Gene 85862.m00248 (T.vaginalis)

85862.m00248

Species: T.vaginalis
Alias: 85862.m00248, TvagK0290
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
85862.m00248.AA Protein None 1117 None Fasta, JSON
85862.m00248.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 85862.m00248.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 85862.m00248.AA TKL 230-474 26 2.4e-85 289.83 In-house 1-364 (364) Show / Hide 
Range on Protein: 230-474
Range on HMM: 1-364/364
Sequence Identity: 26% (99 aa)

LGSGTFADVYLG-YQKST-------GLLVGFKKLKTQQFKFH-------------------------DFQMYKREIQIFSSLKHYAILPFVGASIQHP--
.|||.|. || | ..  .       |  |  ||.|... ...                          ..  ..|| . |.|.|  |..|.|.... |  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCLVTEFMSNGNLFERLRKATTPFDGTRKTIC-ALGIAEGMAYMHS--------KNIMHRDLKSLNILLDSD--------------DF
            .|.|.|....|.|...|           ...  ||.|| ||.|.||        ..| |||||| |||.|..              ..
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

PKICDFGMSRNIEGAD--------------------VLTGGIGTYRWMAPEVLDSR----------------PYTFKADVYSYAIVLWELLTQDVPFHGL
.|||||| ||....                       .   .||.||||||||.                  .|. |.||||..|||||.||  .|....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

SEIQVS---------MNVIQKDARPLFP------------QNCPQKIVKLIKRCWDRDPDQRPDFETIAKMF
 ....          | |..|  ||. |             .||. . ||...||| ||..|| |..| | .
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 85862.m00248.AA MLK 224-474 30 9.4e-79 267.95 In-house 1-291 (291) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-291/291
Sequence Identity: 30% (90 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFK---FHDFQM-------YKREIQIFSSLKHYA----ILPFVGASIQH-P-YCLVTEFMSNGNL
..... .|||.| .|..|. . .   .  | .. ....   | | .         ..|. ... |.|      | .|.|...|. . .|.|.|....| |
IQFHEWIGSGSFGKVWKGRWRNKDIVA--KIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSL

FERLRKATT-------------PFDGTRKTICALGIAEGMAYMHSKN---IMHRDLKSLNILLDS------DDFPKICDFGMSRNIEGA-DVLTGGIGTY
.. |. |..               |   .   || .|.||.| ||.    | |||||| |||.|       ..  |||||| || .    .  .. .|||
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTY

RWMAPEVL---DSRPYTFKADVYSYAIVLWELLTQDVPFH-GLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAKMF
.||||||.    . .|. |.||.|...||||.||  ||.. ....... . |...  ||  |..||  . ||.|.||. || .||.|  | . .
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 85862.m00248.AA TyrKc 224-474 31 1.9e-69 237.98 SMART 1-280 (280) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-280/280
Sequence Identity: 31% (90 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFHDFQMYKREIQIFSSL--KHYAILPFVGASIQ--------HPYCLVTEFMSNGNLFERLRK
 .| | ||.| |  ||.|  |   . |  |.||         ..  ||..| ..|  .|  |. ..|. .|        .|...|.|.|..|.| ..|||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

ATTPFDGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLDSDDFPKICDFGMSRNIEGA-------DVLT-----GGI--GTYRWMAPEVLDSRPYTF
    .    .   .. ||.||.| ||||. ||||   |.|....   ||.|||.||.|.         |. .     ||     .||||||... . .|.
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KADVYSYAIVLWELLTQ-DVPFHG-----LSEIQVSMNVIQKDARPLFPQN--------CPQKIVKLIKRCWDRDPDQRPDFETIAKMF
| ||.|. ...||..|  . |  |     .| ..| .. ...  |.  |.|        ||... ...|.||..||..|| |..| . |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV-IEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 85862.m00248.AA HH498 224-474 31 7.2e-68 214.12 In-house 1-284 (284) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-284/284
Sequence Identity: 31% (90 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFH-D-----FQMYKREIQIFSSLKHYAILPFVGASIQHP--YCLVTEFMSNGNLFERL----
.| ..  ||| | .||.|.    . .|  |  . . |    |       |. ||. | . | |     ||.|..  |    .||.. .|| || .|    
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

-------------RKATTPFDGTRKTICALGIAEGMAYMHS---KNIMHRDLKSLNILLDSDDFPKICDFGMSR--NIEGADVLTGGIGTYRWMAPEVLD
             ..     |   | . .. .| || | |.   . | |||| | |||.. |   .. ||| ||  .  . | .|  .|  |||||||  
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-SRPYTFKADVYSYAIVLWELLTQDVPFHGLSEIQVSMNVIQKDARPLFPQN----CPQKIVKLIKRCWDRDPDQRPDFETIAKMF
 .  |. |.||.|||...||..|  |||| .  .  .  .  .  ||  ||      |.... || .||.  |. ||||  |  . 
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 85862.m00248.AA Pkinase 224-474 27 1.2e-66 232.48 Pfam 1-293 (293) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFHDFQMYKR--EIQIFSSLKHYAILPFVGASI--QHPYCLVTEFMSNG----NLFERLR-KA
... ...|||.|. ||... |.|| .|  |..| .  |    |   |  ||||  .|.|  |. . ..    .|.| .|.|.. .|     ||.... ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIY-MVMEYCEGGLYVMDLFDYISTWR

TTPF---DGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLDSDDFP----KICDFGMSRN--IEGADVLTGGIGTYRWMAPEVLD-SRPYTFKADVY
 ..|   . . | . .. |..|..|.||..|.|||||. |||.|... .    |||||| ..   .     .|.  ||...|||||.  ...|. |.|..
HGCFYFSEWECKFY-MYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SYAIVLWELLTQDVPFHGL------SEIQVSMNVIQKDARPLFPQNCP-------------------QKIVKLIKRCWDRDPDQRPDFETIAKM--F
|. ..|.|.|.   || |       ...|.  .. ... .  .|. |.                   .   ..||.|...|| .|| .| | .   |
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 85862.m00248.AA Dicty4 224-470 36 9.9e-65 214.85 In-house 1-269 (277) Show / Hide 
Range on Protein: 224-470
Range on HMM: 1-269/277
Sequence Identity: 36% (100 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKL---KTQ--QFKFHDFQMYKREIQIFSSLKHYAILPFVGASI---QHP--YCLVTEFMSNGNLFERLRK
   ..|.|.| |. ||.|  .  |  |  |||   ..   ..   .|   ..|. | ... |  |. | ||..    ||   | |||.|. |||.. |..
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEF---RKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHD

------ATTPFD-GTRKT---ICALGIAEGMAYMHSKN--IMHRDLKSLNILLDSDDFPKICDFGMSR----NIEGADVLTGGIGTYRWMAPEVLDSRPY
        .. | ...|    . |. .| ||.. |. |  | |||||| |.| | .   |.|||| |.     ..  | ... .||  ||||||. ..||
KPSEQQQSIKLDWPLIKRAMRM-AFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

TFKADVYSYAIVLWELLTQDVPFH--GLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETI
. ||||||..|||||.|| . |.   . .  |.   | .|  ||  |..|| .. .||..||| || .|| || |
NEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEI
Kinase 85862.m00248.AA LRRK 224-476 27 2e-64 220.36 In-house 1-351 (351) Show / Hide 
Range on Protein: 224-476
Range on HMM: 1-351/351
Sequence Identity: 27% (96 aa)

FELQKRLGSGTFA-DVYLGYQKS--------------------------TGLLVGFKKLKT--------------------------------QQFKFHD
.. .. .|.|.|.  || .  ..                           .  |  ||...                                 ... . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FQMYKREIQIFSSLKHYAILPFVGASIQHPYCLVTEFMSNGNLFERLRKAT-TPF-----DGTRKTIC--ALGIAEGMAYMHSKN--IMHRDLKSLNILL
|. . .|. | |.|.|  |.. .| .| ||.|.|.|....|.| ..|..   ..|     . .. ..   || ||.||.|.||.|  | |||||| ||||
FREFRHEVWIMSHLNHPNIVSLKGFCI-HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DSDDFP------------KICDFGMSR--NIEGADVLTGGIGTYRWMAPEVLDSR---PYTFKADVYSYAIVLWELLTQD-VPFHGLS-------EIQVS
 | . .            ||.||| ||   . .  |. |  |. .|||||..       || |.|.||....|||||| .  || ...       ..|..
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

MNVIQKDARPLFPQN-CPQ-----KIVKLIKRCWDRDPDQRPDFETIAKMFKC
 . |..  || .||. ||.        .||. ||. ||..|| |..| |  . 
-DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 85862.m00248.AA TKL-Unique 226-474 28 2.8e-63 216.54 In-house 1-290 (290) Show / Hide 
Range on Protein: 226-474
Range on HMM: 1-290/290
Sequence Identity: 28% (84 aa)

LQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFH-DFQM-YKREIQIFSSLK-HYAILPFVGASI----QHP-YCLVTEFMSNGNLFERLR-----
  . .|.|... || |  ...   .  |...  . ... ..    ..|. . . |. |  |. ..|...    . | .|.|.|... |.| . |      
FWNKIGEGGYGQVYKGKWRGYPVAI--KQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

----KATTPFDGTRKTICALGIAEGMAYMHSKN--IMHRDLKSLNILLDSD-----DFPKICDFGMSRNIEGADVLTGG----------IGTYRWMAPEV
    .  ....  ..   |. || || | |...  |.||||||.|.|.|..        |||||| |..    .  | .          .|..|||||||
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

LDS--RPYTFKADVYSYAIVLWELLTQDV------PFHGLSEIQVSMNVIQ--KDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAKMF
| .    |. |.||||..|||||..| ..      |..|.. .|.   | .  .  ||  |..||. . .||..||..||.||| |..| .  
LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 85862.m00248.AA Dicty4-Unclassified 224-474 36 3.7e-63 215.16 In-house 1-263 (263) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-263/263
Sequence Identity: 36% (97 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFH--DFQMYKREIQIFSSLKHYAILPFVGASIQHP------YCLVTEFMSNGNLFERLR---
    . .| | |. |. |  |  |  |  ||.   .|||     | .|.|. |  |. |   .   |..|  |      .| |.|||  |||||      
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCIN-PRSHKSTMCIVMEFMHKGNLFEVIHSKP

---KATTPFDGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLDSDDFPKICDFGMSRNIEGADVLTGGIGTYRWMAPEVLDSRPYTFKADVYSYAIV
   .     | |     |. || ||...|..|. |||.|| |||.| .   || |||.|| |.    .|   || .| .||.|    |. |.||||||..
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMM

LWELLTQDVPFHGLS-EIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAKMF
|.||.| | |. .    . .   |  |  ||  | ||.  . |||| ||  ||  || .. | .  
LYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 85862.m00248.AA Pkinase_Tyr 224-474 32 5.8e-63 213.86 Pfam 1-270 (270) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-270/270
Sequence Identity: 32% (88 aa)

FELQKRLGSGTFADVYLGYQK----STGLLVGFKKLKTQQFKFHD--FQMYKREIQIFSSL-KHYAILPFVGASI--QHP--YCLVTEFMSNGNLFERLR
 .. | ||.| | .||.|. |    .|.. |  |.|  ..   ..   ..  ||..| ..| .|  |. ..|. .  . |  ...|.|.| .|.| . ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KA---TTPFDGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLDSDDFPKICDFGMSRNIEGADVL----TGGIGTYRWMAPEVLDSRPYTFKADVYS
|      |..  ..   .. ||.||.| .|||. ||||   |.|.... . ||||||..| |.  |      .||    .|||||..  . .| | ||.|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

YAIVLWELLT-QDVP-FHGLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAKMF
. ...||..|  . | . |.|  .|   . ..  |   |.|||..| .|.|.||. ||..|| |. |  ..
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 85862.m00248.AA TK 224-474 17 2.6e-62 207.38 In-house 1-486 (486) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-486/486
Sequence Identity: 17% (87 aa)

FELQKRLGSGTFA---DVYLGYQKSTG-------------------------LLVGFKKLKTQ-QFKFHDFQM--------------YKREIQIFSS--L
 .| | ||.| |    .||.|  .. .                           |  | ||        .|..                .|......  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

KHYAILPFVGASIQH-------------PYCLVTEFMSNGN----LFERLRKATTPFDGTRKTI------------------------------------
.|  |. ..|.. |.             |...|.|.|..|.    | . |||   .|     ..                                    
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------CALGIAEGMAYMHSK------NIMHRDLKSLNILLDSDDF-----------PKICDFGMS--
                                      ... ||.||.|.|||      |. ||||   |.|.....             ||.|||.|  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------RNIEGADVLT---------------------------GGIGTYRWMAPEVLDSRP---------YTFKADVYSYAIVLWELLTQD-VPFHGLSE
      | |.  |  .                           ||    ||||||.|..|          .| | ||.|. ...||..|   .|..|   
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

I---------QVSMNVIQKD--------------ARPLFPQNCP--------------QKIVKLIKRCWDRDPDQRPDFETIAKMF
          |  |. ...                |.  |..||              . .  |...||..||..||.|... ...
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 85862.m00248.AA S_TKc 224-474 27 4.7e-59 203.43 SMART 1-231 (231) Show / Hide 
Range on Protein: 224-474
Range on HMM: 1-231/231
Sequence Identity: 27% (75 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFKFHDFQMYKREIQIFSSLKHYAILPFVGASIQHPYCLVTEFMSN--GNLFERLRKATTP----
.|. . .|.|.|. ||... |.|| .|  |..|         .. .||||| .. .|  |  . ..   . ...|.|....  |.||....|  ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FDGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLDSDDFPKICDFGMSRNIEGADVLTGGIGTYRWMAPEVLDSRPYTF-KADVYSYAIVLWELLT
 |.  .    .  |.....|.||..|.|||||  |||||.    ||||||..| .      |  .||  .||||||   .|.. |.|..|  ..|.|.|.
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

QDVPFHGLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAK---------MF
   ||.   ..|. ...|            ..    .|..|...||..||    . .          |
GYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 85862.m00248.AA Dicty5 264-478 35 5.9e-59 201.54 In-house 39-260 (260) Show / Hide 
Range on Protein: 264-478
Range on HMM: 39-260/260
Sequence Identity: 35% (80 aa)

DFQMYKREIQIFSSLK--HYAILPFVGASIQHPYC--LVTEFMSNGNLFERLRKATT----PFDGTRKTICALGIAEGMAYMHSKNIMHRDLKSLNILLD
| . ..||. | |  .  |  .  . ||  .       |||. .|| ||. |.        |     .   |..|| .| ..||.|| ||||||.|.|. 
DWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQPIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLIT

SDDFPKICDFGMSRNIEGADVLTGGIGTYRWMAPEVLDSRPYTFKADVYSYAIVLWELLTQDVPFHGLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKR
 .   || ||| ||... .   |  .||  |||.|.  ..||. |.||||..|||||..|.. |.  .  .    . ..|  ||  |  ||  | .||| 
ENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRKEPYDNINNWNIP-VMVMKGERPTIPKDCPTEISNLIKK

CWDRDPDQRPDFETIAKMFKCGL
||   | .|| |  | |.|.   
CWQQKPHNRPSFKEICKYFESII
Kinase 85862.m00248.AA DRK 224-476 33 5e-56 188.24 In-house 1-258 (258) Show / Hide 
Range on Protein: 224-476
Range on HMM: 1-258/258
Sequence Identity: 33% (88 aa)

FELQKRLGSGTFADVYLGYQKSTGLLVGFKKLKTQQFK-FHDFQMYKREIQIFSSLKHYAILPFVGASIQHP-YCLVTEFMSNGNLFERLRKATTPFDGT
   . | | | ...|..|     |  |  |.|.          .  .||| . . | |  |  | |.    |  | ..|.|. | |   |       |  
IKIGNRIGRGNYGEVFRGTWR--GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWP

RKTICALGIAEGMAYMHSKN--IMHRDLKSLNILLDSDDFPKICDFGMSR---NIEGADVLTGGIGTYRWMAPEVLDSRPYTFKADVYSYAIVLWELLTQ
.    .. .| || | |. |  |.|||||| | | |     |. ||| |     ..        .||  | ||||| . .|| ||||||.||||||..| 
LMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTR

DVPFHGLSEIQVSMNVIQKDARPLFPQNCPQKIVKLIKRCWDRDPDQRPDFETIAKMFKC
  |. |    || . | .   ||  ||.|| | ..|...||. || .|| .. . .    
QDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA