Gene 86756.m00093 (T.vaginalis)

86756.m00093

Species: T.vaginalis
Alias: TvagK0391, 86756.m00093
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
86756.m00093.AA Protein None 469 None Fasta, JSON
86756.m00093.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 86756.m00093.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 86756.m00093.AA PH 40-134 36 2.3e-20 76.09 Pfam 1-92 (92) Show / Hide 
Range on Protein: 40-134
Range on HMM: 1-92/92
Sequence Identity: 36% (35 aa)

VIHSGWGTKLGAIFKTWRYRWFVLTQTSLSYSKTKTSAPNGIINLSQVSEVAPMPECIHPHAFKVVIPNVRTYQIFVESDEAMNEWVRVLNKVLG
||..|| .|.|  .|.|. |||||... |.| | ... | |.|.|| . .| . |.  .|| |.... . ||| .. ||.| ||.|.. ..... 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 86756.m00093.AA PH 40-136 32 3.3e-17 64.41 SMART 1-82 (82) Show / Hide 
Range on Protein: 40-136
Range on HMM: 1-82/82
Sequence Identity: 32% (32 aa)

VIHSGWGTKLGAIFKTWRYRWFVLTQTSLSYSKTKTSAPNGIINLSQVSEVAPMPECIHPHAFKVVIPNVRTYQIFVESDEAMNEWVRVLNKVLGGK
||..|| .|..  . .|. |||||.  .|.| | |  .| |.|.|| . .| . |      .|...  .  || .. ||.| |.||.. ..|..   
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 86756.m00093.AA AGC 146-403 33 3.1e-169 441.8 In-house 1-395 (395) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-395/395
Sequence Identity: 33% (133 aa)

FDILKVLGKGSYGKVQLVKHK------GTNQIYAMKSISKRL-LGEYE--LVSRIITE------------RDVLLKIN----------HPFLVS-ARYAF
|..|||.||||.||| ||..|      .|...|||| ..|.    . .   | ...||            |..| |.|          |||.|.   |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTETK--IFLVLDYVQ---------GG-ELFSRLR---EERKFVEERARYYIAE-------LAHAIGYLHS-MGICHRD-LKPENILFDKDGYIKLTDFG
|....  ...|..|..         || |||..|.    |..| |||||.|.||       .. |. |||| ||| ||| |||||||.|.||.|||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LVKEQMTKD--------------------------------------------------ATTTTFCG--TPEYLAPEMVAGNAYDNNVDWWA--LGTLSY
| || |...                                                  ..|.||||  ||||.|||..    |.  .|||.  || | |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLYGVPPFYDVN----------TNAMYRSIL------RDDIVFP----------EDATEDAIDFIQKLLDKNPTTRLGSGPED-----YKEVIGHKFF
|||.| ||||. |           . |. .|.       ... ||          .  ...| |.|.||| |.|. |||.|..|     ..|.  |..|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 86756.m00093.AA SGK 146-403 45 5.5e-144 447.8 In-house 1-283 (283) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-283/283
Sequence Identity: 45% (130 aa)

FDILKVLGKGSYGKVQLVKHKGT------------------NQIYAMKSISKRLLG-------EYELVSRIITER-DVLLKINHPFLVSARYAFQTETKI
||.|||.||||.||| .||||..                   ..|||| ..|             ...  | .|| ..| ...|||.|. .|||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FLVLDYVQGGELFSRLREERKFVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGN
..|.|||.|||.|. |. |..| | ||| | ||.. |..||||  | .||||||||| | .|...|||||| ||.. .  ||.||||||||||||. .. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

AYDNNVDWWALGTLSYEMLYGVPPFYDVNTNAMYRSILRDDIVFPEDATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
 .|. |||| ||.. |||.|| ||||. |.. ||  |.. .. .|   . || | || || |.|. |||.  .|  |.  | ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 86756.m00093.AA Akt 146-403 50 4.6e-143 460.22 In-house 1-264 (264) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-264/264
Sequence Identity: 50% (132 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIY-AMKSISKRLLGEYELVSRIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEE
||.||||||||.||| ||| | |...| |||...|. . .   |  ..||| .| ..||||.|.  |.|||..|...|.||..|||||. |. .|.| |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RARYYIAELAHAIGYLHSMGICHRD-LKPENILFDKDGYIKLTDFGLVKEQ-MTKDATTTTFCGTPEYLAPEMVAGNAYDNNVDWWA-LGTLSYEMLYGV
|||.|.||.  ||..|||..|  || ||||||| ||||.|.|||||| ||  .. . .|.||||||||||||.  || ..  ||||. || . |||..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDVNTNAMYRSILRDDIVFP--EDATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
||||. .   |.  |.  .. ||  .    .. |.| .|| |.|. |||.||.| .|.  | .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 86756.m00093.AA AktR 146-403 44 4e-117 395.41 In-house 1-268 (268) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-268/268
Sequence Identity: 44% (120 aa)

FDILKVLGKGSYGKVQLVKHK-GTNQIYAMKSISKRLLGEYELVSRIITERDVLL-KINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVE
|...|.|||| .||| ||..|  ....||||.|.|  . |... ...||||...  ..||||.|   |.|||..|.|....|..|||||. |. ..|| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ERARYYIAELAHAIGYLHSM-GICHRDLKPENILFDKDGYIKLTDFGLVK-EQMT-KDATTTTFCGTPEYLAPEMVAG-NAYDNNVDWWALGTLSYEMLY
|.|| |.|.   |. |||.   |  ||||||||| |.||..|.||||| | . |  .| ....|||||||.||||.     .. .|||||.|.. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVPPFYDVNTNAMYRSILRDD---IVFPEDATEDAIDFIQ-KLLDKNPTTRLGSGPEDYKEVIGHKFF
| ||||. |.| |. .|.  .   . .|.. .. . |.|| |||.|||. |||.. .. .|.  |..|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 86756.m00093.AA RSK 149-403 42 1.1e-110 374.02 In-house 1-278 (278) Show / Hide 
Range on Protein: 149-403
Range on HMM: 1-278/278
Sequence Identity: 42% (118 aa)

LKVLGKGSYGKVQLVKHK---GTNQIYAMKSISKRLLGEYEL-VSRIITERDVLLKIN-HPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERK---
|||||.|.|||| |.. .    |.|||||| ..|. .   .  . .  |||..|. .. |||.|.  ||||||.|..|...|. ||||| .|..|.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDK---DGYIKLTDFGLVKE-QMTKDATTTTFCGTPEYLAPEMVA----GNAYDNNVDWWALGT
| |..|..|.||.. |. .||. || ||||||||||.|    .| |||||||. |.    .   | |||.| ||.||||..    ....| ..||| || 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LSYEMLYGVPPFYD---VNTNAMYRSILRDD--IVFP--EDATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
| |||| | |||.     | .   . |.. .    .|  .  ...| |.|.|.| ..|  |||.||.| .|.  |..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 86756.m00093.AA PKA 146-403 42 1.7e-108 366.74 In-house 1-263 (263) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-263/263
Sequence Identity: 42% (114 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITERDVLLKINHPFLV-SARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEE
|.|...||.||.|.|.|..||.. ..|||| ..|.       | ....|. .|. |.|||.| .  . ||.......|..||.|||.||.|| ...| . 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RARYYIA-ELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGN-AYDNNVDWWALGTLSYEMLYGVP
 |. |.| .   |. ||||. | .||||||||| ||.|.||.|||| .|.  ..|  | | ||||||||||.. .   .   ||||||| | |||| |.|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKK--VDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYDV--NTNAMYRSILRDDIVFPEDATEDA---IDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
||||   .....|. |.  .| ||.  . ||    |.| ||| ...| |.|.  ..   .  ||.|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 86756.m00093.AA PKC 146-403 42 3.9e-106 345.05 In-house 1-262 (262) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-262/262
Sequence Identity: 42% (111 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITERDVL-LKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEE
|. ||||||||.||| |...|||...||.| . | .  . . |    ||. || |  .||||..    |||. ..| |. ||.|| |     . |.| ||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGNAYDNNVDWWALGTLSYEMLYGVPPF
.|| | || . |  .||. ||  |||| .|.| |..| ||..|||. ||.|....||.||||||.|.||| ...  |  .|||||.| | |||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDVNTNAMYRSILRDDIVFPEDATEDAIDFIQKLLDKNPTTRLGSGPED---YKEVIGHKFF
  ..   . .||. |....| . ...| . ......|||..|||..|..    ...  | ||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 86756.m00093.AA RSK-Unclassified 146-403 35 1.2e-101 320.15 In-house 1-283 (283) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-283/283
Sequence Identity: 35% (101 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLR--EERKFVE
|   . .|.|. ||| ||. |.|.||||||  .|  .    .. ...||....   |||| |   ..|||. . .|...|  ||..|  |    |..| |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

ERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQ---------------------MTKDATTTTFCGTPEYLAPEMVAGNAYD
...|.|..|   |  |||  ..  |||||.||. ...| ..||||.| ..                      .     |  |||| |||||||. ..   
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

NNVDWWALGTLSYEMLYGVPPFYDVNTNAMYRSILRDDIVFP--EDATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
  |||| || . |||| |.||.|  |.| ..  |.. .. ||  .    .. | | ||| .||  |||..  |  ..  | ||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 86756.m00093.AA S_TKc 146-403 35 8.99999999999e-101 342.01 SMART 1-231 (231) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQG--GELFSRLREERK---
..||...|||..||| ...||.|..|.|.| |.           .|. |...| | .||..|   ..||. .....|..|. |  |.||..... ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGNAYDN-NVDWWALGTLSYE
   | | .||.|..... |. |.||.||.||||||||||.|.   ||..|||| ..        |||||||.|.|||..    |.   .|||..| . ||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLYGVPPFYDVNTNAMYRSILRDDIVFPEDATEDAIDFIQKLLDKNPTTRLGSGPEDY--KEVIGHKFF
||.| |||.  . ..|.. |.          ...|.|||.|.|.|.|. |..         ..  | .|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 86756.m00093.AA RSK 146-403 36 1.6e-91 310.39 In-house 1-271 (271) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-271/271
Sequence Identity: 36% (99 aa)

FDILKVLGKGSYGKVQLVKHK---GTNQIYAMKSISKRLLGEYELVSRIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFV
.......|.||..|| ..| .    ||| |||| | |  .   .   .  .||..|  ..||| |  .|.||.|.|.....|  .||.|| ||  .. | 
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKD----GYIKLTDFGLVKEQMTKDATTTTFCGTPEYLAPEMVAGNAYDNNVDWWALGTLSYEML
|. .. | ||.| |  |||| || ||||||||||.| .    | ||..|||. |.   ..  . |||.| .|.|||..    .|  .||| .|.| ||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

YGVPPFYDVNTNAMYRSILRDDIVF-------PEDATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
 | .||.  . . .   |.| . .        ..  .. | | . ..|. .|. |||.||.. ...  |..|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 86756.m00093.AA p70 190-403 41 5.5e-90 305.25 In-house 74-299 (299) Show / Hide 
Range on Protein: 190-403
Range on HMM: 74-299/299
Sequence Identity: 41% (94 aa)

RIITERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGGELFSRLREERKFVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFG
|   || .|  ..|||..   |||||. | .|.|.|  |||||  | ..  . |. |..| .|   |...||. ||  |||||||.. .. | ..|||||
RTFAERNILEEVKHPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFG

LVKEQMTKDAT----------TTTFCGTPEYLAPEMVAGNAYDNNVDWWALGTLSYEMLYGVPPFYDVNTNAMYRSILRDD--IVFPEDATEDAIDFIQK
| ||.. ..|           | |||||.|| |||.. . ... .||||.|| | | || |.|||   |      .||.    .  |   |... | |.|
LCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKK

LLDKNPTTRLGSGPEDYKEVIGHKFF
|| ..||.|.|.|||| ...  |.||
LLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 86756.m00093.AA Pkinase 146-403 31 2.9e-87 301.0 Pfam 1-293 (293) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRII-TERDVLLKINHPFLVSARYAFQTETKIFLVLDYVQGG----ELFSRLR--EE
. |....|.||.|.| . .||||..|.|.| |.||   . ......  .|  .....|||. |  ...|.....| .|..|..||    .||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RKF--VEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYI----KLTDFGLVKEQ-MTKDATTTTFCGTPEYLAPEMVA-GNAYDNNVDWWAL
..|   |. .. |. ... .. |.|||||.||||||||||.|..|.|    |..|||| |     ..  .|||||||.|.||| .  |. |.  ||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GTLSYEMLYGVPPFYDV------NTNAMYRSILRDDIVFPEDAT---------------------EDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
| . |||| | |||..       . ..|.. |.. .. |... .                     |...||| ..|.|.|. |..      ...  |..|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 86756.m00093.AA S_TK_X 404-467 36 2.6e-15 58.13 SMART 1-79 (79) Show / Hide 
Range on Protein: 404-467
Range on HMM: 1-79/79
Sequence Identity: 36% (29 aa)

ASINFDQLLK--KQIPMQWKPQIS----SNTDVSAFDREFTTEKPKLTYEDPSLIGQNVQRQ---------LQGFTYMN
..|..|.|..  |.|.  .||.|.    | ||.| || ||| |.|.||  || |.... |..           ||||..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 86756.m00093.AA TyrKc 146-403 18 1.7e-13 -4.44 SMART 1-280 (280) Show / Hide 
Range on Protein: 146-403
Range on HMM: 1-280/280
Sequence Identity: 18% (55 aa)

FDILKVLGKGSYGKVQLVKHKGTNQIYAMKSISKRLLGEYELVSRIITERDVLLKI--NHPFLVSARYAFQTE-------TKIFLVLDYVQGGELFSRLR
   .|.|| | .|.| . . |   .  | |.. .        .  .. |  .. |.  .|| .|    .  ..         ...|. |. .| | ..||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EERK-FVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTK-------DATTTTF--CGTP----EYLAPEMVAGNAYD
. |. .  .   ..    |    ||||... ||||   |.| .... .| .|||| ..   .       |  ...   .|        .|||    . . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NNVDWWALGTLSYEML-YGVPPFYD-----VNTNAMYRSILRDDIV-FPED--------ATEDAIDFIQKLLDKNPTTRLGSGPEDYKEVIGHKFF
   | |. | . .|.. || .| ..     ..   ... . . .    |..        ....  . ...  . .|  |        .|.  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEI--HECF
Kinase 86756.m00093.AA p70 146-180 52 2e-12 41.42 In-house 1-38 (299) Show / Hide 
Range on Protein: 146-180
Range on HMM: 1-38/299
Sequence Identity: 52% (20 aa)

FDILKVLGKGSYGKVQLVKHKG---TNQIYAMKSISKR
|  ||||||| |||| .|.      |..||||| . |.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKA
Kinase 86756.m00093.AA Pkinase_C 423-469 42 4.3e-12 45.84 Pfam 1-46 (46) Show / Hide 
Range on Protein: 423-469
Range on HMM: 1-46/46
Sequence Identity: 42% (20 aa)

QISSNTDVSAFDREFTTEKPKLTYEDPSLIGQNVQRQLQGFTYMNEE
|..| ||.| || ||| |.|..|. |.. . .. |.. .|||| |..
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase 86756.m00093.AA Pkinase_Tyr 146-303 22 1.2e-08 29.95 Pfam 1-171 (270) Show / Hide 
Range on Protein: 146-303
Range on HMM: 1-171/270
Sequence Identity: 22% (38 aa)

FDILKVLGKGSYGKVQLVKHK----GTNQIYAMKSISKRLLGEYE-LVSRIITERDVLLKI-NHPFLVSARYAFQ-TETK--IFLVLDYVQGGELFSRLR
  ..|.||.|..|.| . . |    .|..  | |.. |    . . .    . |  .. .. .|| .|.   .    .    |..|. |...| | . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----ERKFVEERARYYIAELAHAIGYLHSMGICHRDLKPENILFDKDGYIKLTDFGLVKEQMTKDAT-TTT
.    ....  ..   . .. | .  ||.|... ||||   |.| .... .| .|||| .  . .|   ...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKR