Gene 95238.m00109 (T.vaginalis)

95238.m00109

Species: T.vaginalis
Alias: 95238.m00109, TvagK0432
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
95238.m00109.AA Protein None 430 None Fasta, JSON
95238.m00109.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 95238.m00109.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 95238.m00109.AA PH 5-98 26 1e-06 26.68 Pfam 1-92 (92) Show / Hide 
Range on Protein: 5-98
Range on HMM: 1-92/92
Sequence Identity: 26% (25 aa)

STTGGWLSKRGLLGIWSQRYCKLIGTQLVISKSEKINNSEQTIEINPNAKIQIVSDQKKPRFFLEDTNGE-TALLEAKSTQEMMQWVLLLRGATF
 .  |||.|.| .. | .|.. | ...|.. |..|  .   .| ..   .. .|.|.|.|  |   | .. | ...|.| .|| .|.  .. |  
VIKEGWLHKKGKRKSWKKRWFVLFNNCLYYYKDDK-YRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
PH 95238.m00109.AA PH 5-100 18 2e-06 28.35 SMART 1-82 (82) Show / Hide 
Range on Protein: 5-100
Range on HMM: 1-82/82
Sequence Identity: 18% (18 aa)

STTGGWLSKRGLLGIWSQRYCKLIGTQLVISKSEKINNSEQTIEINPNAKIQIVSDQKKPRFFLEDTNGETALLEAKSTQEMMQWVLLLRGATFWN
 .  |||.|.. .  | .|.. | . .|.. |..       .| ..   ...         | .   .. | .. ..| .|| .|.  .. |.  |
VIKEGWLYKKS-K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P-----CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 95238.m00109.AA AGC 108-359 28 4.4e-152 396.4 In-house 1-395 (395) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-395/395
Sequence Identity: 28% (112 aa)

FEVISVIGQGYYGKVRLVKSK------ADGELFAIKSIRKSK-LIEQK--EIKTVLNE------------RNIMIKAD----------HPFIVQ-LKFAF
||.. |||.| .|||.||. |      . |...|.| ..|..  .. |  ... ...|            |||. |..          |||||. |...|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QSSSK--FYLGLEYVP---------GG-ELFAHIK---RDGFLHEEEYKLVLAQ-------VALVLNHLHS-IGVIYRD-MKPENIMIGQDGYIKLTDFG
|. ..   |. .||.|         || ||| |..   . | . ||. .  .|.       ..| | .|||  |.|.|| .|||||.. .||.|||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKDITVE---------------------------------------------------DTTSTFCG--TPDYIAPEVVRGLNYDKSVDWWA--LGILAF
|.| .  .                                                   |.|.||||  ||.|.|||..    |.|..|||.  ||.| .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

ELMYHRTPFHSQN----------RDKTYRKIV------NDSPKFP----------EYASEVEKSFIMGLLNKEPKQRFG----------FKEVKEHQFF
|... ..||...|          ..... ||       |. .|||          .. |.  |..| .||.|.|..| |          ..|.|.| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 95238.m00109.AA Akt 108-359 42 9.20000000001e-121 387.79 In-house 1-264 (264) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-264/264
Sequence Identity: 42% (112 aa)

FEVISVIGQGYYGKVRLVKSKADGELF-AIKSIRKSKLIEQKEIKTVLNERNIMIKADHPFIVQLKFAFQSSSKFYLGLEYVPGGELFAHIKRDGFLHEE
|... |.|.| .||| ||| |...... |.|...|...|...... .. ||||  . .|||||.|...||.. | |. ..|..||||| |..|...  |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

EYKLVLAQVALVLNHLHSIGVIYRD-MKPENIMIGQDGYIKLTDFGLAK-D-ITVEDTTSTFCGTPDYIAPEVVRGLNYDKSVDWWA-LGILAFELMYHR
. .   |.. | . |||| ..|||| .|||||.. .||.|.||||||.| . |.  |.| |||||| |.|||.  |  ..|.||||. ||.. .|.|. |
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFHSQNRDKTYRKIVNDSPKFP--EYASEVEKSFIMGLLNKEPKQRFG-----FKEVKEHQFF
 ||..|.... . || |   |||  .. |   |..| ||||| ||.| |      .|.|.| .|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 95238.m00109.AA SGK 108-359 40 3.1e-114 354.27 In-house 1-283 (283) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-283/283
Sequence Identity: 40% (114 aa)

FEVISVIGQGYYGKVRLVKSKAD------------------GELFAIKSIRKSKLI-------EQKEIKTVLNER-NIMIKADHPFIVQLKFAFQSSSKF
|. ..|||.| .||| .|| |.|                  . ..|.| ..|   |         || | .. || .|. .  |||||.|..|||   | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYVPGGELFAHIKRDGFLHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAK-DITVEDTTSTFCGTPDYIAPEVVRGL
|. ..|| |||.| |..| . . | . .   |.... | .|||. .|||| |||||. . .|...||||||.| .|  .|||.|||||| | |||| |. 
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NYDKSVDWWALGILAFELMYHRTPFHSQNRDKTYRKIVNDSPKFPEYASEVEKSFIMGLLNKEPKQRFGFK----EVKEHQFF
 .|..|||| ||.. .|.||   || |.|.   | .| |   ..| . |   .. | |||.|.||.| | |    |.|.|.||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 95238.m00109.AA AktR 108-359 39 5e-108 365.18 In-house 1-268 (268) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-268/268
Sequence Identity: 39% (106 aa)

FEVISVIGQGYYGKVRLVKSK-ADGELFAIKSIRKSKLIEQKEIKTVLNERNIMI-KADHPFIVQLKFAFQSSSKFYLGLEYVPGGELFAHIKRDGFLHE
|.|. ..|.| .||| ||. |  .....|.|.|.|.|.||.. .. ...|||||. ...|||||.|...||. .| .. .||.|||||| |.|..... |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EEYKLVLAQVALVLNHLHSI-GVIYRDMKPENIMIGQDGYIKLTDFGLAK---DITVEDTTSTFCGTPDYIAPEVVRG-LNYDKSVDWWALGILAFELMY
|. .   ||. | | .||.   .||||.|||||....||..|.|||||.|   ..  .... .||||| |.|||...    ..|||||||.||. .|...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

HRTPFHSQNRDKTYRKIVNDS---PKFPEYASEVEKSFIM-GLLNKEPKQRFG-----FKEVKEHQFF
  .|| ..|.   . || .     ...|.| |.  |..|  .||.| |..| |     ..|.|.| .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 95238.m00109.AA S_TKc 108-359 32 4.5e-100 339.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVLNERNIMIKADHPFIVQLKFAFQSSSKFYLGLEYVPG--GELFAHIKRDGF---
.|.. .||.| .|||.... | .|...||| |.          .....|..|. | .||.||.|. .||. ...|. .||..|  |.|| .||. |    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDITVEDTTSTFCGTPDYIAPEVVRGLNYDK-SVDWWALGILAFEL
   ..| . . ...|... |...|| |.|.|| |||||.. .   ||..|||||. .      .||||||.|.||||.    |.| ..|||..|.. .|.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

MYHRTPFHSQNRDKTYRKIVNDSPKFPEYASEVEKSFIMGLLNKEPKQRFGFKEVKE-------HQFF
.. ..||.  . .....||.          |.  |.||...|.|.|..| .  |. .       |..|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95238.m00109.AA RSK 111-359 36 1.9e-96 326.74 In-house 1-278 (278) Show / Hide 
Range on Protein: 111-359
Range on HMM: 1-278/278
Sequence Identity: 36% (101 aa)

ISVIGQGYYGKVRLVKSK---ADGELFAIKSIRKSKLIE-QKEIKTVLNERNIMIKAD-HPFIVQLKFAFQSSSKFYLGLEYVPGGELFAHIKRDGF---
..| ||| |||| |.. .   . | ..| | ..|.|..  || ..... ||||.     |||||.|. |||  .|.|| .||..||||| |... ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQ---DGYIKLTDFGLAKDITVE--DTTSTFCGTPDYIAPEVVR---GLN-YDKSVDWWALGI
. |.| . ..|...| . |||. |.|.|| |||||.  .   .| |||||||..|    .    | |||.| .|.|||...   . . .||..||| ||.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAFELMYHRTPFHS---QNRDKTYRKIVNDS--PKFP--EYASEVEKSFIMGLLNKEPKQRFG-----FKEVKEHQFF
| .|.   ..||..   .||... ..| .    ...|  .| |.  |..| ..| ..|..| |      .|.|.|..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 95238.m00109.AA PKA 108-359 38 5.8e-94 318.47 In-house 1-263 (263) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-263/263
Sequence Identity: 38% (103 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVLNERNIMIKADHPFIV-QLKFAFQSSSKFYLGLEYVPGGELFAHIKRDGFLHEE
|| | ..|.| .|.|.|...| .|. .|.| ..|.. .  | .  |.||.||.   .||||| .... || ... |. .|||||||.| .. . | . . 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

EYKLVLA-QVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDITVEDTTSTFCGTPDYIAPEVVRGL-NYDKSVDWWALGILAFELMYHRTP
. |.  | |. | |  |||   |||| |||||.| ..|.||.|||| || ..    |.| ||||.|.|||.. .   . ||||||||||| .|..   .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FHSQ--NRDKTYRKIVNDSPKFPEYASEVE---KSFIMGLLNKEPKQRF-----GFKEVKEHQFF
|     .  ..|.||.|   |||.. .  .   |..|  ||.. ...|.     |   .|.| .|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 95238.m00109.AA RSK-Unclassified 108-359 34 3.3e-90 283.53 In-house 1-283 (283) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-283/283
Sequence Identity: 34% (98 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVLNERNIMIKADHPFIVQLKFAFQSSSKFYLGLEYVPGGELFAHIK--RDGFLHE
|...  ||||  ||| ||. |    ..|.|   |.|.| .. || |. |.|||   .|||||.| ..||.. . || .|| .||..| |    ..  . |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

EEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDI--------------------TVEDTTST--FCGTPDYIAPEVVRGLNYD
.. .  .. | . | .||  ..||||.||.||.  |.| ..||||.| ..                      ... . |  |||| .|.|||..|.    
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

KSVDWWALGILAFELMYHRTPFHSQNRDKTYRKIVNDSPKFP--EYASEVEKSFIMGLLNKEPKQRFGFK-----EVKEHQFF
| |||| |||. .|..   .|.   |.. |.  |     |||  .| |   .. |  ||.. |  | | |     ..| |.||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 95238.m00109.AA PKC 108-359 37 3.2e-89 289.34 In-house 1-262 (262) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-262/262
Sequence Identity: 37% (98 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVLNERNIMIKAD-HPFIVQLKFAFQSSSKFYLGLEYVPGGELFAHIKRDGFLHEE
|. . |.| | .||| |...|   |..||| ..|   |.   .  ...|. ..  |  ||| ..|   ||. .. .  .||| || |  || . . . ||
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

EYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKD-ITVEDTTSTFCGTPDYIAPEVVRGLNYDKSVDWWALGILAFELMYHRTPF
  .   | ... |. ||. |.|||| | .|... ..| ||..|||..|. .. .||||||||||||||||....  | |||||||.|.| .|.|  . ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

HSQNRDKTYRKIVNDSPKFPEYASEVEKSFIMGLLNKEPKQRFGF--------KEVKEHQFF
| .. |   . | .| | .| . |.  .| . |...|.|..| |         ....||.||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 95238.m00109.AA Pkinase 108-359 31 1.6e-88 305.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-293/293
Sequence Identity: 31% (92 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVL-NERNIMIKADHPFIVQLKFAFQSSSKFYLGLEYVPGG----ELFAHIK--RD
......||.| .|.|.. . | .|...|.| |.|..  ..|..  .. .|  || . .||.||.|. .|..... |. .||..||    .||..|.  |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GFL--HEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYI----KLTDFGLAKD--ITVEDTTSTFCGTPDYIAPEVVR-GLNYDKSVDWWAL
| .   |.| | .. |..  |...|| |.|.||.|||||.| ..|.|    |..||||||   .     ..||||||.|.||||.| |  |...||.|..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILAFELMYHRTPFHSQ------NRDKTYRKIVNDSPKFPEYAS---------------------EVEKSFIMGLLNKEPKQRFGFKEVKEHQFF
|.. .|..  |.|| ..      . .. ...|    ..|... .                     |  |.|| ..|.| ||.| .......| .|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 95238.m00109.AA Ciliate-E2 108-359 22 1.4e-83 284.03 In-house 1-365 (365) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-365/365
Sequence Identity: 22% (85 aa)

FEVISVIGQGYYGKVRLVKS-----------------------KADGELFAIKSIRKSKLIEQKEIKTVL----------NERNIMIKADHPFIVQLKFA
...| .|||| .|.|...|                        |... ..|.|...|......| .. ..          ||.||. . .||.|.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--SSSKFYLGLEYVPGGELFAHIK------------RDGFLHEEEYKLVLAQVAL---------------VLNHLHSIG-VIYRDMKPENIMIGQDGY
||  . ...|| .||. ||.|| .||              . . |.| | . .|..                 |..||| . .|.|| |||||..     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IKLTDFGLAKDITVE--------------------------------DTTSTFCGTPDYIAPEVVRGLN---------YDKSVDWWALGILAFELMYHRT
||..||||.|... .                                ... |.|||| | |||...| .         ||...|.|.||.. .|... ..
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFHSQNRDKTYRKIVNDSPKFPEYASEVE------------------KSFIMG----LLNKEPKQRFG-FKEVKEHQFF
||        ...| .   .||.. .. .                  | .|      .|.|.|..|.. ......|..|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 95238.m00109.AA p70 108-359 35 2e-83 283.5 In-house 1-299 (299) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-299/299
Sequence Identity: 35% (107 aa)

FEVISVIGQGYYGKVRLVKSKA---DGELFAIKSIRKSK-LIEQKEIKTVL-------------------------NERNIMIKADHPFIVQLKFAFQSS
|| . |.|.| |||| .|.  .    | ..| | .|| | .. ||                                ||||     ||||. | .|||  
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

SKFYLGLEYVPGGELFAHIKRDGFLHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDITVEDTT-----------STFCG
.| || ||| .||||| | .| | . |.  .  |. . . | |||. |.|||| ||||.|  | | ..|||||| |    ...             ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TPDYIAPEVVRGLNYDKSVDWWALGILAFELMYHRTPFHSQNRDKTYRKIVNDS--PKFPEYASEVEKSFIMGLLNKEPKQRFG-----FKEVKEHQFF
|. | |||....  ... ||||.||.| .  .    ||   || ||  ||      .| | | ..  .  |  || ..|.|| |      ....||.||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 95238.m00109.AA TyrKc 108-359 19 4.4e-15 21.22 SMART 1-280 (280) Show / Hide 
Range on Protein: 108-359
Range on HMM: 1-280/280
Sequence Identity: 19% (58 aa)

FEVISVIGQGYYGKVRLVKSKADGELFAIKSIRKSKLIEQKEIKTVLNERNIMIKA--DHPFIVQLKFAFQSS-------SKFYLGLEYVPGGELFAHI-
 . . ..| | .|.|.. . |   .  |.|......      ..  ..| .|| |   .|| ||.|  .  ..          .. .||.|.| |  .. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KRDGFLHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDITVE-------DTTSTFC--GTPD-----YIAPEVVRGLNYD
|. . |  ..      |.|   ..||| ..| ||    |...| .. .| .||||..||. .       |. ..    |. .       |||. .   . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KSVDWWALGILAFELM-YHRTPFHS-----QNRDKTYRKIVND-SPKFPEY--------ASEVEKSFIMGLLNKEPKQRFGFKEVKEHQFF
   | |. |.. .|.. |  .|         . .  .... .   .. |..        ...   . .    . .|..|  |.|.  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 95238.m00109.AA S_TK_X 360-420 26 1.6e-11 45.5 SMART 1-79 (79) Show / Hide 
Range on Protein: 360-420
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

GNINFDDVLA--KKIQPYYVPQIE----DPTNVKYFDAEFTNETKADSFVAP----IIGDEA--------VVPGFSYVE
 .|..|....  |.|.| ..|.|     .|| ...|| |||.||  .. . |    ... ..          .||.|| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 95238.m00109.AA Pkinase_Tyr 108-261 23 2.6e-08 28.78 Pfam 1-166 (270) Show / Hide 
Range on Protein: 108-261
Range on HMM: 1-166/270
Sequence Identity: 23% (39 aa)

FEVISVIGQGYYGKVRLVKSK----ADGELFAIKSIRKSKLIEQKE--IKTVLNERNIMIKA-DHPFIVQLKFAFQ-SSSK--FYLGLEYVPGGELFAHI
 . . ..|.| .|.|.. . |     ..   |.|...      ...  ..  ..| .|| .  .|| ||.|  .    .     |. .||.|.| |  . 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

KR----DGFLHEEEYKLVLAQVALVLNHLHSIGVIYRDMKPENIMIGQDGYIKLTDFGLAKDITVEDT
..    .. |  ..     .|.|  ...|.|.. | ||    |.... .. .| .|||||.||. .|.
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY