Gene 93204.m00188 (T.vaginalis)

93204.m00188

Species: T.vaginalis
Alias: TvagK0324, 93204.m00188
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
93204.m00188.AA Protein None 1103 None Fasta, JSON
93204.m00188.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of 93204.m00188.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 93204.m00188.AA TKL 216-458 25 7e-78 265.05 In-house 1-364 (364) Show / Hide 
Range on Protein: 216-458
Range on HMM: 1-364/364
Sequence Identity: 25% (96 aa)

IGQGAFSTVYHG-FQKST-------GHPVAMKKLNS--GILTKE-----------------------QFETYLREIRILTSLNHFAITPFVGVTPKEP--
||.|.|..||.| ..  .       | .||.||..|    .. .                        ...  .||... .|.|  | .|.|.   .|  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YYIITQLMRGDCLFYRLHAQRNPLSPTKLTIIALGIAYGLAYLHSEK--------IMHRDIKSLNILLDNDDY--------------P
            ..|..... | .|...||       . ..  .||.|| |..||||..        | |||.|| |||.|..                .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

HICDFGCARFMDGR---------------------RYSIKVGTTQWMAPEM-----YEID-----------CYSFKVDIYSYGILLWEMLTGQIPFANLK
 ||||| .|||...                     . . ..||..|||||.     .  .            || |.|.||.||.|||.||...|.....
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

DVDIL---------PMVIN-GERPPIP------------SSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
  ...          ||.. |.|||||            ..|| ...||.. ||| ||.||||  .|.. .
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 93204.m00188.AA MLK 210-458 32 2.5e-74 253.25 In-house 1-291 (291) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-291/291
Sequence Identity: 32% (95 aa)

FELSKKIGQGAFSTVYHGFQKSTG---HPVAMKKLNSGI----LTKEQFETYLREIRILTSLNHFA----ITPFVGVTPKE-P-YYIITQLMRGDCLFYR
......|| |.|  |. |  . .      || |. .. |     | .. .   .|.|.|  |.|      | .|.||  .. . ..|... ..| .|.  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHAQRN-------------PLSPTKLTIIALGIAYGLAYLHSEK---IMHRDIKSLNILLDN------DDYPHICDFGCARFMDGRRYS---IKVGTTQW
||..|.               ..  .  .|| .| |..||||..   | |||.|| |||.|.      ..   ||||| .|..  .  .    . ||  |
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEMY---EIDCYSFKVDIYSYGILLWEMLTGQIPFA-NLKDVDILPMVINGE-RPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
||||.    . . || |.|..|.|..||||||...|..  ..   |. .|.. . ||||||.|| ...||.| ||. ||.||||..|||| .
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 93204.m00188.AA Pkinase 210-458 29 5.1e-72 250.37 Pfam 1-293 (293) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-293/293
Sequence Identity: 29% (86 aa)

FELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSGILTKEQFETYLR--EIRILTSLNHFAITPFVGVT-PKEPYYIITQLMRGD----CLFYRLH-AQR
... .|||.|.|..||..  |.||. ||.|...     ... .| .|  ||.|. .|||  |  . ..   |  .|... ...|.     || ...  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NPL--SPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYP----HICDFGCAR---FMDGRRYSIKVGTTQWMAPEMYE-IDCYSFKVDIYSY
...  |.  .  ... |. ||.|.||..|.|||.|. |||.||....    .|||||.|.      .. ..  .||  .||||       |. |||..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLWEMLTGQIPFANL----KDVDILPMVINGERPPIPSSCP-----------------------SGLAKLIKSCWDVDPNKRPSSAQIVQV--F
|..|.|||.|. || .     . .| . |. .  .||.....|                       . . ..||.|...||.|||. .||.|   |
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 93204.m00188.AA S_TKc 210-458 28 1.2e-62 215.33 SMART 1-231 (231) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

FELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSGILTKEQFETYLREIRILTSLNHFAITPFVGVTPKEPYYIITQLMRG--DCLFYRLHAQRNP----
.|. .|||.|||..|| .  |.||. ||.|...         |. .|||.|| . .|  |  . .|   . .|... .. |    || ... .. .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LSPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCARFMDGRRYSIKVGTTQWMAPEMYEIDCYSF-KVDIYSYGILLWEMLTG
 ...     ..  |. .|.|.|| .|.|||.|  |||||.     ||||| ||..     .  .||  .||||.     |.. |.|..| |..|.|||.|
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

QIPFANLKDVDILPMVINGERPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQ---------VF
. ||    .  .. ..            .. .  .|. |...||.|||.  .. |          |
YPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 93204.m00188.AA TyrKc 210-458 29 1.9e-60 208.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-280/280
Sequence Identity: 29% (85 aa)

FELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSGILTKEQFETYLREIRILTSL--NHFAITPFVGVTPK--------EPYYIITQLMRGDCLFYRLHA
 .| ||.| ||| .||.|  |    .|| |.|...       |  .||.||...|  .|  |  ..||  .        ||..|.. .| . .|  .|..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QRNPLSPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCARFMDGR--------RYSIKV--GTTQ-----WMAPEMYEIDCYSF
 |. |.. .|  ... || | .|||| .. |||.   |.|....    |.||| .|. .           |. |   |.       |||||     ....
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KVDIYSYGILLWEMLT-GQIPFAN-----LKDVDILPMVINGERPPIPSS--------CPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
| |..|.|...||..| || |  .     ... ...  | .|.|.|.| .        ||. . ...|.||. ||..||. ..|.. |
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 93204.m00188.AA TKL-Unique 212-458 29 1.1e-59 204.57 In-house 1-290 (290) Show / Hide 
Range on Protein: 212-458
Range on HMM: 1-290/290
Sequence Identity: 29% (88 aa)

LSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNS---GILTKEQ-FETYLREIRILTSLN-HFAITPFVGVTP----KEP-YYIITQLMRGDCLFYRLH---
 ..|||.|....||.|  ...  |||.|...      ....| ||   .|....  |. |  |. ..|..     ..| ..|..  . |  |   ||   
FWNKIGEGGYGQVYKGKWRGY--PVAIKQFHPNEDSSNEMMQEFE---NEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNN

------AQRNPLSPTKLTIIALGIAYGLAYLHSEK--IMHRDIKSLNILLDND-----DYPHICDFGCARFMDGR-RYSIK----------VGTTQWMAP
      .. ..|.. .   .|. || |. |||...  |.|||.||.|.|.||.         ||||| ..| . . . ...          .|...||||
NNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAP

EMYEI--DCYSFKVDIYSYGILLWEMLTGQI------PFANLKDVDILPMVIN---GERPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
|. .   . || |.|.||.|| |||..|..|      |. .. .  .. ||     . |||||..||  . .||. ||. || .|||  .|.   
EVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 93204.m00188.AA Dicty5 211-462 34 1.9e-56 192.8 In-house 2-260 (260) Show / Hide 
Range on Protein: 211-462
Range on HMM: 2-260/260
Sequence Identity: 34% (90 aa)

ELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSGILTKEQFETYLREIRILTSLN--HFAITPFVGVTPKEPYY--IITQLMRGDCLFYRLHAQRN----
 . . |  ||  .|| |  |  |  || | . .        . . ||. |.      |  .. . |   ..  |  ..| . .   ||  |  ||.    
SFHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

PLSPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCARFMDGR-RYSIKVGTTQWMAPEMYEIDCYSFKVDIYSYGILLWEMLTG
|..      .|..|| .. .|||  | |||.||.|.|.  .    | |||  || | |  . . |||  |||.|..    |  |.|.||.|| ||||.| 
PIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTR

QIPFANLKDVDILPMVINGERPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVFERGE
  |. |.   .|  ||  |||| ||  ||.  ..|||.||   | .|||   |...||.  
KEPYDNINNWNIPVMVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase 93204.m00188.AA STE 210-453 24 1.2e-54 187.83 In-house 1-350 (359) Show / Hide 
Range on Protein: 210-453
Range on HMM: 1-350/359
Sequence Identity: 24% (88 aa)

FELSKKIGQGAFSTVYHGFQK------STGHP---------VAMKKLN-----SGILT-----------KEQFETYLREIRILTSLN--HFAITPFVGVT
.|. .|||.||| ||| .  .      .||           .|.|..|     . . .           .|... .|.||.|.  .|  |  |  . |  
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

PKEP--------YYIITQLMRGDCLF---YRLHAQRNPLS----------PTKLTIIALGIAYG-LAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCA
 ||          .|.  .| | .|     . .   .||.           . . .|.  |  | |.|||| .|.|||||. ||||       .||||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

RFMDG------------------RRYSIKVGTTQWMAPEMYEI--DC----YSFKVDIYSYGILLWEMLTGQIPFANLKDV----------------DIL
  ..                    .    |||  |||||. .    .    |..|.||.| |....||.||. |......                 . |
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

PMVINGERPPIPS-------------------SCPSGLAKLIKSCWDVDPNKRPSSAQ
 ...||. ||.|.                   .. . .   |. | . ||||||.. |
-CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 93204.m00188.AA Pkinase_Tyr 210-458 31 6.4e-54 183.23 Pfam 1-270 (270) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-270/270
Sequence Identity: 31% (87 aa)

FELSKKIGQGAFSTVYHGFQK----STGHPVAMKKLNSGILTKEQ--FETYLREIRILTSL-NHFAITPFVGVTP--KEP--YYIITQLMRGDCLFYRLH
 .. ||.|.||| .||.|  |    .|. ||| |.|.    ..||   |  .||..|...| .|  |  ..||    .||  .||.. .| . .|   |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

AQ---RNPLSPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCARFM-DGRRYSIKVGT-----TQWMAPE--MYEIDCYSFKVD
..   ..||..  |  ... || |..||.| .. |||.   |.|....    ||||| || . .   | .....       |||||  .| .  .. | |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGK--FTTKSD

IYSYGILLWEMLT-GQIP-FANLKDVDILPMV-INGERPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
..|.|.|.||..| |..| ...... ... ..  .|.| |.|  ||  . .|.|.||. ||..||. ..|.. .
VWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 93204.m00188.AA HH498 210-458 30 1.2e-53 168.27 In-house 1-284 (284) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-284/284
Sequence Identity: 30% (87 aa)

FELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSG-ILTKEQ-----FETYLREIRILTSLNHFAITPFVGVTPKEP--YYIITQLMRGDCLFYRL----
.|  .||| |.|  || |     .  || |   .  .. |          . ||. |.  |||.    ||. .  .|    |.||   .  || .|    
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIP

----------HAQR---NPLSPTKLTIIALGIAYGLAYLHS---EKIMHRDIKSLNILLDNDDYPHICDFGCARFMDGRRYSI--K-VGTTQWMAPEMYE
          | |.     ...    .|.. .| |  |||.     | |||  | |||.. |    . |||  ||   .      |  |   ||||| . 
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFS

-IDCYSFKVDIYSYGILLWEMLTGQIPFANLKDVDILPMVINGE-RPPIPSS----CPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
    || |||..||.. .|||.|. .||. .| .     . . . ||||| .     |     ||  ||.  |. ||. .||| . 
QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 93204.m00188.AA Fer 210-459 28 6.2e-53 178.63 In-house 1-283 (283) Show / Hide 
Range on Protein: 210-459
Range on HMM: 1-283/283
Sequence Identity: 28% (80 aa)

FELSKKIGQGAFSTVYHG-------FQKSTGH---PVAMKKLNSGILTKEQFETYLREIRILTS-LNHFAITPFVGV-TPKEPYYIITQLMRGDCLFYRL
..| ||.| ||| .|| |        .|.      .|..||...  .|||| .  ..| ||. . ..|  .  | || . ..|..|.  .. |..|  .|
VTLGKKLGEGAFGEVYKGRRTLKCKKGKWHVVNKVAVKVKKCKCEDATKEQIKEFMHEARIMRNNYDHPNVVKFYGVCVDEQPIMIVMEFCNGGSLDSYL

HAQRNP-LSPTKLTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDN-DDY--PHICDFGCARFMDGRRYSIKVG------TTQWMAPEMYEIDCYSFKVD
    |  .|  ..  .....| |..|||| ...|||| . |.|... ...  . | ||| .|  ..  |. | .       . |.|||  .  .||.| |
KKNKNKTVSDNEKIRMCYQAACGMEYLHSKNCIHRDIAARNCLYHKDKVKKKCKISDFGMSRQCSDYGYDYKMKEKACKVPIRWLAPETWQTGIYSPKTD

IYSYGILLWEMLT-GQIPFAN------LKDV-DILPMV-IN-GERPPIPSSCPSGLAKLIK-SCWDVDPNKRPSSAQIVQVFE
..|.|...||  | |. |...      .. | . . .. |. | ..|.|...|. ...... .||..||..||. ..|.| ..
VWSFGVMCWEIFTNGAEPYPGQPHGMKMTNVKKQARKWIIKKGYMMPMPNHMPPEIMQIMMKQCWQKDPEDRPTMKEICQKLK
Kinase 93204.m00188.AA Dicty4-Unclassified 210-458 33 1.4e-52 178.37 In-house 1-263 (263) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-263/263
Sequence Identity: 33% (88 aa)

FELSKKIGQGAFSTVYHGFQKSTGHPVAMKKLNSGILT--KEQFETYLREIRILTSLNHFAITPFVG--VTP---KEPYYIITQLMRGDCLFYRLH----
    . ||.|.|| |. |  |  |  || ||.|..      |  . ...|. || |. |       |  . |   |  . |.. .|    ||   |    
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPS

AQRNPLSPTK--LTIIALGIAYGLAYLHSEKIMHRDIKSLNILLDNDDYPHICDFGCARFMDGRRYSIKVG-TTQWMAPEMYEIDCYSFKVDIYSYGILL
 |  |..        .|. || |...||.  . |||||| |||.| .    | ||| .|  |       .. |  | .||      |  | |.|||...|
EQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMML

WEMLTGQIPFANLK-DVDILPMVIN-GERPPIPSSCPSGLAKLIKSCWDVDPNKRPSSAQIVQVF
.|..||  |.      ...   |   . || ||..|.  . |||| ||  ||||||.  ||.|  
YELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 93204.m00188.AA LRRK 210-460 26 6.5e-52 178.79 In-house 1-351 (351) Show / Hide 
Range on Protein: 210-460
Range on HMM: 1-351/351
Sequence Identity: 26% (92 aa)

FELSKKIGQGAFS-TVYHGFQKS--------------------------TGHPVAMKKLNS--------------------------------GILTKEQ
..  ..||.|.|  .|| .  ..                           . .|| ||.|                                 .. . . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FETYLREIRILTSLNHFAITPFVGVTPKEPYYIITQLMRGDCLFYRLHAQR-NP-------LSPTKLTIIALGIAYGLAYLHSEK--IMHRDIKSLNILL
| .. .|. |. .|||  | . .|..  .|. ... ...   |  .||. . ..       .|.. .  ||| || |..|||| .  | ||| || ||||
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DNDDYP------------HICDFGCAR--FMDGRR-YSIKVGTTQWMAPEMYEID---CYSFKVDIYSYGILLWEMLTGQ-IPFANLK-------DVDIL
   . .            .|.|||  |  . ..    . .||. .|||||    .    |. |||.||.|..||| ||.| .|| ...          | 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

PMVINGERPPIPSS-CPS-----GLAKLIKSCWDVDPNKRPSSAQIVQVFER
  .|.| ||.||.. ||       . .||..||. ||.|||.. |||.. . 
DKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 93204.m00188.AA TK 210-458 16 8.8e-52 171.47 In-house 1-486 (486) Show / Hide 
Range on Protein: 210-458
Range on HMM: 1-486/486
Sequence Identity: 16% (78 aa)

FELSKKIGQGAFS---TVYHG---------------------------FQKSTGHPVAMKKLNSGILTKEQFE-------------TYLREIRILTS--L
 .| ||.|.|.|    .|| |                            .. |   |.|.|. ..   .|.|.               ..|. .. .  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

NHFAITPFVG----VTPK---------EPYYIITQLMRGDC----LFYRLHAQRNP--------------------------------------------
.|  |  ..|    . ||         ||..|.. .| . .    |   |.. |..                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSPTKLTIIALGIAYGLAYLHSE------KIMHRDIKSLNILLDNDDY-----------PHICDFG---
                               |..  |  ... || |..||||       .. |||.   |.|.....              |.|||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----CARFMDGRRYSIKVGTTQ----------------------------WMAPEMYE---------IDCYSFKVDIYSYGILLWEMLT-GQIPFANLK
      || .. . .  ....                              |||||  .            .. | |..|.|.|.||..| || |..   
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DV----------DILPMVING--------------ERPPIPSSCP--------------SGLAKLIKSCWDVDPNKRPSSAQIVQVF
.           ... .. .|               |.| |  ||                .. |...||. ||..||. .|... .
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL