Gene 84394.m00075 (T.vaginalis)

84394.m00075

Species: T.vaginalis
Alias: 84394.m00075, TvagK0037
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag3

Sequence

Name Sequence Type Origin Length Description Download
84394.m00075.AA Protein None 409 None Fasta, JSON
84394.m00075.kin_dom Protein Kinase Domain None 250 None Fasta, JSON

Protein domain

Protein domains of 84394.m00075.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 84394.m00075.AA S_TKc 23-272 31 1e-86 295.35 SMART 1-231 (231) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQHEFNGIMREISVFMQVEHPNVCSCYRMSLEGKSLILFIEYAVG--GTLLSYVNKNSG----
.|||..|| |||..|. .||. || . | ||..         . |.|||.. ..  |||.. .| .  . ..| .. ||. |  |.|..|  |. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNVKITDFGLASTSYCNIMRSYVGTPGYTPPEVIAGNDYDE-KCDVWSLGVCLYAMI
  . | .|.... || .|| |.|.    .||||| ||||.|   ..||.|||||        ....||| | .|||.    |.  |||.||.|..|| |.
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TANLPFSTGNNYRKLIDEAENLRFPLNFSPALVDLLKRMLHVRPSSRCRLIDIQN-------HPWL
.   ||.   .. ....           || . |.....|.. |. |    .. .       |||.
CGYPPFP---QMQMMFKKIG--------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84394.m00075.AA CAMK 28-272 22 3.4e-82 264.52 In-house 1-425 (425) Show / Hide 
Range on Protein: 28-272
Range on HMM: 1-425/425
Sequence Identity: 22% (94 aa)

EIGAGAFSTVHIARHI-TTG-----------VYAAAKIVDLSRLG--------------------------QHEFNGIMREISVFMQ-------VEHPNV
..| |.|..|. ..|. |||           .  |.||.| ..|                           ..    ..|||.. ..       . |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

CSCYRMSL------------EGKS--------LILFI---EYAVGG----TLLSYVNKNSG---------------LKEPEAQRIFFQIYSALRYLHNYY
...| .                .         ....    ||. ||     |..|. ....               ..| ||.|.| || ||..|.|.  
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FLVHRDLKLENILFDAN-----------------WNVKITDFGLA--STSYCN-----------------------IMRSYVGTPGYTP-PEVIAGND--
  ||||||.||||.| |                 .|.||.|||.|   ..  |                        |. ..|||.| . |||. |.   
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------------YDEKCDVWSLGVCLYAMITANLPFS------------TGNNYRKLIDEAENLRFPLN--------------------------FSPAL
            |..|||.||.|| ||.| .  .||             .|.|...|     . ..                             .|.  
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

VDLLKRMLHVRPSSRCRLIDIQNHPWL
 ||...|| | |. |  . .. ||||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 84394.m00075.AA CAMKL 23-272 31 2.1e-79 253.05 In-house 1-297 (297) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-297/297
Sequence Identity: 31% (95 aa)

FEILEEIGAGAFSTVHIARH-ITTGVYAAAKIVDLSRLGQHEFNG-------------IMREISVFMQVE---HPNVCSCYRMSLEGKS------LILFI
..|....| |.|..|  |.| .|||.  | ||.| ...   ...              | |||.  ...    |||... | .    .       . |. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYAVGGT--LLSYVNKNSG----LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANW--NVKITDFGLASTSY-C----NI-MRSYVGTPGY
||. ||   |. |. |. .    ..|.||.|.| || ||. |.|.    ||||.|.||||.| |   |.||.|||..     |    .  ..   |.| |
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPY

TPPEVIAG--NDYD-EKCDVWSLGVCLYAMITANLPFSTGNN----------YRKLIDEAENLRFPLNFSPALVDLLKRMLHVRPSSRCRLIDIQNHPWL
 .||...|   .||  | |.||.|| ||||.. .|||   ..          |.| .   .. . ..  |  . ||...|| | |. |  . .| ||||.
MAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 84394.m00075.AA AGC 23-272 21 4.2e-78 200.69 In-house 1-395 (395) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-395/395
Sequence Identity: 21% (85 aa)

FEILEEIGAGAFSTVHIARHI------TTGVYAAAKIVD----LSRLGQHEFNGIMRE------------ISVFMQVE----------HPNVCS-CYRMS
||.|  || |.|..|. .|.       .|| | | |...      .. ...   .|.|              .....           ||....  .   
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

LEGKS--LILFIEYAV---------GG-TLLSYVN---KNSGLKEPEAQRIFFQ-------IYSALRYLHNYYFLVHRD-LKLENILFDANWNVKITDFG
   .   | .  ||.          ||  |...     |.  . |..|. .. .       | .|| |||.    .||| ||.||||.|.. ..|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAST--SYC--------------------------------------------------NIMRSYVG--TPGYTPPEVIAGNDYDEKCDVWS--LGVCLY
|.    ...                                                  .   . .|  || | .||..    |.  || ||  ||...|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

AMITANLPFSTGN---------NYRKLIDEAE--------NLRFP----------LNFSPALVDLLKRMLHVRPSSRCR----------LIDIQNHPWL
 |.|   ||.  |         |  .. .  .        ...||           .||| ..||.|..|.. |. |              .|.|||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 84394.m00075.AA Pkinase 23-272 28 9.5e-70 242.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQHEFNGIMR--EISVFMQVEHPNVCSCYRMSLEGKSLILFIEYAVGG----TLLSYVN--KN
..|.. ||.|.|..| ...|. ||   | ||.....    .     |  ||..   . |||.. .|..  ..... .  ||. ||     | .|.   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

SGL--KEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNV----KITDFGLA----STSYCNIMRSYVGTPGYTPPEVIA-GNDYDEKCDVW
 ..   | |..... || ..| |.|.    .|||||.||||.| | ..    ||.|||||      ..   | ...|||.| .||||  |..|. |.|.|
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGVCLYAMITANLPFSTG----NNYRKLIDEAENLRFPLNFS-------------------------PALVDLLKRMLHVRPSSRCRLIDIQNHPWL
|.|. || |.. ..||.      | ....   ..... || |.                         ... |..|..|.. |..|.   .| .|||.
SCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84394.m00075.AA Ciliate-E2 23-272 23 1.7e-69 237.22 In-house 1-365 (365) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-365/365
Sequence Identity: 23% (87 aa)

FEILEEIGAGAFSTVHIARHITTGV------------------YAAAKIVDLSRLGQHEFNGIMREISVFMQVE----------------HPNVCSCYRM
..... || |.|..|  .... ..                   ....||. . .. . . . |..||.......                |||.. .|  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

SL--EGKSLILFIEYAVGGTLLSYVNKN-----------SGLKEPEAQRIFFQIYS---------------ALRYLHNYYFLVHRDLKLENILFDANWNV
      ... |  ||. ||.|..| ..|             ..| |...|. || .               ||.|||.    .|||.|.|||||     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGLAS---------------------------TSYC------NIMRSYVGTPGYTPPEVIAGND---------YDEKCDVWSLGVCLYAMITANLP
||.||||.                            ..|       |. ....||||| .||.. | .         ||.|||.|||||.|| |.. ..|
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FSTGNNYRKLIDEAENLRFP------------------LNFSPALVDLLKR----MLHVRPSSRCR-LIDIQNHPWL
|         . .  ...||                  .. |.   ||.|.    || . |. |     .| ||||.
F-------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 84394.m00075.AA AMPK 23-272 37 1.2e-66 196.94 In-house 1-254 (254) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-254/254
Sequence Identity: 37% (96 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQHEFNG-IMREISVFMQVEHPNVCSCYRMS-LEGKSLILFIEYAVGGTLLSYVNKNSGLKEP
. | . || |.|  | .. ||.|| . | || .  .. . .  . | |||.    . ||..   |.      . .....||. || | .|. |.  |.| 
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGRLQER

EAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNVKITDFGLAST-SYCNIMRSYVGTPGYTPPEVIAGNDYD-EKCDVWSLGVCLYAMITANLP
||.| | || |.. |.|.    ||||||.||.|.|.| |.|| ||||  . .  .  .   | | |  ||.|.|  |   . |.|| || ||||. . ||
EACRFFQQIISGVEYCHRHM-IVHRDLKPENLLLDHNKNIKIVDFGLSNMMKDGEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLP

F---STGNNYRKLIDEAENLRFPLNFSPALVDLLKRMLHVRPSSRCRLIDIQNHPWL
|   .| . |.| .  .     | ..||   ||.|.|| | |  |    || ||||.
FDDENTPTLYKKIK--NGEYYIPKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase 84394.m00075.AA QIK 23-272 32 3.9e-61 209.41 In-house 1-272 (272) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-272/272
Sequence Identity: 32% (89 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQHEFNGIMREISVFMQVEHPNVCSCYRMSLEGKSLI-LFIEYAVGGTLLSYVNKNSG-----
..|   || | | .| .|||. |    | ||.| |.| . ... . ||. .  . .||..   |   .| .. . .  ||. .| .  |..|.       
YDIERTIGKGNFAVVKLARHRITKTKVAIKIIDKSQLDEENLQKCYREVQIMKMLYHPHIIKLYQV-METDDMMYIVTEYCSNGEMFDYLCKHGRKGVKM

---------------LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNVKITDFGLASTSYCNI-MRSYVGTPGYTPPEVIAGNDYD-EK
               ..|.||.|.| || ||  |.|.    |||||| ||||.|.| |.|| |||.   ..    . ...|.| |  ||.  |..||  |
VNSPDIGDQVLMGVPMAENEARRWFWQICSAVHYCHKRN-IVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQLLMTWCGSPPYAAPEMFEGKEYDGPK

CDVWSLGVCLYAMITANLPFSTGNNYRKLIDE--AENLRFPLNFSPALVDLLKRMLHVRPSSRCRLIDIQNHPWL
 |.||.|| ||....  |||  | .  .| .       | |   |  . .| ..|| | |. |     | .|.|.
VDIWSMGVVLYVLVCGALPF-DGKTLQNLRQRVLSGKFRIPFFMSQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 84394.m00075.AA ULK 23-272 25 7.9e-61 208.4 In-house 1-329 (329) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-329/329
Sequence Identity: 25% (85 aa)

FEILEEIGAGAFSTVHIARHITT----GVYAAAKIVDLS--RLGQHE------FNGIMREISVFMQVE--------HPNVCSCYRMSLEG--KSLILFIE
... ...| |.| .|. .|.. |    ... |.|..|..  .  ..|       . ...|| .  .          |||..  | .. .   . . .. |
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YAVGGTLLSYVNKNSG----------LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDA-NWN-----------VKITDFGLASTSYCN----
|  ||.| .| .|| .          | |.||. .| || .....||     .|||.|..||| .  ..            .||.|||.| .  ..    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNI-IHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQ

-IMRSYV------GTPGYTPPEVIAGN----DYD-EKCDVWSLGVCLYAMITANLPFSTG-NNYR-----KLIDE---------AENLRFPLN-----FS
 .| ..|      ||| |  |... |.    .|.  |||.||||. .| |..   ||..  | .      |||.           ..|.|| .     .|
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

PALVDLLKRMLHVRPSSRCRLIDIQNHPWL
| . ||..||| . .. |.   .. ||||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 84394.m00075.AA ULK 23-272 26 1.6e-60 207.41 In-house 1-324 (324) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-324/324
Sequence Identity: 26% (85 aa)

FEILEEIGAGAFS-TVHIARHITT---GVYAAAKIVDLSRLGQ--HE------FNGIMREISVFMQVE---HPN--VCSCYRMSLEG--KSLILFIEYAV
... ...| |.|  .|. .|.. |   ..| |.|..|.. . .  .|       . ...||..  .     |||  ..  | .. .   . . .. ||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

GGTLLSYVNKNSG---------LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDA-NWN-----------VKITDFGLASTSYC-----NIMR
||.| .| .|| .         | |.||. .| || .....||.    .|||.|..|||    ..            .||.|||.| .  .     ... 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNI-IHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQ

SYV------GTPGYTPPEVIAGN----DYD-EKCDVWSLGVCLYAMITANLPFSTG-NNYR----KLIDE---------AENLRFPL-----NFSPALVD
..|      ||| |  |... |.    .|.  |||.||||. .| |..   ||..  |..     |||.           ....||.     ..|| . |
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKD

LLKRMLHVRPSSRCRLIDIQNHPWL
|..||| . .. |.   .| ||||.
LIRRMLQYDEKDRISWEEIFNHPWF
Kinase 84394.m00075.AA Ciliate-E2-Unclassified 23-272 24 2.4e-59 203.49 In-house 1-352 (352) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-352/352
Sequence Identity: 24% (85 aa)

FEILEEIGAGAFSTVHIARHITTGVY-----AAAKIVDLSRLGQHEFNGIMREISVFMQVE-----------------HPNVCSCYRMSLEGKS--LILF
..|.. || |.|..|. ..|. .. |     .  .... ... ...   ||.|.   .. .                 ||. .  . .  . .   ... 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

IEYAVGGTLLSYVNKNSG-----------------LKEPEAQ-----RIFFQIYSALRYLHNYYFLVHRDLKLENILFDANW---NVKITDFGLASTSY-
 ||. ||.|. | .|...                 . | .|.     ..| || ..| |||     .|||.|.|||||| |    ..||.|||... .  
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

----------------CNIMRSYVGTPGYT----PPEVIAGNDYD----EKCDVWSLGVCLYAMITANLPFS--TGNN------------YRKLIDEAEN
                 ..| . .|||.|     .|||. |. ||    .|||.|||||.||.|.. ..||.  . .             ||| . .  .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

LR-----------FPLNFSPALVDLLK----RMLHVRPSSRCRLIDIQNHPWL
 .           .| . ||   |...    .|| ..|..|  . .| ||||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 84394.m00075.AA MARK 23-168 37 1.9e-45 146.64 In-house 1-153 (262) Show / Hide 
Range on Protein: 23-168
Range on HMM: 1-153/262
Sequence Identity: 37% (58 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQ-HEFNGIMREISVFMQVEHPNVCSCYRMSL--EGKS-LILFIEYAVGGTLLSYVNKN--SG
...| .|| |....|  |.|. ||.  | ||..  .|   .... .||||.. ....|||. ... .    . .  . |  ||| || |..|. .     
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANW--NVKITDFGLA
|.|.|| ||| || ||. |.|.    ||||.|.|||| |.|   |.||.|||..
LHEEEARRIFRQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFS
Kinase 84394.m00075.AA MARK 181-272 35 1.7e-24 77.14 In-house 167-262 (262) Show / Hide 
Range on Protein: 181-272
Range on HMM: 167-262/262
Sequence Identity: 35% (34 aa)

GTPGYTPPEVIAGNDYD-EKCDVWSLGVCLYAMITANLPFS-TGNNYRKLIDE--AENLRFPLNFSPALVDLLKRMLHVRPSSRCRLIDIQNHPWL
||| | .||.. . .||  | |.||||| ||.|.. ..||  ....| .|  .  ... ..| . |. . .|..|.| | |. |  . .| .|||.
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 84394.m00075.AA TyrKc 23-272 21 4.2e-17 53.83 SMART 1-280 (280) Show / Hide 
Range on Protein: 23-272
Range on HMM: 1-280/280
Sequence Identity: 21% (64 aa)

FEILEEIGAGAFSTVHIARHITTGVYAAAKIVDLSRLGQHEFNGIMREISVFMQV--EHPNVCSCYRMSLEG-------KSLILFIEYAVGGTLLSYVNK
 . ....| ||| .|. .. .   .  | | .  .         .|||... ...  .|||.  .|   ...       . | .  ||. .| |..|  |
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

NSG-LKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNVKITDFGLASTSYCN--------IMRSYV--GTPG-----YTPPEVIAGNDYD
. . |. ..   . .|| .  .|||    ..||||   |.| ..|  |||.||||.   |            |.    |. .      ..||.|  . . 
HRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKCDVWSLGVCLYAMIT--ANLPFS------TGNNYRKLIDEAENLRFPLN--------FSPALVDLLKRMLHVRPSSRCRLIDIQNHPWL
.| |||| |||.. . |  .  .        .    ...... . .. | |         .... .. |.  |  |..|..  .|  |  .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 84394.m00075.AA Pkinase_Tyr 23-168 27 2.7e-13 45.66 Pfam 1-158 (270) Show / Hide 
Range on Protein: 23-168
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

FEILEEIGAGAFSTVHIARHI----TTGVYAAAKIVDLSRLGQHE--FNGIMREISVFMQV-EHPNVCSCYRMSL-EGKS--LILFIEYAVGGTLLSYVN
 ......|.||| .|. ..       |..  | |..      ...      |||... .|   |||. ..|   . .|..  ...  ||. .| ||.|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----NSGLKEPEAQRIFFQIYSALRYLHNYYFLVHRDLKLENILFDANWNVKITDFGLA
|    .  |. ..   . .|| ... ||..   ..||||   |.| . |  |||.|||||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLA
Kinase 84394.m00075.AA Pkinase_Tyr 186-210 40 0.000125 16.3 Pfam 181-205 (270) Show / Hide 
Range on Protein: 186-210
Range on HMM: 181-205/270
Sequence Identity: 40% (10 aa)

TPPEVIAGNDYDEKCDVWSLGVCLY
..||.|. . . .| |||| ||...
MAPECINYGKFTTKSDVWSFGVLMW