Gene 91325.m00119 (T.vaginalis)

91325.m00119

Species: T.vaginalis
Alias: TvagK0413, 91325.m00119
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
91325.m00119.AA Protein None 441 None Fasta, JSON
91325.m00119.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 91325.m00119.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 91325.m00119.AA PH 6-100 34 1.4e-21 80.45 Pfam 1-92 (92) Show / Hide 
Range on Protein: 6-100
Range on HMM: 1-92/92
Sequence Identity: 34% (33 aa)

ILHEGWGTKLGGIFKTWRVRWFTLTKSSLTYSKSKNSRIKGKIDLSKVKEVSPMPDCVYPNAFKVVIPGVRTYQIHCNSPDEMKNWVSIINKVLS
. .||| .|.|  .|.|. |||.|. . | | |....| ||.|.||.. .| . ||   |. |.... . ||| ....|..||. |.. |.....
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 91325.m00119.AA PH 6-102 30 4.4e-19 70.63 SMART 1-82 (82) Show / Hide 
Range on Protein: 6-102
Range on HMM: 1-82/82
Sequence Identity: 30% (30 aa)

ILHEGWGTKLGGIFKTWRVRWFTLTKSSLTYSKSKNSRIKGKIDLSKVKEVSPMPDCVYPNAFKVVIPGVRTYQIHCNSPDEMKNWVSIINKVLSGK
...||| .|..  . .|. |||.|. ..|.| |.|  . ||.|.||.. .|.. |      .|...  .  || ..|.|..||. |.. |.|...  
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDC-TVRE-P------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 91325.m00119.AA AGC 112-369 33 1.9e-160 418.54 In-house 1-395 (395) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-395/395
Sequence Identity: 33% (135 aa)

FEILKVIGKGSYGKVQLVKLR------NTNDIYAMKSISKKL-LGEYE--LISRIITE------------RNVVLKIN----------HPFLIS-ARYAF
||.||||||||.||| ||. .       |...|||| ..||    . .   . ...||            ||.  |.|          |||...   |.|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNDTK--IFLVLDYAQ---------GG-ELYSRLK---EEQKFCEERVKYYCA-M------LAMAIGYLHS-MGICYRD-LKPENILFDKDGYIKLTDFG
|....  ...|..|..         || ||...|.    |..| |||...|.| |      ...|. |||| ||| .|| |||||||.|.||.|||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LVKEHMAKE--------------------------------------------------DKTETFCG--TPEYVAPEIIMNQPYDNSVDWWS--LGTLAY
| || | ..                                                  |.| ||||  ||||.||||.    |. ..||||  || | |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLFGVPPFYNLN----------INAMYRAIC------RDEVDFP----------QNASKEAVDFIIKLLDKDPKSRLGSGPAD-----YKDVLAHPSL
|||.| ||||. |           . |.  |.       ..| ||          .. |.||.|.| ||| |||. |||.|. |     .... .||  
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 91325.m00119.AA Akt 112-369 48 2.4e-137 441.64 In-house 1-264 (264) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-264/264
Sequence Identity: 48% (128 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIY-AMKSISKKLLGEYELISRIITERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFCEE
|..|||.||||.||| |||  .|...| |||...|. . .   .  ..||||.  ..||||...  |.||. .|...|.||..||||.. |. ...| |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RVKYYCAMLAMAIGYLHSMGICYRD-LKPENILFDKDGYIKLTDFGLVKEH-MAKEDKTETFCGTPEYVAPEIIMNQPYDNSVDWWS-LGTLAYEMLFGV
| ..||| .  ||..|||..| ||| ||||||| ||||.|.|||||| ||. .   ||| |||||||| ||||. .. .. .||||. || . |||..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYNLNINAMYRAICRDEVDFP--QNASKEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
||||| ..  |.  |   .| ||   . |.|. |.|..|| |||| |||.|| | ... .|| .
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 91325.m00119.AA SGK 112-369 43 1.3e-131 408.87 In-house 1-283 (283) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-283/283
Sequence Identity: 43% (124 aa)

FEILKVIGKGSYGKVQLVKLRNT------------------NDIYAMKSISKKLLG-------EYELISRIITERNVVLK-INHPFLISARYAFQNDTKI
|..||||||||.||| .||   .                   ..|||| ..|.            ..   | .||||.|| ..|||... .||||...| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FLVLDYAQGGELYSRLKEEQKFCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAKEDKTETFCGTPEYVAPEIIMNQ
..|.||..|||. . |. |..| | |.. | | .. |..||||  | |||||||||| | .|...|||||| || ....|.| |||||||| |||..  |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYDNSVDWWSLGTLAYEMLFGVPPFYNLNINAMYRAICRDEVDFPQNASKEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
|.|..||||.||.. |||..| ||||. | . ||  | . .  .|.. | .| | |  || |||| |||.  .|  ..  ||  
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTK-RDFMEIKNHPFF
Kinase 91325.m00119.AA AktR 112-367 42 5e-115 388.44 In-house 1-266 (268) Show / Hide 
Range on Protein: 112-367
Range on HMM: 1-266/268
Sequence Identity: 42% (113 aa)

FEILKVIGKGSYGKVQLVKLR-NTNDIYAMKSISKKLLGEYELISRIITERNVVL-KINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFCE
|...|..||| .||| ||. . .....||||.|.|| . |.......|||||.   ..||||..   |.||...|.|....| .||||.. || ..|| |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

ERVKYYCAMLAMAIGYLHSM-GICYRDLKPENILFDKDGYIKLTDFGLVK-EHMA-KEDKTETFCGTPEYVAPEIIMN-QPYDNSVDWWSLGTLAYEMLF
|... | |    |. |||.   | |||||||||| |.||..|.||||| | . |  ...|. .|||||||.|||.|.. .... |||||..|.. |||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GVPPFYN--LNINAMYRAICR-DEVDFPQNASKEAVDFII-KLLDKDPKSRLGSGPADYKDVLAHP
| ||||.   |..  .  |..  ....| . |... |.|  |||.|.|. |||.. .. ...  ||
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHP
Kinase 91325.m00119.AA RSK 115-369 40 3.8e-107 362.27 In-house 1-278 (278) Show / Hide 
Range on Protein: 115-369
Range on HMM: 1-278/278
Sequence Identity: 40% (113 aa)

LKVIGKGSYGKVQLVKLR---NTNDIYAMKSISKKLLGEYEL-ISRIITERNVVLKIN-HPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQK---
||| |.|.|||| |..     .|. ||||| ..|. .   .  . .  ||||. . .. |||...  |||| ..|..|...|  ||||. .|..|.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDK---DGYIKLTDFGLVKE-HMAKEDKTETFCGTPEYVAPEIIM---NQP-YDNSVDWWSLGT
|.|.....| | ...|. .||. || .|||||||||.|    .| |||||||. |. .  .. .| |||.| ||.|||...    |  .| ..|||||| 
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAYEMLFGVPPFYN---LNINAMYRAICRDE--VDFP--QNASKEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
| ||||.| |||..    | .   . |.. .  ...|  |. |.|| |.| |.| .||. |||.|| | .....|| .
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 91325.m00119.AA PKA 112-367 40 1.1e-101 344.09 In-house 1-261 (263) Show / Hide 
Range on Protein: 112-367
Range on HMM: 1-261/263
Sequence Identity: 40% (106 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRIITERNVVLKINHPFLI-SARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFCEE
|||....|.||.|.|.|.. ... ..|||| ..|        . ....|.|. . |.|||.. .  . ||.|.....|..|..|||. |.|  ...| . 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RVKYYCA-MLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAKEDKTETFCGTPEYVAPEIIMNQ-PYDNSVDWWSLGTLAYEMLFGVP
  | | |     |. ||||. | |||||||||| ||.|.||.|||| .|.       | | |||||| ||||| .  ..  |||||.|| | ||||.|.|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD---RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYNL--NINAMYRAICRDEVDFPQNASKEA---VDFIIKLLDKDPKSRLGSGPADYKDVLAHP
|||.   . ...|. ||  ...||.. .. |    |.| ||| .|.. |.|.  ..  |.  |.
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHK
Kinase 91325.m00119.AA S_TKc 112-369 35 1.3e-98 334.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRIITERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQG--GELYSRLKEEQK---
.|||..||||..||| ... ..|. |.|.| |.           .|. |...  | .||...   ..||. .....|..|. |  |.|....|. ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAKEDKTETFCGTPEYVAPEIIMNQPYDN-SVDWWSLGTLAYE
   | | ....|.. .. |. |.||.||..|||||||||.|.   ||..|||| ..         ||||||.|.|||..   .|.  ..||||.| . ||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLFGVPPFYNLNINAMYRAICRDEVDFPQNASKEAVDFIIKLLDKDPKSRLGSGPADY--KDVLAHPSL
|| | |||.  ....|.. |.          |.|| ||| |.|.|||. |..   |     |. .|| .
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 91325.m00119.AA PKC 112-369 40 5.8e-97 314.83 In-house 1-262 (262) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-262/262
Sequence Identity: 40% (105 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRIITERNV-VLKINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFCEE
|. |||.||||.||| |.....|. .||.| . | .  . . .    ||. |  |  .|||| .    ||   ..| |. | .|| |     . ..| ||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAKEDKTETFCGTPEYVAPEIIMNQPYDNSVDWWSLGTLAYEMLFGVPPF
. . | |  ..|  .||. || ||||| .|.| |..| ||..|||. ||.| ..|.|.||||||.|.||||.  |.|  |||||..| | |||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YNLNINAMYRAICRDEVDFPQNASKEAVDFIIKLLDKDPKSRLGSGPAD---YKDVLAHPSL
   .   . ..|. |.. .|   |||||. . ....|.|. |||..|..    .|. .||  
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 91325.m00119.AA RSK 112-369 37 9e-94 317.84 In-house 1-271 (271) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-271/271
Sequence Identity: 37% (102 aa)

FEILKVIGKGSYGKVQLVKLR---NTNDIYAMKSISKKLLGEYELISRIITERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFC
.|....||.||..|| ..|      ||. |||| | |. .   .   .  .||..   ..||| .  .|.||  .|.....| ..||.|  ||  .  |.
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

EERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKD----GYIKLTDFGLVKEHMAKEDKTETFCGTPEYVAPEIIMNQPYDNSVDWWSLGTLAYEML
|. || | | .| |  |||| || .|||||||||.| .    | ||..|||. |.  ... .. |||.| .|.|||... | .| ..||||.|.| ||||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

FGVPPFYNLNINAMYRAICRDEVDF-------PQNASKEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
 | .||.| . . .   | |  .         ... |.|| | . ..|. ||  |||.|| . .... || .
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 91325.m00119.AA RSK-Unclassified 112-369 35 3.1e-93 293.2 In-house 1-283 (283) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-283/283
Sequence Identity: 35% (101 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRIITERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLK--EEQKFCE
|.  . ||.|. ||| ||. ..|. |||||  .|. .    .| ...||.|.    |||| .   ..||   . .|...|  ||...  |    | .|||
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

ERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEH---------------------MAKEDKTETFCGTPEYVAPEIIMNQPYD
..|..| .   .|  |||  .. ||||||.||. ...| ..||||.| ..                      .    .|  |||| ||.|||.|      
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

NSVDWWSLGTLAYEMLFGVPPFYNLNINAMYRAICRDEVDFP--QNASKEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
  |||| || . ||||||.||.|  | | ..  | . .| ||  .  |... | | ||| . |  |||..  |  |. .||  
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 91325.m00119.AA Pkinase 112-369 31 3e-85 294.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 112-369
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRII-TERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQGG----ELYSRLK--EE
..|...||.||.|.| . . ..|..|.|.| |.|.   . ......  .|  . ...|||. .  ...|.....| .|..|..||    .|.....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKF--CEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYI----KLTDFGLVKEH-MAKEDKTETFCGTPEYVAPEIIM-NQPYDNSVDWWSL
 .|   |. .| |.  .. .. |.|||||..|||||||||.|..|.|    |..|||| | .   .   . ||||||.|.|||.|. .|.|. .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GTLAYEMLFGVPPFYNL------NINAMYRAICRDEVDFPQNAS---------------------KEAVDFIIKLLDKDPKSRLGSGPADYKDVLAHPSL
| . ||||.| |||..       . ..|.. | . ...|.   .                     .|. ||| ..|.||||.|..      ...| || .
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 91325.m00119.AA p70 156-369 39 1.4e-81 277.36 In-house 74-299 (299) Show / Hide 
Range on Protein: 156-369
Range on HMM: 74-299/299
Sequence Identity: 39% (90 aa)

RIITERNVVLKINHPFLISARYAFQNDTKIFLVLDYAQGGELYSRLKEEQKFCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFG
|   |||.   ..|||..   |||| . | .|.|.|  ||||.  |...  . |. ...| .   .|...||. || ||||||||.. .. | ..|||||
RTFAERNILEEVKHPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFG

LVKEHMAKEDK----------TETFCGTPEYVAPEIIMNQPYDNSVDWWSLGTLAYEMLFGVPPFYNLNINAMYRAICRDE--VDFPQNASKEAVDFIIK
| ||.. .  .          | |||||.|| ||||.|   ..  ||||||| | | || |.|||   |       | .    .  |   ..|. | | |
LCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKK

LLDKDPKSRLGSGPADYKDVLAHPSL
|| ..|..|.|.|| | .|. .||  
LLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 91325.m00119.AA TyrKc 112-363 17 4e-14 5.7 SMART 1-280 (280) Show / Hide 
Range on Protein: 112-363
Range on HMM: 1-280/280
Sequence Identity: 17% (52 aa)

FEILKVIGKGSYGKVQLVKLRNTNDIYAMKSISKKLLGEYELISRIITERNVVLKI--NHPFLISARYAFQND-------TKIFLVLDYAQGGELYSRLK
 . .|..| | .|.| . ...      | |.. .        .  .. | ..  |.  .|| ..    .   .         ...|. |. .| | ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EEQK-FCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAK-------EDKTETF--CGTP----EYVAPEIIMNQPYD
. .. .| .   ..|   |    ||||...  |||   |.| .... .| .|||| ...  .       . .. .   .|         ||| |.   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

NSVDWWSLGTLAYEML-FGVPPFYN------LNINAMYRAICRDEVDFPQN--------ASKEAVDFIIKLLDKDPKSRLGSGPADYKDV
   | || | . .|.. .| .| ..       |. .. .   ..  . |.|        ...|  . . .  . ||..|       ... 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-HECF
Kinase 91325.m00119.AA p70 112-145 54 7.5e-12 39.33 In-house 1-37 (299) Show / Hide 
Range on Protein: 112-145
Range on HMM: 1-37/299
Sequence Identity: 54% (20 aa)

FEILKVIGKGSYGKVQLVKLRN---TNDIYAMKSISK
|| |||.||| |||| .|.  .   |. ||||| . |
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRK
Kinase 91325.m00119.AA Pkinase_C 389-430 35 9.2e-12 44.67 Pfam 1-41 (46) Show / Hide 
Range on Protein: 389-430
Range on HMM: 1-41/46
Sequence Identity: 35% (15 aa)

KISSKIDVSHFDKEFTREAPKLTYEDPTLVDDNVQHQLQGFS
...|..|.|.||.|||.|.|..|. |..    . |.. .||.
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFT
Kinase 91325.m00119.AA S_TK_X 370-433 34 1.8e-10 42.07 SMART 1-79 (79) Show / Hide 
Range on Protein: 370-433
Range on HMM: 1-79/79
Sequence Identity: 34% (27 aa)

AGLSEEALYK--KQIPMKWKPKIS----SKIDVSHFDKEFTREAPKLTYEDPTLVDDNVQHQ---------LQGFSLIN
.|.  ..||.  |.|.  .||||.    | .|.| ||.|||.|.|.||  ||.|.. . | .           ||. ..
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 91325.m00119.AA Pkinase_Tyr 112-264 21 5.4e-07 24.3 Pfam 1-165 (270) Show / Hide 
Range on Protein: 112-264
Range on HMM: 1-165/270
Sequence Identity: 21% (35 aa)

FEILKVIGKGSYGKVQLVKLR----NTNDIYAMKSISKKLLGEYE-LISRIITERNVVLKI-NHPFLISARYAFQ-NDTK--IFLVLDYAQGGELYSRLK
 ...|..|.|..|.| . ...    ||.   | |.. |    . . ..   . | ..  .. .|| ...   .    .    |..|. |...| |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----EQKFCEERVKYYCAMLAMAIGYLHSMGICYRDLKPENILFDKDGYIKLTDFGLVKEHMAKE
.    .|... ..   .|.  |..  ||.|...  |||   |.| .... .| .|||| . .. ..
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDD