Gene 93316.m00032 (T.vaginalis)

93316.m00032

Species: T.vaginalis
Alias: 93316.m00032, TvagK0327
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93316.m00032.AA Protein None 788 None Fasta, JSON
93316.m00032.kin_dom Protein Kinase Domain None 256 None Fasta, JSON

Protein domain

Protein domains of 93316.m00032.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93316.m00032.AA TKL 210-459 26 1.4e-86 293.94 In-house 1-364 (364) Show / Hide 
Range on Protein: 210-459
Range on HMM: 1-364/364
Sequence Identity: 26% (97 aa)

IGHGLSAVVYKGTYKK--------TGEKVALKRFKFVNLNGSNL----------------------QLFQREVAVLAVLNKISHPCLIRFIG-ATDVPP-
|| | ...||||...         ||. || |.||  | . ...                      .....|. .. ......|| ...|.| ... |. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YTIITEFMPNKSLFDDCRKNHKMSATQYTIAAYDIARGMQYLHACQ--------IVHRDLKSLNILLDNNYK--------------IR
            . |..|..|. ||...          |    |.||||||.|||...        |.|||||| |||.|.|..              . 
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

ICDFGFAKSF----NDDDTFKAQT---------------VGTTQWMAPEILV----SSH-----------KFTSKIDVYAYGILLVELLTKKRPY--PGM
|||||.....    |. || ...                .||..|||||.|      ..           ... |.|||..||.| |.|| .|||  ...
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

DDKK------ELAHKIVEEGLRPKLK------------KNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
.. .      | . .....|||| ..            ...|| .|.|...|||..|. ||.|.||..|.
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93316.m00032.AA TKL-Unique 206-459 35 2.5e-76 259.9 In-house 1-290 (290) Show / Hide 
Range on Protein: 206-459
Range on HMM: 1-290/290
Sequence Identity: 35% (106 aa)

IEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGSNL--QLFQREVAVLAVLNKISHPCLIRFIGATD----VPP-YTIITEFMPNKSLFDDCR---
. . || | ...||||...  |..||.|.|.. |   ||   | | .|| .. .|.   || . ...|..      || . |..|..|  || |      
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHY--HPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN

-------KNHKMSATQYTIAAYDIARGMQYLHACQ--IVHRDLKSLNILLDNN-----YKIRICDFGFAKSFN-DDDTFKA--------QTVGTTQWMAP
       .|.|..  |.   | |||.|| ||| |.  | ||||||.|.|.|||     ..|.|||||..|. . ......           .|...||||
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EILVSS-HKFTSKIDVYAYGILLVELLTKKR------PYPGMDDK--KELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
|.| ..  ... |.|||..|| | |..| |.      || |||..  .|..|.  ||..||..  . |. ..|||.|||. .|. ||.||||. | 
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYM-EENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 93316.m00032.AA MLK 204-459 30 1.7e-72 247.12 In-house 1-291 (291) Show / Hide 
Range on Protein: 204-459
Range on HMM: 1-291/291
Sequence Identity: 30% (88 aa)

FEIEEEIGHGLSAVVYKGTYKKTG---EKVALKRFKF----VNLNGSNLQLFQREVAVLAVLNKIS-HPCLIRFIGA-TDVPP-YTIITEFMPNKSLFDD
....| ||.| . .|.||.....      ||.||...    .   ..  . |..|.  |..|..   ||| |.| |. .. |. . |..|.... ||.. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

CRKNHK--------------MSATQYTIAAYDIARGMQYLHACQ---IVHRDLKSLNILLDN------NYKIRICDFGFAKSFNDDDTFKAQTVGTTQWM
.. . .              ..  .    |...||||.|||. .   |.|||||| |||.|.      . . .||||| ...... .| .  . ||  ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APEIL--VSSHKFTSKIDVYAYGILLVELLTKKRPYPGMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
|||..    . |.. | ||. .|..| |.||.. || ...|  . | .....|||| . .. |. .| |..|||...|  ||.|..||| .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 93316.m00032.AA Dicty4 204-461 34 1.1e-71 238.36 In-house 1-277 (277) Show / Hide 
Range on Protein: 204-461
Range on HMM: 1-277/277
Sequence Identity: 34% (97 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRF--KFVNLNGSNLQLFQREVAVLAVLNKISHPCLIRFIGATD----VP-PYTIITEFMPNKSLFDDCRK
  ||..|| |  . ||||| .  | .|| | .  . .|.  . |. | .||. ..   ||.|| .. | ||       |    | ||.||  .|.   ..
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMC---KIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD

-------NHKMSATQYTI---AAYDIARGMQYLHA--CQIVHRDLKSLNILLDNNYKIRICDFGFAKSFNDDDTFKA---QTVGTTQWMAPEILVSSHKF
       . |.. . ..     | |.||||..||.  . |.|||||| |.| | |... .||||... .  . ..|.    ..||. |||||... .. .
KPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMM-HQPY

TSKIDVYAYGILLVELLTKKRPYP-GMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQR--FEN
..| ||| .||.| |.||.. ||.   ..  ...  .....|||.. ...|| .|.||. ||| .| .||.| ||.||   | 
NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 93316.m00032.AA S_TKc 204-466 28 1.2e-66 228.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 204-466
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGSNLQLFQREVAVLAVLNKISHPCLIRFIGATDVPPYTIITEFMPN--KSLFDDCRKNHK--
.|| ..||.|  ..|||.. ||||..||.|. |         . ..||...|       || ....... .   . ...|....   .|||  .|. .  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK----HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHG

----MSATQYTIAAYDIARGMQYLHACQIVHRDLKSLNILLDNNYKIRICDFGFAKSFNDDDTFKAQTVGTTQWMAPEILVSSHKFTS-KIDVYAYGILL
    ..  .    .| |.....|.|  .|.|||||  |||||.   | |||||.|. .          .||  .||||.|    ...  |.|... |..|
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCIL

VELLTKKRPYPGMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF--ENLEIYF
 |.|. . |.|   . ... .||.            .| .||.| .|.. .|. |||  |. |.    ..  .|
YEMLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93316.m00032.AA LRRK 204-461 25 6e-64 218.77 In-house 1-351 (351) Show / Hide 
Range on Protein: 204-461
Range on HMM: 1-351/351
Sequence Identity: 25% (90 aa)

FEIEEEIGHGLSA-VVYKGTYKK--------------------------TGEKVALKRFKFV---------NLNG-----------------------SN
..|||.|| | .. .||......                           ...|| | ...          | |.                        .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LQLFQREVAVLAVLNKISHPCLIRFIGATDVPPYTIITEFMPNKSLFDDCRKNHKM-------S---ATQYTIAAYDIARGMQYLHACQ--IVHRDLKSL
...|..||...  ||   ||...  .| .   |.....|..|. .| . .......       .    ... | |..||.||.||| .   |.|||||| 
FREFRHEVWIMSHLN---HPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKI-ALQIAKGMEYLHSHNPPIIHRDLKSP

NILL---D---------NNYKIRICDFGFAK-SFNDDDTFKAQTVGTTQWMAPEILVSS--HKFTSKIDVYAYGILLVELLTKK-RPYPGMD--DKKELA
||||   .         ..... |.|||     . .  ..    ||. .||||||.       .| |.|.|..|..| |||| . .|. ..|  |. .. 
NILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWM

HKIVE---EGLRPKLKKN-TPP-----LLKDLITQCWDANPDVRPTFDEIVQRFEN
 .| .   |||||... .  ||      ..|||..||...|. ||.| .||.| . 
EQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 93316.m00032.AA Pkinase 204-459 28 2.1e-63 221.75 Pfam 1-293 (293) Show / Hide 
Range on Protein: 204-459
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGSNLQLFQR--EVAVLAVLNKISHPCLIRFIGATDVPPYTI-ITEFMPNK----SLFDDCR-
..|.. || | ...|||.. |.||..||.|..| .. . . .|   |  |..... ||   ||. .|....   ...   ..|....     .|||  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST

-KNHKM--SATQYTIAAYDIARGMQYLHACQIVHRDLKSLNILLDNNYKI----RICDFGFAKSF-NDDDTFKAQTVGTTQWMAPEILVSSHKFTSKIDV
 .. ..  |  .    .| |.||..|.|.. |.|||||. |||.|||. |    .|||||.|| | .  ..     .||  .||||.. .. . ..|.|.
WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YAYGILLVELLTKKRPYPGM--DDKKELAHKIVEEGLRPKLKKNTP-----------------------PLLKDLITQCWDANPDVRPTFDEIVQR--F
...|..| |.|... |.||   .|.     ..... ..|.|. . |                       . .||.|. |.. .|  |||...|.|   |
WSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93316.m00032.AA TK 204-459 17 1.9e-62 207.84 In-house 1-486 (486) Show / Hide 
Range on Protein: 204-459
Range on HMM: 1-486/486
Sequence Identity: 17% (84 aa)

FEIEEEIGHGLSA---VVYKGTYKKTG-------------------------EKVALKRFKFVNLNGSNLQL------------FQREVAVLAVLN--KI
 ......|.|      .||||...  .                         ..|| |  |  . . .. ..            | .|........  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPCLIRFIG-ATDV------------PPYTIITEFMPNKS----LFDDCRKNHK---------------------------------------------
 || ..|..|  |..            .|. |..|.||. .    | |  ||...                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------MSATQYTIAAYDIARGMQYLHAC------QIVHRDLKSLNILLDNNYK-----------IRICDFG---
                               ..  |    ...||.||.|||..      ..|||||   |.|...|..           ..|.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----FAKSF-NDDDTFKAQTVGTTQ-------------------------WMAPEILVSSH--------KFTSKIDVYAYGILLVELLT--KKRPYPGM
      |.   .|||  .... ||.                          ||||| | . .        |||.| ||...|.|. |..|  .. .|.||
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DD--------KKELAHKIVEE-------------GLRPKLKKNTP--------------PLLKDLITQCWDANPDVRPTFDEIVQRF
..         .|.  .....             ..|..  .. |              ... ||..|||...|. ||||.......
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 93316.m00032.AA Dicty4-Unclassified 204-459 32 1.8e-60 205.77 In-house 1-263 (263) Show / Hide 
Range on Protein: 204-459
Range on HMM: 1-263/263
Sequence Identity: 32% (89 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGS--NLQLFQREVAVLAVLNKISHPCLIRFIGATDVP-----PYTIITEFMPNKSLFDDCR-
  |  .|| |  . |.||  |  |  || | |           .| | .||..|     |.|| |..  |.   |      . |..|||.   ||     
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGS---IQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHS

----KNHKMSATQ--YTIAAYDIARGMQYLHACQIVHRDLKSLNILLDNNYKIRICDFGFAKSFNDDDTFKAQTVG-TTQWMAPEILVSSHKFTSKIDVY
    ..  ..         | |||.|||.||   ..|||.|| |||.| .. |.| ||| .     | .|   |.. |  | .||.|     ...| |||
KPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLM-HESYNQKSDVY

AYGILLVELLTKKRPYPGMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
 |...| ||.|   || .     ..|  . . .||||.  | .. .| ||  ||   |  |||...|.|. 
SYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 93316.m00032.AA TyrKc 204-459 28 4.3e-52 180.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 204-459
Range on HMM: 1-280/280
Sequence Identity: 28% (83 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGSNLQLFQREVAVLAVLNKI--SHPCLIRFIG-ATDV-------PPYTIITEFMPNKSLFDD
 . ....|.|   .|||||.|   ..|| |  |        .. | ||  ..    |.  .||...|..| .|.        .|. |..|.||. .| .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMC---KLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL-KD

CRKNHK--MSATQYTIAAYDIARGMQYLHACQIVHRDLKSLNILLDNNYKIRICDFGFAKSFNDD-------DTFKA----QTV--GTTQWMAPEILVSS
  ..|.   .  .    ...||.||.|||  ...||||   |.|...|. ..|.||| ..   ||       |. ..    ..       ||||| .   
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NY

HKFTSKIDVYAYGILLVELLTK-KRPYPGM----DDKKELAHKIVEEGLRPKLKKN-------TPPLLKDLITQCWDANPDVRPTFDEIVQRF
.|||.| ||...|... |..|  . |||||     . .|. ... . . .|. . .        |. . ....|||...|. |||| ||...|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93316.m00032.AA STE 204-454 21 2.2e-51 177.03 In-house 1-350 (359) Show / Hide 
Range on Protein: 204-454
Range on HMM: 1-350/359
Sequence Identity: 21% (77 aa)

FEIEEEIGHGLSAVVYKGTYKK---------------TGEKVALKRFKFVNLN---------------GSNLQLFQREVAVLAVLNKISHPCLIRFIGAT
.|. |.||.| . .|||. ..|               ||| .| |. .. | |                ...| ...|. ..  .|.. ||  ....|. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGCY

DVPP--------YTIITEFMPNKSLFDDCRKN--------------HKMSATQYTIAAYDIARG-MQYLHACQIVHRDLKSLNILLDNNYKIRICDFGFA
 .            |. |.|.. || |  ...              |... .|  . ...| .| ..|||  .|.|||.|. ||||     . .||||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

KSFNDD----------------DTFKAQTVGTTQWMAPEILVS-----SHKFTSKIDVYAYGILLVELLTKKRPYPGMDDKKELAHKI----VEE-----
....|.                .      |||  |||||..       ... . | |..  |....|..| | |.  | . . . ...    ...     
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

----GLRPKLKKNTP-------------------PLLKDLITQCWDANPDVRPTFDE
    |  |.|. ..                    | .|| | .| . .|. ||| ..
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 93316.m00032.AA TKL-ciliate2 204-460 32 7.7e-50 164.27 In-house 1-273 (273) Show / Hide 
Range on Protein: 204-460
Range on HMM: 1-273/273
Sequence Identity: 32% (91 aa)

FEIEEEIGHGLSAVVYKGTYKKTGEKVALKRFKFVNLNGSNLQLFQREVAVLAVLNKISHPCLIRFIGA-TDVPPYTIITEFMPNKSLFDDCRK-NHKMS
 ||.. |  |   ..||  .. .   || |.|| .  |   .. |  |   .  |    || .. |.|| |..| ..|| |.    ||.      . ...
LEIQNKITEGGYGIIYKAKWREI--VVAVKKFKMDHDNQQQIRDFVNECHAMEALR---HPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQNQDVRLT

ATQYTIAAYDIARGMQYLHACQ--IVHRDLK--------------------SLNILLDNNYKIRICDFGFAKSFNDDDTFKAQTVGTTQWMAPEILVSSH
       | |||||. |||. .  |.|||||                    |||.|.| |.. .. |||. .    .| .    .|| ||||||. ... 
WEDRRRIALDIARGVHYLHSSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTR-VKPQDNYMTNKIGTYQWMAPEV-IKAF

KFTSKIDVYAYGILLVELLTKKRPYPGMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRFE
 .| | ||..|.|.| |.  .  || ..      | |.. . ||| . || || . ||. .||| | ..||.|.||.. .|
YYTEKADVFSYSIILWEIASREPPYRNKKGDV-VAEKVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase 93316.m00032.AA LISK 309-459 30 1.8e-44 142.25 In-house 107-296 (296) Show / Hide 
Range on Protein: 309-459
Range on HMM: 107-296/296
Sequence Identity: 30% (61 aa)

AYDIARGMQYLHACQIVHRDLKSLNILLDNN----YKIRICDFGFAKSFNDDD--------------------------------TFK--AQTVGTTQWM
|.|||.|| |||. .|.|||||| |.|...|    ..|..||||||. .....                                . |     .||. ||
ALDIACGMSYLHSMNIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRMTICGTPYWM

APEILVSSHKFTSKIDVYAYGILLVELLTKKRPYP-----GM--D---DKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
|||.|. . . . . ||. .||.|.|. | ... |      .  |   | .|. .||...        . || . ||   | . .|. ||.|.||||..
APEMLLGQ-SYDESCDVFSFGIVLCEIITRVKADPDYWPRTPQHDFGLDYEEFWQKICPD--------DCPPPFLDLCFDCCKYDPKNRPSFKEIVQWL
Kinase 93316.m00032.AA Pkinase_Tyr 309-459 38 5.1e-40 136.17 Pfam 117-270 (270) Show / Hide 
Range on Protein: 309-459
Range on HMM: 117-270/270
Sequence Identity: 38% (60 aa)

AYDIARGMQYLHACQIVHRDLKSLNILLDNNYKIRICDFGFAKSF-NDDDT--FKAQTVGTTQWMAPEILVSSHKFTSKIDVYAYGILLVELLT-KKRP-
...||.||.||.. ...||||   |.|...| ...||||| |.   |||     .  .     ||||| .  .  ||.| ||...|.|. |..|  . | 
CWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQPT

YPGMDDKKELAHKIVEEGLRPKLKKNTPPLLKDLITQCWDANPDVRPTFDEIVQRF
|||| .  |. ..| |.| | .  .|.|. . ||..|||...|. |||| ||....
YPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 93316.m00032.AA LISK 209-272 30 2.8e-12 36.0 In-house 1-64 (296) Show / Hide 
Range on Protein: 209-272
Range on HMM: 1-64/296
Sequence Identity: 30% (21 aa)

EIGHGLSAVVYKGTYKKTGEKVALKRFKF----VNLNGSNLQLFQREVAVLAVLNKISHPCLIRFIGA
||| |  . |||||.. ||. .|.|  .     .|.. ...  ..|||   .......||  ..|.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDP-EYQKFMLREV---QMMKNLRHPNIVQFMGV
Kinase 93316.m00032.AA Pkinase_Tyr 204-287 27 1.9e-08 29.24 Pfam 1-91 (270) Show / Hide 
Range on Protein: 204-287
Range on HMM: 1-91/270
Sequence Identity: 27% (26 aa)

FEIEEEIGHGLSAVVYKGTYK----KTGEKVALKRFKFVNLNGSN--LQLFQREVAVLAVLNKI-SHPCLIRFIGA-T-DVPP--YTIITEFMPN
 .. ...|.|   .|||||.|    .|. .|| |  |  .   ..  .. | ||....    .. .|| ..|..|. | .  |  . |..|.||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMK---QLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH