Gene 83472.m00486 (T.vaginalis)

83472.m00486

Species: T.vaginalis
Alias: 83472.m00486, TvagK0278
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
83472.m00486.AA Protein None 869 None Fasta, JSON
83472.m00486.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 83472.m00486.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83472.m00486.AA TKL 27-274 24 1.7e-81 277.05 In-house 1-364 (364) Show / Hide 
Range on Protein: 27-274
Range on HMM: 1-364/364
Sequence Identity: 24% (93 aa)

IGEGAFGLVYLGIHKR--------TGLKCAVKKLITDELEGNEL-----------------------VYFCREVKILACCH--SYFLVPLLGFTYTSP--
||.|.|| || |...         ||   ||||. ...   ...                         |..|. |. .       .|...|.   .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YLIITEFIECGTLFSALHHKPGSPNLTNTEKCVIAMCIAHGMMNLHKMK--------IIHRDLKSLNILLDNRHL-------------
            . |..|....|.|.. ||            .| .|. || ||  || |.        |||||||| |||.|.                
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKVIDFGIARFKDDSTN-------------------LVTQQIGTTQWMAPEQLMTA----------------TYTNKVDVYAYGVLLWEIVSEDIPFR-
 .|. |||..||.. |.|                       |.||..||||| |. .                .|. |.|||..|..||||..  .|.. 
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

-GFTGVQIA-------IQVAERNSRPKIT------------DNCPKKLRQLIELCWHRDPEKRPSFKQIFHSF
 ..  ....       ..|.... || |             ..||. ...|.. ||. ||||||||..| . .
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 83472.m00486.AA TKL-Unique 23-274 32 8e-79 268.17 In-house 1-290 (290) Show / Hide 
Range on Protein: 23-274
Range on HMM: 1-290/290
Sequence Identity: 32% (95 aa)

LVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGNELVY-FCREVKILACCH-SYFLVPLLGFTY----TSP-YLIITEFIECGTLFSALHH-----
 ..|||||..| || |.....  . |.|..   |.  ||..  | .||... . | . ..| . |..     . | . |..|... |.| . ||      
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---KPGSPNLTNTEKCVIAMCIAHGMMNLHKMK--IIHRDLKSLNILLDNR-----HLPKVIDFGIARFKD-DSTNLVT--------QQIGTTQWMAPEQ
   .. .. |..  .  .| .|| || .||  .  ||||||||.|.|.||.        |..|||...|.. .... ..          .|...||||| 
NNNNNNCK-LNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LMT--ATYTNKVDVYAYGVLLWEIVSEDI------PFRGFTGVQIAIQVAE--RNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHSF
|.   ..|..|.|||..|. ||||.. .|      |..|..  |..  |..  .|.||.| ..||| .| ||. |||.||..|||| .| |. 
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
S_TKc 83472.m00486.AA S_TKc 21-275 26 4.1e-63 216.91 SMART 1-231 (231) Show / Hide 
Range on Protein: 21-275
Range on HMM: 1-231/231
Sequence Identity: 26% (72 aa)

FDLVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGNELVYFCREVKILACCHSYFLVPLLGFTYTSPYLIITEFIEC--GTLFSALHHKPGSPN--
.....|||.|||| ||...||.|| ..|.|..            ..||..||   |  ..| |... ... . ...|...   |.||. ...... ..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LTNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIARFKDDSTNLVTQQIGTTQWMAPEQLMTATYTN-KVDVYAYGVLLWEIV
 ..  . . ..  |. ..  .|...|||||||  |||||.    |..|||.||.        | ..||  .|||| |    |.  |.|... |..|.| .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

SEDIPFRGFTGVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIF--------HSFA
.   ||.    .|  ...             .. ....|. |...||||||.  ...        | . 
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83472.m00486.AA MLK 21-274 29 8.1e-61 208.36 In-house 1-291 (291) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-291/291
Sequence Identity: 29% (86 aa)

FDLVKKIGEGAFGLVYLGIHKRTG---LKCAVKKLI-------TDELEGNELVYFCREVKILACCH-SYFLVPLLGFTYTS-P-YLIITEFIECGTLFSA
... ..||.|.|| |..|  . .       |||.           . |  ..  .||...||     .   ....|    . . ..|..|..|.| |.. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHHKPGSPN-----------LTNTEKCVIAMCIAHGMMNLHKMK---IIHRDLKSLNILLD-------NRHLPKVIDFGIARFKDDSTNL-VTQQIGTTQ
|| ... ..            .   .  .|. .|.||  ||.|.   |||||||| |||.|       ...| |. |||..|.. ...    . ..||  
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTL-KICDFGTSRDWHQMC-TNMMSNAGTYA

WMAPEQL---MTATYTNKVDVYAYGVLLWEIVSEDIPFR-GFTGVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHSF
||||| .      .|. |.||. .||.|||...  .|.. .  . .||..||. . || |  .||. . .|.. ||. ||.|||||.||   .
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 83472.m00486.AA Pkinase_Tyr 21-274 32 6.7e-58 196.72 Pfam 1-270 (270) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-270/270
Sequence Identity: 32% (88 aa)

FDLVKKIGEGAFGLVYLGIHK----RTGLKCAVKKLITDELEGNE--LVYFCREVKILACC-HSYFLVPLLGFTY--TSP--YLIITEFIECGTLFSALH
  . ||.|||||| ||.|. |     |....|||.|  .     .  .  | ||.||.    |   .| |.|  .    |  ..|..|. ..| | . |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

HK-PGSPNLTNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIARFK--DDSTNLVTQQIGTT--QWMAPEQLMTATYTNKVDVY
 . .. ..||  ... ... || ||  |. ...|||||   |.|... .  |. ||| ||    ||   ..... |     ||||| ...  .| | ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVW

AYGVLLWEIVS-EDIP-FRGFTGVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHSF
..|||.|||..  ..| . | .  ..  ...|.. | .. .|||... .|. .||| |||.||.|..| . .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 83472.m00486.AA Pkinase 21-274 26 9.3e-58 203.0 Pfam 1-293 (293) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-293/293
Sequence Identity: 26% (79 aa)

FDLVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGNELVYFCR--EVKILACCHSYFLVPLLGFTYTSPYLI-ITEFIECG----TLFSALH---H
. ...|||.|.|| ||...|| || . |||..  .. . .....  |  |..|.. ... . | |... ......  ..|. |.|     ||. ..   |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KPGSPNL--TNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLP----KVIDFGIARFK-DDSTNLVTQQIGTTQWMAPEQLM-TATYTNKVD
..    .  .  | . ..  |. |.  .|.|.|||||||. |||.||.  .    |..|||.|...   .    |   ||  .|||| ..    |. |||
GC----FYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYAYGVLLWEIVSEDIPFRGF---TGVQIAIQVAERNSRPKITDNCP-----------------------KKLRQLIELCWHRDPEKRPSFKQIFHS--F
....|..|.| ..   ||.|     .    .|. .|. .|..  ..|                       . ....|. |...||.|||...||...  |
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83472.m00486.AA Dicty4-Unclassified 21-274 35 3.2e-56 191.02 In-house 1-263 (263) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-263/263
Sequence Identity: 35% (94 aa)

FDLVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGN--ELVYFCREVKILACCHSYFLVPLLGFTYTSP------YLIITEFIECGTLFSALH---
    . ||.|.|  |. |. |  |   ||||.           .  | .|| ||       || . |     |      . |..||.  |.||   |   
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKP

-HKPGSPNLTNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIARFKDDSTNLVTQQIG-TTQWMAPEQLMTATYTNKVDVYAYG
  .  .  |  |    .|. || ||  ||   .||||.|| |||.|     |. ||||.|  |   |. |  |. |  | .|| ||   |. | ||| |.
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTT--IAGTPKWESPECLMHESYNQKSDVYSYA

VLLWEIVSEDIPFRGFT-GVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHSF
..|.| .  | |. .    . .|. |...  |||| |||.  ...||  ||| || |||.. ||    
MMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 83472.m00486.AA LRRK 80-276 32 2.9e-51 176.64 In-house 119-351 (351) Show / Hide 
Range on Protein: 80-276
Range on HMM: 119-351/351
Sequence Identity: 32% (76 aa)

LVPLLGFTYTSPYLIITEFIECGTLFSALHHKPGSP------NLTNTEKCVIAMCIAHGMMNLHKMK--IIHRDLKSLNILL---D---------NRHLP
.|.|.||.  .|. ...|.. .|.| . ||.|  ..      ... . |  ||. || ||  ||. .  |||||||| ||||   .         .    
IVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCA

KVIDFGIAR-FKDDSTNLVTQQIGTTQWMAPEQLM---TATYTNKVDVYAYGVLLWEIVSED-IPFRGFTGV---QIAIQVAE---RNSRPKITDN-CPK
|..|||| | |. . . ..    |. .||||| .    . .|| |||.|..|..|||... . .||......   |  .|. .   .  ||.|  . || 
KIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYCPP

-----KLRQLIELCWHRDPEKRPSFKQIFHSFAT
      . .||..||. ||.|||.| ||.    .
CQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 83472.m00486.AA TK 21-274 17 3.4e-51 169.45 In-house 1-486 (486) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

FDLVKKIGEGAFG---LVYLGIHKRTG-------------------------LKCAVKKLITD-ELEGNELVY--------------FCREVKILAC--C
  |.||.|||.||    ||.|. .. .                          ..||| |  . . . .|                 ...| |.. .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HSYFLVPLLG-FTYT------------SPYLIITEFIECGT----LFSALH-HKPGSPN-----------------------------------------
|   .| |.|  |               |..|..|. ..|     | . |. ..|.  .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LTNTEKCVIAMCIAHGMMNLHKM------KIIHRDLKSLNILLDNRHL-----------PKVIDFGIA-
                               ||  ... ... || ||  ||..      ...||||   |.|.....             |. ||| . 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RFKDDSTNLVTQQIGTTQ--------------------------WMAPEQLM---------TATYTNKVDVYAYGVLLWEIVSED-IPFRG-F
       |  ..... .... ..|                           ||||| |.         . ..| | ||...|||.|||..    |. |  
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TG--------VQIAIQVAERN--------------SRPKITDNCP--------------KKLRQLIELCWHRDPEKRPSFKQIFHSF
.         .|  ..  .|                |..  ..||              . . .|.  |||.|||.||.|.|. . .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 83472.m00486.AA TyrKc 21-274 29 6.2e-50 173.12 SMART 1-280 (280) Show / Hide 
Range on Protein: 21-274
Range on HMM: 1-280/280
Sequence Identity: 29% (85 aa)

FDLVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGNELVYFCREVKILACC--HSYFLVPLLGFTYT--------SPYLIITEFIECGTLFSALHH
  | ||.|||||| ||.|. |   ...|||.|  |      .  |.|| .|.     |   .| |.|   .         |..|..|. . | | . |. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

KPGSPNLTNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIARFKDDS------TNLVT-----QQI--GTTQWMAPEQLMTATY
. .   |.. ... ..  || ||  ||....|||||   |.|....|  |. ||| .|. .|       .   .     .        ||||| ... ..
HRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TNKVDVYAYGVLLWEIVSE-DIPFRG-----FTGVQIAIQVAERNSRPKITDN-------CPKKLRQLIELCWHRDPEKRPSFKQIFHSF
| | ||...||..||| .  . |  |      .  ..  .| ... .|.  ..       ||... |... |||.|||.||.|..| . |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 83472.m00486.AA Dicty4 93-276 34 7.3e-50 164.56 In-house 78-277 (277) Show / Hide 
Range on Protein: 93-276
Range on HMM: 78-277/277
Sequence Identity: 34% (69 aa)

LIITEFIECGTLFSALHH------KPGSPNLTNTEK-CVIAMCIAHGMMNLHK--MKIIHRDLKSLNILLDNRHLPKVIDFGIAR-FKDDSTNLV--TQQ
.| ||.   |.|.| ||       .  .. ..  ..   .|  .| ||  ||     |||||||| |.| |     || |||... .| ....    . .
CIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA

IGTTQWMAPEQLMTATYTNKVDVYAYGVLLWEIVSEDIPFR--GFTGVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHS--FAT
.||. ||||| .|   |. |.||| .| .||||.  ..|.   .   .|... |..   ||.| |.||.....||. ||. ||..||||..|       .
CGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 83472.m00486.AA STE 21-275 20 2.7e-49 170.09 In-house 1-359 (359) Show / Hide 
Range on Protein: 21-275
Range on HMM: 1-359/359
Sequence Identity: 20% (75 aa)

FDLVKKIGEGAFGLVYLGIHKR---------------TGLKCAVKKLITDELE---------------GNELVYFCREVKILACCH--SYFLVPLLGFTY
.....|||.|||| ||.....                ||  .|.|..  .. .                .|.  . .|.||. .|.  . . |  .|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TSP--------YLIITEFIECGTLFSALHHKPGSPN-LT----------NTEKCVIAMCIAHG-MMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIAR
             |. |... |.| . ..|| | .. |.           .. ..|.  | .| .  ||...|||||.|. ||||      | .|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FKDDS--------------TNL-VT-QQIGTTQWMAPEQLMT------ATYTNKVDVYAYGVLLWEIVSEDIPFRGFTGVQIAIQVAER-----------
  .||              |.   .   .||  ||||| ..         |. |.|..  | ...| .    |.  ..  .   . .             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---NSRPKITD-------------------NCPKKLRQLIELCWHRDPEKRPSFKQIF---HSFA
   .  |.. |                   .. ..... |..|  .||.|||. .|     |.| 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 83472.m00486.AA HH498 65-274 32 3.9e-49 153.69 In-house 49-284 (284) Show / Hide 
Range on Protein: 65-274
Range on HMM: 49-284/284
Sequence Identity: 32% (77 aa)

FCREVKILACCHSYFLVPLLGFTYTSP--YLIITEFIECGTLFSAL--------------HHKP-GSPNLTNTEKCVIAMCIAHGMMNLHK---MKIIHR
||||| |.    .   |  .. .   |   .|.|.... | ||| |              |       ..    |  |.. .||||  ||      ||||
FCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHR

DLKSLNILLDNRHLPKVIDFGIARFKDD-STNLVTQQIGTTQWMAPEQLM-TATYTNKVDVYAYGVLLWEIVSEDIPFRGFTGVQIAIQVAERNSRPKIT
|| | |||..     .| |||. ||. |      | |.|   |||||       |. ||||. |.  .||. .  .||  .  .  |  .| .  || | 
DLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIP

DN----CPKKLRQLIELCWHRDPEKRPSFKQIFHSF
       |..   ||  |||  || ||.| ||    
QTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 83472.m00486.AA Dicty5 23-278 33 4.7e-49 166.98 In-house 3-260 (260) Show / Hide 
Range on Protein: 23-278
Range on HMM: 3-260/260
Sequence Identity: 33% (87 aa)

LVKKIGEGAFGLVYLGIHKRTGLKCAVKKLITDELEGNELVYFCREVKILACCH--SYFLVPLLG-FTYTSPY-LIITEFIECGTLFSALHHKPG--SPN
. . |  || | || || |  |   |.| .  .   . ... | ||| |.         ..  .|  .|   |  ..||..  |.||..|  .      .
FHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LTNTEKCVIAMCIAHGMMNLHKMKIIHRDLKSLNILLDNRHLPKVIDFGIARFKDDSTNLVTQQIGTTQWMAPEQLMTATYTNKVDVYAYGVLLWEIVSE
.    .  .|. || .|  || | ||||||||.|.|.  .   |.||||. || |   .  |  .||  |||.|     .|..|.|||..|. |||.   
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHM-TMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTR

DIPFRGFTGVQIAIQVAERNSRPKITDNCPKKLRQLIELCWHRDPEKRPSFKQIFHSFATHK
. |.   .   |.. |.    || |   ||     ||. ||   | .||||| |   |    
KEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 83472.m00486.AA LRRK 21-78 15 5e-06 17.26 In-house 1-101 (351) Show / Hide 
Range on Protein: 21-78
Range on HMM: 1-101/351
Sequence Identity: 15% (16 aa)

FDLVKKIGEGAFG-LVYLGIHKR-----------------------TGLKC---AVKKLITD---------ELEG--------NELVYFCREVKILACCH
.   ..||.|.|| .|| .. ..                       . ..|   |.||...|           ..        .| |..  .. .  ||.
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCR

SY
..
AF
Kinase 83472.m00486.AA Dicty4 21-73 36 7e-06 15.77 In-house 1-53 (277) Show / Hide 
Range on Protein: 21-73
Range on HMM: 1-53/277
Sequence Identity: 36% (20 aa)

FDLVKKIGEGAFGLVYLGIHKRTGLKCAVKKL--ITDELEGNELVYFCREVKILA
 .  ..||.|.|| ||.|. .  | . |||||    . .. |.|  | .||.|..
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMC
Kinase 83472.m00486.AA HH498 21-38 50 0.000127 10.14 In-house 1-18 (284) Show / Hide 
Range on Protein: 21-38
Range on HMM: 1-18/284
Sequence Identity: 50% (9 aa)

FDLVKKIGEGAFGLVYLG
.   .||| |.|| ||.|
IEFHEKIGSGSFGKVYKG