Gene 95305.m00251 (T.vaginalis)

95305.m00251

Species: T.vaginalis
Alias: TvagK0343, 95305.m00251
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
95305.m00251.AA Protein None 780 None Fasta, JSON
95305.m00251.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 95305.m00251.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 95305.m00251.AA TKL 207-451 27 5.9e-86 291.86 In-house 1-364 (364) Show / Hide 
Range on Protein: 207-451
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)

IGRGVSAHVYYGKHKR--------TGEYVAIKKFTFQK-----------------------LNSAKFQSDQREVAVLATAQ--HPALLRLIG-ATDSWP-
||.| .. || ||..         ||. ||.|||  .                         . |..  ...|. ..   .  || .....| .... . 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------FCIITEWMDGGSLYKAIHTPGHMNATLRTIAAFDIARGMQFLHSRK--------IVHRDLKSLNVLLDSNKK--------------VK
            .||..|...||||.  .|        .|   | ||||||..|||..        |.|||||| |.|.|.| .              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ICDFGFSRFAEQSTEMTSN--------------------IGTPHWMAPEVLK---------------RGSRYTSKVDVYAYGVLLWELLTSETPYDGFGS
|||||.||| .||..|. .                    .||| |||||||.               .|. |. |.|||..|..|||.|| ..||.....
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

QQII---------SEVLNFDARPHLP------------EQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
 ..|         . | .   || .|            ..    |..|.. ||| ||. ||.|..|.| .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 95305.m00251.AA TKL-Unique 204-451 34 3e-79 269.57 In-house 2-290 (290) Show / Hide 
Range on Protein: 204-451
Range on HMM: 2-290/290
Sequence Identity: 34% (100 aa)

IKEIGRGVSAHVYYGKHKRTGEYVAIKKFTF-QKLNSAKFQSDQREVAVLATAQ-HPALLRLIGATD----SWP-FCIITEWMDGGSLYKAIH-------
.. ||.|... || ||..  |. ||||.| .  .... . |   .|| .. . . || .....|..     . | .||..| ..|||||. .|       
WNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--TPGH-MNATLRTIAAFDIARGMQFLHSRK--IVHRDLKSLNVLLDSN-----KKVKICDFGFSRFAEQSTEMTSN----------IGTPHWMAPEVLK
   . . .|  .|   | |||.|| .||...  | ||||||.|.|.|.|      ..||||||.|.|. ....||.|          .|.. |||||||.
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

RG-SRYTSKVDVYAYGVLLWELLTSET------PYDGFGSQQIISEVLN--FDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
.  . |. |.|||..|. |||..|..       ||.|. ..|... |       || .|.  .   ||||. ||..||  ||.||.|..  
MNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 95305.m00251.AA MLK 201-451 31 2.8e-77 263.04 In-house 1-291 (291) Show / Hide 
Range on Protein: 201-451
Range on HMM: 1-291/291
Sequence Identity: 31% (92 aa)

FEEIKEIGRGVSAHVYYGKHKRTG---EYVAIKKFTFQK----LNSAKFQSDQREVAVLATAQHPA----LLRLIGATDSW-P-FCIITEWMDGGSLYKA
... . || | .  |. |. . .      ||.|.... .      ..  .  ..|.  |.  .||       .. |.  .  . |||..|...|||||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IHT-PGHMN-----------ATLRTIA--AFDIARGMQFLHSRK---IVHRDLKSLNVLLDS------NKKVKICDFGFSRFAEQS-TEMTSNIGTPHWM
.|. ... .            ..  ..  |...||||..||| .   |.|||||| |.|.|       ....|||||| ||.  |. | |.||.||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEVL--KRGSRYTSKVDVYAYGVLLWELLTSETPYD-GFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
||||.  .|...|. |.||. .||.|||.|| |.||. .  . .|. .| .   ||..| . .  .  |.. ||. ||. ||.|. ||. .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 95305.m00251.AA Pkinase 201-451 27 1.4e-71 248.9 Pfam 1-293 (293) Show / Hide 
Range on Protein: 201-451
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQR--EVAVLATAQHPALLRLIGAT-DSWPFCIITEWMDGG----SLYKAIH--TP
.. .. ||.| .. || ..|| ||. ||.|..  .. .| | |.. |  |.....  .||  .||...  |.   ....|...||    .|.  |.    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GHM--NATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKV----KICDFGFSRF--AEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAY
| .          .  |.||....||..|.|||||. |.|.|.|  .    ||||||....     .. ||.  |||..|||||.. |. |..|||....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLWELLTSETPYDGF------GSQQIISEVLNFDARPHLPEQGN-------------------MAMRDLITLCWDRDPNTRPNFDDIVKL--F
|..|.|.|. ..|..|         .|.| ...  . . . |.  .                    ...|.|. |...||. ||....|..   |
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95305.m00251.AA LRRK 201-453 26 2.1e-71 243.56 In-house 1-351 (351) Show / Hide 
Range on Protein: 201-453
Range on HMM: 1-351/351
Sequence Identity: 26% (95 aa)

FEEIKEIGRGVSA-HVYYGKHK--------------------------RTGEYVAIKKFTF--------------------------------QKLNSAK
... ..||||...  || .| .                          . .. |||||...                                    . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FQSDQREVAVLATAQHPALLRLIGATDSWPFCIITEWMDGGSLYKAIH---TPG------HMNATLRTIAAFDIARGMQFLHSRK--IVHRDLKSLNVLL
|.. ..||... . .|| .. |.| . . |.|...| .. |.||. .|     |      |.. .|.   | .||.||..|||..  |.|||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DSNK------------KVKICDFGFSR--FAEQSTEMTSNIGTPHWMAPEVLKRG--SRYTSKVDVYAYGVLLWELLTSE-TPYDGFG----S--QQIIS
 | .            ..||.||| ||  .. ...      |.| |||||... .  . || |||.|..|..|||||| .  |.|..     .  . .|.
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

EVLNFDARPHLPEQ-GNM-----AMRDLITLCWDRDPNTRPNFDDIVKLFKQ
.  .   || .|.   .       . |||..||. ||. || | .|||  .|
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 95305.m00251.AA Dicty4 205-453 34 1.4e-66 221.06 In-house 5-277 (277) Show / Hide 
Range on Protein: 205-453
Range on HMM: 5-277/277
Sequence Identity: 34% (96 aa)

KEIGRGVSAHVYYGKHKRTGEYVAIKKF--TFQKLNSAKFQSDQREVAVLATAQHPALLRLIGATD---SWP--FCIITEWMDGGSLYKAIHT-------
..||.|  . || |. .  |  ||.||.  . |.. ..  ..  .||. ..  .|| .. . ||     | |  .|| || |  |.||. .|        
QRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQ

PGHMNATLRTI---AAFDIARGMQFLHSRK--IVHRDLKSLNVLLDSNKKVKICDFGFSR----FAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVY
   .  .|..     |||.||||. ||..   |.|||||| | | | |..||.||||.|.      .... ... .||| ||||||. .. .|..|.|||
SIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM-MHQPYNEKADVY

AYGVLLWELLTSETPYD--GFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKL--FKQ
 .| .|||.|| . ||   .    |..  | |   || .| ..    ..||. ||| ||. || |  |..      
SFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 95305.m00251.AA S_TKc 201-456 27 1.4e-65 225.05 SMART 1-231 (231) Show / Hide 
Range on Protein: 201-456
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATAQHPALLRLIGATDSWPFCIITEWMDG--GSLYKAIHTPGH-----
.| ...||.|  . || ..||.||..||||.           .. .||...|   .|| . .|... ..  .....| .||  |.|.. |.  |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-MNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTS-KVDVYAYGVLLWELL
 ..       .  |.......||..|.|||||  |.|||.   .||||||..|.       |. .|||..||||||     |.  |.|... |..|.|.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TSETPYDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVK----LFKQGLV
. ..|..    .| . ...               ..|.|  |...||. ||   .. .      .   .
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95305.m00251.AA Dicty4-Unclassified 204-451 35 5e-60 204.27 In-house 4-263 (263) Show / Hide 
Range on Protein: 204-451
Range on HMM: 4-263/263
Sequence Identity: 35% (95 aa)

IKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAK---FQSDQREVAVLATAQHPALLRLIGATDSWP------FCIITEWMDGGSLYKAIH-----
 ..||.|  . |. |  |  |  ||.|||   |  ..     |   .||..|   ||| |... |.    |      .||..| |  | |   ||     
DQFIGKGHFSKVHKGNWK--GKDVAVKKFNENK-FKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKPSE

--TPGHMNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLL
   |  .. ||    |||||.|||.||.| ..|||.|| |.|.| .  .|| ||| ||  .    ||   ||| | .||.| ..  |..| ||| |...|
QQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECL-MHESYNQKSDVYSYAMML

WELLTSETPYDGFG-SQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
.||.| . || .      .   |     || .|.     .. ||  ||  ||| || ...|..  
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 95305.m00251.AA Pkinase_Tyr 201-451 29 4.2e-56 190.62 Pfam 1-270 (270) Show / Hide 
Range on Protein: 201-451
Range on HMM: 1-270/270
Sequence Identity: 29% (79 aa)

FEEIKEIGRGVSAHVYYGKHK----RTGEYVAIKKFTFQKLNSAK--FQSDQREVAVLATA-QHPALLRLIGA-T-DSWP--FCIITEWMDGGSLYKAIH
 . .|..|.|   .|| |. |     |.  ||.|.   ..  .     ..  ||.... .  .|| ..||.|. | .. |   .|..| | .|.|..  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

T----PGHMNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFA---EQS-TEMTSNIGTPHWMAPEVLKRGSRYTSKVDVY
.    ... .       ...||.||..|.|....||||   |.|...|..||||||| .|     ..  .  ..      |||||... |  .|.| ||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVW

AYGVLLWELLT-SETP-YDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
..|||.||..|  |.| | |   ....  .     |   ||     . ||...||. ||. || | .|.  .
SFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 95305.m00251.AA TK 201-451 15 5.5e-56 185.81 In-house 1-486 (486) Show / Hide 
Range on Protein: 201-451
Range on HMM: 1-486/486
Sequence Identity: 15% (76 aa)

FEEIKEIGRGVSA---HVYYGKHKRTG-------------------------EYVAIKKFTFQKLNSAKFQSD---------------QREVAVLAT--A
 . .|..|.|       || |. .. .                         . ||.|  .    .|.. . |                .| ...     
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHPALLRLIG-ATDS------------WPFCIITEWMDGGS----LYKAIHTPGH---------------------------------------------
.|| ..||.|  |..             |..|..|.|..|.    | .  ..  .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------MNATLRTIAAFDIARGMQFLHSR------KIVHRDLKSLNVLLDSNKK-----------VKICDFG---
                               ..   .   ...||.||..|||.      ..|||||   |.|...|..           .||.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FSRFAEQSTEMTSNIGTPH---------------------------WMAPEVLKRGS--------RYTSKVDVYAYGVLLWELLT--SETPYDGF
      .|  ..... ..  .  .                           |||||.|. .         ..|.| ||...|||.||..|   |..| | 
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

GS---------QQIISEVLNF-------------DARPHLPEQGN--------------MAMRDLITLCWDRDPNTRPNFDDIVKLF
 .         |...  . .                |.  |..                 .. ||.. ||..||. ||.|..... .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 95305.m00251.AA DRK 207-453 34 1.2e-55 186.98 In-house 7-258 (258) Show / Hide 
Range on Protein: 207-453
Range on HMM: 7-258/258
Sequence Identity: 34% (89 aa)

IGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSD-QREVAVLATAQHPALLRLIGA-TDSWPFCIITEWMDGGSLYKAIHTPG-HMNATLRTIAA
||||  . |. |     |  ||.|.      |  .| .. .||. ..    ||     .|. . .   ||..| |  ||||.  | .   |   |.   .
IGRGNYGEVFRGTWR--GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMM

FDIARGMQFLHSRK--IVHRDLKSLNVLLDSNKKVKICDFGFSR----FAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLLWELLTSETPY
||.|.|| .||..   |.|||||| | | | . .||. ||| |       .. . ||  .||| | ||||| |  ||| | ||| ... |||..| . ||
FDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVL-RNQRYTEKADVYSFAIVLWECVTRQDPY

DGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLFKQ
 |    |..  |     ||  |...      |.. ||. ||  || ......    
FGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase 95305.m00251.AA Dicty5 205-455 36 3.7e-54 184.8 In-house 5-260 (260) Show / Hide 
Range on Protein: 205-455
Range on HMM: 5-260/260
Sequence Identity: 36% (94 aa)

KEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATAQ--HPALLRLIGAT---DSWPFCIITEWMDGGSLYKAIHTPGH-----M
. |  | |  || |  |  |  |||| .          .. .|||...   |  || . |  ||    |  || ..||    |||  .           .
DWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPF-HVTEYCHNGSLFNYLNDQRKTTGQPI

NATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQSTEMTSNIGTPHWMAPEVLKRGSRYTSKVDVYAYGVLLWELLTSE
   ..   | |||..|..|||  |.||||||.|.|.  | |.|| ||| ||| .   .|| ..||. |||.|. . |  |. |.|||..|. |||..|  
AYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFN-GQPYHQKCDVYSFGIVLWEMFTRK

TPYDGFGSQQIISEVLNFDARPHLPEQGNMAMRDLITLCWDRDPNTRPNFDDIVKLFKQGL
.|||   .  |   |   . || .|         ||  ||   |  || |  |.| |..  
EPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 95305.m00251.AA STE 201-446 21 4.1e-52 179.46 In-house 1-350 (359) Show / Hide 
Range on Protein: 201-446
Range on HMM: 1-350/359
Sequence Identity: 21% (77 aa)

FEEIKEIGRGVSAHVYYGKHKR---------------TGEYVAIKKFTFQKLNS---------------AKFQSDQREVAVLATAQ--HPALLRLIGAT-
.| |..||.| .  ||.....                |||..|||.  ... |.                ..|. ..|. ..   .  ||   . .|.  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

-----DSW--PFCIITEWMDGGSLYKAIH---TP-----------GHMNATLRTIAAFDIARG-MQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSR
     ...    .|. |.|||||| . |.    .           .... ..  . ...| .| ...||| .|.|||.|. |.||     ||.||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

FAEQ-----------------STEMTSNIGTPHWMAPEVLKR-GSR----YTSKVDVYAYGVLLWELLTSETPY-DGFGS---QQIISEVLNFD------
  ..                 . . .. .||| ||||||... |.     |. |.|..  | ...|..| . |. |.       .|. .   ..      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----ARPHLPEQGN-------------------MAMRDLITLCWDRDPNTRPNFDD
      | ||.                        ..| | .| ..||| ||. ..
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 95305.m00251.AA TyrKc 201-451 27 1e-49 172.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 201-451
Range on HMM: 1-280/280
Sequence Identity: 27% (79 aa)

FEEIKEIGRGVSAHVYYGKHKRTGEYVAIKKFTFQKLNSAKFQSDQREVAVLATA--QHPALLRLIG-ATDS-------WPFCIITEWMDGGSLYKAIHT
 . .|..|.|    || |. |   . ||.|.    .      .   ||  ..     .|| ..||.| .|..        | .|..| |..|.| . .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PGH-MNATLRTIAAFDIARGMQFLHSRKIVHRDLKSLNVLLDSNKKVKICDFGFSRFAEQS------TEMTSN---IGTP-----HWMAPEVLKRGSRYT
...  .       ...||.||..|||....||||   |.|...|. |||.||| ||. .        ... .     |.       |||||.. . ...|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

SKVDVYAYGVLLWELLTS-ETPYDG-----FGSQQIISEVLNFDARPHLPE-------QGNMAMRDLITLCWDRDPNTRPNFDDIVKLF
.| ||...||..||..|  ..|| |        |..|  | . . .|  |.           .| .... ||..||. ||.| .|...|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF