Gene 81869.m00187 (T.vaginalis)

81869.m00187

Species: T.vaginalis
Alias: 81869.m00187, TvagK0270
External Links:
Annotation:

Classification

Group: TKL
Family: TKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
81869.m00187.AA Protein None 800 None Fasta, JSON
81869.m00187.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 81869.m00187.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81869.m00187.AA TKL 213-458 27 2.4e-90 306.43 In-house 1-364 (364) Show / Hide 
Range on Protein: 213-458
Range on HMM: 1-364/364
Sequence Identity: 27% (102 aa)

IGSGISSNVFYGRCKS--------TGLPVAIKKLKFKKLTGIKL-------------------------QTFQREISILAATSHPCLLKFVG-ATDTQP-
|||| .. |. |...         || .||.||.| .      .                         ... .|| ..  ..|| ...|.| ... .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCIITEWMDRDTLYRELHKTKMLNATKKTIVAFDIARGMQYLHSKH--------IIHRDLKSLNVLLNEEGQ--------------AK
            .||..|.... .|.  ||        ..   | ||||||.||||..        |||||||| |.|..| ..              .|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCK

IGDFGYSRSYDSEDS-------------------LLTQNIGTPHWMAPELLDGTTNYTNKV---------------DVYAYAIVLWEIITGLQPYQGLDP
|.||| ||. . . .                    .   .||| |||||.|.|..|||.||               |||...||||||.|. .||.....
ICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPY

PQII---------AQVMIHDLRPPLP------------QTVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
...|         ..|  . ||||.|             .. |..|.|...||| .|. ||||.||.| .
MPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 81869.m00187.AA TKL-Unique 209-458 32 1.4e-78 267.38 In-house 1-290 (290) Show / Hide 
Range on Protein: 209-458
Range on HMM: 1-290/290
Sequence Identity: 32% (94 aa)

MIKEIGSGISSNVFYGRCKSTGLPVAIKKLKF-KKLTGIKLQTFQREISILAATS-HPCLLKFVGATD----TQP-YCIITEWMDRDTLYRELH------
 .. ||.| ...|. |  .  | |||||....  ..  ...|.| .|....     || .....|..     ..| .||..| ... .||  ||      
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNN

----KTKMLNATKKTIVAFDIARGMQYLHSKH--IIHRDLKSLNVLLNEE-----GQAKIGDFGYSRSYDSE-DSLLT--------QNIGTPHWMAPELL
    . . ||  ..   | |||.|| |||..   ||||||||.|.|....      ..|| ||| |.. ... .. ..         ..|.. |||||.|
NNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

DGT-TNYTNKVDVYAYAIVLWEIITGLQ------PYQGLDPPQIIAQVMI--HDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
 .  . |..|.|||...||||||.|. .      ||||.|. |... |      .|||.|.  .. ..|||..||...|. ||||.||..  
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase 81869.m00187.AA Dicty4 207-460 37 1.2e-73 245.07 In-house 1-277 (277) Show / Hide 
Range on Protein: 207-460
Range on HMM: 1-277/277
Sequence Identity: 37% (105 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLT--GIKLQTFQREISILAATSHPCLLKFVGATDT----QP--YCIITEWMDRDTLYRELHK--
    ..||.|  . |. |...  |  ||.|||. .. .     |. | .|..|..  .|| ...| ||  |    .|   || || | . .||. ||.  
INIEQRIGKGSFGEVYKGTWR--GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGAC-TAPRSHPGKMCIVTEYMPKGNLYSLLHDKP

-----TKMLN--ATKK-TIVAFDIARGMQYLHS--KHIIHRDLKSLNVLLNEEGQAKIGDFGYSR----SYDSEDSLLTQNIGTPHWMAPELLDGTTNYT
      . |     |.    |||.||||..||.    |||||||| | |  .  ..|..||| |.      |  | . |. .||| ||||| . .   |.
SEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTA-CGTPCWMAPEVMMHQ-PYN

NKVDVYAYAIVLWEIITGLQPYQ--GLDPPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKM--FYK
 |.||| ..|||||| |.  |||  . ...|... |  . ||||.|. . | .|.||..||| .| .|||||||..      
EKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase 81869.m00187.AA MLK 207-458 32 3.8e-73 249.31 In-house 1-291 (291) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-291/291
Sequence Identity: 32% (94 aa)

FEMIKEIGSGISSNVFYGRCKSTG---LPVAIKKLKFKK----LTGIKLQTFQREISILAATSHPC----LLKFVGA-TDTQP-YCIITEWMDRDTLYRE
..  . |||| .  |. ||.. .      ||.|. .. .     |.   . |..|. .|.  |||       .|.|. ..... .||..|...   ||. 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHKTKM--------------LNATKKTIVAFDIARGMQYLHSKH---IIHRDLKSLNVLLNE------EGQAKIGDFGYSRSYDSEDSLLTQNIGTPHWM
||  .                    .   |...||||.||||.    |||||||| |.|. |      .|..|| ||| ||.  . ..  . |.||. ||
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWM

APELLD--GTTNYTNKVDVYAYAIVLWEIITGLQPYQ-GLDPPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
||| .     . |. |.||. ...||||..|.  ||. ..|| .|...|  . ||||.|.| ....| |...||. .| .|||| .||. .
APEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase 81869.m00187.AA LRRK 207-460 26 2.1e-70 240.22 In-house 1-351 (351) Show / Hide 
Range on Protein: 207-460
Range on HMM: 1-351/351
Sequence Identity: 26% (92 aa)

FEMIKEIGSGISS-NVFYGRCKS--------------------------TGLPVAIKKLKFK---------KLTG-----------------------IK
..  ..||.| .  .|. .....                           . .|||||...            ..                        .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

LQTFQREISILAATSHPCLLKFVGATDTQPYCIITEWMDRDTLYRELHKTK-M--------LNATKKTIVAFDIARGMQYLHSKH--IIHRDLKSLNVLL
...|..|..|.    ||.... .| .  .|.|...| ..  .||. ||..| .        .. . |  .| .||.||.||||..  |||||||| |.||
FREFRHEVWIMSHLNHPNIVSLKGFC-IHPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---N---------EEGQAKIGDFGYSR--SYDSEDSLLTQNIGTPHWMAPELLD--GTTNYTNKVDVYAYAIVLWEIITGL-QPYQGLD-P-----PQII
   .         ..  |||.||| ||  ... . ...    |.| ||||| .   |. .|| |||.|.....|||..|.. .|....| .       .|
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHM-GVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQI

AQVMIHDLRPPLPQT-VNP-----GLKDLITRCWDRNPDRRPSFEEIVKMFYK
 . .|  |||..||.  .|      ..|||. ||. .|..||.|..|||    
EDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase 81869.m00187.AA HH498 207-458 32 4.6e-68 214.76 In-house 1-284 (284) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-284/284
Sequence Identity: 32% (94 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGIKLQ-------TFQREISILAATSHPCLLKFVGAT--DTQPYCIITEWMDRDTLYREL---
.|  . ||||   .|. |..   .  ||.|  . ..  . |          | ||.||.   .|||  .||.|.  |     |.|.. |   |.. |   
IEFHEKIGSGSFGKVYKGEWR--NKIVAVKRYRAMAF-CCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTI

-----------HKTK----MLNATKKTIVAFDIARGMQYLHS---KHIIHRDLKSLNVLLNEEGQAKIGDFGYSR-SYDSEDSLLTQNIGTPHWMAPELL
           |  |     .    | ... |.|.||.|||.   . |||||| | |.|. |.| |.. ||| ||   | .|  .|  .| . |||||  
PIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVF

DGTTNYTNKVDVYAYAIVLWEIITGLQPYQGLDPPQIIAQVMIHDLRPPLPQT----VNPGLKDLITRCWDRNPDRRPSFEEIVKMF
   . |. ||||. ||...||. |.  |.  . |    | .  |  |||.|||    .      || .||. .|. ||.| .|| . 
SQCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase 81869.m00187.AA S_TKc 207-460 27 2.7e-67 230.81 SMART 1-231 (231) Show / Hide 
Range on Protein: 207-460
Range on HMM: 1-231/231
Sequence Identity: 27% (73 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGIKLQTFQREISILAATSHPCLLKFVGATDTQPYCIITEWMDR--DTLYRELHKTKM-----
.|....||.|  . |. .| |.||  ||||..|         ....|||.||    || . |. .. ... .....| .|    .|.. ..| .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LNATKKTIVAFDIARGMQYLHSKHIIHRDLKSLNVLLNEEGQAKIGDFGYSRSYDSEDSLLTQNIGTPHWMAPELLDGTTNYTN-KVDVYAYAIVLWEI
 ..      ..  |.....|.||..|||||||  |.||.|  . ||.||| .| .       |  .|||..||||.|     |.  |.|...  ..|.| 
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEM

ITGLQPYQGLDPPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVK-------MFYK
..|  |..    .| . ...             | .||.| .|....|..||.  |. .       . . 
LCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81869.m00187.AA Pkinase 207-458 27 1.3e-65 229.1 Pfam 1-293 (293) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-293/293
Sequence Identity: 27% (80 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGIKLQTFQR--EISILAATSHPCLLKFVGAT-DTQPYCIITEWMDRD----TLYRELH---K
.. .. |||| .. |. .. |.||  ||.|..| ..    |.||  |  ||.|..  .||. ... ..  | . .....|... .     |.. ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TKMLNATKKTIVAF--DIARGMQYLHSKHIIHRDLKSLNVLLNEEGQA----KIGDFGYSRSY-DSEDSLLTQNIGTPHWMAPELLDGTTNYTNKVDVYA
....  . ...  .   |.||..|.||. |||||||. |.|....|.     ||.||| .. .    .| .|   |||..||||.. | . |. |||...
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

YAIVLWEIITGLQPYQGL------DPPQIIAQVMIHDLRPPLPQTVN-------------------PGLKDLITRCWDRNPDRRPSFEEIVKM--F
. ..|.| ..|  |..|       |. |.|...|  .|. . |.. .                   . .||.|..|....| .||..|.|..   |
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81869.m00187.AA Pkinase_Tyr 207-458 30 2.2e-62 211.91 Pfam 1-270 (270) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-270/270
Sequence Identity: 30% (83 aa)

FEMIKEIGSGISSNVFYGRCK----STGLPVAIKKLKFKKLTGIK---LQTFQREISILAAT-SHPCLLKFVGA-T-DTQP--YCIITEWMDRDTLYREL
 ...|..|.|   .|. |..|    .|..|||.|.|  |  .  .   .. | ||..|.    .|| .....|. | . .|  ..|..| |    |.  |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML--KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HK----TKMLNATKKTIVAFDIARGMQYLHSKHIIHRDLKSLNVLLNEEGQAKIGDFGYSRSY--DSED-SLLTQNIGTPHWMAPELLDGTTNYTNKVDV
.|     . |.   .   ...||.||.||.||..|||||   |.|..|....||.||| .|    |..     .       ||||| .     .| | ||
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDV

YAYAIVLWEIIT-GLQP-YQGLDPPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
... ...|||.| | || |.|... ......  .  | | |.   . . ||...||. .|..||.|.||. ..
WSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase 81869.m00187.AA Dicty4-Unclassified 207-458 34 2.8e-61 208.63 In-house 1-263 (263) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-263/263
Sequence Identity: 34% (93 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGI--KLQTFQREISILAATSHPCLLKFVGATDTQP------YCIITEWMDRDTLYRELH---
    ..|| |  | |  |  |  |  ||.||.   |       .| | .|. ||   .|| |.|  |.    |      .||..| | . .|    |   
IQIDQFIGKGHFSKVHKGNWK--GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYC-INPRSHKSTMCIVMEFMHKGNLFEVIHSKP

--KTKMLNATKKTIV--AFDIARGMQYLHSKHIIHRDLKSLNVLLNEEGQAKIGDFGYSRSYDSEDSLLTQNIG-TPHWMAPELLDGTTNYTNKVDVYAY
  . . .      |.  |||||.|||.||.. .||||.|| |.|.     .||.||| ||  |    . |  |. || | .|| | .   |. | ||| |
SEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTT--IAGTPKWESPECLMHES-YNQKSDVYSY

AIVLWEIITGLQPYQGLD-PPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
|..|.| .||  |||.   .  .   |    ||| .|  . . .| ||  ||   | .||....|..  
AMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase 81869.m00187.AA Dicty5 208-464 35 1.1e-59 204.15 In-house 2-260 (260) Show / Hide 
Range on Protein: 208-464
Range on HMM: 2-260/260
Sequence Identity: 35% (95 aa)

EMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGIKLQTFQREISILAATS--HPCLLKFVGA-TDTQPY-CIITEWMDRDTLYRELHKTKM----
 . . | || |  |. |  |  |  |||| .      .  .. |.||. |. .    || . .. || .  . |  ..||   . .|   |   .     
SFHDWIASGASGRVYNGIYK--GMDVAIKVYSQENCMCFDWNEFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQ

-LNATKKTIVAFDIARGMQYLHSKHIIHRDLKSLNVLLNEEGQAKIGDFGYSRSYDSEDSLLTQNIGTPHWMAPELLDGTTNYTNKVDVYAYAIVLWEII
 .    .   | |||..|..|||. ||||||||.|.|..|. ..|| ||| ||  |      | ..||. |||.||  | . |..|.|||...|||||..
PIAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYH-MTMHVGTQCWMACELFNGQP-YHQKCDVYSFGIVLWEMF

TGLQPYQGLDPPQIIAQVMIHDLRPPLPQTVNPGLKDLITRCWDRNPDRRPSFEEIVKMFYKNQII
|   ||  .    |   ||  . || .| ..      ||  ||   | .|||| ||.|.| .  ||
TRKEPYDNINNWNIPVMVMKGE-RPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFES--II
Kinase 81869.m00187.AA TK 207-458 16 6.3e-59 195.85 In-house 1-486 (486) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-486/486
Sequence Identity: 16% (79 aa)

FEMIKEIGSGISS---NVFYGRCKSTG-------------------------LPVAIKKLKFKKLTGIKLQT---------------FQREISILA--AT
 ...|..|.|       |. |. .. .                          |||.| || .  .  . .                . .|....   . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

SHPCLLKFVG-ATDT------------QPYCIITEWMDRDT----LYRELHKTKM---------------------------------------------
 || .....|  |.             .|..|..|.|.       |   |.| .                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LNATKKTIVAFDIARGMQYLHSK------HIIHRDLKSLNVLLNEEGQ-----------AKIGDFGYS-
                               |.   .   ...||.||.|||||      ...||||   |.|..|...           .||.||| | 
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-------RSYDS-EDSLLTQNIGTPH-------------------------WMAPELLDG--------TTNYTNKVDVYAYAIVLWEIIT-G-LQPYQGL
       |  .| .|   ... ||.                          ||||| |..        .  .| | ||... ...||| | |  ..| |.
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

DP---------PQIIAQVMI-------------HDLRPPLPQTVN--------------PGLKDLITRCWDRNPDRRPSFEEIVKMF
.           ... ..               . .|.| |.                 . . ||...||...|..||.|.......
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase 81869.m00187.AA TyrKc 207-458 28 8.2e-55 189.33 SMART 1-280 (280) Show / Hide 
Range on Protein: 207-458
Range on HMM: 1-280/280
Sequence Identity: 28% (83 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKLKFKKLTGIKLQTFQREISILAAT--SHPCLLKFVGATDT--------QPYCIITEWMDRDTLYRELHK
 ...|..|.|    |. |. |   ..||.|.||  .     .. | ||..|.     .||......|.  .        .|..|..| |.   |   |.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TKM-LNATKKTIVAFDIARGMQYLHSKHIIHRDLKSLNVLLNEEGQAKIGDFGYSRSYDSE-------DSLLTQN-IGTP-----HWMAPELLDGTTN-Y
..  |.  ..   ...||.||.|||||..|||||   |.|..|....||.||| ||  ...       |   ..   |.       ||||| .   .. .
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF

TNKVDVYAYAIVLWEIIT-GLQPYQG-----LDPPQIIAQVMIHDLRPPLPQ-------TVNPGLKDLITRCWDRNPDRRPSFEEIVKMF
| | ||... ...||| | | ||| |     ... ..|..|.  . .|. |        .  . . .....||...|. ||.|.||.. |
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 81869.m00187.AA CZAK 309-458 42 6.4e-50 172.16 In-house 111-279 (279) Show / Hide 
Range on Protein: 309-458
Range on HMM: 111-279/279
Sequence Identity: 42% (73 aa)

AFDIARGMQYLHS--KH--IIHRDLKSLNVLLNEEGQ-------------AKIGDFGYSRSYDSEDSLLTQNIGTPHWMAPELLDGTTNYTNKVDVYAYA
| |||||| |||   |   |.|||| | |.||..                .|| ||| ||      .  || .|   |||||   |  ||| ||||| ..
AIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKG-ENYTEKVDVYSFG

IVLWEIITGLQPYQGLDPPQIIAQVMIHDLRPPLPQTVNPGLK---DLITRCWDRNPDRRPSFEEIVKMF
..||.|||. ||||.. |  .       . |||.||.  |  |    ||..||. ||| |||| .|.   
MILWCIITCDQPYQNMQPMKMAHLAAYENYRPPMPQPMDPMWKNLGELIEMCWNKNPDERPSFKQILQHL
Kinase 81869.m00187.AA CZAK 207-285 29 7.1e-10 32.2 In-house 1-84 (279) Show / Hide 
Range on Protein: 207-285
Range on HMM: 1-84/279
Sequence Identity: 29% (25 aa)

FEMIKEIGSGISSNVFYGRCKSTGLPVAIKKL---KFKKLTG-IKLQTFQREISILAATSHPCLLKFVGA-TDTQ--PYCIITEWM
..  ..|| |    |  .. .  |  ||||..   .|. ...   .  ||.|.||.    ||  . |.|| . .     ||..|||
LKFGQTIGQGFFGEVYKAYWR--GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWM