Gene 95912.m00292 (T.vaginalis)

95912.m00292

Species: T.vaginalis
Alias: 95912.m00292, TvagK0436
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
95912.m00292.AA Protein None 428 None Fasta, JSON
95912.m00292.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 95912.m00292.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 95912.m00292.AA PH 8-104 18 3.4e-07 31.16 SMART 1-82 (82) Show / Hide 
Range on Protein: 8-104
Range on HMM: 1-82/82
Sequence Identity: 18% (18 aa)

FAIKGWISQKTNLYRSDRKLYGVVTEEDFTTYQDEQQKILYKNINLNEIKLVSQLTGARPGFSITLENSKDELIFYCPSKHQAQKWICALQLKPVDT
. ..||...|.    . .| . |...  .. |.|.    . . |.|......        .| |.  .   ...|.|.|. ..|.|. |.|    . 
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDCTVRE-P-----CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 95912.m00292.AA AGC 111-365 26 7.6e-128 332.29 In-house 1-395 (395) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-395/395
Sequence Identity: 26% (107 aa)

FDYIKEIGRGGNAIVYVARNR------LKDELVAIKTIEKAH-ISTDK--HREHIQSE------------RNTLMRAR----------HPFIIH-LFNAF
|. .| ||.|.   || .| .        ... |.| ..|.| |  .|    ||...|            || |....          ||||.. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTNTH--LLFVLE----FAF-----GG-DLHFQLSK--NLCSIDNFQKKLYLAE-------IALAVKYLHS-LGIIYRD-LKPENILLDSRGHIKLADFG
|...|  | ||.|    ..      || .|...| .  .  . |  . . |.||       |.||. |||| .|||.|| |||||||||..|||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TARQCTSQ-----------------------------------------------------CNSFCG--TAEYLAPEIISKSSSQTFAIDWWS--FGIVA
 . .  .                                                      ...|||  |.||.||||.      ..| ||||  .|.. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YCLYTGSVPFSNNN---------NRKMLFDAIC------QKPVRIP----------KSMDPVLADFLTRLLEKNPAKRLGS-PG-------FDVFEHEFW
| . ||  ||...|         |.. .|. |.      ...|..|          ....| . |....||.|.|.||||. ..        .. .|.. 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 95912.m00292.AA S_TKc 111-365 33 6.5e-88 299.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-231/231
Sequence Identity: 33% (89 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQSERNTLMRARHPFIIHLFNAFQTNTHLLFVLEFAFG--GDLHFQLSKNLCS--
.. ...||.|. . || .|..  ...|||| |           |||..|.. |.. .||.|..|. .||. .|| .|.|.. |  |||.  . |. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IDNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFGTARQCTSQCNSFCGTAEYLAPEIISKSSSQTF-AIDWWSFGIVAYCLY
   ..  . . |...|..|..|.||.|||.|||||||||||.  |||..||| |||     ..|||| .|.|||..    . .. ..||||.|.. | ..
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGSVPFSNNNNRKMLFDAICQKPVRIPKSMDPVLADFLTRLLEKNPAKRLGSPGFDV-----FEHEFW
.|  ||.   . .|.|. |.          .| . ||. ..|.|.|.||..             |.. 
CGYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95912.m00292.AA Akt 111-365 37 3.1e-83 265.93 In-house 1-264 (264) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-264/264
Sequence Identity: 37% (100 aa)

FDYIKEIGRGGNAIVYVARNRLKDELV-AIKTIEKAHISTDKHREHIQSERNTLMRARHPFIIHLFNAFQTNTHLLFVLEFAFGGDLHFQLSKNLCSIDN
||..| .|.|  . |. ..    ...  |.| . | .|   .. ||.. ||| | . .||||. |  .|||...| ||.... ||.| . |..    .. 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRR-FSE

FQKKLYLAEIALAVKYLHSLGIIYRD-LKPENILLDSRGHIKLADFGTARQC-TSQ---CNSFCGTAEYLAPEIISKSSSQTFAIDWWS-FGIVAYCLYT
 . . | ||| ||  .||| .||||| |||||||.|. |||.|.||| ...   ..   ...||||.|||||||...   .| | |||. .|.| | ...
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMC

GSVPFSNNNNRKMLFDAICQKPVRIP--KSMDPVLADFLTRLLEKNPAKRLG-SPG--FDVFEHEFW
|  || |  ... .|. | ..||..|  .  .|   |....||.|.| ||||  |.   .. .|.. 
GRPPFYN-QDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 95912.m00292.AA SGK 111-365 35 1.6e-82 254.56 In-house 1-283 (283) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-283/283
Sequence Identity: 35% (103 aa)

FDYIKEIGRGGNAIVYVARNRLK------------------DELVAIKTIEKAHIS-------TDKHREHIQSER-NTLMRARHPFIIHLFNAFQTNTHL
||..| || |.   || ..   .                  | . |.| . |.||          |.  ||..|| . |   .||||. |  |||| . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

LFVLEFAFGGDLHFQLSKNLCSIDNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFGTAR---QCTSQCNSFCGTAEYLAPEIISK
 ||.... ||.. . | .  .     . . | |||..|  ||||. ||||||||||||||. ||..| ||| .    . .    .|||| ||||||.. |
YFVMDYVNGGEMFYHLQREKH-FPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRK

SSSQTF--AIDWWSFGIVAYCLYTGSVPFSNNNNRKMLFDAICQKPVRIPKSMDPVLADFLTRLLEKNPAKRLGSP--GFDVFEHEFW
   |..  . |||. |.| | . .|  ||  ..|.. ..| |  .| .||..| .   | .. ||.|.| ||||.   . .. .| | 
---QPHDRTVDWWCLGCVLYEMMYGLPPF-YSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 95912.m00292.AA Pkinase 111-365 28 2.4e-78 271.39 Pfam 1-293 (293) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-293/293
Sequence Identity: 28% (83 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQ-SERNTLMRARHPFIIHLFNAFQTNTHLLFVLEFAFGG----DLHFQLS-KNL
.  .. ||.|. . || ....   ..||.|.|.| |.. .|...|.  ||   . | .||.|. |. .|....|. .|.|.. ||    ||.  .| .. 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

CSI--DNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHI----KLADFGTAR---QCTSQCNSFCGTAEYLAPEIISKSSSQTFAIDWWSFG
...  .  . | |. .|. ...|.|| |||.|||||||||.|..|||    |..||| |.      .....|||| .|.|||.| ...  . ..|.||.|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNSMTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCG

IVAYCLYTGSVPFSNN-----NNRKMLFDAICQKPVRIPKSMD---------------------PVLADFLTRLLEKNPAKRLGSPGFDVFEHEFW
.. |....|  ||..      .. . ... | ..|.. . . .                     . . ||....|.|.|.||..    ....|...
CILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF
Kinase 95912.m00292.AA RSK 114-365 35 9.8e-77 261.24 In-house 1-278 (278) Show / Hide 
Range on Protein: 114-365
Range on HMM: 1-278/278
Sequence Identity: 35% (99 aa)

IKEIGRGGNAIVYVARNR---LKDELVAIKTIEKAHIST-DKHREHIQSERNTLMRAR-HPFIIHLFNAFQTNTHLLFVLEFAFGGDLHFQLSKNLCS--
.|. |.||.  |.. |      .. . | | ..|| | . .|  .|   ||| |.| . ||||..|. ||||...|  ..|.  ||.|   |.|  .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IDNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDS---RGHIKLADFGTARQ--CT--SQCNSFCGTAEYLAPEIIS---KSSSQTFAIDWWSFGI
..    . |.|||.|||..||..|||.|||||||||.|.   .||||| ||| ..|  |   .. ..||.|.||.|||..    . .  . | ||||.|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VAYCLYTGSVPFSN--NNNRKMLFDAICQKP--VRIP--KSMDPVLADFLTRLLEKNPAKRLGSP---GFDVFEHEFW
. | . || .|| .   |||| ... |...   ...|  ... .   |.....|...|.||||.      .. .|...
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 95912.m00292.AA AktR 111-358 38 1.2e-76 260.92 In-house 1-260 (268) Show / Hide 
Range on Protein: 111-358
Range on HMM: 1-260/268
Sequence Identity: 38% (100 aa)

FDYIKEIGRGGNAIVYVARNR-LKDELVAIKTIEKAHISTDKHREHIQSERNTLM-RARHPFIIHLFNAFQTNTHLLFVLEFAFGGDLHFQLSKNLCSID
|...| .|.|. . || .. .   ....|.| | | .|   . ..|.. ||| .   ..||||. |. .|||...| |..|.  ||.| . |.|.   ..
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKK-KKFS

NFQKKLYLAEIALAVKYLHSL-GIIYRDLKPENILLDSRGHIKLADFGTAR-QCTSQC----NSFCGTAEYLAPEIISKSSSQTFAIDWWSFGIVAYCLY
. | . | |.| ||. |||.   ||||||||||||||. ||.|..||| .. |         .||||| ||.|||.| |.   ....|||.|||. | . 
EEQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMV

TGSVPFSN-NNNRKMLFDAICQKPVRIPKSMDP--VLADFLT-RLLEKNPAKRLG--SPGFD
||  || . |.|.. ..  |.|  ...|.....   . |... .|| ||| ||||  ..|..
TGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWE
Kinase 95912.m00292.AA Ciliate-E2 111-365 21 7.7e-73 248.31 In-house 1-365 (365) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-365/365
Sequence Identity: 21% (81 aa)

FDYIKEIGRGGNAIVYVARNRLKDE-----------------------LVAIKTIEKAHISTDKHREHIQ----------SERNTLMRARHPFIIHLFNA
.. || ||.|. ..|| ........                       ..|.|...|  |   |  .||            |.| | .  ||.|| .. .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TNTHLLFVLEFAFGGDLHF-----QLSKNLC-----SIDNFQKKLYLAEIAL---------------AVKYLHSLG-IIYRDLKPENILLDSRGHI
||  ..... .|.|.. ||||       ....| .     ... .. | . ..|.                |..|||| . ||.||.||||||.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGTARQCTSQ----------------------------------CNSFCGTAEYLAPEIISKSSS--------QTFAIDWWSFGIVAYCLYTGSVP
|..|||...... .                                   |..|||..|.||||... .          ....|.||.|.. |.. .|  |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSNNNNRKMLFDAICQKPVRIP------------------KSMDPVLADFLTR----LLEKNPAKRLGSPGF-DVFEHEFW
|         .. |.|.....|                  |. ..   |.. .    .|.|.| ||..  |. ....|.. 
F---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 95912.m00292.AA PKA 111-365 35 1.4e-70 240.84 In-house 1-263 (263) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-263/263
Sequence Identity: 35% (93 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQSERNTLMRARHPFIIH-LFNAFQTNTHLLFVLEFAFGGDLHFQLSKNLCSIDN
|. |. .|.|  . |. .|..   . .|.|.. |. |   |. ||. .|.| |.  .||||.  .   ||....| .|.|.. ||.. |    .  . .|
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEM-FSYLRKSGRFSN

FQKKLYLA-EIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFGTARQCTSQCNSFCGTAEYLAPEIISKSSSQTFAIDWWSFGIVAYCLYTGSVPF
 . |.| | .| ||  ||||. ||||||||||||.|..||||..||| |  ...   . ||| ||||||||. .     ..|||..||. | . .|  ||
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDDRTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

SNNN-NRKMLFDAICQKPVRIPKSMDPVL---ADFLTRLLEKNPAKRLGSPGF---DVFEHEFW
...| .   ... ||.  .. | ..|. .    |.. .||.... ||.|.  .   |. .|.. 
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 95912.m00292.AA Ciliate-E2-Unclassified 111-353 25 2.1e-70 240.2 In-house 1-342 (352) Show / Hide 
Range on Protein: 111-353
Range on HMM: 1-342/352
Sequence Identity: 25% (88 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREH---------IQSERN-------------TLMRARHPFIIHLFNAFQTNTHLLFVL
.  || ||.||...|| .... .... |.|.. |..|  .|  ..         .  ...              |    ||||...| .||.  .. .|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFAFGGDLHFQLSK--------------NLC--SIDNFQKK-----LYLAEIALAVKYLHSLG-IIYRDLKPENILLDSRG---HIKLADFGTAR-----
|.. ||||.. ..|              ...   .. .| |      |.|.| .. .|||. . ||.||.||||||.|. |   .||..||| ..     
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---QCTSQ-----------CNSFCGTAEYL----APEIISK-SSSQT--FAIDWWSFGIVAYCLYTGSVPFSNNNNRK---------------MLFDAIC
   . |.|           ...|||| .|.    |||.. .   ...  ...|.||.|...|.. .|  ||. ||  .               .|.. |.
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

QKPVRIPK--------SMDPVLADFLT----RLLEKNPAKRLG
||.. .||          .|  .||..    ..|.||| ||..
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRIT
Kinase 95912.m00292.AA PKC 111-365 35 2.3e-69 223.94 In-house 1-262 (262) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-262/262
Sequence Identity: 35% (95 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQSERNTLMRA-RHPFIIHLFNAFQTNTHLLFVLEFAFGGDLHFQLSKNLCSIDN
|. .| .|.|  . |  |. . .||. ||| . |  |  |   |  . |.  |  | .|||  ||.  |||. .| ||.|.  |||| |.   .    . 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHI-QQQRRFKE

FQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFGTARQ---CTSQCNSFCGTAEYLAPEIISKSSSQTFAIDWWSFGIVAYCLYTGSV
 . . | |||..| ..||. |||||||| .|.|||. ||||.|||| . .     .  ..|||| .|.||||. .    ....|||.||.  | .  |  
EHARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEIL-QYQEYGKSVDWWAFGVLMYEMMAGQS

PFSNNNNRKMLFDAICQKPVRIPKSMDPVLADFLTRLLEKNPAKRLGS---P---GFDVFEHEFW
||.   .   ||..|... ...|...    .. .. ...|||.||||.   .     |. || | 
PFHGE-DEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 95912.m00292.AA MAST 111-255 37 1.2e-49 149.52 In-house 1-147 (337) Show / Hide 
Range on Protein: 111-255
Range on HMM: 1-147/337
Sequence Identity: 37% (55 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQSERNTLMRARHPFIIHLFNAFQT--NTHLLFVLEFAFGGDLHFQLSKNLC-SI
|. || |..|.   || ....   ...|.|.| .  .   .  .....|||.|  .  ||.  .| .|||   ..|..|.|.  |||  ..| ...  . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDC-ASLLRMYGNCM

DNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFG
.    |.|.||. |.. |||| ||. |||||.|.|.|| |||||.|||
PEWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase 95912.m00292.AA MAST 268-365 32 6e-25 72.6 In-house 229-337 (337) Show / Hide 
Range on Protein: 268-365
Range on HMM: 229-337/337
Sequence Identity: 32% (35 aa)

CGTAEYLAPEIISKSSSQTFAIDWWSFGIVAYCLYTGSVPFSNNNNRKMLFDAICQ--KPVRIPKS--------MDPVLADFLTRLLEKNPAKRLGSP-G
||| .|.|||.| . ...  ..|||| ||. | . .|..||   .  .|.|. | .  . .  |.         | |.  |   .||..|| ||||.   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

FDVFEHEFW
 .. .|.| 
DEIKQHPFF
Kinase 95912.m00292.AA TyrKc 111-364 20 2e-15 26.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 111-364
Range on HMM: 1-280/280
Sequence Identity: 20% (60 aa)

FDYIKEIGRGGNAIVYVARNRLKDELVAIKTIEKAHISTDKHREHIQSERNTLMRA--RHPFIIHLFNAFQTN-------THLLFVLEFAFGGDLHFQLS
   .|..|.|   .|| .. .   . ||.|.. . .      || . .| . ...   .|| |. |. .  .          |. |.|.. .|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KNLCSIDNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFGTARQCTSQ------CNSFCG----TAE------YLAPEIISKSSSQ
|.   . . ..  .   ||    |||| ..| |||   |.|.......| .||| .|  ..                  .        .||| | . .  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKF

TFAIDWWSFGIVAYCLYT-GSVPFSN-----NNNRKMLFDAICQKPVRIPKS--------MDPVLADFLTRLLEKNPAKRLGSPGFDVFEHEF
|.. | ||||.. . ..| |  | ..      .|. .. .    .  ..|..        . . . .  ..  . .|..|   | |    ..|
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR---PTFSEIHECF
Kinase 95912.m00292.AA Pkinase_Tyr 111-255 24 2e-09 32.58 Pfam 1-156 (270) Show / Hide 
Range on Protein: 111-255
Range on HMM: 1-156/270
Sequence Identity: 24% (38 aa)

FDYIKEIGRGGNAIVYVARNR----LKDELVAIKTIEKAHISTDKH--REHIQSERNTLMRA-RHPFIIHLFNAFQ-TNTH--LLFVLEFAFGGDLHFQL
   .|..|.|    || .. .     ..  ||.|.. |   .....  ||   .| ....   .|| |. |  .      .  .. |.|.. .|||.  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

SKN---LCSIDNFQKKLYLAEIALAVKYLHSLGIIYRDLKPENILLDSRGHIKLADFG
 |.     ...  ..  . ..|| .  ||.| ..| |||   |.|... ...| .|||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 95912.m00292.AA S_TK_X 366-423 20 0.000813 8.49 SMART 1-79 (79) Show / Hide 
Range on Protein: 366-423
Range on HMM: 1-79/79
Sequence Identity: 20% (16 aa)

DDIDWDKVYK--CEYHPTFVPLVD----EGDPGYNFE-SEDSIIEPDSLDGEETFPR--------------FDEFSYED
..|||||.|.  .|. | |.| .           ||.  ...    .. | .  ...              | .|.|  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF