Gene 80651.m00178 (T.vaginalis)

80651.m00178

Species: T.vaginalis
Alias: 80651.m00178, TvagK0262
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
80651.m00178.AA Protein None 832 None Fasta, JSON
80651.m00178.kin_dom Protein Kinase Domain None 254 None Fasta, JSON

Protein domain

Protein domains of 80651.m00178.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80651.m00178.AA TKL 31-277 24 8.2e-75 254.86 In-house 1-364 (364) Show / Hide 
Range on Protein: 31-277
Range on HMM: 1-364/364
Sequence Identity: 24% (92 aa)

IGKGGFGEVIKGVDKN--------SGKIVAIKQIFSQKLEGNKL-------------------------RRYLGEIETMAKCNNFFLVPFVGFTTKPP--
||.|||||| ||. ..        .|| ||.|.. |.    . .                          .   ||  | ...   .|.|.|. . ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YSIITEYMPNGA-LNSYTRSRCKDFLSGTQLTSISIGISFGMVHLHSLN--------IIHRDLKTGNILLDENFF-------------
            . |..||.|.|  |. ..           |. .....|. || .||| |        |||||||. |||.|||.              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PRICDFGIARFDDSETS-------------------ILTKKIGTPNYMAPELITSN----------------NYTNKVDVYAFAMILYEMSENVKPFQG
 . |||||..|| . ...                    . ...|||..||||..  .                 |. |.|||.|...|.|.    .|...
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

LSVN---------DIFTGVVQKDKRPRFT------------NNTPPPLQKLIRKCWDRDPDVRPTFAQIFDEF
.  .         ..| .|..| .||               ...||.. ||. .||| ||. ||.| .| ...
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 80651.m00178.AA TKL-Unique 27-277 29 2.7e-69 236.5 In-house 1-290 (290) Show / Hide 
Range on Protein: 27-277
Range on HMM: 1-290/290
Sequence Identity: 29% (85 aa)

FQDVIGKGGFGEVIKGVDKNSGKIVAIKQIFSQKLEGNKLRR-YLGEIETMAKCN-NFFLVPFVGFTT----KPP-YSIITEYMPNGALNSYTRS-----
|  .|| ||.|.|.||. .  |..|||||.. . .  |....    |. .| | .   ..| ..|...    .|| ..|..||.| | |...        
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

---RCKDFLSGTQLTSISIGISFGMVHLHSLN--IIHRDLKTGNILLDEN-----FFPRICDFGIARFDDSE-TSILTKK--------IGTPNYMAPELI
   . .  |.  |  .. | |. || .||...  |||||||. |.|.|.|     .  .|||||...| ... ..... .        .|....||||..
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

TS--NNYTNKVDVYAFAMILYEMSENVK------PFQGLSVNDIFTGVVQ--KDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFDEF
..  . |..|.|||.|...|.|. ..        |.||.. . ..  | .  . .||   |. |. ...||..||..||. ||.| .|  . 
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 80651.m00178.AA MLK 25-277 28 1.3e-58 201.01 In-house 1-291 (291) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-291/291
Sequence Identity: 28% (82 aa)

FEFQDVIGKGGFGEVIKGVDKNSG---KIVAIKQIFSQK-------LEGNKLRRYLGEIETMAKCN-NFFLVPFVGFTTKPPYS--IITEYMPNGALNSY
..|. .||.|.||.| ||. .|     ||||.|.... .        |  ....   .   . . | .   ..|.|  ..||.   |..||...| |...
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

TRS-RCKDF-----------LSGTQLTSISIGISFGMVHLHSLN---IIHRDLKTGNILLDE------NFFPRICDFGIAR-FDDSETSILTKKIGTPNY
 .. | | .            .  .. ...  .. ||  |||.    |||||||  |||.||      .   .|||||..| . ... .  ....||. .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPELI---TSNNYTNKVDVYAFAMILYEMSENVKPFQ-GLSVNDIFTGVVQKDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFDEF
|||| |    .. |. |.||. ....|.||     |.. ...   |. .|... .||   .. |... ||. .||. ||  ||.|.||  ..
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 80651.m00178.AA S_TKc 25-278 29 1.1e-55 192.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-231/231
Sequence Identity: 29% (80 aa)

FEFQDVIGKGGFGEVIKGVDKNSGKIVAIKQIFSQKLEGNKLRRYLGEIETMAKCNNFFLVPFVGFTTKPPYSIITEYMPN--GALNSYTRSRCKDF---
.|. ..||||.||.| |...|..|.|||||.|          .. . ||. . | .  ..| . ..     . ...||...  | | .| ..| .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFFPRICDFGIARFDDSETSILTKKIGTPNYMAPELITSNNYTN-KVDVYAFAMILYEMS
 ..  .  ..   |  .. ..||..|||||||  ||||||     |||||.||.        |  .|||.|||||..    |.  |.|....  ||||| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

ENVKPFQGLSVNDIFTGVVQKDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFD--------EFS
    ||.   .. .|  ..            .|..  .||||...||. |||  ...         .. 
CGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 80651.m00178.AA Pkinase 25-277 28 1.5e-55 195.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-293/293
Sequence Identity: 28% (86 aa)

FEFQDVIGKGGFGEVIKGVDKNSGKIVAIKQIFSQKLEGNKLRRYLG--EIETMAKCNNFFLVPFVGFT-TKPPYSIITEYMPNG----ALNSYTRSRCK
...  .||.|.||.| |...|..|||||.|.|  .. . .|... .   ||. |...|  . | . ..  .|. . ...||...|     | .| . . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

DFL--SGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFFP----RICDFGIARFD-DSETSILTKKIGTPNYMAPELIT-SNNYTNKVDVYAF
  .  |  .. ..   |  |. ..|| .|||||||  |||.|.|  .    .|||||.|..      | .|   |||.|||||.|  .. |. |||....
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

AMILYEMSENVKPFQGL----SVNDIFTGVVQKDKRPRFTNNTP-----------------------PPLQKLIRKCWDRDPDVRPTFAQIFDE--F
  |||||     ||.|     . .|    .......|..  . |                       ......|..|...||  |||..||.    |
GCILYEMLCGRPPFPGHCWHDN-HDQMQ-MICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 80651.m00178.AA Dicty4 25-279 31 3.6e-53 175.76 In-house 1-277 (277) Show / Hide 
Range on Protein: 25-279
Range on HMM: 1-277/277
Sequence Identity: 31% (88 aa)

FEFQDVIGKGGFGEVIKGVDKNSGKIVAIKQI--FSQKLEGNKLRRYLGEIETMAKCNNFFLVPFVGFTT----KP-PYSIITEYMPNGALNSYTRS---
  ... ||||.|||| ||  .  ||.||.|      |... | |   . |.. |.|  .  .. | |  |    .|   .| ||||| | | |  ..   
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPS

--RCKDFLSGTQLTS---ISIGISFGMVHLHS--LNIIHRDLKTGNILLDENFFPRICDFGIAR---FDDSETSILTKKIGTPNYMAPELITSNNYTNKV
    .. |. .  ..   . . .  || .||.   .|||||||. |.| |.|.   .||||...    . . .  ..  .||| .||||   .. |. |.
EQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYAFAMILYEMSENVKPFQ--GLSVNDIFTGVVQKDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFDE--FSS
||| |...|.|.     |.|  . .   .. .|..|  ||   ...||.. .|| .||| || .||.|..|  .    .
DVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 80651.m00178.AA LRRK 84-279 31 4.8e-50 172.58 In-house 119-351 (351) Show / Hide 
Range on Protein: 84-279
Range on HMM: 119-351/351
Sequence Identity: 31% (74 aa)

LVPFVGFTTKPPYSIITEYMPNGALNSYTRSRCKDFL-----S---GTQLTSISIGISFGMVHLHSLN--IIHRDLKTGNILL---D---------ENFF
.|. .||. . |. ...||.|.|.|... ... .| .     .   ...|  |.. |. || .||| |  |||||||. ||||   .         ..  
IVSLKGFCIH-PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLK-IALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVC

PRICDFGIAR-FDDSETS-ILTKKIGTPNYMAPELITSN---NYTNKVDVYAFAMILYE-MSENVKPFQGLS-V-----NDIFTGVVQKDKRPRFTNN-T
  |.|||| | |  . .. .. .. |.| .|||| .  |   .|| |||.|.|.|||.| ..  . ||.... .     . ..   ...  || . ..  
AKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKIIEGLRPTIPQHYC

PP-----PLQKLIRKCWDRDPDVRPTFAQIFDEFSS
||      .|.|| .||. ||. ||.| ||..  |.
PPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 80651.m00178.AA Pkinase_Tyr 25-277 30 1.6e-48 165.0 Pfam 1-270 (270) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-270/270
Sequence Identity: 30% (82 aa)

FEFQDVIGKGGFGEVIKGVDK----NSGKIVAIKQIFSQKLEGNK--LRRYLGEIETMAKC-NNFFLVPFVGFTT--KPP--YSIITEYMPNGALNSYTR
 .|  ..|.| |||| ||. |    | .  ||.| .  ..       ..  . |...| .  ..  .| ..|  |  . |  . |..||||.| | .| |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

SR--CKDFLSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFFPRICDFGIAR--FDDSET-SILTKKIGTPNYMAPELITSNNYTNKVDVYA
..   |. |.  .| .... |. || .|.| |.||||| . |.|..||.. .||||| ||  ..|..     ..       |||| |  . .| | ||..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FAMILYEMSENV-KP-FQGLSVNDIFTGVVQKDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFDEF
|   ..|.     .| ..|.| ....  . ..  |     |.|... .|...||. ||. ||||..|  ..
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 80651.m00178.AA TyrKc 25-277 29 2.1e-48 168.03 SMART 1-280 (280) Show / Hide 
Range on Protein: 25-277
Range on HMM: 1-280/280
Sequence Identity: 29% (84 aa)

FEFQDVIGKGGFGEVIKGVDKNSGKIVAIKQIFSQKLEGNKLRRYLGEIETMAKC--NNFFLVPFVGFTTK--------PPYSIITEYMPNGALNSYTRS
 .. ...| | |||| ||. |     ||.| . . .     ..  . |.. | |   ..  .| ..|  |.        .|. |..||||.|.|..| |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RCKDFLSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFFPRICDFGIARFDDSE------TSILTKK--IGTP-----NYMAPELITSNNYT
. .. |.  .| |... |. || .||| |.||||| . |.|..||.  .|.||| .|. ...      ..  .||   |.        |||| |  . .|
HRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NKVDVYAFAMILYEMSEN-VKPFQG-----LSVNDIFTGVVQKDKRPRFTNN-------TPPPLQKLIRKCWDRDPDVRPTFAQIFDEF
 | ||..|   ..|.  .  .|  |     .|  ...  | | . .|.  |.        |. . .....||..||. ||||..| ..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 80651.m00178.AA STE 25-278 22 1.1e-47 164.72 In-house 1-359 (359) Show / Hide 
Range on Protein: 25-278
Range on HMM: 1-359/359
Sequence Identity: 22% (82 aa)

FEFQDVIGKGGFGEVIKGVDKN---------------SGKIVAIKQIFSQKLE---------------GNKLRRYLGEIETMAKCN--NFFLVPFVGFTT
.|....||||.||.| |.....               .|.|.||||.  .. .                ... ..| ||..| |||    . | . |   
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KPP--------YSIITEYMPNGALNSYTRSRCKDFLS------------GTQLTSISIGISFG-MVHLHSLNIIHRDLKTGNILLDENFFPRICDFGIAR
|            |. |||..| | .  ..... . .             .|.  |   |  | . .|||..|||||.| .||||       .||||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

-FDDS--------------ETS-ILTKKIGTPNYMAPELITS------NNYTNKVDVYAFAMILYEMSENVKPF---QGLSV--NDIFTGVVQK------
 ..||               ..   .  .||| .|||| |.       . |. |.|.. .   . || .   |.   . ...  . .| ...|       
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DKRPRFTNNTP-------------------PPLQKLIRKCWDRDPDVRPTFAQIFD---EFS
   .. |.. ...                    |...  |.|| ..||. |||  |      .| 
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 80651.m00178.AA Dicty5 98-281 37 9.5e-47 158.93 In-house 76-260 (260) Show / Hide 
Range on Protein: 98-281
Range on HMM: 76-260/260
Sequence Identity: 37% (71 aa)

IITEYMPNGALNSYTRSRCK----DFLSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFFPRICDFGIARFDDSETSILTKKIGTPNYMAPE
..|||  || | .| . . |      . ..|| .. |.|  .| |||| ||||||||  |.|. ||.   | |||. || |      |  .||...||.|
HVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQL-HMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYH-MTMHVGTQCWMACE

LITSNNYTNKVDVYAFAMILYEMSENVKPFQGLSVNDIFTGVVQKDKRPRFTNNTPPPLQKLIRKCWDRDPDVRPTFAQIFDEFSSGR
| ... |..|.|||.|. .|.||     |.  .   .|    |.|  ||      |    .|| |||   |  ||.|  | . | |  
LFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIPV-MVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 80651.m00178.AA RIPK 31-277 28 5.6e-46 154.66 In-house 1-290 (290) Show / Hide 
Range on Protein: 31-277
Range on HMM: 1-290/290
Sequence Identity: 28% (83 aa)

IGKGGFGEVIKGVDKNSGKIVAIKQIFSQK----LEGNKLRRYLGEIETMAKCNNFFLVPFVGFTTKP------P-YSIITEYMPNGALNSYTRSRCK--
.|.|||||| | . .  |  ||.|   . .    ..  .    . | . |.|  . . ||  ||. ..        |.| .|||.|| |.    ....  
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

---DFLSGTQLTS-ISIGISFGMVHLHSLN--IIHRDLKTGNILLDENFFPRICDFGIARFDDSETSILTK--------KI-------GTPNYMAPELIT
   | ..   |.  .   || ||  ||| |  |||||||..|||.| ||   | ||| | .   ..| ...        ..       ||  ||.||.. 
HHPDPWP---LRCRMIHEISCGMCYLHSMNPPIIHRDLKPENILVDNNFHVKIADFGLATWM--MWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFR

--SNNY----TNKVDVYAFAMILYEMSENVKPFQGLSVNDIFTGVVQKDKRPRFT---NNTPPP-----LQKLIRKCWDRDPDVRPTFAQIFDEF
    .     | | ||| ||....|   . .|. .     ..  ......||  .    ..| |     . .|...||. ||..||.|  . ...
TDNKKPIKVVTPKYDVYSFAIVMWEVLTQKHPYEDRKCMMMIMMCCKQGHRPCLQPVPEYWPEPPHCEQMIELMQRCWQQDPNDRPCFQECEEWT
Kinase 80651.m00178.AA ULK 25-275 25 2.3e-44 153.7 In-house 1-320 (324) Show / Hide 
Range on Protein: 25-275
Range on HMM: 1-320/324
Sequence Identity: 25% (81 aa)

FEFQDVIGKGGFG-EVIKGVDKNS---GKIVAIKQIFSQKLEGNKLR--------RYLGEIETMAKCN------NFFLVPFVG-FTTKPP--YSIITEYM
..  ...||| ||  | || .|..   ...||.|.|  .|.  .|..            ||..| | .      .   | .   | |.    . ||.|| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYC

PNGALNSYTRSR-------CKDFLSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFF------------PRICDFGIARF-DD--SETSILT
. | | .|   .        | .||  .  .. . |  |. .||. ||||||.|  |||. ...               |.||| |.. |.   |  ...
NGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

KKI------GTPNYMAPELITSN----NYTNK-VDVYAFAMILYEMSENVKPFQGLSVNDIF------------------TGVVQKDKRPRFTNNTPPPL
         ||| ||||... ..    .|... .|.. . .|.|||  .  ||..   || .                  .  .|..| |   ..  | .
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPP-KDPKISPEC

QKLIRKCWDRDPDVRPTFAQIFD
. |||..  .|.. | .. .||.
KDLIRRMLQYDEKDRISWEEIFN
Kinase 80651.m00178.AA ULK 25-275 24 2.6e-44 152.59 In-house 1-325 (329) Show / Hide 
Range on Protein: 25-275
Range on HMM: 1-325/329
Sequence Identity: 24% (81 aa)

FEFQDVIGKGGFGEVIKGVDKNS----GKIVAIKQIFSQKLEGNKLRRY-------LG-EIETMAKCN--------NFFLVPFVG-FTTKPP--YSIITE
..  ...||| || | || .|..    ...||.|.| .||.  ..  ..       |  ||..| | .        .   | .   | |.    . ||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YMPNGALNSYTRSR--------CKDFLSGTQLTSISIGISFGMVHLHSLNIIHRDLKTGNILLDENFF------------PRICDFGIARF-DDS--ETS
| . | | .|   .         | .||  .  .. . |  |. .||. ||||||.|  |||.....               |.||| |.. |..  |  
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ILTKKI------GTPNYMAPELITSN----NYTNK-VDVYAFAMILYEMSENVKPFQGLSVNDIFTGVVQKDKR-------------PRFT-----NNTP
...         ||| ||||... ..    .|... .|.. . .|.|||  .  ||..   || .   .|| ..             ..|      ..  
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PPLQKLIRKCWDRDPDVRPTFAQIFD
| .. |||..  .|.. | .. ..|.
PECKDLIRRMLQYDEKDRISWEELFN
Kinase 80651.m00178.AA LRRK 25-56 18 0.002081 7.9 In-house 1-59 (351) Show / Hide 
Range on Protein: 25-56
Range on HMM: 1-59/351
Sequence Identity: 18% (11 aa)

FEFQDVIGKGGFG-EVIKGVDKN--------------------------SGKIVAIKQI
....  ||.|||| .| ..  ..                          ... ||||..
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKW
Kinase 80651.m00178.AA Dicty5 26-54 44 0.196381 0.69 In-house 2-28 (260) Show / Hide 
Range on Protein: 26-54
Range on HMM: 2-28/260
Sequence Identity: 44% (13 aa)

EFQDVIGKGGFGEVIKGVDKNSGKIVAIK
 | |.|  |  | | .|. |  |. ||||
SFHDWIASGASGRVYNGIYK--GMDVAIK